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| Product | Description | |
|---|---|---|
| AZ31 | AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC50 of <1.2 nM for ATM enzyme, and an IC50 of 46 nM for ATM in cell. AZ31 shows excellent selectivity over ATR (>500-fold) and excellent PIKK-family selectivity and pan-kinase selectivity. AZ31 is a potent radiosensitizer in vitro, it can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2088113-98-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-112198. |  |
| AZ'3137 | AZ3137 is an orally active PROTAC-type androgen receptor (AR) degrader with a DC50 value of 22 nM. AZ3137 can degrade L702H mutant AR (DC50 of 92 nM). AZ'3137 can inhibit cell proliferation of LNCaP, with a GI50 value of 74 nM. AZ'3137 can inhibit AR signaling and tumor growth in prostate cancer mice (Pink: AR Ligand (HY-172954); Blue: CRBN ligand (HY-172955); Black: linker (HY-W262798); E3 Ligand+Linker: HY-172956)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2960179-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162702. | |
| AZ3146 | AZ3146 is a reasonably potent Mps1 and TTK inhibitor, with IC50 of 35 nM for Mps1Cat. Uses: Scientific research. Category: Signaling pathways. CAS No. 1124329-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14710. | |
| AZ 3146 | AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit. Synonyms: AZ3146; AZ 3146; AZ-3146. Grade: >98%. CAS No. 1124329-14-1. Molecular formula: C24H32N6O3. Mole weight: 452.55. |  |
| AZ32 | AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 2288709-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112305. | |
| AZ32 | AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with IC50 of <6.2 nM for ATM enzyme and IC50 of 0.31 μM for ATM in cell. AZ32 is tolerated in C57Bl6 and Nude mice dosed orally at 200mg/kg which was efficacious in orthotopic mouse models. AZ32 is the first ATMi with oral bioavailability shown to radiosensitize glioma and improve survival in orthotopic mouse models. It also shows adequate selectivity over ATR and also has high cell permeability. Synonyms: AZ-32; AZ 32; N-methyl-4-(6-phenylimidazo[1,2-a]pyrazin-3-yl)benzamide. Grade: ≥98%. CAS No. 2288709-96-4. Molecular formula: C20H16N4O. Mole weight: 328.37. | |
| AZ3246 | AZ3246 is an orally active and selective inhibitor of HPK1 with an IC50 of < 3 nM. AZ3246 induces IL-2 secretion in T cells with an EC50 of 90 nM. AZ3246 is a low-clearance antitumor compound that can be used for the study of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2893978-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173006. | |
| Az-33 | Az-33 is a lactate dehydrogenase A (LDHA) inhibitor, which is a key enzyme in anaerobic glycolysis process and is deregulated in human malignancies. Uses: Az-33 is a lactate dehydrogenase a (ldha) inhibitor. Synonyms: Az 33; Az33; 2-(4-(4-((3-((2-Methylbenzo[d]thiazol-6-yl)amino)-3-oxopropyl)amino)-4-oxobutyl)benzyl)malonic acid. Grade: ≥98%. CAS No. 1370290-34-8. Molecular formula: C25H27N3O6S. Mole weight: 497.56. | |
| AZ3451 | AZ3451 is a potent protease-activated receptor-2 (PAR2) antagonist with IC50 of 23 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2100284-59-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112558. | |
| AZ 3451 | AZ3451 is a potent and selective allosteric antagonist of protease-activated receptor 2 (PAR2) with IC50 of 23 nM. AZ3451 was found to bind to a remote allosteric site outside the helical bundle that is different from the site previously found on PAR1. The interaction of AZ3451 with PAR2 is predominately hydrophobic in nature. AZ3451 binds to a remote allosteric site outside the helical bundle, which prevents structural rearrangements required for receptor activation and signaling. Synonyms: 2-(6-Bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]-1H-benzimidazole-5-carboxamide; AZ-3451; AZ3451. Grade: ≥98%. CAS No. 2100284-59-9. Molecular formula: C30H27BrN4O3. Mole weight: 571.46. | |
| AZ3976 | AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with IC50 of 26 μM in an enzymatic chromogenic assay. AZ3976 inhibited PAI-1 by enhancing the latency transition of active PAI-1. Synonyms: AZ 3976; AZ-3976. Grade: >98%. CAS No. 1418747-15-5. Molecular formula: C15H19N5O3. Mole weight: 317.34. | |
