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| Product | Description | |
|---|---|---|
| Avanafil Impurity 26 | Avanafil Impurity 26. Uses: For analytical and research use. Alternative Names: (S)-ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C20H25ClN4O4. Mole weight: 420.89. Catalog: APB02778. |  |
| Avanafil Impurity 27 | Avanafil Impurity 27. Uses: For analytical and research use. Alternative Names: (R)-ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C20H25ClN4O4. Mole weight: 420.89. Catalog: APB02775. | |
| Avanafil Impurity 28 | Avanafil Impurity 28. Uses: For analytical and research use. Alternative Names: (S)-ethyl 2-(2-(hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)pyrimidine-5-carboxylate. Molecular formula: C20H26N4O4. Mole weight: 386.44. Catalog: APB02774. | |
| Avanafil Impurity 29 | Avanafil Impurity 29. Uses: For analytical and research use. Alternative Names: (S)-ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C20H24Cl2N4O4. Mole weight: 455.33. Catalog: APB02776. | |
| Avanafil Impurity 29 | Avanafil Impurity 29. Uses: For analytical and research use. CAS No. 1364671-52-2. Molecular formula: C19H19ClN6O3S. Mole weight: 446.91. Catalog: APB1364671522. | |
| Avanafil Impurity 3 | Avanafil Impurity 3. Uses: For analytical and research use. CAS No. 2250242-48-7. Molecular formula: C16H17Cl2N3O3S. Mole weight: 402.29. Catalog: APB2250242487. | |
| Avanafil Impurity 3 | Avanafil Impurity 3. Uses: For analytical and research use. Alternative Names: ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C8H10N2O3S. Mole weight: 214.24. Catalog: APB02659. | |
| Avanafil Impurity 30 | Avanafil Impurity 30. Uses: For analytical and research use. Alternative Names: (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid. CAS No. 330785-84-7. Molecular formula: C18H21ClN4O4. Mole weight: 392.84. Catalog: APB330785847. | |
| Avanafil Impurity 31 | Avanafil Impurity 31. Uses: For analytical and research use. Alternative Names: (R)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid. Molecular formula: C18H21ClN4O4. Mole weight: 392.84. Catalog: APB02773. | |
| Avanafil Impurity 32 | Avanafil Impurity 32. Uses: For analytical and research use. CAS No. 53554-29-3. Molecular formula: C8H10N2O3S. Mole weight: 214.24. Catalog: APB53554293. | |
| Avanafil Impurity 32 | Avanafil Impurity 32. Uses: For analytical and research use. Alternative Names: (S)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)pyrimidine-5-carboxylic acid. Molecular formula: C18H22N4O4. Mole weight: 358.39. Catalog: APB02771. | |
| Avanafil Impurity 33 | Avanafil Impurity 33. Uses: For analytical and research use. Alternative Names: (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid. Molecular formula: C18H20Cl2N4O4. Mole weight: 427.28. Catalog: APB02770. | |
| Avanafil Impurity 33 | Avanafil Impurity 33. Uses: For analytical and research use. CAS No. 247569-72-8. Molecular formula: C8H10ClNO. Mole weight: 171.62. Catalog: APB247569728. | |
| Avanafil Impurity 34 | Avanafil Impurity 34. Uses: For analytical and research use. Alternative Names: (R)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular formula: C23H26ClN7O3. Mole weight: 483.95. Catalog: APB02772. | |
| Avanafil Impurity 35 | Avanafil Impurity 35. Uses: For analytical and research use. Alternative Names: (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular formula: C23H25Cl2N7O3. Mole weight: 518.4. Catalog: APB02768. | |
| Avanafil Impurity 36 | Avanafil Impurity 36. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular formula: C19H19ClN6O2S. Mole weight: 430.91. Catalog: APB02769. | |
| Avanafil Impurity 37 | Avanafil Impurity 37. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. CAS No. 1452128-53-8. Molecular formula: C18H17ClN6O3. Mole weight: 400.82. Catalog: APB1452128538. | |
