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The enzyme from the bacterium Stigmatella aurantiaca catalyses the final step in the conversion of aurachin C to aurachin B. In vivo the enzyme catalyses the reduction of 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide to form 2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-3,4-diol (note that the reactions written above proceed from right to left), which then undergoes a spontaneous dehydration to form aurachin B. Group: Enzymes. Synonyms: AuaH. Enzyme Commission Number: EC 1.1.1.394. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0314; aurachin B dehydrogenase; EC 1.1.1.394; AuaH. Cat No: EXWM-0314.
Aurachin C
Aurachin C is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-14-9. Molecular formula: C25H33NO2. Mole weight: 379.53.
aurachin C monooxygenase/isomerase
The aurachin C monooxygenase from the bacterium Stigmatella aurantiaca accepts both NADH and NADPH as cofactor, but has a preference for NADH. It catalyses the initial steps in the conversion of aurachin C to aurachin B. The FAD-dependent monooxygenase catalyses the epoxidation of the C2-C3 double bond of aurachin C, which is followed by a semipinacol rearrangement, causing migration of the farnesyl group from C3 to C4. Group: Enzymes. Synonyms: auaG (gene name); aurachin C monooxygenase. Enzyme Commission Number: EC 1.14.13.222. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0825; aurachin C monooxygenase/isomerase; EC 1.14.13.222; auaG (gene name); aurachin C monooxygenase. Cat No: EXWM-0825.
Aurachin D
Aurachin D is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-13-8. Molecular formula: C25H33NO. Mole weight: 363.53.
Aurachin D
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108354-13-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7151.
Auramine O Certified ≥95% (Dye content)
Auramine O Certified ≥95% (Dye content). Group: Biochemicals. Grades: Certified Dye. CAS No. 2465-27-2. Pack Sizes: 250g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences.
Worldwide
Auramine O (For Biological Stains and Dyes)
Auramine O (For Biological Stains and Dyes). Uses: For analytical and research use. Alternative Names: Auramine hydrochloride; Basic yellow 2; Pyocatanium aureum; Aizen auramine; Pyoktanin yellow. CAS No. 2465-27-2. Molecular formula: C17H22ClN3. Mole weight: 303.8. IUPAC Name: 4-[4-(dimethylamino)benzenecarboximidoyl]-N,N-dimethylaniline;hydrochloride. Catalog: APB2465272.
Auramine O, technicaL grade
Auramine O, technicaL grade. Group: Biochemicals. Grades: Purified. CAS No. 2465-27-2. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences.
Worldwide
Auramycin A
It is produced by the strain of Streptomyces galilaeus. Auramycin has the ability of anti gram-positive bacteria and tumor, with the LD50 100mg/kg (Mouse, abdominal cavity). Synonyms: methyl (1R,2R,4S)-4-[(2S,4S,5S,6S)-4-dimethylamino-5-[(2S,4S,5R,6S)-4- hydroxy-6-methyl-5-[(2S,6S)-6-methyl-5-oxo-oxan-2-yl]oxy-oxan-2-yl]oxy -6-methyl-oxan-2-yl]oxy-2,5,7-trihydroxy-2-methyl-6,11-dioxo-3,4-dihyd ro-1H-tetracene-1-carboxylate; auramycin A. Grade: 95%. CAS No. 78173-92-9. Molecular formula: C41H51NO15. Mole weight: 797.84.
Auramycin B
It is produced by the strain of Streptomyces galilaeus. Auramycin has the ability of anti gram-positive bacteria and tumor, with the LD50 100mg/kg (Mouse, abdominal cavity). Synonyms: auramycin B. CAS No. 78173-91-8. Molecular formula: C41H49NO15. Mole weight: 795.83.
Auranofin
Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Synonyms: SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D. Grade: ≥98%. CAS No. 34031-32-8. Molecular formula: C20H34AuO9PS. Mole weight: 678.49.
Auranofin
Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2?μM for monkey kidney Vero E6 cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-39162. CAS No. 34031-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1123.
Auranofin-13C6
Auranofin-13C6 is a labelled analogue of Auranofin, a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase. Synonyms: [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold-13C6; 2,3,4,6-Tetraacetate(1-thio-β-D-glucopyranosato)(triethylphosphine)-gold-13C6; Aktil-13C6; Auranofin-13C6; Crisinor-13C6; Crisofin-13C6; NSC 32152-13C6; Ridaura-13C6; Ridauran-13C6; SKF 39162-13C6; SKF 39162D-13C6; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold-13C6. Molecular formula: C14[13C]6H34AuO9PS. Mole weight: 684.44.
