A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Avatrombopag Impurity 82. Uses: For analytical and research use. Alternative Names: 4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 1534575-19-3. Molecular formula: C7H4BrClN2S2. Mole weight: 293.87. Catalog: APB1534575193.
Avatrombopag Impurity 83
Avatrombopag Impurity 83. Uses: For analytical and research use. Alternative Names: 4-(thiophen-2-yl)thiazol-2-amine. CAS No. 28989-50-6. Molecular formula: C7H6N2S2. Mole weight: 182.27. Catalog: APB28989506.
Avatrombopag Impurity 84
Avatrombopag Impurity 84. Uses: For analytical and research use. Alternative Names: 4-(4-bromothiophen-2-yl)thiazol-2-amine. CAS No. 81216-89-9. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB81216899.
Avatrombopag Impurity 85
Avatrombopag Impurity 85. Uses: For analytical and research use. Alternative Names: 4-(5-bromothiophen-2-yl)thiazol-2-amine. CAS No. 34801-14-4. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB34801144.
Avatrombopag Impurity 86
Avatrombopag Impurity 86. Uses: For analytical and research use. Alternative Names: ethyl 1,2,3,6-tetrahydropyridine-4-carboxylate. CAS No. 40240-23-1. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB40240231.
Avatrombopag Impurity 87
Avatrombopag Impurity 87. Uses: For analytical and research use. Alternative Names: ethyl 1,2,3,4-tetrahydropyridine-4-carboxylate. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB03312.
Avatrombopag Impurity 88
Avatrombopag Impurity 88. Uses: For analytical and research use. Alternative Names: ethyl 2,3,4,5-tetrahydropyridine-4-carboxylate. Molecular formula: C8H13NO2. Mole weight: 155.19. Catalog: APB03313.
Avatrombopag Impurity 89
Avatrombopag Impurity 89. Uses: For analytical and research use. Alternative Names: 1-(4-cyclohexylpiperazin-1-yl)ethanone. CAS No. 91695-59-9. Molecular formula: C12H22N2O. Mole weight: 210.32. Catalog: APB91695599.
Avatrombopag Impurity 9
Avatrombopag Impurity 9. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate. CAS No. 570403-14-4. Molecular formula: C31H38Cl2N6O3S2. Mole weight: 677.71. Catalog: APB570403144.
Avatrombopag Impurity 90
Avatrombopag Impurity 90. Uses: For analytical and research use. Alternative Names: (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-2-yl)methanone. Molecular formula: C16H21Cl2N3O. Mole weight: 342.26. Catalog: APB03310.
Avatrombopag Impurity 91
Avatrombopag Impurity 91. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-6-(4-cyclohexylpiperazine-1-carbonyl)pyridin-2-yl)piperidine-4-carboxylate. Molecular formula: C24H35ClN4O3. Mole weight: 463.01. Catalog: APB03311.
Avatrombopag Impurity 92
Avatrombopag Impurity 92. Uses: For analytical and research use. Alternative Names: ethyl 1-(3-chloro-5-(4-cyclohexylpiperazine-1-carbonyl)pyridin-2-yl)piperidine-4-carboxylate. CAS No. 2948773-24-6. Molecular formula: C24H35ClN4O3. Mole weight: 463.01. Catalog: APB2948773246.
Avatrombopag Impurity 93
Avatrombopag Impurity 93. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(thiophen-2-yl)thiazol-2-amine. CAS No. 81216-84-4. Molecular formula: C7H5BrN2S2. Mole weight: 261.16. Catalog: APB81216844.
Avatrombopag Impurity 94
Avatrombopag Impurity 94. Uses: For analytical and research use. Alternative Names: 5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-amine. Molecular formula: C17H24N4S2. Mole weight: 348.53. Catalog: APB03309.
Avatrombopag Impurity 95
Avatrombopag Impurity 95. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(4-bromothiophen-2-yl)thiazol-2-amine. Molecular formula: C7H4Br2N2S2. Mole weight: 340.06. Catalog: APB03308.
Avatrombopag Impurity 96
Avatrombopag Impurity 96. Uses: For analytical and research use. Alternative Names: 4-(4-bromothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine. CAS No. 570407-44-2. Molecular formula: C17H23BrN4S2. Mole weight: 427.43. Catalog: APB570407442.
