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Aprepitant Impurity 8 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: Fosaprepitant Morpholine Hydrochloride; (2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride. CAS No. 1333998-27-8. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81.
Aprepitant impurity A
Aprepitant impurity A is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2. Mole weight: 527.47.
Aprepitant Impurity A Enantiomer
Aprepitant Impurity A Enantiomer is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2. Mole weight: 527.47.
Aprepitant Impurity B Enantiomer HCl
A metabolite of Aprepitant. Synonyms: (2R,3S)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grades: > 95%. CAS No. 183901-47-5. Molecular formula: C27H24F7NO2. HCl. Mole weight: 527.49 36.46.
Aprepitant Impurity B HCl
Aprepitant Impurity B HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2.HCl. Mole weight: 563.93.
Aprepitant-M3 Metabolite
Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
Aprepitant N-Oxide
Aprepitant N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00838. Format: Neat.
Aprepitant Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Aprepitant Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Apricot Kernel Oil
Light carrier oil made from the dried kernels of apricots. Has similar properties as almond oil. 100% pure. Rich in vitamin A & E and oleic & linoleic fatty acids. SAP Value: 180-200. Uses: Creams, lotions, makeup, face oils, color cosmetics, conditioners, skin treatments, hand creams. Additional or Alternative Names: PERSIC OIL;APRICOT KERNEL OIL;FEMA 2150;Oils,apricot;PRUNUS ARMENIACA (APRICOT) KERNEL OIL;Prunusarmeniacakerneloil,refined;APRICOT(PRUNUSARMENIACA)KERNELOIL;PERSICOILREFINED. Product Category: Heterocyclic Organic Compound. Appearance: Clear light yellow liquid, cold pressed, refined, characteristic mild odor. CAS No. 72869-69-3. Molecular formula: CAS: 72869-69-3. Product ID: ACM72869693. Alfa Chemistry ISO 9001:2015 Certified.
Apricoxib
Apricoxib. Group: Biochemicals. Alternative Names: 4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide; 4-Methyl-2- (4-ethoxyphenyl) -1- (4-sulfamoylphenyl) pyrrole; CS 706; R 109339; TG 01. Grades: Highly Purified. CAS No. 197904-84-0. Pack Sizes: 10mg. Molecular Formula: C19H20N2O3S, Molecular Weight: 356.44. US Biological Life Sciences.
Worldwide
Apricoxib
Apricoxib is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. Synonyms: CS-701; CS 701; CS701; TG01; TG 01; TG-01; R-109339, R 109339; R109339; Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-. CAS No. 197904-84-0. Molecular formula: C19H20N2O3S. Mole weight: 356.44.
Apricoxib-d4
Apricoxib-d4. Group: Biochemicals. Alternative Names: 4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide-d4; 4-Methyl-2- (4-ethoxyphenyl) -1- (4-sulfamoylphenyl) pyrrole-d4; CS 706-d4; R 109339-d4; TG 01-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H16D4N2O3S, Molecular Weight: 360.46. US Biological Life Sciences.
APRIL (a proliferation-inducing ligand), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. APRIL protein (CD256) can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein has been widely used in the study of lymphatic malignancies. Synonyms: A Proliferating-inducing Ligand; TNFSF13; TRDL-1a; APRIL/TNFSF13 Protein, Mouse; rMuApril/TNFSF13; TNFSF 13; TNFSF-13; CD256. Grades: ≥98% by HPLC. Mole weight: ~21.9 kDa.
APRIL from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
APRIL human
recombinant, expressed in Hi-5 Insect cells, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
APRIL human
APRIL (a proliferation-inducing ligand), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. APRIL protein (CD256) can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein has been widely used in the study of lymphatic malignancies. Synonyms: A Proliferating-inducing Ligand; TNFSF13; TRDL-1a; APRIL/TNFSF13 Protein, Mouse; rMuApril/TNFSF13; TNFSF 13; TNFSF-13; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2. Grades: ≥95% by HPLC. Mole weight: ~16.3 kDa.
Aprindine is a Class 1b antiarrhythmic agent as a cardiac depressant used in arrhythmias. Uses: A cardiac depressant used in arrhythmias. Synonyms: N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine. Grades: ≥98%. CAS No. 37640-71-4. Molecular formula: C22H30N2. Mole weight: 322.48.
Aprindine
Aprindine is an arrhythmia inhibitor that stabilizes the cell membranes of heart muscle cells, thereby preventing abnormal electrical impulses from causing irregular heartbeats. In hematological toxicity studies, aprindine showed potential inhibitory effects on the replicative capacity of mouse and human blood cells at certain concentrations [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37640-71-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0236.
Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research. Uses: Scientific research. Group: Signaling pathways. CAS No. 33237-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0236A.
Aprindine Hydrochloride
Class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given orally. Group: Biochemicals. Alternative Names: N1-(2,3-Dihydro-1H-inden-2-yl)-N3,N3-diethyl-N1-phenyl-1,3-propanediamine Hydrochloride; N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propanediamine; Amidonal; Aspenon; Compd 83846; Fibocil; Fiboran; MS 5075; NSC 284614; Ritmusin. Grades: Highly Purified. CAS No. 33237-74-0. Pack Sizes: 50mg. Molecular Formula: C??H??ClN?, Molecular Weight: 358.95. US Biological Life Sciences.
Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC 50 s of 3.4 nM and 987 nM, and pA 2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-132577. CAS No. 1103522-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15895.
a-Prodine hydrochloride
a-Prodine hydrochloride. Group: Biochemicals. Alternative Names: (3R,4S)-rel-1,3-dimethyl-4-phenyl-4-piperidinol 4-propanoate hydrochloride; cis-(±)-1,3-Dimethyl-4-phenyl-4-piperidinol propanoate hydrochloride; (±)-Alphaprodine hydrochloride. Grades: Highly Purified. CAS No. 561-78-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H24ClNO2. US Biological Life Sciences.
Worldwide
Apronal
Apronal (Allylisopropylacetylurea, Apronalide) can bu used for the research of neuropsychiatry disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Allylisopropylacetylurea; Apronalide. CAS No. 528-92-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2177.
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C284H432N84O79S7. CAS No. 9087-70-1. Prepack ID 16927557-25mg. Molecular Weight 6511.45. See USA prepack pricing.
Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with K i s of 0.06 pM and 9 nM, respectively. Uses: Scientific research. Group: Peptides. CAS No. 9087-70-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0017.
Aprotinin, Bovine (Pancreatic trypsin inhibitor)
Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes, dissociating at pH >10 or <3. Effective concentration is equimolar with protease. Group: Biochemicals. Alternative Names: Antikrein; Antilysin; Antilysine; Aprostat; Aprotinin; BPTI; BPTI Trypsin Inhibitor; Basic Pancreatic Trypsin Inhibitor; Bayer A 128; Bovine Basic Pancreatic Trypsin Inhibitor; Bovine Pancreatic Trypsin Inhibitor; Bovine Trypsin Inhibitor; Fosten; Kallikrein-trypsin Inactivator; Kiker 52G; Kir Richter; Kunitz Pancreatic Trypsin Inhibitor; Kunitz Protease Inhibitor; Kunitz Trypsin Inhibitor; Kunitz-type Inhibitor; Kunitz-type Proteinase Inhibitor; Kunitz-type Trypsin Inhibitor; Onquinin; Pancreatic Basic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor (Kunitz); Protease Inhibitor, Kunitz Type; RP 9921; Repulson; Trasuylol; Trasylol; Trazinin; Triazinin; Trypsin Inhibitor, Trasylol; Trypsin-kallikrein Inhibitor (Kunitz); Zymofren. Grades: Highly Purified. CAS No. 9087-70-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C???H???N??O??S?, Molecular Weight: 6511.45. US Biological Life Sciences.
Worldwide
Aprutumab
Aprutumab is a humanized monoclonal antibody directed against FGFR2. Aprutumab has been used in the research of solid tumors. Synonyms: BAY 1179470; BAY-1179470; BAY1179470. CAS No. 1634620-63-5.
APS
APS is an active sulfate ester of 5'-AMP, which is used in pyrosequencing and bioluminescence applications. Synonyms: Adenosine- 5'- O- phosphosulfate, sodium salt. Grades: guaranteed purity ≥ 95% by HPLC, usual purity ≥ 98%. CAS No. 102029-95-8. Molecular formula: C10H14N5O10PS (free acid). Mole weight: 427.3 (free acid).
APS-2-79
APS-2-79 is a small molecule antagonist of MEK phosphorylation by RAF through direct binding of the KSR active site, and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2). Synonyms: 6,7-Dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine; APS-2-79; APS 2-79; APS2-79; APS-279; APS 279; APS279. CAS No. 2002381-25-9. Molecular formula: C23H21N3O3. Mole weight: 387.43.
