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| Product | Description | |
|---|---|---|
| Avatrombopag Impurity 54 | Avatrombopag Impurity 54. Uses: For analytical and research use. Alternative Names: ethyl 1-(1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carbonyl)piperidine-4-carboxylate. Molecular formula: C37H47Cl2N7O4S2. Mole weight: 788.85. Catalog: APB01801. |  |
| Avatrombopag Impurity 55 | Avatrombopag Impurity 55. Uses: For analytical and research use. Alternative Names: 1,2,3-tris(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)guanidine. Molecular formula: C52H65Cl3N12S6. Mole weight: 1156.90. Catalog: APB02913. | |
| Avatrombopag Impurity 56 | Avatrombopag Impurity 56. Uses: For analytical and research use. Alternative Names: methyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate. Molecular formula: C30H36Cl2N6O3S2. Mole weight: 663.68. Catalog: APB01182. | |
| Avatrombopag Impurity 57 | Avatrombopag Impurity 57. Uses: For analytical and research use. Alternative Names: ethyl 1-isonicotinoylpiperidine-4-carboxylate. CAS No. 252263-38-0. Molecular formula: C14H18N2O3. Mole weight: 262.30. Catalog: APB252263380. | |
| Avatrombopag Impurity 57 (Hydrochloride) | Avatrombopag Impurity 57 (Hydrochloride). Uses: For analytical and research use. Alternative Names: ethyl 1-isonicotinoylpiperidine-4-carboxylate hydrochloride. CAS No. 1798161-60-0. Molecular formula: C14H18N2O3·HCl. Mole weight: 298.77. Catalog: APB1798161600. | |
| Avatrombopag Impurity 58 | Avatrombopag Impurity 58. Uses: For analytical and research use. Alternative Names: 1-(5-((4-(4-bromothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic acid. Molecular formula: C29H34BrClN6O3S2. Mole weight: 694.11. Catalog: APB02912. | |
| Avatrombopag Impurity 59 | Avatrombopag Impurity 59. Uses: For analytical and research use. Alternative Names: 5-chloro-6-(4-(4-(ethoxycarbonyl)piperidine-1-carbonyl)piperidin-1-yl)nicotinic acid. Molecular formula: C20H26ClN3O5. Mole weight: 423.89. Catalog: APB01181. | |
| Avatrombopag Impurity 6 | Avatrombopag Impurity 6. Uses: For analytical and research use. Alternative Names: 4-(4-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 570407-10-2. Molecular formula: C7H5ClN2S2. Mole weight: 216.71. Catalog: APB570407102. | |
| Avatrombopag Impurity 60 | Avatrombopag Impurity 60. Uses: For analytical and research use. Molecular formula: C16H21Cl2N3O. Mole weight: 342.26. Catalog: APB10953. | |
| Avatrombopag Impurity 60 | Avatrombopag Impurity 60. Uses: For analytical and research use. Alternative Names: ethyl 1-(piperidine-4-carbonyl)piperidine-4-carboxylate. CAS No. 901314-75-8. Molecular formula: C14H24N2O3. Mole weight: 268.35. Catalog: APB901314758. | |
| Avatrombopag Impurity 60 (Hydrochloride) | Avatrombopag Impurity 60 (Hydrochloride). Uses: For analytical and research use. Alternative Names: ethyl 1-(piperidine-4-carbonyl)piperidine-4-carboxylate hydrochloride. Molecular formula: C14H24N2O3·HCl. Mole weight: 304.81. Catalog: APB01180. | |
| Avatrombopag Impurity 61 | Avatrombopag Impurity 61. Uses: For analytical and research use. Molecular formula: C24H35ClN4O3. Mole weight: 463.02. Catalog: APB10954. | |
| Avatrombopag Impurity 61 | Avatrombopag Impurity 61. Uses: For analytical and research use. Alternative Names: 1-(5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-3-hydroxypyridin-2-yl)piperidine-4-carboxylic acid. CAS No. 1290121-42-4. Molecular formula: C29H35ClN6O4S2. Mole weight: 631.21. Catalog: APB1290121424. | |
