A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Aspulvinone O is a fungal metabolite originally isolated from P. variotti and has antioxidant and anticancer activities. It inhibits aspartate transaminase 1 (GOT1, Kd=3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM). Aspulvinone O (2.5 and 5 mg/kg) reduces tumor growth in an SW1990 mouse xenograft model because it reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Synonyms: 914071-54-8; 3-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]methylene]-2(5H)-furanone(5Z)-3-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methylidene]furan-2-one; Aspulvinone OMEGxm0_000073. Grade: >98%. CAS No. 914071-54-8. Molecular formula: C27H28O6. Mole weight: 448.51.
Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene. Group: Biochemicals. Grades: Highly Purified. CAS No. 17398-00-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C9H12O4. US Biological Life Sciences.
Worldwide
ASS234
ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC 50 s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC 50 s of 350 nM and 460 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334106-34-1. Pack Sizes: 5 mg. Product ID: HY-121072.
Assay Buffer (10X)
Assay Buffer (10X). Group: Molecular Biology. Alternative Names: For Human Topoisomerase I, Cat#T8065A. US Biological Life Sciences.
Worldwide
assemblin
Involved in the breakdown of the scaffold protein during the late stages of assembly of the herpes-virus virion. Inhibited by diisopropyl fluorophosphate. Type example of peptidase family S21. Catalytic residues are His, Ser, His, a combination not known for any other peptidase, and the protein fold also is unique. Known from herpes viruses of several types, cytomegalovirus, Epstein-Barr virus and human herpesvirus 3. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.97. CAS No. 139691-88-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4189; assemblin; EC 3.4.21.97; 139691-88-6. Cat No: EXWM-4189.
assimilatory sulfite reductase (ferredoxin)
An iron protein. The enzyme participates in sulfate assimilation. While it is usually found in cyanobacteria, plants and algae, it has also been reported in bacteria. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.1.2, assimilatory sulfite reductase (NADPH). Group: Enzymes. Synonyms: ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Enzyme Commission Number: EC 1.8.7.1. CAS No. 37256-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1680; assimilatory sulfite reductase (ferredoxin); EC 1.8.7.1; 37256-50-1; ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Cat No: EXWM-1680.
assimilatory sulfite reductase (NADPH)
Contains siroheme, [4Fe-4S] cluster, FAD and FMN. The enzyme, which catalyses the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin). Group: Enzymes. Synonyms: sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Enzyme Commission Number: EC 1.8.1.2. CAS No. 9029-35-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1646; assimilatory sulfite reductase (NADPH); EC 1.8.1.2; 9029-35-0; sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Cat No: EXWM-1646.
AST-1306
AST-1306 functions as an irreversible inhibitor, most likely through covalent interaction with Cys797 and Cys805 in the catalytic domains of EGFR and ErbB2, respectively. It inactivated pathways downstream of these receptors and thereby inhibited the proliferation of a panel of cancer cell lines. It blocks phosphorylation of EGFR and also prevents downstream pathways. It also dose-dependently inhibits EGF-induced EGFR phosphorylation in the A549 cancer cell line. Synonyms: AST-1306; AST 1306; AST1306. Grade: >98%. CAS No. 897383-62-9. Molecular formula: C24H18ClFN4O2. Mole weight: 448.88.
AST-1306
AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor. Group: Biochemicals. Alternative Names: N- [4- [ [3-Chloro-4- [ (3-fluorobenzyl) oxy] phenyl] amino] quinazolin-6-yl] acrylamide; N-[4-[[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide; ALS1306; AST 1306; AST 6. Grades: Highly Purified. CAS No. 897383-62-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AST-1306 tosylate
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases. Synonyms: AST-6; AST 6; AST6. Grade: >98%. CAS No. 1050500-29-2. Molecular formula: C24H18ClFN4O2,C7H8O3S. Mole weight: 621.08.
AST487 is a Ret kinase inhibitor/FLT3 inhibitor, which displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. It induced a dose-dependent growth inhibition of xenografts of NIH3T3 cells expressing oncogenic RET, and of the MTC cell line TT in nude mice.It also inhibited calcitonin gene expression in vitro in TT cells, in part, through decreased gene transcription. Synonyms: NVP-AST 487; NVPAST487; AST 487; AST487; AST-487. Grade: >98%. CAS No. 630124-46-8. Molecular formula: C26H30F3N7O2. Mole weight: 529.56.
AST 487
AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-AST 487. CAS No. 630124-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15002.
