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| Product | Description | |
|---|---|---|
| BH-9PA | BH-9PA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-(10-Phenylanthracen-9-yl)spiro-[benzo[c]fluorene-7,9'-fluorene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1262281-88-8. Molecular formula: C49H30. Mole weight: 618.76 g/mol. Product ID: ACM1262281888. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bhopal disaster. |  |
| BHA | BHA (Butylated Hydroxy Anisole). CAS No. 25013-16-5. FEMA No. 2183. Kosher: Y. VIGON Item # 500563. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| BHA-polystyrene | BHA-polystyrene. Group: Polystyrene (ps). |  |
| BHHT | BHHT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1'-[1,1':2',1''-Terphenyl]-4,4''-diylbis[4,4,5,5,6,6,6-heptafluoro-1,3-hexanedione. Product Category: Other Fluorophores. CAS No. 200862-69-7. Molecular formula: C30H16F14O4. Mole weight: 706.42. Purity: 95%+. IUPACName: 4,4,5,5,6,6,6-heptafluoro-1-[4-[2-[4-(4,4,5,5,6,6,6-heptafluoro-3-oxohexanoyl)phenyl]phenyl]phenyl]hexane-1,3-dione. Canonical SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F)C3=CC=C(C=C3)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F. Density: 1.453 ± 0.06 g/ml. Product ID: ACM200862697-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bharatiya Janata Party. | |
| Bhimamycin A | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin A has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H12O5. Mole weight: 272.25. |  |
| Bhimamycin B | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin B has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Bhimamycin C | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin C has no antibacterial activity. Molecular formula: C17H17NO5. Mole weight: 315.32. | |
| Bhimamycin D | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin D has no antibacterial activity. Molecular formula: C22H15NO6. Mole weight: 389.36. | |
| Bhimamycin E | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/699. Five components A to E are separated. Bhimamycin E selectively inhibits Staphylococcus aureus. Molecular formula: C13H10O5. Mole weight: 246.21. | |
| BHP | BHP is an antibacterial peptide isolated from Bos taurus. | |
| BHPI | BHPI is an antagonist of estrogen receptor α (ERα), for it elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor. Uses: An antagonist of estrogen receptor α (erα). Synonyms: 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one. Grade: ≥95%. CAS No. 56632-39-4. Molecular formula: C21H17NO3. Mole weight: 331.4. | |
| BHQ | BHQ. Group: Biochemicals. Grades: Purified. CAS No. 88-58-4. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| BHQ-1-dT CE Phosphoramidite | BHQ-1-dT, a widely utilized reagent in the biomedicine realm, remains pertinent for nucleic acid detection and DNA sequencing. Its potential significance surfaces in disease and genetic disorder determination alongside viral load monitoring in infectious cases. From a development standpoint, BHQ-1-dT fosters therapeutic targeting of nucleic acids. Synonyms: BHQ-1-dT; HCQ-12-dT Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-1-dT Amidite. Grade: ≥95%. Molecular formula: C74H89N12O14P. Mole weight: 1401.56. | |
| BHQ-2-dT | BHQ-2-dT plays a critical role in propelling PCR probes and hybridization assays to new heights of detection, this modified nucleoside serves as a beacon for identifying viral pathogens, genetic diseases, and cancer biomarkers. With its distinctive fluorescent abilities, molecular matching is taken to the next level of precision and accuracy, boosting sensitivity like never before. Synonyms: HCQ-2-dT Phosphoramidite; BHQ-2-dT CE Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-2-dT Phosphoramidite; BHQ-2-dT Amidite. Grade: ≥95%. CAS No. 1415097-34-5. Molecular formula: C73H87N12O15P. Mole weight: 1403.53. | |
| BHT | BHT (Butylated Hydroxy Toluene). CAS No. 128-37-0. FEMA No. 2184. Kosher: Y. VIGON Item # 500473. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| B-HT 920 | B-HT 920. Group: Biochemicals. Grades: Purified. CAS No. 36085-73-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 920 dihydrochloride | Talipexole is a D2 dopamine receptor agonist, displaying anti-Parkinsonian activity. Uses: A dopamine agonist, also an α2-adrenergic agonist. Synonyms: Talipexole; B-HT 920, B-HT-920, B-HT920, Talipexole HCl, Talipexole dihydrochloride, Domnin6-prop-2-enyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-amine; dihydrochloride; 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride. Grade: ≥98%. CAS No. 36085-73-1. Molecular formula: C10H15N3S; 2HCl. Mole weight: 282.23. | |
