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| Product | Description | |
|---|---|---|
| AS2863619 free base | STAT5 activation enhanced by AS2863619 free base inhibits CDK8/19, which consequently activates the Foxp3 gene. Synonyms: AS2863619 (free base). Grade: 98%. CAS No. 2241300-50-3. Molecular formula: C16H12N8O. Mole weight: 332.32. |  |
| AS2863619 free base | AS2863619 free base enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 free base is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241300-50-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126675. |  |
| AS-35 | AS-35 is used as an antiallergic drug. It controls allergic diseases by inhibiting eosinophil activation. Uses: As-35 is used as an antiallergic drug. Synonyms: AS 35; AS35; AS-35; 3-(1H-Tetrazol-5-yl)-9-[[[2-propyl-3-hydroxy-4-(methylcarbonyl)phenyl]oxy]methyl]-4H-pyrido[1,2-a]pyrimidin-4-one; AS35; 4H-Pyrido(1,2-a)pyrimidin-4-one, 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-; 9-((4-Acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one. Grade: >98%. CAS No. 108427-72-1. Molecular formula: C21H20N6O4. Mole weight: 420.42. | |
| As48 | As48 is a selective TREM2 agonist with a KD value of 12.48 μM in TRIC binding assay. As48 binds near the TREM2 cleavage region, forms hydrogen bonds with Gly68, reduces conformational flexibility in regions 58-102, restricts protease accessibility to the cleavage site. As48 activates SYK phosphorylation, enhances microglial phagocytosis, and induces downstream calcium signaling in TREM2-expressing cells. As48 inhibits TREM2 ectodomain shedding without affecting ADAM10/17 protease activities. As48 can be used for the research of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1214405-38-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-182702. | |
| AS601245 | Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| AS601245 | AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. Synonyms: AS601245; AS-601245; AS 601245. Grade: >98%. CAS No. 345987-15-7. Molecular formula: C20H16N6S. Mole weight: 372.45. | |
| AS601245 | AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 345987-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11010. | |
| AS-601811 | AS-601811 is a 5-α reductase (type 1) inhibitor developed for the treatment of acne. Synonyms: 4,8-dimethyl-1,2,5,6-tetrahydrobenzo[f]quinolizin-3-one; AS-601811; AS 601811; AS601811; UNII-LIV8A6AE5F. Grade: >98%. CAS No. 194979-95-8. Molecular formula: C15H17NO. Mole weight: 227.307. | |
| AS 602801 | AS 602801 is a novel, orally active inhibitor of JNK. It blocked T-lymphocyte proliferation and induced apoptosis. Synonyms: AS602801; AS-602801; AS 602801; PGL5001; PGL-5001; PGL 5001; Bentamapimod. Grade: >98%. CAS No. 848344-36-5. Molecular formula: C25H23N5O2S. Mole weight: 457.55. | |
| AS-604850 | AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα. Synonyms: AS604850; AS 604850; AS-604850. PI3K gamma inhibitor; PI 3-Kgamma Inhibitor II; (5E)-5-[(2,2-Difluoro-1,3-benzodioxol-5-YL)methylene]-1,3-thiazolidine-2,4-dione. Grade: 98%. CAS No. 648449-76-7. Molecular formula: C11H5F2NO4S. Mole weight: 285.211. | |
| AS 605240 | AS 605240. Group: Biochemicals. Grades: Purified. CAS No. 648450-29-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AS-605240 | AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis. Synonyms: AS 605240; AS605240; AS-605240. Grade: 0.98. CAS No. 648450-29-7. Molecular formula: C12H7N3O2S. Mole weight: 257.267. | |
| AS-605240 | AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC50 of 8 nM, and a Ki of 7.8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 648450-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10109. | |
| AS-605240 potassium salt | Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer. AS-605240 inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively. AS-605240 also inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells with an IC50 value of 90 nM. AS-605240 potassium salt is the potassium salt form of AS-605240, which increase the water-solubility. Synonyms: AS-605240. Grade: ≥98%. Molecular formula: C12H6N3O2S·K. Mole weight: 295.4. | |
