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| Product | Description | |
|---|---|---|
| Apigenin-7-diglucuronide | Apigenin-7-diglucuronide is a flavonoid glycoside and is present in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. Apigenin-7-diglucuronide protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation[1]. Uses: Scientific research. Category: Natural products. CAS No. 74696-01-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7270. |  |
| Apigenin 7-glucoside | Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigetrin. CAS No. 578-74-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0578. | |
| Apigenin-7-glucuronide | Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Apigenin 7-O-glucuronide. CAS No. 29741-09-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N1454. | |
| Apigenin 7-O- (2G-rhamnosyl) gentiobioside | Apigenin 7-O- (2G-rhamnosyl) gentiobioside. Group: Biochemicals. CAS No. 174284-20-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Apigenin-7-O - (2G-rhamnosyl) gentiobioside | Apigenin-7-O - (2G-rhamnosyl) gentiobioside. Group: Biochemicals. Alternative Names: Apigenin 7- (2G-rhamnosyl) gentiobioside. Grades: Plant Grade. CAS No. 174284-20-9. Pack Sizes: 10mg. Molecular Formula: C33H40O19, Molecular Weight: 740.66. US Biological Life Sciences. | Worldwide |
| Apigenin-7-O-Glucoside | Apigenin-7-O-Glucoside. CAS No. 578-74-5. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Apigenin 7-O-glucuronide | Apigenin 7-O-glucuronide. Group: Biochemicals. CAS No. 29741-09-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Apigenin-7-O-glucuronide | Apigenin-7-O-glucuronide. Group: Biochemicals. Grades: Plant Grade. CAS No. 29741-09-1. Pack Sizes: 10mg. Molecular Formula: C21H18O11, Molecular Weight: 446.36. US Biological Life Sciences. | Worldwide |
| Apigenin 7-O-methylglucuronide | Apigenin 7-O-methylglucuronide is a flavonoid glycoside isolated from Physocarpus capitatus. Synonyms: (2S,3S,4S,5R,6S)-Methyl 3,4,5-trihydroxy-6-((5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylate. Grade: 98.0%. CAS No. 53538-13-9. Molecular formula: C22H20O11. Mole weight: 460.4. |  |
| Apigenin-[d5] | Apigenin-[d5] is the labelled analogue of Apigenin, which is the main active ingredient of Chamomil extract. Chamomile is rich in flavonoid active ingredients, which has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. Synonyms: Apigenin D5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3',5'-d5]-Apigenin. Grade: ≥96%. CAS No. 263711-74-6. Molecular formula: C15H5D5O5. Mole weight: 275.27. | |
| Apigenin-d5 7-Glucuronide | Apigenin-d5 7-Glucuronide is labelled Apigenin 7-Glucuronide (A726505), a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H13D5O11, Molecular Weight: 451.39. US Biological Life Sciences. | Worldwide |
| Apigenin-d5 (Major) | The labeled aglucon of apiin and of apigenin-7-glucoside. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3,5-d5]-Apigenin. Grades: Highly Purified. CAS No. 263711-74-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Apigeninidin chloride | Apigeninidin chloride. CAS No. 1151-98-0. Product ID: ACM1151980. Molecular formula: C15H11ClO4. Mole weight: 290.7. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Apigeninidin (chloride) | Apigeninidin (chloride). Alternative Names: 3-desoxy Pelargonidin. CAS No. 1151-98-0. Purity: >98.0%. Product ID: FFC-AR-1151980. Molecular formula: C15H11ClO4. Mole weight: 290.7. IUPAC Name: 2-(4-hydroxyphenyl)chromenylium-5,7-diol chloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Apigenin impurity 1 | Apigenin impurity 1. Uses: For analytical and research use. Molecular formula: C21H18O11. Mole weight: 446.36. Catalog: APB11504. |  |
| Apigenin Liposome | Apigenin (AP) is a natural flavonoid with a variety of biological activities such as antioxidant, anti-inflammatory, anti-cancer and autoimmunity. This product is a pre-formulated liposome encapsulating Apigenin. It is only for research purposes. Group: Drug-loaded liposome. |  |
| Apigenin (Standard) | Apigenin (Standard) is the analytical standard of Apigenin. This product is intended for research and analytical applications. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4',5,7-Trihydroxyflavone(Standard); Apigenol(Standard); C.I. Natural Yellow 1 (Standard). CAS No. 520-36-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1201R. | |
| Apigetrin (Apigenin-7-O-glucoside) | Apigetrin (Apigenin-7-O-glucoside). Group: Biochemicals. Alternative Names: Apigenin 7-O-glucoside; Cosmetin. Grades: Plant Grade. CAS No. 578-74-5. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.38. US Biological Life Sciences. | Worldwide |
