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| Product | Description | |
|---|---|---|
| Arbutin | Arbutin. Synonyms: Hydroquinone-Beta-D-glucopyranoside. CAS No. 497-76-7. Product ID: CDC10-0032. Molecular formula: C12H16O7. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Arbutin; CDC10-0032; 497-76-7; C12H16O7; Hydroquinone-Beta-D-glucopyranoside; 207-850-3; MFCD00016915; 497-76-7. Purity: ≥98%. Color: White. EC Number: 207-850-3. Physical State: Powder. Solubility: H2O: 50 mg/mL hot, clear. Quality Level: 200. Storage: Inert atmosphere,Room Temperature. Application: Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Boiling Point: 375.31°C (rough estimate). Melting Point: 195 °C. Product Description: Arbutin is a derivative of hydroquinone used in skin-whitening ingredients. It is reported to inhibit the activity of tyrosinase, which is a key enzyme for melanin biosynthesis. This acts to effectively prevent the anomalous increase of melanin which is blamed for age or sun spots and freckles. |  |
| Arbutin | Arbutin is a glycosylated hydroquinone extracted from bearberry plant. Arbutin acts as an inhibitor of tyrosinase, and is used as a skin-lightening agent for the prevention of melanin formation in skin conditions. It is a good functional cosmetics material. Uses: Skin-lightening agent. Synonyms: 4-Hydroxyphenyl β-D-glucopyranoside; Hydroquinone-b-D-glucoside; Glucopyranoside, p-hydroxyphenyl, β-D-; Arbutine; Arbutoside; Arbutyne; Hydroquinone glucose; Hydroquinone β-D-glucopyranoside; NSC 4036; p-Arbutin; p-Hydroxyphenyl β-D-glucopyranoside; p-Hydroxyphenyl β-D-glucoside; Ursin; Uvasol; β-Arbutin. Grade: ≥98%. CAS No. 497-76-7. Molecular formula: C12H16O7. Mole weight: 272.25. |  |
| Arbutin | Arbutin. Group: Biochemicals. Alternative Names: 4-Hydroxyphenyl- β-D-glucopyranoside; Arbutine; Arbutoside; Arbutyne; Hydroquinone Glucose; Hydroquinone β-D-Glucopyranoside; NSC 4036; Ursin; Uvasol; p-Arbutin; p-Hydroxyphenyl β-D-Glucopyranoside; p-Hydroxyphenyl β-D-Glucoside; β-Arbutin. Grades: Highly Purified. CAS No. 497-76-7. Pack Sizes: 10g. US Biological Life Sciences. |  Worldwide |
| Arbutin-[13C6] | Arbutin-[13C6] is the labelled analogue of Arbutin, a glycosylated hydroquinone that can be extracted from bearberry plant. Arbutin is a known inhibitor of tyrosinase, which in turn prevents the formation of melanin. Arbutin is often used as a skin-lightening agent in cosmetic products. Synonyms: Arbutin-13C6; 4-Hydroxyphenyl-β-D-glucopyranoside-13C6; Arbutine-13C6; Arbutoside-13C6; Arbutyne-13C6; Hydroquinone Glucose-13C6; Hydroquinone β-D-Glucopyranoside-13C6; NSC 4036-13C6; Ursin-13C6; Uvasol-13C6; p-Arbutin-13C6; p-Hydroxyphenyl β-D-Glucopyranoside-13C6; p-Hydroxyphenyl β-D-Glucoside-13C6; β-Arbutin-13C6. Grade: >95%. Molecular formula: C6[13C]6H16O7. Mole weight: 278.21. | |
| Arbutin > 99% HPLC | Arbutin > 99% HPLC. |  CA, FL & NJ |
| Arbutin monoester | Arbutin monoester. CAS No. 159946-47-1. Purity: 96%. Product ID: ACM159946471. Molecular formula: C28H46O8. Mole weight: 510.66. IUPAC Name: 4-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]quinoline. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| AR-C 102222 | AR-C 102222 has been found to be an iNOS inhibitor and show antinociceptive and anti-inflammatory activity in rodent pain models. Synonyms: AR-C 102222; AR C 102222; ARC 102222; ARC102222; 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride. Grade: ≥98% by HPLC. CAS No. 253771-21-0. Molecular formula: C19H16F2N6O.HCl. Mole weight: 418.83. | |
| AR-C102222 hydrochloride | AR-C102222 is a potent, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. Synonyms: 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile Hydrochloride (1:1). Grade: ≥98%. CAS No. 1781934-50-6. Molecular formula: C19H17ClF2N6O. Mole weight: 418.83. | |