AST-487
Potent RET kinase inhibitor. AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. Group: Biochemicals. Grades: Highly Purified. CAS No. 630124-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
AST5902
AST5902 is the active metabolite of Firmonertinib (HY-112870) (EGFR inhibitor). AST5902 has antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2412155-74-7. Pack Sizes: 1 mg. Product ID: HY-138627.
AST5902
AST5902, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-; N-[5-[[4-(1-Methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide; AST 5902; AST-5902. Grade: ≥95%. CAS No. 2412155-74-7. Molecular formula: C27H29F3N8O2. Mole weight: 554.57.
AST5902 mesylate
AST5902 mesylate, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-, compd. with methanesulfonate (1:1); AST 5902 mesylate; AST-5902 mesylate; N-(2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate. Grade: ≥95%. CAS No. 2412155-75-8. Molecular formula: C27H29F3N8O2.CH4O3S. Mole weight: 650.67.
AST5902 trimesylate
AST5902 trimesylate, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: N-[5-{[4-(1-Methyl-1H-indol-3-yl)-2-pyrimidinyl]amino}-2-{methyl[2-(methylamino)ethyl]amino}-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]acrylamide methanesulfonate (1:3); 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-, methanesulfonate (1:3). Grade: ≥98%. CAS No. 2929417-90-1. Molecular formula: C30H41F3N8O11S3. Mole weight: 842.88.
Astacene
Astacene. Group: Biochemicals. Alternative Names: 3,3'-Dihydroxy-2,3,2',3'-tetradehydro-b,b-carotene-4,4'-dione. Grades: Highly Purified. CAS No. 514-76-1. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Astacidin
Astacidin is an antimicrobial peptide produced by Procambarus clarkii (freshwater crayfish Pacifastacus leniusculus). It encodes a peptide of 43 amino acids, with a signal peptide of 23 amino acids. The mature peptide contains 20 amino acids, among which four are proline/arginine amino acids. The synthetic mature peptide has inhibitory effects on both Gram-positive and gram-negative bacteria and has the ability to bind bacterial cell wall components, including peptidoglycan, lipopolysaccharide and lipophoteicic acid. Synonyms: PcAst; Met-Arg-Leu-Leu-His-Leu-Leu-Leu-Ser-Val-Ala-Leu-Val-Ala-Leu-Met-Ala-Ala-Val-Pro-Ser-Gln-Ala-Ser-Asn-Gly-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ser-Tyr-Arg-Pro-Gly-Lys. Grade: >98%.
Astacidin 1
Astacidin 1 is an antimicrobial peptide produced by Pacifastacus leniusculus (Procambarus clarkii, Red swamp freshwater crayfish). It exhibits antifungal activity against Candida albicans, Trichosporon beigelii, Malassezia furfur and Trichophyton rubrum. Synonyms: H-Phe-Lys-Val-Gln-Asn-Gln-His-Gly-Gln-Val-Val-Lys-Ile-Phe-His-His-OH; L-phenylalanyl-L-lysyl-L-valyl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-histidylglycyl-L-glutaminyl-L-valyl-L-valyl-L-lysyl-L-isoleucyl-L-phenylalanyl-L-histidyl-L-histidine. Grade: >97%. Molecular formula: C90H136N28O21. Mole weight: 1946.24.
Astacidin 2
Astacidin 2 is an antimicrobial peptide produced by Pacifastacus leniusculus (freshwater signal crayfish). It has a broad range of antibacterial activity against gram-positive and gram-negative bacteria. Synonyms: Arg-Pro-Arg-Pro-Asn-Tyr-Arg-Pro-Arg-Pro-Ile-Tyr-Arg-Pro-NH2. Grade: ≥95%. Molecular formula: C83H133N31O17. Mole weight: 1837.18.
astacin
A 22.6 kDa digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis. Type example of peptidase family M12. Group: Enzymes. Synonyms: Astacus proteinase; crayfish small-molecule proteinase. Enzyme Commission Number: EC 3.4.24.21. CAS No. 143179-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4302; astacin; EC 3.4.24.21; 143179-21-9; Astacus proteinase; crayfish small-molecule proteinase. Cat No: EXWM-4302.
Astaxanthin
1g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Stains & Indicators. Formula: C40H52O4. CAS No. 472-61-7. Prepack ID 38028884-1g. Molecular Weight 596.84. See USA prepack pricing.