| AZ505 | AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 μM) with potential anticancer activity. Synonyms: AZ 505; AZ-505; N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide. Grade: 98%. CAS No. 1035227-43-0. Molecular formula: C29H38Cl2N4O4. Mole weight: 577.54. | |
| AZ505 | AZ505 is a potent and selective SMYD2 inhibitor with an IC50 of 0.12 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1035227-43-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15226. | |
| AZ505 ditrifluoroacetate | AZ505 ditrifluoroacetate is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 μM) with potential anticancer activity. Synonyms: AZ505 ditrifluoroacetate; AZ 505 ditrifluoroacetate; AZ-505 ditrifluoroacetate. Grade: >98%. CAS No. 1035227-44-1. Molecular formula: C33H40Cl2F6N4O8. Mole weight: 805.59. | |
| AZ506 | AZ506 is a potent SMYD2 inhibitor (IC50 = 17 nM) that inhibits SMYD2 methyltransferase activity in cells, resulting in a decrease in the SMYD2-mediated methylation signal. Synonyms: 3-Pyridinecarboxamide, 5-[2-[4-[2-(1H-indol-3-yl)ethyl]-1-piperazinyl]phenyl]-N-[3-(1-pyrrolidinyl)propyl]-; 5-(2-{4-[2-(1H-Indol-3-yl)ethyl]-1-piperazinyl}phenyl)-N-[3-(1-pyrrolidinyl)propyl]nicotinamide. Grade: ≥95%. CAS No. 2043321-54-4. Molecular formula: C33H40N6O. Mole weight: 536.71. | |
| AZ506 | AZ506 is a potent SMYD2 inhibitor with an IC50 of 17 nM. AZ506 inhibits SMYD2 methyltransferase activity in cells, leading to a decrease in the SMYD2-mediated methylation signal[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2043321-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134828. | |
| AZ5104 | AZ5104 is a potent EGFR inhibitor and a derivative of AZD 9291. AZ5104 exhibits reduced selectivity against wild-type EGFR but five-fold potentcy compared to AZD 9291. Synonyms: AZ-5104; AZ 5104; N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide. CAS No. 1421373-98-9. Molecular formula: C27H31N7O2. Mole weight: 485.592. | |
| AZ-5104 | AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421373-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0793. | |
| AZ5576 | AZ5576 is a potent and highly selective CDK9 inhibitor (IC50: <5 nM). AZ5576 inhibits the phosphorylation of RNA polymerase II at Ser2, thereby inhibiting transcriptional elongation. AZ5576 can be used for hematological Malignancy research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2751721-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143584. | |
| AZ 5704 | AZ 5704 is a potent and selective ATM kinase inhibitor with IC50 of 0.6 nM in an enzyme inhibition assay. It exhibits 600-fold selectivity for ATM over other kinases. AZ 5704 is also orally bioavailable. Synonyms: 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide; AZ-5704; AZ5704. Grade: ≥98%. CAS No. 1941214-06-7. Molecular formula: C23H23FN6O2. Mole weight: 434.47. | |
| AZ6102 | AZ6102 is a moderate oral bioavailable dual inhibitor of TNKS1/2 with excellent selectivity against other PARP family enzymes including PARP-1, PARP-2 and PARP-6. It also inhibits Wnt signaling in DLD-1 cells. IC50: TNKS2= 1 nM; TNKS1= 3 nM; Wnt signaling. Synonyms: 2-[4-[6-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl]phenyl]-7-methyl-1H-pyrrolo[2,3-d]pyrimidin-4-oneAZ6102; AZ-6102; AZ 6102.AZ 6102|rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidi. CAS No. 1645286-75-4. Molecular formula: C25H28N6O. Mole weight: 428.53. | |
| AZ6102 | AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50s of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50s of 2.0 μM, 0.5 μM, and >3 μM, for PARP1, PARP2, and PARP6, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1645286-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12975. | |
| AZ617 | AZ617 is a human-specific, TLR4-dependent agonist that activates NFκB. Synonyms: AZ-617; AZ 617. Grade: 98% by HPLC. CAS No. 2247439-36-5. Molecular formula: C40H38N4O4. Mole weight: 638.8. | |
| AZ 628 | AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 878739-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11004. | |
| AZ 628 | AZ628 is a potent, ATP-competitive inhibitor of Raf kinases (IC50 values are 29, 34 and 105 nM for c-Raf1, B-RafV600E and wild-type B-Raf, respectively). It displays selectivity for Raf kinases over a panel of 150 other kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. Synonyms: AZ628; AZ-628; AZ 628. Grade: >98%. CAS No. 878739-06-1. Molecular formula: C27H25N5O2. Mole weight: 451.52. | |