Auranofin 99+%
Auranofin 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences.
Aurantiamide is a non-covalent, orally active, blood-brain-permeable GRPR selective antagonist with anti-inflammatory and neuroprotective effects. Aurantiamide reduces inflammation and oxidative stress in renal tissue by inhibiting GRPR-mediated renal necrosis pathways (such as RIPK3/MLKL signaling) and NF-κB inflammatory pathways, exerting anti-acute kidney injury and endothelial function activities. Aurantiamide also inhibits the M1 polarization of microglia and inhibits NLRP3 activation, thereby improving AD mouse models. Aurantiamide has in vivo inhibitory efficacy in acute kidney injury models such as ischemia/reperfusion, sepsis, and hypertension models[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58115-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N2909.
Aurantiamide acetate
Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Asperglaucide. CAS No. 56121-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2905.
Aurantimycin A
Aurantimycin A is an antibiotic isolated from Streptomyces aurantiacus IMET 43917. Aurantimycin A has activity against Gram-positive bacteria and inhibits cell adhesion. Synonyms: Aurantimycin; NSC-777195; D-Alanine, (3S)-3-hydroxy-N-[(2R)-2-hydroxy-1-oxo-2-[(2S,5S,6S)-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-O-methyl-L-serylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-, (6→13)-lactone. Grade: ≥95%. CAS No. 162478-50-4. Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycin A
Depsipeptide antibiotic. Active against Gram-positive bacteria. Cytotoxic agent. Nematocide activity. Antiulcer agent. Anti-inflammatory drug (C5a antagonist). Group: Biochemicals. Grades: Highly Purified. CAS No. 162478-50-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Aurantimycinn A
Aurantimycinn A is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn A has strong anti-gram positive bacterial activity, with MIC 0.007-0.08μg/mL, which can be tolerated by mice 1mg/kg (intravenous), 250mg/kg (oral). Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycinn B
Aurantimycinn B is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn B has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H62N8O14. Mole weight: 854.94.
Aurantimycinn C
Aurantimycinn C is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn C has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H60N8O14. Mole weight: 852.93.
Aurantiogliocladin
It is produced by the strain of Gliocladium roseum. Aurantiogliocladin has weak activity of anti-gram positive bacteria, negative bacteria and fungal. Synonyms: 2,3-DIMETHOXY-5,6-DIMETHYL-2,5-CYCLOHEXADIENE-1,4-DIONE; 2,3-DIMETHOXY-5,6-DIMETHYL-P-BENZOQUINONE; AURANTIOGLIOCLADIN; 2,3-Dimethoxy-5,6-dimethyl-1,4-benzoquinone. Grade: 95%. CAS No. 483-54-5. Molecular formula: C10H12O4. Mole weight: 196.20.
Aurantiol
Aurantiol. CAS No. 89-43-0. Kosher: Y. VIGON Item # 500018. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers.
America & Internationally
Aurantioobtusin
Aurantioobtusin. Group: Biochemicals. Alternative Names: 1,3,7-Trihydroxy-2,8-dimethoxy-6-methyl-9,10-anthracenedione. Grades: Highly Purified. CAS No. 67979-25-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C17H14O7. US Biological Life Sciences.
Worldwide
Aurantio-obtusin
Aurantio-obtusin. Group: Biochemicals. Grades: Plant Grade. CAS No. 67979-25-3. Pack Sizes: 20mg. Molecular Formula: C17H14O7, Molecular Weight: 330.29. US Biological Life Sciences.
Worldwide
AurAP14
AurAP14 is an Aurora A PROTAC degrader (DC50 = 120 nM). AurAP14 shows significant inhibitory activity against various tumor cell lines, with IC50s of 0.294 μM in A549 cells and 0.534 μM in MCF-7 cells. AurAP14 induces apoptosis and arrests A549 cells in the S and G2/M phases. AurAP14 demonstrates anti-tumor efficacy in nude mouse xenograft models of A549 and A549/PTR. AurAP14can be used in the research on the treatment of Aurora A-overexpressing NSCLC. (Pink: Aurora A ligand (HY-10971), Blue: E3 ligase Ligand (HY-W437598), Black: Linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3106831-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-178472.
