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| Product | Description | |
|---|---|---|
| Avibactam Impurity L (Avibactam Impurity 27) | Avibactam Impurity L (Avibactam Impurity 27). Uses: For analytical and research use. Molecular formula: C20H29ClN2O5. Mole weight: 412.91. Catalog: APB06723. |  |
| Avibactam Impurity M | Avibactam Impurity M. Uses: For analytical and research use. Alternative Names: (S,Z)-ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate. Molecular formula: C15H20N2O3. Mole weight: 276.33. Catalog: APB02740. | |
| Avibactam Impurity N | Avibactam Impurity N. Uses: For analytical and research use. Alternative Names: (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxamide. CAS No. 1416134-49-0. Molecular formula: C13H19N3O2. Mole weight: 249.31. Catalog: APB1416134490. | |
| Avibactam Impurity O | Avibactam Impurity O. Uses: For analytical and research use. Alternative Names: (2R,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. Molecular formula: C14H17N3O3. Mole weight: 275.3. Catalog: APB02739. | |
| Avibactam Impurity P | Avibactam Impurity P. Uses: For analytical and research use. Alternative Names: (2S,5S)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. CAS No. 2064219-16-3. Molecular formula: C14H17N3O3. Mole weight: 275.30. Catalog: APB2064219163. | |
| Avibactam Impurity R | Avibactam Impurity R. Uses: For analytical and research use. Alternative Names: 2243810-78-6(free base); sodium ((3R,6S)-6-carbamoylpiperidin-3-yl)amino sulfate. Molecular formula: C6H12N3O5S·Na. Mole weight: 261.23. Catalog: APB02738. | |
| Avibactam Impurity R (Avibactam Impurity 28 | Avibactam Impurity R (Avibactam Impurity 28. Uses: For analytical and research use. Molecular formula: C6H12N3NaO5S. Mole weight: 261.23. Catalog: APB06722. | |
| Avibactam Impurity S | Avibactam Impurity S. Uses: For analytical and research use. Alternative Names: sodium (2S,5R)-7-oxo-2-(sulfonatocarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. Molecular formula: C7H9N3Na2O9S2. Mole weight: 389.2. Catalog: APB02737. | |
| Avibactam Impurity S (Avibactam Impurity 29) | Avibactam Impurity S (Avibactam Impurity 29). Uses: For analytical and research use. Molecular formula: C7H9N3Na2O9S2. Mole weight: 389.26. Catalog: APB06725. | |
| Avibactam Impurity T | Avibactam Impurity T. Uses: For analytical and research use. Alternative Names: sodium (2R,5S)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. CAS No. 1383814-68-3. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. Catalog: APB1383814683. | |
| Avibactam Impurity U | Avibactam Impurity U. Uses: For analytical and research use. Alternative Names: sodium (2R,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. CAS No. 1797133-98-2. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. Catalog: APB1797133982. | |
| Avibactam Impurity V | Avibactam Impurity V. Uses: For analytical and research use. Alternative Names: sodium (2S,5S)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. CAS No. 2064219-26-5. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. Catalog: APB2064219265. | |
| Avibactam Impurity W | Avibactam Impurity W. Uses: For analytical and research use. Alternative Names: (2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. Molecular formula: C7H11N3O3. Mole weight: 185.18. Catalog: APB02735. | |
| Avibactam Impurity X | Avibactam Impurity X. Uses: For analytical and research use. Alternative Names: sodium (S,Z)-5-((tert-butoxycarbonyl)amino)-6-ethoxy-1-(iodo-dimethylsulfinyl)-6-oxohex-1-en-2-olate. Molecular formula: C15H27INNaO6S. Mole weight: 499.34. Catalog: APB02736. | |
| Avibactam sodium | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H10N3O6S ·Na. CAS No. 1192491-61-4. Prepack ID 90023818-100mg. Molecular Weight 287.2. See USA prepack pricing. |  |
| Avibactam sodium | Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXL-104. CAS No. 1192491-61-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879A. |  |