| Avatrombopag Impurity 62 | Avatrombopag Impurity 62. Uses: For analytical and research use. Alternative Names: 1-(2-amino-4-(4-chlorothiophen-2-yl)thiazol-5-yl)-4-cyclohexylpiperazine 1-oxide. Molecular formula: C17H23ClN4OS2. Mole weight: 398.97. Catalog: APB02911. | |
| Avatrombopag Impurity 63 | Avatrombopag Impurity 63. Uses: For analytical and research use. Molecular formula: C24H35ClN4O3. Mole weight: 463.02. Catalog: APB10955. | |
| Avatrombopag Impurity 64 | Avatrombopag Impurity 64. Uses: For analytical and research use. Alternative Names: 3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)-2-(4-(ethoxycarbonyl)piperidin-1-yl)pyridine 1-oxide. Molecular formula: C31H38Cl2N6O4S2. Mole weight: 693.71. Catalog: APB02910. | |
| Avatrombopag Impurity 65 | Avatrombopag Impurity 65. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(3-chlorothiophen-2-yl)thiazol-2-amine. Molecular formula: C7H4BrClN2S2. Mole weight: 295.61. Catalog: APB02909. | |
| Avatrombopag Impurity 66 | Avatrombopag Impurity 66. Uses: For analytical and research use. Molecular formula: C7H4Br2N2S2. Mole weight: 340.05. Catalog: APB10956. | |
| Avatrombopag Impurity 66 | Avatrombopag Impurity 66. Uses: For analytical and research use. Alternative Names: 2-bromo-1-(4-chlorothiophen-2-yl)ethanone. CAS No. 677007-73-7. Molecular formula: C6H4BrClOS. Mole weight: 239.52. Catalog: APB677007737. | |
| Avatrombopag Impurity 67 | Avatrombopag Impurity 67. Uses: For analytical and research use. Alternative Names: piperidine-4-carboxylic acid. CAS No. 498-94-2. Molecular formula: C6H11NO2. Mole weight: 129.16. Catalog: APB498942. | |
| Avatrombopag Impurity 68 | Avatrombopag Impurity 68. Uses: For analytical and research use. Alternative Names: 6-hydroxynicotinic acid. CAS No. 5006-66-6. Molecular formula: C6H5NO3. Mole weight: 139.11. Catalog: APB5006666. | |
| Avatrombopag Impurity 69 | Avatrombopag Impurity 69. Uses: For analytical and research use. Alternative Names: 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid. Molecular formula: C19H16Cl2N4O3S2. Mole weight: 483.39. Catalog: APB02908. | |
| Avatrombopag Impurity 7 | Avatrombopag Impurity 7. Uses: For analytical and research use. Alternative Names: 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine. CAS No. 570407-42-0. Molecular formula: C17H23ClN4S2. Mole weight: 382.97. Catalog: APB570407420. | |
| Avatrombopag Impurity 70 | Avatrombopag Impurity 70. Uses: For analytical and research use. Alternative Names: 5-(4-carboxypiperidin-1-yl)-6-chloronicotinic acid. Molecular formula: C12H13ClN2O4. Mole weight: 284.70. Catalog: APB02907. | |
| Avatrombopag Impurity 71 | Avatrombopag Impurity 71. Uses: For analytical and research use. Alternative Names: 4-(4-(4-cyclohexylpiperazin-1-yl)thiophen-2-yl)thiazol-2-amine. Molecular formula: C17H24N4S2. Mole weight: 348.53. Catalog: APB02905. | |
| Avatrombopag Impurity 72 | Avatrombopag Impurity 72. Uses: For analytical and research use. CAS No. 3335-5-5. Molecular formula: C8H13NO2. Mole weight: 155.2. Catalog: APB3335055. | |
| Avatrombopag Impurity 72 | Avatrombopag Impurity 72. Uses: For analytical and research use. Alternative Names: ethyl 1-(5-(2-aminothiazol-4-yl)thiophen-3-yl)piperidine-4-carboxylate. Molecular formula: C15H19N3O2S2. Mole weight: 337.46. Catalog: APB02906. | |
| Avatrombopag Impurity 73 | Avatrombopag Impurity 73. Uses: For analytical and research use. Alternative Names: ethyl 1-(5-(2-amino-5-(4-cyclohexylpiperazin-1-yl)thiazol-4-yl)thiophen-3-yl)piperidine-4-carboxylate. Molecular formula: C25H37N5O2S2. Mole weight: 503.72. Catalog: APB03315. | |