| AS8351 | AS8351 (NSC51355) is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC51355. CAS No. 796-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100744. | |
| AS 8351 | AS 8351 has been found to show the activity in inducing reprogramming of human fetal lung fibroblasts into functional cardiomyocytes. Synonyms: AS-8351; AS-8351; AS-8351; 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone. Grade: ≥98% by HPLC. CAS No. 796-42-9. Molecular formula: C17H13N3O2. Mole weight: 291.30. | |
| AS-85 | AS-85 is a potent inhibitor of ASH1L histone methyltransferase with an IC50 of 0.6 μM. AS-85 has anti-leukemic activity and strongly binds to the ASH1L SET domain, with a Kd of 0.78 μM. Synonyms: 3-Azetidinecarboxamide, N-[[3-[3-(aminothioxomethyl)phenyl]-1-[1-[(trifluoromethyl)sulfonyl]-4-piperidinyl]-1H-indol-6-yl]methyl]-. CAS No. 2323623-80-7. Molecular formula: C26H28F3N5O3S2. Mole weight: 579.66. | |
| AS-99 | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50 =?0.79?μM, Kd =?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. Molecular formula: C27H31ClF3N5O3S2. Mole weight: 630.14. | |
| AS-99 free base | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50=?0.79?μM, Kd=?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. CAS No. 2323623-93-2. Molecular formula: C27H30F3N5O3S2. Mole weight: 593.68. | |
| AS-99 TFA | AS-99 is a potent and selective ASH1L histone methyltransferase inhibitor (IC50=?0.79?μM, Kd=?0.89?μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. Synonyms: AS-99 (TFA); AS-99 TFA; HY-141429A; MS-31187; CS-0227299. Grade: ≥98%. Molecular formula: C29H31F6N5O5S2. Mole weight: 707.71. | |
| AS-99 TFA | AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3115178-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141429A. | |
| Asacoumarin A | Asacoumarin A. Alternative Names: 7-[(2E,6Z)-5,8- dihydroxy-3,7,11-trimethyldodeca-2,6,10-trienoxy]chromen-2-one. CAS No. 122617-02-1. Purity: >95.0%. Product ID: FFC-AR-122617021. Molecular formula: C24H30O5. Mole weight: 398.49. IUPAC Name: 7-(5,8-dihydroxy-3,7,11-trimethyldodeca-2,6,10-trienoxy)chromen-2-one. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Asapiprant | Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-555739. CAS No. 932372-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16763. | |
| Asarinin | Asarinin. Group: Biochemicals. CAS No. 133-04-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Asarinin | Asarinin. Group: Biochemicals. Alternative Names: (-)-Episesamin. Grades: Plant Grade. CAS No. 133-04-0. Pack Sizes: 20mg. Molecular Formula: C20H18O6, Molecular Weight: 354.353. US Biological Life Sciences. | Worldwide |
| Asarone | Asarone. Group: Biochemicals. Grades: Plant Grade. CAS No. 2883-98-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asarylaldehyde | Asarylaldehyde. Group: Biochemicals. Grades: Plant Grade. CAS No. 4460-86-0, 14374-62-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Asarylaldehyde | Asarylaldehyde. Alternative Names: Asaronaldehyde, Asaraldehyde, Azarylaldehyde, Gazarin, 2,4,5-TRIMETHOXYBENZALDEHYDE, Spectrum_000818, 3,4,6-Trimethoxybenzaldehyde, Benzaldehyde, 2,4,5-trimethoxy-, Spectrum2_000386, Spectrum3_000170, Spectrum4_001759, Spectrum5_000618, CCRIS 1296, BSPBio_001639, KBioGR_002238, KBioSS_001298, SPECTRUM200208, HSDB 4502, MLS002473312, SPBio_000571. CAS No. 14374-62-0. Purity: 96%. Product ID: ACM14374620. Molecular formula: C10H12O4. Mole weight: 196.19988. IUPAC Name: 2,4,5-trimethoxybenzaldehyde. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Asatone | Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 38451-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N6826. | |
| ASB14780 | ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1069046-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119019. | |
