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| Product | Description | |
|---|---|---|
| Aprepitant Impurity A Enantiomer | Aprepitant Impurity A Enantiomer is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2. Mole weight: 527.47. |  |
| Aprepitant Impurity B Enantiomer HCl | A metabolite of Aprepitant. Synonyms: (2R,3S)-4-benzyl-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grade: > 95%. CAS No. 183901-47-5. Molecular formula: C27H24F7NO2. HCl. Mole weight: 527.49 36.46. | |
| Aprepitant Impurity B HCl | Aprepitant Impurity B HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C27H24F7NO2.HCl. Mole weight: 563.93. | |
| Aprepitant-M3 Metabolite | Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grade: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| Aprepitant N-Oxide | Aprepitant N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00838. Format: Neat. |  |
| Aprepitant open ring methyl ester | Aprepitant open ring methyl ester is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant; Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester; Methyl 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylate; Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)-1-iminoethyl)hydrazine-1-carboxylate; Aprepitant Open-Ring Methyl Ester Impurity. Grade: ≥95%. CAS No. 219821-37-1. Molecular formula: C24H25F7N4O4. Mole weight: 566.48. | |
| Aprepitant Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Aprepitant Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Apricitabine | Apricitabine is a highly selective and orally active HIV-1 reverse transcriptase (RT) inhibitor (Ki = 0.08 μM), with Kis of 300, 12 and 112.25 μM against DNA polymerase α, β and γ, respectively. It has been used in trials studying the treatment of HIV Infections. Synonyms: Apricitabine; 160707-69-7; AVX754; AVX-754; SPD754; Apricitabine [INN]; BCH 10618; BCH-10618; SPD-754; (-)-dOTC; 4-Amino-1-((2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl)pyrimidin-2(1H)-one; 4-amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]pyrimidin-2-one; K1YX059ML1; SPD -754; BCH-10619; BCH-10652; BCH-10652, (-)-; AVX 754; (-)-2'-Deoxy-3'-oxa-4'-thiocytidine (apricitabine); 2(1H)-Pyrimid. Grade: 95%. CAS No. 160707-69-7. Molecular formula: C8H11N3O3S. Mole weight: 229.26. | |
| Apricot Kernel Oil | Light carrier oil made from the dried kernels of apricots. Has similar properties as almond oil. 100% pure. Rich in vitamin A & E and oleic & linoleic fatty acids. SAP Value: 180-200. Uses: Creams, lotions, makeup, face oils, color cosmetics, conditioners, skin treatments, hand creams. Additional or Alternative Names: PERSIC OIL;APRICOT KERNEL OIL;FEMA 2150;Oils,apricot;PRUNUS ARMENIACA (APRICOT) KERNEL OIL;Prunusarmeniacakerneloil,refined;APRICOT(PRUNUSARMENIACA)KERNELOIL;PERSICOILREFINED. Product Category: Heterocyclic Organic Compound. Appearance: Clear light yellow liquid, cold pressed, refined, characteristic mild odor. CAS No. 72869-69-3. Molecular formula: CAS: 72869-69-3. Product ID: ACM72869693. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Apricoxib | Apricoxib. Group: Biochemicals. Alternative Names: 4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide; 4-Methyl-2- (4-ethoxyphenyl) -1- (4-sulfamoylphenyl) pyrrole; CS 706; R 109339; TG 01. Grades: Highly Purified. CAS No. 197904-84-0. Pack Sizes: 10mg. Molecular Formula: C19H20N2O3S, Molecular Weight: 356.44. US Biological Life Sciences. |  Worldwide |
| Apricoxib | Apricoxib is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. Synonyms: CS-701; CS 701; CS701; TG01; TG 01; TG-01; R-109339, R 109339; R109339; Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-. CAS No. 197904-84-0. Molecular formula: C19H20N2O3S. Mole weight: 356.44. | |
| Apricoxib-d4 | Apricoxib-d4. Group: Biochemicals. Alternative Names: 4-[2-(4-Ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzenesulfonamide-d4; 4-Methyl-2- (4-ethoxyphenyl) -1- (4-sulfamoylphenyl) pyrrole-d4; CS 706-d4; R 109339-d4; TG 01-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H16D4N2O3S, Molecular Weight: 360.46. US Biological Life Sciences. | Worldwide |
