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| Product | Description | |
|---|---|---|
| BPH-1358 mesylate | BPH-1358 mesylate is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. BPH-1358 mesylate is active against S. aureus in vitro (MIC ~250 ng/mL). Synonyms: NSC50460 mesylate. Molecular formula: C34H36N6O8S2. Mole weight: 720.82. |  |
| BPH-652 | BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections. Synonyms: BMS-187745; BPH-652; BMS 187745; BPH 652; BMS187745; BPH652; CHEMBL351151; BMS 188745 Potassium Salt; DNC009027; KB-75764; tripotassium; 4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate. Grade: 98%. CAS No. 157124-84-0. Molecular formula: C16H16K3O7PS. Mole weight: 500.63. | |
| BPH715 | BPH715 is a new generation of lipophilic bisphosphonates. It is potent in cell culture and effectively inhibited tumor cell growth and invasiveness. It is used as anticancer agents that block protein prenylation also have potent activity against Plasmodium liver stages. It has activity against a Plasmodium geranylgeranyl diphosphate synthase (GGPPS), as well as low nM activity against human farnesyl and geranylgeranyl diphosphate synthases. It is used to treat bone resorption diseases and has activity against a broad range of protists, including blood-stage Plasmodium spp. Uses: Bph715 is used as anticancer agents that block protein prenylation also have potent activity against plasmodium liver stages. it is also used to treat bone resorption diseases and has activity against a broad range of protists. Synonyms: BPH-715; BPH 715; BPH715; GTPL3196; GTPL 3196; GTPL-3196; Bisphpshonate-715. 3-(Decyloxy)-1-(2-hydrogen phosphonato-2-phosphonoethyl)pyridin-1-ium; Bisphpshonate-715; [2-(3-Decoxypyridin-1-ium-1-yl)-1-phosphonoethyl]-hydroxyphosphinate; Hydrogen (2-(3-(decyloxy)pyridin-1-ium-1-yl)-1-phosphonoethyl)phosphonate. Grade: >98%. CAS No. 1059677-23-4. Molecular formula: C17H31NO7P2. Mole weight: 423.38. | |
| BPHA | BPHA is a potent and orally active MMP-2 , MMP-9 and MMP-14 inhibitor with IC 50 s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC 50 s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193807-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114785. |  |
| Bphen | Bphen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 47-Diphenyl-110-phenanthroline. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1662-01-7. Molecular formula: C24H16N2. Mole weight: 332.4 g/mol. Product ID: ACM1662017-4. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,7-Diphenyl-1,10-phenanthroline, B-Phenethylamine. |  |
| B-Phycoerythrin, activated | BioReagent, suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy. |  |
| BPI-3016 | BPI-3016 is an analogue of human glucagon-like peptide 1 (hGLP-1) that has a long effect on type 2 diabetes mellitus. In vitro, BPI-3016 exhibited an affinity to GLP receptors and promotes cAMP production. In vivo, the half-life of BPI-3016 was 95h after single dosing in pharmacokinetic studies in diabetic cynomolgus monkey models. Uses: The treatment of type 2 diabetes. Synonyms: BPI-3016; BPI 3016; BPI3016. | |
| BPI-9016M | BPI-9016M is a potent, orally active, and selective dual c-Met and AXL tyrosine kinases inhibitor. BPI-9016M suppresses tumor cell growth, migration and invasion of lung adenocarcinoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1528546-94-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114356. | |
| BPI-9016M | BPI-9016M, a potent, orally active and selective dual c-Met and AXL tyrosine kinase inhibitor, inhibits lung adenocarcinoma tumor cell growth, migration and invasion. Synonyms: N-[4-(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1,4-dihydro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, N-[4-[(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo-. Grade: ≥95%. CAS No. 1528546-94-2. Molecular formula: C25H18F2N4O3. Mole weight: 460.43. | |