Astaxanthin
Astaxanthin is a carotenoid pigment found mostly in animal organisms, but also occurring in plants. It is thought to be the precursor of astacin. It is a potent lipid-soluble antioxidant. It has broad application prospects in health products, medicine, cosmetics, food additives and aquaculture. Astaxanthin is a natural antioxidant with the strongest antioxidant and anti-aging ability in nature, and its antioxidant capacity is much higher than VE and β-carotene. It significantly enhances mitochondrial activity required for cell recombination and effectively protects the skin from UVA, UVB and blue light damage. Uses: Ingredient of health care products. Synonyms: Ovoester; Astaxanthine; (3S,3'S)-Astaxanthin; All-trans-Astaxanthin; 3,3'-Dihydroxy-β,β-carotene-4,4'-dione; 3,3'-Dhydroxy-4,4'-diketo-β-carotene; trans-Astaxanthin; (3S,3'S)-all-trans-Astaxanthin; (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone). Grade: 95% by HPLC. CAS No. 472-61-7. Molecular formula: C40H52O4. Mole weight: 596.84.
Astaxanthin is a functional, lipid-soluble and water-soluble pigment, which is widely used in aquaculture, food, cosmetics and other fields. Alternative Names: 3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE;3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE;3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE. CAS No. 472-61-7. Product ID: PIPE-0013. Molecular formula: C40H52O4. Mole weight: 596.85. SMILES: CC1=C(C(C[C@@H](C1=O)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)/C)/C. Appearance: Powder. Category: Natural Extract.
Astaxanthin
Astaxanthin. Group: Others. Purity: 1%, 2%, 3%, 5%, 10% astaxanthin. Appearance: Dark red oil or powder. Astaxanthin. Cat No: EXTC-129.
Astaxanthin
Astaxanthin - Product ID: NST-10-191. Category: Terpenes. Alternative Names: Astaxanthin, Natupink, BioAstin, Carophyll Pink, Lucantin Pink, trans-Astaxanthin. Purity: 5%. Test method: UV. CAS No. 472-61-7. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Pink to red to violet-brown to dark purple powder. Molecular formula: C40H52O4. Mole weight: 596.84. Storage: +2 +8 °C.
Astaxanthin
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis , impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 472-61-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2163.
Astaxanthin. Synonyms: 3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE;3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE;3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE;ASTAXANTHIN;AXN;Astazine 5%;(3S,3S)-3,3-Dihydroxy-.beta.. beta.-carotene-4,4-dione;HAEMATOCOCCUS PLUVIALIS. CAS No. 472-61-7. Pack Sizes: 1 kg. Product ID: CDF4-0145. Molecular formula: C40H52O4. Category: Nutrients. Product Keywords: Food Ingredients; Nutrients; Astaxanthin; CDF4-0145; 472-61-7; C40H52O4; 207-451-4; 472-61-7. Purity: 0.99. Color: pink to very dark purple. EC Number: 207-451-4. Physical State: Powder. Solubility: DMSO: soluble1mg/mL (warmed). Storage: -20°C. Boiling Point: 568.55°C (rough estimate). Melting Point: 215-216 °C. Density: 0.9980 (rough estimate). Product Description: all-trans-Astaxanthin is a ketocarotenoid, most commonly identified in marine and aquatic animals, including krill, wild salmon, rainbow trout, microalgae, shells of lobster, shrimp, seafood products, etc. It is biologically known as a vitamin A precursor, and exhibits strong antioxidant property, much higher compared to vitamin E and β-carotene. Its role in food and the medicinal industry is also well-defined.
Astaxanthin 2%
Astaxanthin 2%.
