A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Asenapine-13C,d3 α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tris(2-methylpropanoate) Is a metabolite of Asenapine (A788000), an combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Asenapine α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tris(2-methylpropanoate) is a metabolite of Asenapine (A788000), an combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Asenapine hydrochloride
Asenapine hydrochloride, also called Org 5222 and HSDB 8061, shows high affinity for numerous receptors including 5-HT receptor and adrenergic receptor. (pKi: 5-HT1A= 8.6, 5-HT1B= 8.4, 5-HT2A= 10.2, 5-HT2B= 9.8, 5-HT2C= 10.5, 5-HT5A= 8.8, 5-HT6= 9.5, and. Synonyms: Asenapine (hydrochloride); 1412458-61-7; DTXSID10678678; CS-1053; HY-16567; W-6082; CS 1053; HY 16567; W 6082; CS1053; HY16567; W6082; (3aS,12bS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole--hydrogen chloride (1/1). CAS No. 1412458-61-7. Molecular formula: C17H17Cl2NO. Mole weight: 322.23.
AsenapineImpurity1
AsenapineImpurity1. Uses: For analytical and research use. Alternative Names: 5-chloro-2-methyl-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole-1,3(2H)-dione. CAS No. 129385-61-1. Molecular formula: C17H10ClNO3. Mole weight: 311.72. Catalog: APB129385611.
Asenapine N-oxide
Asenapine N-oxide. Alternative Names: (3aR-trans)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole 2-Oxide. CAS No. 128949-51-9. Product ID: ACM128949519. Molecular formula: C17H16ClNO2. Mole weight: 301.77. Alfa Chemistry - ISO 9001:32057 Certified.
Asenapine maleate
Asenapine Maleate is a 5-HT receptor antagonist used for the treatment of acute schizophrenia and bipolar mania. It is a second-generation (atypical) antipsychotic agent. Synonyms: (3aR,12bR)-rel-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-Butenedioate; trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole; Org 5222. Grade: >98%. CAS No. 85650-56-2. Molecular formula: C21H20ClNO5. Mole weight: 401.84.
Asenapine maleate
Asenapine (Org 5222) maleate, a brain-penetrant atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine maleate can be used in the research of schizophrenia and bipolar disorder[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Org 5222 maleate. CAS No. 85650-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-11100.
Asenapine Maleate
Asenapine Maleate is a 5-HT receptor antagonist developed for the treatment of acute schizophrenia and bipolar mania. Group: Biochemicals. Alternative Names: (3aR, 12bR)-rel-5-Chloro-2, 3, 3a, 12b-tetrahydro-2-methyl-1H-dibenz[2, 3:6, 7]oxepino[4, 5-c]pyrrole (2Z)-2-Butenedioate; trans-5-Chloro-2, 3, 3a, 12b-tetrahydro-2-methyl-1H-Dibenz[2, 3:6, 7]oxepino[4, 5-c]pyrrole; Org 5222. Grades: Highly Purified. CAS No. 85650-56-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Asenapine N-b-D-glucuronide
Asenapine N-b-D-glucuronide is a metabolite derived from the antipsychotic compound asenapine with utilization encompassing compound metabolism analysis, drug-drug interaction assessment and pharmacokinetic investigations surrounding asenapine. Molecular formula: C23H24ClNO7. Mole weight: 461.89.
Asenapine N-oxide
Asenapine N-oxide. Group: Biochemicals. Alternative Names: (3aR-trans)-5-Chloro-2, 3, 3a, 12b-tetrahydro-2-methyl-1H-dibenz[2, 3:6, 7]oxepino[4, 5-c]pyrrole 2-oxide. Grades: Highly Purified. CAS No. 128949-51-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C17H16ClNO2. US Biological Life Sciences.
Worldwide
Asenapine-N-oxide
A metabolite of Asenapine. Synonyms: (3aR-trans)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole 2-Oxide. Grade: > 95%. CAS No. 128949-51-9. Molecular formula: C17H16ClNO2. Mole weight: 301.78.
Asenapine O-sulfate
A metabolite of Asenapine. Synonyms: Asenapine 11-Hydroxysulfate. Grade: > 95%. CAS No. 1399103-21-9. Molecular formula: C17H16ClNO5S. Mole weight: 381.84.
A set of flexible heating components(bluetooth)
A set of flexible heating components(bluetooth).
