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| Product | Description | |
|---|---|---|
| AS-186c | AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Alternative Names: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82. |  |
| AS-186d | AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Alternative Names: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86. | |
| AS 1892802 | AS 1892802. Group: Biochemicals. Grades: Purified. CAS No. 928320-12-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| AS 19 | Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced. Group: Biochemicals. Alternative Names: (2S) - (+) -5- (1, 3, 5-Trimethylpyrazol-4-yl) -2- (dimethylamino) tetralin. Grades: Highly Purified. CAS No. 1000578-26-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 283.41. US Biological Life Sciences. | Worldwide |
| AS1949490 | AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 μM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1203680-76-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18686. |  |
| AS 1949490 | AS 1949490. Group: Biochemicals. Grades: Purified. CAS No. 1203680-76-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS 2034178 | AS 2034178. Group: Biochemicals. Grades: Purified. CAS No. 1030846-42-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS 252424 | AS 252424. Group: Biochemicals. Grades: Purified. CAS No. 900515-16-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AS-252424 | AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 900515-16-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13532. | |
| AS-254s | AS-254s is the inhibitor for absent, small, or homeotic-like 1 protein (ASH1L) with an IC50 of 94 nM (FP assay). AS-254s exhibits antiproliferative activity against MLL1-rearranged leukemic cells with GI50 <1 μM. AS-254s induces the differentiation of MLL1-r leukemic cell[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3096805-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-170494. | |
| AS2717638 | AS2717638 is a highly selective, brain-penetrant and orally active lysophosphatidic acid receptor 5 (LPA5) antagonist with an IC50 value of 38 nM. AS2717638 is highly selective and shows no significant antagonistic activity against other LPA receptors (LPA1, LPA2, and LPA3). AS2717638 can be used in the research of pain and neuroinflammation-related diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2148339-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114379. | |
| AS2863619 | AS2863619 is a small-molecule cyclin-dependent kinase CDK8/19 inhibitor with IC50 of 0.6099 nM and 4.277 nM, respectively. AS2863619 is a potent Foxp3 inducer in Tconv cells. Group: Inhibitors. CAS No. 2241300-51-4. Pack Sizes: 2mg. Product ID: S8903. Formula: C16H14Cl2N8O. Smiles: CC1=NC2=C(N1)C=C(C=C2)N3C4=C(C=NC=C4)N=C3C5=NON=C5N.Cl.Cl. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| AS2863619 | AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241300-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126675A. | |
| AS2863619 free base | AS2863619 free base enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 free base is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241300-50-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126675. | |
| As48 | As48 is a selective TREM2 agonist with a KD value of 12.48 μM in TRIC binding assay. As48 binds near the TREM2 cleavage region, forms hydrogen bonds with Gly68, reduces conformational flexibility in regions 58-102, restricts protease accessibility to the cleavage site. As48 activates SYK phosphorylation, enhances microglial phagocytosis, and induces downstream calcium signaling in TREM2-expressing cells. As48 inhibits TREM2 ectodomain shedding without affecting ADAM10/17 protease activities. As48 can be used for the research of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1214405-38-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-182702. | |
| AS601245 | AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 345987-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11010. | |
| AS601245 | Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| AS-604850 | AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα. Alternative Names: AS604850; AS 604850; AS-604850. PI3K gamma inhibitor; PI 3-Kgamma Inhibitor II; (5E)-5-[(2,2-Difluoro-1,3-benzodioxol-5-YL)methylene]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 648449-76-7. Molecular formula: C11H5F2NO4S. Mole weight: 285.211. | |
| AS 605240 | AS 605240. Group: Biochemicals. Grades: Purified. CAS No. 648450-29-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS-605240 | AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC50 of 8 nM, and a Ki of 7.8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 648450-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10109. | |