| bPiDDB | bPiDDB is a neuronal nicotinic acetylcholine receptor (AChR) antagonist with IC50s of 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1γδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors, respectively. Synonyms: Pyridinium, 1,1'-(1,12-dodecanediyl)bis[3-methyl-, bromide (1:2); Pyridinium, 1,1'-(1,12-dodecanediyl)bis[3-methyl-, dibromide; 1,1'-(1,12-Dodecanediyl)bis[3-methylpyridinium] dibromide; N,N'-Dodecylbis-Picolinium Bromide; N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide; 1,1'-(Dodecane-1,12-diyl)bis(3-methylpyridin-1-ium) bromide; BPiDDB. Grade: ≥95%. CAS No. 525596-66-1. Molecular formula: C24H38Br2N2. Mole weight: 514.38. | |
| bPiDDB | bPiDDB. Group: Biochemicals. Grades: Purified. CAS No. 525596-66-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| bPiDDB | bPiDDB is a potent nAChR antagonist. bPiDDB potently ( IC 50 =2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 525596-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107674. | |
| bPiDl hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BPIPP | BPIPP. Group: Biochemicals. Grades: Purified. CAS No. 325746-94-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BPIPP | BPIPP is a non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. It downregulates cAMP and cGMP synthesis, suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2 μM), inhibits GC-stimulated Cl- transport in vitro, and suppresses toxin-induced intestinal fluid accumulation in vivo. BPIPP may be a useful treatment of diarrhea. Uses: Potential treatment of diarrhea. Synonyms: 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione. Grade: ≥99% by HPLC. CAS No. 325746-94-9. Molecular formula: C22H16BrN3O3. Mole weight: 450.28. | |
| BPIQ-I | BPIQ-I is an extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) with IC50 of 25 pM. It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 μM, respectively. Uses: Protein kinase inhibitors. Synonyms: PD 159121. Grade: ≥95%. CAS No. 174709-30-9. Molecular formula: C16H12BrN5. Mole weight: 354.2. | |
| BPIQ-II hydrochloride | BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) with IC50 of 8 pM. It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR. Synonyms: PD 158294. Grade: ≥98%. CAS No. 171179-37-6. Molecular formula: C15H10BrN5·HCl. Mole weight: 376.6. | |
| BPK-25 | BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305052-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141550. | |
| BPK-29 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BPK-29 | BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. Synonyms: BPK 29; BPK29. Grade: 98% by HPLC. CAS No. 2143467-62-1. Molecular formula: C26H32ClN3O3. Mole weight: 470.0. | |
| BPKDi | BPKDi is an inhibitor of protein kinase D with IC50 of 1, 9, and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes and concomitantly suppresses hypertrophy of these cells. Synonyms: bipyridyl PKD inhibitor; 2'-(Cyclohexylamino)-6-(piperazin-1-yl)-2,4'-bipyridine-4-carboxamide. Grade: 99%. CAS No. 1201673-28-0. Molecular formula: C21H28N6O. Mole weight: 380.49. | |
| Bpl I, SAM, 50X | Bpl I, SAM, 50X. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 1x100ul. US Biological Life Sciences. | Worldwide |
| BpmI | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and 95% may be recut. Group: Restriction Enzymes. Purity: 50U; 250U. CTGGAG(N)16↑ GACCTC(N)14&darr. Activity: 500-1000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus pumilus. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1038RE. |  |
| BPMO | BPMO. Synonyms: PROPYLENE GLYCOL MONOOLEATE;EMALEX PGO;oleic acid, monoester with propane-1,2-diol;PROPYLENE GLYCOL OLEATE;9-Octadecenoic acid (9Z)-, monoester with 1,2-propanediol;9-OCTADECENOICACID,MONOESTERWITH1,2-PROPANEDIOL;9-Octadecenoic acid (Z)-, monoester with 1,2-propanediol 9-octadecenoic acid (z)-, monoester with1,2-propanediol 9-Octadecenoic acid(Z)-,monoester with 1,2-propanediol;Crill 25. CAS No. 1330-80-9. Product ID: CDF4-0103. Molecular formula: C21H40O3. Category: Food Emulsifiers. Product Keywords: Food Ingredients; Food Emulsifiers; BPMO; CDF4-0103; 1330-80-9; C21H40O3; 215-549-3; 1330-80-9. Purity: 0.99. EC Number: 215-549-3. Boiling Point: 176-183 °C(Press: 2 Torr). Density: 0.919[at 20°C]. |  |