Asfotase alfa
Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ENB-0040. CAS No. 1174277-80-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108786.
AS-hepc2
AS-hepc2 is an antimicrobial peptide produced by Acanthopagrus schlegelii (Black porgy). It has antimicrobial activity. Synonyms: Hepcidin AS-hepc2; Ser-Pro-Ala-Gly-Cys-Arg-Phe-Cys-Cys-Gly-Cys-Cys-Pro-Asn-Met-Arg-Gly-Cys-Gly-Val-Cys-Cys-Arg-Phe (Disulfide bridge: Cys5-Cys22, Cys8-Cys21, Cys9-Cys18, Cys11-Cys12). Grade: >98%. Molecular formula: C98H148N34O27S9. Mole weight: 2523.01.
Ashimycin A
Ashimycin A is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Synonyms: 2,4-Dicarbamimidamido-3,5,6-trihydroxycyclohexyl 2-C-carboxypentofuranosyl-(1->4)-2-deoxy-2-(methylamino)hexopyranosyl-(1->2)-5-deoxy-3-C-formylpentofuranoside. CAS No. 123482-11-1. Molecular formula: C27H47N7O18. Mole weight: 757.70.
Ashimycin B
Ashimycin B is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Synonyms: D-Streptamine, O-2-deoxy-2-((hydroxyacetyl)methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-. CAS No. 123482-12-2. Molecular formula: C23H41N7O14. Mole weight: 639.61.
Ashwaganda P.E. 1.5% & 2.5% Withanaloids UV
Ashwaganda P.E. 1.5% & 2.5% Withanaloids UV.
CA, FL & NJ
Ashwagandha Extract
Ashwagandha Extract. Applications: Used for men health care products, dietary supplements, can improve human immunity. Group: Others. Synonyms: Ashwagandha Extract; Crateagus pinnatifida. Purity: 2-10% Withanolides by HPLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root or Leaf. Species: Crateagus pinnatifida. Ashwagandha Extract; Crateagus pinnatifida; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-078.
Ashwagandha Powder
Ashwagandha Powder. Alternative Names: Withania somnifera, Indian Ginseng, Winter Cherry, Ajagandha, Ashvagandha, Asgandh. CAS No. 329-62-4. Product ID: DS329624. Molecular formula: C28H38O6. Mole weight: 470.6 g/mol. Alfa Chemistry - ISO 9001:32057 Certified.
Asialo, galactosylated, fucosylated, biantennary (G1F) - a formidable glycan structure with therapeutic potential, capable of wrangling a plethora of diseases, ranging from the insidious grip of cancer to the fiery inflammation. Studies indicate that G1F galvanizes antibody-dependent cellular cytotoxicity (ADCC), augments pharmacokinetics and reinforces the stability of recombinant proteins. It is a versatile tool in glycoengineering, which can be exploited to optimize the therapeutic properties of therapeutic proteins. Molecular formula: C62H104N4O45. Mole weight: 1625.49.
Asialo-GM1-pentasaccharide-APD-HSA
Asialo-GM1-pentasaccharide-APD-HSA is an innovative biomedical compound, unveiling its paramount significance in the realm of research for specific ailments and conditions. Engineered meticulously to intricately engage Asialo-GM1 receptors with profound efficacy, this prodigious compound steadfastly facilitates compound conveyance. Synonyms: Asialo GM1 oligosaccharide.
Asian Ginseng Extract (Standard)
Ginseng Extract is extracted from the root and leaf of Panax ginseng C. A. Mey, which is the specie of slow-growing perennial plants with fleshy roots, belonging to the genus Panax of the family Araliaceae. Ginseng is found only in the northern hemisphere, in eastern Asia (mostly Korea, northeastern China, Bhutan and eastern Siberia), typically in cooler climates. Applications: 1.ginseng extract to alleviate motion sickness, pregnancy, post-operative nausea and vomiting2.mainly suitable for coronary heart disease, angina pectoris, heart rate is too slow, too fast, premature ventricular bo, blood pressure disorder, neurasthenia, menopausal syndrome. Group: Others. CAS No. Gins.oside Rb1: 41753-43-9Ginsenoside Rb2: 11021-13-9Ginsenoside Re: 52286-59-6Ginsenoside Rc: 11021-14-0Ginsenoside Rf: 52286-58-5. Purity: 10.0%-80.0% Ginsenoside UV. Mole weight: Ginsenoside Rg1: 801.01Ginsenoside Rb1: 1109.29Ginsenoside Rb2: 1079.26Ginsenoside Re: 947.15Ginsenoside Rc: 1079.26Ginsenoside Rf: 801.01. Asian Ginseng Extract (Standard); Ginsenoside Rg1: 22427-39-0Ginsenoside Rb1: 41753-43-9Ginsenoside Rb2: 11021-13-9Ginsenoside Re: 52286-59-6Ginsenoside Rc: 11021-14-0Ginsenoside Rf: 52286-58-5; Ginsenoside Rg1: C42H72O14Ginsenoside Rb1: C54H92O23Ginsenoside Rb2: C53H90O22Ginsenoside Re: C48H82O18Ginsenoside Rc: C53H90O22Ginsenoside Rf: C42H72O14. Cat No: EXTW-020.
