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| Product | Description | |
|---|---|---|
| Avocado Oil | Avocado Oil. CAS No. 8024-32-6. VIGON Item # 507697. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers, Cosmetics. |  America & Internationally |
| Avocado Powder | Avocado powder takes avocado as raw material, adopts spray drying technology, low temperature physical grinding technology, instant grinding, to obtain edible high quality avocado powder. Product ID: CDF4-0226. Category: Flavour. Product Keywords: Flavor Enhancers; Avocado Powder; CDF4-0226; Flavour;. Grade: Food Grade. Color: White powder. Physical State: powder. Storage: Room Temperature. Applications: It is widely used in processing various avocado flavored foods and added to various nutritional foods. |  |
| Avoralstat | Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCX4161. CAS No. 918407-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16735. |  |
| Avoralstat | Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: BCX-4161; BCX 4161; BCX4161. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54. |  |
| Avosentan | Avosentan, also known as SPP301, R-639, and RO 67-0565, is a potent and selective endothelin receptor(ETA receptor) antagonist. Synonyms: N-[6-methoxy-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-yl]-5-methylpyridine-2-sulfonamide; Avosentan; 290815-26-8; UNII-L94KSX715K; SPP301; SPP301; SPP301; RO 67-0565; RO-67-0565; RO67-0565; R-639; Avosentan. Grade: 95%. CAS No. 290815-26-8. Molecular formula: C23H21N5O5S. Mole weight: 479.51. | |
| Avosentan | Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma. Group: Biochemicals. Alternative Names: N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 67-0565; SPP 301. Grades: Highly Purified. CAS No. 290815-26-8. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Avotaciclib | Avotaciclib (BEY1107) is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BEY1107. CAS No. 1983983-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137432. | |
| Avotaciclib | Avotaciclib is a potent and orally active CDK1 inhibitor that can be studied in locally advanced or metastatic pancreatic cancer. Synonyms: BEY1107; 3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)-. CAS No. 1983983-41-0. Molecular formula: C13H11N7O. Mole weight: 281.27. | |
| Avotaciclib trihydrochloride | Avotaciclib trihydrochloride is a potent and orally active CDK1 inhibitor that can be studied in locally advanced or metastatic pancreatic cancer. Synonyms: BEY1107 trihydrochloride; 3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)-, hydrochloride (1:3). CAS No. 1983984-01-5. Molecular formula: C13H11N7O.3HCl. Mole weight: 390.66. | |
| Avotaciclib trihydrochloride | Avotaciclib (BEY1107) trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib trihydrochloride can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib trihydrochloride can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BEY1107 trihydrochloride. CAS No. 1983984-01-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-137432A. | |
| Avrainvillamide | Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Synonyms: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grade: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52. | |
| Avrainvillamide | Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Avrainvillamide; CJ-17,665. CAS No. 269741-97-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 250 μg; 250 μg. Product ID: HY-N10264. | |
| Avridine | A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Group: Biochemicals. Alternative Names: 2, 2'- [ [3- (Dioctadecylamino) propyl] imino] bisethanol; CP 20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane; N, N-Dioctadecyl-N', N'-bis (2-hydroxyethyl) propanediamine. Grades: Highly Purified. CAS No. 35607-20-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avridine | Avridine is a potent synthetic non-immunogenic adjuvant that used to induce arthritis in Lewis (LEW) and DA rats. Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Synonyms: CP 20961; CP20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane. Grade: ≥98%. CAS No. 35607-20-6. Molecular formula: C43H90N2O2. Mole weight: 667.19. | |