| BPN-15606 besylate | BPN-15606 besylate is a highly potent and orally active γ-secretase modulator (GSM) with acceptable PK/PD properties, including bioavailability, half-life and clearance. It attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50s of 7 and 17 nM, respectively. It decreases the level of Aβ42 and Aβ40 in the central nervous system of rats and mice. Synonyms: N-[(1S)-1-(4-Fluorophenyl)ethyl]-6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-4-methyl-3-pyridazinamine benzenesulfonate (1:1); 3-Pyridazinamine, N-[(1S)-1-(4-fluorophenyl)ethyl]-6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-4-methyl-, benzenesulfonate (1:1). Molecular formula: C29H29FN6O4S. Mole weight: 576.64. | |
| BPO-27 racemate | BPO-27 racemate inhibited CFTR with IC50 ? 8 nM and had greatly improved in vitro metabolic stability and aqueous solubility compared to PPQ-102. Synonyms: BPO-27 (racemate); BPO 27 racemate; BPO27 racemate; BPO-27 racemate; CHEMBL1831075; CHEMBL 1831075; CHEMBL-1831075; BPO-27 racemat. CAS No. 1314873-02-3. Molecular formula: C26H18BrN3O6. Mole weight: 548.34. | |
| BPO-27 racemate | BPO-27 racemate is a potent CFTR inhibitor with an IC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314873-02-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19778A. | |
| BPOPB | BPOPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis(3-(diphenylphosphoryl)phenyl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1863083-31-1. Molecular formula: C42H32O2P2. Mole weight: 630.65 g/mol. Product ID: ACM1863083311. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bpoplive. | |
| BP-OXD-Bpy | BP-OXD-Bpy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6,6'-Bis[5-(biphenyl-4-yl)-1,3,4-oxadiazo-2-yl]-2,2'-bipyridyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1219827-28-7. Molecular formula: C38H24N6O2. Mole weight: 596.64 g/mol. Product ID: ACM1219827287. Alfa Chemistry ISO 9001:2015 Certified. | |
| BPPF | BPPF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9-Bis[4-(pyrenyl)phenyl]-9H-fluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1174006-47-3. Molecular formula: C57H34. Mole weight: 718.88 g/mol. Purity: 95%+. IUPACName: 1-[4-[9-(4-pyren-1-ylphenyl)fluoren-9-yl]phenyl]pyrene. Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2(C4=CC=C(C=C4)C5=C6C=CC7=CC=CC8=C7C6=C(C=C8)C=C5)C9=CC=C(C=C9)C1=C2C=CC3=CC=CC4=C3C2=C(C=C4)C=C1. Product ID: ACM1174006473. Alfa Chemistry ISO 9001:2015 Certified. | |
| BPR1J-097 | BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11?nM. Synonyms: BPR1J097; BPR1J-097; BPR1J 097; BPR1-J097; BPR1 J097; BPR1J097. Grade: >98%. CAS No. 1327167-19-0. Molecular formula: C27H28N6O3S. Mole weight: 516.62. | |
| BPR1J-097 hydrochloride | BPR1J-097 hydrochloride is a potent inhibitor of FLT3 (IC50 = 11 nM) with great anti-tumor activities in vivo. Synonyms: 4-(4-Methyl-1-piperazinyl)-N-(5-{3-[(phenylsulfonyl)amino]phenyl}-1H-pyrazol-3-yl)benzamide hydrochloride (1:1); Benzamide, 4-(4-methyl-1-piperazinyl)-N-[5-[3-[(phenylsulfonyl)amino]phenyl]-1H-pyrazol-3-yl]-, hydrochloride (1:1). Grade: ≥95%. Molecular formula: C27H29ClN6O3S. Mole weight: 553.08. | |
| BPR1J-340 | BPR1J-340 is a potent and selective FLT3 inhibitor with potential anticancer activity. BPR1J-340 was identified as a novel potent FLT3 inhibitor by biochemical kinase activity (IC50 approximately 25 nM) and cellular proliferation (GC50 approximately 5 nM) assays. BPR1J-340 inhibited the phosphorylation of FLT3 and STAT5 and triggered apoptosis in FLT3-ITD(+) AML cells. The pharmacokinetic parameters of BPR1J-340 in rats were determined. BPR1J-340 also demonstrated pronounced tumor growth inhibition and regression in FLT3-ITD(+) AML murine xenograft models. The combination treatment of the HDAC inhibitor vorinostat (SAHA) with BPR1J-340 synergistically induced apoptosis via Mcl-1 down-regulation in MOLM-13 AML cells, indicating that the combination of selective FLT3 kinase inhibitors and HDAC inhibitors could exhibit clinical benefit in AML therapy. Synonyms: BPR1J 340; BPR1J340. Grade: 98%. CAS No. 1395051-72-5. Molecular formula: C29H34N8O3. Mole weight: 542.63. | |