Asiatic acid
Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 464-92-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0194.
Asiatic acid
Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing. Asiatic acid has the potential for skin cancer treatment. Asiatic acid also has anti-inflammatory activities. Uses: Antihyperlipidemic. Synonyms: Dammarolic acid; Asiantic acid; NSC 166063; 2,3,23-trihydroxyurs-12-en-28-oic acid. Grade: > 98 %. CAS No. 464-92-6. Molecular formula: C30H48O5. Mole weight: 488.70.
Asiatic acid
Asiatic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 464-92-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C30H48O5. US Biological Life Sciences.
Worldwide
Asiatic acid (Standard)
Asiatic acid (Standard) is the analytical standard of Asiatic acid. This product is intended for research and analytical applications. Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 464-92-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0194R.
Asiaticoside
Asiaticoside. Synonyms: Madecassol. CAS No. 16830-15-2. Product ID: CDC10-0035. Molecular formula: C48H78O19. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Asiaticoside; CDC10-0035; 16830-15-2; C48H78O19; Madecassol; 240-851-7; MFCD06642601; 16830-15-2. Grade: Analytical standard. Purity: ≥98.5% (HPLC). EC Number: 240-851-7. Physical State: Crystals. Solubility: DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly). Quality Level: 100. Storage: under inert gas (nitrogen or Argon) at 2-8°C. Boiling Point: 1017.5±65.0 °C(Predicted). Melting Point: 235-238°C. Density: 1.44±0.1 g/cm3(Predicted). Product Description: Asiaticoside is a saponin with significant wound and burn healing activity, used to study potential treatments.
Asiaticoside
Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor. Group: Biochemicals. Alternative Names: Blastostimulina, Centelase, Emdecassol, Madecassol, Marticassol, FK1080, BRN 0078195, NSC 166062. Grades: Highly Purified. CAS No. 16830-15-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C48H78O19. US Biological Life Sciences.
Worldwide
Asiaticoside
Asiaticoside is a natural triterpenoid found in the herbs of Centella asiatica (L.) Urban. Asiaticoside shows anxiolytic-like and antidepressant-like effects. Asiaticoside may be useful for the anti-gastric ulcers and also can be used in cosmetic material. Uses: Anti-infective agents. Synonyms: Madecassol. Grade: >95%. CAS No. 16830-15-2. Molecular formula: C48H78O19. Mole weight: 959.13.
Asiaticoside
Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties. Uses: Scientific research. Category: Signaling pathways. CAS No. 16830-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0439.
Asiaticoside B
Asiaticoside B is a 9,19-cycloartane triterpene glycoside found in Actaea asiatica. Asiaticoside B has cytotoxicity against HepG2 and MCF-7 cancer cells with IC50 values of 9.74 μM and 8.32 μM, respectively[1]. Uses: Scientific research. Category: Natural products. CAS No. 125265-68-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N5052.
Asiaticoside B
Asiaticoside B. Group: Biochemicals. CAS No. 125265-68-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Asiaticoside (Standard)
Asiaticoside (Standard) is the analytical standard of Asiaticoside. This product is intended for research and analytical applications. Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties. Uses: Scientific research. Category: Signaling pathways. CAS No. 16830-15-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0439R.
ASIC1a antagonist-1
ASIC1a antagonist-1 (Compound 5b) is an orthosteric noncompetitive Acid sensing ion channels 1a (ASIC1a) antagonist with an IC50 of 27 nM (pH 6.7). ASIC1a antagonist-1 shifts pH dependence of ASIC1a activation and inhibits its maximal evoked response. ASIC1a antagonist-1 completely inhibits long-term potentiation (LTP) induction in CA3-CA1 pathway. ASIC1a antagonist-1 can be used for brain diseases and pathologies research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1787243-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176550.