| AR-C117977 | AR-C117977 is a potent MCT1 inhibitor that inhibited the rat MLR and was more potent than cyclosporin A (CsA). AR-C117977 can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. Synonyms: 5-((3-hydroxypropyl)thio)-1-isobutyl-3-methyl-6-(naphthalen-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C-117977; AR-C 117977. Grade: >98%. CAS No. 216685-07-3. Molecular formula: C25H28N2O3S2. Mole weight: 468.63. | |
| AR-C118925XX | AR-C118925XX is a selective P2Y2 receptor antagonist. AR-C118925XX inhibits ATP-induced IL-6 production and phosphorylation of p38. AR-C118925XX also inhibits Bleomycin (HY-108345)-induced dermal fibrosis in mice. AR-C118925XX also inhibits ATP-induced tumor growth[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 216657-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110126. |  |
| AR-C 118925XX | AR-C126313, a thiouracil derivative, has been found to be a competitive P2Y2 receptor antagonist and could inhibit P2Y2 receptor-induced β-arrestin translocation in vitro. Synonyms: AR-C126313; ARC126313; AR C126313; 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide. Grade: ≥97% by HPLC. CAS No. 216657-60-2. Molecular formula: C28H23N7O3S. Mole weight: 537.59. | |
| AR-C 118925XX | AR-C 118925XX. Group: Biochemicals. Grades: Purified. CAS No. 216657-60-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AR-C124910XX-N-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C124910XX-O-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C141990 hydrochloride | AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pKi values of 7.6, 6.6 for MCT-1 and MCT-2, respectively. Synonyms: AR-C 141990 hydrochloride. CAS No. 2250019-94-2. Molecular formula: C26H29ClN4O4S. Mole weight: 529.05. | |
| AR-C155858 | AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with Kis of 2.3 nM and 10 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 496791-37-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13248. | |
| AR-C155858 | AR-C155858. Group: Biochemicals. Alternative Names: (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-4-isoxazolidinol;(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C 155858. Grades: Highly Purified. CAS No. 496791-37-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AR-C155858 | AR-C155858 is a novel inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2, but exhibits no activity at MCT4. It can be used to probe MCTs' roles in the metabolic studies. Besides, AR-C155858 was found to have immunosuppressive activity and can inhibit the proliferation of T-lymphocytes. Synonyms: ARC155858; AR-C155858; ARC 155858. Grade: >98%. CAS No. 496791-37-8. Molecular formula: C21H27N5O5S. Mole weight: 461.53. | |
| ARC 239 | ARC239 dihydrochloride is a potent and selective α2 B adrenoceptor antagonist. It is used as an α-adrenoceptor blocking drug. It competitively antagonizes pressor responses to adrenaline and inhibits pressor responses to noradrenaline, tyramine, phenylephrine and dimethylphenylpiperazinium. Uses: Arc239 dihydrochloride is used as an α-adrenoceptor blocking drug. Synonyms: ARC239 dihydrochloride; ARC 239 dihydrochloride; ARC-239 dihydrochloride; 2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride; AR-C239 Dihydrochloride. Grade: 98%. CAS No. 67339-62-2. Molecular formula: C24H29N3O3. Mole weight: 407.5. | |
| ARC 239 dihydrochloride | The hydrochloride salt form of ARC 239, which has been found to be an α2B adrenoceptor antagonist as well as a norepinephrine-serotonin reuptake inhibitor. Uses: Adrenergic alpha-antagonists. Synonyms: ARC 239 dihydrochloride; ARC239 dihydrochloride; ARC-239 dihydrochloride; 2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride. Grade: ≥98% by HPLC. CAS No. 55974-42-0. Molecular formula: C24H29N3O3.2HCl. Mole weight: 480.43. | |