| BPR1K653 | SBPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent activity against the growth of xenograft tumors of the human cervical carcinoma KB and KB-derived MDR1-positive KB-VIN10 cells in nude mice. Finally, BPR1K653 also exhibited favorable pharmacokinetic properties in rats., BPR1K653 is a promising anti-cancer compound that has potential for the management of various malignancies, particularly for patients with MDR1-related drug resistance after prolonged chemotherapeutic treatments. Synonyms: BPR1K653; BPR1K 653; BPR1K-653. Grade: 98%. CAS No. 1192754-07-6. Molecular formula: C30H30Cl2N6O2. Mole weight: 541.04. | |
| BPR1M97 | BPR1M97 is a dual-acting mu-opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist (Kis: 1.8 and 4.2 nM) with blood-brain barrier penetration. It produces potent antinociceptive effects. Synonyms: 3,4-Dichloro-N-[(1,2,3,4-tetrahydro-2-methyl-1-isoquinolinyl)methyl]benzamide. Grade: 98%. CAS No. 2059904-66-2. Molecular formula: C18H18Cl2N2O. Mole weight: 349.25. | |
| BPR1R024 | BPR1R024 is a selective and orally active colony stimulating factor-1 receptor (CSF1R) inhibitor with an IC50 of 0.53 nM. Synonyms: Urea, N-[4-[[7-(dimethylamino)-4-quinazolinyl]oxy]phenyl]-N'-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-. CAS No. 2503015-75-4. Molecular formula: C24H21F3N6O2. Mole weight: 482.46. | |
| BPR1R024 | BPR1R024 is an orally active and selective colony-stimulating factor-1 receptor (CSF1R) inhibitor. BPR1R024 has potent CSF1R inhibition activity with an IC 50 value of 0.53 nM. BPR1R024 can be used for the research of immuno-oncology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2503015-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132935. | |
| BPTAPA | BPTAPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N10,N10'-Bis(4-isopropylphenyl)-N10,N10'-di-p-tolyl-9,9'-bianthracene-10,10'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1848973-32-9. Molecular formula: C60H52N2. Mole weight: 801.07 g/mol. Product ID: ACM1848973329. Alfa Chemistry ISO 9001:2015 Certified. Categories: Betapapillomavirus. | |
| BPTES | BPTES is a potent and selective Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM. Grade: 98%. CAS No. 314045-39-1. Molecular formula: C24H24N6O2S3. Mole weight: 524.68. | |
| BPTES | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BPTES | BPTES is an allosteric and selective glutaminase inhibitor with an IC50 of 0.16 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 314045-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12683. | |
| BPTF-IN-BZ1 | BPTF-IN-BZ1, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 2766623-38-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132889. | |
| BPTF-IN-BZ1 | BPTF-IN-BZ1 is a BPTF inhibitor with high potency (Kd = 6.3 nM). Synonyms: 5-((4-(2-aminoethyl)phenyl)amino)-4-chloro-2-methylpyridazin-3(2H)-one. Molecular formula: C13H15ClN4O. Mole weight: 278.74. | |
| BPTU | BPTU is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM) that binds receptors outside of the helical bundle. BPTU blocks inhibition of spontaneous contraction of rat and mouse colon, which is induced by electrical field activation, nicotine and P2Y agonists. It exhibits antithrombotic activity and reduces platelet aggregation. Uses: Antithrombotic. Synonyms: BPTU; BMS-646786; BMS 646786; BMS646786; BMS compound 16; N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]urea. Grade: ≥98% by HPLC. CAS No. 870544-59-5. Molecular formula: C23H22F3N3O3. Mole weight: 445.43. | |
