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| Product | Description | |
|---|---|---|
| Axitinib Impurity 29 | Axitinib Impurity 29. Uses: For analytical and research use. CAS No. 319472-78-1. Molecular formula: C7H4I2N2. Mole weight: 369.93. Catalog: APB319472781. |  |
| Axitinib Impurity 3 | Axitinib Impurity 3. Uses: For analytical and research use. Molecular formula: C30H24N6O2S2. Mole weight: 564.68. Catalog: APB06659. | |
| Axitinib Impurity 3 | Axitinib Impurity 3. Uses: For analytical and research use. Alternative Names: (E)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfinyl)benzamide. CAS No. 1347304-18-0. Molecular formula: C22H18N4O2S. Mole weight: 402.47. Catalog: APB1347304180. | |
| Axitinib Impurity 31 | Axitinib Impurity 31. Uses: For analytical and research use. CAS No. 886230-77-9. Molecular formula: C19H18IN3O. Mole weight: 431.28. Catalog: APB886230779. | |
| Axitinib Impurity 32 | Axitinib Impurity 32. Uses: For analytical and research use. CAS No. 2242852-05-5. Molecular formula: C19H19N3O. Mole weight: 305.38. Catalog: APB2242852055. | |
| Axitinib Impurity 33 | Axitinib Impurity 33. Uses: For analytical and research use. CAS No. 2527-66-4. Molecular formula: C8H7NOS. Mole weight: 165.21. Catalog: APB2527664. | |
| Axitinib Impurity 34 | Axitinib Impurity 34. Uses: For analytical and research use. CAS No. 319463-51-9. Molecular formula: C22H19ClN4OS. Mole weight: 422.93. Catalog: APB319463519. | |
| Axitinib Impurity 4 | Axitinib Impurity 4. Uses: For analytical and research use. Alternative Names: (E)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfonyl)benzamide. CAS No. 1348536-59-3. Molecular formula: C22H18N4O3S. Mole weight: 418.47. Catalog: APB1348536593. | |
| Axitinib Impurity 5 | Axitinib Impurity 5. Uses: For analytical and research use. Alternative Names: (Z)-2-(2-(6-((2-(methylcarbamoyl)phenyl)sulfinyl)-1H-indazol-3-yl)vinyl)pyridine 1-oxide. Molecular formula: C22H18N4O3S. Mole weight: 418.47. Catalog: APB02757. | |
| Axitinib Impurity 6 | Axitinib Impurity 6. Uses: For analytical and research use. Alternative Names: (Z)-2-(2-(6-((2-(methylcarbamoyl)phenyl)sulfonyl)-1H-indazol-3-yl)vinyl)pyridine 1-oxide. Molecular formula: C22H18N4O4S. Mole weight: 434.47. Catalog: APB02758. | |
| Axitinib Impurity 7 | Axitinib Impurity 7. Uses: For analytical and research use. Alternative Names: (E)-2-((1-acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide. CAS No. 1639137-80-6. Molecular formula: C24H20N4O2S. Mole weight: 428.51. Catalog: APB1639137806. | |
| Axitinib Impurity 8 | Axitinib Impurity 8. Uses: For analytical and research use. Alternative Names: (Z)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole. Molecular formula: C19H18N4O3. Mole weight: 350.37. Catalog: APB02756. | |
| Axitinib Impurity 9 | Axitinib Impurity 9. Uses: For analytical and research use. Alternative Names: N-methyl-2-((3-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 1443118-73-7. Molecular formula: C22H20N4OS. Mole weight: 388.49. Catalog: APB1443118737. | |
| Axitinib sulfone | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Alternative Names: Sulfonyl axitinib; (E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylsulfonyl)benzamide; N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide. Grades: ≥95%. CAS No. 1348536-59-3. Molecular formula: C22H18N4O3S. Mole weight: 418.47. |  |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide; Axitinib Impurity A. Grades: > 95%. CAS No. 1347304-18-0. Molecular formula: C22H18N4O2S. Mole weight: 402.48. | |
| AXKO-0046 | AXKO-0046, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor.AXKO-0046 has LDHB inhibitory activity with an EC50 value of 42 nM.AXKO-0046 can be used for the research of cancer metabolism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3103525-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147216. |  |
| Axltide | Axltide is based on mouse insulin receptor substrate 1 (amino acids 979-989). It is also a substrate for the kinases AXL, DDR2, MST1 and JAK2. Alternative Names: Axl / Insulin Receptor Substrate Peptide; H-Lys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Met-Gln-Ile-Gly-OH; L-lysyl-L-lysyl-L-seryl-L-arginyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-methionyl-L-threonyl-L-methionyl-L-glutaminyl-L-isoleucyl-glycine. Grades: ≥98%. CAS No. 143364-95-8. Molecular formula: C63H107N19O20S2. Mole weight: 1514.77. | |
| AY 9944 | AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 366-93-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107420. | |
| AY 9944 | Cholesterol synthesis inhibitor; inhibits both 7-dehydrocholesterol ?7-reductase and ?8,7-sterol isomerase. A sonic hedgehog inhibitor. Group: Biochemicals. Alternative Names: trans-N1, N4-Bis [ (2-chlorophenyl) methyl ] -1, 4-cyclohexane dimethanamine Hydrochloride; N, N'-Bis (o-chlorobenzyl)-trans-1, 4-cyclohexanebis (methylamine) Dihydrochloride. Grades: Highly Purified. CAS No. 366-93-8. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| AY 9944 dihydrochloride | AY 9944 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 366-93-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ayanin | Ayanin isolated from the rhizomes of Curcuma aromatica. Alternative Names: QUERCETIN 3,7,4'-TRIMETHYL ETHER;AYANIN;2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one;3',5-Dihydroxy-3,4',7-trimethoxyflavone; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one. Grades: 0.985. CAS No. 572-32-7. Molecular formula: C18H16O7. Mole weight: 344.3. | |
