A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Aristeromycin is a nucleoside antibiotic produced by Streptomyces citricolor. It has a minimum inhibitory concentration of 5 mg/mL against Xanthomonas oryzae and Pear. Alternative Names: Cycloadenosine; (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol. CAS No. 19186-33-5. Molecular formula: C11H15N5O3. Mole weight: 265.27.
Aristeromycin
Aristeromycin, an adenosine analog, is an antibiotic and a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19186-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112639.
ARISTOLACTAM-AII
Aristolactam AII is an alkaloid compound found in the herbs of Aristolochia debilis Sieb. et Zucc. Aristolactam AII exhibits the activities of antiinflammatory and antimicrobial. Aristolactam AII also has platelet aggregation inhibitory activity. Uses: Antiinflammatory, antimicrobial. Alternative Names: 2-Hydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one; 3-Hydroxy-4-methoxy-10-aminophenanthrene-1-carboxylic acid 1,10-lactam. Grades: >98%. CAS No. 53948-07-5. Molecular formula: C16H11NO3. Mole weight: 265.3.
Aristolactam FI
Aristolactam FI is a natural alkaloid found in the roots of Piper longum, it shows platelet aggregation inhibitory activity and may be potential cancer chemotherapeutic and chemopreventive agents. Uses: Anti-cancer. Alternative Names: 1-Hydroxy-2-methoxydibenz[cd,f]indol-4(5H)-one; Piperolactam A. Grades: >95%. CAS No. 112501-42-5. Molecular formula: C16H11NO3. Mole weight: 265.3.
aristolochene synthase
The initial internal cyclization produces the monocyclic intermediate germacrene A; further cyclization and methyl transfer converts the intermediate into aristolochene. While in some species germacrene A remains as an enzyme-bound intermediate, it has been shown to be a minor product of the reaction in Penicillium roqueforti (see also EC 4.2.3.23, germacrene-A synthase). The enzyme from Penicillium roqueforti requires Mg2+. Mn2+ can partially substitute, at low concentrations. Aristolochene is the likely parent compound for a number of sesquiterpenes produced by filamentous fungi. Group: Enzymes. Synonyms: sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Enzyme Commission Number: EC 4.2.3.9. CAS No. 94185-89-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5253; aristolochene synthase; EC 4.2.3.9; 94185-89-4; sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Cat No: EXWM-5253.
Aristolochic acid
5mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C17H11NO7. CAS No. 313-67-7. Prepack ID 17348594-5mg. Molecular Weight 341.2717. See USA prepack pricing.
Aristolochic acid A
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines[1]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Aristolochic acid I; TR 1736. CAS No. 313-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0510.
Aristolochic acid A
Aristolochic acid A. Group: Biochemicals. Alternative Names: 8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochine; Aristolochia A. Grades: Highly Purified. CAS No. 313-67-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H11NO7. US Biological Life Sciences.
Worldwide
Aristolochic acid b
Aristolochic acid b. Alternative Names: ARISTOLOCHIC ACID II;ARISTOLOCHIC ACID A, 7-HYDROXY-;ARISTOLOCHIC ACID B;3,4-(methylenedioxy)-10-nitrophenanthrene-1-carboxylicacid;4-d)-1,3-dioxole-5-carboxylicacid,6-nitro-phenanthro(;6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;?3,4-(Methyle. CAS No. 475-80-9. Purity: 97%+. Product ID: ACM475809. Molecular formula: C16H9NO6. Mole weight: 311.25. IUPAC Name: 6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylicacid. Canonical SMILES: C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-]. ECNumber: 207-499-6. Alfa Chemistry - ISO 9001:32057 Certified.
Aristolochic acid B
Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aristolochic acid II. CAS No. 475-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N0511.
Aristolochic acid B
Aristolochic acid B. Group: Biochemicals. Alternative Names: 6-Nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid II; 3,4-(Methylenedioxy)-10-nitrophenanthrene-1-carboxylic acid. Grades: Highly Purified. CAS No. 475-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H9NO6. US Biological Life Sciences.
Worldwide
Aristolochic Acid B
Aristolochic acids occur in Aristolochiaceae and in butterflies feeding on these plants. One of a group of fourteen known, substituted 1-phenanthrenecarboxylic acids. Alternative Names: Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 6-nitro-; 6-Nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid II; 3,4-(Methylenedioxy)-10-nitrophenanthrene-1-carboxylic acid. Grades: >98%. CAS No. 475-80-9. Molecular formula: C16H9NO6. Mole weight: 311.25.
Aristolochic acid C
Aristolochic acid C. Group: Biochemicals. Alternative Names: 10-Hydroxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid IIIa. Grades: Highly Purified. CAS No. 4849-90-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H9NO7. US Biological Life Sciences.
