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| Product | Description | |
|---|---|---|
| Arbidol Sulfone | Arbidol Sulfone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylsulfonyl)methyl)-1H-indole-3-carboxylate. CAS No. 151455-32-2. Molecular formula: C22H25BrN2O5S. Mole weight: 509.41. Catalog: APB151455322. |  |
| Arbidol Sulfoxide | Arbidol Sulfoxide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylsulfinyl)methyl)-1H-indole-3-carboxylate. CAS No. 151455-33-3. Molecular formula: C22H25BrN2O4S. Mole weight: 493.41. Catalog: APB151455333. | |
| Arbidol Sulfoxide | A Impurity of Arbidol. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfinyl)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 151455-33-3. Molecular formula: C22H25BrN2O4S. Mole weight: 493.42. |  |
| Arborcandin A | Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397. Synonyms: 21,24-Bis(carbamoylmethyl)-15-(2-carbamoyl-2-hydroxyethyl)-9,12-bis(1-hydroxyethyl)-6-(3-hydroxydodecyl)-27-(8-hydroxydodecyl)-18-methyl-1,4,7,10,13,16,19,22,25,28-decaazacyclohentriacontane-2,5,8,11,14,17,20,23,26,29-decone. Molecular formula: C57H101N13O18. Mole weight: 1256.48. | |
| Arborcandin B | Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397. Synonyms: 21,24-Bis(carbamoylmethyl)-15-(2-carbamoyl-2-hydroxyethyl)-9,12-bis(1-hydroxyethyl)-6-(3-hydroxydodecyl)-27-(8-hydroxytridecyl)-18-methyl-1,4,7,10,13,16,19,22,25,28-decaazacyclohentriacontane-2,5,8,11,14,17,20,23,26,29-decone. Molecular formula: C58H103N13O18. Mole weight: 1270.51. | |
| Arborinine | Arborinine is an alkaloid isolated from Erthela bahiensis. Arborinine was shown to inhibit splenocytes proliferation under ConA or PWM stimulation and promote apoptosis on splenocytes and thymocytes stimulated with PWM in 24h. It also decreases production of Interleukin-10 by splenocytes and thymocytes stimulated with ConA or PWM. Synonyms: 1-hydroxy-2,3-dimethoxy-10-methylacridin-9-one. Grade: 98.5%. CAS No. 5489-57-6. Molecular formula: C16H15NO4. Mole weight: 285.299. | |
| Arborinine | Arborinine is a potent and orally activeLSD1 inhibitor. Arborinine increases the expression of H3K4me1/2, H3K9me1/2, E-cad protein and decreases the expression of UBE2O protein level. Arborinine induces cell cycle arrest at S phase. Arborinine shows antitumor activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Hydroxy-2,3-dimethoxy-10-methylacridin-9(10H)-one. Product Category: Inhibitors. CAS No. 5489-57-6. Mole weight: 285.29. Purity: 95%+. Product ID: ACM5489576. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Arbutamine | Arbutamine is β-adrenergic receptor originated by SICOR. It is a cardiac stimulant. Arbutamine is a synthetic catecholamine with positive chronotropic and inotropic properties and be applicated in echocardiography and diagnostic coronary angiography. Arbutamine can bind to and activate β-1 adrenergic receptors in the myocardium, so it can increase heart rate and force of myocardial contraction. Arbutamine is an approved drug for the treatment of Coronary artery disease. Uses: Coronary artery disease. Synonyms: Genesa; Arbutaminum; Arbutamina; UNII-B07L15YAEV; CHEBI:50580; ; 125251-66-3(Hydrochloride); 4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol. Grade: 98%. CAS No. 128470-16-6. Molecular formula: C18H23NO4. Mole weight: 317.38. | |
| Arbutin | Arbutin. Group: Biochemicals. Alternative Names: 4-Hydroxyphenyl- β-D-glucopyranoside; Arbutine; Arbutoside; Arbutyne; Hydroquinone Glucose; Hydroquinone β-D-Glucopyranoside; NSC 4036; Ursin; Uvasol; p-Arbutin; p-Hydroxyphenyl β-D-Glucopyranoside; p-Hydroxyphenyl β-D-Glucoside; β-Arbutin. Grades: Highly Purified. CAS No. 497-76-7. Pack Sizes: 10g. US Biological Life Sciences. |  Worldwide |
| Arbutin | Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase , with K i app values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi , possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Arbutin. CAS No. 497-76-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-N0192. |  |