| Aprifloren® | Aprifloren®. CAS No. 67663-01-8. FEMA No. 3999. VIGON Item # 504567. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, 5-Hexyl-4-methyl-dihydro-furan-2-one, 5-Hexyldihydro-4-methylfuran-2(3H)-one |  America & Internationally |
| APRIL from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| APRIL human | recombinant, expressed in Hi-5 Insect cells, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| APRIL, Soluble mouse | recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Aprindine | Aprindine is an arrhythmia inhibitor that stabilizes the cell membranes of heart muscle cells, thereby preventing abnormal electrical impulses from causing irregular heartbeats. In hematological toxicity studies, aprindine showed potential inhibitory effects on the replicative capacity of mouse and human blood cells at certain concentrations [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37640-71-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0236. |  |
| Aprindine | Aprindine is a Class 1b antiarrhythmic agent as a cardiac depressant used in arrhythmias. Uses: A cardiac depressant used in arrhythmias. Synonyms: N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine. Grade: ≥98%. CAS No. 37640-71-4. Molecular formula: C22H30N2. Mole weight: 322.48. | |
| Aprindine hydrochloride | Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine hydrochloride has inhibitory effects on Na+/Ca2+ exchanger currents, which is partly responsible for their antiarrhythmic and cardioprotective effects. Aprindine hydrochloride is widely used for trial and ventricular tachyarrhythmias research research. Uses: Scientific research. Group: Signaling pathways. CAS No. 33237-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0236A. | |
| Aprindine hydrochloride | Aprindine hydrochloride is a class I-b anti-arrhythmic agent and a hERG channel blocker with an IC50 of 0.23 μM. Aprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies. Synonyms: N1-(2,3-Dihydro-1H-inden-2-yl)-N3,N3-diethyl-N1-phenyl-1,3-propanediamine Hydrochloride; N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propanediamine; Amidonal; Aspenon; Compd 83846; Fibocil; Fiboran; MS 5075; NSC 284614; Ritmusin. Grade: 95%. CAS No. 33237-74-0. Molecular formula: C22H31ClN2. Mole weight: 358.95. | |
| Aprindine hydrochloride | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Aprindine Hydrochloride | Class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given orally. Group: Biochemicals. Alternative Names: N1-(2,3-Dihydro-1H-inden-2-yl)-N3,N3-diethyl-N1-phenyl-1,3-propanediamine Hydrochloride; N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propanediamine; Amidonal; Aspenon; Compd 83846; Fibocil; Fiboran; MS 5075; NSC 284614; Ritmusin. Grades: Highly Purified. CAS No. 33237-74-0. Pack Sizes: 50mg. Molecular Formula: C??H??ClN?, Molecular Weight: 358.95. US Biological Life Sciences. | Worldwide |
| Aprocitentan | Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC 50 s of 3.4 nM and 987 nM, and pA 2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-132577. CAS No. 1103522-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15895. | |
| a-Prodine hydrochloride | a-Prodine hydrochloride. Group: Biochemicals. Alternative Names: (3R,4S)-rel-1,3-dimethyl-4-phenyl-4-piperidinol 4-propanoate hydrochloride; cis-(±)-1,3-Dimethyl-4-phenyl-4-piperidinol propanoate hydrochloride; (±)-Alphaprodine hydrochloride. Grades: Highly Purified. CAS No. 561-78-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H24ClNO2. US Biological Life Sciences. | Worldwide |
| Apronal | Apronal (Allylisopropylacetylurea, Apronalide) can bu used for the research of neuropsychiatry disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Allylisopropylacetylurea; Apronalide. CAS No. 528-92-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2177. | |
| a-Propylphenylacetonitrile | Clear liquid, 97%. Synonyms: 2-Phenylpentanonitrile. CAS No. 5558-78-1. Pack Sizes: 5g, 25g. Product ID: FR-0337. B.P. 125-128/13 mm. Mole weight: 159.23. |  Frinton Laboratories |