Worldwide
Aristolochic acid D
Aristolochic acid D is an alkaloid with nephrotoxic and carcinogenic effects. Alternative Names: Aristolochic acid Iva; aristolochic D. Grades: 98%. CAS No. 17413-38-6. Molecular formula: C17H11NO8. Mole weight: 357.3.
Aristolochic acid D
Aristolochic acid D. Group: Biochemicals. Alternative Names: 10-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid; Aristolochic acid IVa. Grades: Highly Purified. CAS No. 17413-38-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H11NO8. US Biological Life Sciences.
Worldwide
Aristolochic acid e
Aristolochic acid e. Alternative Names: 8-Hydroxy-9-methoxy-6-nitrophenanthro[4,3-d]-1,3-dioxole-5-carboxylic Acid. CAS No. 107259-48-3. Purity: 96%. Product ID: ACM107259483. Molecular formula: C17H11NO8. Mole weight: 357.27. IUPAC Name: 8-hydroxy-9-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Aristolochic acid II
Aristolochic acid II. Group: Biochemicals. CAS No. 475-80-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Aristolochic Acid Impurity 1
Aristolochic Acid Impurity 1. Uses: For analytical and research use. CAS No. 38965-71-8. Molecular formula: C16H9NO7. Mole weight: 327.25. Catalog: APB38965718.
ARISTOLOCHICACIDSALTS
ARISTOLOCHICACIDSALTS. CAS No. 15918-62-4. Product ID: ACM15918624. Alfa Chemistry - ISO 9001:32057 Certified.
Aristololactam
The cytotoxic potency of Aristololactam I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase 3-dependent pathway. Alternative Names: aristololactam; 8-methoxy[1,3]benzodioxolo[6,5,4-cd]benzo[f]indol-5(6H)-one. Grades: >98%. CAS No. 13395-02-3. Molecular formula: C17H11NO4. Mole weight: 293.27.
Aristololactam
Aristololactam. Group: Biochemicals. Alternative Names: Aristolactam. Grades: Plant Grade. CAS No. 13395-02-3. Pack Sizes: 10mg. Molecular Formula: C17H11NO4, Molecular Weight: 293.274. US Biological Life Sciences.
Worldwide
Aristololactam BII
Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells. Uses: Anti-syncytium. Alternative Names: Cepharanone B. Grades: >97%. CAS No. 53948-09-7. Molecular formula: C17H13NO3. Mole weight: 279.3.
Aristololactam II
Aristololactam II is an aristololactam-related blue-fluorescent compound found in the callus tissue of Stephania cepharantha[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55610-00-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11562.
Aristolone
Aristolone is isolated from the herbs of Aristolochia debilis Sieb. et Zucc. Alternative Names: 2H-Cyclopropa[a]naphthalen-2-one,1,1a,4,5,6,7,7a,7b-octahydro-1,1,7,7a-tetramethyl-, (1aR,7R,7aR,7bS)-rel-; Aristol-9-en-8-one. CAS No. 6831-17-0. Molecular formula: C15H22O. Mole weight: 218.34.
Aristolone
Aristolone. Group: Biochemicals. Alternative Names: 9-Aristolen-8-one. Grades: Plant Grade. CAS No. 25274-27-5. Pack Sizes: 20mg. Molecular Formula: C15H22O, Molecular Weight: 218.335. US Biological Life Sciences.
Worldwide
Arisugacin A
Arisugacin is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259. Alternative Names: Arisugacin; (4aR,6aR,12aS,12bS)-9-(3,4-dimethoxyphenyl)-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione. Grades: >98%. Molecular formula: C28H32O8. Mole weight: 496.55.
Arisugacin B
Arisugacin B is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259. Alternative Names: (4aR,6aR,12aS,12bS)-4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione. Molecular formula: C27H30O7. Mole weight: 466.52.
Arisugacin H
Arisugacin H is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4260. Molecular formula: C29H36O9. Mole weight: 528.59.
Arizonin A1
Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin A1 has anti-Gram-positive bacteria activity. Alternative Names: 2H-Furo(3,2-b)naphtho(2,3-d)pyran-2,6,11-trione, 3,3a,5,11b-tetrahydro-8-hydroxy-7-methoxy-5-methyl-, (3aR-(3aalpha,5alpha,11balpha))-; Arizonin-A1. CAS No. 108890-87-5. Molecular formula: C17H14O7. Mole weight: 330.29.
Arizonin B1
Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin B1 has anti-Gram-positive bacteria activity. Alternative Names: Arizonin-B1; (3ar,5r,11br)-7-hydroxy-8-methoxy-5-methyl-3,3a,5,11b-tetrahydro-2h-benzo[g]furo[3,2-c]isochromene-2,6,11-trione. CAS No. 108890-89-7. Molecular formula: C17H14O7. Mole weight: 330.29.
