A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, 5 and 9. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine; N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-9 substrate; L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; (4S,7S,10S,13S)-10-((1H-imidazol-5-yl)methyl)-7-(2-carboxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid. Grade: ≥95%. CAS No. 210345-03-2. Molecular formula: C33H38F3N7O11. Mole weight: 765.69.
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210345-03-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1093.
Ac-LEHD-AMC
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 292633-16-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1652.
Ac-LEHD-CHO
Ac-LEHD-CHO is a Caspase-9 inhibitor. Caspase 9 is a cysteine protease acting as an initiating enzyme in apoptosis pathways. Synonyms: Ac-DL-Leu-DL-Glu-DL-His-DL-Asp-al; Ac-Leu-Glu-His-Asp-CHO; 4-({1-[(1-carboxy-3-oxopropan-2-yl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl}carbamoyl)-4-(2-acetamido-4-methylpentanamido)butanoic acid. CAS No. 319494-38-7. Molecular formula: C23H34N6O9. Mole weight: 538.55.
Ac-LEHD-pNA
Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.). Uses: Scientific research. Category: Peptides. CAS No. 921771-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5348.
Aclerastide
Aclerastide is an angiotensin receptor agonist, potentially used to treat tissue regeneration in diabetic ulcers and scars. Synonyms: Norleu3-a(1-7); UNII-YYD6UT8T47; Asp-arg-nle-tyr-ile-his-pro; DSC127; DSC-127; USB-001. Grade: ≥98% by HPLC. CAS No. 227803-63-6. Molecular formula: C42H64N12O11. Mole weight: 913.0406.
Ac-Leu-Arg-AMC
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate. Synonyms: L-Argininamide, N-acetyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grade: ≥95%. CAS No. 929621-79-4. Molecular formula: C24H34N6O5. Mole weight: 486.56.
Ac-leu-val-lys-aldehyde
Ac-leu-val-lys-aldehyde. Alternative Names: CATHEPSIN B INHIBITOR II;AC-LEU-VAL-L-LYSINAL;AC-LEU-VAL-LYS-ALDEHYDE;AC-LVK-CHO. CAS No. 147600-40-6. Product ID: ACM147600406. Molecular formula: C19H36N4O4. Mole weight: 384.51. Alfa Chemistry - ISO 9001:32057 Certified.
AC-Leu-val-lys-aldehyde
AC-Leu-val-lys-aldehyde showed a stronger inhibition of cathepsin B (IC50 = 4 nM) than leupeptin (IC50 = 0.31 μM). Synonyms: Ac-LVK-aldehyde; (S)-6-Amino-2-[[N-(N-acetyl-L-leucyl)-L-valyl]amino]hexanal. CAS No. 147600-40-6. Molecular formula: C19H36N4O4. Mole weight: 384.51.
Ac-LEVD-CHO
Ac-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 402832-01-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136727.
Ac-LEVD-CHO trifluoroacetate salt
Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grade: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5.
Acl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U. AA↑CGTT TTGC↓AA. Activity: 3000-5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 0.05% Triton X-100; 50% glycerol. Cat No: RE-1009EN.
Aclidinium Bromide
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Synonyms: trade name: Eklira Genuair; Tudorza Genuair; Bretaris Genuair. Grade: 0.98. CAS No. 320345-99-1. Molecular formula: C26H30BrNO4S2. Mole weight: 564.553.
Aclidinium Bromide
Aclidinium Bromide is a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: (3R)-3-[(2-Hydroxy-2, 2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; (3R)-(2-Hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; Aclidinium Bromide; Genuair; LAS 34273; LAS-W 330. Grades: Highly Purified. CAS No. 320345-99-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Aclidinium Bromide
Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LAS 34273; LAS-W 330. CAS No. 320345-99-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14144.
Aclidinium Bromide-[d5]
Aclidinium Bromide-[d5] is a labelled analogue of Aclidinium Bromide. Aclidinium Bromide is a long-acting muscarinic antagonist (LAMA) used for the treatment of chronic obstructive pulmonary disease (COPD). Synonyms: (1s,4s)-3-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-1-[3-(2H5)phenoxypropyl]-1-azabicyclo[2.2.2]octan-1-ium bromide; (3R)-3-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane-d5 Bromide; (3R)-(2-Hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane-d5 Bromide; Aclidinium-d5 Bromide; Genuair-d5; LAS 34273-d5; LAS-W 330-d5. Grade: 95% by HPLC; 98% atom D. Molecular formula: C22H21D5BrNO3. Mole weight: 437.38.