| Arbutin | Arbutin. Synonyms: Hydroquinone-Beta-D-glucopyranoside. CAS No. 497-76-7. Product ID: CDC10-0032. Molecular formula: C12H16O7. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Arbutin; CDC10-0032; 497-76-7; C12H16O7; Hydroquinone-Beta-D-glucopyranoside; 207-850-3; MFCD00016915; 497-76-7. Purity: ≥98%. Color: White. EC Number: 207-850-3. Physical State: Powder. Solubility: H2O: 50 mg/mL hot, clear. Quality Level: 200. Storage: Inert atmosphere,Room Temperature. Application: Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Boiling Point: 375.31°C (rough estimate). Melting Point: 195 °C. Product Description: Arbutin is a derivative of hydroquinone used in skin-whitening ingredients. It is reported to inhibit the activity of tyrosinase, which is a key enzyme for melanin biosynthesis. This acts to effectively prevent the anomalous increase of melanin which is blamed for age or sun spots and freckles. |  |
| Arbutin | Arbutin is a glycosylated hydroquinone extracted from bearberry plant. Arbutin acts as an inhibitor of tyrosinase, and is used as a skin-lightening agent for the prevention of melanin formation in skin conditions. It is a good functional cosmetics material. Uses: Skin-lightening agent. Synonyms: 4-Hydroxyphenyl β-D-glucopyranoside; Hydroquinone-b-D-glucoside; Glucopyranoside, p-hydroxyphenyl, β-D-; Arbutine; Arbutoside; Arbutyne; Hydroquinone glucose; Hydroquinone β-D-glucopyranoside; NSC 4036; p-Arbutin; p-Hydroxyphenyl β-D-glucopyranoside; p-Hydroxyphenyl β-D-glucoside; Ursin; Uvasol; β-Arbutin. Grade: ≥98%. CAS No. 497-76-7. Molecular formula: C12H16O7. Mole weight: 272.25. | |
| Arbutin | Arbutin is a natural active substance derived from green plants. It combines the "green plant, safe and reliable" and "high-efficiency discoloration" into a skin decolorizing component, which can quickly penetrate into the skin without affecting cell proliferation. At the same time, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly combine with tyrosinase to accelerate the decompositio;n and excretion of melanin, thereby reducing skin pigmentation, eliminating pigmentation and Freckles, and do not produce toxic, irritating, sensitizing and other side effects on melanocytes, as well as bactericidal and anti-inflammatory effects. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Hydroxyphenyl-beta-D-glucopyranosid. Product Category: Material of cosmetics. Appearance: Solid. CAS No. 497-76-7. Molecular formula: C12H16O7. Mole weight: 272.25. Purity: 0.98. IUPACName: (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol. Canonical SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O. Density: 1.3582 g/cm³. ECNumber: 207-850-3. Product ID: ACM497767. Alfa Chemistry ISO 9001:2015 Certified. | |
| Arbutin-[13C6] | Arbutin-[13C6] is the labelled analogue of Arbutin, a glycosylated hydroquinone that can be extracted from bearberry plant. Arbutin is a known inhibitor of tyrosinase, which in turn prevents the formation of melanin. Arbutin is often used as a skin-lightening agent in cosmetic products. Synonyms: Arbutin-13C6; 4-Hydroxyphenyl-β-D-glucopyranoside-13C6; Arbutine-13C6; Arbutoside-13C6; Arbutyne-13C6; Hydroquinone Glucose-13C6; Hydroquinone β-D-Glucopyranoside-13C6; NSC 4036-13C6; Ursin-13C6; Uvasol-13C6; p-Arbutin-13C6; p-Hydroxyphenyl β-D-Glucopyranoside-13C6; p-Hydroxyphenyl β-D-Glucoside-13C6; β-Arbutin-13C6. Grade: >95%. Molecular formula: C6[13C]6H16O7. Mole weight: 278.21. | |
| Arbutin 99.5+% | Arbutin 99.5+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 5g. US Biological Life Sciences. | Worldwide |
| Arbutin > 99% HPLC | Arbutin > 99% HPLC. |  CA, FL & NJ |
| Arbutin (Standard) | Arbutin (Standard) is the analytical standard of Arbutin. This product is intended for research and analytical applications. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 497-76-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0192R. | |
| AR-C 102222 | AR-C 102222 has been found to be an iNOS inhibitor and show antinociceptive and anti-inflammatory activity in rodent pain models. Synonyms: AR-C 102222; AR C 102222; ARC 102222; ARC102222; 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride. Grade: ≥98% by HPLC. CAS No. 253771-21-0. Molecular formula: C19H16F2N6O.HCl. Mole weight: 418.83. | |
| AR-C102222 hydrochloride | AR-C102222 is a potent, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. Synonyms: 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile Hydrochloride (1:1). Grade: ≥98%. CAS No. 1781934-50-6. Molecular formula: C19H17ClF2N6O. Mole weight: 418.83. | |