| AZ'6421 | AZ'6421 acts as Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor alpha. AZ'6421 has a potent anti-tumour effect to inhibit the uncontrolled cellular proliferation which arises from malignant disease. AZ'6421 can be used for the research of cancer such as breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361115-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-135312. | |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Synonyms: AZ-7371; AZ 7371; TBA-7371; DprE1-IN-1. Grade: 98%. CAS No. 1494675-86-3. Molecular formula: C18H21N5O3. Mole weight: 355.40. | |
| AZ7550 | AZ7550, an active metabolite of AZD9291, inhibits IGF1R activity with an IC50 of 1.6 μM in a cell-free assay. Synonyms: Osimertinib metabolite M3; 2-Propenamide, N-(4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl)amino)-2-(methyl(2-(methylamino)ethyl)amino)phenyl)-; N-(4-Methoxy-5-((4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl)amino)-2-(methyl(2-(methylamino)ethyl)amino)phenyl)-2-propenamide; N-(4-Methoxy-5-{[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}phenyl)acrylamide. Grade: ≥95%. CAS No. 1421373-99-0. Molecular formula: C27H31N7O2. Mole weight: 485.58. | |
| AZ7550 | AZ7550 is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421373-99-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0794. | |
| AZ7550 hydrochloride | AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits IGF1R activity with an IC50 of 1.6 μM in a cell-free assay. Synonyms: N-(4-Methoxy-5-{[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}phenyl)acrylamide hydrochloride (1:1); 2-Propenamide, N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 2309762-40-9. Molecular formula: C27H32ClN7O2. Mole weight: 522.04. | |
| AZ7550 Mesylate | AZ7550 Mesylate, an active metabolite of AZD9291, inhibits the activity of IGF1R with an IC50 of 1.6 μM. Synonyms: AZ7550 trimesylate salt; N-(4-Methoxy-5-{[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}phenyl)acrylamide methanesulfonate (1:3); 2-Propenamide, N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-, methanesulfonate (1:3). Grade: ≥98%. CAS No. 2319837-99-3. Molecular formula: C30H43N7O11S3. Mole weight: 773.90. | |
| AZ82 | AZ82 is a kinesin-14 family protein that is important for assembling bipolar spindles in cancer cells containing supernumerary centrosomes. AZ82 is a selective kinesin-like protein HSET inhibitor with Ki of 43 nM and KIFC1 inhibitor with IC50 of 300 nM. It shows microtubule-noncompetitive manner but does not inhibit basal KIFC1 activity at a concentration of 100 μM. In Vitro, AZ82 is shown to specifically induce multipolar spindles in BT-549 cells, but not in cancer cells with normal centrosome number, such as HeLa. Synonyms: AZ-82; AZ 82. Grade: ≥98%. CAS No. 1449578-65-7. Molecular formula: C28H31F3N4O3S. Mole weight: 560.6. | |
| AZ82 | AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449578-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12241. | |
| AZ876 | AZ876 is a novel high-affinity LXR agonist with Ki values of 0.007 μM and 0.011 μM for human LXRα and LXRβ respectively, it was previously shown to inhibit progression of atherosclerosis in mice without incurring the aforementioned adverse effects. Whether AZ876 exerts additional protection in the heart remains to be explored. LXR activation with AZ876 attenuated this increase, and significantly reduced TAC-induced increases in heart weight, myocardial fibrosis, and cardiac dysfunction without affecting blood pressure. AZ876 was also 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human. Synonyms: AZ 876; AZ-876; AZ12260493; AZ 12260493; AZ-12260493. Grade: ≥98%. CAS No. 898800-26-5. Molecular formula: C24H29N3O3S. Mole weight: 439.57. | |
| AZ8838 | AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2100285-41-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123617. | |
| AZ9482 | AZ9482 is a triple PARP1/2/6 inhibitor, with IC50 values of 1 nM, 1 nM and 640 nM for PARP1, PARP2 and PARP6, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1825345-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-119653. | |