Avatrombopag Impurity 97
Avatrombopag Impurity 97. Uses: For analytical and research use. Alternative Names: 5-bromo-4-(5-bromothiophen-2-yl)thiazol-2-amine. CAS No. 81216-88-8. Molecular formula: C7H4Br2N2S2. Mole weight: 340.06. Catalog: APB81216888.
Avatrombopag Impurity 98
Avatrombopag Impurity 98. Uses: For analytical and research use. Alternative Names: 4-(5-bromothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine. CAS No. 570407-27-1. Molecular formula: C17H23BrN4S2. Mole weight: 427.43. Catalog: APB570407271.
Avatrombopag Impurity 99
Avatrombopag Impurity 99. Uses: For analytical and research use. Alternative Names: 1,4-dicyclohexylpiperazine. CAS No. 19982-04-8. Molecular formula: C16H30N2. Mole weight: 250.42. Catalog: APB19982048.
Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. CAS No. 677007-74-8. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7.
Avatrombopag maleate
Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AKR-501 maleate; E5501 maleate; YM477 maleate. CAS No. 677007-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-13463A.
Avatrombopag (Maleate)
Avatrombopag (Maleate). Uses: For analytical and research use. Alternative Names: 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid compound with maleic acid (1:1). CAS No. 677007-74-8. Molecular formula: C29H34Cl2N6O3S2·C4H4O4. Mole weight: 765.72. Catalog: APB677007748.
Avatrombopag Meleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Category: Other apis. Synonyms: E5501 MALEATE. UNII-GDW7M2P1IS. GDW7M2P1IS. CAS No. 677007-74-8. Product ID: API677007748. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. EINECS: 973-683-4. SMILES: C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl.C(=CC(=O)O)C(=O)O.
AvBD10
AvBD10 is an antimicrobial peptide produced by liver, Peking duck, Anas platyrhynchos (Domestic duck). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Duck AvBD10; Duck avian beta defensin 10; Val-Leu-Leu-Phe-Leu-Phe-Gln-Ala-Ala-Pro-Gly-Ser-Ala-Asp-Ala-Pro-Phe-Ala-Asp-Thr-Ala-Ala-Cys-Arg-Ser-Gln-Gly-Asn-Phe-Cys-Arg-Ala-Gly-Ala-Cys-Pro-Pro-Thr-Phe-Ala-Ala-Ser-Gly-Ser-Cys-His-Gly-Gly-Leu-Leu-Asn-Cys-Cys-Ala-Lys. Grade: >98%.
AVB-S6-500
AVB-S6-500 is a GAS6-AXL signaling pathway blocker with high affnity for GAS6. AVB-S6-500 is developed for the treatment of cancer and nonmalignant fibrotic conditions as a drug candidate. It is in a phase I clinical trial for its safety and tolerability study. Uses: Potential treatment of cancer and nonmalignant fibrotic conditions. Synonyms: Aravive-S6.
Avdoralimab
Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450.
AVE-0118
AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grade: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57.
AVE 0118 hydrochloride
AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grade: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03.
AVE 0991
AVE 0991 is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: 1-ethyl-3-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea5-formyl-4-methoxy-2-phenyl-1-((4-(2-ethyl-aminocarbonylsulfonamido-5-isobutyl-3-thienyl)phenyl)methyl)imidiazoleAVE 0991; AVE-0991; AVE0991. CAS No. 304462-19-9. Molecular formula: C29H32N4O5S2. Mole weight: 580.72.
AVE 0991 sodium salt
AVE 0991 sodium salt, is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: AVE-0991 sodium salt; AVE 0991 sodium salt; AVE0991 sodium salt; sodium; ethylcarbamoyl-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylazanideAVE 0991 (sodium salt)306288-04-0C29H31N4NaO5S23195AH. CAS No. 306288-04-0. Molecular formula: C29H31N4NaO5S2. Mole weight: 602.70.
AVE5688
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes. Uses: Scientific research. Category: Signaling pathways. CAS No. 613260-13-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100320.
AVE-8063
AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity. Synonyms: AVE8063; AVE 8063; (Z)-1-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl) aniline. Grade: >98%. CAS No. 162705-07-9. Molecular formula: C18H21NO4. Mole weight: 315.37.
AVE-8134
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively. Synonyms: AVE8134; 2-Methyl-6-((3-((2-phenyloxazol-4-yl)methoxy)propoxy)methyl)benzoic acid. CAS No. 304025-09-0. Molecular formula: C22H23NO5. Mole weight: 381.42.