| Avatrombopag Impurity 74 | Avatrombopag Impurity 74. Uses: For analytical and research use. Alternative Names: ethyl 1-(2-(4-chlorothiophen-2-yl)-2-oxoethyl)piperidine-4-carboxylate. Molecular formula: C14H18ClNO3S. Mole weight: 315.82. Catalog: APB01178. | |
| Avatrombopag Impurity 75 | Avatrombopag Impurity 75. Uses: For analytical and research use. Alternative Names: 2-bromo-1-(5-bromo-4-chlorothiophen-2-yl)ethanone. Molecular formula: C6H3Br2ClOS. Mole weight: 318.41. Catalog: APB01179. | |
| Avatrombopag Impurity 76 | Avatrombopag Impurity 76. Uses: For analytical and research use. Alternative Names: 2,2-dibromo-1-(5-bromo-4-chlorothiophen-2-yl)ethanone. Molecular formula: C6H2Br3ClOS. Mole weight: 397.31. Catalog: APB01177. | |
| Avatrombopag Impurity 77 | Avatrombopag Impurity 77. Uses: For analytical and research use. Alternative Names: 2,2-dichloro-1-(4,5-dichlorothiophen-2-yl)ethanone. Molecular formula: C6H2Cl4OS. Mole weight: 263.96. Catalog: APB01176. | |
| Avatrombopag Impurity 78 | Avatrombopag Impurity 78. Uses: For analytical and research use. Alternative Names: 2-chloro-1-(4,5-dichlorothiophen-2-yl)ethanone. CAS No. 64218-50-4. Molecular formula: C6H3Cl3Os. Mole weight: 229.51. Catalog: APB64218504. | |
| Avatrombopag Impurity 79 | Avatrombopag Impurity 79. Uses: For analytical and research use. Alternative Names: 4-cyclohexylpiperazine-1-carbaldehyde. CAS No. 2325305-38-0. Molecular formula: C11H20N2O. Mole weight: 196.29. Catalog: APB2325305380. | |
| Avatrombopag Impurity 8 | Avatrombopag Impurity 8. Uses: For analytical and research use. Alternative Names: 5,6-dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide. CAS No. 570403-04-2. Molecular formula: C23H24Cl3N5OS2. Mole weight: 556.96. Catalog: APB570403042. | |
| Avatrombopag Impurity 80 | Avatrombopag Impurity 80. Uses: For analytical and research use. Alternative Names: 1-(3-chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid. Molecular formula: C29H35ClN6O3S2. Mole weight: 615.21. Catalog: APB03314. | |
| Avatrombopag Impurity 82 | Avatrombopag Impurity 82. Uses: For analytical and research use. Alternative Names: 4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 1534575-19-3. Molecular formula: C7H4BrClN2S2. Mole weight: 293.87. Catalog: APB1534575193. | |
| Avatrombopag Impurity 83 | Avatrombopag Impurity 83. Uses: For analytical and research use. Alternative Names: 4-(thiophen-2-yl)thiazol-2-amine. CAS No. 28989-50-6. Molecular formula: C7H6N2S2. Mole weight: 182.27. Catalog: APB28989506. | |
| Avatrombopag Impurity 84 | Avatrombopag Impurity 84. Uses: For analytical and research use. Alternative Names: 4-(4-bromothiophen-2-yl)thiazol-2-amine. CAS No. 81216-89-9. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB81216899. | |
| Avatrombopag Impurity 85 | Avatrombopag Impurity 85. Uses: For analytical and research use. Alternative Names: 4-(5-bromothiophen-2-yl)thiazol-2-amine. CAS No. 34801-14-4. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB34801144. | |
| Avatrombopag Impurity 86 | Avatrombopag Impurity 86. Uses: For analytical and research use. Alternative Names: ethyl 1,2,3,6-tetrahydropyridine-4-carboxylate. CAS No. 40240-23-1. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB40240231. | |
| Avatrombopag Impurity 87 | Avatrombopag Impurity 87. Uses: For analytical and research use. Alternative Names: ethyl 1,2,3,4-tetrahydropyridine-4-carboxylate. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB03312. | |
| Avatrombopag Impurity 88 | Avatrombopag Impurity 88. Uses: For analytical and research use. Alternative Names: ethyl 2,3,4,5-tetrahydropyridine-4-carboxylate. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB03313. | |
