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| Product | Description | |
|---|---|---|
| Azaribine | It is an antineoplastic agent. Uses: Dermatologic agents. Synonyms: AZARIBINE; Triazure; 2169-64-4; 6-Azauridine 2',3',5'-triacetate; 6-Azaribine; CB 304; Azaribinum; Azaribina; Triacetyl-6-azauridine; 6-Azauridine triacetate; CB-304; NSC-67239; Azauridine triacetate; NSC 67239; K1U80DO9EB; MLS000069488; DTXSID1022635; TA-Azur; 2-beta-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione 2',3',5'-triacetate; 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-beta-D-rib. Grade: ≥95%. CAS No. 2169-64-4. Molecular formula: C17H20O6. Mole weight: 323.35. |  |
| Azaserine | Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI-337; O-Diazoacetyl-L-serine; P-165. CAS No. 115-02-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0919. |  |
| Azaserine | It is produced by the strain of Streptomyces fragilis 04926. Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. Uses: Antibiotics, antifungal; antibiotics, antineoplastic; antimetabolites; antimetabolites, antineoplastic; carcinogens; immunosuppressive agents. Synonyms: diazoacetate (ester) L-Serine; diazoacetylserine; serine diazoacetate. Grade: 98%. CAS No. 115-02-6. Molecular formula: C5H7N3O4. Mole weight: 173.13. | |
| Azasetron-13C,D3 Hydrochloride | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-13C,d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| Azasetron-d3 hydrochloride | Azasetron-d3 hydrochloride. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride. CAS No. 1216505-58-6. Purity: 96%. Product ID: ACM1216505586. Molecular formula: C17H18D3Cl2N3O3. Mole weight: 389.29. IUPAC Name: N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-3-oxo-4-(trideuteriomethyl)-1,4-benzoxazine-8-carboxamide;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Azasetron-[d3] Hydrochloride | Azasetron-[d3] Hydrochloride is the labelled analogue of Azasetron Hydrochloride, which is a 5-HT3 receptor antagonist and used as an antiemetic. Synonyms: Azasetron-d3 Hydrochloride; N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; Serotone-d3; Nazasetron-d3; Y-25130-d3 hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide-d3 hydrochloride. Grade: 98%; ≥99% atom D. CAS No. 1216505-58-6. Molecular formula: C17H18D3Cl2N3O3. Mole weight: 389.29. | |
| Azasetron-d3, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Azasetron hydrochloride | Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy. Uses: Antiemetics. Synonyms: Azasetron hydrochloride; Y 25130; Y-25130; Y25130. Y-25130 HCl. Grade: >98%. CAS No. 123040-16-4. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron hydrochloride | Azasetron hydrochloride. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide hydrochloride. Grades: Highly Purified. CAS No. 123040-69-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H21Cl2N3O3. US Biological Life Sciences. | Worldwide |
| Azasetron hydrochloride | Azasetron hydrochloride. Alternative Names: Y-25130;Y-25130 HYDROCHLORIDE;N-1-AZABICYCLO[2.2.2]-OCT-3-YL-6-CHLORO-3,4-DIHYDRO-4-METHYL-3-OXO-2H-1,4-BENZOXAZINE-8-CARBOXAMIDE, HYDROCHLORIDE;n-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2h-1,4-benzoxazine-8-carboxamide hydrochlor. CAS No. 141922-90-9. Product ID: ACM141922909. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Azasetron, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Azasetron Impurity 2 | Azasetron Impurity 2. Uses: For analytical and research use. Alternative Names: 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylic acid. CAS No. 123040-79-9. Molecular formula: C10H8ClNO4. Mole weight: 241.63. Catalog: APB123040799. |  |
| Azatadine | Azatadine is a new antihistamine acts as histamine for histamine H1- receptor inhibitor ( IC50 = 6.5 nM and 10 nM, respectively). Uses: Antihistaminic. Synonyms: 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta-[1,2-b]pyridine; 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0³,?]pentadeca-1(15),3(8),4,6,11,13-hexaene. Grade: ≥98%. CAS No. 3964-81-6. Molecular formula: C20H22N2. Mole weight: 290.40. | |