| ASB14780 | ASB14780 is a potent and oral inhibitor of cytosolic phospholipase A2α (cPLA2α; IC50 = 0.020 μM in vitro and 0.54 - 0.64 μM in whole blood assay) with anti-inflammatory property in ear edema and asthma models. ASB14780 has the potential for the treatment of nonalcoholic fatty liver diseases including fatty liver and hepatic fibrosis. ASB14780 significantly attenuated expression of smooth muscle a-actin (a-SMA) protein and the mRNA expression of collagen 1a2, a-SMA and TGFb1 in the liver, as well as the expression of monocyte/macrophage markers. Synonyms: ASB14780; ASB 14780; ASB-14780; 3-(3-Phenethyl-1-(4-phenoxyphenyl)-1H-indol-5-yl)propanoic acid, 2-amino-2-(hydroxymethyl)-1,3-propanediol; 3-[1-(4-Phenoxyphenyl)-3-(2-phenylethyl)-1H-indol-5-yl]propanoic acid, 2-amino-2-(hydroxymethyl)-1,3-propanediol. Grade: 99%. CAS No. 1069046-00-9. Molecular formula: C31H27NO3.C4H11NO3. Mole weight: 582.69. | |
| ASC-69 | ASC-69 (APY69)is a potent and promising?PD-1/PD-L1 small-molecule inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APY69. CAS No. 1216665-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W771599. | |
| Ascalin | Ascalin is produced by Allium cepa var. aggregatum. It has antifungal activity against B.cinerea. Ascalin also inhibits HIV-1 reverse transcriptase with an IC50 of 10 μM. | |
| Ascamycin | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. The MIC values of Ascamycin against Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei are 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL, respectively. Synonyms: (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine; 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine; 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine; 5'-O-{[(2S)-2-Amino-1-hydroxypropylidene]sulfamoyl}-2-chloroadenosine. Grade: ≥95%. CAS No. 91432-48-3. Molecular formula: C13H18ClN7O7S. Mole weight: 451.84. | |
| Ascaphin-1 | Ascaphin-1 is produced by Ascaphus truei. Ascaphin-1 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-1M | Ascaphin-1M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-2 | Ascaphin-2 is isolated from norepinephrine-stimulated skin secretions of A. truei and was shown to possess growth inhibitory activity against Escherichia coli and Staphylococcus aureus. | |
| Ascaphin-3 | Ascaphin-3 is produced by Ascaphus truei. Ascaphin-3 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-3M | Ascaphin-3M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-4 | Ascaphin-4 is produced by Ascaphus truei. Ascaphin-4 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-4M | Ascaphin-4M is produced by Alsodes montanus. It has antimicrobial activity. | |
| Ascaphin-5 | Ascaphin-5 is produced by Ascaphus truei. Ascaphin-5 is an antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. It has a very week hemolytic activity. | |
| Ascaphin-5M | Ascaphin-5M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Synonyms: Gly-Ile-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Thr-Leu-Ile-Lys-Thr-Val-Ala-Ser-His-Ile-Ala-Asn-Gln. Grade: >98%. Molecular formula: C116H195N33O32. Mole weight: 2564.03. | |
| Ascaphin-6 | Ascaphin-6 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Synonyms: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Glu; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamic acid. Grade: >98%. CAS No. 722538-44-5. Molecular formula: C118H195N31O33. Mole weight: 2576.03. | |
| Ascaphin-7 | Ascaphin-7 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows higher potency against Gram-negative bacteria than against Gram-positive bacteria and has a very week hemolytic activity. Synonyms: H-Gly-Phe-Lys-Asp-Trp-Ile-Lys-Gly-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Ser-Ile-Ala-Asn-Gln-OH; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysylglycyl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-seryl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grade: ≥98%. CAS No. 722538-45-6. Molecular formula: C118H196N32O32. Mole weight: 2575.04. | |
| Ascaphin-7M | Ascaphin-7M is an antimicrobial peptide produced by Alsodes montanus (North America inland frog). It has antimicrobial activity. Synonyms: Gly-Phe-Lys-Asp-Trp-Ile-Lys-Ser-Ala-Ala-Lys-Lys-Leu-Ile-Lys-Thr-Val-Ala-Ser-Asn-Ile-Ala-Asn-Gln; glycyl-L-phenylalanyl-L-lysyl-L-aspartyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-seryl-L-alanyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-valyl-L-alanyl-L-seryl-L-asparaginyl-L-isoleucyl-L-alanyl-L-asparaginyl-L-glutamine. Grade: >98%. Molecular formula: C120H199N33O33. Mole weight: 2632.11. | |