Auraptene
Auraptene. Group: Biochemicals. Alternative Names: 7-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one; 7-(Geranyloxy)-coumarin; 7-[(3,7-Dimethyl-2,6-octadienyl)oxy]-coumarin; (E)-7-Geranoxycoumarin; 7-Geranyloxycoumarin; Aurapten; Aurapten (C19H22O3); Auraptene. Grades: Highly Purified. CAS No. 495-02-3. Pack Sizes: 100mg. Molecular Formula: C19H22O3, Molecular Weight: 298.38. US Biological Life Sciences.
Worldwide
Auraptenol
Auraptenol is a natural coumarin found in the fruits of Citrus aurantium. It has antifibrotic activity and the anti-hyperalgesic action which may be as a novel analgesic for the management of neuropathic pain. Uses: Antifibrotic, anti-hyperalgesic. Synonyms: (+)-8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-1-benzopyran-2-one. Grade: >98%. CAS No. 1221-43-8. Molecular formula: C15H16O4. Mole weight: 260.3.
Aurein-1.1 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Synonyms: Gly-Leu-Phe-Asp-Ile-Ile-Lys-Lys-Ile-Ala-Glu-Ser-Ile-NH2; Aurein 1.1. Grade: ≥97%. Molecular formula: C68H116N16O18. Mole weight: 1445.77.
Aurein-1.2
Aurein-1.2 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Synonyms: H-Gly-Leu-Phe-Asp-Ile-Ile-Lys-Lys-Ile-Ala-Glu-Ser-Phe-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-isoleucyl-L-alanyl-L-alpha-glutamyl-L-seryl-L-phenylalaninamide; Aurein 1.2. Grade: ≥96%. Molecular formula: C71H114N16O18. Mole weight: 1479.78.
Aurein-2.1
Aurein-2.1 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 2.1; H-Gly-Leu-Leu-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Phe-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-phenylalanyl-glycyl-L-seryl-L-leucinamide. Grade: ≥96%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.2
Aurein-2.2 is an amphipathic alpha-helical antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Leu-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-leucyl-glycyl-L-seryl-L-leucinamide; Aurein 2.2. Grade: >97%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.3
Aurein-2.3 is an antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Ile-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-isoleucyl-glycyl-L-seryl-L-leucinamide; Aurein 2.3. Grade: ≥97%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.4
Aurein-2.4 is an amphipathic alpha-helical antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Thr-Ile-Ala-Gly-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-threonyl-L-isoleucyl-L-alanyl-glycyl-L-leucinamide; Aurein 2.4. Grade: ≥96%. Molecular formula: C77H133N19O19. Mole weight: 1629.03.
Aurein-2.5
Aurein-2.5 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 2.5; H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Phe-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-phenylalanyl-glycyl-L-seryl-L-leucinamide. Grade: >98%. Molecular formula: C79H129N19O19. Mole weight: 1649.02.
Aurein-2.6
Aurein-2.6 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 2.6; H-Gly-Leu-Phe-Asp-Ile-Ala-Lys-Lys-Val-Ile-Gly-Val-Ile-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-alanyl-L-lysyl-L-lysyl-L-valyl-L-isoleucyl-glycyl-L-valyl-L-isoleucyl-glycyl-L-seryl-L-leucinamide. Grade: ≥97%. Molecular formula: C77H133N19O19. Mole weight: 1629.03.
Aurein-3.1
Aurein-3.1 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 3.1; Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Ala-Gly-Ser-Ile-NH2. Grade: ≥97%. Molecular formula: C81H136N22O20. Mole weight: 1738.11.
Aurein-3.2
Aurein-3.2 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 3.2; H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Ala-Ser-Ser-Ile-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-isoleucyl-L-alanyl-glycyl-L-histidyl-L-isoleucyl-L-alanyl-L-seryl-L-seryl-L-isoleucinamide. Grade: ≥96%. Molecular formula: C82H138N22O21. Mole weight: 1768.14.
Aurein-3.3
Aurein-3.3 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Synonyms: Aurein 3.3; Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Val-Ser-Ser-Ile-NH2. Grade: ≥96%. Molecular formula: C84H142N22O21. Mole weight: 1796.19.
Aurein-5.2
Aurein-5.2 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial activity. Synonyms: Aurein 5.2; Gly-Leu-Met-Ser-Ser-Ile-Gly-Lys-Ala-Leu-Gly-Gly-Leu-Ile-Val-Asp-Val-Leu-Lys-Pro-Lys-Thr-Pro-Ala-Ser-OH. Grade: ≥96%. Molecular formula: C110H194N28O32S. Mole weight: 2452.98.