| AS8351 | AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC51355. CAS No. 796-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100744. | |
| AS 8351 | AS 8351 has been found to show the activity in inducing reprogramming of human fetal lung fibroblasts into functional cardiomyocytes. Alternative Names: AS-8351; AS-8351; AS-8351; 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone. Grades: ≥98% by HPLC. CAS No. 796-42-9. Molecular formula: C17H13N3O2. Mole weight: 291.30. | |
| AS-99 TFA | AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3115178-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141429A. | |
| Asacoumarin A | Asacoumarin A. Alternative Names: 7-[(2E,6Z)-5,8- dihydroxy-3,7,11-trimethyldodeca-2,6,10-trienoxy]chromen-2-one. CAS No. 122617-02-1. Purity: >95.0%. Product ID: FFC-AR-122617021. Molecular formula: C24H30O5. Mole weight: 398.49. IUPAC Name: 7-(5,8-dihydroxy-3,7,11-trimethyldodeca-2,6,10-trienoxy)chromen-2-one. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Asapiprant | Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-555739. CAS No. 932372-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16763. | |
| Asarinin | Asarinin. Group: Biochemicals. Alternative Names: (-)-Episesamin. Grades: Plant Grade. CAS No. 133-04-0. Pack Sizes: 20mg. Molecular Formula: C20H18O6, Molecular Weight: 354.353. US Biological Life Sciences. | Worldwide |
| Asarinin | Asarinin, isolated from the herbs of Asarum sieboldii Miq, decreased peripheral blood concentration of IL-12 and inhibited the expression of TLR4 and CXCR3, which means Asarinin may have a role on TLR4 pathway and produced prolongation of allograft heart survival. Alternative Names: 1,3-Benzodioxole, 5,5'-[(1R,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis-, rel-; L-Asarinin. Grades: >98%. CAS No. 133-05-1. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| Asarinin | Asarinin. Group: Biochemicals. CAS No. 133-04-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Asarone | Asarone. Group: Biochemicals. Grades: Plant Grade. CAS No. 2883-98-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asarylaldehyde | Asarylaldehyde. Alternative Names: Asaronaldehyde, Asaraldehyde, Azarylaldehyde, Gazarin, 2,4,5-TRIMETHOXYBENZALDEHYDE, Spectrum_000818, 3,4,6-Trimethoxybenzaldehyde, Benzaldehyde, 2,4,5-trimethoxy-, Spectrum2_000386, Spectrum3_000170, Spectrum4_001759, Spectrum5_000618, CCRIS 1296, BSPBio_001639, KBioGR_002238, KBioSS_001298, SPECTRUM200208, HSDB 4502, MLS002473312, SPBio_000571. CAS No. 14374-62-0. Purity: 96%. Product ID: ACM14374620. Molecular formula: C10H12O4. Mole weight: 196.19988. IUPAC Name: 2,4,5-trimethoxybenzaldehyde. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Asarylaldehyde | Asarylaldehyde. Group: Biochemicals. Grades: Plant Grade. CAS No. 4460-86-0, 14374-62-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asatone | Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38451-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6826. | |
| ASB14780 | ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1069046-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119019. | |
| ASC-69 | ASC-69 (APY69)is a potent and promising?PD-1/PD-L1 small-molecule inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APY69. CAS No. 1216665-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W771599. | |
| Ascalin | Ascalin is produced by Allium cepa var. aggregatum. It has antifungal activity against B.cinerea. Ascalin also inhibits HIV-1 reverse transcriptase with an IC50 of 10 μM. | |
| Ascamycin | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. The MIC values of Ascamycin against Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei are 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL, respectively. Alternative Names: (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine; 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine; 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine; 5'-O-{[(2S)-2-Amino-1-hydroxypropylidene]sulfamoyl}-2-chloroadenosine. Grades: ≥95%. CAS No. 91432-48-3. Molecular formula: C13H18ClN7O7S. Mole weight: 451.84. | |
| Ascaphin-1 | Ascaphin-1 is produced by Ascaphus truei. Ascaphin-1 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-1M | Ascaphin-1M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-2 | Ascaphin-2 is isolated from norepinephrine-stimulated skin secretions of A. truei and was shown to possess growth inhibitory activity against Escherichia coli and Staphylococcus aureus. | |
| Ascaphin-3 | Ascaphin-3 is produced by Ascaphus truei. Ascaphin-3 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-3M | Ascaphin-3M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-4 | Ascaphin-4 is produced by Ascaphus truei. Ascaphin-4 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-4M | Ascaphin-4M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-5 | Ascaphin-5 is produced by Ascaphus truei. Ascaphin-5 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-5M | Ascaphin-5M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Alternative Names: Gly-Ile-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Thr-Leu-Ile-Lys-Thr-Val-Ala-Ser-His-Ile-Ala-Asn-Gln. Grades: >98%. Molecular formula: C116H195N33O32. Mole weight: 2564.03. | |