CA, FL & NJ
Astaxanthin (crystalline)
Astaxanthin (crystalline). CAS No: 472-61-7
Sarchem Laboratories New Jersey NJ
Astaxanthin dipalmitate
Astaxanthin dipalmitate. Group: Biochemicals. Alternative Names: (3RS,3'RS)-3,3'-Dihexadecanoyloxy-b,b-carotene-4,4'-dioneAstaxanthin dipalmitate. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Astaxanthin esters from Haematococcus pluvialis
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Astaxanthin microencapsulated powder
Astaxanthin microencapsulated powder. Synonyms: 3, 3'-DIHYDROXY-B, B-CAROTENE-4, 4'-DIONE;3, 3-DIHYDROXY-B, B-CAROTENE-4, 4-DIONE;3, 3'-DIHYDROXY-BETA, BETA-CAROTENE-4, 4'Chemicalbook-DIONE;ASTAXANTHIN;AXN;Astazine5%;(3S, 3S)-3, 3-Dihydroxy-.beta.. beta.-carotene-4,4-dione;HAEMATOCOCCUSPLUVIALIS. Product ID: CDF4-0194. Molecular formula: NA. Category: Antioxidant; nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0194; Astaxanthin microencapsulated powder; Antioxidant; nutrient supplements. Appearance: pink to very dark purple powder. Chemical Name: 3, 3'-DIHYDROXY-B, B-CAROTENE-4, 4'-DIONE;3, 3-DIHYDROXY-B, B-CAROTENE-4, 4-DIONE;3, 3'-DIHYDROXY-BETA, BETA-CAROTENE-4, 4'Chemicalbook-DIONE;ASTAXANTHIN;AXN;Astazine5%;(3S, 3S)-3, 3-Dihydroxy-.beta.. beta.-carotene-4,4-dione;HAEMATOCOCCUSPLUVIALIS. Color: pink to very dark purple. Physical State: powder. Source and Preparation: Shrimp, crab, fish. Solubility: DMSO: soluble1mg/mL (warmed). Storage: -20°C. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. Boiling Point: 568.55°C (rough estimate). Melting Point: 215-216 °C. Density: 0.9980 (rough estimate).
Astaxanthin monopalmitate
Astaxanthin monopalmitate. Group: Biochemicals. Alternative Names: (3RS,3'RS)-3-Hexadecanoyloxy-b,b-carotene-4,4'-dione. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Astaxanthin (synthetic)
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Astechrome is an antibiotic produced by Aspergillus terreus (IFO 6123). It has weak antibacterial activity. Molecular formula: (C20H22N3O3)3Fe. Mole weight: 1113.09.
Astegolimab
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2 , the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MSTT 1041A; RG 6149. CAS No. 2173054-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99444.
Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC 50 of 4 nM. Astemizole also shows potent hERG K + channel blocking activity with an IC 50 of 0.9 nM. Astemizole has antipruritic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 43512. CAS No. 68844-77-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12532.
Astemizole
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Astemizole
Nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic. Group: Biochemicals. Alternative Names: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan; Hismanal; Histamen; Paralergin; R 42512; R 43512; Retolen; Waruzol. Grades: Highly Purified. CAS No. 68844-77-9. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Astemizole
Astemizole is a potent and orally active nonsedating-type histamine H1 receptor antagonist with IC50 value of 4 nM. It competitively binds to histamine H1 receptor sites in the uterus, gastrointestinal tract, bronchial muscle and blood vessels. It suppresses the formation of edema and pruritus caused by histamine. It has antipruritic and anticholinergic effects. It is also a potent blocker of ether-a-go-go-related gene (ERG) potassium channel blocker with IC50 value of 0.9 nM. It exhibits antimalarial activity in multidrug resistant strains in vitro with IC50 value of 227-734 nM. It has the potential for combination therapy with antivancer drugs in resistant leukemia. It is considerably less potent at muscarinic acetylcholine receptors with Ki value of 2.4 μM. It may be used as a potential antineoplastic agent for decreasing proliferation of various cancer cells. It may be used as a pharmacological chaperone to restore protein function for some mutated forms of hERG channels and correct folding defects. It was developed by Johnson & Johnson. Synonyms: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzim; Laridal; 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan; Hismanal; Histamen; Paralergin; R 42512; Retolen; Waruzol. Grade: ≥99% by HPLC. CAS No. 68844-77-9. Molecular formula: C28H31FN4O. Mole weight: 458.57.
Astemizole-d3
Labeled Astemizole. Nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic. Group: Biochemicals. Alternative Names: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxy-d3-phenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan-d3; Hismanal-d3; Histamen-d3; Paralergin-d3; R 42512-d3; R 43512-d3; Retolen-d3; Waruzol-d3. Grades: Highly Purified. CAS No. 1189961-39-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Astemizole-[d3]
Astemizole-[d3] is the labelled analogue of Astemizole, which is a nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with anticancer drugs such as doxorubicin in resistant leukemia. Antihistaminic. Synonyms: Astemizole D3; 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxy-d3-phenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan-d3; Hismanal-d3; Histamen-d3; Paralergin-d3; Retolen-d3; Waruzol-d3. Grade: ≥95%; ≥99% atom D. CAS No. 1189961-39-4. Molecular formula: C28H28D3FN4O. Mole weight: 461.59.
Astepyrone
Astepyrone is an antibiotic produced by Aspergillus terreus (IFO 4100). It has anti-ulcer effect. CAS No. 86925-92-0. Molecular formula: C9H12O5. Mole weight: 200.19.
