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| Product | Description | |
|---|---|---|
| BmKn2 | BmKn2 was found in Mesobuthus martensii. BmKn2 has strong antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, P.aeruginosa and N.gonorrhoeae. BmKn2 also shows low activity against HIV-1 PV. |  |
| BML 111 | BML 111 is a FPR2 (lipoxin A4 receptor) agonist. It inhibits tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. BML 111 also protects against hemorrhagic shock-induced acute lung injury in rats and attenuates renal ischemia/reperfusion injury. Synonyms: BML-111; BML 111; BML111. (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate; methyl (5S,6R)-5,6,7-trihydroxyheptanoate. CAS No. 78606-80-1. Molecular formula: C8H16O5. Mole weight: 192.21. | |
| BML-190 | BML-190. Group: Biochemicals. Grades: Purified. CAS No. 2854-32-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BML-210 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| BML-210 | BML-210 is a Histone deacetylase (HDAC) inhibitor (IC50 = 87 μM), inducingchanges in gene expression profile. Uses: A histone deacetylase (hdac) inhibitor. Synonyms: BML-210; BML 210; BML210; CAY10433; CAY-10433; CAY 10433N1-(2-aminophenyl)-N8-phenyloctanediamide; N-(2-aminophenyl)-N'-phenyl-octanediamide. Grade: ≥98%. CAS No. 537034-17-6. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
| BML-210 | BML-210, also known as CAY10433, is HDAC inhibitor. BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells. BML-210 can inhibit cell growth and induce apoptosis in cervical cancer cells, what correlates with down-regulation of HDAC class I and II and changes in the DAPC expression levels. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BML-210; BML 210; BML210; CAY10433; CAY-10433; CAY 10433. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 537034-17-6. Molecular formula: C20H25N3O2. Mole weight: 339.44. Purity: >98%. IUPACName: N-(2-aminophenyl)-N'-phenyl-octanediamide. Canonical SMILES: O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O. Product ID: ACM537034176. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BML-210, HDAC Inhibitor (N1-(2-aminophenyl)-N8-. phenyloctanediamide) | A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10uM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. Group: Biochemicals. Alternative Names: N1-(2-aminophenyl)-N8-phenyloctanediamide. Grades: Highly Purified. CAS No. 537034-17-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| BML-244 | BML-244 is a potent cathespin K inhibitor. Synonyms: BML 244; BML244; (1-formyl-pentyl)-carbamic acid tert-butyl ester; 2-[(tert-Butyloxycarbonyl)amino]hexanal. Grade: 98%. CAS No. 104062-70-6. Molecular formula: C11H21NO3. Mole weight: 215.29. | |
| Bml-259 | BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 267654-00-2. Molecular formula: C14H16N2OS. Mole weight: 260.4. Purity: >98%. IUPACName: 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide. Canonical SMILES: O=C(NC1=NC=C(C(C)C)S1)CC2=CC=CC=C2. Product ID: ACM267654002. Alfa Chemistry ISO 9001:2015 Certified. | |
| BML 264 | BML 264 is a TPR channel blocker and phospholipase A2 (PLA2) inhibitor. It blocks the receptor-induced release of arachidonic acid and subsequent signaling cascades in the pancreas and the cardiovascular system. Synonyms: Benzoic acid, 2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-; 2-[[(2E)-1-Oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]benzoic acid; Benzoic acid, 2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propenyl]amino]-; Benzoic acid, 2-[[1-oxo-3-(4-pentylphenyl)-2-propenyl]amino]-, (E)-; (E)-2-(3-(4-pentylphenyl)acrylamido)benzoic acid; BML264; BML-264. Grade: ≥95%. CAS No. 99196-74-4. Molecular formula: C21H23NO3. Mole weight: 337.41. | |
| BML-277 | BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Synonyms: BML-277; BML 277; BML277; Chk2 Inhibitor II; 2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide. Grade: ≥98%. CAS No. 516480-79-8. Molecular formula: C20H14ClN3O2. Mole weight: 363.80. | |
| BML-277 | BML-277 is a selective checkpoint kinase 2 (Chk2) inhibitor with an IC50 of 15 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chk2 Inhibitor II. CAS No. 516480-79-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13946. |  |
| BML-278 | BML-278 is a SIRT1 activator ( EC 150 : 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120533-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W025074. | |