Arjunetin
Arjunetin, isolated from Terminalia arjuna, is an insect feeding-deterrent and growth inhibitor[1]. Uses: Scientific research. Category: Natural products. CAS No. 31297-79-7. Pack Sizes: 10 mM * 1 mL in Methanol; 5 mg. Product ID: HY-N7592.
Arjungenin
Arjungenin, a pentacyclic triterpenoid compound, is a FXR agonist. Arjungenin can improve insulin sensitivity by regulating the function of fat cells. Arjungenin exhibits moderate free radical scavenging activity. Arjungenin has growth inhibitory activity against the insect Spilarctia obliqua. Arjungenin has significant antiviral activity against a series of viruses such as chikungunya Virus (CHIKV)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58880-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N4294.
Arjunic acid
Arjunic acid isolated from the stem bark of Terminalia arjuna. It shows activity against Gram-positive and Gram-negative bacteria. Uses: A strong antioxidant and a free radical scavenger. Alternative Names: 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid. Grades: 95%. CAS No. 31298-06-3. Molecular formula: C30H48O5. Mole weight: 488.7.
Arjunic acid
Arjunic acid (Arjuntriterpenic acid) (compound 13) is a triterpenoid compound isolated from Sanguisorba officinalis L[1]. Uses: Scientific research. Category: Natural products. Alternative Names: Arjuntriterpenic acid. CAS No. 31298-06-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2895.
Arjunolic acid
Arjunolic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 465-00-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C30H48O5. US Biological Life Sciences.
Worldwide
Arjunolic acid
Arjunolic acid. Alternative Names: (2α,3β,4α)-2,3,23-trihydroxy-olean-12-en-28-oic acid. CAS No. 465-00-9. Purity: >98.0%. Product ID: FFC-AR-465009. Molecular formula: C30H48O5. Mole weight: 488.7. IUPAC Name: (4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Arjunolic acid
Arjunolic acid is a natural triterpenoid isolated from the fruits of Terminalia chebula Retz, it has antioxidant properties and plays protective roles against chemically induced organ pathophysiology. Arjunolic acid can protect cardiac tissues from both extrinsic and intrinsic cell death pathways. Uses: Antioxidant. Alternative Names: 2,3,23-Trihydroxy-12-oleanen-28-oic acid. Grades: >98%. CAS No. 465-00-9. Molecular formula: C30H48O5. Mole weight: 488.7.
Arjunolic acid
Arjunolic acid is an orally active, multifunctional bioactive compound. Arjunolic acid exhibits free radical scavenging activity, as well as fungal and bacterial activities. Arjunolic acid induces apoptosis (Apoptosis) in various cancer cells. Arjunolic acid protects hepatocytes against induced oxidative stress and apoptosis by reducing reactive oxygen species and inhibiting NF-κB activation. Arjunolic acid regulates pancreatic dysfunction in type 2 diabetic rats by blocking the activation of the TLR-4/MyD88 and canonical Wnt pathways. Arjunolic acid inhibits neuroinflammation and ameliorates depressive behaviors via the SIRT1/AMPK/Notch1 signaling pathway in microglia. Arjunolic acid improves Crohn's disease-like colitis by restoring gut microbiota composition and inhibiting TLR4 signaling. Arjunolic acid suppresses osteosarcoma progression by inhibiting Wnt3a-mediated M2 polarization of macrophages. Arjunolic acid ameliorates diabetic retinopathy via the autophagy pathway regulated by AMPK/mTOR/HO-1. Arjunolic acid is applicable to research related to type 2 diabetes, organ toxicity, depression, Crohn's disease, osteosarcoma, diabetic retinopathy, and testicular dysfunction[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 465-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2896.
ARL 67156
ARL 67156 is an ecto-ATPase inhibitor/ATP analog. Alternative Names: ARL 67157; FPL 67156. CAS No. 160928-38-1. Molecular formula: C15H24Br2N5O12P3. Mole weight: 719.11.
ARL67156 trisodium
ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12?μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FPL 67156 trisodium. CAS No. 1021868-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103265.
ARL 67156 trisodium salt
ARL 67156 trisodium salt. Group: Biochemicals. Grades: Purified. CAS No. 1021868-83-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AR-M 1000390 hydrochloride
AR-M 1000390 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 209808-47-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AR-M 1896 acetate
AR-M 1896 acetate is the selective galanin GAL2 receptor agonist used as an antiepileptogenic agent. Alternative Names: H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2.CH3CO2H; L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucinamide acetic acid. Grades: ≥95%. Molecular formula: C56H85N13O16. Mole weight: 1196.35.
ARMAGNAC(ALCOHOL-FREEEXTRACT)
ARMAGNAC(ALCOHOL-FREEEXTRACT). Product ID: ACMA00009007. Alfa Chemistry - ISO 9001:32057 Certified.