| Avanafil Impurity 37 | Avanafil Impurity 37. Uses: For analytical and research use. CAS No. 2250242-49-8. Molecular formula: C18H23N5O3. Mole weight: 357.41. Catalog: APB2250242498. | |
| Avanafil Impurity 38 | Avanafil Impurity 38. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-hydroxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular formula: C17H15ClN6O3. Mole weight: 386.79. Catalog: APB02767. | |
| Avanafil Impurity 39 | Avanafil Impurity 39. Uses: For analytical and research use. Alternative Names: ethyl 4-((3-chloro-4-hydroxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C15H16ClN3O3S. Mole weight: 353.82. Catalog: APB02765. | |
| Avanafil Impurity 39 | Avanafil Impurity 39. Uses: For analytical and research use. CAS No. 23356-96-9. Molecular formula: C5H11NO. Mole weight: 101.15. Catalog: APB23356969. | |
| Avanafil Impurity 4 | Avanafil Impurity 4. Uses: For analytical and research use. CAS No. 874482-97-0. Molecular formula: C8H11Cl2NO. Mole weight: 208.08. Catalog: APB874482970. | |
| Avanafil Impurity 4 | Avanafil Impurity 4. Uses: For analytical and research use. Alternative Names: ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C16H19N3O3S. Mole weight: 333.41. Catalog: APB02657. | |
| Avanafil Impurity 40 | Avanafil Impurity 40. Uses: For analytical and research use. CAS No. 68832-13-3. Molecular formula: C5H11NO. Mole weight: 101.15. Catalog: APB68832133. | |
| Avanafil Impurity 40 | Avanafil Impurity 40. Uses: For analytical and research use. Alternative Names: (S)-ethyl 4-((3-chloro-4-hydroxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C19H23ClN4O4. Mole weight: 406.86. Catalog: APB02766. | |
| Avanafil Impurity 41 | Avanafil Impurity 41. Uses: For analytical and research use. Alternative Names: (S)-4-((3-chloro-4-hydroxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid. Molecular formula: C17H19ClN4O4. Mole weight: 378.81. Catalog: APB02764. | |
| Avanafil Impurity 41 | Avanafil Impurity 41. Uses: For analytical and research use. CAS No. 56633-75-1. Molecular formula: C6H11NO2. Mole weight: 129.16. Catalog: APB56633751. | |
| Avanafil Impurity 42 | Avanafil Impurity 42. Uses: For analytical and research use. CAS No. 61350-65-0. Molecular formula: C6H11NO2. Mole weight: 129.16. Catalog: APB61350650. | |
| Avanafil Impurity 42 | Avanafil Impurity 42. Uses: For analytical and research use. Alternative Names: (S)-(1-(4-((3-chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl acetate. Molecular formula: C25H28ClN7O4. Mole weight: 525.99. Catalog: APB02762. | |
| Avanafil Impurity 43 | Avanafil Impurity 43. Uses: For analytical and research use. Alternative Names: (S)-ethyl 4-((3-chlorobenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C19H23ClN4O3. Mole weight: 390.86. Catalog: APB02763. | |
| Avanafil Impurity 44 | Avanafil Impurity 44. Uses: For analytical and research use. Alternative Names: 4-((3-chlorobenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid. Molecular formula: C13H12ClN3O2S. Mole weight: 309.77. Catalog: APB02761. | |
| Avanafil Impurity 45 | Avanafil Impurity 45. Uses: For analytical and research use. Alternative Names: ethyl 4-((3-chlorobenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C15H16ClN3O2S. Mole weight: 337.82. Catalog: APB02760. | |
| Avanafil Impurity 46 | Avanafil Impurity 46. Uses: For analytical and research use. Alternative Names: (S)-4-((3-chlorobenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. Molecular formula: C22H24ClN7O2. Mole weight: 453.92. Catalog: APB02759. | |
| Avanafil Impurity 5 | Avanafil Impurity 5. Uses: For analytical and research use. Alternative Names: ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C16H17Cl2N3O3S. Mole weight: 402.3. Catalog: APB02654. | |