| Azatadine dimaleate | Azatadine dimaleate. Group: Biochemicals. Alternative Names: 6, 11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine; Azatadine Dimaleate. Grades: Highly Purified. CAS No. 3964-81-6,3978-86-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H22N2. US Biological Life Sciences. | Worldwide |
| Azatadine Dimaleate | Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively. Uses: Histamine h1 antagonists. Synonyms: SCH10649; SCH 10649; SCH-10649. Grade: >98%. CAS No. 3978-86-7. Molecular formula: C20H22N2.2C4H4O4. Mole weight: 522.55. | |
| Azatadine Dimaleate. | Antihistaminic. Group: Biochemicals. Alternative Names: 6, 11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine (2Z)-2-Butenedioate; 5- (4'-N-methyl piperidyl ide ne )-4-azo-10: 11-di hydrodibenzocyclohe ptene Dimaleate; Atoramin; Azatadine Maleate; Bonamid; Idulian; Optimine; Sch 10649; Trinalin; Zadine. Grades: Highly Purified. CAS No. 3978-86-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azathioprine | Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Uses: Antimetabolites. Synonyms: azathioprine; 446-86-6; Imuran; Azothioprine; Azathioprin; Azamun; Azanin; Azatioprin; Azasan; Ccucol; Imurek; Imurel; Muran; Azathiopurine; Rorasul; Azathioprinum; BW 57-322; NSC-39084; BW-57-322; Azatioprina; 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine; NCI-C03474; NSC 39084; Methylnitroimidazolylmercaptopurine; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine; Azathioprinum [INN-Latin]; Azatioprina [INN-Spanish]; CCRIS 62; Imuran (TN); 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; HSDB 7084; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine; Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-. Grade: >98%. CAS No. 446-86-6. Molecular formula: C9H7N7O2S. Mole weight: 277.26. | |
| Azathioprine | Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BW 57-322. CAS No. 446-86-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-B0256. | |
| Azathioprine | Azathioprine. Group: Biochemicals. Grades: Purified. CAS No. 446-86-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azathioprine-13C4 | Labeled Azathioprine. An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD). Group: Biochemicals. Alternative Names: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4; BW-57-322-13C4; NSC-39084-13C4; Azanin-13C4; Imuran-13C4; Imurek-13C4; Imurel-13C4; Zytrim-13C4. Grades: Highly Purified. CAS No. 1346600-71-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Azathioprine-[13C4] | Azathioprine-[13C4] is the labelled analogue of Azathioprine. Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Synonyms: Azathioprine-13C4; 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4; BW-57-322-13C4; NSC-39084-13C4; Azanin-13C4; Imuran-13C4; Imurek-13C4; Imurel-13C4; Zytrim-13C4. Grade: ≥96%; ≥98% atom 13C. CAS No. 1346600-71-2. Molecular formula: C5[13C]4H7N7O2S. Mole weight: 281.23. | |
| Azathioprine (6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, BW-57-322, NSC-39084,. Azanin, Imuran, Imurek, Imurel, Zytrim) | An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD). Group: Biochemicals. Alternative Names: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, BW-57-322, NSC-39084,Azanin, Imuran, Imurek, Imurel, Zytrim. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azathioprine EP Impurity A | Azathioprine EP Impurity A. Uses: For analytical and research use. CAS No. 4531-54-8. Molecular formula: C4H6N4O2. Mole weight: 142.12. Catalog: APB4531548. | |
| Azathioprine EP Impurity A | Azathioprine EP Impurity A. Uses: For analytical and research use. Alternative Names: 1-methyl-4-nitro-1H-imidazol-5-amine. Molecular formula: C4H6N4O2. Mole weight: 142.12. Catalog: APB02970. | |
| Azathioprine EP Impurity B | Azathioprine EP Impurity B. Uses: For analytical and research use. Alternative Names: 7H-purine-6-thiol. Molecular formula: C5H4N4S. Mole weight: 152.18. Catalog: APB02969. | |