| Ascaphin-8 | Ascaphin-8 is an antimicrobial peptide produced by Ascaphus truei (Coastal tailed frog). It shows similar potency against Gram-negative bacteria and Gram-positive bacteria and has a high hemolytic activity. Synonyms: Gly-Phe-Lys-Asp-Leu-Leu-Lys-Gly-Ala-Ala-Lys-Ala-Leu-Val-Lys-Thr-Val-Leu-Phe-NH2; glycyl-L-phenylalanyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-valyl-L-lysyl-L-threonyl-L-valyl-L-leucyl-L-phenylalaninamide. Grade: ≥95%. CAS No. 722538-46-7. Molecular formula: C97H164N24O22. Mole weight: 2018.53. | |
| Ascaridole | An organic peroxide which constitutes 60-80% of oil of chenopodium. Anthelmintic. Group: Biochemicals. Alternative Names: 1-Methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene. Grades: Highly Purified. CAS No. 512-85-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Ascaridole | Ascaridole is an anthelmintic and also has antimalarial activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 512-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-118494. | |
| Asciminib | Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Uses: Tyrosine kinase inhibitors. Synonyms: ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide. CAS No. 1492952-76-7. Molecular formula: C20H18ClF2N5O3. Mole weight: 449.843. | |
| Asciminib | Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABL001. CAS No. 1492952-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010. | |
| Asciminib-[15N,d4] | Asciminib-[15N,d4] is the labelled analogue of Asciminib. Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Synonyms: [15N,2H4]-Asciminib; (R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)nicotinamide[15N,2H4]. Molecular formula: C20H14D4ClF2N4[15N]O3. Mole weight: 454.86. | |
| Asciminib hydrochloride | Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABL001 hydrochloride. CAS No. 2119669-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010A. | |
| asclepain | From the latex of milkweed, Asclepias syriaca. It has multiple forms, and is in peptidase family C1 (papain family). Group: Enzymes. Enzyme Commission Number: EC 3.4.22.7. CAS No. 37288-80-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4246; asclepain; EC 3.4.22.7; 37288-80-5. Cat No: EXWM-4246. |  |
| Ascochin | Ascochin is a fungal metabolite found in Ascochyta, which has antifungal, antibacterial and phytotoxic activities. Synonyms: (S)-(+)-Ascochin. Grade: >95% by HPLC. CAS No. 935699-58-4. Molecular formula: C12H10O5. Mole weight: 234.2. | |
| Ascochitine | Ascochitine is an antibiotic produced by Ascochita fabae and Asc. pisi. It is mainly resistant to fungi such as Xanthomonas oryzae and Xanthomonas oryzae, and has a control effect on some diseases of rice and tomato. Molecular formula: C15H16O5. Mole weight: 276.28. | |
| Ascochlorin | Ascochlorin is an antibiotic produced by Ascochyta viciae. It has anti-candida albicans activity. It can inhibit Newcastle disease virus and herpes simplex virus plaque formation in chicken embryo fibroblast culture. Synonyms: Ilicicolin D. Grade: >98%. CAS No. 26166-39-2. Molecular formula: C23H29ClO4. Mole weight: 404.93. | |
| Ascochlorin A | Ascochlorin A, a potent hDHODH inhibitor (KD = 3.29 μM), is used for the treatment of triple-negative breast cancer. Synonyms: Acremochlorin A. CAS No. 2550720-02-8. Molecular formula: C23H31ClO4. Mole weight: 406.94. | |
| Ascochlorin (Antibiotic LL-Z 1272 gamma) | The antitumour fungal metabolite ascochlorin specifically inhibits matrix metalloproteinase-9 (MMP9) activity through suppression of activator protein-1 (AP-1) dependent induction of MMP-9 gene expression. Via AP-1 suppression ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses. Group: Biochemicals. Alternative Names: Antibiotic LL-Z 1272 gamma. Grades: Highly Purified. CAS No. 26166-39-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Ascofuranone | Ascofuranone is an antibiotic produced by Ascochyta viciae. On the agar plate, it can inhibit the plaque formation of some viruses, and is not resistant to bacteria and other microorganisms. Oral administration in rats can reduce blood lipids. Grade: >98%. CAS No. 38462-04-3. Molecular formula: C23H29ClO5. Mole weight: 420.93. | |