| Avutometinib | Avutometinib (Ro 5126766) is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 5126766; CH5126766. CAS No. 946128-88-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18652. | |
| AVX 13616 | AVX 13616 shows the potent in vivo antibacterial activity of Avexa's lead antibacterial candidate, particularly against drug-resistant Staphylococcus pathogens. It was as active as mupirocin in a nasal decolonization model but required only a single application. It showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. Synonyms: AVX-13616; AVX 13616; AVX13616. Grade: >98%. CAS No. 900814-48-4. Molecular formula: C50H73Cl2N7O7. Mole weight: 955.06. | |
| Avycaz | Avycaz is a fixed-dose combination medication composed of ceftazidime, a cephalosporin antibiotic, and avibactam, a β-lactamase inhibitor. Synonyms: ceftazidime & avibactam; ceftazidime + avibactam; Avibactam / Ceftazidime. CAS No. 1393723-27-7. Molecular formula: C29H33N9O13S3. Mole weight: 811.8. | |
| Awamycin | Awamycin is produced by the strain of Streptomyces sp. No. 80-217. It has anti-gram-positive bacteria and antitumor activity. Synonyms: Antibiotic Tan 528A; Protostreptovaricin I, 10,25-didemethyl-21-hydroxy-10-(methoxycarbonyl)-19-O-methyl-25-(methylthio)-; Protostreptovaricin-31-oic acid, 25-demethyl-21-hydroxy-19-O-methyl-2S-(methylthio)-, methyl ester. Molecular formula: C38H49NO12S. Mole weight: 743.86. | |
| AWD 12-281 | AWD 12-281 is a strong selective phosphodiesterase 4 (PDE4) inhibitor which has potent effects in models of lung inflammation using inhalative administration. Synonyms: N-(3,5-dichloropyridin-4-yl)-2-[1-[(4-fluorophenyl)methyl]-5-hydroxyindol-3-yl]-2-oxoacetamide; AWD 12-281; AWD12-281; AWD-12-281; UNII-550671J24D; GSK 842470; GSK 842470; GSK-842470. Grade: >98%. CAS No. 257892-33-4. Molecular formula: C22H14Cl2FN3O3. Mole weight: 458.27. | |
| AWD 131-138 | AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy. Synonyms: AWD 131-138; AWD-131-138; AWD131-138; AWD 131138; Imepitoin; 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one. CAS No. 188116-07-6. Molecular formula: C13H14ClN3O2. Mole weight: 279.724. | |
| AX-024 | AX-024 is a first-in-class and orally available TCR-Nck interaction inhibitor that selectively inhibits TCR-triggered T cell activation with an IC50 of ~1 nM. It regulates cell signaling by targeting SH3 domains. It strongly inhibits the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. Synonyms: 1-[[4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]pyrrolidine; Pyrrolidine, 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-. Grade: ≥98%. CAS No. 1370544-73-2. Molecular formula: C21H22FNO2. Mole weight: 339.40. | |
| AX-024 | AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. Uses: Scientific research. Category: Signaling pathways. CAS No. 1370544-73-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107390. | |
| AX-024 hydrochloride | AX-024 hydrochloride is an inhibitor of T cell receptor (TCR) that selectively inhibits the TCR-Nck interaction. By modulating TCR signaling, AX-024 prevents the development of psoriasis and asthma and, furthermore, exerts a long-lasting therapeutic effect in a model of autoimmune encephalomyelitis. Synonyms: 1-[[4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]pyrrolidine hydrochloride; Pyrrolidine, 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-, hydrochloride (1:1). Grade: 99%. CAS No. 1704801-24-0. Molecular formula: C21H22FNO2.HCl. Mole weight: 375.86. | |
| AX-024 hydrochloride | AX-024 hydrochloride is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 hydrochloride modulates cell signaling by targeting SH3 domains. AX-024 hydrochloride has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. Uses: Scientific research. Category: Signaling pathways. CAS No. 1704801-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107390A. | |
