A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Apolizumab is a humanized monoclonal antibody developed for the treatment of hematologic cancers. Synonyms: Hu1D10. Grade: 95%. CAS No. 267227-08-7.
apo-Milbemycin A3 oxime
apo-Milbemycin A3 oxime.
apo-Milbemycin A4 oxime
apo-Milbemycin A4 oxime.
Apomine
Apomine is an HMG-CoA reductase inhibitor that promotes myeloma cell apoptosis in vitro and is involved in myeloma regulation in vivo. Synonyms: Phosphonic acid, P,P'-[2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethylidene]bis-, P,P,P',P'-tetrakis(1-methylethyl) ester; Phosphonic acid, [2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethylidene]bis-, tetrakis(1-methylethyl) ester; SKF 99085; SR 45023A; SR 9223i; Tetraisopropyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl-1,1-diphosphonate. Grade: 95%. CAS No. 126411-13-0. Molecular formula: C28H52O7P2. Mole weight: 562.66.
Apomorphine
Apomorphine ((-)-Apomorphine) is a potent dopamine receptor agonist. Apomorphine also inhibit MAO-A and MAO-B. Apomorphine exerts neuroprotective effect and can relax rat corpus cavernosum. Apomorphine can inhibit ROS production, DNA fragmentation and inibit JNK and ERK1/2 phosphorylation. Apomorphine can enhance degradation of intracellular Aβ40 and Aβ42, reduces tau protein levels and inhibit MMP-9 expression. Apomorphine is a highly potent radical scavenger and iron chelator. Apomorphine can be used for the researches of dementia, parkinson's disease, alzheimer disease, breast carcinoma, and erectile dysfunction[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Apomorphine. CAS No. 58-00-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-12723.
Apomorphine hydrochloride EP impurity C
Apomorphine hydrochloride EP impurity C. Uses: For analytical and research use. Molecular formula: C34H34N2O4. Mole weight: 534.66. Catalog: APB10171.
Aponicin-1CDYa
Aponicin-1CDYa was found in Rana dybowskii. It has antibacterial activity.
Apoptolidin
Apoptolidin is an apoptosis inducer produced by Nocardiopsis sp. Apoptolidin can induce apoptosis of metastatic cells, but has no effect on normal cells. Synonyms: (1R)-O-2,6-Dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→8)-3,5,7-trideoxy-1-C-[(2S,4S,5S,8E,10E,12R,13R,14E,16E,18E)-12-[(6-deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-5-hydroxy-4-methoxy-9,13,15,17,19-pentamethyl-20-oxooxacycloeicosa-8,10,14,16,18-pentaen-2-yl]-3,5-dimethyl-9-O-methyl-L-glycero-α-D-galacto-2-nonulopyranose; Apoptolidin A; FU 40A. Grade: ≥95%. CAS No. 194874-06-1. Molecular formula: C58H96O21. Mole weight: 1129.37.
Apoptolidin
Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene at an IC50 = 11 ng/ml. It is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action. Group: Biochemicals. Grades: Highly Purified. CAS No. 194874-06-1. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Apoptosis Activator 2
Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. It increases procaspase-9 processing and subsequent caspase-3 activation. It induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM). Synonyms: Apoptosis Activator 2; AAII; N-(3,4-dichlorobenzyl) Isatin. MDK83190; MDK-83190; MDK 83190. CAS No. 79183-19-0. Molecular formula: C15H9Cl2NO2. Mole weight: 306.142.
Apoptosis Activator 2
Apoptosis Activator 2. Group: Biochemicals. Grades: Purified. CAS No. 79183-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Apoptosis Compound Library
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; - Targets include Bcl-2, Caspase, p53, TNF-alpha, and surviving, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9000. Categories: Apoptosis Compounds Libraries.
Apoptosis Inducing siRNA (5 nmol)
Apoptosis Inducing siRNA. Small interfering RNA (siRNA) is 21-25 bp in length, double-stranded small RNA molecules regulating gene expression by degrading mRNA after transcription and preventing translation. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 4062.
Nevada, Texas, USA
Apoptotic agent-3
Apoptotic agent-3 (compound 15f) promotes apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway and activation of the Caspase 3 pathway. Apoptotic agent-3 exhibits anti-proliferative activities and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2482310-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147929.