| AR-C 66096 tetrasodium salt | The sodium salt form of AR-C 66096, which has been found to be a P2Y12 receptor antagonist and could be probably used as an antithrombotic agent. Synonyms: ARL-66096; ARL 66096; ARL66096; 2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt. Grade: ≥98% by HPLC. CAS No. 145782-74-7. Molecular formula: C14H18F2N5Na4O12P3S. Mole weight: 703.26. | |
| ARCA ammonium salt | m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Synonyms: ARCA Ammonium; Anti Reverse Cap Analog ammonium salt; m7(3'-O-methy)G(5')ppp(5')G ammonium salt; 3'-O-Me-m7G(5')ppp(5')G ammonium salt; m27, 3'-OGP3G (ARCA Cap Analog) ammonium salt; 3'-O-Methyl-m7GpppG ammonium salt; ARCA (anti-reverse cap analog) ammonium salt; m27,3'OGpppG ammonium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine ammonium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| Arcaine sulfate | Arcaine sulfate is the sulfate salt of arcaine, which is a potent, competitive and novel antagonist of the polyamine site on the NMDA receptor. Synonyms: N,N'-1,4-Butanediylbisguanidine sulfate; 1,4-Diguanidinobutane sulfate salt. Grade: ≥99% by HPLC. CAS No. 14923-17-2. Molecular formula: C6H18N6SO4. Mole weight: 270.31. | |
| Arcaine sulfate | Arcaine sulfate. CAS No. 14923-17-2. Purity: >99 %. Product ID: ACM14923172. Molecular formula: C6H18N6O4S. Mole weight: 270.31. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arcaine (sulfate) | Arcaine (sulfate). Alternative Names: N,N'''-1,4-butanediylbis-guanidine, monosulfate. CAS No. 14923-17-2. Product ID: FFC-AR-14923172. Molecular formula: C6H16N6 · H2SO4. Mole weight: 270.3. IUPAC Name: 2-[4-(diaminomethylideneamino)butyl]guanidine;sulfuric acid. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arcaine Sulfate | Arcaine Sulfate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| ARCA Sodium | ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions. Synonyms: ARCA, sodium salt; Anti Reverse Cap Analog sodium salt; m7(3'-O-methy)G(5')ppp(5')G sodium salt; 3'-O-Me-m7G(5')ppp(5')G sodium salt; m27, 3'-OGP3G (ARCA Cap Analog) sodium salt; 3'-O-Methyl-m7GpppG sodium salt; ARCA (anti-reverse cap analog) sodium salt; m27,3'OGpppG sodium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine, sodium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grade: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| ARCC-4 | ARCC-4 is a low-nanomolar Androgen Receptor (AR) degrader based on PROTAC, with a DC50 of 5?nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1973403-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130492. | |
| archaeosine | Archaeosine, an essential compound, holds immense significance in the realm of biomedicine due to its potential therapeutic efficacy in a diverse array of ailments. A pivotal player in crafting targeted medications for cancer, neurological maladies, and infectious conditions, this product assumes a critical role in the advanced pharmaceutical landscape. Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-b-D-ribofuranosyl-; 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide. CAS No. 148608-52-0. Molecular formula: C12H16N6O5. Mole weight: 324.3. | |
| archaeosine synthase | In Euryarchaeota the reaction is catalysed by ArcS. In Crenarchaeota, which do not have an ArcS homologue, the reaction is catalysed either by a homologue of EC 6.3.4.20, 7-cyano-7-deazaguanine synthase that includes a glutaminase domain (cf. EC 3.5.1.2), or by a homologue of EC 1.7.1.13, preQ1 synthase. The enzyme from the Euryarchaeon Methanocaldococcus jannaschii can also use arginine and ammonium as amino donors. Group: Enzymes. Synonyms: ArcS; TgtA2; MJ1022 (gene name); glutamine:preQ0-tRNA amidinotransferase (incorrect). Enzyme Commission Number: EC 2.6.1.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2938; archaeosine synthase; EC 2.6.1.97; ArcS; TgtA2; MJ1022 (gene name); glutamine:preQ0-tRNA amidinotransferase (incorrect). Cat No: EXWM-2938. |  |
