A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Acid Yellow 99. Alternative Names: Acid complex yellow GR. CAS No. 10343-58-5. Purity: 40%. Product ID: ACM10343585. Molecular formula: C16H13CrN4NaO8S. Mole weight: 496.35. Alfa Chemistry - ISO 9001:32057 Certified.
Acid Yellow 9 monosodium salt
Acid Yellow 9 monosodium salt is an azo dye, degraded by Pseudomonas fluorescens as sole source of carbon, nitrogen and energy for the bacterium[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydrogen 4-aminoazobenzene-3,4'-disulphonate sodium salt. CAS No. 74543-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g. Product ID: HY-D0705.
Ac-IEPD-AFC
Ac-IEPD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 1135417-31-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-IEPD-AFC
Ac-IEPD-AFC is a substrate of Granzyme B[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135417-31-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1092.
Ac-IEPD-AFC
Ac-IEPD-AFC is a peptide whose sequence is preferred recognition motif for the serine protease granzyme B. It is a fluorogenic substrate. Alternative Names: IEPD; N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin); Ac-Ile-Glu-Pro-Asp-7-Amino-4-trifluoromethylcoumarin. Grades: ≥95%. CAS No. 1135417-31-0. Molecular formula: C32H38F3N5O11. Mole weight: 725.67.
Ac-IEPD-CHO
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM[1]. Ac-IEPD-CHO is also a caspase-8 inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352520-90-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10149.
Ac-IETD-AMC
Ac-IETD-AMC is a fluorogenic substrate for Procaspase-3 Cleaving Enzyme (Caspase-8 / Caspase-6 and Granzyme B). Alternative Names: Ac-Ile-Glu-Thr-Asp-AMC; Ac-Ile-Glu-Thr-Asp-MCA. CAS No. 348079-17-4. Molecular formula: C31H41N5O12. Mole weight: 675.68.
Ac-?IETD-?CHO
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191338-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113963.
Acifluorfen-methyl
Acifluorfen-methyl is an inhibitor of the heme and chlorophyll biosynthetic enzyme protoporphyrinogen oxidase (Protox). Acifluorfen-methyl is a photobleaching herbicide[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 50594-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147365.
Acifran
Acifran. Group: Biochemicals. Grades: Purified. CAS No. 72420-38-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Ac-Ile-Glu-Pro-Asp-AMC is a preferred substrate sequence of granzyme B, which is a mammalian serine protease involved in the induction of rapid target cell death by cytotoxic lymphocytes. Alternative Names: Ac-IEPD-AMC; L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin. Grades: 95%. CAS No. 216757-33-4. Molecular formula: C32H41N5O11. Mole weight: 671.69.
AC-ILE-TYR-GLY-GLU-PHE-NH2
AC-ILE-TYR-GLY-GLU-PHE-NH2. Alternative Names: N-Acetyl-L-isoleucyl-L-tyrosylglycyl-L-α-glutamyl-L-phenylalaninamide; P60c-src Substrate II. Grades: 95%. CAS No. 168781-78-0. Molecular formula: C33H44N6O9. Mole weight: 668.74.
Ac-ILVAGK-NH2
Ac-ILVAGK-NH2. CAS No. 1588764-53-7. Molecular formula: C30H56N8O7. Mole weight: 640.82.
Acimox impurity 1
Acimox impurity 1. Uses: For analytical and research use. Molecular formula: C6H16N2O. Mole weight: 132.21. Catalog: APB10975.
Acimox impurity 2
Acimox impurity 2. Uses: For analytical and research use. Molecular formula: C6H12N2. Mole weight: 112.18. Catalog: APB10976.
Acimox impurity 3
Acimox impurity 3. Uses: For analytical and research use. CAS No. 2101955-01-3. Molecular formula: C6H10N2. Mole weight: 110.16. Catalog: APB2101955013.
Acimox impurity 4
Acimox impurity 4. Uses: For analytical and research use. CAS No. 79068-45-4. Molecular formula: C6H8N2O2. Mole weight: 140.14. Catalog: APB79068454.
Acimox impurity 5
Acimox impurity 5. Uses: For analytical and research use. CAS No. 1378839-68-9. Molecular formula: C6H6N2O3. Mole weight: 154.13. Catalog: APB1378839689.
Acimox impurity 6
Acimox impurity 6. Uses: For analytical and research use. CAS No. 77666-94-5. Molecular formula: C6H4N2O2. Mole weight: 136.11. Catalog: APB77666945.
Acimox impurity 7
Acimox impurity 7. Uses: For analytical and research use. CAS No. 1368358-42-2. Molecular formula: C6H4N2O3. Mole weight: 152.11. Catalog: APB1368358422.
Acimox impurity 8
Acimox impurity 8. Uses: For analytical and research use. CAS No. 2734844-49-4. Molecular formula: C6H6N2O4. Mole weight: 170.12. Catalog: APB2734844494.
Acipimox
Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: K-9321. CAS No. 51037-30-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0283.