ASIC Channel Modulator II, GMQ (2-guanidine-4-methylquinazoline, Acid-sensing Ion Channel Modulator II)
A positively charged guanidium-containing quinazoline that modulates ASIC function by blocking acid-induced maximal peak current as well as by altering ASICs pH dependence for activation and inactivation, enabling a partial, but sustained ASIC3 activation around neutral pH (4.4% of pH 5-induced peak current with 1mM GMQ at pH 7.4), which is inhibitable by Amiloride. Intraplantar paw injection (10ul 100uM) is reported to elicit a pain response in asic3+/+, but not asic3-/-, mice in vivo. GMQ targeting area appears to overlap with Amiloride binding site in the pore region, but is distinct from ASIC calcium binding site. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?. US Biological Life Sciences.
Worldwide
AsiG I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. A↑CCGGT TGGCC↓A. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Arthrobacter species G. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1023EN.
Asimadoline
Asimadoline is a κ opioid receptor agonist with less brain-penetrant ability. Asimadoline is the potential treatment of irritable bowel syndrome. Synonyms: N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methyl-2,2-diphenylacetamide. CAS No. 153205-46-0. Molecular formula: C27H30N2O2. Mole weight: 414.549.
Asimadoline hydrochloride
Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride has low permeability across the blood brain barrier and has peripheral anti-inflammatory actions. Asimadoline hydrochloride ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EMD-61753 hydrochloride. CAS No. 185951-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107384A.
Asimilobine
Asimilobine is a natural alkaloid compound found in several plants. Synonyms: (R)-5,6,6a,7-Tetrahydro-1-methoxy-4H-dibenzo[de,g]quinolin-2-ol; 1-Methoxy-6abeta-noraporphin-2-ol. Grade: >98%. CAS No. 6871-21-2. Molecular formula: C17H17NO2. Mole weight: 267.322.
Asivatrep
Asivatrep (PAC-14028) is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAC-14028. CAS No. 1005168-10-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12777.
ASK120067
ASK120067, a third generation EGFR-TKI for non-small cell lung cancer (NSCLC) research, is a potent and orally active EGFRT790M inhibitor (IC50 = 0.3 nM) with selectivity over EGFRWT (IC50 = 6.0 nM). Synonyms: 2-Propenamide, N-[5-[[5-chloro-4-(2-naphthalenylamino)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-; N-(5-{[5-Chloro-4-(2-naphthylamino)-2-pyrimidinyl]amino}-2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxyphenyl)acrylamide. Grade: ≥98%. CAS No. 1934259-00-3. Molecular formula: C29H32ClN7O2. Mole weight: 546.06.
ASK1-IN-1
ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC50=138 nM; Biochemical IC50=21 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2411382-24-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133554.
ASK1-IN-1
ASK1-IN-1 is a CNS-penetrant ASK1 inhibitor, with good potency (cell IC50 = 138 nM; Biochemical IC50 = 21 nM). Grade: 99%. CAS No. 2411382-24-4. Molecular formula: C23H21N7O. Mole weight: 405.41.
ASK1-IN-2
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 32.8 nM. It can potentially be used as a therapeutic strategy for ulcerative colitis. Synonyms: ASK1-IN-2; 2541792-70-3; EX-A7533; AKOS040759790; MS-25802; HY-131969; CS-0145639. Grade: 98%. CAS No. 2541792-70-3. Molecular formula: C19H17FN6O. Mole weight: 364.38.
ASK1-IN-2
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2541792-70-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131969.
ASK1-IN-6
ASK1-IN-6 is a selective, orally active, and blood-brain barrier penetrant inhibitor of ASK1 (biochemical IC50: 7 nM; cellular IC50: 25 nM). ASK1-IN-6 exhibits anti-inflammatory and can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2407451-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160939.
ASM-024
ASM-024 is a small synthetic compound and a potent nicotinic receptor agonist developed for airway inflammatory diseases as the primary target therapeutic indication. It acts as a dual anti-inflammatory and bronchodilating agent in preclinical models. Synonyms: 1H-1,4-Diazepinium, 1,1-diethylhexahydro-4-phenyl; di-ethyl-4-phenylhomopiperazinium. Grade: >98.0%. CAS No. 1609534-88-4. Molecular formula: C15H25N2. Mole weight: 233.37.
