A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Acid Dyes. Alternative Names: C.I. Acid Yellow 118. CAS No. 12270-05-2. Catalog: ACM12270052.
Acid Yellow 119
Heterocyclic Organic Compound. Alternative Names: C.I. Acid Yellow 119;Yellow 4R. CAS No. 12220-76-7. Catalog: ACM12220767.
Acid yellow 155
Heterocyclic Organic Compound. CAS No. 12220-81-4. Catalog: ACM12220814.
Acid Yellow 156
Heterocyclic Organic Compound. Alternative Names: Acid Yellow 156. CAS No. 12220-82-5. Catalog: ACM12220825.
acid yellow 158
Heterocyclic Organic Compound. Alternative Names: Acid Yellow 158. CAS No. 12220-84-7. Catalog: ACM12220847.
acid yellow 159
Heterocyclic Organic Compound. Alternative Names: C.I. Acid Yellow 159. CAS No. 12235-22-2. Catalog: ACM12235222.
Acid Yellow 17, Technical grade
Acid Yellow 17, Technical grade. Group: Biochemicals. Grades: Purified. CAS No. 6359-98-4. Pack Sizes: 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Acid yellow 246
Heterocyclic Organic Compound. CAS No. 119822-74-1. Catalog: ACM119822741.
Acid Yellow 3
Acid Yellow 3 is used in lipstick, lotion, soap, shampoo, bubble bath, oral medicine and applied drug application. Synonyms: C.I. Acid Yellow 3; 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline, sulfonated; Acid Yellow QS; Basacid Yellow 094; Basovit Yellow 095E; C.I. 47005; C.I. Food Yellow 13; Cogilor Yellow 112.12; D and C Yellow No. 10; D&C Yellow No. 10; D&C Yellow No. 10W074; Dye Quinoline Yellow; E 104; E 104 (dye); Eurocert Quinoline Yellow 311744; FD and C Yellow No. 10; FD&C Yellow No. 10; Food Yellow No. 13; Japan Yellow 203; Lemon Yellow ZN 3; Neelicol Quinoline Yellow WS; Puricolor Yellow FYE 13; Quinidine Yellow KT; Quinoline Yellow; Quinoline Yellow 36012; Quinoline Yellow 38009; Quinoline Yellow 90125; Quinoline Yellow 90145; Quinoline Yellow Certifiable 307006; Quinoline Yellow E 104; Quinoline Yellow Extra; Quinoline Yellow Lake; Quinoline Yellow S; Quinoline Yellow WG-G; Quinoline Yellow WG-G conc; Quinoline Yellow WS; Quinolone Yellow Extra; Vitasyn Quinoline Yellow 70; Yellow 10; Yellow No. 10; Yellow No. 203. CAS No. 8004-92-0.
Acid Yellow 3, C.I.
Acid Yellow 3, C.I. Group: Biochemicals. Grades: Highly Purified. CAS No. 8004-92-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C18H9NNa2O8S2. US Biological Life Sciences.
Worldwide
Acid Yellow 49
C.I. Acid Yellow 49, also known as C.I. 47005, is an azo dye with a bright yellow color. It is used as a dye in various industries, such as the food and textile industries, and has been used in scientific research to study various biochemical and physiological effects. Uses: C.i. acid yellow 49 acid yellow 49 has been used in scientific research to study a variety of biochemical and physiological effects. for example, it has been used to study the effects of oxidative stress on cells, as well as the effects of various drugs on cells. it has also been used to study the effects of environmental contaminants on cells, including the effects of heavy metals and organic pollutants. Group: Acid dyes. Alternative Names: C.I. Acid Yellow 49;Benzenesulfonic acid, 4-((5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)azo)-2,5-dichloro-. CAS No. 12239-15-5. Molecular formula: C16H13Cl2N5O3S. Mole weight: 426.28. Appearance: Powder. IUPACName: 4-[(5-amino-3-methyl-1-phenylpyrazol-4-yl)diazenyl]-2,5-dichlorobenzenesulfonic acid. Canonical SMILES: CC1=NN (C (=C1N=NC2=CC (=C (C=C2Cl)S (=O) (=O)O)Cl)N)C3=CC=CC=C3. Density: 1.6±0.1 g/mL. ECNumber: 235-473-4. Catalog: ACM12239155-2.