Acipimox
Antilipemic. Group: Biochemicals. Alternative Names: 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide; 5- methyl pyrazinecarboxylic Acid 4-Oxide; K 9321; Olbemox; Olbetam. Grades: Highly Purified. CAS No. 51037-30-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Acipimox Impurity 1
Acipimox Impurity 1. Uses: For analytical and research use. Alternative Names: 2-carboxy-5-methylpyrazine 1,4-dioxide. Molecular formula: C6H6N2O4. Mole weight: 170.12. Catalog: APB03244.
Acipimox Impurity 2
Acipimox Impurity 2. Uses: For analytical and research use. Alternative Names: 2-methylpyrazine 1,4-dioxide. CAS No. 32046-26-7. Molecular formula: C5H6N2O2. Mole weight: 126.11. Catalog: APB32046267.
Acipimox Impurity 3
Acipimox Impurity 3. Uses: For analytical and research use. Alternative Names: 3-carboxy-5-methylpyrazine 1-oxide. CAS No. 51037-31-1. Molecular formula: C6H6N2O3. Mole weight: 154.12. Catalog: APB51037311.
acireductone dioxygenase [iron(II)-requiring]
Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Enzyme Commission Number: EC 1.13.11.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0573; acireductone dioxygenase [iron(II)-requiring]; EC 1.13.11.54; ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Cat No: EXWM-0573.
acireductone dioxygenase (Ni2+-requiring)
Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Enzyme Commission Number: EC 1.13.11.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0572; acireductone dioxygenase (Ni2+-requiring); EC 1.13.11.53; ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Cat No: EXWM-0572.
acireductone synthase
This bifunctional enzyme first enolizes the substrate to form the intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one. The acireductone represents a branch point in the methione-salvage pathway as it is used in the formation of formate, CO and 3-(methylthio)propanoate by EC 1.13.11.53 [acireductone dioxygenase (Ni2+-requiring)] and of formate and 4-methylthio-2-oxobutanoate either by a spontaneous reaction under aerobic conditions or by EC 1.13.11.54 {acireductone dioxygenase [iron(II)-requiring]}. Group: Enzymes. Synonyms: E1; E-1 enolase-phosphatase. Enzyme Commission Number: EC 3.1.3.77. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3682; acireductone synthase; EC 3.1.3.77; E1; E-1 enolase-phosphatase. Cat No: EXWM-3682.
Acitretin
Acitretin. Group: Biochemicals. Alternative Names: 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Grades: Highly Purified. CAS No. 55079-83-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C21H26O3. US Biological Life Sciences.
Worldwide
Acitretin
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimers disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 10-1670. CAS No. 55079-83-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0107.
Acitretin
Acitretin is a second-generation oral retinoid derived from etretinate, used for severe psoriasis and other disorders of keratinization. It is a carboxylic acid metabolite of etretinate with a shorter half-life and no detectable accumulation of etretinate in adipose tissue. Applications: Acitretin is indicated for the treatment of severe, recalcitrant plaque psoriasis, particularly the pustular and erythrodermic variants. it is also used for disorders of cornification such as ichthyosis and darier's disease. Category: Active pharmaceutical ingredients. Synonyms: Etretin; Soriatane; Neotigason; Acitretine; Acitretina. CAS No. 55079-83-9. Product ID: API0231583. Molecular formula: C21H26O3. Mole weight: 326.4. EINECS: 259-474-4. InChIKey: IHUNBGSDBOWDMA-AQFIFDHZSA-N. Appearance: Yellow or greenish-yellow crystalline powder.
Acitretin EP Impurity A (Acitretin USP Related Compound A, 13-cis-Acitretin)
Acitretin EP Impurity A (Acitretin USP Related Compound A, 13-cis-Acitretin). Uses: For analytical and research use. Alternative Names: (2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. CAS No. 69427-46-9. Molecular formula: C21H26O3. Mole weight: 326.44. Catalog: APB69427469.
Acitretin impurity 1
Acitretin impurity 1. Uses: For analytical and research use. Molecular formula: C27H34O9. Mole weight: 502.56. Catalog: APB10174.
Acitretin Impurity 1
Acitretin Impurity 1. Uses: For analytical and research use. Alternative Names: (2E,4E,6E,8E)-isopropyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate. CAS No. 74479-46-2. Molecular formula: C24H32O3. Mole weight: 368.52. Catalog: APB74479462.
Acitretin Impurity 10
Acitretin Impurity 10. Uses: For analytical and research use. Alternative Names: (2E,4E,6E,8E)-3-ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-7-methylnona-2,4,6,8-tetraenoic acid. Molecular formula: C22H28O3. Mole weight: 340.46. Catalog: APB03236.
Acitretin Impurity 11
Acitretin Impurity 11. Uses: For analytical and research use. Alternative Names: (2E,4E,6E,8E)-butyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate. CAS No. 74479-40-6. Molecular formula: C25H34O3. Mole weight: 382.54. Catalog: APB74479406.