| archaetidylinositol phosphate synthase | Requires Mg2+ or Mn2+ for activity. The enzyme is involved in biosynthesis of archaetidyl-myo-inositol, a compound essential for glycolipid biosynthesis in archaea. Group: Enzymes. Synonyms: AIP synthase. Enzyme Commission Number: EC 2.7.8.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3338; archaetidylinositol phosphate synthase; EC 2.7.8.39; AIP synthase. Cat No: EXWM-3338. | |
| archaetidylserine synthase | Requires Mn2+. Isolated from the archaeon Methanothermobacter thermautotrophicus. Group: Enzymes. Enzyme Commission Number: EC 2.7.8.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3337; archaetidylserine synthase; EC 2.7.8.38. Cat No: EXWM-3337. | |
| Archidonic acid,4,5-dimethoxy-1-(2-nitrophenyl)ethyl ester | Archidonic acid,4,5-dimethoxy-1-(2-nitrophenyl)ethyl ester. Alternative Names: ARACHIDONIC ACID 1-(4,5-DIMETHOXY-2-NITROPHENYL)ETHYL ESTER;arachidonic acid 1-(4,5-dimethoxy-2-*nitrophenyl);ARACHIDONIC ACID 1-(4,5-DIMETHOXY-2-NITR OPHENYL)ET;arachidonic acid 1-(4,5-dimethoxy-2-nitrophenyl)ethyl este;1-(4,5-Dimethoxy-2-nitrophenyl)et. CAS No. 155613-96-0. Product ID: ACM155613960-1. Molecular formula: C30H43NO6. Mole weight: 513.67. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arcitumomab | Arcitumomab is a humanized monoclonal antibody raised against human carcinoembryonic antigen (CEA). Arcitumomab is used as a diagnostic imaging agent for colorectal cancers. Synonyms: IMMU 4; CEA-Scan; Immunoglobulin G1, anti-(human carcinoembryonic antigen) Fab' fragment (mouse monoclonal IMMU-4 γ1-chain), disulfide with mouse monoclonal IMMU-4 light chain. Grade: 95%. CAS No. 154361-48-5. | |
| Arcotatug | Arcotatug (IBI-343 antibody) is a CLDN18.2 targeting humanized monoclonal antibody. Arcotatug can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IBI-343 antibody; HB37A6; TAK-921 Antibody. CAS No. 3031170-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991564. | |
| Arctigenin | Arctigenin. Group: Biochemicals. Grades: Purified. CAS No. 7770-78-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Arctigenin | Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Arctigenin. CAS No. 7770-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-N0035. | |
| Arctiin | Arctiin. Group: Biochemicals. Grades: Plant Grade. CAS No. 20362-31-6. Pack Sizes: 20mg. Molecular Formula: C27H34O11, Molecular Weight: 534.55. US Biological Life Sciences. | Worldwide |
| Arctiin | Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in ammatory cytokines levels. Arctiin can used in study glomerulonephritis[4][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Arctii; NSC 315527; Arctigenin-4-glucoside. CAS No. 20362-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N0034. | |
| Arcyriaflavin A | Arcyriaflavin A is a potent dual target agent of calcium/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 4 (CDK4). Its IC50 values are 140 nM and 25 nM for CDK4 and CaMKII respectively, which is selective over protein kinase A (PKA) and PKC in vitro. It inhibits proliferation of HCT116 and NCI H460 human carcinoma cells and replication of human cytomegalovirus (HCMV) in vitro. It also inhibits proliferation and induces apoptosis of endometriotic cyst stromal cells (ECSCs). Synonyms: Arcyriaflavin A; Arcyriaflavin-A; 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; Maleimide Indolocarbazole. Grade: ≥98% by HPLC. CAS No. 118458-54-1. Molecular formula: C20H11N3O2. Mole weight: 325.32. | |
| ARD1 | ARD1 is isolated from Archaeoprepona demophoon. It possesses potent anti-fungal activity. | |
