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| Product | Description | |
|---|---|---|
| Astragaloside A | Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. Alternative Names: Cyclosiversioside F; (3b,6a,16b,24R)-20,24-Epoxy-16,26-dihydroxy-3-(b-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl b-D-glucopyranoside. Grades: >98%. CAS No. 83207-58-3. Molecular formula: C41H68O14. Mole weight: 784.97. |  |
| Astragaloside I | Astragaloside I is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside I has cardioprotective effects as well as causing improvement in cognitive function. It has anti-gastric effect. It has been shown to increase gastric pH without changing gastric volume or acid output. Uses: Astragaloside i has cardioprotective effects as well as causing improvement in cognitive function. it has anti-gastric effect and could increase gastric ph without changing gastric volume or acid output. Alternative Names: (3β,6α,16β,20R,24S)-3-[(2,3-Di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside; Astrasieversianin IV; Cyclosieversioside B; (2S,3R,4S,5R)-5-Hydroxy-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-hydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-9-yl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate. Grades: >98%. CAS No. 84680-75-1. Molecular formula: C45H72O16. Mole weight: 869.04. | |
| Astragaloside I | Astragaloside I. Group: Biochemicals. Alternative Names: Astrasieversianin IV; Cyclosieversioside B; Cyclosiversioside B. Grades: Plant Grade. CAS No. 84680-75-1. Pack Sizes: 20mg. Molecular Formula: C45H72O16, Molecular Weight: 869.054999999999. US Biological Life Sciences. |  Worldwide |
| Astragaloside I | Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through activating the Wnt/β-catenin signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Astrasieversianin IV; Cyclosieversioside B. CAS No. 84680-75-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0432. |  |
| Astragaloside II | Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Astrasieversianin VIII. CAS No. 84676-89-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0433. | |
| Astragaloside II | Astragaloside II. Group: Biochemicals. Alternative Names: Astrasieversianin VIII; Cyclosieversioside D; Cyclosiversioside D. Grades: Plant Grade. CAS No. 84676-89-1. Pack Sizes: 20mg. Molecular Formula: C43H70O15, Molecular Weight: 827.006999999999. US Biological Life Sciences. | Worldwide |
| Astragaloside II | Astragaloside II is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. It is used in the prevention of cardio-cerebral vascular diseases. It stimulates osteoblast differentiation resulting in bone formation. It exhibits a significant induction of proliferation, differentiation and mineralization in primary osteoblasts. It is a potent MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Uses: Astragaloside ii has cardioprotective effects as well as causing improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it may be used as a potential adjunctive agent for hepatic cancer chemotherapy. Alternative Names: (3b,6a,16b, 20R,24S)-3-[(2-O-Acetyl-b-D-xylopyranosyl)oxy]-20,24-Epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl b-D-glucopyranoside; Astrasieversianin VIII. Grades: >98%. CAS No. 84676-89-1. Molecular formula: C43H70O15. Mole weight: 827.01. | |
| Astragaloside III | Astragaloside III. Group: Biochemicals. Grades: Plant Grade. CAS No. 84687-42-3. Pack Sizes: 5mg. Molecular Formula: C41H68O14, Molecular Weight: 784.97. US Biological Life Sciences. | Worldwide |
| Astragaloside III | Astragaloside III is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Uses: Astragaloside iii has cardioprotective effects as well as causes improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it is an antioxidant. Alternative Names: (3b,6a,16b,20R,24S)-20,24-Epoxy-6,16,25-trihydroxy-9,19-cyclolanostan-3-yl12-O-b-D-glucopyranosyl-b-D-xylopyranoside. Grades: >98%. CAS No. 84687-42-3. Molecular formula: C41H68O14. Mole weight: 784.97. | |
| Astragaloside III | Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84687-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0434. | |
| Astragaloside IV | Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 84687-43-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0431. | |