ASMC Transfection Reagent
Transfection Reagent for ASMC Human Aortic Smooth Muscle Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1708.
Nevada, Texas, USA
ASN-002
ASN-002 (Gusacitinib) is a dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with an IC50 value of 5-46 nM. It has anti-cancer activity. Synonyms: Gusacitinib. Grade: ≥98% by HPLC. CAS No. 1425381-60-7. Molecular formula: C24H28N8O2. Mole weight: 460.5.
ASN007
ASN007 (ERK-IN-3) is a potent and orally active inhibitor of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC50 values. ASN007 exhibits significant anti proliferative activity against various tumor cells. ASN007 can be used for the research of cancers driven by RAS mutations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ERK-IN-3. CAS No. 2055597-12-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136579.
ASN 07115873 is an anti-ZIKV compound (IC50: 189.2 pM), and can be used for antiviral research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 626220-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156314.
Asn(Acm)-Desmopressin
Asn(Acm)-Desmopressin is an impurity of Desmopressin, which is a synthetic octapeptide and an analog of the human hormone arginine vasopressin with antidiuretic and coagulant activities. Synonyms: Deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl(Acm)-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; deamino-Cys-Tyr-Phe-Gln-Asn(Acm)-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Mpr-Tyr-Phe-Gln-Asn(Acm)-Cys-Pro-D-Arg-Gly-NH2 (Disulfide Bridge Mpr1-Cys6); [Asn(Acm)]5-Desmopressin; Asn5(Acm)-Desmopressin; N4.5-[(Acetylamino)methyl]desmopressin; Desmopressin EP Impurity F. Grade: ≥95%. Molecular formula: C49H69N15O13S2. Mole weight: 1140.30.
Asnuciclib
Asnuciclib (CDKI-73; LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. Asnuciclib down-regulates the RNAPII phosphorylation. Asnuciclib is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CDKI-73; LS-007. CAS No. 1421693-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12445.
a-Solanine
a-Solanine, an organic compound existing naturally in potatoes and tomatoes, has garnered attention in the field of biomedicine. Its viability in combating specific forms of cancer has been extensively explored. Extensive research illustrates that a-Solanine showcases exceptional anticancer traits by restraining tumor proliferation and stimulating programmed cell death in malignant cells. Synonyms: (3β)-Solanid-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside; α-Solanine; α-Solanin. CAS No. 20562-02-1. Molecular formula: C45H73NO15. Mole weight: 868.06.
Asomate
Asomate. Group: Biochemicals. Alternative Names: N, N-Di methyl carbamodithioic Acid Anhydrosulfide with Arsenotrithious Acid; Thioarsenious Acid (H3AsS3), Tris(anhydrosulfide) with Dimethyldithiocarbamic Acid (8CI); Asomate; TDDA; TTCA; Tris (di methyl dithiocarbamato) arsenic; Tris (di methyl dithiocarbamoyl) arsine. Grades: Highly Purified. CAS No. 3586-60-5. Pack Sizes: 1g. Molecular Formula: C9H18AsN3S6, Molecular Weight: 435.57. US Biological Life Sciences.
Worldwide
Asoprisnil
Asoprisnil is a selective progesterone receptor (PR) modulator developed for the treatment of progesterone sensitive myomata. Synonyms: J867; J-867; J 867; Asoprisnil; Asoprisnilum. 11beta-(4-((E)-(Hydroxyimino)methyl)phenyl)-17beta-methoxy-17-(methoxymethyl)estra-4,9-dien-3-one; (8S,11R,13S,14S,17S)-11-[4-[(E)-hydroxyiminomethyl]phenyl]-17-methoxy-17-(methoxymethyl)-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one. Grade: 98%. CAS No. 199396-76-4. Molecular formula: C28H35NO4. Mole weight: 449.58.
Asoprisnil ecamate
Asoprisnil ecamate is a selective progesterone receptor modulator potentially for the treatment of endometriosis. Synonyms: Benzaldehyde, 4-[(11β,17β)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4,9-dien-11-yl]-, 1-[O-[(ethylamino)carbonyl]oxime], [C(E)]-; J 956; (E)-4-((8S,11R,13S,14S,17S)-17-methoxy-17-(methoxymethyl)-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)benzaldehyde O-ethylcarbamoyl oxime; (11β,17β)-11-{4-[(E)-{[(Ethylcarbamoyl)oxy]imino}methyl]phenyl}-17-methoxy-17-(methoxymethyl)estra-4,9-dien-3-one. Grade: ≥95%. CAS No. 222732-94-7. Molecular formula: C31H40N2O5. Mole weight: 520.67.
