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| Product | Description | |
|---|---|---|
| Arzoxifene hydrochloride | Arzoxifene (LY353381) hydrocloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY353381 hydrochloride; SERM III hydrochloride. CAS No. 182133-27-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13556A. |  |
| AS-041164 | The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism. AS-041164 is a highly potent and selective PI3Kγ inhibitor that inhibits PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ with IC50 values of 240 nM, 1.45 μM, 70 nM and 1.70 μM, respectively. It also blocks RANTES-induced neutrophil migration and displays anti-inflammatory activity in various in vivo rodent models. Synonyms: 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione. Grade: ≥98%. CAS No. 6318-41-8. Molecular formula: C11H7NO4S. Mole weight: 249.2. |  |
| AS101 | AS101 is a synthetic non-toxic tellurium derivative, structurally similar to cisplatin, with immuno-modulating, antiviral, and hair growth-promoting activities. This agent is also a potent inducer of IL-1 and IL-6. Accordingly, ammonium trichlorotellurate may protect against chemotherapy-induced alopecia. Synonyms: AS-101; IVX-Q-101; PRX-0001; PRX-0002; PRX-001; WAX-120337; IVXQ-101; AS101; IVXQ101; PRX0001; PRX0002; PRX001; WAX120337; AS 101; IVX Q 101; PRX 0001; PRX 0002; PRX 001; WAX 120337; IVXQ 101; US brand name: Ossirene; IVX-Q-101. Ammonium trichloro(dioxoethylene-O,O') tellurate. CAS No. 106566-58-9. Molecular formula: C2H4Cl3O2Te.H4N. Mole weight: 312.049. | |
| AS 101 | AS 101. Group: Biochemicals. Grades: Purified. CAS No. 106566-58-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| AS 101 | AS 101. Uses: Designed for use in research and industrial production. Appearance: White crystalline solid. CAS No. 106566-58-9. Molecular formula: C2H4Cl3O2Te·NH4. Mole weight: 312.05. Purity: 0.95. Product ID: ACM106566589. Alfa Chemistry ISO 9001:2015 Certified. Categories: AS-101. |  |
| AS 1269574 | AS 1269574. Group: Biochemicals. Grades: Purified. CAS No. 330981-72-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS 1269574 | GPR119 has been found to be a GPR119 agonist and could stimulate the activity of proglucagon gene promoter. Synonyms: AS1269574; AS-1269574; AS 1269574; 2-[[2-(4-Bromophenyl)-6-methyl-4-pyrimidinyl]amino]ethanol. Grade: ≥98% by HPLC. CAS No. 330981-72-1. Molecular formula: C13H14BrN3O. Mole weight: 308.17. | |
| AS-136A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| AS 1411 sodium | AS1411 sodium is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. It has anti-tumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGRO-100 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147081A. | |
| AS1517499 | AS1517499 is a potent and brain-permeable STAT6 phosphorylation inhibitor with an IC50 of 21 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 919486-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100614. | |
| AS1517499 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AS 1517499 | AS 1517499 is a potent and selective STAT6 inhibitor (IC50 = 21 nM). Synonyms: AS-1517499; AS1517499; AS 1517499. 4-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide. Grade: 99%. CAS No. 919486-40-1. Molecular formula: C20H20ClN5O2. Mole weight: 397.86. | |
| AS-1669058 | AS-1669058 is a G-protein-coupled receptor 119 (GPR119) agonist originated by Astellas Pharma. No recent reports of development were identified for preclinical development in Type-2-diabetes-mellitus in Japan. Uses: Type 2 diabetes mellitus. Synonyms: 3-(2-((2-(4-bromo-2,5-difluorophenyl)-6-methylpyrimidin-4-yl)amino)ethyl)pyridine 1-oxide; AS 1535907; AS 1669058; AS 1907417; GPR119 agonists - Astellas Pharma; 1395553-32-8(OXLATE). Grade: 98%. CAS No. 1395553-31-7. Molecular formula: C18H15BrF2N4O. Mole weight: 421.24. | |
| AS-1669058 oxalate | AS-1669058 is a G-protein-coupled receptor 119 (GPR119) agonist originated by Astellas Pharma. No recent reports of development were identified for preclinical development in Type-2-diabetes-mellitus in Japan. Uses: Type 2 diabetes mellitus. Synonyms: AS-1669058 oxalate; AS 1669058 oxalate; AS1669058 oxalate; 3-(2-((2-(4-bromo-2,5-difluorophenyl)-6-methylpyrimidin-4-yl)amino)ethyl)pyridine 1-oxide oxalate. Grade: 98%. CAS No. 1395553-32-8. Molecular formula: C18H15BrF2N4O.C2H2O4. Mole weight: 511.28. | |
| AS1810722 | AS1810722 shows potent STAT6 inhibition and a good CYP3A4 inhibition profile. Synonyms: AS-1810722. Grade: 98%. CAS No. 909561-15-5. Molecular formula: C25H25F2N7O. Mole weight: 477.51. | |