APS-2-79 HCl
APS-2-79 is a MAPK antagonist which can modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization and the conformational changes required for phosphorylation and activation of KSR-bound MEK. APS-2-79 was found to bind to the KSR active site with an IC50 value of 120 nM, antagonizing MEK (MAPKK) phosphorylation by RAF. Synonyms: APS-2-79 HCl; APS2-79 HCl; APS 2-79 HCl; APS-279 HCl; APS279 HCl; APS 279 HCl; SCHEMBL18153640; AKOS032944984; CS-6151; 6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine;hydrochloride. Grades: 99.26 %. CAS No. 2002381-31-7. Molecular formula: C23H21N3O3.HCl. Mole weight: 423.89.
APS-5 is a chemiluminescent substrate based on 9, 10-dihydroacridine, which is mainly used for ELISA detection of alkaline phosphatase AP conjugated compounds and for the diagnosis of immune detection, such as tumor markers, infectious diseases, endocrine function, hormones, etc. Synonyms: Methanol, [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)-, 1-(dihydrogen phosphate), disodium salt (1:2); Methanol, [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)-, dihydrogen phosphate (ester), disodium salt; Lumigen APS 5; Sodium ((4-chlorophenyl)thio)(10-methylacridin-9(10H)-ylidene)methyl phosphate; [(4-chlorophenyl)thio](10-methyl-9(10H)-acridinylidene)methanol 1-(dihydrogen phosphate) disodium salt; [[(4-chlorophenyl)thio]-(10-methyl-9-acridinylidene)methyl] phosphate disodium salt. Grades: ≥99% by HPLC. CAS No. 193884-53-6. Molecular formula: C21H15ClNNa2O4PS. Mole weight: 489.82.
APTAB
APTAB is a fluorescent cationic membrane probe whose location of anthracene-labeled molecules incorporated into model membranes was measured by fluorescence quenching. Synonyms: 3-(9-Anthracene)propyl trimethylammonium bromide. CAS No. 86727-71-1. Molecular formula: C20H24BrN. Mole weight: 358.32.
Aptazapine
Aptazapine is a tetracyclic antidepressant. It was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. Aptazapine is a α2-adrenergic receptor antagonist. It is also a 5-HT2 receptor antagonist and H1 receptor inverse agonist, while having no significant effects on the reuptake of serotonin or norepinephrine. Uses: Antidepressant. Synonyms: CGS 7525 A;2-methyl-1,3,4,14b-tetrahydro-2H,10H-benzo[e]pyrazino[2,1-c]pyrrolo[1,2-a][1,4]diazepine; 71576-41-5 (maleate). Grades: 98%. CAS No. 71576-40-4. Molecular formula: C16H19N3. Mole weight: 253.35.
Aptazapine maleate
Aptazapine is a tetracyclic antidepressant. It was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. Aptazapine is a α2-adrenergic receptor antagonist. It is also a 5-HT2 receptor antagonist and H1 receptor inverse agonist, while having no significant effects on the reuptake of serotonin or norepinephrine. Uses: Antidepressant. Synonyms: (+-)-1,3,4,14b-Tetrahydro-2-methyl-2H,10H-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)benzodiazepine maleate (1:1). Grades: 98%. CAS No. 71576-41-5. Molecular formula: C16H19N3.C4H4O4. Mole weight: 369.42.
Aptiganel hydrochloride
Aptiganel hydrochloride (Cerestat) is a non-competitive NMDA receptor antagonist with neuroprotective effect. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CNS 1102. CAS No. 137160-11-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110097.
APTO-253 (LOR253 HCl)
Cas No. 1422731-37-0.
APTRA trimethyl ester
APTRA trimethyl ester is a building block for the synthesis of fluorescent indicators. Synonyms: 2-(Carbomethoxy)-methoxy-N,N-bis((carbomethoxy)methyl)aniline. CAS No. 450358-62-0. Molecular formula: C15H19NO7. Mole weight: 325.31.
APTS
APTS. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Aminopyrene-1,3,6-trisulfonicacid,trisodiumsalt. Product Category: Other Fluorophores. Appearance: Yellow solid. CAS No. 196504-57-1. Molecular formula: C16H8N3O9S3. Mole weight: 523.4. Purity: 95%+. IUPACName: Trisodium;8-aminopyrene-1,3,6-trisulfonate. Canonical SMILES: C1=CC2=C3C(=C(C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])C=CC4=C(C=C(C1=C43)N)S(=O)(=O)[O-].[Na+].[Na+].[Na+]. Product ID: ACM196504571-1. Alfa Chemistry ISO 9001:2015 Certified.