| AZ'9567 | AZ'9567 is an orally active MAT2a inhibitor with a pIC50 of 9.1. AZ'9567 binds to MAT2a allosterically, reduces the synthesis of SAM, decreases SDMA levels, and exerts antiproliferative effects on MTAP-knockout cells. AZ'9567 depletes SAM, causes methionine accumulation in plasma and tissues, triggers adaptive disorders in one-carbon metabolism, transsulfuration metabolism and lipid metabolism, and induces oxidative stress, hepatic steatosis and lipid homeostasis imbalance. AZ'9567 can be used in studies related to MTAP-deficient/deleted cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056570-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162353. | |
| AZ960 | AZ960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 905586-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10411. | |
| AZ-960 | AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM. Synonyms: (S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; 3-Pyridinecarbonitrile, 5-fluoro-2-(((1S)-1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)-; 5-Fluoro-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]nicotinonitrile. Grade: >98%. CAS No. 905586-69-8. Molecular formula: C18H16F2N6. Mole weight: 354.36. | |
| AZA | ~4-fold increase in efficiency with OSKM and promotes full reprogramming. Uses: Reprogramming. Synonyms: 3'-Azido-2',3'-dideoxyadenosine; 66323-44-2; 3'-Azido-ddA; 3'-AzddAdo; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azidooxolan-2-yl]methanol; 3'-N3-ddA; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azido-tetrahydrofuran-2-yl]methanol; HG1022; 3'-Azido-2'-deoxyadenosine; CHEMBL590121; SCHEMBL18640424; DTXSID10216534; XDRZJDXXQHFAAE-RRKCRQDMSA-N; MFCD01630963; AKOS037644233; ((2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidotetrahydrofuran-2-yl)methanol; AS-49374; CS-0199753; A835421; 9-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-.beta.-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-beta-D-erythro-pentofuranosyl)adenine; [(2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidooxolan-2-yl]methanol; 9H-purin-6-amine, 9-(3-azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-. Grade: ≥ 97%. CAS No. 66323-44-2. Molecular formula: C10H12N8O2. Mole weight: 276.26. | |
| AZA1 | AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rac1/Cdc42-IN-1. CAS No. 1071098-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-136383. | |
| Azacetidine Monoacetate | Azacetidine Monoacetate is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: ((2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl acetate; 1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one. CAS No. 1174733-90-4. Molecular formula: C10H14N4O6. Mole weight: 286.24. | |
| Azacitidine | Azacitidine is a pyrimidine nucleoside analogue of cytidine, classified as a nucleoside metabolic inhibitor with antineoplastic activity. It was initially FDA-approved in 2004 for adult myelodysplastic syndromes and subsequently approved for pediatric juvenile myelomonocytic leukemia in 2022. Applications: Azacitidine is indicated for adult patients with myelodysplastic syndrome subtypes including refractory anemia, refractory anemia with excess blasts, and chronic myelomonocytic leukemia. it is also indicated for pediatric patients aged one month and older with newly diagnosed juvenile myelomonocytic leukemia. Category: Anti-tumor apis. Synonyms: 5-azacytidine, Ladakamycin. CAS No. 320-67-2. Product ID: API0232320. Mole weight: 244.2. EINECS: 206-280-2. InChIKey: NMUSYJAQQFHJEW-KVTDHHQDSA-N. Appearance: White crystalline powder. |  |
| Azacitidine Impurity 1 | Azacitidine Impurity 1. Uses: For analytical and research use. CAS No. 645-92-1. Molecular formula: C3H5N5O. Mole weight: 127.11. Catalog: APB645921. |  |
| Azacitidine Impurity 1 | Azacitidine Impurity 1. Uses: For analytical and research use. Alternative Names: 4-amino-1-((2R,3R,4R,5R)-3-(((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one. Molecular formula: C13H20N4O9. Mole weight: 376.32. Catalog: APB03066. | |
| Azacitidine Impurity 10 | Azacitidine Impurity 10. Uses: For analytical and research use. Alternative Names: N-((Z)-N'-(((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)carbamoyl)carbamimidoyl)formamide. Molecular formula: C8H14N4O6. Mole weight: 262.22. Catalog: APB03061. | |
| Azacitidine Impurity 11 | Azacitidine Impurity 11. Uses: For analytical and research use. Alternative Names: Azacitidine Impurity 11. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB03063. | |
| Azacitidine Impurity 12 | Azacitidine Impurity 12. Uses: For analytical and research use. Alternative Names: N-(Aminoiminomethyl)-N'-ß-D-ribofuranosylurea. CAS No. 2508-80-7. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB2508807. | |