Acid Yellow 99. Alternative Names: Acid complex yellow GR. CAS No. 10343-58-5. Molecular formula: C16H13CrN4NaO8S. Mole weight: 496.35. Appearance: Yellow to brown powder. Purity: 0.4. Catalog: ACM10343585.
Ac-IEPD-AFC
Ac-IEPD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 1135417-31-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-IEPD-AFC
Ac-IEPD-AFC is a peptide whose sequence is preferred recognition motif for the serine protease granzyme B. It is a fluorogenic substrate. Synonyms: IEPD; N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin); Ac-Ile-Glu-Pro-Asp-7-Amino-4-trifluoromethylcoumarin. Grades: ≥95%. CAS No. 1135417-31-0. Molecular formula: C32H38F3N5O11. Mole weight: 725.67.
Ac-IETD-AFC
Ac-IETD-AFC is a fluorogenic substrate for caspase-8 and caspase-3. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 211990-57-7. Molecular formula: C31H38F3N5O12. Mole weight: 729.7.
Ac-IETD-CHO trifluoroacetate salt
Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM). It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 μM. Synonyms: Ac-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor. Grades: ≥95%. CAS No. 191338-86-0. Molecular formula: C21H34N4O10·xCF3COOH. Mole weight: 502.52.
Acifluorfen
Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50594-66-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-128075.
Acifran
Acifran. Group: Biochemicals. Grades: Purified. CAS No. 72420-38-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Acifran
Acifran is a nicotinic acid receptor agonist with hypolipidemic effects, which shows higher potency than nicotinic acid and clofibrate. It is a potent and full agonist at the human orphan GPCR HM74A/GPR109A and GPR109B. It reduces circulating LDL-cholesterol and serum triglycerides in vivo without affecting liver enzymes or liver weight. Synonyms: AY 25712; AY-25712; AY25712; 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid; (±)-Acifran; Reductol. Grades: ≥99% by HPLC. CAS No. 72420-38-3. Molecular formula: C12H10O4. Mole weight: 218.21.
Acifran
Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AY 25712. CAS No. 72420-38-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107579.
Acimox impurity 1
Acimox impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H16N2O. Mole Weight: 132.21. Catalog: APB10975.
Acimox impurity 2
Acimox impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C6H12N2. Mole Weight: 112.18. Catalog: APB10976.
Acimox impurity 3
Acimox impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2101955-01-3. Molecular Formula: C6H10N2. Mole Weight: 110.16. Catalog: APB2101955013.
Acimox impurity 4
Acimox impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 79068-45-4. Molecular Formula: C6H8N2O2. Mole Weight: 140.14. Catalog: APB79068454.
Acimox impurity 5
Acimox impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1378839-68-9. Molecular Formula: C6H6N2O3. Mole Weight: 154.13. Catalog: APB1378839689.
Acimox impurity 6
Acimox impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 77666-94-5. Molecular Formula: C6H4N2O2. Mole Weight: 136.11. Catalog: APB77666945.
Acimox impurity 7
Acimox impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1368358-42-2. Molecular Formula: C6H4N2O3. Mole Weight: 152.11. Catalog: APB1368358422.
Acimox impurity 8
Acimox impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2734844-49-4. Molecular Formula: C6H6N2O4. Mole Weight: 170.12. Catalog: APB2734844494.
Acipimox
Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-9321. CAS No. 51037-30-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0283.
Acipimox
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion ofVLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol. Synonyms: Acipimox; K-9321; K9321; K 9321; Olbemox; Olbetam. Grades: >98%. CAS No. 51037-30-0. Molecular formula: C6H6N2O3. Mole weight: 154.12.
Acipimox
Acipimox. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-carboxy-2-methylpyrazine 1-oxide. CAS No. 51037-30-0. Molecular Formula: C6H6N2O3. Mole Weight: 154.12. Catalog: APB51037300.