| Aprotinin | Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with K i s of 0.06 pM and 9 nM, respectively. Uses: Scientific research. Group: Peptides. CAS No. 9087-70-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0017. | |
| Aprotinin | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue sample | |
| Aprotinin | Aprotinin Inhibitor. Uses: Scientific use. Product Category: T3359. CAS No. 9087-70-1. |  |
| Aprotinin | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C284H432N84O79S7. CAS No. 9087-70-1. Prepack ID 16927557-25mg. Molecular Weight 6511.45. See USA prepack pricing. |  |
| Aprotinin, Bovine (Pancreatic trypsin inhibitor) | Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes, dissociating at pH >10 or <3. Effective concentration is equimolar with protease. Group: Biochemicals. Alternative Names: Antikrein; Antilysin; Antilysine; Aprostat; Aprotinin; BPTI; BPTI Trypsin Inhibitor; Basic Pancreatic Trypsin Inhibitor; Bayer A 128; Bovine Basic Pancreatic Trypsin Inhibitor; Bovine Pancreatic Trypsin Inhibitor; Bovine Trypsin Inhibitor; Fosten; Kallikrein-trypsin Inactivator; Kiker 52G; Kir Richter; Kunitz Pancreatic Trypsin Inhibitor; Kunitz Protease Inhibitor; Kunitz Trypsin Inhibitor; Kunitz-type Inhibitor; Kunitz-type Proteinase Inhibitor; Kunitz-type Trypsin Inhibitor; Onquinin; Pancreatic Basic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor; Pancreatic Trypsin Inhibitor (Kunitz); Protease Inhibitor, Kunitz Type; RP 9921; Repulson; Trasuylol; Trasylol; Trazinin; Triazinin; Trypsin Inhibitor, Trasylol; Trypsin-kallikrein Inhibitor (Kunitz); Zymofren. Grades: Highly Purified. CAS No. 9087-70-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C???H???N??O??S?, Molecular Weight: 6511.45. US Biological Life Sciences. | Worldwide |
| Aprutumab | Aprutumab is a humanized monoclonal antibody directed against FGFR2. Aprutumab has been used in the research of solid tumors. Synonyms: BAY 1179470; BAY-1179470; BAY1179470. CAS No. 1634620-63-5. | |
| APS-2-79 | APS-2-79 is a small molecule antagonist of MEK phosphorylation by RAF through direct binding of the KSR active site, and antagonizes oncogenic Ras signalling (IC50 value 120 nM against ATP-biotin probe-labelling of KSR2). Synonyms: 6,7-Dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine; APS-2-79; APS 2-79; APS2-79; APS-279; APS 279; APS279. CAS No. 2002381-25-9. Molecular formula: C23H21N3O3. Mole weight: 387.43. | |
| APS-2-79 HCl | APS-2-79 is a MAPK antagonist which can modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization and the conformational changes required for phosphorylation and activation of KSR-bound MEK. APS-2-79 was found to bind to the KSR active site with an IC50 value of 120 nM, antagonizing MEK (MAPKK) phosphorylation by RAF. Synonyms: APS-2-79 HCl; APS2-79 HCl; APS 2-79 HCl; APS-279 HCl; APS279 HCl; APS 279 HCl; SCHEMBL18153640; AKOS032944984; CS-6151; 6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine; hydrochloride. Grade: 99.26 %. CAS No. 2002381-31-7. Molecular formula: C23H21N3O3.HCl. Mole weight: 423.89. | |
| APS-2-79 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| APS6-45 | APS6-45 is an orally active tumor-calibrated inhibitor (TCI) that strongly inhibits RAS pathway signaling in human MTC cell lines TT and MZ-CRC-1. Synonyms: 4-(4-(3-(2-fluoro-5-(perfluoropropan-2-yl)phenyl)ureido)phenoxy)-N-methylpicolinamide; APS645; APS6 45; APS-645; APS 645. Grade: >98%. CAS No. 2188236-41-9. Molecular formula: C23H16F8N4O3. Mole weight: 548.39. | |
| APS sodium salt | APS is an active sulfate ester of 5'-AMP, which is used in pyrosequencing and bioluminescence applications. Synonyms: Adenosine- 5'- O- phosphosulfate, sodium salt. Grade: 85%. CAS No. 102029-95-8. Molecular formula: C10H14N5O10PS (free acid). Mole weight: 427.3 (free acid). | |
| Aptazapine | Aptazapine is a tetracyclic antidepressant. It was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. Aptazapine is a α2-adrenergic receptor antagonist. It is also a 5-HT2 receptor antagonist and H1 receptor inverse agonist, while having no significant effects on the reuptake of serotonin or norepinephrine. Uses: Antidepressant. Synonyms: CGS 7525 A; 2-methyl-1,3,4,14b-tetrahydro-2H,10H-benzo[e]pyrazino[2,1-c]pyrrolo[1,2-a][1,4]diazepine; 71576-41-5 (maleate). Grade: 98%. CAS No. 71576-40-4. Molecular formula: C16H19N3. Mole weight: 253.35. | |