| Azathioprine EP Impurity B | Azathioprine EP Impurity B. Uses: For analytical and research use. CAS No. 157930-13-7. Molecular formula: C5H4N4S. Mole weight: 152.17. Catalog: APB157930137. | |
| Azathioprine EP Impurity C | Azathioprine EP Impurity C. Uses: For analytical and research use. Alternative Names: 5-chloro-1-methyl-4-nitro-1H-imidazole. Molecular formula: C4H4ClN3O2. Mole weight: 161.55. Catalog: APB02967. | |
| Azathioprine EP Impurity C | Azathioprine EP Impurity C. Uses: For analytical and research use. CAS No. 4897-25-0. Molecular formula: C4H4ClN3O2. Mole weight: 161.54. Catalog: APB4897250. | |
| Azathioprine EP Impurity D | Azathioprine EP Impurity D. Uses: For analytical and research use. CAS No. 6339-54-4. Molecular formula: C4H5N3O2S. Mole weight: 159.16. Catalog: APB6339544. | |
| Azathioprine EP Impurity D | Azathioprine EP Impurity D is a metabolite of Azathioprine. Synonyms: 1-Methyl-4-nitro-5-thioimidazole; 1-Methyl-4-nitro-1H-imidazole-5-thiol; 5-Mercapto-1-methyl-4-nitroimidazole. Grade: > 95%. CAS No. 6339-54-4. Molecular formula: C4H5N3O2S. Mole weight: 159.17. | |
| Azathioprine EP Impurity D | Azathioprine EP Impurity D. Uses: For analytical and research use. Alternative Names: 1-methyl-4-nitro-1H-imidazole-5-thiol. Molecular formula: C4H5N3O2S. Mole weight: 159.17. Catalog: APB02968. | |
| Azathioprine EP Impurity E | Azathioprine EP Impurity E. Uses: For analytical and research use. CAS No. 73703-74-9. Molecular formula: C4H5N3O3. Mole weight: 143.1. Catalog: APB73703749. | |
| Azathioprine EP Impurity E Sodium Salt | Azathioprine EP Impurity E Sodium Salt is a degradation product of Azathioprine. Synonyms: 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt; 1-Methyl-4-nitro-1H-imidazol-5-ol Sodium Salt. Grade: > 95%. CAS No. 35681-68-6. Molecular formula: C4H4N3O3Na. Mole weight: 165.08. | |
| Azathioprine EP Impurity F | Azathioprine EP Impurity F. Uses: For analytical and research use. CAS No. 68-94-0. Molecular formula: C5H4N4O. Mole weight: 136.11. Catalog: APB68940. | |
| Azathioprine EP Impurity F | Azathioprine EP Impurity F. Uses: For analytical and research use. Alternative Names: 1H-purin-6(7H)-one. Molecular formula: C5H4N4O. Mole weight: 136.11. Catalog: APB02965. | |
| Azathioprine EP Impurity G | Azathioprine EP Impurity G. Uses: For analytical and research use. Alternative Names: 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-6,7-dihydro-1H-purin-2-amine. Molecular formula: C9H10N8O2S. Mole weight: 294.29. Catalog: APB02964. | |
| Azathioprine EP Impurity G | Azathioprine EP Impurity G. Uses: For analytical and research use. CAS No. 5581-52-2. Molecular formula: C9H8N8O2S. Mole weight: 292.28. Catalog: APB5581522. | |
| Azathioprine Impurity 10 | Azathioprine Impurity 10. Uses: For analytical and research use. CAS No. 15965-30-7. Molecular formula: C3H2Cl2N2. Mole weight: 136.96. Catalog: APB15965307. | |
| Azathioprine Impurity 15 | Azathioprine Impurity 15. Uses: For analytical and research use. CAS No. 304441-05-2. Molecular formula: C11H9N7O3S. Mole weight: 319.3. Catalog: APB304441052. | |
| Azathioprine Impurity 16 | Azathioprine Impurity 16. Uses: For analytical and research use. CAS No. 152529-79-8. Molecular formula: C14H14N4O5S. Mole weight: 350.35. Catalog: APB152529798. | |
| Azathioprine Impurity 17 | Azathioprine Impurity 17. Uses: For analytical and research use. CAS No. 5437-25-2. Molecular formula: C5H4N4S2. Mole weight: 184.24. Catalog: APB5437252. | |
| Azathioprine Impurity 19 | Azathioprine Impurity 19. Uses: For analytical and research use. Molecular formula: C5H3N5OS. Mole weight: 181.17. Catalog: APB06508. | |
| Azathioprine Impurity 20 | Azathioprine Impurity 20. Uses: For analytical and research use. Molecular formula: C10H6N8S. Mole weight: 270.27. Catalog: APB06507. | |
| Azathioprine Impurity 3 | Azathioprine Impurity 3. Uses: For analytical and research use. CAS No. 5167-18-0. Molecular formula: C6H6N4O. Mole weight: 150.14. Catalog: APB5167180. | |
| Azathioprine Impurity 4 | Azathioprine Impurity 4. Uses: For analytical and research use. CAS No. 30467-02-8. Molecular formula: C6H6N4O. Mole weight: 150.14. Catalog: APB30467028. | |