| Astragaloside IV | Astragaloside IV. Group: Biochemicals. Alternative Names: Astrasieversianin XIV; Cyclosieversioside F; Cyclosiversioside F; Astramembrannin I; Astragaloside A. Grades: Plant Grade. CAS No. 84687-43-4. Pack Sizes: 20mg. Molecular Formula: C41H68O14, Molecular Weight: 784.97. US Biological Life Sciences. | Worldwide |
| Astragaloside IV | Astragaloside IV is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. It has anti-aging properties, antioxidant, anti-inflammatory and anti-fibrotic effects in systemic sclerosis. It inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-α-ERK1/2-NF-κB pathway. Astragaloside IV is a natural compound used in cosmetics material. Uses: Cardiovascular protection. Alternative Names: 9,19-Cyclolanostan-beta-D-glucopyranoside; 20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl. Grades: >98%. CAS No. 84687-43-4. Molecular formula: C41H68O14. Mole weight: 784.97. | |
| Astragaloside IV (Standard) | Astragaloside IV (Standard) is the analytical standard of Astragaloside IV. This product is intended for research and analytical applications. Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 84687-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0431R. | |
| Astragalus Extract | Astragalus extract is derived from the root of Astragalus Membranaceus in the pea family. Astragalus root extract has been widely used in Chinese medicine for hundreds of years, and is well known for the effects this herb can have with your immune system. Astragalus extract astragaloside has been used to promote the discharge of urine, lower blood pressure, and increase endurance. Group: Others. Mole weight: 784.97. Astragalus Extract; Astragalus membranaeus Bge. Cat No: EXTC-031. |  |
| Astragalus Root P.E. 10:1 | Astragalus Root P.E. 10:1. |  CA, FL & NJ |
| Astragalus Root Powder | Astragalus Root Powder. | CA, FL & NJ |
| Astrazon Pink | Astrazon Pink. Alternative Names: Astrazon Pink; Basic Red 13; Cationic pink FG. Grades: 95%. CAS No. 3648-36-0. Molecular formula: C22H26Cl2N2. Mole weight: 584.28. | |
| Astressin | Astressin is a novel potent corticotropin releasing factor (CRF) antagonist. Astressin may be a useful tool to explore functional CRF-dependent physiological pathways in specific brain nuclei. Uses: Neuroprotective agents. Alternative Names: (D-Phe12,Nle21·38,Glu30,Lys33)-CRF (12-41) (human, rat); H-D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu(1)-Ala-His-Lys(1)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2. Grades: ≥95%. CAS No. 170809-51-5. Molecular formula: C161H269N49O42. Mole weight: 3563.16. | |
| Astressin | Astressin is a potent corticotropin releasing factor (CRF) antagonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 170809-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0257. | |
| Astressin 2B | Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 681260-70-8. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1108. | |
| Astressin 2B | Astressin 2B. Group: Biochemicals. Grades: Purified. CAS No. 681260-70-8. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Astressin 2B | Astressin 2B is a selective and potent corticotropin-releasing factor receptor 2 (CRF2) antagonist with IC50 values of > 500 nM and 1.3 for CRF1 and CRF2 respectively. It antagonizes CRF2-mediated inhibition of gastric emptying. Alternative Names: Cyclo(31-34)[D-Phe11,His12,C(α)MeLeu13,39,Nle17,Glu31,Lys34]Ac-Svg(8-40). Grades: >98%. CAS No. 681260-70-8. Molecular formula: C183H307N49O53. Mole weight: 4041.69. | |
| Astressin 2B TFA | Astressin 2B TFA is a selective and potent corticotropin-releasing factor receptor 2 (CRF2) antagonist with IC50 values of > 500 nM and 1.3 for CRF1 and CRF2 respectively. It antagonizes CRF2-mediated inhibition of gastric emptying. Grades: 98%. Molecular formula: C183H307N49O53.xC2HF3O2. Mole weight: 4041.69 (free base). | |
| Astringin | Astringin (trans-Astringin) is an orally active natural phenolic stilbene glucoside. Astringin can inhibit the production of oxidative stress, inflammatory factors, etc. Astringin has multiple activities such as anti-oxidation, anti-inflammation, and anti-apoptosis. Astringin is also an inhibitor of ferroptosis. Astringin can be used in the research of diseases such as acute lung injury[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-Astringin. CAS No. 29884-49-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4093. | |