| Avatrombopag Impurity 89 | Avatrombopag Impurity 89. Uses: For analytical and research use. Alternative Names: 1-(4-cyclohexylpiperazin-1-yl)ethanone. CAS No. 91695-59-9. Molecular formula: C12H22N2O. Mole weight: 210.32. Catalog: APB91695599. | |
| Avatrombopag Impurity 9 | Avatrombopag Impurity 9. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate. CAS No. 570403-14-4. Molecular formula: C31H38Cl2N6O3S2. Mole weight: 677.71. Catalog: APB570403144. | |
| Avatrombopag Impurity 90 | Avatrombopag Impurity 90. Uses: For analytical and research use. Alternative Names: (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-2-yl)methanone. Molecular formula: C16H21Cl2N3O. Mole weight: 342.26. Catalog: APB03310. | |
| Avatrombopag Impurity 91 | Avatrombopag Impurity 91. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-6-(4-cyclohexylpiperazine-1-carbonyl)pyridin-2-yl)piperidine-4-carboxylate. Molecular formula: C24H35ClN4O3. Mole weight: 463.01. Catalog: APB03311. | |
| Avatrombopag Impurity 92 | Avatrombopag Impurity 92. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-5-(4-cyclohexylpiperazine-1-carbonyl)pyridin-2-yl)piperidine-4-carboxylate. CAS No. 2948773-24-6. Molecular formula: C24H35ClN4O3. Mole weight: 463.01. Catalog: APB2948773246. | |
| Avatrombopag Impurity 93 | Avatrombopag Impurity 93. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(thiophen-2-yl)thiazol-2-amine. CAS No. 81216-84-4. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB81216844. | |
| Avatrombopag Impurity 94 | Avatrombopag Impurity 94. Uses: For analytical and research use. Alternative Names: 5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-amine. Molecular formula: C17H24N4S2. Mole weight: 348.53. Catalog: APB03309. | |
| Avatrombopag Impurity 95 | Avatrombopag Impurity 95. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(4-bromothiophen-2-yl)thiazol-2-amine. Molecular formula: C7H4Br2N2S2. Mole weight: 340.06. Catalog: APB03308. | |
| Avatrombopag Impurity 96 | Avatrombopag Impurity 96. Uses: For analytical and research use. Alternative Names: 4-(4-bromothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine. CAS No. 570407-44-2. Molecular formula: C17H23BrN4S2. Mole weight: 427.43. Catalog: APB570407442. | |
| Avatrombopag Impurity 97 | Avatrombopag Impurity 97. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(5-bromothiophen-2-yl)thiazol-2-amine. CAS No. 81216-88-8. Molecular formula: C7H4Br2N2S2. Mole weight: 340.06. Catalog: APB81216888. | |
| Avatrombopag Impurity 98 | Avatrombopag Impurity 98. Uses: For analytical and research use. Alternative Names: 4-(5-bromothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine. CAS No. 570407-27-1. Molecular formula: C17H23BrN4S2. Mole weight: 427.43. Catalog: APB570407271. | |
| Avatrombopag Impurity 99 | Avatrombopag Impurity 99. Uses: For analytical and research use. Alternative Names: 1,4-dicyclohexylpiperazine. CAS No. 19982-04-8. Molecular formula: C16H30N2. Mole weight: 250.42. Catalog: APB19982048. | |
| Avatrombopag maleate | Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AKR-501 maleate; E5501 maleate; YM477 maleate. CAS No. 677007-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-13463A. |  |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. CAS No. 677007-74-8. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. |  |