Aurelin
Aurelin is an antimicrobial peptide produced by Aurelia aurita (Moon jellyfish). It has antibacterial activity against the Gram-positive bacterium L.monocytogenes and the Gram-negative bacterium E.coli. Synonyms: Ala-Ala-Cys-Ser-Asp-Arg-Ala-His-Gly-His-Ile-Cys-Glu-Ser-Phe-Lys-Ser-Phe-Cys-Lys-Asp-Ser-Gly-Arg-Asn-Gly-Val-Lys-Leu-Arg-Ala-Asn-Cys-Lys-Lys-Thr-Cys-Gly-Leu-Cys (Disulfide bridge: Cys3-Cys33, Cys12-Cys37, Cys19-Cys40). Grade: >98%. Molecular formula: C176H284N60O54S6. Mole weight: 4296.93.
Aureobasidin A
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Basifungin. CAS No. 127785-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1975.
Aureobasidin A
Aureobasidin A is a cyclic depsipeptide antibiotic isolated from the filamentous fungus Aureobasidium pullulans R106. It is an antifungal agent that inhibits phosphorylceramide synthase. Synonyms: Basifungin. CAS No. 127785-64-2. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Aureobasidine A
Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Aureocin A53
Aureocin A53 is an antimicrobial peptide produced by Staphylococcus aureus A53. It has antibacterial activity against Gram-positive bacteria: Listeria monocytogenes, Staphylococcus simulans (MIC=100 nM), Staphylococcus aureus (MRSA), Streptococcus agalactiae, Micrococcus luteus (MIC=0.15 nM). Synonyms: N-formylmethionine-Ser-Trp-Leu-Asn-Phe-Leu-Lys-Tyr-Ile-Ala-Lys-Tyr-Gly-Lys-Lys-Ala-Val-Ser-Ala-Ala-Trp-Lys-Tyr-Lys-Gly-Lys-Val-Leu-Glu-Trp-Leu-Asn-Val-Gly-Pro-Thr-Leu-Glu-Trp-Val-Trp-Gln-Lys-Leu-Lys-Lys-Ile-Ala-Gly-Leu; aucA. Grade: >85%. Molecular formula: C292H447N69O66S. Mole weight: 6012.27.
aureolysin
A metalloenzyme from S. aureus earlier confused with staphylokinase (a non-enzymic activator of plasminogen). Group: Enzymes. Synonyms: Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Enzyme Commission Number: EC 3.4.24.29. CAS No. 39335-13-2. Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4310; aureolysin; EC 3.4.24.29; 39335-13-2; Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Cat No: EXWM-4310.
Aureoquinone
Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Synonyms: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20.
Aureothin
Aureothin is produced by the strain of Streptomyces thioluteus 4-A-1 and Streptomyces sp. 58. An unusual pyranone metabolite; has broad biological actions including antitumour, antimicrobial and insecticidal activities; a potent inhibitor of helicobacter pylori. Synonyms: Distacin; Mycolutein. Grade: >95% by HPLC. CAS No. 2825-00-5. Molecular formula: C29H26ClF3N2O6. Mole weight: 591.
Aureothin (Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K)
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibition of oxidoreductase. More recently Aureothin has been shown to be a potent inhibitor of Helicobacter pylori. Group: Biochemicals. Alternative Names: Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Aureothin (Mycolutein, Distacin, JA 2814K, Antibiotic 74A, BRN 0058476)
Oxidoreductase inhibitor. Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Aureothricin
Aureothricin. Group: Biochemicals. Alternative Names: Propionylpyrrothione. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H10N2O2S2. US Biological Life Sciences.
Worldwide
Aureothricin
Aureothricin is produced by the strain of Streptomyces celluloflavus. It was active against gram-positive bacteria, negative bacteria and Mycobacterium, and intraperitoneal injection could inhibit the increase of ascites in transplanted mice with Aldrin ascites carcinoma. Synonyms: Propionylpyrrothione; Farcinin. Grade: >98% by HPLC. CAS No. 574-95-8. Molecular formula: C9H10N2O2S2. Mole weight: 242.32.
Antibiotic. Active against Gram-positive and Gram-negative bacteria, yeast, filamentous fungi, protozoa and insects. Potent bacterial and yeast RNA polymerases inhibitor. Inhibitor of fungal mannan and glucan formation. Similar to thiolutin. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
Worldwide
Aureothricin (Propionylpyrrothione, Farcinin)
Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic analogue of thiolutin but has received only limited attention. Members of this class, notably, thiolutin, have been shown to potent inhibitors of bacterial and yeast RNA polymerases and inhibitors of mannan and glucan formation in fungi. Studies have shown that thiolutin inhibits tumor cell-induced angiogenesis in vivo. Group: Biochemicals. Alternative Names: Propionylpyrrothione, Farcinin. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug. US Biological Life Sciences.