Avelumab
Avelumab (Anti-Human PD-L1) a fully human IgG1 anti-PD-L1 monoclonal antibody (mAb) with potential antibody-dependent cell-mediated cytotoxicity (ADCC). Avelumab enhances ADCC on several cancer cell lines expressing PD-L1. Avelumab can be used for the study of chordoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730.
Avelumab (anti-PD-L1)
Avelumab (anti-PD-L1) a fully human IgG1 anti-PD-L1 monoclonal antibody (mAb) with potential antibody-dependent cell-mediated cytotoxicity (ADCC). Avelumab (anti-PD-L1) enhances ADCC on several cancer cell lines expressing PD-L1. Avelumab (anti-PD-L1) can be used for the study of chordoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108730A.
Avenaciolide
It is produced by the strain of Aspergillus avenaceus. A bicyclic bis-butyrolactone; isolated from aspergillus avenaceu; an antifungal agent; inhibits glutamate transport; an atypical ionophore. Synonyms: Avenaciolid; Furo(3,4-b)furan-2,6(3H,4H)-dione, dihydro-3-methylene-4-octyl- (VAN) (8CI). Grade: >95% by HPLC. CAS No. 20223-76-1. Molecular formula: C15H22O4. Mole weight: 266.33.
avenacosidase
Isolated from oat (Avena sativa) seedlings. The product acts as a defense system against fungal infection. Also acts on avenacoside A. Group: Enzymes. Synonyms: As-P60. Enzyme Commission Number: EC 3.2.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3872; avenacosidase; EC 3.2.1.188; As-P60. Cat No: EXWM-3872.
Avenalumic acid
Avenalumic acid. Alternative Names: (2E,4E)-5-(4-Hydroxyphenyl)-2,4-pentadienoic Acid. CAS No. 135754-92-6. Product ID: FFC-AR-135754926. Molecular formula: C11H10O3. Mole weight: 190.2. IUPAC Name: (2E,4E)-5-(4-hydroxyphenyl)penta-2,4-dienoic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Avenanthramide C
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimers disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 116764-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124344.
Avenanthramide-C methyl ester
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 = 40 μM). Synonyms: Avenanthramide-C methyl ester; 955382-52-2; methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate; SCHEMBL20963041; IUZHCICFVDHVMC-XVNBXDOJSA-N; AKOS040755114; Methyl (E)-2-(3-(3,4-dihydroxyphenyl)acrylamido)-5-hydroxybenzoate; 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxy-benzoic acid, methyl ester; 2-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxybenzoic acid, methyl ester. Grade: ≥90%. CAS No. 955382-52-2. Molecular formula: C17H15NO6. Mole weight: 329.3.
Avenanthramide D
Avenanthramide D is a multifaceted bioactive compound with antioxidant, anti-inflammatory and cardiovascular protective effects used in studying diabetes, cancer and cardiovascular disorders. Synonyms: Avenanthramide 1p; Dianthramide P; N-p-Coumarylanthranilic acid; N-(E)-p-Coumaroylanthranilic acid. CAS No. 115610-36-1. Molecular formula: C16H13NO4. Mole weight: 283.28.
Avenciguat
Avenciguat (BI-685509) is a potent and orally active sGC activator. Avenciguat restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. Avenciguat can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI-685509. CAS No. 1579514-06-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153092.
Averantin
Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grade: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37.
Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5803-62-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
averantin hydroxylase
A heme-thiolate (P-450) monooxygenase isolated from Aspergillus parasiticus. There is no reaction with (1'R)-averantin. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Enzyme Commission Number: EC 1.14.13.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0772; averantin hydroxylase; EC 1.14.13.174; AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Cat No: EXWM-0772.
Avermectin A1a
Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10.
Avermectin A2a
Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12.
Avermectin B1
Avermectin B1. Group: Biochemicals. Grades: Highly Purified. CAS No. 71751-41-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C49H74O14. US Biological Life Sciences.
Worldwide
Avermectin B1a
Avermectin B1a. Group: Biochemicals. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C48H72O14. US Biological Life Sciences.
Worldwide
Avermectin B1a
It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Synonyms: Ivermectin EP Impurity A; Abamectin B1a; Doramectin Impurity 3. Grade: ≥95%. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08.
Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a)
Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical product. Group: Biochemicals. Alternative Names: 5-O-Demethylavermectin A1a, Antibiotic C 076B1a. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Avermectin B1a aglycone
It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grade: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74.
Avermectin b1a ≥95% (HPLC)
Avermectin b1a ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences.
Worldwide
Avermectin B1a monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grade: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91.
Avermectin B1b
Avermectin B1b is the minor component of the commercially available anthelmintic marketed as Abamectin. It is used broadly against nematodes, ticks, flies, and ants. Synonyms: Ivermectin EP Impurity B; 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-avermectin A1a; Doramectin Impurity 2. Grade: ≥95%. CAS No. 65195-56-4. Molecular formula: C47H70O14. Mole weight: 859.05.
Avermectin B1b (Antibiotic C 076B1b)
Avermectin B1b is the minor component (<20%) of the commerically available anthelmintic marketed as Abamectin(R) used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 24-position. In vitro and in vivo studies have shown this analogue to be active but less potent than the B1a analogue. Group: Biochemicals. Alternative Names: Antibiotic C 076B1b. Grades: Highly Purified. CAS No. 65195-56-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Avermectin B2a
Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Ivermectin EP Impurity C; (23S)-5-O-demethyl-23-hydroxy-22,23-dihydro-avermectin A1a. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09.
avermitilol synthase
Requires Mg2+. The recombinent enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol. The (1S)-hydrogen of farnesyl diphosphate is retained. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5260; avermitilol synthase; EC 4.2.3.96. Cat No: EXWM-5260.
Averufin
Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Synonyms: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34.
Avian Eggshell Membrane Collagen
Avian Eggshell Membrane Collagen.
CA, FL & NJ
Avibactam
Avibactam is a novel investigational non-beta-lactam beta-lactamase inhibitor that is being developed for possible use in combination with ceftaroline in the U.S. Avibactam does not have any intrinsic antibacterial activity in its own right, but appears to be capable of inhibiting beta-lactamase enzymes that belong to molecular classes A and C.Avibactam is useful for Antibiotics. Uses: Beta-lactamase inhibitors. Synonyms: Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester; Avibactam free acid; [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate. Grade: >98%. CAS No. 1192500-31-4. Molecular formula: C7H11N3O6S. Mole weight: 265.24.
Avibactam free acid
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXL-104 free acid. CAS No. 1192500-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14879.
Avibactam Impurity 11
Avibactam Impurity 11 is an impurity of Avibactam. Synonyms: Avibactam Impurity 11; 1416134-60-5; Ethyl 5-phenylmethoxyiminopiperidine-2-carboxylate; Avibactam Impurity 15; (S,E)-ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate. Grade: > 95%. CAS No. 1416134-60-5. Molecular formula: C14H18N2O3. Mole weight: 262.31.
Avibactam Impurity 13
Avibactam Impurity 13. Uses: For analytical and research use. CAS No. 2243810-78-6. Molecular formula: C6H13N3O5S. Mole weight: 239.25. Catalog: APB2243810786.
Avibactam Impurity 2
Avibactam Impurity 2. Uses: For analytical and research use. CAS No. 2064219-25-4. Molecular formula: C7H11N3O6S. Mole weight: 265.24. Catalog: APB2064219254.
Avibactam Impurity 25
Avibactam Impurity 25. Uses: For analytical and research use. Alternative Names: Avibactam Impurity 25. Molecular formula: C15H27NO6S. Mole weight: 349.44. Catalog: APB02734.
Avibactam Impurity 27
Avibactam Impurity 27. Uses: For analytical and research use. Alternative Names: (2S,5R)-ethyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate. CAS No. 1416134-48-9. Molecular formula: C17H24N2O7. Mole weight: 368.38. Catalog: APB1416134489.
Avibactam Impurity 28
Avibactam Impurity 28. Uses: For analytical and research use. Alternative Names: (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. CAS No. 1192651-49-2. Molecular formula: C14H17N3O3. Mole weight: 275.3. Catalog: APB1192651492.
Avibactam Impurity 29
Avibactam Impurity 29. Uses: For analytical and research use. Alternative Names: tetrabutylammonium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. CAS No. 1192651-80-1. Molecular formula: C23H46N4O6S. Mole weight: 506.7. Catalog: APB1192651801.