| AY-NH2 | AY-NH2. Group: Biochemicals. Grades: Purified. CAS No. 352017-71-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb / IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Alternative Names: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grades: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79. | |
| AZ0108 | AZ0108 is an orally bioavailable, PARP1,2,6 inhibitor that causes a multi-polar spindle phenotype at double digit nM concentrations. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. Alternative Names: (S)-4-((3-(3-(1,1-difluoroethyl)-6-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)phenyl)difluoromethyl)phthalazin-1(2H)-one; AZ0108; AZ-0108; AZ 0108. Grades: >98%. CAS No. 1825345-52-5. Molecular formula: C24H20F4N6O2. Mole weight: 500.45. | |
| AZ084 | AZ084 is a potent, selective, allosteric and oral active CCR8 allosteric antagonist, with a Ki of 0.9 nM. Has potential to treat asthma[1]. AZ084 restrains the formation of the immunologically tolerant pre-metastatic niche (PMN) and tumor cells metastasis in lung by downregulating Treg differentiation. AZ084 can be used in studies of asthma and cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 929300-19-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119217. | |
| AZ10606120 dihydrochloride | AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of about 10?nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 607378-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108669. | |
| AZ 12216052 | AZ 12216052. Group: Biochemicals. Grades: Purified. CAS No. 1290628-31-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AZ12601011 | AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748337-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122856. | |
| AZ12672857 | AZ12672857 is an orally active inhibitor of EphB4 (IC50=1.3 nM) and Src kinases. AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC50=2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC50=9 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 945396-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136895. | |
| AZ12799734 | AZ12799734 is a selective, orally active TGFBR1 kinase inhibitor with an IC50 of 47 nM. AZ12799734 is also a pan BMP and TGFβ inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1117684-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123900. | |
| AZ13824374 | AZ13824374 is a potent and selective ATAD2 bromodomain inhibitor (pIC50 of 6.9 in HCT116 cells). AZ13824374 disrupts chromatin interactions and gene transcription by binding to the acetyl-lysine binding site of the ATAD2 bromodomain. AZ13824374 has anticancer activity against breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3040082-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136521. | |
| AZ14170133 | AZ14170133 (SG 3932; AZ-0133) is a Drug-Linker Conjugates for ADC. AZ14170133 consists of the ADC cytotoxic payload topoisomerase 1 inhibitor and a linker. AZ14170133 can be used for synthesis of ADC AZD9592 (HY-171124) and AZD 8205 (HY-171689). AZ14170133 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SG 3932; AZ-0133. CAS No. 2495742-34-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145399. | |
| AZ1495 | AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2196204-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111101. | |
| AZ191 | AZ191 is a potent inhibitor that selectively inhibits DYRK1B with IC50 of 17 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1594092-37-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12277. | |
| AZ194 | AZ194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 μM). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241651-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145169. | |
| AZ20 | AZ20 is a potent and selective inhibitor of ATR with an IC50 of 5 nM, and has 8-fold selectivity against mTOR (IC50=38 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 1233339-22-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15557. | |
| AZ31 | AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC50 of <1.2 nM for ATM enzyme, and an IC50 of 46 nM for ATM in cell. AZ31 shows excellent selectivity over ATR (>500-fold) and excellent PIKK-family selectivity and pan-kinase selectivity. AZ31 is a potent radiosensitizer in vitro, it can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2088113-98-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-112198. | |