| AS1810722 | AS1810722 is an orally active and potent STAT6 inhibitor with an IC50 of 1.9 nM. AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909561-15-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134772. | |
| AS-183 | AS-183 is an enzyme inhibitor produced by Scedosporium sp. SPC-15549. Synonyms: 3(2H)-Furanone, 2-hydroxy-2,4-dimethyl-5-(1,3,5,7-tetramethylnonyl)-. Grade: >98%. CAS No. 147317-12-2. Molecular formula: C19H34O3. Mole weight: 310.47. | |
| AS1842856 | AS1842856, a specific Foxo1 inhibitor (IC50=30 nM), potently suppresses autophagy[1]. AS1842856 reduces Foxo1 activity and, to a lesser extent, inhibits Foxo1 protein expression by simply binding to Foxo1[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 836620-48-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-100596. | |
| AS 1842856 | AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Synonyms: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Grade: 98%. CAS No. 836620-48-5. Molecular formula: C18H22FN3O3. Mole weight: 347.38. | |
| AS-186c | AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Synonyms: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82. | |
| AS-186d | AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Synonyms: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86. | |
| AS 1892802 | AS 1892802 has been found to be an ATP-competitive ROCK inhibitor and could show analgesic activities at some extent. Synonyms: AS 1892802; AS1892802; AS-1892802; N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea. Grade: ≥99% by HPLC. CAS No. 928320-12-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| AS 1892802 | AS 1892802. Group: Biochemicals. Grades: Purified. CAS No. 928320-12-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS 19 | AS 19 has been found to be a potent SR-7 agonist and could probably enhance memory consolidation. Synonyms: AS 19; AS-19; AS19; (2S)-(+)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin. Grade: ≥98% by HPLC. CAS No. 1000578-26-6. Molecular formula: C18H25N3. Mole weight: 283.41. | |
| AS 19 | Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced. Group: Biochemicals. Alternative Names: (2S) - (+) -5- (1, 3, 5-Trimethylpyrazol-4-yl) -2- (dimethylamino) tetralin. Grades: Highly Purified. CAS No. 1000578-26-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 283.41. US Biological Life Sciences. | Worldwide |
| AS1940477 | AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent concentrations of AS1940477 that inhibited cytokine production also inhibited TNFα- and IL-1 β-induced production of IL-6, PGE(2), and MMP-3 in human synovial stromal cells. AS1940477 was also found to potently inhibit TNF production in whole blood (IC(50)=12 nM) and effectively inhibited TNFα production induced by systemically administered LPS in rats at less than 0.1mg/kg (ED(50)=0.053 mg/kg) with an anti-inflammatory effect lasting for 20h after oral administration. Overall, this study demonstrated that AS1940477 is a novel and potent p38 MAPK inhibitor and may be useful as a promising anti-inflammatory agent for treating inflammatory disorders. Synonyms: AS1940477; AS-1940477; AS 1940477. CAS No. 928344-12-1. Molecular formula: C24H22FN5O2. Mole weight: 431.47. | |
| AS1949490 | AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 μM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1203680-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18686. | |
| AS1949490 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AS 1949490 | AS 1949490. Group: Biochemicals. Grades: Purified. CAS No. 1203680-76-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS 1949490 | AS1949490 has been found to be a selective SHIP2 phosphatase inhibitor and show antidiabetic activities. Synonyms: AS1949490; AS-1949490; AS 1949490; 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide. Grade: ≥99% by HPLC. CAS No. 1203680-76-5. Molecular formula: C20H18ClNO2S. Mole weight: 371.88. | |
| AS 2034178 | AS 2034178 has been found to be a FFA1/GPR40 agonist and could probably be used against diabetes. Synonyms: AS 2034178; AS2034178; AS-2034178; 2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoic acid. Grade: ≥98% by HPLC. CAS No. 1030846-42-4. Molecular formula: C27H29FN2O3. Mole weight: 448.53. | |
| AS 2034178 | AS 2034178. Group: Biochemicals. Grades: Purified. CAS No. 1030846-42-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS2444697 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AS-2444697 HCl | AS-2444697 is a pootent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50 = 21 nM) with 30-fold selectivity for IRAK4 over IRAK1. AS2444697 significantly reduced or showed a decreasing trend in expression and levels of these inflammatory parameters. Synonyms: N-(3-carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide hydrochloride; AS-2444697; AS 2444697; AS2444697; AS-2444697 HCl; AS-2444697 hydrochloride. CAS No. 1287665-60-4. Molecular formula: C19H21ClN6O4. Mole weight: 432.86. | |