| Avanafil Impurity 50 | Avanafil Impurity 50. Uses: For analytical and research use. CAS No. 2310299-29-5. Molecular formula: C14H14ClN3O5S. Mole weight: 371.79. Catalog: APB2310299295. | |
| Avanafil Impurity 51 | Avanafil Impurity 51. Uses: For analytical and research use. CAS No. 1624833-89-1. Molecular formula: C19H19ClN6O4S. Mole weight: 462.91. Catalog: APB1624833891. | |
| Avanafil Impurity 52 | Avanafil Impurity 52. Uses: For analytical and research use. CAS No. 1711677-06-3. Molecular formula: C20H23ClN4O5. Mole weight: 434.88. Catalog: APB1711677063. | |
| Avanafil Impurity 56 | Avanafil Impurity 56. Uses: For analytical and research use. CAS No. 1830294-64-8. Molecular formula: C23H24ClN7O4. Mole weight: 497.94. Catalog: APB1830294648. | |
| Avanafil Impurity 6 | Avanafil Impurity 6. Uses: For analytical and research use. Alternative Names: ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate. Molecular formula: C16H18ClN3O3S. Mole weight: 367.85. Catalog: APB02655. | |
| Avanafil Impurity 6 | Avanafil Impurity 6. Uses: For analytical and research use. CAS No. 2520113-98-6. Molecular formula: C24H24ClN7O4. Mole weight: 509.95. Catalog: APB2520113986. | |
| Avanafil Impurity 63 | Avanafil Impurity 63. Uses: For analytical and research use. CAS No. 59566-45-9. Molecular formula: C6H5N3. Mole weight: 119.13. Catalog: APB59566459. | |
| Avanafil Impurity 68 | Avanafil Impurity 68. Uses: For analytical and research use. CAS No. 41965-95-1. Molecular formula: C8H11Cl2NO. Mole weight: 208.08. Catalog: APB41965951. | |
| Avanafil Impurity 69 | Avanafil Impurity 69. Uses: For analytical and research use. CAS No. 5909-24-0. Molecular formula: C8H9ClN2O2S. Mole weight: 232.68. Catalog: APB5909240. | |
| Avanafil Impurity 7 | Avanafil Impurity 7. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid. Molecular formula: C14H14ClN3O3S. Mole weight: 339.8. Catalog: APB02656. | |
| Avanafil Impurity 7 | Avanafil Impurity 7. Uses: For analytical and research use. CAS No. 1638497-26-3. Molecular formula: C23H26ClN7O3. Mole weight: 483.96. Catalog: APB1638497263. | |
| Avanafil Impurity 75 | Avanafil Impurity 75. Uses: For analytical and research use. Molecular formula: C26H38ClN7O4. Mole weight: 548.09. Catalog: APB06513. | |
| Avanafil Impurity 76 | Avanafil Impurity 76. Uses: For analytical and research use. Molecular formula: C23H26ClN7O4. Mole weight: 499.96. Catalog: APB06514. | |
| Avanafil Impurity 77 | Avanafil Impurity 77. Uses: For analytical and research use. Molecular formula: C23H26ClN7O4. Mole weight: 499.96. Catalog: APB06515. | |
| Avanafil Impurity 78 | Avanafil Impurity 78. Uses: For analytical and research use. Molecular formula: C41H45Cl2N11O6. Mole weight: 858.78. Catalog: APB06517. | |
| Avanafil Impurity 79 | Avanafil Impurity 79. Uses: For analytical and research use. Molecular formula: C26H38ClN7O4. Mole weight: 548.09. Catalog: APB06516. | |
| Avanafil Impurity 8 | Avanafil Impurity 8. Uses: For analytical and research use. Alternative Names: (S)-4-((3-chloro-4-hydroxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide. CAS No. 330785-05-2. Molecular formula: C22H24ClN7O3. Mole weight: 469.92. Catalog: APB330785052. | |
| Avanafil Impurity 8 | Avanafil Impurity 8. Uses: For analytical and research use. CAS No. 2221018-00-2. Molecular formula: C30H30Cl2N6O7. Mole weight: 657.51. Catalog: APB2221018002. | |
| Avanafil Impurity 80 | Avanafil Impurity 80. Uses: For analytical and research use. CAS No. 2259648-80-9. Molecular formula: C32H30FN5O4. Mole weight: 567.62. Catalog: APB2259648809. | |
| Avanafil Impurity 81 | Avanafil Impurity 81. Uses: For analytical and research use. Molecular formula: C23H27N7O4. Mole weight: 465.51. Catalog: APB06518. | |
| Avanafil Impurity 82 | Avanafil Impurity 82. Uses: For analytical and research use. CAS No. 372115-53-2. Molecular formula: C24H29N7O4. Mole weight: 479.54. Catalog: APB372115532. | |