| Aptazapine maleate | Aptazapine is a tetracyclic antidepressant. It was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. Aptazapine is a α2-adrenergic receptor antagonist. It is also a 5-HT2 receptor antagonist and H1 receptor inverse agonist, while having no significant effects on the reuptake of serotonin or norepinephrine. Uses: Antidepressant. Synonyms: (+-)-1,3,4,14b-Tetrahydro-2-methyl-2H,10H-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)benzodiazepine maleate (1:1). Grade: 98%. CAS No. 71576-41-5. Molecular formula: C16H19N3.C4H4O4. Mole weight: 369.42. | |
| Aptiganel hydrochloride | Aptiganel hydrochloride (Cerestat) is a non-competitive NMDA receptor antagonist with neuroprotective effect. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CNS 1102. CAS No. 137160-11-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110097. | |
| APTO-253 | APTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krüppel-like factor 4 (KLF4) tumor suppressor[1][2]. APTO-253 has antiarthritic activity[3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOR-253; LT-253. CAS No. 916151-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16291. | |
| APTO-253 hydrochloride | APTO-253, also known as LOR-253, LT-253, is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and proliferation. This agent also causes decreased expression of genes involved in tumor hypoxia and angiogenesis. Synonyms: APTO 253 hydrochloride; APTO253 hydrochloride; LOR253 hydrochloride; LOR-253 hydrochloride; LOR 253 hydrochloride. CAS No. 1422731-37-0. Molecular formula: C22H15ClFN5. Mole weight: 403.85. | |
| APTS | APTS. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Aminopyrene-1,3,6-trisulfonicacid,trisodiumsalt. Product Category: Other Fluorophores. Appearance: Yellow solid. CAS No. 196504-57-1. Molecular formula: C16H8N3O9S3. Mole weight: 523.4. Purity: 95%+. IUPACName: Trisodium;8-aminopyrene-1,3,6-trisulfonate. Canonical SMILES: C1=CC2=C3C(=C(C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])C=CC4=C(C=C(C1=C43)N)S(=O)(=O)[O-].[Na+].[Na+].[Na+]. Product ID: ACM196504571-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| APTS@ Fe2O3 Nanoparticles | APTS@ Fe2O3 Nanoparticles. Group: Nanopowders. CAS No. 1317-61-9. |  |
| APTSTAT3-9R | APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating motif. STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. The treatment of APTSTAT3-9R in various types of cancer cells blocks STAT3 phosphorylation and reduces expression of STAT targets. Treatment of various types of cancer cells with APTSTAT3-9R blocked STAT3 phosphorylation and reduced expression of STAT targets, including cyclin D1, Bcl-xL, and survivin. As a result, APTSTAT3-9R suppressed the viability and proliferation of cancer cells. Furthermore, intratumoral injection of APTSTAT3-9R exerted potent antitumor activity in both xenograft and allograft tumor models. Synonyms: H-DL-His-Gly-DL-Phe-DL-Gln-DL-Trp-DL-Pro-Gly-DL-Ser-DL-Trp-DL-xiThr-DL-Trp-DL-Glu-DL-Asn-Gly-DL-Lys-DL-Trp-DL-xiThr-DL-Trp-DL-Lys-Gly-DL-Ala-DL-Tyr-DL-Gln-DL-Phe-DL-Leu-DL-Lys-Gly-Gly-Gly-Gly-DL-Ser-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-DL-Arg-OH; HGFQWPGSWXWENGKWXWKGAYQFLKGGGGSRRRRRRRRR; DL-histidyl-glycyl-DL-phenylalanyl-DL-glutaminyl-DL-tryptophyl-DL-prolyl-glycyl-DL-seryl-DL-. Grade: 99.31 %. Molecular formula: C223H330N80O51. Mole weight: 4947.51. | |
| APX001A | APX001A is a first-in-class small-molecule inhibitor of the conserved fungal Gwt1 protein. APX001A is active against the major fungal pathogens, i.e., Candida (except Candida krusei), Aspergillus, and hard-to-treat molds, including Fusarium and Scedosporium. Synonyms: MGX; Manogepix; E1210. CAS No. 936339-60-5. Molecular formula: C21H18N4O2. Mole weight: 358.39. | |