| Avibactam Sodium, (+)- | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Synonyms: (2R,5S)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo(3.2.1)octane-2-carboxamide monosodium salt. Grade: ≥95%. CAS No. 1383814-68-3. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. |  |
| Avibactam sodium hydrate | Avibactam is a reversible β-lactamase inhibitor (IC50 = 8/80/38 nM for TEM-1/P99/KPC-2 β-lactamases). Synonyms: NXL-104 hydrate. Molecular formula: C7H12N3NaO7S. Mole weight: 305.24. | |
| Avibactam sodium hydrate | Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXL-104 hydrate. CAS No. 2938989-90-1. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879B. | |
| Avibactam sodium Impurity CEA | Avibactam sodium Impurity CEA. Uses: For analytical and research use. Alternative Names: sodium ((3R,6S)-6-carbamoylpiperidin-3-yl)(ethoxycarbonyl)amino sulfate. Molecular formula: C9H16N3NaO7S. Mole weight: 333.29. Catalog: APB02723. | |
| Avibactam sodium Impurity CES | Avibactam sodium Impurity CES. Uses: For analytical and research use. Alternative Names: sodium ((3R,6S)-6-carbamoyl-1-(ethoxycarbonyl)piperidin-3-yl)amino sulfate. Molecular formula: C9H16N3NaO7S. Mole weight: 333.29. Catalog: APB02724. | |
| Avibactam sodium Impurity CIA | Avibactam sodium Impurity CIA. Uses: For analytical and research use. Alternative Names: sodium ((3R,6S)-6-carbamoylpiperidin-3-yl)(isopropoxycarbonyl)amino sulfate. Molecular formula: C10H18N3NaO7S. Mole weight: 347.32. Catalog: APB02720. | |
| Avibactam sodium Impurity CIS | Avibactam sodium Impurity CIS. Uses: For analytical and research use. Alternative Names: sodium ((3R,6S)-6-carbamoyl-1-(isopropoxycarbonyl)piperidin-3-yl)amino sulfate. Molecular formula: C10H18N3NaO7S. Mole weight: 347.32. Catalog: APB02722. | |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Synonyms: sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium. CAS No. 1192491-61-4. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. | |
| Avibactam sodium (Standard) | Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NXL-104 (Standard). CAS No. 1192491-61-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14879AR. | |
| Avibatan genotoxic Impurity 1 | Avibatan genotoxic Impurity 1. Uses: For analytical and research use. Molecular formula: C8H13N3O6S. Mole weight: 279.27. Catalog: APB06726. | |
| Avibatan genotoxic Impurity 2 | Avibatan genotoxic Impurity 2. Uses: For analytical and research use. Molecular formula: C9H15N3O6S. Mole weight: 293.29. Catalog: APB06728. | |
| Avibatan genotoxic Impurity 3 | Avibatan genotoxic Impurity 3. Uses: For analytical and research use. Molecular formula: C10H17N3O6S. Mole weight: 307.32. Catalog: APB06727. | |
| Avicularin | Avicularin. Group: Biochemicals. Alternative Names: Avicularoside; Fenicularin. Grades: Plant Grade. CAS No. 572-30-5. Pack Sizes: 20mg. Molecular Formula: C20H18O11, Molecular Weight: 434.35. US Biological Life Sciences. |  Worldwide |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Synonyms: Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside. Grade: >98%. CAS No. 572-30-5. Molecular formula: C20H18O11. Mole weight: 434.4. | |
| Avidin, chiken egg white | Avidin, chicken egg white is a glycoprotein derived from egg protein. Avidin, chicken egg white has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1405-69-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-NP005. | |
| Avidinorubicin | Avidinorubicin is produced by the strain of Streptomyces avidinii. It has anti-gram positive and negative bacterial activity, and has cytotoxicity to tumor cells. Molecular formula: C60H86N4O22. Mole weight: 1215.34. | |
| Aviglycine hydrochloride | Aviglycine hydrochloride (ABG-3168) is an inhibitor of ethylene biosynthesis. The use of Aviglycine hydrochloride (ABG-3168) delays the natural flowering of pineapples, reduces fruit drop, and maintains fruit firmness[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABG-3168. CAS No. 55720-26-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W009861. | |