| BML-278 | BML-278 is a selective Sirt1 activator (EC150 = 1μM) structurally based on a dihydropyridine scaffold. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. Synonyms: BML 278; BML278. Grade: ≥95%. CAS No. 120533-76-8. Molecular formula: C24H25NO4. Mole weight: 391.5. | |
| BML-278, SIRT1 Inhibitor (N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine) | A structurally novel activator of SIRT1 (EC150=1uM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50uM respectively). Cell permeable. Group: Biochemicals. Alternative Names: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| BML-284 | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Synonyms: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. Grade: >98%. CAS No. 853220-52-7. Molecular formula: C19H18N4O3. Mole weight: 350.37. | |
| BML-284 | BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 853220-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19987. | |
| BML-286 | A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways. Group: Biochemicals. Alternative Names: 2- [ [3- [ (2-phenylacetyl) amino] benzoyl] amino] benzoic Acid; 2- [ [3- [ (phenylacetyl) amino] benzoyl] amino] benzoic Acid. Grades: Highly Purified. CAS No. 294891-81-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BML-287 | BML-287 is a selective inhibitor of secreted frizzled related protein-1 (sFRP-1). BML-287 is a useful tool for studying the Wnt signaling pathway. Group: Biochemicals. Alternative Names: N-[2- (3, 4-Dimethoxyphenyl) ethyl]-2-ethyl-5- (phenylsulfonyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 915754-05-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BML-288 | BML-288. Group: Biochemicals. Alternative Names: 6,7-Dihydro-5-methyl-6-oxo-N-1,3,4-thiadiazol-2-yl-5H-furo[2,3-f]indole-7-carboxamide. Grades: Highly Purified. CAS No. 851681-89-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H10N4O3S. US Biological Life Sciences. | Worldwide |
| BMMCC | BMMCC. Pack Sizes: Milligram Quantities: 50 mg. Order Number: B111. |  www.prochemonline.com |
| BMN-673 8R,9S | BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP inhibitor BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability and eventually leads to apoptosis. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and is activated by single-strand DNA breaks. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Synonyms: Talazoparib (8R,9S); (8R,9S)-BMN-673; BMN673 (8R,9S); BMN 673 (8R,9S). Grade: >98%. CAS No. 1207456-00-5. Molecular formula: C19H14F2N6O. Mole weight: 380.35. | |
| BMP | Dimethyl (2-Oxo-4-phenylbutyl)phosphonate is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Alternative Names: Dimethyl (2-oxo-4-phenylbutyl)phosphonate. Dimethyl 2-Oxo-4-phenylbutylphosphonate. 1-dimethoxyphosphoryl-4-phenylbutan-2-one. Phosphonic acid, (2-oxo-4-phenylbutyl)-, dimethyl ester. CAS No. 41162-19-0. Product ID: INT41162190. Molecular formula: C12H17O4P. Mole weight: 256.23. EINECS: 682-093-3. SMILES: COP(=O)(CC(=O)CCC1=CC=CC=C1)OC. Appearance: Clear Light Yellow Oil. Application: Bimatoprost & Latanoprost Intermediates. Category: Intermediates. |  |
| BMP-10 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-11 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-12/GDF-7 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-13 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-14 (GDF-5/CDMP-1) human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-22 | BMP-22 is an inhibitor of autotaxin with IC50 of 170 nM. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) in vitro in a concentration-dependent manner. MP-22 can decrease the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis. Synonyms: 4-pentadecylbenzylphosphonic acid; BMP22; BMP 22. Grade: ≥95%. CAS No. 1306684-90-1. Molecular formula: C22H39O3P. Mole weight: 382.52. | |
| BMP-2 Epitope (73-92) | BMP-2 Epitope (73-92) is the 73-92 amino acid residue of the knuckle epitope of bone morphogenetic protein-2 (BMP-2). BMP-2 promotes the formation and regeneration of bone and cartilage, and also participates in organogenesis, cell differentiation, cell proliferation, and apoptosis. Synonyms: BMP-2 Knuckle Epitope (73-92); H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-OH; L-lysyl-L-isoleucyl-L-prolyl-L-lysyl-L-alanyl-L-seryl-L-seryl-L-valyl-L-prolyl-L-threonyl-L-alpha-glutamyl-L-leucyl-L-seryl-L-alanyl-L-isoleucyl-L-seryl-L-threonyl-L-leucyl-L-tyrosyl-L-leucine. CAS No. 500719-13-1. Molecular formula: C97H164N22O30. Mole weight: 2118.5. | |