| AR-C117977 | AR-C117977 is a potent MCT1 inhibitor that inhibited the rat MLR and was more potent than cyclosporin A (CsA). AR-C117977 can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. Synonyms: 5-((3-hydroxypropyl)thio)-1-isobutyl-3-methyl-6-(naphthalen-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C-117977; AR-C 117977. Grade: >98%. CAS No. 216685-07-3. Molecular formula: C25H28N2O3S2. Mole weight: 468.63. | |
| AR-C118925XX | AR-C118925XX is a selective P2Y2 receptor antagonist. AR-C118925XX inhibits ATP-induced IL-6 production and phosphorylation of p38. AR-C118925XX also inhibits Bleomycin (HY-108345)-induced dermal fibrosis in mice. AR-C118925XX also inhibits ATP-induced tumor growth[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216657-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110126. | |
| AR-C 118925XX | AR-C 118925XX. Group: Biochemicals. Grades: Purified. CAS No. 216657-60-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AR-C 118925XX | AR-C126313, a thiouracil derivative, has been found to be a competitive P2Y2 receptor antagonist and could inhibit P2Y2 receptor-induced β-arrestin translocation in vitro. Synonyms: AR-C126313; ARC126313; AR C126313; 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide. Grade: ≥97% by HPLC. CAS No. 216657-60-2. Molecular formula: C28H23N7O3S. Mole weight: 537.59. | |
| ARC12 | ARC12 is a secondary metabolism probe that modulates the production of Streptomyces coelicolor secondary metabolites. ARC12 reduces the production of germicidin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64433-38-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153611. | |
| AR-C124910XX-N-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C124910XX-O-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C141990 hydrochloride | AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pKi values of 7.6, 6.6 for MCT-1 and MCT-2, respectively. Synonyms: AR-C 141990 hydrochloride. CAS No. 2250019-94-2. Molecular formula: C26H29ClN4O4S. Mole weight: 529.05. | |
| AR-C155858 | AR-C155858. Group: Biochemicals. Alternative Names: (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-4-isoxazolidinol;(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C 155858. Grades: Highly Purified. CAS No. 496791-37-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AR-C155858 | AR-C155858 is a novel inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2, but exhibits no activity at MCT4. It can be used to probe MCTs' roles in the metabolic studies. Besides, AR-C155858 was found to have immunosuppressive activity and can inhibit the proliferation of T-lymphocytes. Synonyms: ARC155858; AR-C155858; ARC 155858. Grade: >98%. CAS No. 496791-37-8. Molecular formula: C21H27N5O5S. Mole weight: 461.53. | |
| AR-C155858 | AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with K i s of 2.3 nM and 10 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 496791-37-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13248. | |
| ARC 239 | ARC239 dihydrochloride is a potent and selective α2 B adrenoceptor antagonist. It is used as an α-adrenoceptor blocking drug. It competitively antagonizes pressor responses to adrenaline and inhibits pressor responses to noradrenaline, tyramine, phenylephrine and dimethylphenylpiperazinium. Uses: Arc239 dihydrochloride is used as an α-adrenoceptor blocking drug. Synonyms: ARC239 dihydrochloride; ARC 239 dihydrochloride; ARC-239 dihydrochloride; 2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride; AR-C239 Dihydrochloride. Grade: 98%. CAS No. 67339-62-2. Molecular formula: C24H29N3O3. Mole weight: 407.5. | |
| ARC 239 dihydrochloride | The hydrochloride salt form of ARC 239, which has been found to be an α2B adrenoceptor antagonist as well as a norepinephrine-serotonin reuptake inhibitor. Uses: Adrenergic alpha-antagonists. Synonyms: ARC 239 dihydrochloride; ARC239 dihydrochloride; ARC-239 dihydrochloride; 2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride. Grade: ≥98% by HPLC. CAS No. 55974-42-0. Molecular formula: C24H29N3O3.2HCl. Mole weight: 480.43. | |
| ARC 239 dihydrochloride hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AR-C 66096 tetrasodium salt | The sodium salt form of AR-C 66096, which has been found to be a P2Y12 receptor antagonist and could be probably used as an antithrombotic agent. Synonyms: ARL-66096; ARL 66096; ARL66096; 2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt. Grade: ≥98% by HPLC. CAS No. 145782-74-7. Molecular formula: C14H18F2N5Na4O12P3S. Mole weight: 703.26. | |
