A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
It is produced by the strain of Streptomyces galilaeus. Auramycin has the ability of anti gram-positive bacteria and tumor, with the LD50 100mg/kg (Mouse, abdominal cavity). Alternative Names: auramycin B. CAS No. 78173-91-8. Molecular formula: C41H49NO15. Mole weight: 795.83.
Auranofin
Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2?μM for monkey kidney Vero E6 cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-39162. CAS No. 34031-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1123.
Auranofin
Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Alternative Names: SKF-39162; SKF-D-39162; SKF 39162; SKF D 39162; SKFD-39162; SKFD39162; Ridaura; NSC 321521, Ridauragold thiol; Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-; [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold; Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate; Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-; β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex; [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold; Aktil; Crisinor; Crisofin Gold Salt; Ridauran; SKF 39162D. Grades: ≥98%. CAS No. 34031-32-8. Molecular formula: C20H34AuO9PS. Mole weight: 678.49.
Auranofin 99+%
Auranofin 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences.
Aurantiamide is a non-covalent, orally active, blood-brain-permeable GRPR selective antagonist with anti-inflammatory and neuroprotective effects. Aurantiamide reduces inflammation and oxidative stress in renal tissue by inhibiting GRPR-mediated renal necrosis pathways (such as RIPK3/MLKL signaling) and NF-κB inflammatory pathways, exerting anti-acute kidney injury and endothelial function activities. Aurantiamide also inhibits the M1 polarization of microglia and inhibits NLRP3 activation, thereby improving AD mouse models. Aurantiamide has in vivo inhibitory efficacy in acute kidney injury models such as ischemia/reperfusion, sepsis, and hypertension models[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58115-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N2909.
Aurantiamide acetate
Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Asperglaucide. CAS No. 56121-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2905.
Aurantimycin A
Aurantimycin A is an antibiotic isolated from Streptomyces aurantiacus IMET 43917. Aurantimycin A has activity against Gram-positive bacteria and inhibits cell adhesion. Alternative Names: Aurantimycin; NSC-777195; D-Alanine, (3S)-3-hydroxy-N-[(2R)-2-hydroxy-1-oxo-2-[(2S,5S,6S)-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-O-methyl-L-serylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-, (6→13)-lactone. Grades: ≥95%. CAS No. 162478-50-4. Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycinn A
Aurantimycinn A is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn A has strong anti-gram positive bacterial activity, with MIC 0.007-0.08μg/mL, which can be tolerated by mice 1mg/kg (intravenous), 250mg/kg (oral). Molecular formula: C38H64N8O14. Mole weight: 856.96.
Aurantimycinn B
Aurantimycinn B is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn B has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H62N8O14. Mole weight: 854.94.
Aurantimycinn C
Aurantimycinn C is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn C has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H60N8O14. Mole weight: 852.93.
Aurantiogliocladin
It is produced by the strain of Gliocladium roseum. Aurantiogliocladin has weak activity of anti-gram positive bacteria, negative bacteria and fungal. Alternative Names: 2,3-DIMETHOXY-5,6-DIMETHYL-2,5-CYCLOHEXADIENE-1,4-DIONE; 2,3-DIMETHOXY-5,6-DIMETHYL-P-BENZOQUINONE; AURANTIOGLIOCLADIN; 2,3-Dimethoxy-5,6-dimethyl-1,4-benzoquinone. Grades: 95%. CAS No. 483-54-5. Molecular formula: C10H12O4. Mole weight: 196.20.
Aurantiol
Aurantiol. CAS No. 89-43-0. Kosher: Y. VIGON Item # 500018. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers.
America & Internationally
Aurantioobtusin
Aurantioobtusin. Group: Biochemicals. Alternative Names: 1,3,7-Trihydroxy-2,8-dimethoxy-6-methyl-9,10-anthracenedione. Grades: Highly Purified. CAS No. 67979-25-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C17H14O7. US Biological Life Sciences.
Worldwide
Aurantio-obtusin
Aurantio-obtusin. Group: Biochemicals. Grades: Plant Grade. CAS No. 67979-25-3. Pack Sizes: 20mg. Molecular Formula: C17H14O7, Molecular Weight: 330.29. US Biological Life Sciences.