Apoptozole
Apoptozole, also known as Apoptosis Activator VII, is an apoptosis-inducing small molecule that inhibits the ATPase activity of heat shock cognate 70 (Hsc70) and Hsp70 (Kd = 210 and 140 nM, respectively). Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). Synonyms: 4-((2-(3,5-bis(trifluoromethyl)phenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl)methyl)benzamide; Apoptozole; Apoptosis Activator VII. CAS No. 1054543-47-3. Molecular formula: C33H25F6N3O3. Mole weight: 625.57.
Aposcopolamine
A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 535-26-2. Pack Sizes: 10mg. US Biological Life Sciences.
Aposcopolamine is an alkaloid that can be isolated from Datura ferox. Aposcopolamin can closely binds with ACHE, ADRA2A and CHRM2. Aposcopolamine can be used for the research of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 535-26-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8728.
Aposcopolamine, Hydrochloride Salt
A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
apo-Selamectin aglycone
apo-Selamectin aglycone.
Apostatin-1
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Apt-1. CAS No. 2559703-06-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134050.
Apostatin-1
Apostatin-1 is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Synonyms: Apt-1. CAS No. 2559703-06-7. Molecular formula: C19H27N3OS. Mole weight: 345.50.
apo-Transferrin human
100mg Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 11096-37-0. Prepack ID 18479560-100mg. See USA prepack pricing.
Apovincaminic acid
Apovincaminic acid. Group: Biochemicals. Alternative Names: (13aS,13bS)-13a-Ethyl-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid; Apovincamin-22-oic acid; (3a,16a)-Eburnamenine-14-carboxylic acid. Grades: Highly Purified. CAS No. 27773-65-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H22N2O2. US Biological Life Sciences.
Worldwide
Apovinicaminic acid hydrochloride
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,13a,13b-hexahydro-, hydrochloride (1:1), (13aS,13bS)-; (13aS,13bS)-13a-Ethyl-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid hydrochloride; Apovincamin-22-oic acid hydrochloride; (+)-Apovincaminic acid hydrochloride; (+)-cis-Apovincaminic acid hydrochloride; (3α,16α)-Eburnamenine-14-carboxylic acid hydrochloride; cis-Apovincaminic acid hydrochloride; Apovincaminic acid hydrochloride. CAS No. 72296-47-0. Molecular formula: C20H22N2O2.HCl. Mole weight: 358.86.
APP-018
APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-4F. CAS No. 452782-06-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P6365B.
AppCp
AppCp is a formidable small molecule inhibitor, intelligently studying the enigma of inflammation-related maladies. Its astute focus gravitates towards captivating the capacious CpG oligodeoxynucleotide receptor, thereby orchestrating an exquisite modulation of the immune rejoinder. Synonyms: (AMPPCP); Adenosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C11H18N5O12P3 (free acid). Mole weight: 505.21 (free acid).
Apple Cider Vinegar Extract
Apple Cider Vinegar Extract. Applications: Used for health care products, dietary supplements, weight loss. Group: Others. Synonyms: Apple Cider Vinegar Extract; Malus Pumila Mill. Purity: 5%, 10% Organic Acid By TITRATION. Appearance: White to light yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Malus Pumila Mill. Apple Cider Vinegar Extract; Malus Pumila Mill.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-100.
Apple Extract
Standardized apple (Pyrus malus) fruit extract from organic cultivation. Product ID: CI-SC-0024. Alfa Chemistry - ISO 9001:32057 Certified.
Apple Extract (Ratio)
Apple Extract (Ratio). Group: Others. Purity: 4:1~20:1. Apple Extract (Ratio). Cat No: EXTW-026.
Apple oil
Apple oil. Alternative Names: Pyrus malus domestica. CAS No. 883111-87-3. Product ID: FFC-AR-883111873. Alfa Chemistry - ISO 9001:32057 Certified.
Apple P.E. 90% Phloridzin
Apple P.E. 90% Phloridzin.
CA, FL & NJ
Apple Pectin Powder 55% Fiber
Apple Pectin Powder 55% Fiber.