Asterobactin
Asterobactin is a siderophore antibiotic produced by Nocardia asteroides IFM 0959. It has anti-tumor activity and inhibits HL-60 and HeLa cells at a concentration of 0.2-3.2 μg/mL, and Fe3+ can reduce its activity. Synonyms: Asterobactin A. CAS No. 482372-30-5. Molecular formula: C34H55N7O13. Mole weight: 769.84.
Asteroidenone
Asteroidenone. Group: Biochemicals. Alternative Names: (3'R)-3'-Hydroxy-b,b-caroten-4-one. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Asterric acid
Asterric acid is an Endothelin (ET) binding inhibitor produced by Aspergillus sp. Synonyms: Dimethylosoic acid,TAN 1415A, WF 12880A. Grade: >98%. CAS No. 577-64-0. Molecular formula: C17H16O8. Mole weight: 348.30.
Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells. Group: Biochemicals. Alternative Names: Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A. Grades: Highly Purified. CAS No. 577-64-0. Pack Sizes: 1mg. US Biological Life Sciences.
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Asterriquinol D dimethyl ether
Asterriquinol D dimethylether is a fungal metabolite first isolated from Aspergillus terreus as part of the asterriquinone complex. It is cytotoxic to NS-1 mouse myeloma cells with IC50 of 28 μg/ml. It has weak activity against tumor cells and the parasitic protozoan, Tritrichomonas foetus. Synonyms: 3,3'-(2,3,5,6-tetramethoxy-1,4-phenylene)bis-1H-indole. Grade: ≥95%. CAS No. 287117-66-2. Molecular formula: C26H24N2O4. Mole weight: 428.48.
Asterriquinone CT1
Asterriquinone CT1 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H26N2O4. Mole weight: 502.56.
Asterriquinone CT2
Asterriquinone CT2 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H28N2O4. Mole weight: 504.57.
Asterriquinone SU5228
Asterriquinone SU5228 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Molecular formula: C27H22N2O4. Mole weight: 438.47.
Asterriquinone SU5500
Asterriquinone SU5500 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Synonyms: 2,5-Bis[2-(3-methyl-2-butenyl)-1H-indole-3-yl]-3-acetoxy-6-hydroxy-1,4-benzoquinone. Molecular formula: C34H32N2O5. Mole weight: 548.64.
Astexin-1
Astexin-1 is an antimicrobial peptide produced by Asticcacaulis excentricus CB 48. It has antibacterial activity against gram-negative bacteria: Caulobacter crescentus CB15. Astexin-1 possesses a lasso structure, the isopeptide bond forming the macrolactam ring is between Gly1 and Asp9, an eight-residue loop above and a six-residue tail under the macrolactam ring are defined, with Glu17 above, Ser18 passing, and Arg19 under the ring. Grade: >98%.
Asticolorin A
Asticolorin A is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-70-6. Molecular formula: C33H30O7. Mole weight: 538.59.
Asticolorin B
Asticolorin B is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-71-7. Molecular formula: C33H28O7. Mole weight: 536.57.
Asticolorin C
Asticolorin C is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93395-44-9. Molecular formula: C33H28O9. Mole weight: 568.57.
Astilbin
Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 29838-67-3. Molecular formula: C21H22O11. Mole weight: 450.39. Purity: 0.98. Product ID: ACM29838673. Alfa Chemistry ISO 9001:2015 Certified.
Astilbin
Astilbin. Group: Biochemicals. Alternative Names: Taxifolin 3-rhamnoside. Grades: Plant Grade. CAS No. 29838-67-3. Pack Sizes: 20mg. Molecular Formula: C21H22O11, Molecular Weight: 450.392999999999. US Biological Life Sciences.
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Astilbin
Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation. Uses: Scientific research. Group: Natural products. CAS No. 29838-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0509.
ASTM Method D5501 Denatured Fuel Ethanol Calibration Set
ASTM Method D5501 Denatured Fuel Ethanol Calibration Set. Uses: For analytical and research use. Group: Hydrocarbons & petrochemicals; petroleum reference materials. Catalog: APS005857. Format: Mixture. Shipping: Room Temperature.
Astra Blue
Astra Blue is a stain for oligo- and polysaccharides such as cellulose in plant tissues. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25g, 50g. Molecular Formula: C47H52CuN14O6S3, Molecular Weight: 1068.75. US Biological Life Sciences.
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Astragalin
Astragalin. Group: Biochemicals. CAS No. 480-10-4. Pack Sizes: 5mg. US Biological Life Sciences.