| Astrocytes Transfection Reagent | Reagents optimized for high-efficient delivery of DNA and RNA into Astrocyte cells. Uses:
| |
| Astrocyte Transfection Reagent | Transfection Reagent for Astrocyte Cell Lines and Primary Astrocytes. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1712. |  Nevada, Texas, USA |
| Astrophloxine | Astrophloxine is a positively charged, fluorescent probe used for detecting the microenvironment changes surrounding cell membranes. Alternative Names: 1-Ethyl-2-[3-(1-ethyl-3,3-dimethyl-1,3-dihydro-indol-2-ylidene)-propenyl]-3,3-dimethyl-3H-indolium iodide; 1,1'-Diethyl-3,3,3',3'-tetramethylindocarbocyanine iodide. CAS No. 14696-39-0. Molecular formula: C27H33IN2. Mole weight: 512.48. | |
| Astrophloxine | A fluorescent dye. Group: Biochemicals. Alternative Names: 1, 1'-Diethyl-3, 3, 3', 3'-tetra methyl indocarbocyanine Iodide; 1-Ethyl-2-[3-(1-ethyl-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene)-1-propen-1-yl]-3,3-dimethyl-3H-indoliumIodide; Astrophloxin; SNC 2. Grades: Highly Purified. CAS No. 14696-39-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| ASTX029 | ASTX029 (Example 1) is a potent dual ERK1/2 inhibitor (IC50: 2.7 nM). ASTX029 has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095719-92-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126288. | |
| ASTX295 | ASTX295 is an orally active and selective MDM2 antagonist with an IC50 of <1 nM. ASTX295 inhibits the MDM2-p53 interaction, activates wild-type TP53, and thereby induces the expression of relevant transcriptional targets, leading to cell death. ASTX295 drives the transition of pancreatic cancer cells from senescence to apoptosis and regulates p53 and DNA damage biomarkers. ASTX295 can be used for the research of hematologic malignancies and pancreatic cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093449-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-176083. | |
| AsuC2 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion less than 10% of the dna fragments can be ligated. Group: Restriction Enzymes. Purity: 2000U; 10000U. CC↑SGG GGS↓CC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Actinobacillus suis CA. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: RE-1027EN. | |
| AsuHP I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme about 30% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GGTGA(N)8↑ CCACT(N)7&darr. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Actinobacillus suis HP. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1028EN. | |
| Asukamycin | Asukamycin, a manumycin-type metabolite, is isolated from Streptomyces nodosus subsp. asukaensis. It exhibits antibiotic properties and inhibits the growth of various tumor cell lines. Alternative Names: asukamycin A1; Manumycin F; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-, (2E,4E,6E)-. Grades: >98%. CAS No. 61116-33-4. Molecular formula: C31H34N2O7. Mole weight: 546.61. | |
| asulam | asulam. Alternative Names: mb 9057; METHYL SULFANILYLCARBAMATE; Methyl [(4-aminophenyl)sulfonyl]carbamate; METHYL 4-AMINOPHENYLSULPHONYLCARBAMATE; ASILAN; ASULAM; asulox; ASULOX 40. CAS No. 3337-71-1. Molecular formula: C8H10N2O4S. Mole weight: 230.24. | |
| Asulam | Carbamate herbicide; folic acid biosynthesis inhibitor. Group: Biochemicals. Alternative Names: N-[ (4-Aminophenyl) sulfonyl]carbamic Acid Methyl Ester; Sulfanilylcarbamic Acid Methyl Ester; Asulox F; MB 9057; Methyl (4-Aminophenylsulfonyl) carbamate; Methyl 4-Amino Benzene sulfonylcarbamate; Methyl p-Amino Benzene sulfonylcarbamate; N1-Methoxycarbonyl sulfanilamide ; Plakin. Grades: Highly Purified. CAS No. 3337-71-1. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Asunaprevir | Asunaprevir is a potent hepatitis C virus (HCV) non-structural protein protease inhibitor currently in Phase III clinical trials for the treatment of HCV infection. Uses: Protease inhibitors. Alternative Names: BMS-650032; BMS 650032; BMS650032; Asunaprevir. brand name: Sunvepra. Grades: >98%. CAS No. 630420-16-5. Molecular formula: C35H46ClN5O9S. Mole weight: 748.29. | |
| Asunaprevir | Asunaprevir (BMS-650032) is a potent and orally bioavailable hepatitis C virus (HCV) NS3 protease inhibitor, with IC50 of 0.2 nM-3.5 nM[1]. Asunaprevir inhibits SARS-CoV-2 3CLpro activity[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-650032. CAS No. 630420-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14434. | |