Acipimox
Antilipemic. Group: Biochemicals. Alternative Names: 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide; 5- methyl pyrazinecarboxylic Acid 4-Oxide; K 9321; Olbemox; Olbetam. Grades: Highly Purified. CAS No. 51037-30-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Acipimox-[13C2,15N2]
Acipimox-[13C2,15N2] is the labelled analogue of Acipimox, which is a niacin derivative used as a hypolipidemic agent. Synonyms: Acipimox-13C2,15N2; 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-13C2,15N2; 5-Methylpyrazinecarboxylic Acid 4-Oxide-13C2,15N2; Olbemox-13C2,15N2; Olbetam-13C2,15N2. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. Molecular formula: C4[13C]2H6[15N]2O3. Mole weight: 158.10.
Acipimox Impurity 1
Acipimox Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-carboxy-5-methylpyrazine 1,4-dioxide. Molecular Formula: C6H6N2O4. Mole Weight: 170.12. Catalog: APB03244.
Acipimox Impurity 2
Acipimox Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-methylpyrazine 1,4-dioxide. CAS No. 32046-26-7. Molecular Formula: C5H6N2O2. Mole Weight: 126.11. Catalog: APB32046267.
Acipimox Impurity 3
Acipimox Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-carboxy-5-methylpyrazine 1-oxide. CAS No. 51037-31-1. Molecular Formula: C6H6N2O3. Mole Weight: 154.12. Catalog: APB51037311.
Acipimox Impurity 4
Acipimox Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-carboxy-5-methylpyrazine 1-oxide. CAS No. 98502-96-6. Molecular Formula: C6H6N2O3. Mole Weight: 154.12. Catalog: APB98502966.
acireductone dioxygenase [iron(II)-requiring]
Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Enzyme Commission Number: EC 1.13.11.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0573; acireductone dioxygenase [iron(II)-requiring]; EC 1.13.11.54; ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Cat No: EXWM-0573.
acireductone dioxygenase (Ni2+-requiring)
Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Enzyme Commission Number: EC 1.13.11.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0572; acireductone dioxygenase (Ni2+-requiring); EC 1.13.11.53; ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Cat No: EXWM-0572.
acireductone synthase
This bifunctional enzyme first enolizes the substrate to form the intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one. The acireductone represents a branch point in the methione-salvage pathway as it is used in the formation of formate, CO and 3-(methylthio)propanoate by EC 1.13.11.53 [acireductone dioxygenase (Ni2+-requiring)] and of formate and 4-methylthio-2-oxobutanoate either by a spontaneous reaction under aerobic conditions or by EC 1.13.11.54 {acireductone dioxygenase [iron(II)-requiring]}. Group: Enzymes. Synonyms: E1; E-1 enolase-phosphatase. Enzyme Commission Number: EC 3.1.3.77. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3682; acireductone synthase; EC 3.1.3.77; E1; E-1 enolase-phosphatase. Cat No: EXWM-3682.
Acitretin
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimers disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 10-1670. CAS No. 55079-83-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0107.
Acitretin
Acitretin is a second generation retinoid used for psoriasis. Synonyms: Ro 10-1670; Ro-10-1670; Ro10-1670; Ro 10-1670/000; U0279; Acitretin; Soriatane; Etretin; Neotigason. Grades: >98%. CAS No. 55079-83-9. Molecular formula: C21H26O3. Mole weight: 326.43.
Acitretin
Acitretin. Group: Biochemicals. Alternative Names: 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Grades: Highly Purified. CAS No. 55079-83-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C21H26O3. US Biological Life Sciences.
A synthetic retinoid which is the major metabolite of etretinate. Group: Biochemicals. Alternative Names: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid; Neotigason, Soriatane. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Acitretin EP Impurity A (Acitretin USP Related Compound A, 13-cis-Acitretin)
Acitretin EP Impurity A (Acitretin USP Related Compound A, 13-cis-Acitretin). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. CAS No. 69427-46-9. Molecular Formula: C21H26O3. Mole Weight: 326.44. Catalog: APB69427469.
Acitretin Glucuronide
Acitretin Glucuronide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(((2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoyl)oxy)tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 99792-36-6. Molecular Formula: C27H34O9. Mole Weight: 502.57. Catalog: APB99792366.