| AP-III-a4 | AP-III-a4 is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM); inhibit cancer cell metastasis in vivo. Synonyms: ENOblock. Grade: >98%. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.72. | |
| AP-III-a4 | AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ENOblock. CAS No. 1177827-73-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-15858. | |
| AP-III-a4 hydrochloride | AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ENOblock hydrochloride. CAS No. 2070014-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858A. | |
| Apiin | Apiin is a flavonoid glycoside-based iNOS inhibitor. Apiin inhibits the expression of inducible nitric oxide synthase in activated macrophages. Apiin exhibits anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Apigenin 7-O-apiosylglucoside; Apigenin 7-(2-O-apiosylglucoside). CAS No. 26544-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0577. | |
| Apiin | Apiin. Group: Biochemicals. Grades: Plant Grade. CAS No. 26544-34-3. Pack Sizes: 20mg. Molecular Formula: C26H28O14, Molecular Weight: 564.49. US Biological Life Sciences. | Worldwide |
| Apilimod | Apilimod is a potent and orally bioavailable inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: STA-5326; STA 5326; STA5326; N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grade: 99%. CAS No. 541550-19-0. Molecular formula: C23H26N6O2. Mole weight: 418.49. | |
| Apilimod | Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STA 5326; LAM-002A free base; AIT-101. CAS No. 541550-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14644. | |
| Apilimod mesylate | The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grade: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7. | |
| Apilimod mesylate | Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STA 5326 mesylate; LAM-002A; AIT-101 mesylate. CAS No. 870087-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644A. | |
| Apilimod (STA-5326) | Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod (STA-5326) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM. Group: Inhibitors. Alternative Names: STA-5326. CAS No. 541550-19-0. Pack Sizes: 5mg. Product ID: S6414. Formula: C23H26N6O2. Smiles: CC1=CC(=CC=C1)C=NNC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| Apimostinel | Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel; (2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grade: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60. | |
| a-Pinene oxide | a-Pinene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1686-14-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| a-Pinene oxide | a-Pinene oxide. Alternative Names: 2,3-epoxy-pinan. CAS No. 1686-14-2. Purity: 0.97. Product ID: ACM-MO-1686142. Molecular formula: C10H16O. Mole weight: 152.23 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| APIO-EE-07 | APIO-EE-07 is a dual-target inhibitor of RSK1 and MSK2. It was shown to suppress colon cancer cell growth and anchorage-independent growth. Synonyms: 5-Fluoro-3-(4-(4-nitrophenyl)-2-oxobut-3-enylidene)indolin-2-one. Grade: 98%. CAS No. 1606160-46-6. Molecular formula: C18H11FN2O4. Mole weight: 338.29. | |
| Apiogalacturonan | Apiogalacturonan is a pectin found in the walls of Lemna and Zostera marina. Apiogalacturonan, depicted as a remarkable bioactive polysaccharide deeply rooted in the plant kingdom, showcasing immense promise application in studying diverse ailments such as malignancies, diabetes and cardiovascular afflictions. Synonyms: Galacturonoapian. CAS No. 9039-3-6. | |
| Apioline | Apioline. Group: Biochemicals. Alternative Names: 4,7-Dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole; Apiole; 1-Allyl-2, 5-dimethoxy-3, 4- (methylenedioxy) benzene; 1,2-Methylenedioxy-3,6-dimethoxy-4-allylbenzene; 1-Allyl-2,5-dimethoxy-3,4-methylenedioxybenzene; 4,7-Dimethoxy-5-(2-propenyl)-1,3-benzodioxole; 5-Allyl-4,7-dimethoxy-1,3-benzodioxole; Apiol; Apioline; NSC 9070; Parsley Apiole; Parsley Camphor; Petersilienapiol. Grades: Highly Purified. CAS No. 523-80-8. Pack Sizes: 25mg. Molecular Formula: C12H14O4, Molecular Weight: 222.24. US Biological Life Sciences. | Worldwide |
| Apiopaeonoside | Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa[1]. Uses: Scientific research. Category: Natural products. CAS No. 100291-86-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2161. | |
| Apiopaeonoside | Apiopaeonoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 100291-86-9. Pack Sizes: 20mg. Molecular Formula: C20H28O12, Molecular Weight: 460.43. US Biological Life Sciences. | Worldwide |