| Azathioprine Impurity 5 | Azathioprine Impurity 5. Uses: For analytical and research use. CAS No. 253453-91-7. Molecular formula: C4H5ClN2. Mole weight: 116.55. Catalog: APB253453917. | |
| Azathioprine Impurity 6 | Azathioprine Impurity 6. Uses: For analytical and research use. CAS No. 4897-21-6. Molecular formula: C4H5ClN2. Mole weight: 116.55. Catalog: APB4897216. | |
| Azathioprine Impurity 7 | Azathioprine Impurity 7. Uses: For analytical and research use. Alternative Names: 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-7H-purine. Molecular formula: C9H7N7O2S. Mole weight: 277.26. Catalog: APB02966. | |
| Azathioprine Impurity 7 | Azathioprine Impurity 7. Uses: For analytical and research use. CAS No. 1192-53-6. Molecular formula: C4H4Cl2N2. Mole weight: 150.99. Catalog: APB1192536. | |
| Azathioprine Impurity 8 | Azathioprine Impurity 8. Uses: For analytical and research use. CAS No. 873-25-6. Molecular formula: C4H3Cl3N2. Mole weight: 185.43. Catalog: APB873256. | |
| Azathioprine Impurity 9 | Azathioprine Impurity 9. Uses: For analytical and research use. CAS No. 872-49-1. Molecular formula: C4H5ClN2. Mole weight: 116.55. Catalog: APB872491. | |
| Azathioprine Impurity C | Azathioprine Impurity C is an impurity of 6-Mercaptopurine, which is an immunosuppressive drug used to treat leukemia. Synonyms: 6-Mercaptopurine Disulfide; 6,6'-Dithiodi-9H-purine; 6,6'-Dithiodi-purine; Bis(6-purinyl) disulfide; 1,2-Di(9H-purin-6-yl)disulfane; NSC 166569; NSC 77640. Grade: > 95%. CAS No. 49808-20-0. Molecular formula: C10H6N8S2. Mole weight: 302.34. | |
| Azathioprine Related Compound A | Azathioprine Related Compound A. Uses: For analytical and research use. CAS No. 4531-54-8. Mole weight: 142.12. Catalog: AP4531548. | |
| Azathioprine Related Compound G | Azathioprine Related Compound G. Uses: For analytical and research use. CAS No. 5581-52-2. Mole weight: 292.28. EC Number: 226-977-5. Catalog: AP5581522. | |
| Azathioprine Sodium | Azathioprine Sodium is an immunosuppressive antimetabolite that functions as a prodrug of 6-mercaptopurine (6-MP). Administered in its sodium salt form to improve solubility, it is widely used in both organ transplantation and the treatment of autoimmune diseases. As an imidazoline derivative of 6-mercaptopurine, it interferes with purine nucleotide synthesis and lymphocyte proliferation. Applications: Azathioprine sodium is used as an immunosuppressive agent in organ transplantation (renal, hepatic, cardiac) for the prevention of allograft rejection, and in the management of autoimmune conditions including systemic lupus erythematosus (sle), rheumatoid arthritis, crohn's disease, and ulcerative colitis. Category: Active pharmaceutical ingredients. Synonyms: 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-, sodium salt. CAS No. 55774-33-9. Product ID: API55774339. Molecular formula: C9H6N7NaO2S. Mole weight: 299.25. InChIKey: WISNYKIQFMKSDQ-UHFFFAOYSA-N. Appearance: Solid. |  |
| Azauracil olein amine salt | Azauracil olein amine salt. CAS No. 99400-75-6. Product ID: ACM99400756. Molecular formula: C18H37N.C3H3N3O2. Mole weight: 380.573. Alfa Chemistry - ISO 9001:32057 Certified. | |
| AzBTS | AzBTS. Uses: For analytical and research use. Alternative Names: 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic Acid Ammonium Salt). CAS No. 30931-67-0. Molecular formula: C18H24N6O6S4. Mole weight: 548.67. Purity: >98.0%(T)(HPLC). Catalog: APB30931670. | |
| AZD0022 | AZD0022 is a selective and orally active KRASG12D inhibitor. AZD0022 inhibits KRAS pathway suppression in the GP2D xenograft model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2958627-18-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173637. | |
| AZD0095 | AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib (HY-10205)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750001-23-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148517. | |