| Ascaphin-6 | Ascaphin-6 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Alternative Names: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Glu; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamic acid. Grades: >98%. CAS No. 722538-44-5. Molecular formula: C118H195N31O33. Mole weight: 2576.03. | |
| Ascaphin-7 | Ascaphin-7 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Alternative Names: H-Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Gln-OH; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grades: ≥98%. CAS No. 722538-45-6. Molecular formula: C118H196N32O32. Mole weight: 2575.04. | |
| Ascaphin-7M | Ascaphin-7M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Alternative Names: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Ser-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Asn-Ile-Ala-Asn-Gln; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-seryl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-asparaginyl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grades: >98%. Molecular formula: C120H199N33O33. Mole weight: 2632.11. | |
| Ascaphin-8 | Ascaphin-8 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows similar potency against Gram-negative bacteria and Gram-positive bacteria and has a high hemolytic activity. Alternative Names: Gly-Phe-Lys-Asp-Leu-Leu-Lys-Gly-Ala-Ala-Lys-Ala-Leu-Val-Lys-Thr-Val-Leu-Phe-NH2; glycyl-L-phenylalanyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-valyl-L-lysyl-L-threonyl-L-valyl-L-leucyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 722538-46-7. Molecular formula: C97H164N24O22. Mole weight: 2018.53. | |
| Ascaridole | An organic peroxide which constitutes 60-80% of oil of chenopodium. Anthelmintic. Group: Biochemicals. Alternative Names: 1-Methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene. Grades: Highly Purified. CAS No. 512-85-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Ascaridole | Ascaridole is an anthelmintic and also has antimalarial activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 512-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-118494. | |
| Asciminib | Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Uses: Tyrosine kinase inhibitors. Alternative Names: ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide. CAS No. 1492952-76-7. Molecular formula: C20H18ClF2N5O3. Mole weight: 449.843. | |
| Asciminib | Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABL001. CAS No. 1492952-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010. | |
| Asciminib-[15N,d4] | Asciminib-[15N,d4] is the labelled analogue of Asciminib. Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Alternative Names: [15N,2H4]-Asciminib; (R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)nicotinamide[15N,2H4]. Molecular formula: C20H14D4ClF2N4[15N]O3. Mole weight: 454.86. | |
| Asciminib hydrochloride | Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABL001 hydrochloride. CAS No. 2119669-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010A. | |
| asclepain | From the latex of milkweed, Asclepias syriaca. It has multiple forms, and is in peptidase family C1 (papain family). Group: Enzymes. Enzyme Commission Number: EC 3.4.22.7. CAS No. 37288-80-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4246; asclepain; EC 3.4.22.7; 37288-80-5. Cat No: EXWM-4246. |  |
| Ascochin | Ascochin is a fungal metabolite found in Ascochyta, which has antifungal, antibacterial and phytotoxic activities. Alternative Names: (S)-(+)-Ascochin. Grades: >95% by HPLC. CAS No. 935699-58-4. Molecular formula: C12H10O5. Mole weight: 234.2. | |
| Ascochitine | Ascochitine is an antibiotic produced by Ascochita fabae and Asc. pisi. It is mainly resistant to fungi such as Xanthomonas oryzae and Xanthomonas oryzae, and has a control effect on some diseases of rice and tomato. Molecular formula: C15H16O5. Mole weight: 276.28. | |
| Ascochlorin | Ascochlorin is an antibiotic produced by Ascochyta viciae. It has anti-candida albicans activity. It can inhibit Newcastle disease virus and herpes simplex virus plaque formation in chicken embryo fibroblast culture. Alternative Names: Ilicicolin D. Grades: >98%. CAS No. 26166-39-2. Molecular formula: C23H29ClO4. Mole weight: 404.93. | |