| B-HT 920 dihydrochloride talipexole | B-HT 920 dihydrochloride talipexole. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride, 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine dihydrochloride. Grades: Highly Purified. CAS No. 36085-73-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H17Cl2N3S. US Biological Life Sciences. | Worldwide |
| B-HT 920 Dihydrochloride. Talipexole (5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride) | An alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride is a selective α2-adrenoceptor agonist displaying 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor. B-HT 933 decreases blood pressure and cardiac output in cats, and exhibits antinociceptive activity in mice. Uses: Adrenergic alpha-agonists. Synonyms: B-HT 933 dihydrochloride; B-HT933 dihydrochloride; B-HT-933 dihydrochloride; Azepexole hydrochloride; Azepexole dihydrochloride; 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 36067-72-8. Molecular formula: C9H15N3O.2HCl. Mole weight: 254.16. | |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 36067-72-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 958 dihydrochloride | B-HT 958 dihydrochloride is a dopamine D2 receptor agonist and an α2-adrenoceptor partial agonist. Synonyms: B-HT 958 dihydrochloride; B-HT958 dihydrochloride; B-HT-958 dihydrochloride; 4H-Thiazolo(4,5-d)azepin-2-amine, 5,6,7,8-tetrahydro-6-((4-chlorophenyl)methyl)-, dihydrochloride; 2-Amino-6-(4-chlorobenzyl)-4,5,7,8-tetrahydro-6H-thiazolo(5,4-d)azepine dihydrochloride; 5,6,7,8-Tetrahydro-6-((4-chlorophenyl)methyl)-4H-thiazolo(4,5-d)azepin-2-amine dihydrochloride. Grade: 99%. CAS No. 36085-44-6. Molecular formula: C14H16ClN3S.2HCl. Mole weight: 366.74. | |
| BHT-A1 | BHT-A1 is produced by Streptococcus rattus BHT. It is active against Gram-positive bacterials. | |
| BHT-B | BHT-B is produced by Streptococcus rattus BHT. BHT-B is a non-modified 5195Da peptide with some similarity to the tryptophan-rich Staphylococcus aureus bacteriocin, aureocin A53. | |
| b-Hydroxytamoxifen (trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol) | A hydroxylated analogue of tamoxifen with anti-estrogenic properties. Group: Biochemicals. Alternative Names: trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BI-0115 | BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 ?M) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4929-23-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-23999. |  |
| BI01383298 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BI 01383298 | BI01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate co-transporter) with IC50 of 56 nM in HEK cells overexpressing hSLC13A5. BI01383298 is highly selective over other family members and other transporters with >1000-fold selectivity over others. Synonyms: 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide. Grade: ≥98%. CAS No. 2227549-00-8. Molecular formula: C19H19Cl2FN2O3S. Mole weight: 445.34. | |
| BI-0474 | BI-0474 is a potent KRAS G12C inhibitor with IC50 value of 7.0 nM. Synonyms: BI 0474; BI0474. CAS No. 2750570-55-7. Molecular formula: C30H37N9O2S. Mole weight: 587.74. | |
| B I09 | B I09 is a cell permeable IRE-1 RNase inhibitor (IC50 = 1.23 μM) that blocks IRE-1/XBP1 pathway. B I09 exhibits an inhibitory effect on growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model. Uses: Potential treatment of cll. Synonyms: B-I09; B I09; BI09; 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one. Grade: ≥98% by HPLC. CAS No. 1607803-67-7. Molecular formula: C16H17NO5. Mole weight: 303.31. | |
| B I09 | B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1607803-67-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107400. | |
| BI-1347 | BI-1347 is small molecule CDK8 inhibitor with IC50 of 1.1 nM. BI-1347 was shown to enhance NK-cell activity and promote tumor surveillance. Synonyms: BI 1347; BI1347. CAS No. 2163056-91-3. Molecular formula: C22H20N4O. Mole weight: 356.42. | |
| BI-1347 | BI-1347 is an orally active, selective and potent CDK8 inhibitor (IC50=1.1 nM). BI-1347 shows anti-tumoral activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163056-91-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120350. | |