CA, FL & NJ
Apple Powder
Apple powder is made of apple as raw material and processed by spray drying technology. Product ID: CDF4-0225. Category: Flavour. Product Keywords: Flavor Enhancers; Apple Powder; CDF4-0225; Flavour;. Grade: Food Grade. Color: White powder. Physical State: powder. Storage: Room Temperature. Applications: Widely used in solid drinks, tablet candy, meal replacement powder.
Apple Powder
Apple juice powder is made from fresh apple (Malus Domestica), adopt the advanced spray drying technology. Apple juice powder contain a lot of vitamins, minerals and rich in dietary fiber, especially pectin and other ingredients. Apple fruit powder also has lose weight, detoxification, whitening effect. Group: Others. Apple Powder; Malus domestica. Cat No: EXTC-081.
AppNH2
AppNH2 is indispensable in research of combating ailments including cancer, diabetes is and autoimmune disorders. This revolutionary creation assuming the role of both a mighty inhibitor and a formidable activator, skillfully honing in on crucial proteins and enzymes entangled in the labyrinthine pathways of pathological advancement. Profoundly effective is appNH2 harnesses its exceptional chemical attributes to govern intricate cellular dynamics, thereby fostering optimal physiological harmony. Synonyms: (AMPPN); Adenosine-5'-(β-amido)diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N6O9P2 (free acid). Mole weight: 426.21 (free acid).
AppNHp
AppNHp is a key recompound used in the biomedical industry for the research of nucleotide analogs and phosphorylation reactions. It plays a crucial role in the development of antiviral drugs, such as AppNHp-based inhibitors for HIV and hepatitis C virus. Synonyms: (AMPPNP); Adenosine-5'-[(β,γ)-imido]triphosphate, Tetralithium salt; AMPPNHP. Grade: ≥ 95% by HPLC. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.19 (free acid).
Approved Drug Library
A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), etc; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, GPCR/G protein, Neuroscience, Membrane Transporter/Ion Channel, Microbiology & Virology, Immunology/Inflammation, Tyrosine Kinase/Adaptors, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1000. Categories: Approved Drug Libraries.
APPROVED Glycyltyrosine
APPROVED Glycyltyrosine is a dipeptide containing glycine and L-tyrosine. CAS No. 39630-46-1. Product ID: PAP-0008. Molecular formula: C11H16N2O5. Category: Amino acid. Product Keywords: Amino Acid Series; APPROVED Glycyltyrosine; PAP-0008; Amino acid; C11H16N2O5; 39630-46-1. Standard: GMP. Color: White to Off-White. Physical State: Solid. Solubility: DMSO (Slightly), Water (Slightly). Applications: APPROVED Glycyltyrosine is a drug that belongs to the class of drugs called psychostimulants. It is a non-amphetamine stimulant and does not produce amphetamine-like effects, such as euphoria or dependence. Product Description: APPROVED Glycyltyrosine is a drug that belongs to the class of drugs called psychostimulants. It is a non-amphetamine stimulant and does not produce amphetamine-like effects, such as euphoria or dependence.
APR-246
APR-246 is a quinuclidinone derivative that targets the Wrap53 gene with potential antineoplastic activity. This agent may work synergistically with other antineoplastic agents. The Wrap53 transcript, a natural p53 antisense transcript, regulates endogenous p53 mRNA levels and additional induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Synonyms: PRIMA-1MET; Prima 1MET; Eprenetapopt; 2-(Hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one. Grade: 98%. CAS No. 5291-32-7. Molecular formula: C10H17NO3. Mole weight: 199.25.
Apraclonidine
Apraclonidine is a clonidine derivative with relatively selective alpha-2-adrenergic agonistic activity. It is an α2 adrenergic receptor agonist and a weak α1 adrenergic receptor agonist. It enhances aqueous humor uveoscleral outflow and decreases aqueous production by vasoconstriction. It is a sympathomimetic used in glaucoma therapy. It was developed by Alcon and has been listed. Uses: Apraclonidine is a sympathomimetic used in glaucoma therapy. Synonyms: 2-((4-Amino-2,6-dichlorophenyl)imino)imidazolidine; 2,6-Dichloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine; Iopidine; 4-Aminoclonidine; Apraclonidina; Apraclonidinum; P-aminoclonidine. Grade: 98%. CAS No. 66711-21-5. Molecular formula: C9H10Cl2N4. Mole weight: 245.11.