| BMP-3 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMP-4 human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| BMP Inhibitor II, DMH1 (ALK2/3 Inhibitor, DMH1, Bone Morphogenetic Protein Inhibitor, DMH1, 4- (6- (4-Isopropoxyphenyl) pyrazolo[1, 5-a]pyrimidin-3-yl) quinoline) | A cell-permeable pyrrazolopyrimidine compound that inhibits against R/VEGFR2, ALK2/BMPR-I, AMPK kinase activity (IC50=25.1, 148, and 234.6nM, respectively), while exhibiting much reduced or little effect toward ALK5/TGFbR-I, ZAPK, Syk, PKCth, PKA, or JAK3. Shown to block both BMP pathway-dependent dorsoventral development (EC100=2.5uM) and VEGF signaling-dependent intersomitic vessel formation (EC50=5uM) in zebrafish embryo in vivo. Commonly used in combination with AMPK activators AICAR and/or Metformin for studying AMPK-dependent cellular events in vitro and physiological responses in animals in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206711-16-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline) | A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
| BMPO | BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BocMPO. CAS No. 387334-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121137. | |
| BMPR1A human | recombinant, expressed in Insect cells (Baculovirus), ?90% (SDS-PAGE), ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMPR2 (174-end), active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. | |
| BMP signaling agonist sb4 | BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding,?Id1?and?Id3) canonical BMP signaling[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100874-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124697. | |
| BmPyPhB | BmPyPhB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis[3,5-di(pyridin-3-yl)phenyl]benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1030380-38-1. Molecular formula: C38H26N4. Mole weight: 538.64 g/mol. Product ID: ACM1030380381. Alfa Chemistry ISO 9001:2015 Certified. | |
| BMS-002 | BMS-002 is a selective antogonist of lysophosphatidic acid (LPA) receptor-1 developed to treat diabetic nephropathy. In eNOS-/- db/db mouse model, BMS-002 significantly decreased the level of proteinuria. Uses: The potential treatment of diabetic nephropathy. Synonyms: BMS 002; BMS002. | |
| BMS-066 | BMS-066 is an inhibitor of IKKβ/Tyk2 pseudokinase, with IC50s of 9 and 72 nM, respectively. Synonyms: 2-Methoxy-N-((6-(1-methyl-4-(methylamino)-1,5-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide; Acetamide, N-((6-(1,6-dihydro-1-methyl-4-(methylamino)imidazo(4,5-d)pyrrolo(2,3-b)pyridin-7-yl)-2-pyridinyl)methyl)-2-methoxy-; N-((6-(1,6-Dihydro-1-methyl-4-(methylamino)imidazo(4,5-d)pyrrolo(2,3-b)pyridin-7-yl)-2-pyridinyl)methyl)-2-methoxyacetamide. Grade: ≥95%. CAS No. 914946-88-6. Molecular formula: C19H21N7O2. Mole weight: 379.42. | |
| BMS-1 | BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction (IC50 between 6 and 100 nM)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-1/PD-L1 inhibitor 1. CAS No. 1675201-83-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19991. | |
| BMS-1001 | BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with IC50 of 2.25 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Synonyms: BMS 1001; BMS1001. CAS No. 2113650-03-4. Molecular formula: C35H34N2O7. Mole weight: 594.65. | |
| BMS-1001 hydrochloride | BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with IC50 of 2.25 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Synonyms: BMS-1001 HCl; (2-((3-Cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride. Grade: 98%. CAS No. 2113650-04-5. Molecular formula: C35H35ClN2O7. Mole weight: 631.12. | |
| BMS-1166 | BMS-1166 is a novel and potent inhibitor of the PD-1/PD-L1 interaction with IC50 of 1.4 nM. Synonyms: BMS1166; BMS 1166. CAS No. 1818314-88-3. Molecular formula: C36H33ClN2O7. Mole weight: 641.11. | |
| BMS-1166 | BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818314-88-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102011. | |
| BMS-180048 | BMS-180048, also know as Avitriptan Fumarate, has been found to be a5HT-1B/1D-receptor agonist that was once studied as an anti-migraine agent. Synonyms: Avitriptan Fumarate; BMS 180048; BMS-180048; BMS180048; UNII-2G25KE3954; 3-(3-(4--(5-methoxy-4-pyrimidinyl)-1-piperazinyl)propyl)-N-methyl-1H-indole-5-methanesulfonamide fumarate. Grade: 98%. CAS No. 171171-42-9. Molecular formula: C26H34N6O7S. Mole weight: 574.65. | |