| APX-115 | APX-115 is a first-in-class pan-NADPH oxidase (Nox) inhibitor. Study shows that APX-115 might be a promising therapeutic agent for the treatment of diabetic nephropathy because of its pan-NOX inhibitory activity, including its NOX5 inhibitory activity, and also owing to its anti-inflammatory effect. Synonyms: Ewha-18278; Isuzinaxib hydrochloride; 3-Phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol hydrochloride. Grade: 99%. CAS No. 1395946-75-4. Molecular formula: C17H17N3O.HCl. Mole weight: 315.80. | |
| APX-115 | APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 ?M, 0.57 ?M, and 0.63 ?M for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ewha-18278. CAS No. 1395946-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120801. | |
| APX2009 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| APY0201 | APY0201 Inhibitor. Uses: Scientific use. Product Category: T2061. CAS No. 1232221-74-7. | |
| APY0201 | APY0201, an effective IL-12/23 inhibitor, has been found to have potential use in the treatment of inflammation. IC50 = 5.2 nM. Synonyms: APY0201; APY-0201; APY 0201. Grade: 98%. CAS No. 1232221-74-7. Molecular formula: C23H23N7O. Mole weight: 413.48. | |
| APY0201 | APY0201 is a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5.2 nM. APY0201 also inhibits IL-12/IL-23 production. Uses: Scientific research. Group: Signaling pathways. CAS No. 1232221-74-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15982. | |
| APY29 | Allosteric modulator of IRE1α. Inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α ribonuclease activity. Synonyms: APY29; APY-29; APY 29; N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine. Grade: >98%. CAS No. 1216665-49-4. Molecular formula: C17H16N8. Mole weight: 332.36. | |
| APY29 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| APY29 | APY29, an ATP-competitive inhibitor, is an allosteric modulator of IRE1? which inhibits IRE1? autophosphorylation by binding to the ATP-binding pocket with IC50 of 280 nM. APY29 acts as a ligand that allosterically activates IRE1? adjacent RNase domain[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216665-49-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17537. | |
| APY 29 | APY 29. Group: Biochemicals. Grades: Purified. CAS No. 1216665-49-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Apyramide | Apyramide is a non-steroidal anti-inflammatory agent (NSAID) that is a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable, non-selective inhibitor of COX1 and COX2. Synonyms: 4-(Acetylamino)phenyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate; 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-p-acetamidophenol acetate; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 4-(acetylamino)phenyl ester; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 4-(acetylamino)phenyl ester. Grade: ≥95%. CAS No. 68483-33-0. Molecular formula: C27H23ClN2O5. Mole weight: 490.93. | |
| apyrase | Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyse NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates. They differ from ATPases, which specifically hydrolyse ATP, by hydrolysing both ATP and ADP. The eukaryotic enzymes requires Ca2+, but Mg2+ can substitute. Most of the ecto-ATPases that occur on the cell surface and hydrolyse extracellular nucleotides belong to this enzyme family. Group: Enzymes. Synonyms: ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase [ambiguous]. Enzyme Commission Number: EC 3.6.1.5. CAS No. 9000-95-7. Apyrase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4623; apyrase; EC 3.6.1.5; 9000-95-7; ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase [ambiguous]. Cat No: EXWM-4623. |  |
| Apyrase | Apyrase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-95-7. Pack Sizes: 10 U; 100 U. Product ID: HY-P2764. | |