| ARC7 | ARC7 can act as a probe for secondary metabolism in S. coelicolor. ARC7 is a tool for studying secondary metabolism and the streptomycete life cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 681212-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153610. | |
| ARCA ammonium salt | m27,3'-OGP3G (ARCA Cap Analog) - solution is a valuable tool in the biomedical field, specifically in drug discovery and gene expression studies. m27,3'-OGP3G acts as an efficient cap analog, promoting mRNA capping reactions in various experimental settings. It finds applications in RNA synthesis, mRNA translation and cellular processes related to RNA metabolism. Its utility extends to investigating viral infections, cancer therapeutics and molecular biology research. Synonyms: ARCA Ammonium; Anti Reverse Cap Analog ammonium salt; m7(3'-O-methy)G(5')ppp(5')G ammonium salt; 3'-O-Me-m7G(5')ppp(5')G ammonium salt; m27, 3'-OGP3G (ARCA Cap Analog) ammonium salt; 3'-O-Methyl-m7GpppG ammonium salt; ARCA (anti-reverse cap analog) ammonium salt; m27,3'OGpppG ammonium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine ammonium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| Arcaine sulfate | Arcaine sulfate is the sulfate salt of arcaine, which is a potent, competitive and novel antagonist of the polyamine site on the NMDA receptor. Synonyms: N,N'-1,4-Butanediylbisguanidine sulfate; 1,4-Diguanidinobutane sulfate salt. Grade: ≥99% by HPLC. CAS No. 14923-17-2. Molecular formula: C6H18N6SO4. Mole weight: 270.31. | |
| Arcaine sulfate | Arcaine (sulfate) is a glutamate NMDA receptor inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14923-17-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100920. | |
| Arcaine Sulfate | Arcaine Sulfate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| ARCA Sodium | ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions. Synonyms: ARCA, sodium salt; Anti Reverse Cap Analog sodium salt; m7(3'-O-methy)G(5')ppp(5')G sodium salt; 3'-O-Me-m7G(5')ppp(5')G sodium salt; m27, 3'-OGP3G (ARCA Cap Analog) sodium salt; 3'-O-Methyl-m7GpppG sodium salt; ARCA (anti-reverse cap analog) sodium salt; m27,3'OGpppG sodium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine, sodium salt. Grade: ≥95% by HPLC. Molecular formula: C22H31N10O18P3 (free acid). Mole weight: 816.46 (free acid). | |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grade: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| ARCC-4 | ARCC-4 is a low-nanomolar Androgen Receptor (AR) degrader based on PROTAC, with a DC50 of 5?nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1973403-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130492. | |
| archaeosine | Archaeosine, an essential compound, holds immense significance in the realm of biomedicine due to its potential therapeutic efficacy in a diverse array of ailments. A pivotal player in crafting targeted medications for cancer, neurological maladies, and infectious conditions, this product assumes a critical role in the advanced pharmaceutical landscape. Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-b-D-ribofuranosyl-; 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide. CAS No. 148608-52-0. Molecular formula: C12H16N6O5. Mole weight: 324.3. | |
| archaeosine synthase | In Euryarchaeota the reaction is catalysed by ArcS. In Crenarchaeota, which do not have an ArcS homologue, the reaction is catalysed either by a homologue of EC 6.3.4.20, 7-cyano-7-deazaguanine synthase that includes a glutaminase domain (cf. EC 3.5.1.2), or by a homologue of EC 1.7.1.13, preQ1 synthase. The enzyme from the Euryarchaeon Methanocaldococcus jannaschii can also use arginine and ammonium as amino donors. Group: Enzymes. Synonyms: ArcS; TgtA2; MJ1022 (gene name); glutamine:preQ0-tRNA amidinotransferase (incorrect). Enzyme Commission Number: EC 2.6.1.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2938; archaeosine synthase; EC 2.6.1.97; ArcS; TgtA2; MJ1022 (gene name); glutamine:preQ0-tRNA amidinotransferase (incorrect). Cat No: EXWM-2938. |  |
