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Aclacinomycin B is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. Synonyms: Antibiotic MA 144B1; Aclarubicin B. CAS No. 57596-79-9. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclacinomycin HCl
Aclacinomycin HCl. Group: Biochemicals. Alternative Names: Aclarubicin HCl. Grades: Highly Purified. CAS No. 75443-99-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C42H53NO15·HCl. US Biological Life Sciences.
Worldwide
aclacinomycin methylesterase
The enzyme is involved in the modification of the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species. Group: Enzymes. Synonyms: RdmC; aclacinomycin methyl esterase. Enzyme Commission Number: EC 3.1.1.95. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3524; aclacinomycin methylesterase; EC 3.1.1.95; RdmC; aclacinomycin methyl esterase. Cat No: EXWM-3524.
aclacinomycin-N oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y (cf. EC 1.3.3.14, aclacinomycin A oxidase). Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.1.3.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0418; aclacinomycin-N oxidase; EC 1.1.3.45; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-0418.
aclacinomycin-T 2-deoxy-L-fucose transferase
The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564.
Aclacinomycin Y
Aclacinomycin Y is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. CAS No. 66789-14-8. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclame
Aclame is an intense sweetener that is about 2000 times sweeter than sucrose. Synonyms: L-α-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide; Alitame; L-aspartyl-D-alanine-N-(2,2,4,4-tetramethylthietan-3-yl)amide; 3-(L-aspartyl-D-alaninamido)-2,2,4,4-tetramethylthietane; (S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)butanoic acid; (S)-3-((R)-1-(2,2,4,4-Tetramethylthietan-3-ylcarbamoyl)ethylcarbamoyl)-3-aminopropanoic acid. Grades: 95%. CAS No. 80863-62-3. Molecular formula: C14H25N3O4S. Mole weight: 331.43.
Aclarubicin
Aclarubicin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 57576-44-0. Molecular Formula: C42H53NO15. Mole Weight: 811.88. Catalog: APB57576440.
Aclarubicin A
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88.
Aclarubicin hydrochloride
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33.
Ac-LEHD-AFC
Ac-LEHD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 210345-03-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, 5 and 9. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine; N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-9 substrate; L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; (4S,7S,10S,13S)-10-((1H-imidazol-5-yl)methyl)-7-(2-carboxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid. Grades: ≥95%. CAS No. 210345-03-2. Molecular formula: C33H38F3N7O11. Mole weight: 765.69.
Ac-LEHD-AMC
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9. Ac-LEHD-AMC is cleaved by caspase-9 to release the fluorescent moiety AMC, which can be used to quantify caspase-9 activity. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 292633-16-0. Molecular formula: C33H41N7O11. Mole weight: 711.7.
Aclerastide
Aclerastide is an angiotensin receptor agonist, potentially used to treat tissue regeneration in diabetic ulcers and scars. Synonyms: Norleu3-a(1-7); UNII-YYD6UT8T47; Asp-arg-nle-tyr-ile-his-pro; DSC127; DSC-127; USB-001. Grades: ≥98% by HPLC. CAS No. 227803-63-6. Molecular formula: C42H64N12O11. Mole weight: 913.0406.
Ac-LETD-AFC
Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 210345-02-1. Molecular formula: C31H38F3N5O12. Mole weight: 729.7.
Ac-Leu-Arg-AMC
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate. Synonyms: L-Argininamide, N-acetyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929621-79-4. Molecular formula: C24H34N6O5. Mole weight: 486.56.
Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grades: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5.
Acl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U. AA↑CGTT TTGC↓AA. Activity: 3000-5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 0.05% Triton X-100; 50% glycerol. Cat No: RE-1009EN.
Aclidinium Bromide
Aclidinium Bromide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 320345-99-1. Molecular Formula: C26H30BrNO4S2. Mole Weight: 564.55. Catalog: APB320345991.
Aclidinium Bromide
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Synonyms: trade name: Eklira Genuair; Tudorza Genuair; Bretaris Genuair. Grades: 0.98. CAS No. 320345-99-1. Molecular formula: C26H30BrNO4S2. Mole weight: 564.553.
Aclidinium Bromide
Aclidinium Bromide is a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: (3R)-3-[(2-Hydroxy-2, 2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; (3R)-(2-Hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; Aclidinium Bromide; Genuair; LAS 34273; LAS-W 330. Grades: Highly Purified. CAS No. 320345-99-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Aclidinium Bromide
Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAS 34273; LAS-W 330. CAS No. 320345-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14144.
Aclidinium Bromide 3S-Isomer
Aclidinium Bromide 3S-Isomer. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H30BrNO4S2. Mole Weight: 564.55. Catalog: APB06494.
Aclidinium Bromide Dimer Impurity
Aclidinium Bromide Dimer Impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C37H44Br2N2O6S4. Mole Weight: 900.81. Catalog: APB06492.
Aclidinium bromide Impurity 1
Aclidinium bromide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H25Br2NO3S2. Mole Weight: 551.35. Catalog: APB06491.