| Ascochlorin (Antibiotic LL-Z 1272 gamma) | The antitumour fungal metabolite ascochlorin specifically inhibits matrix metalloproteinase-9 (MMP9) activity through suppression of activator protein-1 (AP-1) dependent induction of MMP-9 gene expression. Via AP-1 suppression ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses. Group: Biochemicals. Alternative Names: Antibiotic LL-Z 1272 gamma. Grades: Highly Purified. CAS No. 26166-39-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Ascofuranone | Ascofuranone is an antibiotic produced by Ascochyta viciae. On the agar plate, it can inhibit the plaque formation of some viruses, and is not resistant to bacteria and other microorganisms. Oral administration in rats can reduce blood lipids. Grades: >98%. CAS No. 38462-04-3. Molecular formula: C23H29ClO5. Mole weight: 420.93. | |
| Ascomatic acid | It is a new dibenzofuran and depside from the Lichen Bunodophoron patagonicum. Alternative Names: 2-Dibenzofurancarboxylic acid, 3,7-dimethoxy-1,9-dimethyl-; 3,7-dimethoxy-1,9-dimethyldibenzofuran-2-carboxylic acid. CAS No. 93796-74-8. Molecular formula: C17H16O5. Mole weight: 300.31. | |
| Ascomycin | Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells.Ascomycin (also known as Immunomycin, FR 900520, and FK-520) is an analog of tacrolimus (FK-506) with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases.Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells. Paul, C., et al. "Ascomycins: promising agents for the treatment of inflammatory skin diseases." Expert Opin. Investig. Drugs. 9: 69-77 (2000). Moll.the compounds." J. Infect. Dis. 191: 1342-1349 (2005).FK-520 might be a substrate for P-glycoprotein; expression of P-glycoprotein in yeast cells resulted in resistance to growth inhibition by FK-520. Raymond, M., et al. "Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520." Mol. Cell Biol. 14: 277-286 (1994). Group: Biochemicals. Alternative Names: Immunomycin; FK-520; FR-520; NSC-106410; FR 900520; L 683590; Changchuanmycin. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C43H69NO12, Molecular Weight: 792.01. US Biological Life Sciences. | Worldwide |
| Ascomycin | Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Immunomycin; FR-900520; FK520. CAS No. 104987-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg. Product ID: HY-13557. | |
| Ascophyllum nodosum extract | Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Ascophyllum nodosum, Fucaceae. Alternative Names: Fucoidan, ex ascophyllum nodosum; Ascophyllum nodosum, ext.; Stimax; Stimax Growth. CAS No. 84775-78-0. | |
| ascopyrone tautomerase | This enzyme catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose. The other enzymes involved in this pathway are EC 4.2.1.110 (aldos-2-ulose dehydratase), EC 4.2.1.111 (1,5-anhydro-D-fructose dehydratase) and EC 4.2.2.13 [exo-(1?4)-α-D-glucan lyase]. Ascopyrone P is an anti-oxidant. Group: Enzymes. Synonyms: ascopyrone isomerase; ascopyrone intramolecular oxidoreductase; 1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase; APM tautomerase; ascopyrone P tautomerase; APTM. Enzyme Commission Number: EC 5.3.2.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5487; ascopyrone tautomerase; EC 5.3.2.7; ascopyrone isomerase; ascopyrone intramolecular oxidoreductase; 1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase; APM tautomerase; ascopyrone P tautomerase; APTM. Cat No: EXWM-5487. | |
| ascorbate ferrireductase (transmembrane) | A diheme cytochrome that transfers electrons across a single membrane, such as the outer membrane of the enterocyte, or the tonoplast membrane of the plant cell vacuole. Acts on hexacyanoferrate(III) and other ferric chelates. Group: Enzymes. Synonyms: cytochrome b561 (ambiguous). Enzyme Commission Number: EC 7.2.1.3 (Formerly EC 1.16.5.1). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1077; ascorbate ferrireductase (transmembrane); EC 1.16.5.1; cytochrome b561 (ambiguous). Cat No: EXWM-1077. | |
| Ascorbate oxidase, Cucurbit sp. | Ascorbate oxidase, Cucurbit sp., also known as vitamin C oxidase, is a REDOX enzyme involved in the regulation of extracellular matrix. Ascorbate oxidase catalyzes the reaction of ascorbic acid and oxygen to produce dehydroascorbic acid[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASO, Cucurbit sp. CAS No. 9029-44-1. Pack Sizes: 100 U; 500 U; 1000 U. Product ID: HY-P2742. | |
| Ascorbic Acid | Ascorbic Acid. Grade: USP. CAS: 50-81-7. Packing: Box. |  New Jersey NJ |
| Ascorbic Acid | Ascorbic acid is a naturally occurring organic compound and a form of Vitamin C. It is water-soluble and found in high concentrations in many types of fruits and vegetables, especially citrus fruits such as oranges and lemons. It is used in some beauty and skincare products due to its antioxidant properties. Alternative Names: Ascoltin. CAS No. 50-81-7. Purity: 99%. Product ID: CI-SC-0578. Molecular formula: C6H8O6. Mole weight: 176.12 g/mol. IUPAC Name: (2R)-2-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one. Canonical SMILES: C(C(C1C(=C(C(=O)O1)O)O)O)O. Alfa Chemistry - ISO 9001:32057 Certified. | |
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