Worldwide
AurAP14
AurAP14 is an Aurora A PROTAC degrader (DC50 = 120 nM). AurAP14 shows significant inhibitory activity against various tumor cell lines, with IC50s of 0.294 μM in A549 cells and 0.534 μM in MCF-7 cells. AurAP14 induces apoptosis and arrests A549 cells in the S and G2/M phases. AurAP14 demonstrates anti-tumor efficacy in nude mouse xenograft models of A549 and A549/PTR. AurAP14can be used in the research on the treatment of Aurora A-overexpressing NSCLC. (Pink: Aurora A ligand (HY-10971), Blue: E3 ligase Ligand (HY-W437598), Black: Linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3106831-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-178472.
Auraptene
Auraptene. Group: Biochemicals. Alternative Names: 7-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one; 7-(Geranyloxy)-coumarin; 7-[(3,7-Dimethyl-2,6-octadienyl)oxy]-coumarin; (E)-7-Geranoxycoumarin; 7-Geranyloxycoumarin; Aurapten; Aurapten (C19H22O3); Auraptene. Grades: Highly Purified. CAS No. 495-02-3. Pack Sizes: 100mg. Molecular Formula: C19H22O3, Molecular Weight: 298.38. US Biological Life Sciences.
Worldwide
Auraptenol
Auraptenol is a natural coumarin found in the fruits of Citrus aurantium. It has antifibrotic activity and the anti-hyperalgesic action which may be as a novel analgesic for the management of neuropathic pain. Uses: Antifibrotic, anti-hyperalgesic. Alternative Names: (+)-8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-1-benzopyran-2-one. Grades: >98%. CAS No. 1221-43-8. Molecular formula: C15H16O4. Mole weight: 260.3.
Aurein-1.1 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Alternative Names: Gly-Leu-Phe-Asp-Ile-Ile-Lys-Lys-Ile-Ala-Glu-Ser-Ile-NH2; Aurein 1.1. Grades: ≥97%. Molecular formula: C68H116N16O18. Mole weight: 1445.77.
Aurein-1.2
Aurein-1.2 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Alternative Names: H-Gly-Leu-Phe-Asp-Ile-Ile-Lys-Lys-Ile-Ala-Glu-Ser-Phe-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-isoleucyl-L-alanyl-L-alpha-glutamyl-L-seryl-L-phenylalaninamide; Aurein 1.2. Grades: ≥96%. Molecular formula: C71H114N16O18. Mole weight: 1479.78.
Aurein-2.1
Aurein-2.1 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 2.1; H-Gly-Leu-Leu-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Phe-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-phenylalanyl-glycyl-L-seryl-L-leucinamide. Grades: ≥96%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.2
Aurein-2.2 is an amphipathic alpha-helical antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Leu-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-leucyl-glycyl-L-seryl-L-leucinamide; Aurein 2.2. Grades: >97%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.3
Aurein-2.3 is an antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Ile-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-isoleucyl-glycyl-L-seryl-L-leucinamide; Aurein 2.3. Grades: ≥97%. Molecular formula: C76H131N19O19. Mole weight: 1615.00.
Aurein-2.4
Aurein-2.4 is an amphipathic alpha-helical antimicrobial peptide and nNOS inhibitor produced by Litoria aurea (Ranoidea aurea, Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Thr-Ile-Ala-Gly-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-threonyl-L-isoleucyl-L-alanyl-glycyl-L-leucinamide; Aurein 2.4. Grades: ≥96%. Molecular formula: C77H133N19O19. Mole weight: 1629.03.
Aurein-2.5
Aurein-2.5 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 2.5; H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Phe-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valyl-glycyl-L-alanyl-L-phenylalanyl-glycyl-L-seryl-L-leucinamide. Grades: >98%. Molecular formula: C79H129N19O19. Mole weight: 1649.02.
Aurein-2.6
Aurein-2.6 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 2.6; H-Gly-Leu-Phe-Asp-Ile-Ala-Lys-Lys-Val-Ile-Gly-Val-Ile-Gly-Ser-Leu-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-alanyl-L-lysyl-L-lysyl-L-valyl-L-isoleucyl-glycyl-L-valyl-L-isoleucyl-glycyl-L-seryl-L-leucinamide. Grades: ≥97%. Molecular formula: C77H133N19O19. Mole weight: 1629.03.
Aurein-3.1
Aurein-3.1 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 3.1; Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Ala-Gly-Ser-Ile-NH2. Grades: ≥97%. Molecular formula: C81H136N22O20. Mole weight: 1738.11.