Aclidinium Bromide Dimer Impurity
Aclidinium Bromide Dimer Impurity. Uses: For analytical and research use. Molecular formula: C37H44Br2N2O6S4. Mole weight: 900.81. Catalog: APB06492.
Aclidinium bromide Impurity 1
Aclidinium bromide Impurity 1. Uses: For analytical and research use. Molecular formula: C20H25Br2NO3S2. Mole weight: 551.35. Catalog: APB06491.
Aclidinium bromide Impurity 11
Aclidinium bromide Impurity 11. Uses: For analytical and research use. Molecular formula: C38H44BrNO3. Mole weight: 642.68. Catalog: APB06495.
Aclidinium bromide Impurity 12
Aclidinium bromide Impurity 12. Uses: For analytical and research use. CAS No. 320347-97-5. Molecular formula: C17H19NO3S2. Mole weight: 349.46. Catalog: APB320347975.
Aclidinium bromide Impurity 2
Aclidinium bromide Impurity 2. Uses: For analytical and research use. CAS No. 1708930-15-7. Molecular formula: C16H24BrNO2. Mole weight: 342.28. Catalog: APB1708930157.
Aclidinium bromide Impurity 3
Aclidinium bromide Impurity 3. Uses: For analytical and research use. CAS No. 320346-75-6. Molecular formula: C25H28BrNO4S2. Mole weight: 550.53. Catalog: APB320346756.
Aclidinium bromide Impurity 4
Aclidinium bromide Impurity 4. Uses: For analytical and research use. CAS No. 28569-88-2. Molecular formula: C12H12O3S2. Mole weight: 268.35. Catalog: APB28569882.
Aclidinium bromide Impurity 5/Titropium bromide EP impurity E
Aclidinium bromide Impurity 5/Titropium bromide EP impurity E. Uses: For analytical and research use. CAS No. 26447-85-8. Molecular formula: C11H10O3S2. Mole weight: 254.32. Catalog: APB26447858.
Aclidinium bromide Impurity 6
Aclidinium bromide Impurity 6. Uses: For analytical and research use. Molecular formula: C16H24BrNO2. Mole weight: 342.28. Catalog: APB06493.
Aclidinium bromide Impurity 8
Aclidinium bromide Impurity 8. Uses: For analytical and research use. CAS No. 4075-58-5. Molecular formula: C8H8O3S. Mole weight: 184.21. Catalog: APB4075585.
Aclidinomycin A
Aclidinomycin A is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O6. Mole weight: 415.44.
Aclidinomycin B
Aclidinomycin B is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O7. Mole weight: 431.44.
Aclimostat
Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZGN-1061. CAS No. 2082752-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114196.
Ac-Linaclotide
Ac-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: Ac-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-aspargenyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1-6),(2-10),(5-13)-tris(disulfide); Ac-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (disulfide bridges between 1-6, 2-10 and 5-13 Cysteines); N-Acetyl-linaclotide; L-Tyrosine, N-acetyl-L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide). CAS No. 1422389-17-0. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76.
Aclonifen
Aclonifen. Group: Biochemicals. Alternative Names: 2-Chloro-6-nitro-3-phenoxyaniline; 2-Chloro-6-nitro-3-phenoxybenzenamine; Bandren; Bandur; CME 127; KUB 3359. Grades: Highly Purified. CAS No. 74070-46-5. Pack Sizes: 1g. Molecular Formula: C12H9ClN2O3, Molecular Weight: 264.66. US Biological Life Sciences.
Worldwide
Aclonifen-[d5]
A labelled analogue of Aclonifen, which is used as a pesticide and herbicide. Synonyms: 2-Chloro-6-nitro-3-phenoxybenzenamine-d5; 2-Chloro-6-nitro-3-phenoxyaniline-d5; Bandren-d5. Grade: >95%. Molecular formula: C12H4D5ClN2O3. Mole weight: 269.70.