Armenian hamster IgG isotype control-InVivo
Armenian hamster IgG isotype control-InVivo is ideal for use as an isotype control for Armenian hamster IgG antibodies in most in vivo and in vitro applications. Group: Antibodies. Pack Sizes: 1mg. Product ID: A2150. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Armeniaspirol A
Armeniaspirol A is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Alternative Names: Armeniaspirole A. CAS No. 1206881-47-1. Molecular formula: C18H19Cl2NO4. Mole weight: 384.25.
Armeniaspirol B
Armeniaspirol B is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Alternative Names: Armeniaspirole B. CAS No. 1206881-48-2. Molecular formula: C18H19Cl2NO4. Mole weight: 384.25.
Armeniaspirol C
Armeniaspirol C is a novel anti-Helicobacter pylori agent isolated from Streptomyces armeniacus that has been previously identified as an antibacterial agent against Gram-positive pathogens. Alternative Names: Armeniaspirole C. CAS No. 1206881-49-3. Molecular formula: C19H21Cl2NO4. Mole weight: 398.28.
Armentomycin
Armentomycin is an antibiotic produced by Streptomyces armentosus var. armentosus. Armentomycin mainly acts against gram-negative bacteria. Subcutaneous administration of 25mg/kg in mice appears toxic. Alternative Names: (S)-2-amino-4,4-dichlorobutanoic acid. Grades: >98%. CAS No. 10139-00-1. Molecular formula: C4H7Cl2NO2. Mole weight: 172.01.
Armepavine
Armepavine is isolated from Nelumbo nucifera. It exhibits anti-inflammatory and immunosuppressive effects. Alternative Names: (-)-Armepavine; Evoeuropine. Grades: >98%. CAS No. 524-20-9. Molecular formula: C19H23NO3. Mole weight: 313.4.
Armillyl orsellinate
Armillyl orsellinate is an antibiotic produced by Armillaria mellea 619, which has activity against gram-positive bacteria. Molecular formula: C23H30O6. Mole weight: 402.48.
Arminin-1a
Arminin-1a is a novel antimicrobial peptide discovered during investigations of the epithelial defense of the ancient metazoan Hydra.
Armoise oil
Armoise oil. Alternative Names: Artemisia leafes oil. CAS No. 8008-93-3. Purity: 95%. Product ID: FFC8008933. Molecular formula: CAS: 8008-93-3. Alfa Chemistry - ISO 9001:32057 Certified.
ARN 077
ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: URB913. CAS No. 1373625-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120813.
ARN14494
ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimers disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1037837-27-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115498.
ARN1468
ARN1468 (compound 5) is an orally active and potent SerpinA3n inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1381459-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150514.
ARN14974
ARN14974, a benzoxazolone carboxamide, is a potent and systemically active inhibitors of intracellular acid ceramidase (IC50=79 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1644158-57-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103592.
ARN14988
ARN14988 is a potent inhibitor of acid ceramidase (ACDase) (IC50=12.8 nM for the human enzyme)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1502027-70-4. Pack Sizes: 1 mg. Product ID: HY-124927.
ARN19702
ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 230 nM for human NAAA. ARN19702 has pain relief effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1971937-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145339.
ARN19874
ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor with an IC50 of ~34 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2190502-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118994.
ARN22089
ARN22089 is a oral active novel class of trisubstituted pyrimidine, blocks the interaction of CDC42 GTPases with specific downstream effectors. ARN22089 blocks tumor growth in BRAF mutant mouse melanoma model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2248691-29-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149464.
ARN25068
ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2649882-80-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144290.
ARN 272
ARN 272. Group: Biochemicals. Grades: Purified. CAS No. 488793-85-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ARN2966
ARN2966 is a potent, orally active and cross the blood-brain barrier amyloid precursor protein (APP) translation modulator. Uses: Scientific research. Category: Signaling pathways. CAS No. 102212-26-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18292.
ARN-3236
ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), with IC50s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-120856.
ARN-3236
ARN-3236 is an orally available and selective inhibitor of salt-inducible kinase 2 (SIK2). Study shows that ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. Alternative Names: 3-(2,4-dimethoxyphenyl)-4-(thiophen-3-yl)-1H-pyrrolo[2,3-b]pyridine; 3-(2,4-Dimethoxyphenyl)-4-(3-thienyl)-1H-pyrrolo[2,3-b]pyridine. CAS No. 1613710-01-2. Molecular formula: C19H16N2O2S. Mole weight: 336.41.
ARN726
ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 μM. ARN726 decreases alcohol self-administration in a dose-dependent manner[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628343-77-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124597.
Arnebin 1 is found in Arnebia euchroma. Alternative Names: Dmask; beta,beta-Dimethylacrylshikonin; Dimethylacrylshikonin; Isoarnebin I. Grades: > 95%. CAS No. 5162-1-6. Molecular formula: C21H22O6. Mole weight: 370.39.