| apiose 1-reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-apiitol:NAD+ 1-oxidoreductase. Other names in common use include D-apiose reductase, and D-apiitol reductase. Group: Enzymes. Synonyms: D-apiose reductase; D-apiitol reductase. Enzyme Commission Number: EC 1.1.1.114. CAS No. 37250-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0017; apiose 1-reductase; EC 1.1.1.114; 37250-45-6; D-apiose reductase; D-apiitol reductase. Cat No: EXWM-0017. |  |
| Apitegromab | Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SRK-015. CAS No. 2278276-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99441. | |
| Apitolisib | Apitolisib, also known as GDC-0980 and RG7422; or GNE390, is a dual PI3 kinase/mTOR inhibitor, is also an orally available agent targeting phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy; mTOR, a serine/threonine kinase downstream of PI3K, may also be activated in a PI3K-independent fashion. Synonyms: GDC-0980; GDC0980; GDC 0980; RG7422; RG-7422; RG 7422; GNE 390; GNE390; GNE-390; Apitolisib. CAS No. 1032754-93-0. Molecular formula: C23H30N8O3S. Mole weight: 498.606. | |
| Apitolisib | Apitolisib (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC50s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with a?Ki?of 17 nM for mTOR. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0980; GNE 390; RG 7422. CAS No. 1032754-93-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13246. | |
| Apium graveolens seed oil | Apium graveolens seed oil. Alternative Names: Apium graveolens l. seed oil. CAS No. 8015-90-5. Product ID: FFC-AR-8015905. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Apixaban | Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-562247-01. CAS No. 503612-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50667. | |
| Apixaban | Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases. Category: Active pharmaceutical ingredients. Synonyms: Eliquis;BMS-562247-01;BMS-562247. Grades: USMF/ASMF/CADMF/China DMF/DMF/WC/KDMF/CDE. CAS No. 503612-47-3. Product ID: API503612473. Molecular formula: C25H25N5O4. Mole weight: 459.5. EINECS: 639-684-6. SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N. Appearance: White to pale-yellow powder. Standard: In-house/CP/USP/EP/JP Facility GMP Product GMP. |  |
| Apixaban | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C25H25N5O4. CAS No. 503612-47-3. Prepack ID 70419224-100mg. Molecular Weight 459.5. See USA prepack pricing. |  |
| Apixaban | Apixaban (INN, trade name Eliquis) is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Apixaban has been available in Europe since May 2011. The drug was developed in a joint venture by Pfizer and Bristol-Myers Squibb. Uses: Factor xa inhibitors. Synonyms: BMS-562247-01; BMS 562247-01; BMS562247-01; brand name: Eliquis. Grade: 0.98. CAS No. 503612-47-3. Molecular formula: C25H25N5O4. Mole weight: 459.506. | |
| Apixaban-[13C,d3] | Apixaban-[13C,d3] is the labelled analogue of Apixaban. Apixaban is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Synonyms: Apixaban-13C,D3; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide-13C,d3; BMS 562247-01-13C,d3; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Amide-13C,d3; Eliquis-13C,d3. Grade: ≥96% by HPLC; 99% atom 13C; 99% atom D. CAS No. 1261393-15-0. Molecular formula: C24[13C]H22D3N5O4. Mole weight: 463.52. | |
| Apixaban Acid | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; Apixaban Impurity 41. CAS No. 503614-92-4. Molecular formula: C25H24N4O5. Mole weight: 460.5. | |
| Apixaban Acid-[13C,d3] | Apixaban Acid-[13C,d3] is the labelled analogue of Apixaban Acid, which is an intermediate of the synthesis of Apixaban, an inhibitor of blood coagulation factor Xa. Synonyms: Apixaban Acid-13C,D3; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid-13C,d3; Apixaban carboxylic acid-13C,d3. Grade: ≥99% by HPLC; 99% atom 13C; 99% atom D. Molecular formula: C24[13C]H21D3N4O5. Mole weight: 464.49. | |
| Apixaban Amine Amide Impurity | An impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; Apixaban Impurity 17. CAS No. 1423803-24-0. Molecular formula: C20H19N5O3. Mole weight: 377.40. | |
| Apixaban Amino Acid Impurity | It is an open ring impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: Apixaban open ring acid; Apixaban Open Chain Acid; 5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic acid. CAS No. 2206825-87-6. Molecular formula: C25H27N5O5. Mole weight: 477.51. | |
| Apixaban-d3 | Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban (HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Kis of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-562247-01-d3. CAS No. 1131996-12-7. Pack Sizes: 5 mg. Product ID: HY-50667S1. | |