Acitretin impurity 1
Acitretin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H34O9. Mole Weight: 502.56. Catalog: APB10174.
Acitretin Impurity 1
Acitretin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2E,4E,6E,8E)-isopropyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate. CAS No. 74479-46-2. Molecular Formula: C24H32O3. Mole Weight: 368.52. Catalog: APB74479462.
Acitretin Impurity 10
Acitretin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2E,4E,6E,8E)-3-ethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-7-methylnona-2,4,6,8-tetraenoic acid. Molecular Formula: C22H28O3. Mole Weight: 340.46. Catalog: APB03236.
Acitretin Impurity 11
Acitretin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2E,4E,6E,8E)-butyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate. CAS No. 74479-40-6. Molecular Formula: C25H34O3. Mole Weight: 382.54. Catalog: APB74479406.
Acitretin Impurity 2
Acitretin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,4'-((1E,3E,5E,7E,9E)-3,8-dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene). CAS No. 1621284-00-1. Molecular Formula: C32H40O2. Mole Weight: 456.67. Catalog: APB1621284001.
Acitretin Impurity 3
Acitretin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,4'-((1E,3E,5Z,7E,9E)-3,8-dimethyldeca-1,3,5,7,9-pentaene-1,10-diyl)bis(1-methoxy-2,3,5-trimethylbenzene). Molecular Formula: C32H40O2. Mole Weight: 456.67. Catalog: APB03128.
Acitretin Impurity 4
Acitretin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2Z,4E,6E,8E)-9-(3-(hydroxymethyl)-4-methoxy-2,6-dimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Molecular Formula: C21H26O4. Mole Weight: 342.44. Catalog: APB03238.
Acitretin sodium
Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent. Synonyms: Ro 10-1670 sodium; Soriatane sodium. Grades: >98%. CAS No. 925701-88-8. Molecular formula: C21H25NaO3. Mole weight: 348.41.
Acivicin
Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Synonyms: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grades: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57.
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125; U-42126. CAS No. 42228-92-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W016586.
Acivicin
Azaserine and Acivicin are classical and irreversible inhibitors of γ -Glutamyl transpeptidase. Group: Biochemicals. Alternative Names: (αS,5S)-. Grades: Highly Purified. CAS No. 42228-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties. Group: Inhibitors. Alternative Names: (alpha-s, 5s)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleaceticacid; (s-(r*, r*))-4, 5-dihydro-alpha-amino-3-chloro-5-isoxazoleaceticacid; 4, 5-dihydro-alpha-amino-3-chloro-, (s-(r*, r*))-5-isoxazoleaceticaci; acivicine; antibioticat125; nsc-163501; AT-125; ALPHA-AMINO-3-CHLORO-4, 5-DIHYDRO-5-ISOXAZOLEACETIC ACID. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57. Appearance: Solid. Canonical SMILES: ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1. Catalog: ACM42228922.
Acivicin hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A.
A cell-permeable furopyrimidine that acts as a potent, ATP-binding site-targeting, Ack1-selective inhibitor (IC50 = 22nM) and effectively prevents receptor-mediated Ack1 activation (by >90% in MEF & LAPC4 cultures; 16h 800nM), while exhibiting much reduced potency against Lyn, Lck, Abl1 and BTK (IC50 ≥346.7nM) and no inhibitory activity toward 25 other kinases. Shown to completely inhibit EGF-induced, but not androgen DHT- (dihydrotestosterone) stimulated, AR transcription activity in serum- and androgen-deprived prostate cancer LAPC4 cutlures. Effectively inhibits androgen-independent LNCaP prostate cancer growth both in vitro (by 60%; 72h 8uM) and in castrated mice in vivo (4mg/kg/96h injections on day 7/11/15/19/23/27 post tumor transplant). Group: Biochemicals. Grades: Highly Purified. CAS No. 873305-35-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Aclacinomycin A
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Aclarubicin. CAS No. 57576-44-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2306.
aclacinomycin-A oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A (cf. EC 1.1.3.45) and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y. Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.3.3.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1375; aclacinomycin-A oxidase; EC 1.3.3.14; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-1375.