APTS@ Fe2O3 Nanoparticles
APTS@ Fe2O3 Nanoparticles. Group: Nanopowders. CAS No. 1317-61-9.
APTSTAT3-9R
APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating motif. STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. The treatment of APTSTAT3-9R in various types of cancer cells blocks STAT3 phosphorylation and reduces expression of STAT targets. Treatment of various types of cancer cells with APTSTAT3-9R blocked STAT3 phosphorylation and reduced expression of STAT targets, including cyclin D1, Bcl-xL, and survivin. As a result, APTSTAT3-9R suppressed the viability and proliferation of cancer cells. Furthermore, intratumoral injection of APTSTAT3-9R exerted potent antitumor activity in both xenograft and allograft tumor models. Synonyms: H-DL-His-Gly-DL-Phe-DL-Gln-DL-Trp-DL-Pro-Gly-DL-Ser-DL-Trp-DL-xiThr-DL-Trp-DL-Glu-DL-Asn-Gly-DL-Lys-DL-Trp-DL-xiThr-DL-Trp-DL-Lys-Gly-DL-Ala-DL-Tyr-DL-Gln-DL-Phe-DL-Leu-DL-Lys-Gly-Gly-Gly-Gly-DL-Ser-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-OH; HGFQWPGSWXWENGKWXWKGAYQFLKGGGGSRRRRR RRRR; DL-histidyl-glycyl-DL-phenylalanyl-DL-glutaminyl-DL-tryptophyl-DL-prolyl-glycyl-DL-seryl-DL-tryptophyl-DL-threonyl-DL-tryptophyl-DL-alpha-glutamyl-DL-asparagyl-glycyl-DL-lysyl-DL-tryptophyl-DL-threonyl-DL-tryptophyl-DL-lysyl-glycyl-DL-alanyl-DL-tyrosyl-DL-glutaminyl-DL-phenylalanyl-DL-leucyl-DL-lysyl-glycyl-glycyl-glycyl-glycyl-DL-seryl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginyl-DL-arginine. Grades: 99.31 %. Molecular formula: C223H330N80O51. Mole weight: 4947.51.
APY0201, an effective IL-12/23 inhibitor, has been found to have potential use in the treatment of inflammation. IC50 = 5.2 nM. Synonyms: APY0201; APY-0201; APY 0201. Grades: 98%. CAS No. 1232221-74-7. Molecular formula: C23H23N7O. Mole weight: 413.48.
APY 29. Group: Biochemicals. Grades: Purified. CAS No. 1216665-49-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
apyrase
Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyse NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates. They differ from ATPases, which specifically hydrolyse ATP, by hydrolysing both ATP and ADP. The eukaryotic enzymes requires Ca2+, but Mg2+ can substitute. Most of the ecto-ATPases that occur on the cell surface and hydrolyse extracellular nucleotides belong to this enzyme family. Group: Enzymes. Synonyms: ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase [ambiguous]. Enzyme Commission Number: EC 3.6.1.5. CAS No. 9000-95-7. Apyrase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4623; apyrase; EC 3.6.1.5; 9000-95-7; ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase [ambiguous]. Cat No: EXWM-4623.
Apyrase
Apyrase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-95-7. Pack Sizes: 10 U; 100 U. Product ID: HY-P2764.
Apyrase from Potato, Recombinant
Apyrase is found in all eukaryotes and some prokaryotes. Apyrase, from potato, has a crucial role in regulating growth and development. Apyrase is involved in the inactivation of synaptic ATP as a neurotransmitter following nerve stimulation and in the inhibition of ADP induced platelet aggregation to prevent thrombosis. Divalent metal ions are required for activity and best activity is observed with calcium ion at 5 mM. Apyrase (recombinant, e. coli) is a highly active atp-diphosphohydrolase that catalyses the sequential hydrolysis of atp to adp and adp to amp releasing inorganic phosphate. it is a recombinant version of one of several isoforms of apyrase. it can also hydrol...version of 5? triphosphorylated rna to ligatable monophosphorylated form that can be used for 5? rna adaptor ligation. conversion of 5? triphosphorylated rna to 5? exonuclease xrn-1 sensitive monophosphorylated rna. Group: Enzymes. Synonyms: ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase; apyrase; EC 3.6.1.5; 9000-95-7. Apyrase. Mole weight: 47 kDa. Activity: 3,000 units/mg. Storage: at -20°C. Form: 50 mM NaCl, 20 mM MES (pH 6.5 25°C), 0.1 mM CaCl2, 1 mM DTT, 0.1% Tween-20 and 50% glycerol. Source: E. coli. Species: Potato. ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase; apyrase; EC 3.6.1.5; 9000-95-7. Cat No: NATE-1268.