| BMS 180448 | BMS 180448 is a prototype mitochondrial ATP-sensitive K+ channel stimulant. The cardioprotective effects of BMS-180448 against I/R heart injury may result from direct activation of mitoK(ATP) channel in cardiomyocytes. In Sep 2003, Phase-II for Myocardial ischaemia in USA was discontinued. Uses: Myocardial ischaemia. Synonyms: BMS 180448; BMS-180448; BMS180448; trans-N-(4-chlorophenyl)-N'-cyano-N''-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)- Guanidine. Grade: 98%. CAS No. 144264-47-1. Molecular formula: C20H18ClN5O2. Mole weight: 395.85. | |
| BMS 180680 | BMS 180680 is antibacterial activity agent of new catechol-containing monobactam. It is a cell wall inhibitor. BMS-180680 is an active compound against many species of the family Enterobacteriaceae, with MICs at which 90% of the isolates were inhibited. In Oct 2002, Phase-II for Respiratory tract infections in USA was discontinued. Uses: Respiratory tract infections. Synonyms: BMS 180680; BMS180680; BMS-180680; SQ 84,100; (2R-(2alpha,3alpha(Z)))-3-((((1-(2-Amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)methyl)-6,7-dihydroxy-2-quinoxalinecarboxylic acid. Grade: 98%. CAS No. 142654-34-0. Molecular formula: C19H17N7O10S2. Mole weight: 567.51. | |
| BMS 181101 | BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin reuptake at some extent. It has already been discontinued by Bristol-Myers Squibb. Synonyms: BMS 181101; BMS181101; BMS-181101; AC1L42ZR; SCHEMBL4356376; DTXSID40163380; 5-fluoro-3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indole Dihydrochloride. Grade: 98%. CAS No. 146479-45-0. Molecular formula: C20H26Cl2FN5O. Mole weight: 442.36. | |
| BMS 181168 | This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropic agent and it can protect rodents from ECS-induced amnesia in a step-down passive avoidance task. But clinical study for treatment of Alzheimer's disease was discontinued. Uses: Alzheimer's disease. Synonyms: Bmy 21502; Bmy21502; Bmy-21502; Bms-181168; Bms 181168; Bms181168. 1-((1-(2-(trifluoromethyl)pyrimidin-4-yl)piperidin-4-yl)methyl)pyrrolidin-2-one. Grade: 98%. CAS No. 123259-91-6. Molecular formula: C15H19F3N4O. Mole weight: 328.34. | |
| BMS-181184 | BMS-181184 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton. Synonyms: D-Serine, N-((5-((6-deoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo(a)naphthacen-2-yl)carbonyl)-, (5S-trans)-. CAS No. 139272-69-8. Molecular formula: C39H41NO20. Mole weight: 843.74. | |
| BMS-181532 | BMS-181532 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton. Synonyms: BMS 181532. CAS No. 146877-08-9. Molecular formula: C34H33NO16. Mole weight: 711.62. | |
| BMS 182264 | BMS 182264 is a bio-active chemical, but few detailed information has been published yet. Synonyms: BMS 182264; BMS-182264; BMS182264; CHEMBL19169; N-Cyano-N'-(4-cyanophenyl)-N''-1,2,2-trimethylpropylguanidine. Grade: 98%. CAS No. 127749-54-6. Molecular formula: C15H19N5. Mole weight: 269.35. | |
| BMS 182874 | BMS 182874 is an endothelin receptor antagonist used as an antihypertensive agent. Uses: Antihypertensive agents. Synonyms: 5-Ddins; BMS 182874; BMS-182874; BMS182874; CHEMBL267458; 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide. CAS No. 153042-42-3. Molecular formula: C17H19N3O3S. Mole weight: 345.417. | |
| BMS 182874 | BMS 182874 is an orallyactive, highly selective endothelin receptor ( ET A receptor) antagonist, with IC 50 value of 0.150 μM, K i of 0.055 μM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153042-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118497. | |
| BMS-182874 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS 182874 Hydrochloride | This active molecular is a selective non-peptide Endothelin ETA receptor antagonist. It displays more than 1000-fold selectivity over ETB receptors (Ki of 48 nM for ETA receptors and >50 μM for ETB). BMS 182874 displays ET-1 inhibitory efficacy in vivo and vitro and it also inhibits ET-1-induced longitudinal muscle contraction in vitro. In 2006, BMS 182874 for coronary disorders and hypertension were discontinued in USA. Uses: Coronary disorders and hypertension. Synonyms: BMS 182874; BMS-182874; BMS182874; BMS 182874 HCl; BMS 182874 hydrochloride; 5-(dimethylamino)-N-(3,4-dimethylisoxazol-5-yl)naphthalene-1-sulfonamide hydrochloride. Grade: 98%. CAS No. 1215703-04-0. Molecular formula: C17H20ClN3O3S. Mole weight: 381.88. | |