| Ascomatic acid | It is a new dibenzofuran and depside from the Lichen Bunodophoron patagonicum. Synonyms: 2-Dibenzofurancarboxylic acid, 3,7-dimethoxy-1,9-dimethyl-; 3,7-dimethoxy-1,9-dimethyldibenzofuran-2-carboxylic acid. CAS No. 93796-74-8. Molecular formula: C17H16O5. Mole weight: 300.31. | |
| Ascomycin | Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells.Ascomycin (also known as Immunomycin, FR 900520, and FK-520) is an analog of tacrolimus (FK-506) with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases.Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells. Paul, C., et al. "Ascomycins: promising agents for the treatment of inflammatory skin diseases." Expert Opin. Investig. Drugs. 9: 69-77 (2000). Moll.the compounds." J. Infect. Dis. 191: 1342-1349 (2005).FK-520 might be a substrate for P-glycoprotein; expression of P-glycoprotein in yeast cells resulted in resistance to growth inhibition by FK-520. Raymond, M., et al. "Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520." Mol. Cell Biol. 14: 277-286 (1994). Group: Biochemicals. Alternative Names: Immunomycin; FK-520; FR-520; NSC-106410; FR 900520; L 683590; Changchuanmycin. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C43H69NO12, Molecular Weight: 792.01. US Biological Life Sciences. | Worldwide |
| Ascomycin | Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Immunomycin; FR-900520; FK520. CAS No. 104987-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg. Product ID: HY-13557. | |
| Ascophyllum nodosum extract | Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Ascophyllum nodosum, Fucaceae. Synonyms: Fucoidan, ex ascophyllum nodosum; Ascophyllum nodosum, ext.; Stimax; Stimax Growth. CAS No. 84775-78-0. | |
| ascopyrone tautomerase | This enzyme catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose. The other enzymes involved in this pathway are EC 4.2.1.110 (aldos-2-ulose dehydratase), EC 4.2.1.111 (1,5-anhydro-D-fructose dehydratase) and EC 4.2.2.13 [exo-(1?4)-α-D-glucan lyase]. Ascopyrone P is an anti-oxidant. Group: Enzymes. Synonyms: ascopyrone isomerase; ascopyrone intramolecular oxidoreductase; 1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase; APM tautomerase; ascopyrone P tautomerase; APTM. Enzyme Commission Number: EC 5.3.2.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5487; ascopyrone tautomerase; EC 5.3.2.7; ascopyrone isomerase; ascopyrone intramolecular oxidoreductase; 1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase; APM tautomerase; ascopyrone P tautomerase; APTM. Cat No: EXWM-5487. | |
| ascorbate ferrireductase (transmembrane) | A diheme cytochrome that transfers electrons across a single membrane, such as the outer membrane of the enterocyte, or the tonoplast membrane of the plant cell vacuole. Acts on hexacyanoferrate(III) and other ferric chelates. Group: Enzymes. Synonyms: cytochrome b561 (ambiguous). Enzyme Commission Number: EC 7.2.1.3 (Formerly EC 1.16.5.1). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1077; ascorbate ferrireductase (transmembrane); EC 1.16.5.1; cytochrome b561 (ambiguous). Cat No: EXWM-1077. | |
| Ascorbate oxidase, Cucurbit sp. | Ascorbate oxidase, Cucurbit sp., also known as vitamin C oxidase, is a REDOX enzyme involved in the regulation of extracellular matrix. Ascorbate oxidase catalyzes the reaction of ascorbic acid and oxygen to produce dehydroascorbic acid[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASO, Cucurbit sp. CAS No. 9029-44-1. Pack Sizes: 100 U; 500 U; 1000 U. Product ID: HY-P2742. | |
| Ascorbic Acid | Ascorbic Acid. Group: Food ingredients. Pack Sizes: 25kgs Boxes. |  |
| Ascorbic Acid | Ascorbic Acid. CAS No. 50-81-7. VIGON Item # 508696. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Ascorbic Acid | Ascorbic Acid. Category ACIDS. Pack Sizes Drums/ bags/ bulk |  |
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