| ARD-1676 | ARD-1676 is an orally available androgen receptor (AR) PROTAC degrader, consisting of AR ligand and cereblon ligand. ARD-1676 has AR-degrading activity in vitro and in vivo and inhibits VCaP tumor growth in mouse xenograft tumor models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2632305-36-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156111. | |
| ARD-2051 | ARD-2051 is a selective and orally active androgen receptor (AR) proteolysis-targeting chimera degrader. ARD-2051 achieves DC50 values of 0.6 nM for AR protein degradation in both the LNCaP and VCaP prostate cancer cell lines. ARD-2051 exhibits effective anti-tumor activity in VCaP xenograft mice model. ARD-2051 can be used for the research of prostate cancer (Pink: AR ligand (HY-400666), Blue: CRBN Ligand (HY-14658), Black: Linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2632305-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149862. | |
| ARD-2128 | ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor degrader. It effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. Synonyms: ARD2128; ARD 2128; N-[(1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperidin-4-yl]methyl]piperazin-1-yl]benzamide. Grade: ≥98%. CAS No. 2222111-87-5. Molecular formula: C45H50ClN7O6. Mole weight: 820.37. | |
| ARD-2128 | ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222111-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132292. | |
| ARD-2585 | ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer. Synonyms: Benzamide, N-[trans-4-[(3-chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]-; N-((1r,4r)-4-((3-chloro-4-cyanophenyl)(methyl)amino)cyclohexyl)-4-(4-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)azetidin-3-yl)piperazin-1-yl)benzamide; N-[trans-4-[(3-Chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]benzamide; ARD 2585; ARD2585. CAS No. 2757422-79-8. Molecular formula: C41H43ClN8O5. Mole weight: 763.28. | |
| ARD-2585 | ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2757422-79-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139436. | |
| ARD-266 | ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s = 0.2-1 nM). Synonyms: 2-Pyrrolidinecarboxamide, N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-, (2S,4R)-; (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)ethynyl)piperidin-1-yl)-3-oxo-1-phenylpropyl)-4-hydroxy-1-((R)-3-methyl-2-(3-methylisoxazol-5-yl)butanoyl)pyrrolidine-2-carboxamide; (2S,4R)-N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-2-pyrrolidinecarboxamide. Grade: ≥95%. CAS No. 2666951-70-6. Molecular formula: C52H59ClN6O7. Mole weight: 915.51. | |
| ARD-61 | ARD-61 is a highly potent, effective and specific PROTAC androgen receptor (AR) degrader. ARD-61 potently and effectively induces AR and progesterone receptors (PR) degradation in AR+ cancer cell lines. ARD-61 induces apoptosis and effectively induces tumor growth inhibition in the MDA-MB-453 xenograft model in mice[1]. ARD-61 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2316837-08-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-139659. | |
| ARD-69 | ARD-69 is a PROTAC degrader based on the E3 ubiquitin ligase VHL and targeting the androgen receptor, which can induce androgen receptor (AR) protein degradation in AR-positive prostate cancer cells. ARD-69 inhibits AR-regulated gene expression, binds to the AR ligand binding domain at one end and binds to VHL at the other end, prompting AR to be recruited to the E3 ubiquitin ligase complex, triggering proteasome degradation, thereby inhibiting AR signaling pathways and downstream gene expression (such as PSA, TMPRSS2). ARD-69 can be used to study of castration-resistant prostate cancer (mCRPC)[1][2][3].ARD-69 is composed of a target protein ligand (pink part) AR antagonist 14 (HY-172624), a PROTAC linker (black part) tert-Butyl 4-ethynyl-[1,4'-bipiperidine]-1'-carboxylate (HY-W442074), and a VHL-type E3 ubiquitinase ligand (blue part) VH 101, acid (HY-47070); among them, the VHL ligand and the linker can form a conjugate VH 101-amide-piperidine-Pip-alkyne (HY-172625). Uses: Scientific research. Category: Signaling pathways. CAS No. 2316837-10-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114402. | |