Acitretin Impurity 2
Acitretin Impurity 2. Uses: For analytical and research use. Alternative Names: 4,4'-((1E,3E,5E,7E,9E)-3,8-dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene). CAS No. 1621284-00-1. Molecular formula: C32H40O2. Mole weight: 456.67. Catalog: APB1621284001.
Acitretin Impurity 3
Acitretin Impurity 3. Uses: For analytical and research use. Alternative Names: 4,4'-((1E,3E,5Z,7E,9E)-3,8-dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene). Molecular formula: C32H40O2. Mole weight: 456.67. Catalog: APB03128.
Acitretin Impurity 4
Acitretin Impurity 4. Uses: For analytical and research use. Alternative Names: (2Z,4E,6E,8E)-9-(3-(hydroxymethyl)-4-methoxy-2,6-dimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Molecular formula: C21H26O4. Mole weight: 342.44. Catalog: APB03238.
Acitretin Related Compound A
Acitretin Related Compound A. Uses: For analytical and research use. CAS No. 69427-46-9. Mole weight: 326.43. Catalog: AP69427469.
Acivicin
Azaserine and Acivicin are classical and irreversible inhibitors of γ -Glutamyl transpeptidase. Group: Biochemicals. Alternative Names: (αS,5S)-. Grades: Highly Purified. CAS No. 42228-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-125; U-42126. CAS No. 42228-92-2. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-W016586.
Acivicin
Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Alternative Names: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grades: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57.
Acivicin hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A.
Ac-KQKLR-AMC TFA
Ac-KQKLR-AMC TFA is a substrate peptide of Cathepsin S fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). Ac-KQKLR-AMC TFA can be used to measure Cathepsin S activity)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cathepsin S substrate TFA. CAS No. 2237216-84-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P5378A.
Aclacinomycin
Aclacinomycin is an anthracycline drug that is used in the treatment of cancer. Grades: ≥95%. CAS No. 66676-88-8.
Aclacinomycin A
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aclarubicin. CAS No. 57576-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N2306.
aclacinomycin-A oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A (cf. EC 1.1.3.45) and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y. Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.3.3.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1375; aclacinomycin-A oxidase; EC 1.3.3.14; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-1375.
Aclacinomycin B
Aclacinomycin B is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. Alternative Names: Antibiotic MA 144B1; Aclarubicin B. CAS No. 57596-79-9. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclacinomycin HCl
Aclacinomycin HCl. Group: Biochemicals. Alternative Names: Aclarubicin HCl. Grades: Highly Purified. CAS No. 75443-99-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C42H53NO15·HCl. US Biological Life Sciences.
Worldwide
aclacinomycin methylesterase
The enzyme is involved in the modification of the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species. Group: Enzymes. Synonyms: RdmC; aclacinomycin methyl esterase. Enzyme Commission Number: EC 3.1.1.95. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3524; aclacinomycin methylesterase; EC 3.1.1.95; RdmC; aclacinomycin methyl esterase. Cat No: EXWM-3524.
aclacinomycin-N oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y (cf. EC 1.3.3.14, aclacinomycin A oxidase). Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.1.3.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0418; aclacinomycin-N oxidase; EC 1.1.3.45; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-0418.
aclacinomycin-T 2-deoxy-L-fucose transferase
The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564.
Aclacinomycin Y
Aclacinomycin Y is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. CAS No. 66789-14-8. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclarubicin A
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Alternative Names: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88.
Aclarubicin hydrochloride
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Alternative Names: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33.
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210345-03-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1093.
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, 5 and 9. Alternative Names: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine; N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-9 substrate; L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; (4S,7S,10S,13S)-10-((1H-imidazol-5-yl)methyl)-7-(2-carboxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid. Grades: ≥95%. CAS No. 210345-03-2. Molecular formula: C33H38F3N7O11. Mole weight: 765.69.
Ac-LEHD-AFC
Ac-LEHD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 210345-03-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-LEHD-AMC
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292633-16-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1652.
Ac-LEHD-CHO
Ac-LEHD-CHO is a Caspase-9 inhibitor. Caspase 9 is a cysteine protease acting as an initiating enzyme in apoptosis pathways. Alternative Names: Ac-DL-Leu-DL-Glu-DL-His-DL-Asp-al; Ac-Leu-Glu-His-Asp-CHO; 4-({1-[(1-carboxy-3-oxopropan-2-yl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl}carbamoyl)-4-(2-acetamido-4-methylpentanamido)butanoic acid. CAS No. 319494-38-7. Molecular formula: C23H34N6O9. Mole weight: 538.55.
Ac-LEHD-pNA
Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.). Uses: Scientific research. Category: Peptides. CAS No. 921771-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5348.
Aclerastide
Aclerastide is an angiotensin receptor agonist, potentially used to treat tissue regeneration in diabetic ulcers and scars. Alternative Names: Norleu3-a(1-7); UNII-YYD6UT8T47; Asp-arg-nle-tyr-ile-his-pro; DSC127; DSC-127; USB-001. Grades: ≥98% by HPLC. CAS No. 227803-63-6. Molecular formula: C42H64N12O11. Mole weight: 913.0406.