| AZ'3137 | AZ3137 is an orally active PROTAC-type androgen receptor (AR) degrader with a DC50 value of 22 nM. AZ3137 can degrade L702H mutant AR (DC50 of 92 nM). AZ'3137 can inhibit cell proliferation of LNCaP, with a GI50 value of 74 nM. AZ'3137 can inhibit AR signaling and tumor growth in prostate cancer mice (Pink: AR Ligand (HY-172954); Blue: CRBN ligand (HY-172955); Black: linker (HY-W262798); E3 Ligand+Linker: HY-172956)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2960179-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162702. | |
| AZ3146 | AZ3146 is a reasonably potent Mps1 and TTK inhibitor, with IC50 of 35 nM for Mps1Cat. Uses: Scientific research. Category: Signaling pathways. CAS No. 1124329-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14710. | |
| AZ32 | AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell. Uses: Scientific research. Category: Signaling pathways. CAS No. 2288709-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112305. | |
| AZ3246 | AZ3246 is an orally active and selective inhibitor of HPK1 with an IC50 of < 3 nM. AZ3246 induces IL-2 secretion in T cells with an EC50 of 90 nM. AZ3246 is a low-clearance antitumor compound that can be used for the study of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2893978-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173006. | |
| AZ3451 | AZ3451 is a potent protease-activated receptor-2 (PAR2) antagonist with IC50 of 23 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2100284-59-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112558. | |
| AZ505 | AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 μM) with potential anticancer activity. Alternative Names: AZ 505; AZ-505; N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)propanamide. Grades: 98%. CAS No. 1035227-43-0. Molecular formula: C29H38Cl2N4O4. Mole weight: 577.54. | |
| AZ505 | AZ505 is a potent and selective SMYD2 inhibitor with an IC50 of 0.12 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1035227-43-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15226. | |
| AZ506 | AZ506 is a potent SMYD2 inhibitor with an IC50 of 17 nM. AZ506 inhibits SMYD2 methyltransferase activity in cells, leading to a decrease in the SMYD2-mediated methylation signal[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2043321-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134828. | |
| AZ5104 | AZ5104 is a potent EGFR inhibitor and a derivative of AZD 9291. AZ5104 exhibits reduced selectivity against wild-type EGFR but five-fold potentcy compared to AZD 9291. Alternative Names: AZ-5104; AZ 5104; N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide. CAS No. 1421373-98-9. Molecular formula: C27H31N7O2. Mole weight: 485.592. | |
| AZ-5104 | AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421373-98-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0793. | |
| AZ5576 | AZ5576 is a potent and highly selective CDK9 inhibitor (IC50: <5 nM). AZ5576 inhibits the phosphorylation of RNA polymerase II at Ser2, thereby inhibiting transcriptional elongation. AZ5576 can be used for hematological Malignancy research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2751721-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143584. | |
| AZ6102 | AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50s of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50s of 2.0 μM, 0.5 μM, and >3 μM, for PARP1, PARP2, and PARP6, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1645286-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12975. | |
| AZ 628 | AZ 628 is a pan-Raf kinase inhibitor with IC50s of 105, 34 and 29 nM for B-Raf, B-RafV600E, and c-Raf-1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 878739-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11004. | |
| AZ'6421 | AZ'6421 acts as Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor alpha. AZ'6421 has a potent anti-tumour effect to inhibit the uncontrolled cellular proliferation which arises from malignant disease. AZ'6421 can be used for the research of cancer such as breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361115-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-135312. | |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Alternative Names: AZ-7371; AZ 7371; TBA-7371; DprE1-IN-1. Grades: 98%. CAS No. 1494675-86-3. Molecular formula: C18H21N5O3. Mole weight: 355.40. | |
| AZ7550 | AZ7550 is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421373-99-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0794. | |
| AZ7550 Mesylate | AZ7550 Mesylate, an active metabolite of AZD9291, inhibits the activity of IGF1R with an IC50 of 1.6 μM. Alternative Names: AZ7550 trimesylate salt; N-(4-Methoxy-5-{[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}phenyl)acrylamide methanesulfonate (1:3); 2-Propenamide, N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-, methanesulfonate (1:3). Grades: ≥98%. CAS No. 2319837-99-3. Molecular formula: C30H43N7O11S3. Mole weight: 773.90. | |
| AZ82 | AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449578-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12241. | |