Asoxime chloride
Asoxime chloride. Alternative Names: (((4-(iminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)pyridi;4'-carbamoyl-2-formyl-1,1'-(oxydimethylene)di-pyridinium-dichloride-2-oxime;hi6;hi-6;hi-6dichloride;hj6;pyridinium,1-(((4-(aminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino);pyridinium,4'-carbamoyl-2-formyl-1,1'-(oxydimethylene)di-,dichloride,2-oxi. CAS No. 34433-31-3. Purity: 98%. Product ID: ACM34433313. Molecular formula: C14H16Cl2N4O3. Mole weight: 359.21. IUPAC Name: ASOXIME CHLORIDE. Alfa Chemistry - ISO 9001:32057 Certified.
Asoxime chloride
Asoxime chloride. Group: Biochemicals. Alternative Names: 1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium dichloride; HI 6 chloride; HJ 6. Grades: Highly Purified. CAS No. 34433-31-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C14H16Cl2N4O3. US Biological Life Sciences.
Worldwide
Asoxime Chloride
Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Synonyms: 1[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]pyridinium Dichloride. Grade: > 95%. CAS No. 34433-31-3. Molecular formula: C14H16N4O3.2 Cl. Mole weight: 359.21.
Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Alternative Names: 1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium Dichloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Asoxime-d4 Chloride
Asoxime-d4 Chloride is a labelled Asoxime Chloride. Asoxime Chloride is a cholinesterase reactivator used in the treatment of organophosphate poisoning. Synonyms: 1[[[4-(Aminocarbonyl)pyridinio-d4]methoxy]methyl]-2-[(hydroxyimino)methyl]pyridinium Dichloride; HI 6-d4 Chloride; HJ 6-d4. Grade: > 95%. Molecular formula: C14H12N4O3D4·2Cl. Mole weight: 363.23.
ASP1126
ASP1126 is a selective and orally active agonist of sphingosine-1-phosphate (S1P), with EC50s of 7.12 and 517 nM for hS1P1 and hS1P3, respectively. ASP1126 can reduce the number of peripheral lymphocytes, naive T cells, central memory T cells and effector memory T cells in the peripheral blood, and has the potential to be used in clinical transplantation to improve safety profile. Synonyms: 1-[(7-{[4-(2,2,2-Trifluoroethoxy)-3-(trifluoromethyl)benzyl]oxy}-2H-chromen-3-yl)methyl]-4-piperidinecarboxylic acid hydrochloride (1:1); 4-Piperidinecarboxylic acid, 1-[[7-[[4-(2,2,2-trifluoroethoxy)-3-(trifluoromethyl)phenyl]methoxy]-2H-1-benzopyran-3-yl]methyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 1228580-11-7. Molecular formula: C26H26ClF6NO5. Mole weight: 581.93.
ASP-1645
ASP-1645 is a novel P2Y12 receptor antagonist using as an antiplatelet agent. Uses: An antiplatelet agent. Synonyms: ASP-1645; ASP 1645; ASP1645; UNII-M5SN288R8N; (2S)-2-((7-(cyclohexylamino)-1-cyclopentyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinyl)oxy)-Propanoic acid. Grade: 98%. CAS No. 1347392-70-4. Molecular formula: C23H29FN2O4. Mole weight: 416.49.
ASP2215 (Gilteritinib)
Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM). Group: Inhibitors. CAS No. 1254053-43-4. Pack Sizes: 5mg. Product ID: S7754. Formula: C29H44N8O3. Smiles: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5. Storage Conditions: 2 years -80 in solvent.
United States; Europe
ASP 2535
ASP-2535 has been found to be a GlyT1 inhibitor and brain penetrant. Synonyms: ASP-2535; ASP 2535; ASP2535; 4-[3-(1-Methylethyl)-5-(6-phenyl-3-pyridinyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole. Grade: ≥98% by HPLC. CAS No. 374886-51-8. Molecular formula: C22H18N6O. Mole weight: 382.42.
ASP 2535
ASP 2535. Group: Biochemicals. Grades: Purified. CAS No. 374886-51-8. Pack Sizes: 10mg. US Biological Life Sciences.