| Bpu10I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 80% of the dna fragments can be ligated. of these 90% can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 200U; 1000U. CC↑TNAGC GGANT↓CG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer K. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries recombinant plasmids. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 50% glycerol. Cat No: ET-1039RE. | |
| BPU-11 | BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. Synonyms: Biphenyl Urea 11. Grade: >98%. CAS No. 909664-41-1. Molecular formula: C32H31N5O. Mole weight: 501.62. | |
| Bpu14 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. TT↑CGAA AAGC↓TT. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus pumilus 14. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1040RE. | |
| bpV(bipy) | Potent protein phosphotyrosine phosphatase inhibitor Insulin mimetic in vitro and in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1173697-60-3,42494-71-3 (anhydrous). Pack Sizes: 5mg, 25mg. Molecular Formula: K[VO(O2)2C10H8N2] 3H2O. US Biological Life Sciences. | Worldwide |
| bpV(HOpic) | bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumor suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTP β and 25.3 μM for PTP-1 β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury. Group: Biochemicals. Alternative Names: Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V); Bisperoxovanadium (HOpic), Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V). Grades: Highly Purified. CAS No. 722494-26-0. Pack Sizes: 5mg, 25mg. Molecular Formula: K2[VO(O2)2C6H4NO3], Molecular Weight: 347.24. US Biological Life Sciences. | Worldwide |
| bpV(HOpic) | ?90% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| BpV(HOpic) | BpV(HOpic) is a potent and selective inhibitor of PTEN with an IC50 of 14 nM. Nanocarrier-BpV(HOpic) has neuroprotective activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bisperoxovanadium. CAS No. 722494-26-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-128693. | |
| bpV(HOpic) potassium salt | BpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor with IC50 of 14 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 4.9 μM and PTP-1βB with IC50 of 25.3 μM. It is reported to function as an insulin mimetic and activate the insulin receptor kinase (IRK). BpV(HOpic) has been shown to activate the insulin receptor kinase of hepatoma cells and enhance PI3K/Akt signaling, which could prevent ischemia-reperfusion (I/R) injury to the myocardium. Synonyms: Bisperoxovanadium(HOpic). Grade: ≥95%. CAS No. 722494-26-0. Molecular formula: C6H4NO8V·2K. Mole weight: 347.2. | |
| bpV(phen) | Potent protein phosphotyrosine phosphatase inhibitor Insulin receptor kinase (IRK) inducer. Insulin mimetic in vitro and in vivo. Apoptosis inducer. ERK inducer. Mitogen-activated protein kinase phosphatase-1 (MKP-1) inducer. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 171202-16-7. Pack Sizes: 5mg, 25mg. Molecular Formula: K[VO(O2)2C12H8N2]. 3H2O. US Biological Life Sciences. | Worldwide |
| bpV(phen) | ?95% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| bpV(phen) (Potassium bisperoxo (1, 10-phenanthroline) oxovanadate (V)) | A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also an excellent insulin mimetic in vitro and in vivo and a potent PTEN inhibitor (IC50 = 38nM). Group: Biochemicals. Alternative Names: Potassium bisperoxo (1, 10-phenanthroline) oxovanadate (V). Grades: Highly Purified. CAS No. 42494-73-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| bpV(phen) potassium hydrate | BpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 38 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 343 nM and PTP-1β with IC50 of 920 nM. At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase. Synonyms: Bisperoxovanadium(phen); Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Grade: ≥98%. CAS No. 171202-16-7. Molecular formula: C12H8N2O5V·K+(H2O)3. Mole weight: 404.3. | |