Apraclonidine hydrochloride
Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALO 2145. CAS No. 73218-79-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-12720A.
Apraclonidine hydrochloride
Apraclonidine is an α2-adrenergic receptor (α2-AR) agonist and structural analog of clonidine. It is used for the treatment of post-surgical elevated intraocular pressure. It inhibits noradrenaline-stimulated contraction in guinea pig ileum with EC50s of 7.59 nM and rabbit vas deferens with EC50s of 6.76 nM. Uses: Adrenergic alpha-2 receptor agonists. Synonyms: ALO 2145; 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine hydrochloride; Iopidine; p-Aminoclonidine monohydrochloride. Grade: ≥98%. CAS No. 73218-79-8. Molecular formula: C9H10Cl2N4·HCl. Mole weight: 281.6.
Apraclonidine Hydrochloride
α-Adrenergic agonist; structural analog of clonidine. Used for treatment of post-surgical elevated intraocular pressure. Group: Biochemicals. Alternative Names: 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine Hydrochloride; Iopidine; p-Aminoclonidine Monohydrochloride; AL 02145; ALO 2145. Grades: Highly Purified. CAS No. 73218-79-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C?H??Cl?N?, Molecular Weight: 281.57. US Biological Life Sciences.
Worldwide
Apraclonidine Hydrochloride
Apraclonidine Hydrochloride is a synthetic alpha-2 adrenergic agonist with high selectivity for the alpha-2 receptor subtype, used primarily in ophthalmology for the management of glaucoma and ocular hypertension. Its chemical structure is a clonidine derivative with a para-amino group that reduces its ability to cross the blood-brain barrier, minimizing central nervous system side effects compared to non-selective alpha-2 agonists. Applications: Apraclonidine hydrochloride is indicated for the short-term adjunctive treatment of chronic glaucoma and ocular hypertension in patients who are inadequately controlled by beta-blocker monotherapy. Category: Active pharmaceutical ingredients. Synonyms: 2-(4-amino-2,6-dichlorophenylimino)imidazolidinehydrochloride;2,6-dichloro-n(sup1)-(2-imidazolidinylidene)-1,4-benzenediaminehydrochlorid. CAS No. 73218-79-8. Product ID: API73218798. Molecular formula: C9H11Cl3N4. Mole weight: 281.6. InChIKey: OTQYGBJVDRBCHC-UHFFFAOYSA-N. Appearance: White solid.
Apraglutide
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FE 203799. CAS No. 1295353-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1714.
Apraglutide
Apraglutide is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799; His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2. Grade: ≥95%. CAS No. 1295353-98-8. Molecular formula: C172H263N43O52. Mole weight: 3765.25.
Apraglutide TFA
Apraglutide TFA is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799 (TFA); His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2.TFA. Grade: >98%. Molecular formula: C172H263N43O52.C2HF3O2. Mole weight: 3879.27.
Apramycin
Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nebramycin II. CAS No. 37321-09-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-17558.
Apramycin
Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Synonyms: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine; Ambylan; Apralan; Apralan 200 Injection; Apralin; EL 857; EL 857/820. Grade: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58.
Apramycin sulfate
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nebramycin II sulfate. CAS No. 65710-07-8. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-B1329.
Apramycin Sulfate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H41N5O11 ·H2SO4. CAS No. 65710-07-8. Prepack ID 51745110-5g. Molecular Weight 637.66. See USA prepack pricing.
Apramycin Sulfate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H41N5O11 ·H2SO4. CAS No. 65710-07-8. Prepack ID 51745110-1g. Molecular Weight 637.66. See USA prepack pricing.
Apramycin Sulfate
Apramycin Sulfate. CAS No. 65710-07-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Apramycin Sulfate
Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Synonyms: FEMA 2131; FEMA2131; FEMA-2131; D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (1:x); D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (salt); O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine sulfate; Nebramycin factor 2 sulfate. Grade: >98%. CAS No. 65710-07-8. Molecular formula: C21H41N5O11.xH2O4S. Mole weight: 539.58 (free base).