| Apyrase from Potato, Recombinant | Apyrase is found in all eukaryotes and some prokaryotes. Apyrase, from potato, has a crucial role in regulating growth and development. Apyrase is involved in the inactivation of synaptic ATP as a neurotransmitter following nerve stimulation and in the inhibition of ADP induced platelet aggregation to prevent thrombosis. Divalent metal ions are required for activity and best activity is observed with calcium ion at 5 mM. Apyrase (recombinant, e. coli) is a highly active atp-diphosphohydrolase that catalyses the sequential hydrolysis of atp to adp and adp to amp releasing inorganic phosphate. it is a recombinant version of one of several isoforms of apyrase. it can also hydrol...version of 5? triphosphorylated rna to ligatable monophosphorylated form that can be used for 5? rna adaptor ligation. conversion of 5? triphosphorylated rna to 5? exonuclease xrn-1 sensitive monophosphorylated rna. Group: Enzymes. Synonyms: ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase; apyrase; EC 3.6.1.5; 9000-95-7. Apyrase. Mole weight: 47 kDa. Activity: 3,000 units/mg. Storage: at -20°C. Form: 50 mM NaCl, 20 mM MES (pH 6.5 25°C), 0.1 mM CaCl2, 1 mM DTT, 0.1% Tween-20 and 50% glycerol. Source: E. coli. Species: Potato. ATP-diphosphatase; adenosine diphosphatase; ADPase; ATP diphosphohydrolase; apyrase; EC 3.6.1.5; 9000-95-7. Cat No: NATE-1268. | |
| AQ-13 dihydrochloride | AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum. Uses: Scientific research. Group: Signaling pathways. CAS No. 169815-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100358. | |
| AQ4 | AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-9,10-anthraquinone, 70476-63-0, 72758-40-8, 1,4-Bis((2-(dimethylamino)ethyl)amino)-5,8-dihydroxyanthracene-9,10-dione, 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione, 1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione, AC1L36GN, AC1Q6J6J, SureCN3148984, CTK8D7828, KST-1B8141, AR-1B7623, 1,4-bis(2-dimethylaminoethylamino)-5,8-dihydroxyanthracene-9,10-dione, 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione, 9,10-Anthracenedione, 1,4-bis((2-(dimethylamino)ethyl)amino)-5,8-dihydroxy-. Product Category: Inhibitors. CAS No. 70476-63-0. Molecular formula: C22H28N4O4. Mole weight: 412.48. Purity: 0.96. IUPACName: 1,4-bis[2-(dimethylamino)ethylamino]-5,8-dihydroxyanthracene-9,10-dione. Canonical SMILES: CN(C)CCNC1=C2C(=C(C=C1)NCCN(C)C)C(=O)C3=C(C=CC(=C3C2=O)O)O. Product ID: ACM70476630. Alfa Chemistry ISO 9001:2015 Certified. Categories: AQ400. | |
| AQ4 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AQC | AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate. CAS No. 148757-94-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-117695. | |
| AQ-RA 741 | AQ-RA 741. Group: Biochemicals. Alternative Names: 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grades: Highly Purified. CAS No. 123548-16-3. Pack Sizes: 10mg. Molecular Formula: C27H37N5O2, Molecular Weight: 463.61. US Biological Life Sciences. | Worldwide |
| AQ-RA 741 | AQ-RA 741 has been found to be a muscarinic M2 receptor antagonist and could probably be used in the development of bronchodilator anti-muscarinic agent. Synonyms: 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grade: ≥99% by HPLC. CAS No. 123548-16-3. Molecular formula: C27H37N5O2. Mole weight: 463.62. | |
| aquacobalamin reductase | A flavoprotein. Group: Enzymes. Synonyms: aquocobalamin reductase; vitamin B12a reductase; NADH-linked aquacobalamin reductase; B12a reductase; NADH2:cob(III)alamin oxidoreductase. Enzyme Commission Number: EC 1.16.1.3. CAS No. 37256-39-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1068; aquacobalamin reductase; EC 1.16.1.3; 37256-39-6; aquocobalamin reductase; vitamin B12a reductase; NADH-linked aquacobalamin reductase; B12a reductase; NADH2:cob(III)alamin oxidoreductase. Cat No: EXWM-1068. | |
| aquacobalamin reductase (NADPH) | A flavoprotein. Acts on aquacob(III)alamin and hydroxycobalamin, but not on cyanocobalamin. Group: Enzymes. Synonyms: aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-linked aquacobalamin reductase; NADPH2:aquacob(III)alamin oxidoreductase. Enzyme Commission Number: EC 1.16.1.5. CAS No. 110777-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1070; aquacobalamin reductase (NADPH); EC 1.16.1.5; 110777-32-7; aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-linked aquacobalamin reductase; NADPH2:aquacob(III)alamin oxidoreductase. Cat No: EXWM-1070. | |
| Aqua Graphene slurry | Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;Black | |
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