| AX 048 | Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate (AX 048) is a PLA2 (Phospholipase A2) and PGE2 (Prostaglandin E2) inhibitor. PLA2 is known as calcium-dependent cytosolic PLA2 (cPLA2), which selectively releases arachidonic acid from membrane phospholipids. It plays a central role in initiating the synthesis of prostaglandins and leukotrienes. This compound also contains a specific affinity for group IVA cPLA2 which moderates antihyperalgesia effects. Synonyms: AX-048; AX 048; Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester; UNII-8782Z45DLV; 8782Z45DLV; Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester; ethyl 4-(2-oxohexadecanoylamino)butanoate; ethyl 4-(2-oxohexadecanamido)butanoate; CHEMBL574723; SCHEMBL4781039; DTXSID60236282; AKOS040755666; ethyl 4-[(2-oxohexadecanoyl)amino] butanoate; Q27269809; 4- [(1, 2- dioxohexadecyl)amino]- butanoic acid, ethyl ester. Grade: ≥98%. CAS No. 873079-69-7. Molecular formula: C22H41NO4. Mole weight: 383.6. | |
| AX-15836 | AX-15836 is a highly potent and selective ERK5 inhibitor (IC50 = 8 nM) with >1,000-fold selectivity for ERK5 over a panel of over 200 kinases. Synonyms: 2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one; AKOS030210962; ZINC669678933; AX15836; AX 15836; AX-15836. CAS No. 2035509-96-5. Molecular formula: C32H40N8O5S. Mole weight: 648.78. | |
| AX-15836 | AX-15836 is a potent and selective ERK5 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2035509-96-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101846. | |
| AX20017 | AX20017 is a highly selective PknG inhibitor. It acts by blocking the proliferation of M. tuberculosis. AX20017 is shown to completely inactivate PknG-mediated blockage of lysosomal transfer and degradation of M. bovis BCG in macrophages at concentrations (10μM or higher) that does not otherwise affect the growth of BCG outside its infected host. Synonyms: AX 20017; AX-20017; PknG Inhibitor; 2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide. Grade: ≥98% (HPLC). CAS No. 329221-38-7. Molecular formula: C13H16N2O2S. Mole weight: 264.35. | |
| Axatilimab | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SNDX-6352. CAS No. 2155851-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99452. | |
| AXC-715 | AXC-715 is a dual agonist of TLR7/TLR8. Synonyms: 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-; 4-Amino-2-butyl-1H-imidazo[4,5-c]quinoline-1-butanamine; 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine; AXC 715; AXC715. Grade: ≥95%. CAS No. 313350-31-1. Molecular formula: C18H25N5. Mole weight: 311.43. | |
| AXC-715 hydrochloride | AXC-715 hydrochloride is a dual agonist of TLR7/TLR8. (Extracted from patent WO2020168017 A1). Synonyms: 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride; 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-, hydrochloride (1:1). Grade: ≥90%. CAS No. 2490497-93-1. Molecular formula: C18H26ClN5. Mole weight: 347.89. | |
| AXC-715 hydrochloride | AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist. AXC-715 can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T785 hydrochloride. CAS No. 2490497-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-138139A. | |
| AXC-715 trihydrochloride | AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist. AXC-715 trihydrochloride can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T785 trihydrochloride. CAS No. 2479276-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138139B. | |
| AXC-715 trihydrochloride | AXC-715 trihydrochloride is a dual agonist of TLR7/TLR8. (Extracted from patent WO2020168017 A1). Synonyms: 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine Trihydrochloride; 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-, hydrochloride (1:3). Grade: 95%. CAS No. 2479276-17-8. Molecular formula: C18H28Cl3N5. Mole weight: 420.81. | |
| Axenomycin B | Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities. Molecular formula: C29H38O10. Mole weight: 546.60. | |