Apramycin Sulfate, Free Base
Broad spectrum aminocyclitol antibiotic and component of the Nebramycin complex, produced by a strain of Streptomyces tenebrarius. Antibacterial. Group: Biochemicals. Alternative Names: Nebramycin II; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(18)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(14)-2-deoxy-D-streptamineSulfate. Grades: Highly Purified. CAS No. 65710-07-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
Apramycin sulfate (Standard)
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nebramycin II sulfate (Standard). CAS No. 65710-07-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1329R.
Apramycin Sulphate
Apramycin Sulphate, a potent aminoglycoside antibiotic, exhibits efficacy in combating bacterial infections in animals caused by an array of Gram-negative bacteria, with a notable specificity for Enterobacteriaceae. Its mechanism of action involves hindering protein synthesis within bacterial cells, rendering it a pivotal asset in the realm of veterinary medicine. Synonyms: D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (1:1); Apramycin sulfate; Apramycin sulfate salt; Nebramycin II sulfate; Nebramycin factor 2 sulfate; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine sulfate. CAS No. 410097-64-2. Molecular formula: C21H43N5O15S. Mole weight: 637.66.
Apratastat
Apratastat (TMI-005) is an orally active, non-selective and reversible TACE/MMPs inhibitor, can inhibit inhibit the release of TNF-α. Apratastat has the potential to overcome radiotherapy-resistance in non-small cell lung cancer (NSCLC)[1][2]. Apratastat is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TMI-005. CAS No. 287405-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-119307.
Apremilast
Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Category: Active pharmaceutical ingredients. CAS No. 608141-41-9. Product ID: API608141419. Molecular formula: C22H24N2O7S. Mole weight: 460.5.
Apremilast
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Synonyms: (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004. Grade: >98%. CAS No. 608141-41-9. Molecular formula: C22H24N2O7S. Mole weight: 460.50.
Apremilast
Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-10004. CAS No. 608141-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12085.
Apremilast-[d5]
Apremilast-[d5] is the labelled analogue of Apremilast. Apremilast is a selective inhibitor of phosphodiesterase 4 (PDE4) used as a drug for psoriasis and psoriatic arthritis. Synonyms: Apremilast D5; (S)-2-[1-(3-Ethoxy-d5-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-d5-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; Apremilast-d5. Grade: >95%. CAS No. 1258597-47-5. Molecular formula: C22H19D5N2O7S. Mole weight: 465.53.
Apremilast Dimer
Apremilast Dimer is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(2'-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,1',3,3'-tetraoxo-[2,4'-biisoindolin]-4-yl)acetamide. CAS No. 1802246-60-1. Molecular formula: C30H27N3O9S. Mole weight: 605.6.
Apremilast Impurity 11
Apremilast Impurity 11. Uses: For analytical and research use. CAS No. 253168-83-1. Molecular formula: C20H22N2O6S. Mole weight: 418.46. Catalog: APB253168831.
Apremilast Impurity 18
Apremilast Impurity 18. Uses: For analytical and research use. CAS No. 1407140-51-5. Molecular formula: C20H32N2O6S. Mole weight: 428.54. Catalog: APB1407140515.
Apremilast Impurity 18
Apremilast Impurity 18. Uses: For analytical and research use. Alternative Names: N-(2-(1-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. Molecular formula: C21H22N2O7S. Mole weight: 446.47. Catalog: APB02691.
Apremilast Impurity 19
Apremilast Impurity 19. Uses: For analytical and research use. Alternative Names: N-(2-(1-(4-ethoxy-3-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. Molecular formula: C22H24N2O7S. Mole weight: 460.5. Catalog: APB02689.
Apremilast Impurity 2
A metabolite of Apremilast. Synonyms: (R)-Apremilast; N-[2-[(1R)?-1-(3-Ethoxy-4-methoxyphenyl)?-2-(methylsulfonyl)?ethyl]?-2,?3-dihydro-1,?3-dioxo-1H-isoindol-4-yl]?-acetamide. Grade: > 95%. CAS No. 608141-44-2. Molecular formula: C22H24N2O7S. Mole weight: 460.51.
Apremilast Impurity 20
Apremilast Impurity 20. Uses: For analytical and research use. CAS No. 2169153-70-0. Molecular formula: C10H15NO4S. Mole weight: 245.29. Catalog: APB2169153700.