| BI-1408 | BI-1408 is a potent γ-secretase modulator with an IC50 of 0.04 μM for Aβ42. Synonyms: N-[(5R)-1-Ethyl-4,5,6,7-tetrahydro-1H-indazol-5-yl]-8-(4-fluoro-2-methylphenyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine; [1,2,4]Triazolo[1,5-a]pyridin-2-amine, N-[(5R)-1-ethyl-4,5,6,7-tetrahydro-1H-indazol-5-yl]-8-(4-fluoro-2-methylphenyl)-. Grade: ≥90%. CAS No. 2231075-94-6. Molecular formula: C22H23FN6. Mole weight: 390.46. | |
| BI-167107 | BI-167107 is a β-arrestin-biased D2R agonist that binds to β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM. Synonyms: BI 167107; BI167107. Grade: 98%. CAS No. 1202235-68-4. Molecular formula: C21H26N2O4. Mole weight: 370.4. | |
| BI-167107 | BI-167107 is a high affinity, full agonist that binds to the ?2 adrenergic receptor (?2AR) with a dissociation constant Kd of 84 pM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1202235-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121251. | |
| BI-187004 | BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor. BI187004 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs. Synonyms: BI 187004; VTP-34072; VTP 34072; VTP34072; (4AR,9aS)-1-(1H-benzo[d]imidazole-5-carbonyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile. CAS No. 1303515-32-3. Molecular formula: C21H18N4O. Mole weight: 342.40. | |
| BI 224436 | BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of>90 μM. Synonyms: BI-224436; BI 224436; BI224436. Grade: >98%. CAS No. 1155419-89-8. Molecular formula: C27H26N2O4. Mole weight: 442.51. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. | |
| BI-2493 | BI-2493 is a potent pan-KRAS inhibitor that has the potential for the treatment of cancer. Synonyms: BI 2493; BI2493. CAS No. 2937344-16-4. Molecular formula: C24H27N7OS. Mole weight: 461.58. | |
| BI-2493 | BI-2493 is a structural analogue of BI-2865 and a highly selective and orally active pan-KRAS inhibitor. BI-2493 can attenuate tumor growth. BI-2493 can be used for cancer iseases research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2937344-16-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153723. | |
| Bi 2536 | BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively. BI-2536 suppresses IFNB (encoding IFN-β) gene transcription. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI 2536;BI-2536, BoehringerPLK-1 inhibitor;4-[[(7R)-8-Cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide;Benzamide,4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-;Boehringer PLK-1 inhibitor;BI-2536(R-);BI2536/BI-2536;(R)-4-((8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-Methoxy-N-(1-Methylpiperidin-4-yl)benzaMide. Product Category: Inhibitors. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.662. Purity: 0.9979. Density: 1.28. Product ID: ACM755038029. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI 2536 | BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively[1]. BI-2536 suppresses IFNB (encoding IFN-?) gene transcription[4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 755038-02-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50698. | |
| BI-2536 | BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division. Synonyms: BI2536; BI 2536; (R)-4-((8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide. Grade: 98%. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.65. | |
| BI-2545 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BI-2545 | BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC 50 s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2162961-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124772. | |
| BI-2852 | BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based agent design with nanomolar affinity. BI-2852 is mechanistically distinct from covalent KRASG12C inhibitor (binds to switch II pocket) and binds ten-fold more strongly to active KRASG12D versus KRASwt (740 nM vs 7.5 ?M). BI-2852 blocks GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2375482-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126247. | |