Aurein-3.2
Aurein-3.2 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 3.2; H-Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Ala-Ser-Ser-Ile-NH2; glycyl-L-leucyl-L-phenylalanyl-L-alpha-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-isoleucyl-L-alanyl-glycyl-L-histidyl-L-isoleucyl-L-alanyl-L-seryl-L-seryl-L-isoleucinamide. Grades: ≥96%. Molecular formula: C82H138N22O21. Mole weight: 1768.14.
Aurein-3.3
Aurein-3.3 is an antimicrobial peptide produced by Litoria raniformis (Litoria aurea, Southern bell frog). It has antibacterial and anticancer activity. Alternative Names: Aurein 3.3; Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Ile-Ala-Gly-His-Ile-Val-Ser-Ser-Ile-NH2. Grades: ≥96%. Molecular formula: C84H142N22O21. Mole weight: 1796.19.
Aurein-5.2
Aurein-5.2 is an antimicrobial peptide produced by Litoria raniformis (Southern bell frog) and Litoria aurea (Green and golden bell frog). It has antibacterial activity. Alternative Names: Aurein 5.2; Gly-Leu-Met-Ser-Ser-Ile-Gly-Lys-Ala-Leu-Gly-Gly-Leu-Ile-Val-Asp-Val-Leu-Lys-Pro-Lys-Thr-Pro-Ala-Ser-OH. Grades: ≥96%. Molecular formula: C110H194N28O32S. Mole weight: 2452.98.
Aurelin
Aurelin is an antimicrobial peptide produced by Aurelia aurita (Moon jellyfish). It has antibacterial activity against the Gram-positive bacterium L.monocytogenes and the Gram-negative bacterium E.coli. Alternative Names: Ala-Ala-Cys-Ser-Asp-Arg-Ala-His-Gly-His-Ile-Cys-Glu-Ser-Phe-Lys-Ser-Phe-Cys-Lys-Asp-Ser-Gly-Arg-Asn-Gly-Val-Lys-Leu-Arg-Ala-Asn-Cys-Lys-Lys-Thr-Cys-Gly-Leu-Cys (Disulfide bridge: Cys3-Cys33, Cys12-Cys37, Cys19-Cys40). Grades: >98%. Molecular formula: C176H284N60O54S6. Mole weight: 4296.93.
Aureobasidin A
Aureobasidin A is a cyclic depsipeptide antibiotic isolated from the filamentous fungus Aureobasidium pullulans R106. It is an antifungal agent that inhibits phosphorylceramide synthase. Alternative Names: Basifungin. CAS No. 127785-64-2. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Aureobasidin A
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Basifungin. CAS No. 127785-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1975.
Aureobasidine A
Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42.
Aureocin A53
Aureocin A53 is an antimicrobial peptide produced by Staphylococcus aureus A53. It has antibacterial activity against Gram-positive bacteria: Listeria monocytogenes, Staphylococcus simulans (MIC=100 nM), Staphylococcus aureus (MRSA), Streptococcus agalactiae, Micrococcus luteus (MIC=0.15 nM). Alternative Names: N-formylmethionine-Ser-Trp-Leu-Asn-Phe-Leu-Lys-Tyr-Ile-Ala-Lys-Tyr-Gly-Lys-Lys-Ala-Val-Ser-Ala-Ala-Trp-Lys-Tyr-Lys-Gly-Lys-Val-Leu-Glu-Trp-Leu-Asn-Val-Gly-Pro-Thr-Leu-Glu-Trp-Val-Trp-Gln-Lys-Leu-Lys-Lys-Ile-Ala-Gly-Leu; aucA. Grades: >85%. Molecular formula: C292H447N69O66S. Mole weight: 6012.27.
aureolysin
A metalloenzyme from S. aureus earlier confused with staphylokinase (a non-enzymic activator of plasminogen). Group: Enzymes. Synonyms: Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Enzyme Commission Number: EC 3.4.24.29. CAS No. 39335-13-2. Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4310; aureolysin; EC 3.4.24.29; 39335-13-2; Staphylococcus aureus neutral proteinase; Staphylococcus aureus neutral protease. Cat No: EXWM-4310.
Aureoquinone
Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Alternative Names: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20.
Aureothin
Aureothin is produced by the strain of Streptomyces thioluteus 4-A-1 and Streptomyces sp. 58. An unusual pyranone metabolite; has broad biological actions including antitumour, antimicrobial and insecticidal activities; a potent inhibitor of helicobacter pylori. Alternative Names: Distacin; Mycolutein. Grades: >95% by HPLC. CAS No. 2825-00-5. Molecular formula: C29H26ClF3N2O6. Mole weight: 591.