Aclidinium bromide Impurity 11
Aclidinium bromide Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C38H44BrNO3. Mole Weight: 642.68. Catalog: APB06495.
Aclidinium bromide Impurity 12
Aclidinium bromide Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 320347-97-5. Molecular Formula: C17H19NO3S2. Mole Weight: 349.46. Catalog: APB320347975.
Aclidinium bromide Impurity 2
Aclidinium bromide Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1708930-15-7. Molecular Formula: C16H24BrNO2. Mole Weight: 342.28. Catalog: APB1708930157.
Aclidinium bromide Impurity 3
Aclidinium bromide Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 320346-75-6. Molecular Formula: C25H28BrNO4S2. Mole Weight: 550.53. Catalog: APB320346756.
Aclidinium bromide Impurity 4
Aclidinium bromide Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 28569-88-2. Molecular Formula: C12H12O3S2. Mole Weight: 268.35. Catalog: APB28569882.
Aclidinium bromide Impurity 5/Titropium bromide EP impurity E
Aclidinium bromide Impurity 5/Titropium bromide EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 26447-85-8. Molecular Formula: C11H10O3S2. Mole Weight: 254.32. Catalog: APB26447858.
Aclidinium bromide Impurity 6
Aclidinium bromide Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H24BrNO2. Mole Weight: 342.28. Catalog: APB06493.
Aclidinium bromide Impurity 8
Aclidinium bromide Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4075-58-5. Molecular Formula: C8H8O3S. Mole Weight: 184.21. Catalog: APB4075585.
Aclidinium-d5 Bromide
Aclidinium-d5 Bromide. Group: Biochemicals. Alternative Names: (3R)-3-[(2-Hydroxy-2, 2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane-d5 Bromide; (3R)-(2-Hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane-d5 Bromide; Aclidinium-d5 Bromide; Genuair-d5; LAS 34273-d5; LAS-W 330-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H25D5BrNO4S2, Molecular Weight: 569.59. US Biological Life Sciences.
Worldwide
Aclidinomycin A
Aclidinomycin A is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O6. Mole weight: 415.44.
Aclidinomycin B
Aclidinomycin B is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O7. Mole weight: 431.44.
Ac-Linaclotide
Ac-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: Ac-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-aspargenyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1-6),(2-10),(5-13)-tris(disulfide); Ac-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (disulfide bridges between 1-6, 2-10 and 5-13 Cysteines); N-Acetyl-linaclotide; L-Tyrosine, N-acetyl-L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide). CAS No. 1422389-17-0. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76.
Aclonifen
Aclonifen. Group: Biochemicals. Alternative Names: 2-Chloro-6-nitro-3-phenoxyaniline; 2-Chloro-6-nitro-3-phenoxybenzenamine; Bandren; Bandur; CME 127; KUB 3359. Grades: Highly Purified. CAS No. 74070-46-5. Pack Sizes: 1g. Molecular Formula: C12H9ClN2O3, Molecular Weight: 264.66. US Biological Life Sciences.
Worldwide
Aclonifen-d5
Aclonifen-d5. Group: Biochemicals. Alternative Names: 2-Chloro-6-nitro-3-phenoxybenzenamine; 2-Chloro-6-nitro-3-phenoxyaniline; Bandren; Bandur; CME 127; KUB 3359. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C12H4D5ClN2O3, Molecular Weight: 269.7. US Biological Life Sciences.
Worldwide
AclW I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme about 50% of the dna fragments can be ligated with t4 dna ligase and recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 100U; 500U. GGATC(N)4↑ CCTAG(N)5&darr. Activity: 1000-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus W2131. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1010EN.
Ac-Lys-AMC
Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Synonyms: (S)-2-Acetamido-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide; N2-Acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; Hexanamide, 2-(acetylamino)-6-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-. Grades: ≥98%. CAS No. 156661-42-6. Molecular formula: C18H23N3O4. Mole weight: 345.40.
Ac-Lys-AMC
Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156661-42-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-128919.
Ac-Lys-D-Ala-D-Ala-OH
Ac-Lys-D-Ala-D-Ala-OH. Group: Biochemicals. Alternative Names: Na-Acetyl-Lys-D-Ala-D-Ala-OH. Grades: Highly Purified. CAS No. 28845-97-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences.
Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Synonyms: Ac-KQLR-AFC; L-Argininamide, N2-acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N2-Acetyl-L-lysyl-L-glutaminyl-L-leucyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-argininamide. Grades: ≥95%. CAS No. 1802078-38-1. Molecular formula: C35H51F3N10O8. Mole weight: 796.84.
Ac-MBP 1-11
The major encephalitogenic epitope in myelin basic protein (MBP). Synonyms: Ac-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys; MBP (1-11), mouse; AC-ASQKRPSQRSK-OH; Acetyl-myelin Basic Protein (Mouse,1-11); Myelin Basic Protein (2-12) Acetyl; N-acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysine. Grades: ≥95%. CAS No. 125366-42-9. Molecular formula: C53H95N21O18. Mole weight: 1314.45.