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Aureusidin
Aureusidin. Group: Biochemicals. Alternative Names: (2Z) -2-[ (3, 4-dihydroxyphenyl) methylene]-4, 6-dihydroxy-3 (2H) -benzofuranone; Cernuin. Grades: Highly Purified. CAS No. 38216-54-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C15H10O6. US Biological Life Sciences.
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aureusidin synthase
A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4'-O-β-D-glucoside in vivo. Group: Enzymes. Synonyms: AmAS1. Enzyme Commission Number: EC 1.21.3.6. CAS No. 320784-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1253; aureusidin synthase; EC 1.21.3.6; 320784-48-3; AmAS1. Cat No: EXWM-1253.
Aureusimine B
It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grade: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29.
Auriclosene
Auriclosene is a potent and Broad spectrum antimicrobial agent. It is highly effective in in vitro studies against multi-drug resistant bacteria including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE). Phase III clinical trials for the treatment of Impetigo are on-going. Uses: Impetigo. Synonyms: NVC-422; NVC 422; NVC422; CD07223; CD-07223; CD 07223; Auriclosene. UNII-BKR7Y95229; 2-(dichloroamino)-2-methylpropane-1-sulfonic acid. Grade: 98%. CAS No. 846056-87-9. Molecular formula: C4H9Cl2NO3S. Mole weight: 222.08.
Auric sodium Chloride
Auric sodium Chloride. Alternative Names: Sodium tetrachloroaurate. CAS No. 15189-51-2. Purity: Au 48.0%. Product ID: ACM15189512. Molecular formula: NaAuCl4ยท2H2O. Mole weight: 397.8. Alfa Chemistry - ISO 9001:32057 Certified.
Auriculasin
Auriculasin is an anticancer agent that inhibits VEGFR2, PI3K/AKT/mTOR, MAPK. Auriculasin can inhibit cell proliferation, induce cell apoptosis, and inhibit angiogenesis, and promotes mitochondrial oxidative stress and ferroptosis. Auriculasin is also active at the cannabinoid receptor CB1 with an IC50 of 8.92 μM. Auriculasin can be used in cancer research, especially related diseases such as prostate cancer and non-small cell lung cancer, as well as research on the development of anti-angiogenic drugs[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60297-37-2. Pack Sizes: 1 mg. Product ID: HY-N2911.
Auriculasin
Auriculasin is a flavonoid derivative isolated from the herbs of Derris robusta. Synonyms: Cudraisoflavone A. Grade: 96%. CAS No. 60297-37-2. Molecular formula: C25H24O6. Mole weight: 420.5.
Aurin
Aurin. Group: Biochemicals. Alternative Names: p-Rosolic acid; 4-[Bis (4-hydroxyphenyl) methylene]-2, 5-cyclohexadienone. Grades: Highly Purified. CAS No. 603-45-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H14O3. US Biological Life Sciences.
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Aurintricarboxylic acid
Aurintricarboxylic acid acts as a histological dye and an insulin-like growth factor receptor 1 antagonist. Synonyms: 1,4-cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylen; aluminon free acid. Grade: 95%. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34.
Aurintricarboxylic acid
5g Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C22H14O9. CAS No. 4431-00-9. Prepack ID 21152979-5g. Molecular Weight 422.34. See USA prepack pricing.
Aurintricarboxylic acid ammonium salt (Aluminon)
100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C22H23N3O9. CAS No. 569-58-4. Prepack ID 28596801-100g. Molecular Weight 473.43. See USA prepack pricing.
Aurintricarboxylic acid trisodium salt
Aurintricarboxylic acid trisodium salt. Alternative Names: AURINTRICARBOXYLIC ACID TRISODIUM SALT;aurintricaboxylicacidtrisodiumsalt;c.i.mordantviolet39;c.i.mordantviolet39,trisodiumsalt;chromevioletg;mordantviolet39;trisodium 5,5-(3-carboxylato-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylate);5,5'-[[4-Oxo. CAS No. 13186-45-3. Product ID: ACM13186453. Molecular formula: C22H11Na3O9. Mole weight: 488.29. Alfa Chemistry - ISO 9001:32057 Certified.
Auristatin E
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Synonyms: Auristatin E. Grade: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01.
Auristatin E
Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160800-57-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-15582.