| Axinysone A | Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Synonyms: (-)-Axinysone A. Grade: 97.5%. CAS No. 1114491-57-4. Molecular formula: C15H22O2. Mole weight: 234.338. | |
| Axinysone B | Axinysone B is a metabolite of the mushroom Anthracophyllum sp. BCC18695. Synonyms: (-)-Axinysone B; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-4-hydroxy-1,1,7,7a-tetramethyl-, (1aS,4R,7S,7aS,7bR)-. Grade: 98.0%. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Synonyms: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. Grade: ≥98%. CAS No. 319460-85-0. Molecular formula: C22H18N4OS. Mole weight: 386.5. | |
| Axitinib | Inhibits VEGFR1, VEGFR2, VEGFR3, c-kit and PDGFR tyrosine kinases. Category: Active pharmaceutical ingredients. CAS No. 319460-85-0. Product ID: API319460850. Molecular formula: C22H18N4OS. Mole weight: 386.47. |  |
| Axitinib | Axitinib. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Highly Purified. CAS No. 319460-85-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H18N4OS. US Biological Life Sciences. | Worldwide |
| Axitinib | Axitinib is a multi-targeted tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-013736. CAS No. 319460-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10065. | |
| Axitinib-[13C,d3] | Axitinib-[13C,d3] is a labelled Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: [13C,2H3]-N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; (E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Grade: > 98%. CAS No. 1261432-00-1. Molecular formula: C21[13C]H15D3N4OS. Mole weight: 390.48. | |
| Axitinib Acid (Axitinib Impurity 37) | Axitinib Acid (Axitinib Impurity 37). Uses: For analytical and research use. CAS No. 319462-34-5. Molecular formula: C21H15N3O2S. Mole weight: 373.43. Catalog: APB319462345. |  |
| Axitinib (AG-013736) | Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively. Group: Inhibitors. Alternative Names: AG 013736. CAS No. 319460-85-0. Pack Sizes: 50mg. Product ID: S1005. Formula: C22H18N4OS. Smiles: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Axitinib-d3 | Labeled analogue of Axitinib, a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. Group: Biochemicals. Alternative Names: N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Axitinib-d3 | Axitinib-d3 (AG-013736-d3) is deuterium labeled Axitinib. Axitinib is a multi-targeted tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-013736-d3. CAS No. 1126623-89-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-10065S1. | |
| Axitinib-[d3] | Axitinib-[d3] is the labelled analogue of Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: Axitinib D3; N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3; Axitinib-d3 (N-methyl-d3). Grade: 95% by HPLC; 98% atom D. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. | |
| Axitinib-D3 (Axitinib Impurity 36) | Axitinib-D3 (Axitinib Impurity 36). Uses: For analytical and research use. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. Catalog: APB1126623899. | |
| Axitinib Impurity 1 | Axitinib Impurity 1 is an impurity of Axitinib, a drug primarily used in the treatment of advanced renal cell carcinoma and metastatic thyroid cancer. Synonyms: Axitinib Impurity c. Grade: > 95%. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.48. | |
| Axitinib Impurity 10 | Axitinib Impurity 10. Uses: For analytical and research use. Alternative Names: (E)-N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 1443118-72-6. Molecular formula: C29H25N5OS. Mole weight: 491.61. Catalog: APB1443118726. | |
| Axitinib Impurity 11 | Axitinib Impurity 11. Uses: For analytical and research use. Alternative Names: 2-((1-acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. CAS No. 1639138-00-3. Molecular formula: C17H14IN3O2S. Mole weight: 451.28. Catalog: APB1639138003. | |
| Axitinib Impurity 12 | Axitinib Impurity 12. Uses: For analytical and research use. Alternative Names: 2-((1H-indazol-6-yl)sulfinyl)-N-methylbenzamide. CAS No. 1959572-97-4. Molecular formula: C15H13N3O2S. Mole weight: 299.35. Catalog: APB1959572974. | |