| AS 252424 | AS 252424. Group: Biochemicals. Grades: Purified. CAS No. 900515-16-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AS-252424 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| AS-252424 | AS-252424 is a novel, potent PI3Kγ inhibitor (IC50 of 30 nM) with a 30-fold selectivity for PI3Kγ than PI3Kα, and low inhibitory activity towards PI3Kδ/β. Synonyms: AS252424; AS 252424; AS-252424. Grade: >98%. CAS No. 900515-16-4. Molecular formula: C14H8FNO4S. Mole weight: 305.28. | |
| AS 252424 bispotassium salt | AS 252424 bispotassium salt is the potassium salt form of AS 252424, which is a potent and selective PI3K p110γ inhibitor. Synonyms: AS 252424 bispotassium salt; AS252424 bispotassium salt; AS-252424 bispotassium salt; dipotassium (5Z)-5-[[5-(4-fluoro-2-oxidophenyl)furan-2-yl]methylidene]-4-oxo-1,3-thiazol-2-olate. Grade: 99%. Molecular formula: C14H6FNO4S.K2. Mole weight: 381.46. | |
| AS2717638 | AS2717638 is a potent, selective, orally active and brain-penetrant lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC50 of 38 nM for hLPA5. It significantly improves allodynia induced by PGE2, PGF2α and AMPA. Synonyms: 1(2H)-Isoquinolinone, 6,7-dimethoxy-2-(5-methyl-1,2-benzisoxazol-3-yl)-4-(1-piperidinylcarbonyl)-; 6,7-Dimethoxy-2-(5-methyl-1,2-benzoxazol-3-yl)-4-(piperidin-1-ylcarbonyl)isoquinolin-1(2H)-one; 6,7-Dimethoxy-2-(5-methyl-1,2-benzoxazol-3-yl)-4-(1-piperidinylcarbonyl)-1(2H)-isoquinolinone. Grade: ≥95%. CAS No. 2148339-28-8. Molecular formula: C25H25N3O5. Mole weight: 447.48. | |
| AS2717638 | AS2717638 is a highly selective, brain-penetrant and orally active lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 38 nM. AS2717638 is highly selective and shows no significant antagonistic activity against other LPA receptors (LPA1, LPA2, and LPA3). AS2717638 can be used in the research of pain and neuroinflammation-related diseases[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2148339-28-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114379. | |
| AS2863619 | AS2863619 is an orally active cyclin-dependent kinase CDK8/19 inhibitor with IC50 of 0.61 nM and 4.277 nM, respectively. In vitro, AS2863619 is a potent Foxp3 inducer in Tconv cells. Synonyms: 4-[1-(2-methyl-1H-benzimidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine dihydrochloride; 4-(1-(2-Methyl-1H-benzo[d]imidazol-6-yl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride. CAS No. 2241300-51-4. Molecular formula: C16H14Cl2N8O. Mole weight: 405.24. | |
| AS2863619 | AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241300-51-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126675A. | |
| AS2863619 free base | STAT5 activation enhanced by AS2863619 free base inhibits CDK8/19, which consequently activates the Foxp3 gene. Synonyms: AS2863619 (free base). Grade: 98%. CAS No. 2241300-50-3. Molecular formula: C16H12N8O. Mole weight: 332.32. | |
| AS-35 | AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation. Uses: As-35 is used as an antiallergic drug. Synonyms: AS 35; AS35; AS-35; 3-(1H-Tetrazol-5-yl)-9-[[[2-propyl-3-hydroxy-4-(methylcarbonyl)phenyl]oxy]methyl]-4H-pyrido[1,2-a]pyrimidin-4-one; AS35; 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-; 9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one. Grade: >98%. CAS No. 108427-72-1. Molecular formula: C21H20N6O4. Mole weight: 420.42. | |
| AS601245 | AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 345987-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11010. | |
| AS601245 | AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. Synonyms: AS601245; AS-601245; AS 601245. Grade: >98%. CAS No. 345987-15-7. Molecular formula: C20H16N6S. Mole weight: 372.45. | |
| AS601245 | Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| AS-601811 | AS-601811 is a 5-α reductase (type 1) inhibitor developed for the treatment of acne. Synonyms: 4,8-dimethyl-1,2,5,6-tetrahydrobenzo[f]quinolizin-3-one; AS-601811; AS 601811; AS601811; UNII-LIV8A6AE5F. Grade: >98%. CAS No. 194979-95-8. Molecular formula: C15H17NO. Mole weight: 227.307. | |
| AS 602801 | AS 602801 is a novel, orally active inhibitor of JNK. It blocked T-lymphocyte proliferation and induced apoptosis. Synonyms: AS602801; AS-602801; AS 602801; PGL5001; PGL-5001; PGL 5001; Bentamapimod. Grade: >98%. CAS No. 848344-36-5. Molecular formula: C25H23N5O2S. Mole weight: 457.55. | |