| Asundexian | Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY-2433334. CAS No. 2064121-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137431. | |
| Asunercept | Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein (hIgG1) targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APG101; CAN008. CAS No. 1450882-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99445. | |
| AsuNH I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑CTAGC CGATC↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Actinobacillus suis NH. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1029EN. | |
| Asvasiran sodium | Asvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALN-RSV01 sodium. CAS No. 1386946-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158824A. | |
| ASX-173 | ASX-173 is an orally active inhibitor of asparagine synthetase (ASNS) (IC50 = 0.113 μM, Ki = 0.4 nM). ASX-173 enhances the anticancer activity of L-asparaginase (ASNase) (HY-P1923). ASX-173 disrupts nucleotide synthesis and induces leukemia cell cycle arrest, apoptosis and autophagy in leukemia cells in combination with ASNase. ASX-173 slows the growth of OCI-AML2 xenografts in combination with ASNase. ASX-173 is indicated for the study of acute lymphoblastic leukemia, acute myeloid leukemia, colorectal cancer, and other cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748800-08-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175282. | |
| Asymmetric dimethylarginine | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine. CAS No. 30315-93-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113216. | |
| Asymmetric-dimethylarginine-d6 dihydrochloride | Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine-d6 dihydrochloride. CAS No. 1313730-20-9. Pack Sizes: 1 mg. Product ID: HY-113216BS. | |
| Asymmetric dimethylarginine (Standard) | Hesperetin (Standard) is the analytical standard of Hesperetin. This product is intended for research and analytical applications. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NG,NG-Dimethylarginine (Standard). CAS No. 30315-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113216R. | |
| Asymmetric Doubler (Lev) Phosphoramidite | Asymmetric Doubler (Lev) Phosphoramidite is a critical reagent used in the synthesis of nucleic acids with high efficiency and precision. It serves as a catalyst for the asymmetric doubling of chiral phosphoramidites, making it an essential tool for the production of oligonucleotides used in diagnostics and therapeutics for various diseases including cancer, viral infections and genetic disorders. Alternative Names: 1-[5-(4,4'-dimethoxytrityloxy)pentylamido]-3-[5-levulinyloxypentylamido]-propyl-2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C48H67N4O10P. Mole weight: 891.04. | |
| Aszonalenin | Aszonalenin is a nitrogen-containing heterocyclic antibiotic produced by Aspergillus zonatus. It can cause abnormal second division of sea urchin embryo. CAS No. 81797-27-5. Molecular formula: C23H23N3O2. Mole weight: 373.45. | |
| Aszonapyrone A | Aszonapyrone A is a lactone antibiotic produced by Aspergillus zonatus, which has anti-Staphylococcus aureus activity. CAS No. 83103-08-6. Molecular formula: C28H40O5. Mole weight: 456.61. | |
| AT 1 | AT 1 is a highly selective BRD4 protein degrader composed of a BET bromodomain inhibitor (+)-JQ1 conjugated to a von Hippel-Lindau (VHL) ligand. Alternative Names: BRD4 degrader AT1; (2S,4R)-1-((R)-2-acetamido-3-((6-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexyl)thio)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098836-45-2. Molecular formula: C48H58ClN9O5S3. Mole weight: 972.68. | |
| AT 1001 | AT 1001 is a partial agonist and antagonist of α3β4 nAChR ligand (Ki value 2.6?nM at α3β4 nAChR). In vivo AT-1001 potently blocks nicotine self-administration in dose manner. Alternative Names: AT 1001; AT1001; AT-1001. Grades: 99%. CAS No. 1314801-63-2. Molecular formula: C15H21BrN2. Mole weight: 309.24. | |