Acloproxalap
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADX-629. CAS No. 1824609-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147240.
AclW I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme about 50% of the dna fragments can be ligated with t4 dna ligase and recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 100U; 500U. GGATC(N)4↑ CCTAG(N)5&darr. Activity: 1000-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus W2131. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1010EN.
Ac-Lys-AMC
Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 156661-42-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128919.
Ac-Lys-AMC
Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Synonyms: (S)-2-Acetamido-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide; N2-Acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; Hexanamide, 2-(acetylamino)-6-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-. Grade: ≥98%. CAS No. 156661-42-6. Molecular formula: C18H23N3O4. Mole weight: 345.40.
Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Synonyms: Ac-KQLR-AFC; L-Argininamide, N2-acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N2-Acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-argininamide. Grade: ≥95%. CAS No. 1802078-38-1. Molecular formula: C35H51F3N10O8. Mole weight: 796.84.
The major encephalitogenic epitope in myelin basic protein (MBP). Synonyms: Ac-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys; MBP (1-11), mouse; AC-ASQKRPSQRSK-OH; Acetyl-myelin Basic Protein (Mouse,1-11); Myelin Basic Protein (2-12) Acetyl; N-acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysine. Grade: ≥95%. CAS No. 125366-42-9. Molecular formula: C53H95N21O18. Mole weight: 1314.45.
ACMO
ACMO. Mole weight: 141.
Ac-Nle-Pro-Nle-Asp-AMC
Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Synonyms: Ac-Nle-Pro-Nle-Asp-7-amido-4-Methylcoumarin; Ac-nLPnLD-AMC; N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; (3S)-4-Hydroxy-3-({(2S)-1-hydroxy-2-[(hydroxy{(2S)-1-[N-(1-hydroxyethylidene)-L-norleucyl]-2-pyrrolidinyl}methylene)amino]hexylidene}amino)-4-[(4-methyl-2-oxo-2H-chromen-7-yl)imino]butanoic acid. Grade: ≥98%. CAS No. 355140-49-7. Molecular formula: C33H45N5O9. Mole weight: 655.74.
Ac-Nle-Pro-Nle-Asp-AMC
Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 355140-49-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P2016.
Ac-Octreotide
Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N2.1-Acetyloctreotide; Ac-D-Phe-c(Cys-Phe-D-Trp-Lys-Thr-Cys)-Thr-ol; Octreotide EP Impurity I; Ac-D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); Acetyl-Octreotide; Acetyl-Phe1-octreotide; N-Acetyl-D-phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Aco I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA(dam-, dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with acoi more than 90% of lambda dna fragments can be ligated with t4 dna ligase at 16°c and recut. Group: Restriction Enzymes. Y↑GGCCR RCCGG↓Y. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1011EN.
Acolbifene
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 is the compound having the highest affinity for the estrogen receptor, including estradiol. It has higher affinity for the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells. Synonyms: EM-652; SCH 57068; (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol. Grade: ≥98%. CAS No. 182167-02-8. Molecular formula: C29H31NO4. Mole weight: 457.57.
Acolbifene hydrochloride
Acolbifene hydrochloride, an active metabolite of EM800, is an orally active selective estrogen receptor modulator (SERM) with anticarcinogenic properties. It has a potent and pure antiestrogenic effect on mammary gland and uterus, and inhibits estradiol (E2)-induced transcriptional activity of ERα and ERβ with IC50s of 2 and 0.4 nM, respectively. Synonyms: EM-652 hydrochloride; SCH 57068 hydrochloride; 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride, (2S)-; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol hydrochloride. Grade: ≥98%. CAS No. 252555-01-4. Molecular formula: C29H32ClNO4. Mole weight: 494.02.
Acoltremon
Acoltremon (WS-12; AR-15512) is a potent and selective TRPM8 agonist, the menthol derivative, as a cooling agent. Acoltremon shows analgesic effect, and can be used in chronic neuropathic pain research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WS-12; AR-15512; AVX-012. CAS No. 68489-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-108449.