| AZD0156 | AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1821428-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100016. | |
| AZD0156 | AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage checkpoint activation, and disrupts DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells. Uses: Protein kinase inhibitors. Synonyms: 8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one; AZD0156; AZD-0156; AZD 0156. CAS No. 1821428-35-6. Molecular formula: C26H31N5O3. Mole weight: 461.56. | |
| AZD-0284 | AZD-0284 is a reverse agonist of the nuclear receptor (RORγ). AZD-0284 has the potential for the treatment of plaque psoriasis vulgaris and respiratory tract disorders. Synonyms: AZD0284; AZD 0284. CAS No. 2101291-07-8. Molecular formula: C21H18F6N2O5S. Mole weight: 524.43. | |
| AZD 0328 | AZD 0328 is a potent α7 NNR/5HT3 receptor agonist. AZD0328 led to a significant increase in cortical dopamine release in awake rodents and improved both conditioned response learning and memory retention in an object recognition task. Synonyms: (3R)-spiro[1-azabicyclo[2.2.2]octane-3,2'-3H-furo[2,3-b]pyridine]; AZD 0328; AZD-0328; AZD0328; UNII-2B218X5QIY; spiro(1-azabicyclo(2.2.2)octane-3,2'(3H)-furo(2,3-b)pyridine). Grade: >98%. CAS No. 220099-91-2. Molecular formula: C13H16N2O. Mole weight: 216.28. | |
| AZD0364 | AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. Synonyms: AZD-0364; AZD 0364; tizaterkib. Grade: ≥98%. CAS No. 2097416-76-5. Molecular formula: C24H24F2N8O2. Mole weight: 494.50. | |
| AZD0424 | AZD0424 is an orally bioavailable small molecule tyrosine kinase inhibitor. It targets both Abl and Src kinases with potential antineoplastic activity. It selectively inhibits both Src and Abl kinase activity and may result in the inhibition of tumor growth in susceptible tumor cells. Uses: Azd0424 has the inhibition of tumor growth in tumor cells. Synonyms: AZD 0424; AZD-0424; 1-(4-(2-((4-((6-chloro-[1,3]dioxolo[4,5-b]pyridin-7-yl)amino)-5-isopropoxyquinazolin-7-yl)oxy)ethyl)piperazin-1-yl)ethan-1-one; 7-(2-(4-Acetylpiperazin-1-yl)ethoxy)-4-(5-chloro-2,3-methylenedioxypyridin-4-ylamino)-5-isopropoxyquinazoline. Grade: 98%. CAS No. 692054-06-1. Molecular formula: C25H29ClN6O5. Mole weight: 528.99. | |
| AZD-0837 | AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. Uses: Potassium channel antagonist. Synonyms: AZD0837; AZD-0837; AZD 0837; Atecegatran metoxil; Atecegatran fexenetil.1-((2R)-(3-chloro-5- (difluoromethoxy)phenyl)hydroxyacetyl)-N-((4-(imino(methoxyamino)methyl)phenyl)methyl)-, (2S)-2-Azetidinecarboxamide; (S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide. Grade: ≥95%. CAS No. 433937-93-0. Molecular formula: C22H23ClF2N4O5. Mole weight: 496.89. | |
| AZD1080 | AZD1080 is a brain-permeable GSK3 inhibitor with Ki values of 6.9 nM and 31 nM for GSK3α and GSK3β, respectively. Study showed that AZD1080 inhibited tau phosphorylation in cells. It also suppresses ovarian cancer cell proliferation, invasion, migration, and lamellipodia formation, and induces G1 arrest. Synonyms: AZD-1080; 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile. Grade: >98%. CAS No. 612487-72-6. Molecular formula: C19H18N4O2. Mole weight: 334.37. | |
| AZD1080 | AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3α and GSK3β with pKi (IC50) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 612487-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13862. | |
| AZD1080 | AZD1080 Inhibitor. Uses: Scientific use. Product Category: T1741. CAS No. 612487-72-6. |  |
| AZD1152-HQPA | Barasertib is a potent and highly selective inhibitor of AURKB with IC50 of 0.37 nM, acting via preventing the transfer of the phosphate group from the ATP molecule to AURKB substrates. The present study demonstrated for the first time, that AURKB inhibition interferes with early regeneration of SGs. Barasertib has been demonstrated that it is 3,700-fold greater selectivity than Aurora A. Synonyms: INH 34; AZD1152-HQPA; AZD2811. Grade: ≥98%. CAS No. 722544-51-6. Molecular formula: C26H30FN7O3. Mole weight: 507.56. | |
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