Aureothricin
Aureothricin. Group: Biochemicals. Alternative Names: Propionylpyrrothione. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H10N2O2S2. US Biological Life Sciences.
Worldwide
Aureothricin
Aureothricin is produced by the strain of Streptomyces celluloflavus. It was active against gram-positive bacteria, negative bacteria and Mycobacterium, and intraperitoneal injection could inhibit the increase of ascites in transplanted mice with Aldrin ascites carcinoma. Alternative Names: Propionylpyrrothione; Farcinin. Grades: >98% by HPLC. CAS No. 574-95-8. Molecular formula: C9H10N2O2S2. Mole weight: 242.32.
Aureusidin
Aureusidin. Group: Biochemicals. Alternative Names: (2Z) -2-[ (3, 4-dihydroxyphenyl) methylene]-4, 6-dihydroxy-3 (2H) -benzofuranone; Cernuin. Grades: Highly Purified. CAS No. 38216-54-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C15H10O6. US Biological Life Sciences.
Worldwide
aureusidin synthase
A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4'-O-β-D-glucoside in vivo. Group: Enzymes. Synonyms: AmAS1. Enzyme Commission Number: EC 1.21.3.6. CAS No. 320784-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1253; aureusidin synthase; EC 1.21.3.6; 320784-48-3; AmAS1. Cat No: EXWM-1253.
Aureusimine B
It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Alternative Names: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grades: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29.
Auric sodium Chloride
Auric sodium Chloride. Alternative Names: Sodium tetrachloroaurate. CAS No. 15189-51-2. Purity: Au 48.0%. Product ID: ACM15189512. Molecular formula: NaAuCl4ยท2H2O. Mole weight: 397.8. Alfa Chemistry - ISO 9001:32057 Certified.
Auriculasin
Auriculasin is an anticancer agent that inhibits VEGFR2, PI3K/AKT/mTOR, MAPK. Auriculasin can inhibit cell proliferation, induce cell apoptosis, and inhibit angiogenesis, and promotes mitochondrial oxidative stress and ferroptosis. Auriculasin is also active at the cannabinoid receptor CB1 with an IC50 of 8.92 μM. Auriculasin can be used in cancer research, especially related diseases such as prostate cancer and non-small cell lung cancer, as well as research on the development of anti-angiogenic drugs[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60297-37-2. Pack Sizes: 1 mg. Product ID: HY-N2911.
Auriculasin
Auriculasin is a flavonoid derivative isolated from the herbs of Derris robusta. Alternative Names: Cudraisoflavone A. Grades: 96%. CAS No. 60297-37-2. Molecular formula: C25H24O6. Mole weight: 420.5.
Aurin
Aurin. Group: Biochemicals. Alternative Names: p-Rosolic acid; 4-[Bis (4-hydroxyphenyl) methylene]-2, 5-cyclohexadienone. Grades: Highly Purified. CAS No. 603-45-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H14O3. US Biological Life Sciences.
Worldwide
Aurintricarboxylic acid
5g Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C22H14O9. CAS No. 4431-00-9. Prepack ID 21152979-5g. Molecular Weight 422.34. See USA prepack pricing.
Aurintricarboxylic acid ammonium salt
Aurintricarboxylic acid ammonium salt (CAS# 569-58-4) is used in preparation method of amorphous silica-alumina catalyst for use in reaction of methanol and ammonia to produce monomethylamine, dimethylamine and trimethylamine. Alternative Names: azane;5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid. CAS No. 569-58-4. Molecular formula: C22H23N3O9. Mole weight: 473.43.
Aurintricarboxylic acid ammonium salt (Aluminon)
100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C22H23N3O9. CAS No. 569-58-4. Prepack ID 28596801-100g. Molecular Weight 473.43. See USA prepack pricing.
Aurintricarboxylic acid trisodium salt
Aurintricarboxylic acid trisodium salt. Alternative Names: AURINTRICARBOXYLIC ACID TRISODIUM SALT;aurintricaboxylicacidtrisodiumsalt;c.i.mordantviolet39;c.i.mordantviolet39,trisodiumsalt;chromevioletg;mordantviolet39;trisodium 5,5-(3-carboxylato-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylate);5,5'-[[4-Oxo. CAS No. 13186-45-3. Product ID: ACM13186453. Molecular formula: C22H11Na3O9. Mole weight: 488.29. Alfa Chemistry - ISO 9001:32057 Certified.