| Ardeemin | Ardeemin is a heterocyclic compound produced by Aspergillus fischeri var. brasiliensis AB 1826 M-35. Aldamide has no antibacterial activity and has no effect on multidrug-resistant (MDR) tumor cells, but its acetylated compound 5-N-acetylaldamide can improve its effect on multidrug-resistant tumor cells. Molecular formula: C26H26N4O2. Mole weight: 426.51. | |
| Ardisiacrispin A | Ardisiacrispin A. Group: Biochemicals. Alternative Names: Saxifragifolin B; Deglucocyclamin I. Grades: Plant Grade. CAS No. 23643-61-0. Pack Sizes: 20mg. Molecular Formula: C52H84O22, Molecular Weight: 1061.21. US Biological Life Sciences. | Worldwide |
| Ardisiacrispin B | Ardisiacrispin B displays cytotoxic effects in multi-factorial agent resistant cancer cells via ferroptotic and apoptotic cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112766-96-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8198. | |
| Arecaidine | A metabolite of Arecoline, a cholinergic agonist. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid; 1,2,5,6-Tetrahydro-1-methyl-nicotinic Acid; Arecaine; N-Methylguvacine; NSC 76017. Grades: Highly Purified. CAS No. 499-04-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Arecaidine | Arecaidine is a GABA transport system inhibitor. Arecaidine inhibits the proliferation of oral mucosal fibroblasts, increases the secretion of IL-6, TGF-β and TNF-α in cells, downregulates the expression of PPAR-γ and PCK1 in cells, and upregulates the expression of TGF-β1. Arecaidine inhibits the uptake of γ-aminobutyric acid and β-alanine by the central nervous system of cats. Arecaidine inhibits hPAT1-mediated L-[3H]proline uptake in cells. Arecaidine can be used in research related to neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 499-04-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-N2368. | |
| Arecaidine-d5 Hydrobromide | A labeled metabolite of Arecoline, a cholinergic agonist. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid-d5 Hydrobromide; 1,2,5,6-Tetrahydro-1-methylnicotinic Acid-d5 Hydrobromide; Arecaine-d5 Hydrobromide; N-Methylguvacine-d5 Hydrobromide; NSC 76017-d5 Hydrobromide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Arecaidine Ethyl Ester Hydrochloride | A Arecaidine derivative as muscarinic acetylcholine receptor binding. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Ethyl Ester Hydrochloride; 1,2,5,6-Tetrahydro-1-methylnicotinic Acid Ethyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 17210-50-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Arecaidine Ethyl Ester Hydrochloride | Arecaidine Ethyl Ester Hydrochloride. Alternative Names: 3-PYRIDINECARBOXYLIC ACID 1,2,5,6-TETRAHYDRO-1-METHYL ETHYL ESTER MONOHYDROCHLORIDE, 17210-50-3, Arecaidine Ethyl Ester Hydrochloride, 1,2,5,6-Tetrahydro-1-methylnicotinic Acid Ethyl Ester Hydrochloride, 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Ethyl Ester Hydrochloride. CAS No. 17210-50-3. Purity: 96%. Product ID: ACM17210503. Molecular formula: C9H16ClNO2. Mole weight: 205.68. IUPAC Name: ethyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arecaidine hydrochloride | Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6018-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2368A. | |
| Arecaidine propargyl ester hydrobromide | Arecaidine propargyl ester hydrobromide is an agonist of M2 muscarinic acetylcholine receptors and has the activity of inhibiting tumor cell proliferation. The application of arecaidine propargyl ester hydrobromide has shown that it can reduce the number of ovarian cancer cells in vitro and induce apoptosis and the production of reactive oxygen species (ROS) at specific concentrations. Arecaidine propargyl ester hydrobromide can also arrest cells at the G2/M phase of the cell cycle and increase the percentage of abnormal mitosis. Arecaidine propargyl ester hydrobromide is more sensitizing to ovarian surface epithelial cells with higher M2 receptor levels than to cancer cells. Arecaidine propargyl ester hydrobromide exhibits the effect of lowering arterial blood pressure when interacting with the cardiovascular system in a natural physiological state, indicating its potential pharmacological application[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 116511-28-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-134061. | |
| Arecaidine propargyl ester hydrobromide(ape) | Arecaidine propargyl ester hydrobromide(ape). Alternative Names: A140_SIGMA, Arecaidine propargyl ester hydrobromide, MLS002153370, MolPort-003-940-050, CID189406, EU-0100136, NCGC00093626-01, SMR000326890, A-140, APE, 1-Methyl-1,2,5,6-tetrahydro-3-pyridine carboxylic acid propargyl ester hydrobromide, 116511-28-5. CAS No. 116511-28-5. Purity: 96%. Product ID: ACM116511285. Molecular formula: C10H13NO2??·HBr. Mole weight: 260.13. IUPAC Name: prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate hydrobromide. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arecaidine propargyl ester tosylate | Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist. It displays some selectivity for cardiac versus ileal M2 receptors. Synonyms: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate. CAS No. 147202-94-6. Molecular formula: C17H21NO5S. Mole weight: 351.42. | |
| Arecaidine propargyl ester tosylate | Arecaidine propargyl ester tosylate. CAS No. 147202-94-6. Product ID: ACM147202946. Molecular formula: C10H13NO2S.C7H8SO3. Mole weight: 351.42. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Arecoline | Arecoline, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-N2364. | |
| Arecoline hydrobromide | Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide. CAS No. 300-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0489. | |
| Arecoline hydrobromide | 25g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C8H13NO2 · HBr. CAS No. 300-08-3. Prepack ID 11161105-25g. Molecular Weight 236.11. See USA prepack pricing. |  |
| Arecoline Hydrobromide | A cholinergic alkaloid from seeds of the betel nut palm Areca catechu. Anthelmintic (Cestodes); cathartic. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Methyl Ester Hydrobromide;1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic Acid Methyl Ester Hydrobromide; Arecaidine Methyl Ester Hydrobromide; Arecolin Hydrobromide; Methylarecaidine Hydrobromide. Grades: Highly Purified. CAS No. 300-08-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Arenicin-1 | Arenicin-1 is an antimicrobial peptide that can be isolated from coelomocytes of the marine polychaeta lugworm Arenicola marina. Arenicin-1 displays potent antimicrobial activity, with MIC values ranging from 2.0 to 8.0 μM. Arenicin-1 can be used for antibacterial research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 808102-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11190. | |
| Arenobufagin | Arenobufagin. Group: Biochemicals. Alternative Names: Arenobufogenin. Grades: Plant Grade. CAS No. 464-74-4. Pack Sizes: 10mg. Molecular Formula: C24H32O6, Molecular Weight: 416.507. US Biological Life Sciences. | Worldwide |
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