| Apixaban Degradation of Impurity | Apixaban Degradation of Impurity. Uses: For analytical and research use. Alternative Names: 3-carbamoyl-1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-5-carboxylic acid. Molecular formula: C25H27N5O5. Mole weight: 477.51. Catalog: APB02354. | |
| Apixaban Dehydro Impurity | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 4,5-Dehydro Apixaban; 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide. Grade: > 95%. CAS No. 1074549-89-5. Molecular formula: C25H23N5O4. Mole weight: 457.49. | |
| Apixaban Dimer Impurity | Apixaban Dimer Impurity. Uses: For analytical and research use. Alternative Names: 6,6'-(diazene-1,2-diylbis(4,1-phenylene))bis(1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide). CAS No. 1998079-11-0. Molecular formula: C40H34N10O6. Mole weight: 750.76. Catalog: APB1998079110. | |
| Apixaban Impurity 100 | Apixaban Impurity 100. Uses: For analytical and research use. Alternative Names: N-(4-methoxyphenyl)-N-methylnitrous amide. CAS No. 940-11-4. Molecular formula: C8H10N2O2. Mole weight: 166.18. Catalog: APB940114. | |
| Apixaban Impurity 101 | Apixaban Impurity 101. Uses: For analytical and research use. Alternative Names: N-isopropyl-N-(4-methoxyphenyl)nitrous amide. Molecular formula: C10H14N2O2. Mole weight: 194.23. Catalog: APB02326. | |
| Apixaban Impurity 102 | Apixaban Impurity 102. Uses: For analytical and research use. Alternative Names: N,N-bis(4-methoxyphenyl)nitrous amide. CAS No. 6947-36-0. Molecular formula: C14H14N2O3. Mole weight: 258.27. Catalog: APB6947360. | |
| Apixaban Impurity 103 | Apixaban Impurity 103. Uses: For analytical and research use. Alternative Names: 3-chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one. CAS No. 536760-29-9. Molecular formula: C11H9ClN2O3. Mole weight: 252.65. Catalog: APB536760299. | |
| Apixaban Impurity 104 | Apixaban Impurity 104. Uses: For analytical and research use. Alternative Names: 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1642569-42-3. Molecular formula: C20H17N5O5. Mole weight: 407.38. Catalog: APB1642569423. | |
| Apixaban Impurity 105 | Apixaban Impurity 105. Uses: For analytical and research use. Alternative Names: ethyl 6-(4-(5-bromopentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate. CAS No. 881386-12-5. Molecular formula: C27H29BrN4O5. Mole weight: 568.13. Catalog: APB881386125. | |
| Apixaban Impurity 106 | Apixaban Impurity 106. Uses: For analytical and research use. Alternative Names: 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.38. Catalog: APB1704504937. | |
| Apixaban Impurity 107 | Apixaban Impurity 107. Uses: For analytical and research use. Alternative Names: 6-(4-((5-amino-5-oxopentyl)(nitroso)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. Molecular formula: C25H27N7O5. Mole weight: 505.53. Catalog: APB02325. | |
| Apixaban Impurity 108 | Apixaban Impurity 108. Uses: For analytical and research use. Alternative Names: 1-(4-ethoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. Molecular formula: C26H27N5O4. Mole weight: 473.52. Catalog: APB02324. | |
| Apixaban Impurity 109 | Apixaban Impurity 109. Uses: For analytical and research use. Alternative Names: 1-(4-methoxyphenyl)-N-methyl-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. Molecular formula: C26H27N5O4. Mole weight: 473.52. Catalog: APB02322. | |
| Apixaban Impurity 110 | Apixaban Impurity 110. Uses: For analytical and research use. Alternative Names: 1,2-bis(4-methoxyphenyl)diazene oxide. CAS No. 1562-94-3. Molecular formula: C14H14N2O3. Mole weight: 258.27. Catalog: APB1562943. | |
| Apixaban Impurity 111 | Apixaban Impurity 111. Uses: For analytical and research use. Alternative Names: 1-(4-methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide. Molecular formula: C27H28N4O4. Mole weight: 472.54. Catalog: APB02323. | |
| Apixaban Impurity 112 | Apixaban Impurity 112. Uses: For analytical and research use. Alternative Names: 1-(4-methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide. Molecular formula: C27H28N4O4. Mole weight: 472.54. Catalog: APB02320. | |
| Apixaban Impurity 13 | Apixaban Impurity 13. Uses: For analytical and research use. Molecular formula: C25H28N6O4. Mole weight: 476.54. Catalog: APB06752. | |
| Apixaban Impurity 134 | Apixaban Impurity 134. Uses: For analytical and research use. Molecular formula: C22H20N4O5. Mole weight: 420.43. Catalog: APB06756. | |
| Apixaban Impurity 135 | Apixaban Impurity 135. Uses: For analytical and research use. CAS No. 1904628-12-1. Molecular formula: C28H30N4O6. Mole weight: 518.57. Catalog: APB1904628121. | |
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