| BMS 183920 | BMS 183920, a quinoline derivative, has been found to be an angiotensin II receptor antagonist that could have potential usage in antihypertensive study. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: BMS 183920; BMS-183920; BMS183920; CHEMBL305365; 2-Cyclopropyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)oxy)-4-quinolinecarboxylic acid; 4-Quinolinecarboxylicacid, 2-cyclopropyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]oxy]-. Grade: 98%. CAS No. 153072-33-4. Molecular formula: C26H19N5O3. Mole weight: 449.47. | |
| BMS-186318 | BMS-186318 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 186318; BMS-186318; BMS186318; 12-Oxa-2,6,10-triazatetradecanoic acid, 4,8-dihydroxy-13,13-dimethyl-3-((4-(2-(4-morpholinyl)-2-oxoethoxy)phenyl)methyl)-11-oxo-9-(phenylmethyl)-, 1,1-dimethylethyl ester, (3S,4R,8R,9S)-; BMS-186318 analog 19; 12-Oxa-2,6,10-triazat. Grade: 98%. CAS No. 161302-40-5. Molecular formula: C36H54N4O9. Mole weight: 686.85. | |
| BMS-186511 | BMS-186511 is a Farnesyltransferase (FT) inhibitor with potential anticancer activity. Synonyms: BMS186511; BMS 186511; ((5S,8S,11S)-8,11-diisopropyl-5-(methoxycarbonyl)-7,10,13-trioxo-2-thia-6,9,12-triazapentadecan-15-yl)((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)phosphinic acid. Grade: >98%. CAS No. 167467-53-0. Molecular formula: C26H27N5O5. Mole weight: 685.90. | |
| BMS-187071 | BMS-187071 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 187071; BMS187071; BMS187071; (3-((3-((2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino)-2-hydroxy-4-phenylbutyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamic acid, 1,1-dimethylethyl ester; [3-[[3-[(2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino]-2-hydroxy-4. Grade: 98%. CAS No. 161302-39-2. Molecular formula: C32H49N3O6. Mole weight: 571.75. | |
| BMS-187308 | BMS-187308, a sulfonamide derivative, has been found to be an endothelin-A (ETA) antagonist that was once studied about its activity against pressor effect in rats. Synonyms: BMS-187308; BMS 187308; BMS187308; UNII-7K0YU35900; CHEMBL106684; 7K0YU35900; SCHEMBL6767698; BDBM50068674; 2-[2-amino-4-(2-methylpropyl)phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide. Grade: 98%. CAS No. 153624-15-8. Molecular formula: C21H25N3O3S. Mole weight: 399.51. | |
| BMS-188494 | BMS-188494 is the prodrug of BMS-187745, a squalene synthase inhibitor used as an anticholesterol drug. Synonyms: 1-[bis(2,2-dimethylpropanoyloxymethoxy)phosphoryl]-4-(3-phenoxyphenyl)butane-1-sulfonic acid; BMS-188494; BMS 188494; BMS188494; UNII-F4W2579G7P. Grade: >98%. CAS No. 191866-32-7. Molecular formula: C28H39O11PS. Mole weight: 614.645. | |
| Bms 188745 potassium salt | Bms 188745 potassium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (αS)-3-Phenoxy-α-phosphonobenzenebutanesulfonic Acid Tripotassium Salt. Product Category: Heterocyclic Organic Compound. CAS No. 157126-15-3. Molecular formula: C16H16K3O7PS. Mole weight: 500.63. Purity: 0.96. IUPACName: tripotassium;(1S)-4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate. Canonical SMILES: C1=CC=C(C=C1)OC2=CC=CC(=C2)CCCC(P(=O)([O-])[O-])S(=O)(=O)[O-].[K+].[K+].[K+]. Product ID: ACM157126153. Alfa Chemistry ISO 9001:2015 Certified. | |
| BMS 188745 potassium salt | BMS 188745 potassium salt. Group: Biochemicals. Alternative Names: (a-S) -3-Phenoxy-a-phosphono Benzene butanesulfonic acid tripotassium salt. Grades: Highly Purified. CAS No. 157126-15-3. Pack Sizes: 10mg. Molecular Formula: C16H16K3O7PS. US Biological Life Sciences. | Worldwide |
| BMS-189453 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BMS 191011 | BMS 191011. Group: Biochemicals. Grades: Purified. CAS No. 202821-81-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BMS 191011 | BMS 191011 is a potent opener of the large-conductance, Ca2+-activated potassium (maxi-K) channel. It is neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke). Synonyms: 3-[(5-chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-one; BMS-191011; BMS 191011; BMS191011; UNII-LW7MXS978N; Bms-a. Grade: >99 %. CAS No. 202821-81-6. Molecular formula: C16H10ClF3N3O3. Mole weight: 370.71. | |
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