Aconine
Aconine. Group: Biochemicals. Alternative Names: Jesaconine. Grades: Plant Grade. CAS No. 509-20-6. Pack Sizes: 10mg. Molecular Formula: C25H41NO9, Molecular Weight: 499.594. US Biological Life Sciences.
Worldwide
aconitate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.6. CAS No. 9025-1-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4806; aconitate decarboxylase; EC 4.1.1.6; 9025-01-8; cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Cat No: EXWM-4806.
aconitate Δ-isomerase
cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. This isomerization could take place either in a direct cis-trans interconversion or by an allylic rearrangement; the enzyme has been shown to catalyse the latter change. Group: Enzymes. Synonyms: aconitate isomerase. Enzyme Commission Number: EC 5.3.3.7. CAS No. 37318-48-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5504; aconitate Δ-isomerase; EC 5.3.3.7; 37318-48-2; aconitate isomerase. Cat No: EXWM-5504.
aconitate hydratase
Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. An iron-sulfur protein, containing a [4Fe-4S] cluster to which the substrate binds. Group: Enzymes. Synonyms: cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Enzyme Commission Number: EC 4.2.1.3. CAS No. 9024-25-3. Aconitase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5020; aconitate hydratase; EC 4.2.1.3; 9024-25-3; cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Cat No: EXWM-5020.
Aconitic acid
Aconitic acid (NSC 7616) is an organic acid, and can be isolated from seeds of Brassica oleracea var. acephala (kale). Aconitic acid has antifungal activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 7616. CAS No. 499-12-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-W016814A.
Aconitic acid
Aconitic acid. Alternative Names: (1Z)-1-propene-1,2,3-tricarboxylic acid. CAS No. 499-12-7. Purity: >98.0%. Product ID: FFC-AR-499127. Molecular formula: C6H6O6. Mole weight: 174.11. IUPAC Name: prop-1-ene-1,2,3-tricarboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Aconitic Acid
Solid;Solid;colourless or yellow crystals, leaves, or plates; pleasant winey acid taste; almost odourless. Molecular formula: C6H6O6. Mole weight: 174.11g/mol. IUPAC Name: (Z)-prop-1-ene-1,2,3-tricarboxylic acid. SMILES: C(C(=CC(=O)O)C(=O)O)C(=O)O. InChI: InChI=1S/C6H6O6/c7-4(8)1-3(6(11)12)2-5(9)10/h1H,2H2,(H,7,8)(H,9,10)(H,11,12)/b3-1-.
Aconitine
Neurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In cultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization. Group: Biochemicals. Alternative Names: (1α, 3α, 6α, 14α, 15α, 16 β ) -20-Ethyl-1, 6, 16-trimethoxy-4- (methoxymethyl) aconitane-3, 8, 13, 14, 15-pentol 8-Acetate 14-Benzoate. Grades: Highly Purified. CAS No. 302-27-2. Pack Sizes: 10mg. US Biological Life Sciences.
Acoramidis (AG10) is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) is used in the study for transthyretin amyloidosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG10. CAS No. 1446711-81-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109165.
Acoramidis
Acoramidis. Category: Active pharmaceutical ingredients. CAS No. 1446711-81-4. Product ID: API1446711814. Molecular formula: C15H17FN2O3. Mole weight: 292.31.
Acoramidis hydrochloride
Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG10 hydrochloride. CAS No. 2242751-53-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109165A.
Acorus calamus root oil
Acorus calamus root oil. Alternative Names: Calamus root oil. CAS No. 84775-39-3. Product ID: FFC-AR-84775393. Alfa Chemistry - ISO 9001:32057 Certified.
Acorus Calamus (Sweet Flag)
Acorus Calamus (Sweet Flag).
CA, FL & NJ
Acotiamide
Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide; MZ-338; UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554.
Acotiamide
Acotiamide. Uses: For analytical and research use. Alternative Names: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.55. Catalog: APB185106165.
Acotiamide HCl
Acotiamide HCl. Uses: For analytical and research use. Alternative Names: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride. CAS No. 185104-11-4. Molecular formula: C21H31ClN4O5S. Mole weight: 487.01. Catalog: APB185104114.