| Azacitidine Impurity 2 | Azacitidine Impurity 2. Uses: For analytical and research use. CAS No. 16352-06-0. Molecular formula: C4H6N4O. Mole weight: 126.12. Catalog: APB16352060. | |
| Azacitidine Impurity 25 | Azacitidine Impurity 25. Uses: For analytical and research use. CAS No. 686299-20-7. Molecular formula: C8H14N4O6. Mole weight: 262.22. Catalog: APB686299207. | |
| Azacitidine Impurity 26 | Azacitidine Impurity 26. Uses: For analytical and research use. Molecular formula: C25H32N4O15. Mole weight: 628.54. Catalog: APB06378. | |
| Azacitidine Impurity 27 | Azacitidine Impurity 27. Uses: For analytical and research use. Alternative Names: Azacitidine Impurity 27. Molecular formula: C7H14N4O5. Mole weight: 234.10. Catalog: APB03049. | |
| Azacitidine Impurity 28 | Azacitidine Impurity 28. Uses: For analytical and research use. Molecular formula: C13H20N4O8. Mole weight: 360.32. Catalog: APB06379. | |
| Azacitidine Impurity 28 | Azacitidine Impurity 28. Uses: For analytical and research use. Alternative Names: Azacitidine Impurity 28. CAS No. 2775292-14-1. Molecular formula: C7H14N4O5. Mole weight: 234.10. Catalog: APB2775292141. | |
| Azacitidine Impurity 29 | Azacitidine Impurity 29. Uses: For analytical and research use. Alternative Names: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)amino)-1,3,5-triazin-2(1H)-one. Molecular formula: C13H20N4O9. Mole weight: 376.12. Catalog: APB03047. | |
| Azacitidine Impurity 3 | Azacitidine Impurity 3. Uses: For analytical and research use. Alternative Names: ((2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl acetate. CAS No. 1174733-90-4. Molecular formula: C10H14N4O6. Mole weight: 286.24. Catalog: APB1174733904. | |
| Azacitidine Impurity 30 | Azacitidine Impurity 30. Uses: For analytical and research use. Alternative Names: (2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl acetate. Molecular formula: C10H14N4O6. Mole weight: 286.09. Catalog: APB03046. | |
| Azacitidine Impurity 31 | Azacitidine Impurity 31. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl dibenzoate. Molecular formula: C22H20N4O7. Mole weight: 452.42. Catalog: APB03045. | |
| Azacitidine Impurity 32 | Azacitidine Impurity 32. Uses: For analytical and research use. Alternative Names: N-(9-acetyl-9H-purin-6-yl)benzamide. Molecular formula: C14H11N5O2. Mole weight: 281.27. Catalog: APB03044. | |
| Azacitidine Impurity 35 | Azacitidine Impurity 35. Uses: For analytical and research use. CAS No. 41546-19-4. Molecular formula: C5H10O5. Mole weight: 150.13. Catalog: APB41546194. | |
| Azacitidine Impurity 36 | Azacitidine Impurity 36. Uses: For analytical and research use. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB06380. | |
| Azacitidine Impurity 37 | Azacitidine Impurity 37. Uses: For analytical and research use. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB06381. | |
| Azacitidine Impurity 39 | Azacitidine Impurity 39. Uses: For analytical and research use. Molecular formula: C8H14N4O6. Mole weight: 262.22. Catalog: APB06383. | |
| Azacitidine Impurity 4 | Azacitidine Impurity 4. Uses: For analytical and research use. Alternative Names: 4,6-diamino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one. CAS No. 105331-00-8. Molecular formula: C8H13N5O5. Mole weight: 259.22. Catalog: APB105331008. | |
| Azacitidine Impurity 40 | Azacitidine Impurity 40. Uses: For analytical and research use. CAS No. 2306050-23-5. Molecular formula: C13H20N4O9. Mole weight: 376.32. Catalog: APB2306050235. | |
| Azacitidine Impurity 41 | Azacitidine Impurity 41. Uses: For analytical and research use. Molecular formula: C13H20N4O9. Mole weight: 376.32. Catalog: APB06384. | |
| Azacitidine Impurity 42 | Azacitidine Impurity 42. Uses: For analytical and research use. Molecular formula: C15H16N4O6. Mole weight: 348.32. Catalog: APB06386. | |
| Azacitidine Impurity 43 | Azacitidine Impurity 43. Uses: For analytical and research use. Molecular formula: C22H20N4O7. Mole weight: 452.42. Catalog: APB06385. | |
| Azacitidine Impurity 44 | Azacitidine Impurity 44. Uses: For analytical and research use. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB06387. | |
| Azacitidine Impurity 45 | Azacitidine Impurity 45. Uses: For analytical and research use. Molecular formula: C13H20N4O8. Mole weight: 360.32. Catalog: APB06390. | |
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