| Avilamycin | Avilamycin is an antimicrobial agent that is active mainly against Gram-positive bacteria and is used against methicillin-resistant staphylococcus. Uses: Anti-bacterial agents. Synonyms: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax; (2R,3S,4R,6S)-6-(((3a'R,4R,4'R,5S,6R,6'S,7a'R)-6'-(((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5S,6S)-6-(((2R,3aS,3a'R,6S,6'R,7R,7aR,7'S,7a'R)-7'-acetyl-7'-hydroxy-7-(isobutyryloxy)-6'-methyloctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl)oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-4',6,7a'-trimethyloctahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-5-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate. Grade: > 95%. CAS No. 11051-71-1. Molecular formula: C61H88Cl2O32. Mole weight: 1404.24. | |
| Avilamycin (~80%) | Avilamycin is an antimicrobial agent used against methicillin resistant Staphylococcus. Group: Biochemicals. Alternative Names: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax. Grades: Highly Purified. CAS No. 11051-71-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1404.24. US Biological Life Sciences. | Worldwide |
| Avilamycin A | Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23. | |
| Avilamycin B | Avilamycin B is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Grade: 95%. CAS No. 73240-30-9. Molecular formula: C59H84Cl2O32. Mole weight: 1376.19. | |
| Avilamycin C | Avilamycin C is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Synonyms: SCHEMBL6753731. Grade: 95%. CAS No. 69787-80-0. Molecular formula: C61H90Cl2O32. Mole weight: 1406.25. | |
| Avimopan impurity 10 | Avimopan impurity 10. Uses: For analytical and research use. Molecular formula: C24H30N2O4. Mole weight: 410.51. Catalog: APB06656. | |
| Avimopan impurity 11 | Avimopan impurity 11. Uses: For analytical and research use. Molecular formula: C25H36N2O6. Mole weight: 460.57. Catalog: APB06658. | |
| Avimopan impurity 5 | Avimopan impurity 5. Uses: For analytical and research use. Molecular formula: C14H21NO. Mole weight: 219.33. Catalog: APB06651. | |
| Avimopan impurity 6 | Avimopan impurity 6. Uses: For analytical and research use. Molecular formula: C25H31BrN2O4. Mole weight: 503.44. Catalog: APB06655. | |
| Avimopan impurity 7 | Avimopan impurity 7. Uses: For analytical and research use. Molecular formula: C17H28ClNO. Mole weight: 297.87. Catalog: APB06654. | |
| Avimopan impurity 8 | Avimopan impurity 8. Uses: For analytical and research use. Molecular formula: C23H29NO3. Mole weight: 367.49. Catalog: APB06657. | |
| Avimopan impurity 9 | Avimopan impurity 9. Uses: For analytical and research use. CAS No. 2280857-23-8. Molecular formula: C25H32N2O4. Mole weight: 424.54. Catalog: APB2280857238. | |
| Aviptadil | Aviptadil is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine). CAS No. 40077-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0012. | |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Synonyms: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. Grade: 98%. CAS No. 40077-57-4. Molecular formula: C147H238N44O42S. Mole weight: 3325.80. | |
| Aviptadil acetate | Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vasoactive Intestinal Peptide acetate salt (human, rat, mouse, rabbit, canine, porcine). CAS No. 1444827-29-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0012A. | |
| Avitinib | Avitinib (AC0010) is a third generation inhibitor of the EGFR (epidermal growth factor receptor) that was permitted parallel phase I clinical trials in the US. It is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations. Upon oral administration, avitinib covalently binds to and inhibits the activity of mutant forms of EGFR. Uses: Tyrosine kinase inhibitors. Synonyms: AC0010. Grade: ≥98%. CAS No. 1557267-42-1. Molecular formula: C26H26FN7O2. Mole weight: 487.5. | |
| Avitinib | Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Abivertinib; AC0010. CAS No. 1557267-42-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19816. | |
| Avitinib maleate | Avitinib maleate, the maleate salt form of avitinib, is a pyrrolopyrimidine-based, irreversible epidermal growth factor receptor (EGFR) mutant-selective inhibitor (IC50 = 7.68 nM), with potential antineoplastic activity. Uses: Tyrosine kinase inhibitors. Synonyms: Avitinib maleate; AC0010MA; AC-0010MA; AC 0010MA; AC0010; AC-0010; AC 0010. CAS No. 1557268-88-8. Molecular formula: C30H30FN7O6. Mole weight: 603.6. | |