| BI-2852 | BI-2852 is a KRAS inhibitor. It blocks the interaction of GEF, GAP and effectors with KRAS, thereby inhibiting downstream signal transduction and producing anti-proliferative effects in KRAS mutant cells. Synonyms: BI-2852; 2375482-51-0; CHEMBL4750445; (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one; (3S)-5-hydroxy-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1H-indol-3-yl]-2,3-dihydroisoindol-1-one; F0K; SCHEMBL24414712; BCP31539; EX-A4793; BDBM50549225; s8959; AKOS040732592; BI2852; BI 2852; MS-29593; HY-126247; CS-0100975; A934943; (S)-5-Hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one; (S)-5-hydroxy-3-(2-(((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methylamino)methyl)-1H-indol-3-yl)isoindolin-1-one. Grade: ≥98% by HPLC. CAS No. 2375482-51-0. Molecular formula: C31H28N6O2. Mole weight: 516.6. | |
| BI-2865 | BI-2865 is a none-covalent pan-KRAS Inhibitor. It inhibits tumor growth in mice bearing KRAS G12C, G12D, G12V. Synonyms: BI 2865; BI2865. CAS No. 2937327-93-8. Molecular formula: C23H27N7O2S. Mole weight: 465.57. | |
| BI-2865 | BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2937327-93-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153724. | |
| Bi2Te3 Crystal | Bi2Te3 Crystal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bismuthsesquitelluride;bismuthtelluride(bi2te3);bismuthtelluride,undoped;bismuthtritelluride;tellurobismuthite;tellururedebismuth;BISMUTH TELLURIDE;BISMUTH (III) TELLURIDE. Product Category: Graphene-like Materials Series. CAS No. 1304-82-1. Molecular formula: Bi2Te3. Mole weight: 800.76. Purity: 0.99995. Product ID: ACM1304821. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3406 | BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230836-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-125817. | |
| BI-3406 | BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Synonyms: BI 3406; BI3406. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.5. | |
| BI-3406 | BI-3406 is Potent & Selective SOS1:KRAS Inhibitor (IC50=5 nM), which Opens a New Approach for Treating KRAS-Driven Tumours. BI 3406 selectively binds to SOS1 and blocks the interaction with KRAS, irrespective of the KRAS mutation. BI 3406 causes RAS GTP and pERK reduction and inhibits cell growth of KRAS mutated cell lines, carrying most of the typical KRAS mutations (i.e. G12D, G12V, G13D and others). BI 3406, when administered orally to tumour bearing mice, causes a dose dependent tumour static effect that can be converted into regressions when combined with MEK1 inhibition. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI-3406; BI 3406; BI3406. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.47. Purity: >98%. IUPACName: N-((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-7-methoxy-2-methyl-6-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Canonical SMILES: C[C@H](C1=CC(N)=CC(C(F)(F)F)=C1)NC2=C3C(C=C(OC)C(O[C@H]4CCOC4)=C3)=NC(C)=N2. Product ID: ACM2230836550. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3802 | BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ?3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2166387-65-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108705. | |
| BI-3802 | BI-3802 is a highly potent BCL6 degrader that inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. It induces BCL6 polymerization and degradation via E3 ligase SIAH1, showing antitumor activity. Grade: ≥98% by HPLC. CAS No. 2166387-65-9. Molecular formula: C24H29ClN6O3. Mole weight: 484.98. | |
| BI-3812 | BI-3812 is potent and efficacious BCL6 inhibitor. It inhibits the BTB domain of BCL6 with an IC50 of ≤3 nM. The high potency and good permeability properties of BI-3812 make this molecule a very good cellular probe compound for testing hypotheses around BCL6 biology. The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Synonyms: BI-3812; 2166387-64-8; CHEMBL4755229; 1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide; SCHEMBL20284237; AMY16876; BCP31903; EX-A2841; BDBM50546197; s8735; AKOS040741329; SB40386; BI 3812; BI3812; AC-31571; MS-30157; HY-111381; CS-0040299; A935150; EN300-22885148; Z3417458909; 1-[5-chloro-4-({8-methoxy-1-methyl-3-[(methylcarbamoyl)methoxy]-2-oxo-1,2-dihydroquinolin-6-yl}amino)pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide; 1-[5-Chloro-4-({8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1,2-dihydro-6-quinolinyl}amino)-2-pyrimidinyl]-N,N-dimethyl-4-piperidinecarboxamide; 1-[5-chloro-4-[[8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxoquinolin-6-yl]amino]pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide. Grade: ≥98%. CAS No. 2166387-64-8. Molecular formula: C26H32ClN7O5. Mole weight: 558.03. | |
| BI-4020 | BI-4020 is an orally active EGFR inhibitor. Synonyms: BI 4020; BI4020. CAS No. 2573869-33-5. Molecular formula: C30H38N8O2. Mole weight: 542.68. | |