| AZ8838 | AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2100285-41-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123617. | |
| AZ9482 | AZ9482 is a triple PARP1/2/6 inhibitor, with IC50 values of 1 nM, 1 nM and 640 nM for PARP1, PARP2 and PARP6, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1825345-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-119653. | |
| AZ'9567 | AZ'9567 is an orally active MAT2a inhibitor with a pIC50 of 9.1. AZ'9567 binds to MAT2a allosterically, reduces the synthesis of SAM, decreases SDMA levels, and exerts antiproliferative effects on MTAP-knockout cells. AZ'9567 depletes SAM, causes methionine accumulation in plasma and tissues, triggers adaptive disorders in one-carbon metabolism, transsulfuration metabolism and lipid metabolism, and induces oxidative stress, hepatic steatosis and lipid homeostasis imbalance. AZ'9567 can be used in studies related to MTAP-deficient/deleted cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056570-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162353. | |
| AZ960 | AZ960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 905586-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10411. | |
| AZ-960 | AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM. Alternative Names: (S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; 3-Pyridinecarbonitrile, 5-fluoro-2-(((1S)-1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)-; 5-Fluoro-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]nicotinonitrile. Grades: >98%. CAS No. 905586-69-8. Molecular formula: C18H16F2N6. Mole weight: 354.36. | |
| AZA | ~4-fold increase in efficiency with OSKM and promotes full reprogramming. Uses: Reprogramming. Alternative Names: 3'-Azido-2',3'-dideoxyadenosine; 66323-44-2; 3'-Azido-ddA; 3'-AzddAdo; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azidooxolan-2-yl]methanol; 3'-N3-ddA; [(2S,3S,5R)-5-(6-aminopurin-9-yl)-3-azido-tetrahydrofuran-2-yl]methanol; HG1022; 3'-Azido-2'-deoxyadenosine; CHEMBL590121; SCHEMBL18640424; DTXSID10216534; XDRZJDXXQHFAAE-RRKCRQDMSA-N; MFCD01630963; AKOS037644233; ((2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidotetrahydrofuran-2-yl)methanol; AS-49374; CS-0199753; A835421; 9-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-.beta.-D-erythro-pentofuranosyl)adenine; 9-(3'-Azido-2',3'-dideoxy-beta-D-erythro-pentofuranosyl)adenine; [(2S,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-azidooxolan-2-yl]methanol; 9H-purin-6-amine, 9-(3-azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-. Grades: ≥ 97%. CAS No. 66323-44-2. Molecular formula: C10H12N8O2. Mole weight: 276.26. | |
| AZA1 | AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rac1/Cdc42-IN-1. CAS No. 1071098-42-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-136383. | |
| Azabicyclo[2,2,1]hept-5-en-3-one | Azabicyclo[2,2,1]hept-5-en-3-one. CAS No. 49805-30-0. | |
| Aza-BODIPY | Aza-BODIPY. CAS No. 1195110-34-9. | |
| Azacitidine | Azacitidine is a pyrimidine nucleoside analogue of cytidine, classified as a nucleoside metabolic inhibitor with antineoplastic activity. It was initially FDA-approved in 2004 for adult myelodysplastic syndromes and subsequently approved for pediatric juvenile myelomonocytic leukemia in 2022. Applications: Azacitidine is indicated for adult patients with myelodysplastic syndrome subtypes including refractory anemia, refractory anemia with excess blasts, and chronic myelomonocytic leukemia. it is also indicated for pediatric patients aged one month and older with newly diagnosed juvenile myelomonocytic leukemia. Category: Anti-tumor apis. Synonyms: 5-azacytidine, Ladakamycin. CAS No. 320-67-2. Product ID: API0232320. Mole weight: 244.2. EINECS: 206-280-2. InChIKey: NMUSYJAQQFHJEW-KVTDHHQDSA-N. Appearance: White crystalline powder. |  |
| Azacitidine Impurity 1 | Azacitidine Impurity 1. Uses: For analytical and research use. Alternative Names: 4-amino-1-((2R,3R,4R,5R)-3-(((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one. Molecular formula: C13H20N4O9. Mole weight: 376.32. Catalog: APB03066. | |
| Azacitidine Impurity 1 | Azacitidine Impurity 1. Uses: For analytical and research use. CAS No. 645-92-1. Molecular formula: C3H5N5O. Mole weight: 127.11. Catalog: APB645921. | |
| Azacitidine Impurity 10 | Azacitidine Impurity 10. Uses: For analytical and research use. Alternative Names: N-((Z)-N'-(((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)carbamoyl)carbamimidoyl)formamide. Molecular formula: C8H14N4O6. Mole weight: 262.22. Catalog: APB03061. | |
| Azacitidine Impurity 11 | Azacitidine Impurity 11. Uses: For analytical and research use. Alternative Names: Azacitidine Impurity 11. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB03063. | |
| Azacitidine Impurity 12 | Azacitidine Impurity 12. Uses: For analytical and research use. Alternative Names: N-(Aminoiminomethyl)-N'-ß-D-ribofuranosylurea. CAS No. 2508-80-7. Molecular formula: C7H14N4O5. Mole weight: 234.21. Catalog: APB2508807. | |
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