Auristatin E
Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160800-57-7. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-15582.
Auristatin E
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Alternative Names: Auristatin E. Grades: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01.
Auristatin F
Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 163768-50-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15583.
Auristatin F
Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99.
Aurkin A
Aurkin A is an allosteric inhibitor for the interaction between Aurora A Kinase (also known also Aurka) and TPX2, through targeting the TPX2 binding sites with Kd of 3.77 μM. Aurkin A can disrupt polyploidy induced by Alisertib (HY-10971) and increase apoptosis of tumor cells. Aurkin A can be used in research on mitosis and cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1534060-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125956.
Aurodox
It is produced by the strain of Streptomyces goldiniensis var. goldiniensis. Aurodox is a polyketide antibiotic originally isolated from S. goldiniensis, which inhibits bacterial protein biosynthesis by interrupting the functional cycle of Elongation Factor-Tu (EF-Tu). Aurodox is a type 3 secretion system (T3SS) inhibitor and growth promotor in poultry. It is active against Gram-positive bacteria, including B. megaterium, B. anthracis, and M. hominis (MICs = 0.06, 0.6, and 3-10 μg/ml, respectively). Alternative Names: Antibiotic X 5108; Goldinodox; Goldinomycin; 1-methyl-Mocimycin; Benzamide; CYT11387. Grades: ≥95%. CAS No. 12704-90-4. Molecular formula: C44H62N2O12. Mole weight: 810.97.
Aurofusarin
Dimeric naphthoquinone. Antibiotic activity. Mycotoxin. Toxic against mammalians and avian species. Analytical standard in food industry. Group: Biochemicals. Alternative Names: 4H-Naphtho[2,3-b]pyran, bimol. deriv.; 5,5-Dihydroxy-8,8-dimethoxy-2,2-dimethyl[7,7-bi-4H-naphtho[2,3-b]pyran]-4,4,6,6,9,9-hexone; Aurofusarin; NSC 244432. Grades: Highly Purified. CAS No. 13191-64-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Auroglaucin
It is produced by the strain of Aspergillus spp. Alternative Names: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38.
Aurora Kinase A active human, Recombinant
Aurora A kinase also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora A is activated by one or more phosphorylations and its activity peaks during the G2 phase to M phase transition in the cell cycle. Human aurora kinase a (genbank accession no. nm_003600), amino acids 2-403 with n-terminal his6-tag, mw=50 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Purity: > 90% (SDS-PAGE). ARK1. Mole weight: mol wt 50 kDa. Activity: ~17,000 units/mg protein. Form: aqueous solution. Source: baculovirus infected Sf9 cells. Species: Human. Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Pack: Minimum 50 ng protein/vial by Bradford. Cat No: NATE-0087.
Aurora kinase inhibitor-2
Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 331770-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112355.
A cell-permeable quinazoline compound that targets the ATP binding pocket and an adjacent cleft and acts as a potent and reversible inhibitor of Aurora A and Aurora B (IC50=110 and 130nM, respectively) with moderate to excellent selectivity among closely related 16-kinase panel (IC50=0.88, 1.03 and 1.79uM for Lck, Src and MEK1, respectively, and IC50>10uM for Cdk1/2/4, Plk1, Chk1). Blocks phosphorylation of Histone H3-Ser10 in Xenopus cycling egg extracts at 20uM, and reduces mitotic spindle assembly. Shown to repress kinetochore localization of BubR1, Cenp-E, and Mad2, and arrest the growth of proliferating tumor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 331771-20-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Aurothioglucose
Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gold thioglucose. CAS No. 12192-57-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-A0068.
Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53.
Australine hydrochloride
Australine hydrochloride. Alternative Names: AUSTRALINE HCL;AUSTRALINE HYDROCHLORIDE;AUSTRALINE, HYDROCHLORIDE, CASTANOSPERMUM AUSTRALE;(1R,2R,3R,7S,7AR)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE HCL;(1R,2R,3R,7S,7AR)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE, HYDROCHLORIDE;1H-Pyrrolizine-1. CAS No. 118396-02-4. Product ID: ACM118396024. Molecular formula: C8H16ClNO4. Mole weight: 225.67. Alfa Chemistry - ISO 9001:32057 Certified.