| Axitinib Impurity 13 | Axitinib Impurity 13. Uses: For analytical and research use. Alternative Names: 2-((3-iodo-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide. CAS No. 1443118-71-5. Molecular formula: C15H12IN3O2S. Mole weight: 425.24. Catalog: APB1443118715. | |
| Axitinib Impurity 14 | Axitinib Impurity 14. Uses: For analytical and research use. Alternative Names: 2-((3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. CAS No. 885126-34-1. Molecular formula: C15H12IN3OS. Mole weight: 409.24. Catalog: APB885126341. | |
| Axitinib Impurity 15 | Axitinib Impurity 15. Uses: For analytical and research use. Alternative Names: (Z)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.47. Catalog: APB885126409. | |
| Axitinib Impurity 15 | Axitinib Impurity 15. Uses: For analytical and research use. CAS No. 1428728-84-0. Molecular formula: C44H36N8O2S2. Mole weight: 772.94. Catalog: APB1428728840. | |
| Axitinib Impurity 16 | Axitinib Impurity 16. Uses: For analytical and research use. Alternative Names: 2-((1-acetyl-1H-indazol-6-yl)thio)-N-methylbenzamide. Molecular formula: C17H15N3O2S. Mole weight: 325.38. Catalog: APB01212. | |
| Axitinib Impurity 17 | Axitinib Impurity 17. Uses: For analytical and research use. Alternative Names: N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 2749797-54-2. Molecular formula: C22H20N4OS. Mole weight: 388.49. Catalog: APB2749797542. | |
| Axitinib Impurity 18 | Axitinib Impurity 18. Uses: For analytical and research use. Alternative Names: 2,2'-(1H,1'H-[3,3'-biindazole]-6,6'-diylbis(sulfanediyl))bis(N-methylbenzamide). Molecular formula: C30H24N6O2S2. Mole weight: 564.68. Catalog: APB02755. | |
| Axitinib Impurity 19 | Axitinib Impurity 19. Uses: For analytical and research use. Alternative Names: 1H-indazole-4,6-diamine. CAS No. 885518-52-5. Molecular formula: C7H8N4. Mole weight: 148.17. Catalog: APB885518525. | |
| Axitinib Impurity 19 | Axitinib Impurity 19. Uses: For analytical and research use. CAS No. 319462-41-4. Molecular formula: C21H16N4OS. Mole weight: 372.48. Catalog: APB319462414. | |
| Axitinib Impurity 2 | Axitinib Impurity 2. Uses: For analytical and research use. Alternative Names: 2,2'-((3,3'-(2,4-di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). CAS No. 1428728-83-9. Molecular formula: C44H36N8O2S2. Mole weight: 772.94. Catalog: APB1428728839. | |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). Grade: > 95%. CAS No. 1428728-83-9. Molecular formula: C44H36N8O2S2. Mole weight: 772.96. | |
| Axitinib Impurity 20 | Axitinib Impurity 20. Uses: For analytical and research use. CAS No. 850568-25-1. Molecular formula: C12H11BN2O3. Mole weight: 242.04. Catalog: APB850568251. | |
| Axitinib Impurity 20 | Axitinib Impurity 20. Uses: For analytical and research use. Alternative Names: 6-nitro-1-nitroso-1H-indazole. Molecular formula: C7H4N4O3. Mole weight: 192.13. Catalog: APB02754. | |
| Axitinib Impurity 21 | Axitinib Impurity 21. Uses: For analytical and research use. CAS No. 6515-13-5. Molecular formula: C8H9N. Mole weight: 119.17. Catalog: APB6515135. | |
| Axitinib Impurity 21 | Axitinib Impurity 21. Uses: For analytical and research use. Alternative Names: 2,2'-disulfanediylbis(N-methylbenzamide). CAS No. 2527-58-4. Molecular formula: C16H16N2O2S2. Mole weight: 332.44. Catalog: APB2527584. | |
| Axitinib Impurity 22 | Axitinib Impurity 22. Uses: For analytical and research use. Alternative Names: 2-((2-(methylcarbamoyl)phenyl)disulfanyl)benzoic acid. Molecular formula: C15H13NO3S2. Mole weight: 319.40. Catalog: APB02753. | |
| Axitinib Impurity 23 | Axitinib Impurity 23. Uses: For analytical and research use. Alternative Names: (E)-1-(6-iodo-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-1-yl)ethanone. Molecular formula: C16H12IN3O. Mole weight: 389.19. Catalog: APB02751. | |
| Axitinib Impurity 23 | Axitinib Impurity 23. Uses: For analytical and research use. CAS No. 1443118-75-9. Molecular formula: C23H20N4O2S2. Mole weight: 448.56. Catalog: APB1443118759. | |
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