| Avitotamig | HY-P990903 is an CD3E/CD33-targeting [H-γ1 _ L-κ-scFv heavy -κ]-dimer type bispecific antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YMS-5A. CAS No. 2577961-36-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990903. | |
| Avitriptan | Avitriptan is an antimigraine drug of the triptan family which was never marketed. It acts as a 5-HT1B and 5-HT1D receptor agonist. Synonyms: 1-[3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methyl-methanesulfonamide. Grade: > 95%. CAS No. 151140-96-4. Molecular formula: C22H30N6O3S. Mole weight: 458.59. | |
| Avizafone dihydrobromide | Avizafone (Pro-diazepam) dihydrobromide, a pro-drug of Diazepam, is an anticonvulsant agent. Avizafone dihydrobromide can be used as an antidote of nerve agent poisoning. In vivo, Avizafone dihydrobromide is rapidly hydrolyzed by aminopeptidase to produce lysine and diazepam. Avizafone dihydrobromide has research areas including neurological disease, such as epilepsy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pro-diazepam dihydrobromide. CAS No. 60067-15-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W702001. | |
| Avizakimab | Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BOS161721. CAS No. 2229685-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99451. | |
| AVJ16 | AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with a good affinity of Kd of 1.4μM. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2775241-92-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144873. | |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Synonyms: CC-292; CC292; CC 292; AVL292; AVL 292; spebrutinib. Grade: 98%. CAS No. 1202757-89-8. Molecular formula: C22H22FN5O3. Mole weight: 423.44. | |
| AVL-292 benzenesulfonate | AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed. Synonyms: Spebrutinib besylate; CC-292 besylate; AVL-292 benzenesulfonate; CC 292 besylate; AVL 292 benzenesulfonate; CC292 besylate; AVL292 benzenesulfonate. Grade: >98%. CAS No. 1360053-81-1. Molecular formula: C28H28FN5O6S. Mole weight: 581.62. | |
| AVN-101 hydrochloride | AVN-101 hydrochloride is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist (Ki of 153 pM), with slightly lesser potency toward 5-HT6, 5-HT2A, and 5HT-2C receptors (Ki values of 2.04 nM, 1.56 ?nM, and 1.17? nM, respectively). AVN-101 hydrochloride also exhibits a rather high affinity toward histamine H1 (Ki of 0.58 nM) and adrenergic α2A, α2B, and α2C (Ki= 0.41-3.6 nM) receptors. AVN-101 hydrochloride can be studied in such diseases as general anxiety disorders, depression, schizophrenia, Alzheimers disease, and multiple sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1061354-48-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117046A. | |
| AVN-101 hydrochloride | AVN-101 is an antagonist of the serotonin (5-HT) receptor subtypes 5-HT7, 5-HT2C, 5-HT2A, and 5-HT6 (Kis = 0.153, 1.17, 1.56, and 2.04 nM, respectively). It is also an antagonist of α2A-, α2B-, α2C-, α1B-, α1A-, and α1D-adrenergic receptors (Kis = 0.41, 1.77, 3.55, 9.4, 18.9, and 30.2 nM, respectively), as well as histamine H1 and H2 (Kis = 0.58 and 89 nM, respectively), but not H3, receptors. It is a multi-target drug candidate for the treatment of CNS disorders. Synonyms: 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride; AVN-101 HCl; 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-, hydrochloride (1:1); 2,8-dimethyl-5-(2-phenylethyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride; 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-1H-pyrido[4,3-b]indole, monohydrochloride. Grade: ≥95%. CAS No. 1061354-48-0. Molecular formula: C21H25ClN2. Mole weight: 340.90. | |