Acmella Oleracea Extract
Acmella Oleracea extract, a potent natural alternative to Botox, can be used in medical treatments and has anti-aging effects. The extract features analgesic alkylamides called Spilanthol. It has been used to treat skin diseases such as ringworm, athletes' foot, and nail infections.
Ac-met-glu-oh
Heterocyclic Organic Compound. Alternative Names: AC-MET-GLU-OH. CAS No. 105777-14-8. Molecular formula: C12H20N2O6S. Mole weight: 320.36. Catalog: ACM105777148.
Ac-Nle-Pro-Nle-Asp-AMC
Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Synonyms: Ac-Nle-Pro-Nle-Asp-7-amido-4-Methylcoumarin; Ac-nLPnLD-AMC; N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine; L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; (3S) -4-Hydroxy-3- ({ (2S) -1-hydroxy-2-[ (hydroxy{ (2S) -1-[N- (1-hydroxyethylidene) -L-norleucyl]-2-pyrrolidinyl}methylene) amino]hexylidene}amino) -4-[ (4-methyl-2-oxo-2H-chromen-7-yl) imino]butanoic acid. Grades: ≥98%. CAS No. 355140-49-7. Molecular formula: C33H45N5O9. Mole weight: 655.74.
Ac-Octreotide
Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2?7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Acoforestinine
Heterocyclic Organic Compound. Alternative Names: 8-O-Ethylyunaconitine. CAS No. 110011-77-3. Mole weight: 645.8. Purity: 90%+. Catalog: ACM110011773.
Aco I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA(dam-, dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with acoi more than 90% of lambda dna fragments can be ligated with t4 dna ligase at 16°c and recut. Group: Restriction Enzymes. Y↑GGCCR RCCGG↓Y. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1011EN.
Acolbifene
Acolbifene (EM-652), the active metabolite of EM800, is an orally active pure antiestrogen and selective estrogen receptor antagonist. Acolbifene (EM-652) inhibits estradiol (E2)-induced transcriptional activity of ERα (IC 50 = 2 nM) and ERβ (IC 50 = 0.4 nM). Acolbifene (EM-652) possesses potent and pure anticarcinogenic properties [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EM-652; SCH 57068. CAS No. 182167-02-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16023A.
Acolbifene
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 is the compound having the highest affinity for the estrogen receptor, including estradiol. It has higher affinity for the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells. Synonyms: EM-652; SCH 57068; (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol. Grades: ≥98%. CAS No. 182167-02-8. Molecular formula: C29H31NO4. Mole weight: 457.57.
Acolbifene hydrochloride
Acolbifene (EM-652) hydrochloride, an active metabolite of EM800, is an orally active, cancer-preventing selective estrogen receptor modulator (SERM). Acolbifene (EM-652) hydrochloride inhibits estradiol (E2)-induced transcriptional activity of ERα (IC 50 =2 nM) and ERβ (IC 50 =0.4 nM). Acolbifene (EM-652) hydrochloride exerts a potent and pure antiestrogenic action in the mammary gland and uterus. Anticarcinogenic properties [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EM-652 hydrochloride; SCH 57068 hydrochloride. CAS No. 252555-01-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16023.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.6. CAS No. 9025-1-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4806; aconitate decarboxylase; EC 4.1.1.6; 9025-01-8; cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase. Cat No: EXWM-4806.
aconitate Δ-isomerase
cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. This isomerization could take place either in a direct cis-trans interconversion or by an allylic rearrangement; the enzyme has been shown to catalyse the latter change. Group: Enzymes. Synonyms: aconitate isomerase. Enzyme Commission Number: EC 5.3.3.7. CAS No. 37318-48-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5504; aconitate Δ-isomerase; EC 5.3.3.7; 37318-48-2; aconitate isomerase. Cat No: EXWM-5504.
aconitate hydratase
Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. An iron-sulfur protein, containing a [4Fe-4S] cluster to which the substrate binds. Group: Enzymes. Synonyms: cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Enzyme Commission Number: EC 4.2.1.3. CAS No. 9024-25-3. Aconitase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5020; aconitate hydratase; EC 4.2.1.3; 9024-25-3; cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Cat No: EXWM-5020.
Aconitic acid
Aconitic acid (NSC 7616) is an organic acid, and can be isolated from seeds of Brassica oleracea var. acephala (kale). Aconitic acid has antifungal activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 7616. CAS No. 499-12-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W016814A.
Neurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In cultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization. Group: Biochemicals. Alternative Names: (1α, 3α, 6α, 14α, 15α, 16 β ) -20-Ethyl-1, 6, 16-trimethoxy-4- (methoxymethyl) aconitane-3, 8, 13, 14, 15-pentol 8-Acetate 14-Benzoate. Grades: Highly Purified. CAS No. 302-27-2. Pack Sizes: 10mg. US Biological Life Sciences.