| AT 1001 | AT 1001 is an orally effective α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) antagonist with a Ki value of 2.64 nM. AT 1001 reversibly blocks Epibatidine (HY-101078)-induced inward currents in HEK cells transfected with α3β4 nAChR. AT 1001 dose-dependently blocks nicotine self-administration behavior in rats, alleviates gluten-induced gastrointestinal symptoms, blocks tight junction toxin-induced immune responses, and reduces the incidence of type 1 diabetes in rats. AT 1001 can be used in the research of nicotine addiction and celiac disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314801-63-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135783. | |
| AT 101 | AT 101. Group: Biochemicals. Grades: Purified. CAS No. 90141-22-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AT 1015 | AT 1015. Group: Biochemicals. Grades: Purified. CAS No. 190508-50-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AT-130 | AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 211364-06-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100028. | |
| AT13148 | AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Alternative Names: AT-13148; (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol. Grades: >98%. CAS No. 1056901-62-2. Molecular formula: C17H16ClN3O. Mole weight: 313.78. | |
| AT 2433 A1 | AT 2433 A1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Alternative Names: AT2433-A1; 6-Methyl-11-chloro-12-[6-O-[4-(methylamino)-2,4-dideoxy-alpha-L-threo-pentopyranosyl]-4-O-methyl-beta-D-glucopyranosyl]-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grades: >98%. CAS No. 102644-20-2. Molecular formula: C34H35ClN4O9. Mole weight: 679.11. | |
| AT 2433 A2 | AT 2433 A2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Alternative Names: AT 2433-A2; AT2433-A2. Grades: >98%. CAS No. 102644-19-9. Molecular formula: C33H33ClN4O9. Mole weight: 665.09. | |
| AT 2433 B1 | AT 2433 B1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Alternative Names: AT2433-B1. Grades: >98%. CAS No. 102622-96-8. Molecular formula: C34H36N4O9. Mole weight: 644.67. | |
| AT 2433 B2 | AT 2433 B2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Alternative Names: AT2433-B2; 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(4-amino-2,4-dideoxypentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydor-6-methyl-. Grades: >98%. CAS No. 102622-95-7. Molecular formula: C33H34N4O9. Mole weight: 630.64. | |
| AT-265 | AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Alternative Names: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. Grades: >98%. CAS No. 66522-52-9. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77. | |
| AT-406 | AT-406 is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3 (with Ki of 66.4 nM), cIAP1-BIR3(with Ki of 1.9 nM) and cIAP2-BIR3 (with Ki of 5.1 nM), respectively. Alternative Names: AT406; AT 406; SM-406; SM 406; SM406; ARRY-334543; ARRY 334543; ARRY334543. Grades: >98%. CAS No. 1071992-99-8. Molecular formula: C32H43N5O4. Mole weight: 561.71. | |
| AT 56 | AT 56. Group: Biochemicals. Grades: Purified. CAS No. 162640-98-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AT-56 | AT-56. Group: Biochemicals. Alternative Names: 4-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]-piperidine. Grades: Highly Purified. CAS No. 162640-98-4. Pack Sizes: 5mg. Molecular Formula: C25H27N5, Molecular Weight: 397.52. US Biological Life Sciences. | Worldwide |
| AT-56 | AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 162640-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13988. | |
| AT6 | AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4). Uses: Scientific research. Category: Signaling pathways. CAS No. 2098836-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112375. | |
| AT7519 | AT7519 (AT7519M) as a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT7519M. CAS No. 844442-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940. | |
| AT7519 HCl | AT-7519 is an orally bioavailable small molecule CDK inhibitor with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. Alternative Names: AT7519 HCl; AT 7519 HCl; AT-7519 HCl. CAS No. 902135-91-5. Molecular formula: C16H18Cl3N5O2. Mole weight: 418.71. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 857531-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12059. | |
| AT791 | AT791 is a potent and orally bioavailable TLR7 and TLR9 inhibitor. AT791 inhibits TLR7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219962-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124603. | |
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