| AVN-211 | This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-211 shows good anxiolytic efficacy, low toxicity ,no side effects in vivo, an appropriate pharmacokinetic profile and good stability. AVN-211 significantly delayed or partially halted the progressive decline in memory function associated with AD and this efficacy makes it an interesting drug candidate for the treatment of neurodegenerative and psychiatric disorders. In Jul 2015, Avineuro Pharmaceuticals completed a phase II trial in Schizophrenia in USA and planed a trial for Alzheimer's disease in USA. In Aug 2015, Phase-II development was ongoing for Schizophrenia in USA. Uses: Alzheimer's disease;schizophrenia. Synonyms: AVN-211; AVN 211; AVN211; CD-008-0173. 5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine,CD-008-0173. Grade: 98%. CAS No. 1173103-84-8. Molecular formula: C15H15N3O2S2. Mole weight: 333.42. | |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Synonyms: AVN-492; AVN 492; AVN492. 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine. CAS No. 1220646-23-0. Molecular formula: C17H21N5O2S. Mole weight: 359.45. | |
| AVN-944 | AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine triphosphate (GTP), a purine molecule required for DNA and RNA synthesis. AVN944 appears to have a selective effect on cancer cells in that deprivation of GTP in normal cells results in a temporary slowing of cell growth only. Synonyms: code name: AVN 944; AVN944; VX-944; VX 944; VX944. Grade: 0.98. CAS No. 297730-17-7. Molecular formula: C25H27N5O5. Mole weight: 477.51. | |
| AVN-944 | AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-944. CAS No. 297730-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13560. | |
| Avobenzone | Avobenzone, also known as butyl methoxydibenzoylmethane, is an organic sunscreen agent of the dibenzoylmethane class. It is the most widely used UVA I filter (340-400 nm) in broad-spectrum sunscreen formulations and exists in an enol-keto tautomeric equilibrium that is key to its UV absorption mechanism. Applications: Used in broad-spectrum sunscreen formulations for uva i photoprotection. avobenzone is the most widely used organic uva filter covering the 340-400 nm range, providing essential protection against deep skin penetration and photoaging caused by long-wave ultraviolet radiation. Category: Active pharmaceutical ingredients. Synonyms: 4-tert-butyl-4'-methoxy-dibenzoylmethane;4-T-BUTYL-4'-METHOXY-DIBENZOYLMETHANE;1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione. CAS No. 70356-09-1. Product ID: API70356091. Molecular formula: C20H22O3. Mole weight: 310.4. EINECS: 274-581-6. InChIKey: XNEFYCZVKIDDMS-UHFFFAOYSA-N. Appearance: White to off-white solid. |  |
| Avobenzone | Avobenzone. Group: Biochemicals. Alternative Names: 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione; Butyl methoxydibenzoyl methane . Grades: Highly Purified. CAS No. 70356-09-1. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C20H22O3. US Biological Life Sciences. | Worldwide |
| Avobenzone (Standard) | Avobenzone (Standard) is the analytical standard of Avobenzone. This product is intended for research and analytical applications. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 70356-09-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0316R. | |
| Avocado Extract | Avocado (Persea gratissima) fruit extract, 20% in water-glycerin, rich in vitamins B2, D, A, E, K, and potassium; anti-irritant and soothing. CAS No. 84695-98-7. Product ID: CI-SC-0795. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Avocado Extract | Avocado Extract. Applications: Used for health care products, dietary supplements, herb medicine and cosmetic industry. Group: Others. Synonyms: Avocado Extract; Persea americana L. Purity: 30% Total Phytosterol by UV. Appearance: Yellow Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Persea americana L. Avocado Extract; Persea americana L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-122. |  |
| Avocado Oil | Avocado oil, 100% virgin, refined and expeller pressed. Easily absorbed, deeply moisturizing. Alternative Names: Persea gratissima oil. CAS No. 8024-32-6. Purity: 98%. Product ID: CI-SC-0520. Alfa Chemistry - ISO 9001:32057 Certified. | |
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