| archaetidylinositol phosphate synthase | Requires Mg2+ or Mn2+ for activity. The enzyme is involved in biosynthesis of archaetidyl-myo-inositol, a compound essential for glycolipid biosynthesis in archaea. Group: Enzymes. Synonyms: AIP synthase. Enzyme Commission Number: EC 2.7.8.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3338; archaetidylinositol phosphate synthase; EC 2.7.8.39; AIP synthase. Cat No: EXWM-3338. | |
| archaetidylserine synthase | Requires Mn2+. Isolated from the archaeon Methanothermobacter thermautotrophicus. Group: Enzymes. Enzyme Commission Number: EC 2.7.8.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3337; archaetidylserine synthase; EC 2.7.8.38. Cat No: EXWM-3337. | |
| Arcitumomab | Arcitumomab is a humanized monoclonal antibody raised against human carcinoembryonic antigen (CEA). Arcitumomab is used as a diagnostic imaging agent for colorectal cancers. Synonyms: IMMU 4; CEA-Scan; Immunoglobulin G1, anti-(human carcinoembryonic antigen) Fab' fragment (mouse monoclonal IMMU-4 γ1-chain), disulfide with mouse monoclonal IMMU-4 light chain. Grade: 95%. CAS No. 154361-48-5. | |
| Arctigenin | Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral ( influenza A virus ) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Arctigenin. CAS No. 7770-78-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0035. | |
| Arctigenin | Arctigenin. Group: Biochemicals. Grades: Purified. CAS No. 7770-78-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Arctigenin 4'-O- β-gentiobioside | Arctigenin 4'-O- β-gentiobioside. Group: Biochemicals. Grades: Plant Grade. CAS No. 41682-24-0. Pack Sizes: 5mg. Molecular Formula: C33H44O16, Molecular Weight: 696.7. US Biological Life Sciences. | Worldwide |
| Arctiin | Arctiin. Group: Biochemicals. Grades: Plant Grade. CAS No. 20362-31-6. Pack Sizes: 20mg. Molecular Formula: C27H34O11, Molecular Weight: 534.55. US Biological Life Sciences. | Worldwide |
| Arctiin | Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in?ammatory cytokines levels. Arctiin can used in study glomerulonephritis [4] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Arctii; NSC 315527; Arctigenin-4-glucoside. CAS No. 20362-31-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0034. | |
| Arcyriaflavin A | Arcyriaflavin A is a potent dual target agent of calcium/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 4 (CDK4). Its IC50 values are 140 nM and 25 nM for CDK4 and CaMKII respectively, which is selective over protein kinase A (PKA) and PKC in vitro. It inhibits proliferation of HCT116 and NCI H460 human carcinoma cells and replication of human cytomegalovirus (HCMV) in vitro. It also inhibits proliferation and induces apoptosis of endometriotic cyst stromal cells (ECSCs). Synonyms: Arcyriaflavin A; Arcyriaflavin-A; 12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; Maleimide Indolocarbazole. Grade: ≥98% by HPLC. CAS No. 118458-54-1. Molecular formula: C20H11N3O2. Mole weight: 325.32. | |
| ARD1 | ARD1 is isolated from Archaeoprepona demophoon. It possesses potent anti-fungal activity. | |
| ARD-2128 | ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor degrader. It effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. Synonyms: ARD2128; ARD 2128; N-[(1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-4-[4-[[1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperidin-4-yl]methyl]piperazin-1-yl]benzamide. Grade: ≥98%. CAS No. 2222111-87-5. Molecular formula: C45H50ClN7O6. Mole weight: 820.37. | |
| ARD-2585 | ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer. Synonyms: Benzamide, N-[trans-4-[(3-chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]-; N-((1r,4r)-4-((3-chloro-4-cyanophenyl)(methyl)amino)cyclohexyl)-4-(4-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)azetidin-3-yl)piperazin-1-yl)benzamide; N-[trans-4-[(3-Chloro-4-cyanophenyl)methylamino]cyclohexyl]-4-[4-[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]-1-piperazinyl]benzamide; ARD 2585; ARD2585. CAS No. 2757422-79-8. Molecular formula: C41H43ClN8O5. Mole weight: 763.28. | |
| ARD-266 | ARD-266 is a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces the degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines (DC50s = 0.2-1 nM). Synonyms: 2-Pyrrolidinecarboxamide, N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-, (2S,4R)-; (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)ethynyl)piperidin-1-yl)-3-oxo-1-phenylpropyl)-4-hydroxy-1-((R)-3-methyl-2-(3-methylisoxazol-5-yl)butanoyl)pyrrolidine-2-carboxamide; (2S,4R)-N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethynyl]-1-piperidinyl]-3-oxo-1-phenylpropyl]-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-5-isoxazolyl)-1-oxobutyl]-2-pyrrolidinecarboxamide. Grade: ≥95%. CAS No. 2666951-70-6. Molecular formula: C52H59ClN6O7. Mole weight: 915.51. | |