| BpV(phen) trihydrate | BpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-? and PTP-1B, respectively. BpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFN?). BpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bisperoxovanadium(phen) trihydrate. CAS No. 171202-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122818. | |
| bpV(pic) | Potent protein phosphotyrosine phosphatase inhibitor. Insulin mimetic. Angiogenesis inhibitor. PTEN inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 148556-27-8. Pack Sizes: 5mg, 25mg. Molecular Formula: K2 [VO(O2)2C6H4NO2] 2H2O. US Biological Life Sciences. | Worldwide |
| bpV(pic) | ?95% V basis. Group: Fluorescence/luminescence spectroscopy. | |
| bpV(pic) (Dipotassium bisperoxo (picolinoto) oxovanadate (V)) | A bisperoxovanadium compound that acts as a potent protein phosphotyrosine phosphatase (PTP) inhibitor as well as an insulin receptor kinase (IRK) activator. Also a potent PTEN inhibitor (IC50= 31nM). Group: Biochemicals. Alternative Names: Dipotassium bisperoxo (picolinoto) oxovanadate (V). Grades: Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| bpV(pic) potassium hydrate | BpV(pic) is composed of a vanadate molecule coordinated to picolinic acid (2-carboxypyridine) and potassium. It is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 31 nM. It is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells and stimulating lipogenesis in adipocytes. BpV(pic) has been shown to activate the insulin receptor kinase (IRK) of cultured hepatoma cells and is also an inhibitor of G6Pase. Synonyms: Bisperoxovanadium(pic). Grade: ≥96%. CAS No. 148556-27-8. Molecular formula: C6H4NO7V·2K·2H2O. Mole weight: 367.3. | |
| Bpy-FOXD | Bpy-FOXD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Bis[2-(2,2'-bipyridine-6-yl)-1,3,4-oxadiazo-5-yl]-9,9-dimethylfluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1174006-45-1. Molecular formula: C39H26N8O2. Mole weight: 638.68 g/mol. Product ID: ACM1174006451. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bpy-OXD | Bpy-OXD. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis[2-(2,2'-bipyridine-6-yl)-1,3,4-oxadiazo-5-yl]benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 866117-19-3. Molecular formula: C30H18N8O2. Mole weight: 522.52 g/mol. Product ID: ACM866117193. Alfa Chemistry ISO 9001:2015 Certified. | |
| BPy-TP2 | Electron transport or hole blocking material in OLEDs. Group: Organic light-emitting diode (oled) materials. Alternative Names: 2, 7-Bis(2, 2'-bipyridin-5-yl)triphenylene, 2, 7-Di(2, 2'-bipyridin-5-yl)triphenylene, -(7-[2, 2'-Bipyridin]-5-yl-2-triphenylenyl)-2, 2'-bipyridine. CAS No. 1394813-58-1. Molecular formula: 536.62. |  |
| BPy-TP2 | sublimed. Group: Oled and pled materials. | |
| BQ-123 | ?99%, sodium salt, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| BQ-123 | BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC 50 of 7.3 nM and a K i of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 136553-81-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12378. | |
| BQ-123 | BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2. Uses: Endothelin receptor antagonists. Synonyms: BQ123; BQ-123; BQ 123. Cyclo(D-trp-D-asp-pro-D-val-leu). Grade: 98%. CAS No. 136553-81-6. Molecular formula: C31H42N6O7. Mole weight: 610.70. | |
| BQ-123 | BQ-123. Group: Biochemicals. Grades: Purified. CAS No. 136553-81-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| BQ-123 Sodium Salt | Potent and selective endothelin receptor A (ETA) antagonist. Suppresses the ET-1-induced decrease of LPL activity. Shows protective effects in ischemic acute renal failure. Neuroprotective. Anti-hypertensive. Inhibits ET-1 receptor binding and blocks Ca2+ mobilization, cellular contraction and MAP kinase activation. Cardiovascular agent. Reduces myocardial infarct size and oxidant injury. Source:Synthetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 136553-81-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H42N6O7 Na. US Biological Life Sciences. | Worldwide |
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