| Avatrombopag (Maleate) | Avatrombopag (Maleate). Uses: For analytical and research use. Alternative Names: 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid compound with maleic acid (1:1). CAS No. 677007-74-8. Molecular formula: C29H34Cl2N6O3S2·C4H4O4. Mole weight: 765.72. Catalog: APB677007748. | |
| Avatrombopag Meleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Category: Other apis. Synonyms: E5501 MALEATE. UNII-GDW7M2P1IS. GDW7M2P1IS. CAS No. 677007-74-8. Product ID: API677007748. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. EINECS: 973-683-4. SMILES: C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl.C(=CC(=O)O)C(=O)O. |  |
| AvBD10 | AvBD10 is an antimicrobial peptide produced by liver, Peking duck, Anas platyrhynchos (Domestic duck). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Duck AvBD10; Duck avian beta defensin 10; Val-Leu-Leu-Phe-Leu-Phe-Gln-Ala-Ala-Pro-Gly-Ser-Ala-Asp-Ala-Pro-Phe-Ala-Asp-Thr-Ala-Ala-Cys-Arg-Ser-Gln-Gly-Asn-Phe-Cys-Arg-Ala-Gly-Ala-Cys-Pro-Pro-Thr-Phe-Ala-Ala-Ser-Gly-Ser-Cys-His-Gly-Gly-Leu-Leu-Asn-Cys-Cys-Ala-Lys. Grade: >98%. | |
| AVB-S6-500 | AVB-S6-500 is a GAS6-AXL signaling pathway blocker with high affnity for GAS6. AVB-S6-500 is developed for the treatment of cancer and nonmalignant fibrotic conditions as a drug candidate. It is in a phase I clinical trial for its safety and tolerability study. Uses: Potential treatment of cancer and nonmalignant fibrotic conditions. Synonyms: Aravive-S6. | |
| Avdoralimab | Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450. | |
| AVE-0118 | AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grade: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57. | |
| AVE 0118 hydrochloride | AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grade: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03. | |
| AVE 0991 | AVE 0991 is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: 1-ethyl-3-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea5-formyl-4-methoxy-2-phenyl-1-((4-(2-ethyl-aminocarbonylsulfonamido-5-isobutyl-3-thienyl)phenyl)methyl)imidiazoleAVE 0991; AVE-0991; AVE0991. CAS No. 304462-19-9. Molecular formula: C29H32N4O5S2. Mole weight: 580.72. | |
| AVE 0991 sodium salt | AVE 0991 sodium salt, is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: AVE-0991 sodium salt; AVE 0991 sodium salt; AVE0991 sodium salt; sodium; ethylcarbamoyl-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylazanideAVE 0991 (sodium salt)306288-04-0C29H31N4NaO5S23195AH. CAS No. 306288-04-0. Molecular formula: C29H31N4NaO5S2. Mole weight: 602.70. | |
| AVE5688 | AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes. Uses: Scientific research. Category: Signaling pathways. CAS No. 613260-13-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100320. | |
| AVE-8063 | AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity. Synonyms: AVE8063; AVE 8063; (Z)-1-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl) aniline. Grade: >98%. CAS No. 162705-07-9. Molecular formula: C18H21NO4. Mole weight: 315.37. | |
| AVE-8134 | AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively. Synonyms: AVE8134; 2-Methyl-6-((3-((2-phenyloxazol-4-yl)methoxy)propoxy)methyl)benzoic acid. CAS No. 304025-09-0. Molecular formula: C22H23NO5. Mole weight: 381.42. | |
| Avelumab | Avelumab (Anti-Human PD-L1) a fully human IgG1 anti-PD-L1 monoclonal antibody (mAb) with potential antibody-dependent cell-mediated cytotoxicity (ADCC). Avelumab enhances ADCC on several cancer cell lines expressing PD-L1. Avelumab can be used for the study of chordoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730. | |
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