| Ardeemin | Ardeemin is a heterocyclic compound produced by Aspergillus fischeri var. brasiliensis AB 1826 M-35. Aldamide has no antibacterial activity and has no effect on multidrug-resistant (MDR) tumor cells, but its acetylated compound 5-N-acetylaldamide can improve its effect on multidrug-resistant tumor cells. Molecular formula: C26H26N4O2. Mole weight: 426.51. | |
| Ardisiacrispin A | Ardisiacrispin A. Group: Biochemicals. Alternative Names: Saxifragifolin B; Deglucocyclamin I. Grades: Plant Grade. CAS No. 23643-61-0. Pack Sizes: 20mg. Molecular Formula: C52H84O22, Molecular Weight: 1061.21. US Biological Life Sciences. | Worldwide |
| Ardisicrenoside A | Ardisicrenoside A exhibits anti-cancer activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 160824-52-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8199. | |
| Ardisiphenol A | Ardisiphenol A. Group: Biochemicals. Alternative Names: 6-Pentadecyl-1,2,4-benzenetriol 1-Acetate. Grades: Highly Purified. CAS No. 387816-66-2. Pack Sizes: 1mg. Molecular Formula: C23H38O4, Molecular Weight: 378.55. US Biological Life Sciences. | Worldwide |
| ARE Activator, BTZO-1 (Macrophage Migration Inhibitory Factor Antagonist II, 2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one, MIF Antagonist II) | A cell-permeable benzothiazinone that is shown to interact with MIF homotrimer (=68.6nM and 157nM toward human and rat MIF, respectively, at pH 7.3) via the N-terminal proline in a pH-dependent manner, limiting its inhibitory capability against MIF tautomerase activity (13% inhibition at pH 6.0; [BTZO-1] = 30uM) due to reduced MIF binding at acidic pH. Shown to protect primary rat cardiomyocytes (330nM) from apoptotic death upon serum deprivation or DOX (200nM) treatment via activation of ARE- (antioxidant response element) mediated cytoprotective genes transcription in a MIF-dependent manner. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?N?OS, Molecular Weight: 240.3. US Biological Life Sciences. | Worldwide |
| Arecaidine | A metabolite of Arecoline, a cholinergic agonist. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid; 1,2,5,6-Tetrahydro-1-methyl-nicotinic Acid; Arecaine; N-Methylguvacine; NSC 76017. Grades: Highly Purified. CAS No. 499-04-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Arecaidine | Arecaidine, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine is a substrate of H + -coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 499-04-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2368. | |
| Arecaidine-d5 Hydrobromide | A labeled metabolite of Arecoline, a cholinergic agonist. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid-d5 Hydrobromide; 1,2,5,6-Tetrahydro-1-methylnicotinic Acid-d5 Hydrobromide; Arecaine-d5 Hydrobromide; N-Methylguvacine-d5 Hydrobromide; NSC 76017-d5 Hydrobromide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Arecaidine Ethyl Ester Hydrochloride | A Arecaidine derivative as muscarinic acetylcholine receptor binding. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Ethyl Ester Hydrochloride; 1,2,5,6-Tetrahydro-1-methylnicotinic Acid Ethyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 17210-50-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Arecaidine hydrochloride | Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H + -coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6018-28-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2368A. | |
| Arecaidine propargyl ester hydrobromide | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Arecaidine propargyl ester tosylate | Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist. It displays some selectivity for cardiac versus ileal M2 receptors. Synonyms: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate. CAS No. 147202-94-6. Molecular formula: C17H21NO5S. Mole weight: 351.42. | |
| Arecoline | Arecoline, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 63-75-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2364. | |
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