| BI-409306 | BI-409306 is a potent and selective inhibitor of phosphodiesterase 9A (PDE9A). BI-409306 has been researched as a candidate for the treatment of schizophrenia. Uses: Phosphodiesterase inhibitors. Synonyms: BI 409306; BI409306; SUB 166499; Osoresnontrine. CAS No. 1189767-28-9. Molecular formula: C16H17N5O2. Mole weight: 311.34. | |
| BI-4394 | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor ( IC 50=1 nM [1] ) for the potential treatment of osteoarthritis [2]. BI-4394 is >1000 selective over other MMPs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MMP13-IN-3. CAS No. 1222173-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124029. | |
| BI-4464 | BI-4464 is a highly selective, ATP competitive PTK2/FAK protein kinase inhibitor with an IC50 value of 17 nM. BI-4464 can be used as a PTK2 ligand for constructing proteolysis targeting chimeras (PROTAC). Uses: Scientific research. Group: Signaling pathways. CAS No. 1227948-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124625. | |
| BI-44847 | BI-44847 is a synthetic bio-active chemical had been in phase II clinical trials for the treatment of type 2 diabetes. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: BI-44847; BI 44847; BI44847; UNII-43WJ33399D; beta-D-Glucopyranoside,4-((2-fluoro-4-methoxyphenyl)methyl)- 5-methyl-1-(1-methylethyl)-1H-pyrazol-3-yl. Grade: ≥98%. CAS No. 421592-30-5. Molecular formula: C21H29FN2O7. Mole weight: 440.46. | |
| BI-4834 | BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. Synonyms: BI4834; BI 4834. Grade: >98%. CAS No. 876371-13-0. Molecular formula: C21H42N4O3S3. Mole weight: 593.76. | |
| BI-4916 | BI-4916 is a proagent of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor. BI-4916 inhibits cancer cell migration. BI-4916 can be used for cancer, inflammation and infection study[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244451-48-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126253. | |
| BI 6015 | BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of tumor cell lines, including human hepatocellular carcinoma. Synonyms: BI6015; BI 6015; BI-6015. 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole. Grade: ≥98% by HPLC. CAS No. 93987-29-2. Molecular formula: C15H13N3O4S. Mole weight: 331.35. | |
| BI 6015 | BI 6015. Group: Biochemicals. Grades: Purified. CAS No. 93987-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BI-6015 | BI-6015 is a hepatocyte nuclear factor 4? (HNF4?) antagonist that can inhibit the expression of known HNF4? target genes. BI6015 represses insulin promoter activity through HNF4? antagonism. BI-6015 can be used for the research of cancer and diabetes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93987-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108469. | |
| BI605906 | BI605906 is a novel pharmacological inhibitors of the IKK family. It inhibits IKKβ with an IC50 value of 380 nM when assayed at 0.1 mM ATP in vitro. It also inhibits TNFα-dependent IκB degradation and expression of pro-inflammatory mediators IL-6, IL-1b, and CXCL1/2. It not only prevents the phosphorylation of physiological substrates, but also prevents the phosphorylation of the serine residues in IKKβ that trigger its activation. Uses: Bi605906 not only prevents the phosphorylation of physiological substrates, but also prevents the phosphorylation of the serine residues in ikkβ that trigger its activation. Synonyms: BI605906; BI-605906; BI 605906; 3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide. Grade: >98 %. CAS No. 960293-88-3. Molecular formula: C17H22F2N4O3S2. Mole weight: 432.51. | |
| BI 639667 | BI 639667 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC 50 of 1.8 nM in Ca 2+ flux assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR1 antagonist 8. CAS No. 1295298-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-120588. | |
| BI671800 | BI671800 is a CRTH2 antagonist. It is used to treat patients with asthma. It is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on inhaled corticosteroid (ICS) therapy. Uses: Bi671800 is used to treat patients with asthma. Synonyms: AP-761; AP 761; AP761; 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]-; 2-(4,6-Bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl)acetic acid; BI-671800; BI 671800; BI671800. Grade: >98%. CAS No. 1093108-50-9. Molecular formula: C25H26F3N5O3. Mole weight: 501.51. | |
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