| Avanafil Impurity 83 | Avanafil Impurity 83. Uses: For analytical and research use. CAS No. 372117-76-5. Molecular formula: C16H18ClN3O5S. Mole weight: 399.85. Catalog: APB372117765. | |
| Avanafil Impurity 9 | Avanafil Impurity 9. Uses: For analytical and research use. CAS No. 2520114-34-3. Molecular formula: C23H26ClN7O3. Mole weight: 483.96. Catalog: APB2520114343. | |
| Avanafil Impurity 9 | Avanafil Impurity 9. Uses: For analytical and research use. Alternative Names: ((S)-1-(4-((3-chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate. Molecular formula: C41H45Cl2N11O6. Mole weight: 858.77. Catalog: APB02653. | |
| Avanafil Impurity O | Avanafil Impurity O. Uses: For analytical and research use. CAS No. 330785-83-6. Molecular formula: C20H25ClN4O4. Mole weight: 420.89. Catalog: APB330785836. | |
| Avanafil Impurity P | Avanafil Impurity P. Uses: For analytical and research use. CAS No. 330785-81-4. Molecular formula: C16H18ClN3O3S. Mole weight: 367.85. Catalog: APB330785814. | |
| Avanafil Impurity R-1 | Avanafil Impurity R-1. Uses: For analytical and research use. CAS No. 1638497-22-9. Molecular formula: C20H25ClN4O4. Mole weight: 420.89. Catalog: APB1638497229. | |
| Avanafil Impurity R-2 | Avanafil Impurity R-2. Uses: For analytical and research use. CAS No. 1638497-25-2. Molecular formula: C18H21ClN4O4. Mole weight: 392.84. Catalog: APB1638497252. | |
| Avanafil Impurity V | Avanafil Impurity V. Uses: For analytical and research use. CAS No. 330785-99-4. Molecular formula: C15H16ClN3O4. Mole weight: 337.76. Catalog: APB330785994. | |
| Avanafil metabolite M4 | Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M4 and avanafil metabolite M16, as well as minor metabolites. Avanafil metabolite M4 inhibits PDE5 with 18% of the potency of avanafil. Grade: ≥98%. Molecular formula: C23H26ClN7O4. Mole weight: 499.95. |  |
| Avanafil Related Compound 1 | Avanafil Related Compound 1 is a pivotal entity within the biomedical research, primarily employed in the synthesand exploration of Avanafil, a pharmaceutical intervention targeting erectile dysfunction. Synonyms: 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylsulfinylpyriMidine; Ethyl 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(Methylsulfinyl)pyriMidine-5-carboxylate. Grade: > 95%. CAS No. 330785-82-5. Molecular formula: C16H18ClN3O4S. Mole weight: 383.86. | |
| Avanafil Related Compound 1 | Avanafil Related Compound 1. Uses: For analytical and research use. CAS No. 330785-82-5. Molecular formula: C16H18ClN3O4S. Mole weight: 383.85. Catalog: APB330785825. | |
| Avanafil Related Compound 2 | Avanafil Related Compound 2. Uses: For analytical and research use. CAS No. 1364671-62-4. Molecular formula: C19H19ClN6O2S. Mole weight: 430.91. Catalog: APB1364671624. | |
| Avanbulin | Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC50 of 1.4 μM. Avanbulin binds to tubulin with an apparent Kd value of 244 nM. Avanbulin can be used for the research of cancer and cell division[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAL27862. CAS No. 798577-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106008. |  |
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Synonyms: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Molecular formula: C26H27FN10. Mole weight: 498.56. | |
| Avapritinib | Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases, targeting KIT D816V (IC50:0.27 nM) and PDGFRA D842V (IC50:0.24 nM), and attenuates the transport functions of ABCB1 and ABCG2. It binds to the active conformation of the kinases and exhibits antitumor activity. Category: Active pharmaceutical ingredients. CAS No. 1703793-34-3. Product ID: API1703793343. Molecular formula: C26H27FN10. Mole weight: 498.56. |  |
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