AQ-13 dihydrochloride
AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum. Uses: Scientific research. Group: Signaling pathways. CAS No. 169815-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100358.
AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-9,10-anthraquinone, 70476-63-0, 72758-40-8, 1,4-Bis((2-(dimethylamino)ethyl)amino)-5,8-dihydroxyanthracene-9,10-dione, 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione, 1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione, AC1L36GN, AC1Q6J6J, SureCN3148984, CTK8D7828, KST-1B8141, AR-1B7623, 1,4-bis(2-dimethylaminoethylamino)-5,8-dihydroxyanthracene-9,10-dione, 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione, 9,10-Anthracenedione, 1,4-bis((2-(dimethylamino)ethyl)amino)-5,8-dihydroxy-. Product Category: Inhibitors. CAS No. 70476-63-0. Molecular formula: C22H28N4O4. Mole weight: 412.48. Purity: 0.96. IUPACName: 1,4-bis[2-(dimethylamino)ethylamino]-5,8-dihydroxyanthracene-9,10-dione. Canonical SMILES: CN(C)CCNC1=C2C(=C(C=C1)NCCN(C)C)C(=O)C3=C(C=CC(=C3C2=O)O)O. Product ID: ACM70476630. Alfa Chemistry ISO 9001:2015 Certified. Categories: AQ400.
AQC
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate. CAS No. 148757-94-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-117695.
AQ-RA 741
AQ-RA 741. Group: Biochemicals. Alternative Names: 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grades: Highly Purified. CAS No. 123548-16-3. Pack Sizes: 10mg. Molecular Formula: C27H37N5O2, Molecular Weight: 463.61. US Biological Life Sciences.
Worldwide
AQ-RA 741
AQ-RA 741 has been found to be a muscarinic M2 receptor antagonist and could probably be used in the development of bronchodilator anti-muscarinic agent. Synonyms: 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grades: ≥99% by HPLC. CAS No. 123548-16-3. Molecular formula: C27H37N5O2. Mole weight: 463.62.
aquacobalamin reductase
A flavoprotein. Group: Enzymes. Synonyms: aquocobalamin reductase; vitamin B12a reductase; NADH-linked aquacobalamin reductase; B12a reductase; NADH2:cob(III)alamin oxidoreductase. Enzyme Commission Number: EC 1.16.1.3. CAS No. 37256-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1068; aquacobalamin reductase; EC 1.16.1.3; 37256-39-6; aquocobalamin reductase; vitamin B12a reductase; NADH-linked aquacobalamin reductase; B12a reductase; NADH2:cob(III)alamin oxidoreductase. Cat No: EXWM-1068.
aquacobalamin reductase (NADPH)
A flavoprotein. Acts on aquacob(III)alamin and hydroxycobalamin, but not on cyanocobalamin. Group: Enzymes. Synonyms: aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-linked aquacobalamin reductase; NADPH2:aquacob(III)alamin oxidoreductase. Enzyme Commission Number: EC 1.16.1.5. CAS No. 110777-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1070; aquacobalamin reductase (NADPH); EC 1.16.1.5; 110777-32-7; aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-linked aquacobalamin reductase; NADPH2:aquacob(III)alamin oxidoreductase. Cat No: EXWM-1070.
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;Black
aqualysin 1
This enzyme from the extreme thermophile, Thermus aquaticus, is an alkaline serine peptidase. It has three subsites, S1, S2, and S3, in the substrate binding site. The preferred amino acids at the S1 site are Ala and Phe, at the S2 site are Ala and norleucine and at the S3 site are Phe and Ile. These specificities are similar to those of EC 3.4.21.64 (peptidase K) and EC 3.4.21.62 (subtilisin BPN'). The enzyme displays broad specificity for cleavage of insulin B-chain and hydrolyses elastin substrates such as succinyl-(Ala)n-p-nitroanilide (n = 1,2,3) and some peptide esters. Belongs in peptidase family S8A. Group: Enzymes. Synonyms: caldolysin. Enzyme Commission Number: EC 3.4.21.111. CAS No. 88747-68-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4106; aqualysin 1; EC 3.4.21.111; 88747-68-6; caldolysin. Cat No: EXWM-4106.
Aquamate
Aquamate (Marine Formate, Aphermate). CAS No. 25225-08-5. Kosher: Y. VIGON Item # 503553. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers.