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| Product | Description | |
|---|---|---|
| Asperlactone | Asperlactone is a biologically active polyketide metabolite produced mainly from Aspergillus westerdijkiae. Asperlactone is a nematicidal, an insecticidal, an antibacterial and an antifungal agent. Synonyms: 2(5H)-Furanone, 5-((1S)-1-hydroxyethyl)-3-((2S,3S)-3-methyloxiranyl)-, (5R)-; [2S-[2α[S*(R*)],3β]]-5-(1-hydroxyethyl)-3-(3-methyloxiranyl)-2(5H)-furanone. Grade: ≥98%. CAS No. 76375-62-7. Molecular formula: C9H12O4. Mole weight: 184.19. |  |
| Asperlactone (5- (1-Hydroxyethyl) -3- (2, 3-epoxypropyl) butenolide; (R)-5-((S)-1-Hydroxyethyl)-3-((2S,3S)-3-methyloxiran-2-yl)furan-2(5H)-one) | Antibiotic. Nematicidal, insecticidal, antibacterial and antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 76375-62-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Asperlicin | Asperlicin is a non-peptide cholecystokinin (Cholecystokinin, CCK) produced by Aspergillus alliaceus. It has the effect of antagonizing CCK. A and its derivatives are promising for the treatment of ulcers and pancreatic tumors. Synonyms: Asperlicin A. CAS No. 93413-04-8. Molecular formula: C31H29N5O4. Mole weight: 535.59. | |
| asperlicin C monooxygenase | The enzyme, characterized from the fungus Aspergillus alliaceus, contains an FAD cofactor. The enzyme inserts a hydroxyl group, leading to formation of a N-C bond that creates an additional cycle between the bicyclic indole and the tetracyclic core moieties, resulting in the heptacyclic asperlicin E. Group: Enzymes. Synonyms: AspB. Enzyme Commission Number: EC 1.14.13.216. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0818; asperlicin C monooxygenase; EC 1.14.13.216; AspB. Cat No: EXWM-0818. |  |
| Asperlin | Asperlin is an antibiotic produced by Aspergillus nidulans CMI 94163. Asperlin has anti-gram-positive bacteria, negative bacteria, mycobacterial activity, and inhibits KB cells. Synonyms: Asperlin; U 13933. Grade: >98%. CAS No. 30387-51-0. Molecular formula: C10H12O5. Mole weight: 212.20. | |
| Asperloxine A ((S)-4, 10-Dimethoxy-14, 15, 16, 16a-tetrahydro-benzo[e]oxepino[2', 3':4, 5]pyrimido[2, 1-c]pyrrolo[1, 2-a][1, 4]diazepine-6, 12-dione) | Natural benzodiazepine. Anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Asperosaponin IV | Asperosaponin IV. Group: Biochemicals. Alternative Names: Akebiasaponin D 4?-acetate; 4'-O-Acetyl-akebia saponin D. Grades: Plant Grade. CAS No. 126778-93-6. Pack Sizes: 10mg. Molecular Formula: C49H78O19, Molecular Weight: 971.131999999999. US Biological Life Sciences. | Worldwide |
| Asperosaponin VI | Asperosaponin VI. Group: Biochemicals. Alternative Names: Akebia saponin D. Grades: Plant Grade. CAS No. 39524-08-8. Pack Sizes: 20mg. Molecular Formula: C47H76O18, Molecular Weight: 929.096. US Biological Life Sciences. | Worldwide |
| Asperosaponin VI | Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Akebia saponin D. CAS No. 39524-08-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0265. |  |
| Asperphenamate | Asperphenamate is a fungal secondary metabolite isolated from Aspergillus flavipes. Asperphenamate has been found in a broad range of Pencillium and Aspergillus species and even in plants, as a product of endophytic fungi. Asperphenamate has weak antitumor activity. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). Asperphenamate is also used to synthesize N-Benzoyl-O-(N'-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth. Synonyms: (S)-N-Benzoyl-L-phenylalanine 2-(Benzoylamino)-3-phenylpropyl Ester; N-Benzoyl-phenylalanine 2-benzoylamino-3-phenylpropyl Ester; N-Benzoyl-L-phenylalaninol N-benzoyl-L-phenylalaninate; Anabellamide; Asjanin; NSC 306231; Auranamide. Grade: ≥95%. CAS No. 63631-36-7. Molecular formula: C32H30N2O4. Mole weight: 506.59. | |
| Aspersitin | Aspersitin is an antibiotic produced by Aspergillus parasiticus. It has anti-gram-positive and negative bacteria activity. CAS No. 86996-89-6. Molecular formula: C14H21NO4. Mole weight: 267.32. | |
| Asperuloside | Asperuloside is an iridoid monoterpenoid glycoside with anti-angiogenic, anti-inflammatory, and anti-obesity properties. Uses: Anti-inflammatory. Synonyms: [2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate. Grade: 98%. CAS No. 14259-45-1. Molecular formula: C18H22O11. Mole weight: 414.36. | |
| Asperuloside | Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 14259-45-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N1382. | |
| Asperuloside (Rubichloric acid) | Asperuloside (Rubichloric acid). Group: Biochemicals. Alternative Names: Rubichloric acid. Grades: Plant Grade. CAS No. 14259-45-1. Pack Sizes: 20mg. Molecular Formula: C18H22O11, Molecular Weight: 414.363. US Biological Life Sciences. | Worldwide |
| Asperulosidic Acid | Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities[1].ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25368-11-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6246. | |
| Asperulosidic Acid | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 25368-11-0. Pack Sizes: 10mg, 20mg. US Biological Life Sciences. | Worldwide |
| Asphaltum (technical grade) | Asphaltum (technical grade). Alternative Names: Bitumen. CAS No. 8052-42-4. Purity: Tech. Product ID: ACM8052424-1. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Aspicilin | It is obtained from the lichens Aspicilia calcarea and A. gibbosa. Synonyms: (-)-Aspicillin; (5R,6S,7R,18S,E)-5,6,7-trihydroxy-18-methyloxacyclooctadec-3-en-2-one; (3E,5R,6S,7R,18S)-5,6,7-Trihydroxy-18-methyloxacyclooctadeca-3-en-2-one; Oxacyclooctadec-3-en-2-one, 5,6,7-trihydroxy-18-methyl-, (3E,5R,6S,7R,18S)-. Grade: 99%. CAS No. 52461-05-9. Molecular formula: C18H32O5. Mole weight: 328.44. | |
| Aspiculamycin | Aspiculamycin is a nucleoside peptide antibiotic produced by Streptomyces toyocaensis var. aspiculamyceticus. It has weak anti-Gram-positive bacteria, negative bacteria, mycobacteria and mycoplasma activity, and has the effect of repelling worms, nematodes and killing worms. Synonyms: Aspiculamycin; Quingfengmycin; Gougerotin. Molecular formula: C19H30O10N8. Mole weight: 530.49. | |
| Aspinonene (6,7-Epoxy-5-hydroxymethyl-3-octen-2,5-diol, (2R,5S,E)-2-((2R,3S)-3-Methyloxiran-2-yl)hex-3-ene-1,2,5-triol) | Multifunctional fungal secondary metabolite. Related to aspyrone. Group: Biochemicals. Grades: Highly Purified. CAS No. 157676-96-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aspirin | Aspirin. Uses: For analytical and research use. Alternative Names: Enterophen, Doril, Miniasal, Acetosalin, Asagran, Aspirin Protect 300, Bialpirina, Acenterine, Acetilum acidulatum, Adiro, Coricidin D, Globentyl, Aspirin-Direkt, Micristin, Benaspir, Claradin, Acetisal, Aspro Clear, Enterosarine, Neuronika, Rhodine NC RP, Astrix, Acetylsalicylic acid, Entrophen, Endydol, Acetosalic acid, Acesan, Acetylin, Rhodine (7CI), Globoid, Acetard, O-Acetylsalicylic acid, T. CAS No. 50-78-2. Molecular formula: C9H8O4. Mole weight: 180.16. IUPAC Name: 2-acetyloxybenzoic acid. Catalog: APS50782A. |  |
| Aspirin | Aspirin is a salicylate and irreversible COX1 and COX2 inhibitor. It can be used for the treatment of fever, rheumatism, nerve, muscle, joint pain, soft tissue inflammation and gout in animals. Synonyms: Acetylsalicylic acid. Grade: 99.5%. CAS No. 50-78-2. Molecular formula: C9H8O4. Mole weight: 180.16. | |
| Aspirin | Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Acetylsalicylic acid; ASA. CAS No. 50-78-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-14654. | |
| Aspirin (Acetyl Salicylic Acid) | Aspirin (Acetyl Salicylic Acid). Uses: For analytical and research use. CAS No. 50-78-2. Mole weight: 180.16. EC Number: 200-064-1. Catalog: AP50782-B. | |
| Aspirin Impurity | A metabolite of Acetylsalicylic Acid. Synonyms: 2-(2,4-Dihydroxybenzoyl)benzoic Acid. Grade: > 95%. CAS No. 2513-33-9. Molecular formula: C14H10O5. Mole weight: 258.23. | |
| Aspirin Impurity 1 | Aspirin Impurity 1. Uses: For analytical and research use. Molecular formula: C16H12O6. Mole weight: 300.27. Catalog: APB06604. | |
| Aspirin Impurity 11 | Aspirin Impurity 11. Uses: For analytical and research use. CAS No. 85531-16-4. Molecular formula: C23H16O8. Mole weight: 420.37. Catalog: APB85531164. | |
| Aspirin Impurity 16 | Aspirin Impurity 16. Uses: For analytical and research use. CAS No. 24719-72-0. Molecular formula: C15H16O10. Mole weight: 356.28. Catalog: APB24719720. | |
| Aspirin Impurity 18 | Aspirin Impurity 18. Uses: For analytical and research use. Molecular formula: C17H27N3O6. Mole weight: 369.42. Catalog: APB06605. | |
| Aspirin Impurity 19 | Aspirin Impurity 19. Uses: For analytical and research use. CAS No. 85531-25-5. Molecular formula: C15H12O5. Mole weight: 272.26. Catalog: APB85531255. | |
| Aspirin Impurity 2 | Aspirin Impurity 2. Uses: For analytical and research use. CAS No. 318515-20-7. Molecular formula: C12H10N2O3. Mole weight: 230.22. Catalog: APB318515207. | |
| Aspirin Impurity 3 | Aspirin Impurity 3. Uses: For analytical and research use. CAS No. 15540-79-1. Molecular formula: C8H7NO5. Mole weight: 197.15. Catalog: APB15540791. | |
| Aspirin Impurity 36 | Aspirin Impurity 36. Uses: For analytical and research use. CAS No. 7695-70-7. Molecular formula: C13H14O9. Mole weight: 314.25. Catalog: APB7695707. | |
| Aspirin Impurity 4 | Aspirin Impurity 4. Uses: For analytical and research use. CAS No. 2513-33-9. Molecular formula: C14H10O5. Mole weight: 258.23. Catalog: APB2513339. | |
| Aspirin Impurity A-D4 (Aspirin Impurity 12) | Aspirin Impurity A-D4 (Aspirin Impurity 12). Uses: For analytical and research use. CAS No. 152404-47-2. Molecular formula: C7H2D4O3. Mole weight: 142.15. Catalog: APB152404472. | |
| Aspirin Impurity D | Aspirin Impurity D. Uses: For analytical and research use. CAS No. 530-75-6. Mole weight: 300.26. Catalog: AP530756. | |
| Aspirin Impurity E | Aspirin Impurity E. Uses: For analytical and research use. CAS No. 552-94-3. Mole weight: 258.23. EC Number: 209-027-4. Catalog: AP552943-A. | |
| Aspirin Impurity F | Aspirin Impurity F. Uses: For analytical and research use. CAS No. 1466-82-6. Mole weight: 342.30. EC Number: 215-987-5. Catalog: AP1466826. | |
| Aspirin-L-argininie | Aspirin-L-argininie. Group: Biochemicals. Grades: Highly Purified. CAS No. 37466-21-0. Pack Sizes: 500mg, 1000mg. Molecular Formula: C15H22N4O6, Molecular Weight: 354.36. US Biological Life Sciences. | Worldwide |
| Aspirin (Standard) | Aspirin (Standard) is the analytical standard of Aspirin. This product is intended for research and analytical applications. Aspirin (Acetylsalicylic acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetylsalicylic acid(Standard); ASA (Standard). CAS No. 50-78-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-14654R. | |
| AspLE I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. GCG↑C C↓GCG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Arthrobacter species LE3860. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1025EN. | |
| Asp-Leu | Alpha-Asp-Leu is a dipeptide formed from aspartic acid and leucine. Synonyms: H-ASP-LEU-OH; L-ASPARTIC ACID-L-LEUCINE; Asp-Leu-OH; L-Asp-L-Leu-OH; N-L-α-Aspartyl-L-leucine. Grade: ≥97% by HPLC. CAS No. 3062-14-4. Molecular formula: C10H18N2O5. Mole weight: 246.26. | |
| Aspochalasin D | Aspochalasin D is a potent inhibitor of mammalian tumor cell lines, first isolated from Aspergillus microcysticus. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D was found that it can strongly induce the formation of actin-containing rodlets in the cytoplasm of treated fibroblasts. Synonyms: 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-. Grade: ≥95%. CAS No. 71968-02-0. Molecular formula: C24H35NO4. Mole weight: 401.54. | |
| Aspochalasine A | Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Aspochalasine A has anti-bacterial and fungal activity. Molecular formula: C24H33NO4. Mole weight: 399.52. | |
| Aspochalasine E | Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Molecular formula: C24H33NO3. Mole weight: 383.52. | |
| Aspochalasin I | Cytotoxic. Melanogenesis inhibitor without cytotoxicity. Group: Biochemicals. Alternative Names: (3E, 5R, 6S, 9E, 10aS, 13S, 13aS, 14S, 16aR)-6, 7, 8, 10a, 13, 13a, 14, 15-Octahydro-5, 6-dihydroxy-9, 12, 13-trimethyl-14-(2-methylpropyl)-2H-oxacyclododecino[2, 3-d]isoindole-2, 16(5H)-dione. Grades: Highly Purified. CAS No. 670225-69-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H35NO5, Molecular Weight: ~417.5. US Biological Life Sciences. | Worldwide |
| Aspochalasin M | Aspochalasin M is a fungal metabolite originally isolated from S. elegans. It can inhibit the growth of HL-60 cells (IC50 = 20 μM). Synonyms: Aspochalasin M; 1173040-34-0; (1S,5S,9Z,11S,14S,15R,16S)-5-hydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-9,12-diene-2,6,18-trione; (3S,3aR,4S,6aS,7E,12S,15aS)-3,3a,4,6a,9,10,13,14-octahydro-12-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,11,15(2H,12H)-trione. Grade: >95%. CAS No. 1173040-34-0. Molecular formula: C24H35NO4. Mole weight: 401.54. | |
| Aspochracin | Aspochracin is a cyclic tripeptide isolated from Aspergillus first. Aspochracin is toxic to caught worms (LD50 = 100 μg/g) and silkworms. Grade: >95% by HPLC. CAS No. 22029-09-0. Molecular formula: C23H36N4O4. Mole weight: 432.56. | |
| Aspoxicillin | Aspoxicillin is a semi-synthetic penicillin prepared from 6-aminopenicillanic acid (6-APA) or Amoxicillin. It has a broad antibacterial spectrum and has an effect on Pseudomonas aeruginosa. Synonyms: Aspoxicilina; Aspoxicilline; Aspoxicillinum. Grade: >98%. CAS No. 63358-49-6. Molecular formula: C21H27N5O7S. Mole weight: 493.53. | |
| Asp-Phe | A metabolite of Aspartame. Synonyms: L-Aspartyl-L-phenylalanine. Grade: >98%. CAS No. 13433-09-5. Molecular formula: C13H16N2O5. Mole weight: 280.28. | |
| AspS9 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑GNCC CCNG↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Arthrobacter species S9. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1026EN. | |
| Aspterric acid | Antibiotic. Pollen growth and development inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 67309-95-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| aspulvinone dimethylallyltransferase | This enzyme will also use as acceptor aspulvinone G, a hydroxylated derivative of the complex phenolic pigment aspulvinone E. Group: Enzymes. Synonyms: dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase. Enzyme Commission Number: EC 2.5.1.35. CAS No. 67584-68-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2772; aspulvinone dimethylallyltransferase; EC 2.5.1.35; 67584-68-3; dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase. Cat No: EXWM-2772. | |
| Aspulvinone O | Aspulvinone O is a fungal metabolite originally isolated from P. variotti and has antioxidant and anticancer activities. It inhibits aspartate transaminase 1 (GOT1, Kd=3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM). Aspulvinone O (2.5 and 5 mg/kg) reduces tumor growth in an SW1990 mouse xenograft model because it reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Synonyms: 914071-54-8; 3-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]methylene]-2(5H)-furanone(5Z)-3-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methylidene]furan-2-one; Aspulvinone OMEGxm0_000073. Grade: >98%. CAS No. 914071-54-8. Molecular formula: C27H28O6. Mole weight: 448.51. | |
| Aspyrone ((5S,6R)-5-Hydroxy-6-methyl-3-((2S,3S)-3-methyl-oxiran-2-yl)-5,6-dihydro-2H-pyran-2-one) | Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene. Group: Biochemicals. Grades: Highly Purified. CAS No. 17398-00-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C9H12O4. US Biological Life Sciences. | Worldwide |
| ASR-490 | ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2690312-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144899. | |
| Assay Buffer (10X) | Assay Buffer (10X). Group: Molecular Biology. Alternative Names: For Human Topoisomerase I, Cat#T8065A. US Biological Life Sciences. | Worldwide |
| assemblin | Involved in the breakdown of the scaffold protein during the late stages of assembly of the herpes-virus virion. Inhibited by diisopropyl fluorophosphate. Type example of peptidase family S21. Catalytic residues are His, Ser, His, a combination not known for any other peptidase, and the protein fold also is unique. Known from herpes viruses of several types, cytomegalovirus, Epstein-Barr virus and human herpesvirus 3. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.97. CAS No. 139691-88-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4189; assemblin; EC 3.4.21.97; 139691-88-6. Cat No: EXWM-4189. | |
| assimilatory sulfite reductase (ferredoxin) | An iron protein. The enzyme participates in sulfate assimilation. While it is usually found in cyanobacteria, plants and algae, it has also been reported in bacteria. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.1.2, assimilatory sulfite reductase (NADPH). Group: Enzymes. Synonyms: ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Enzyme Commission Number: EC 1.8.7.1. CAS No. 37256-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1680; assimilatory sulfite reductase (ferredoxin); EC 1.8.7.1; 37256-50-1; ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Cat No: EXWM-1680. | |
| assimilatory sulfite reductase (NADPH) | Contains siroheme, [4Fe-4S] cluster, FAD and FMN. The enzyme, which catalyses the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin). Group: Enzymes. Synonyms: sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Enzyme Commission Number: EC 1.8.1.2. CAS No. 9029-35-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1646; assimilatory sulfite reductase (NADPH); EC 1.8.1.2; 9029-35-0; sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Cat No: EXWM-1646. | |
| AST-1306 | AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor. Group: Biochemicals. Alternative Names: N- [4- [ [3-Chloro-4- [ (3-fluorobenzyl) oxy] phenyl] amino] quinazolin-6-yl] acrylamide; N-[4-[[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide; ALS1306; AST 1306; AST 6. Grades: Highly Purified. CAS No. 897383-62-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| AST-1306 | AST-1306 functions as an irreversible inhibitor, most likely through covalent interaction with Cys797 and Cys805 in the catalytic domains of EGFR and ErbB2, respectively. It inactivated pathways downstream of these receptors and thereby inhibited the proliferation of a panel of cancer cell lines. It blocks phosphorylation of EGFR and also prevents downstream pathways. It also dose-dependently inhibits EGF-induced EGFR phosphorylation in the A549 cancer cell line. Synonyms: AST-1306; AST 1306; AST1306. Grade: >98%. CAS No. 897383-62-9. Molecular formula: C24H18ClFN4O2. Mole weight: 448.88. | |
| AST-1306 tosylate | AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases. Synonyms: AST-6; AST 6; AST6. Grade: >98%. CAS No. 1050500-29-2. Molecular formula: C24H18ClFN4O2,C7H8O3S. Mole weight: 621.08. | |
| AST 487 | AST487 is a Ret kinase inhibitor/FLT3 inhibitor, which displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. It induced a dose-dependent growth inhibition of xenografts of NIH3T3 cells expressing oncogenic RET, and of the MTC cell line TT in nude mice.It also inhibited calcitonin gene expression in vitro in TT cells, in part, through decreased gene transcription. Synonyms: NVP-AST 487; NVPAST487; AST 487; AST487; AST-487. Grade: >98%. CAS No. 630124-46-8. Molecular formula: C26H30F3N7O2. Mole weight: 529.56. | |
| AST 487 | AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NVP-AST 487. CAS No. 630124-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15002. | |
| AST 487 | AST 487 Inhibitor. Uses: Scientific use. Product Category: T4053. CAS No. 630124-46-8. |  |
| AST-487 | Potent RET kinase inhibitor. AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. Group: Biochemicals. Grades: Highly Purified. CAS No. 630124-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| AST5902 | AST5902, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-; N-[5-[[4-(1-Methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide; AST 5902; AST-5902. Grade: ≥95%. CAS No. 2412155-74-7. Molecular formula: C27H29F3N8O2. Mole weight: 554.57. | |
| AST5902 mesylate | AST5902 mesylate, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-, compd. with methanesulfonate (1:1); AST 5902 mesylate; AST-5902 mesylate; N-(2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate. Grade: ≥95%. CAS No. 2412155-75-8. Molecular formula: C27H29F3N8O2.CH4O3S. Mole weight: 650.67. | |
| AST5902 trimesylate | AST5902 trimesylate, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: N-[5-{[4-(1-Methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]acrylamide methanesulfonate (1:3); 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-, methanesulfonate (1:3). Grade: ≥98%. CAS No. 2929417-90-1. Molecular formula: C30H41F3N8O11S3. Mole weight: 842.88. | |
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