| AS 604850 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| AS-604850 | AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα. Synonyms: AS604850; AS 604850; AS-604850. PI3K gamma inhibitor; PI 3-Kgamma Inhibitor II; (5E)-5-[(2,2-Difluoro-1,3-benzodioxol-5-YL)methylene]-1,3-thiazolidine-2,4-dione. Grade: 98%. CAS No. 648449-76-7. Molecular formula: C11H5F2NO4S. Mole weight: 285.211. | |
| AS605240 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AS 605240 | AS 605240. Group: Biochemicals. Grades: Purified. CAS No. 648450-29-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS-605240 | AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis. Synonyms: AS 605240; AS605240; AS-605240. Grade: 0.98. CAS No. 648450-29-7. Molecular formula: C12H7N3O2S. Mole weight: 257.267. | |
| AS-605240 potassium salt | Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer. AS-605240 inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively. AS-605240 also inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells with an IC50 value of 90 nM. AS-605240 potassium salt is the potassium salt form of AS-605240, which increase the water-solubility. Synonyms: AS-605240. Grade: ≥98%. Molecular formula: C12H6N3O2S·K. Mole weight: 295.4. | |
| AS-703026 | AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Group: Biochemicals. Alternative Names: N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide. Grades: Highly Purified. CAS No. 1236699-92-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| AS8351 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AS8351 | AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC51355. CAS No. 796-42-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100744. | |
| AS 8351 | AS 8351 has been found to show the activity in inducing reprogramming of human fetal lung fibroblasts into functional cardiomyocytes. Synonyms: AS-8351; AS-8351; AS-8351; 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone. Grade: ≥98% by HPLC. CAS No. 796-42-9. Molecular formula: C17H13N3O2. Mole weight: 291.30. | |
| AS-85 | AS-85 is a potent inhibitor of ASH1L histone methyltransferase with an IC50 of 0.6 μM. AS-85 has anti-leukemic activity and strongly binds to the ASH1L SET domain, with a Kd of 0.78 μM. Synonyms: 3-Azetidinecarboxamide, N-[[3-[3-(aminothioxomethyl)phenyl]-1-[1-[(trifluoromethyl)sulfonyl]-4-piperidinyl]-1H-indol-6-yl]methyl]-. CAS No. 2323623-80-7. Molecular formula: C26H28F3N5O3S2. Mole weight: 579.66. | |
| AS-85 | AS-85 is a potent ASH1L histone methyltransferase inhibitor ( IC 50 =0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the K d value of 0.78?μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2323623-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141430. | |
| AS-99 | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50 =?0.79?μM, Kd =?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. Molecular formula: C27H31ClF3N5O3S2. Mole weight: 630.14. | |
| AS-99 free base | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50=?0.79?μM, Kd=?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. CAS No. 2323623-93-2. Molecular formula: C27H30F3N5O3S2. Mole weight: 593.68. | |
| AS-99 TFA | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50=?0.79?μM, Kd=?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. Synonyms: AS-99 (TFA); AS-99 TFA; HY-141429A; MS-31187; CS-0227299. Grade: ≥98%. Molecular formula: C29H31F6N5O5S2. Mole weight: 707.71. | |
| ASAFETIDA TINCTURE | ASAFETIDA TINCTURE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASAFETIDA TINCTURE;ASAFOETIDA OIL;FEMA 2108;Asafetida;asafoetida;Asafoetidagum;asant;asefetida. Product Category: Heterocyclic Organic Compound. CAS No. 9000-4-8. Product ID: ACM9000048. Alfa Chemistry ISO 9001:2015 Certified. | |
| Asarinin | Asarinin. Group: Biochemicals. CAS No. 133-04-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Asarinin | Asarinin. Group: Biochemicals. Alternative Names: (-)-Episesamin. Grades: Plant Grade. CAS No. 133-04-0. Pack Sizes: 20mg. Molecular Formula: C20H18O6, Molecular Weight: 354.353. US Biological Life Sciences. | Worldwide |
| Asarone | Asarone. Group: Biochemicals. Grades: Plant Grade. CAS No. 2883-98-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asarylaldehyde | Asarylaldehyde. Group: Biochemicals. Grades: Plant Grade. CAS No. 4460-86-0, 14374-62-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asatone | Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 38451-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6826. | |
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