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| Product | Description | |
|---|---|---|
| Bexotegrast | Bexotegrast (PLN-74809) is an orally active, potent dual αvβ6/αvβ1 integrin inhibitor with K d of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits αvβ6- and αvβ1-induced TGF-β activation with IC 50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-β activation in the fibrotic lung [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLN-74809. CAS No. 2376257-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137561. |  |
| Beyerol | It is produced by the strain of Beyeria (euphorbiaceae) leschenaultii (DC) Bail. Synonyms: (+)-Beyerol; (+)-15-beyerene-3alpha,17,19-triol; NSC83440; ((3R,4R,4aS,6aR,9R,11aS,11bS)-3-hydroxy-4,11b-dimethyl-2,3,4,4a,5,6,10,11,11a,11b-decahydro-6a,9-methanocyclohepta[a]naphthalene-4,9(1H)-diyl)dimethanol; (4R,8R,13R)-13-(Hydroxymethyl)-17-norkaur-15-ene-3α,18-diol; 17-Norkaur-15-ene-3,18-diol, 13-(hydroxymethyl)-, (3α,4α,8β,13β)-. CAS No. 6040-48-8. Molecular formula: C20H32O3. Mole weight: 320.47. |  |
| Beyerol 17-cinnamate | It is produced by the strain of Beyeria (euphorbiaceae) leschenaultii var. drummondii. Synonyms: 17-Norkaur-15-ene-3,18-diol, 13-[[(1-oxo-3-phenyl-2-propen-1-yl)oxy]methyl]-, (3alpha,4alpha,8beta,13beta)-; 17-Norkaur-15-ene-3,18-diol, 13-[[(1-oxo-3-phenyl-2-propen-1-yl)oxy]methyl]-, (3α,4α,8β,13β)-; beyerol 17-monocinnamate; (8β,13R)-13-Cinnamoyloxymethyl-17-norkaur-15-ene-3β,18-diol; ((3R,4R,4aS,6aR,9R,11aS,11bS)-3-hydroxy-4-(hydroxymethyl)-4,11b-dimethyl-2,3,4,4a,5,6,10,11,11a,11b-decahydro-6a,9-methanocyclohepta[a]naphthalen-9(1H)-yl)methyl cinnamate. CAS No. 59219-79-3. Molecular formula: C29H38O4. Mole weight: 450.61. | |
| Beyerol, dihydro-, triacetate | Beyerol, dihydro-, triacetate. CAS No. 105403-79-0. Molecular formula: C26H40O6. Mole weight: 448.59. | |
| Beyerol triacetate | Beyerol triacetate. CAS No. 102216-95-5. Molecular formula: C26H38O6. Mole weight: 446.58. | |
| Beyeryl tribenzoate | Beyeryl tribenzoate. CAS No. 106068-02-4. Molecular formula: C41H44O6. Mole weight: 632.78. | |
| BEZ235 Tosylate | BEZ235 tosylate is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Synonyms: NVP-BEZ235; BEZ 235 Tosylate; BEZ-235 Tosylate. Grade: >98%. CAS No. 1028385-32-1. Molecular formula: C37H31N5O4S. Mole weight: 641.74. | |
| Bezafibrate | analytical standard. Group: Additional drugspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Befizal,Bezafibrate, 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid, Bezatol, Bezalip, Difaterol, Cedur, Benzofibrate, BM 15075. |  |
| Bezafibrate | Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used for the treatment of hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. Uses: Hypolipidemic agents. Synonyms: BM 15075; BM15075; BM-15075. Grade: >98%. CAS No. 41859-67-0. Molecular formula: C19H20ClNO4. Mole weight: 361.82. | |
| Bezafibrate | Bezafibrate is an agonist of PPAR , with EC 50 s of 50 μM, 60 μM, 20 μM for human PPARα , PPARγ and PPARδ , and 90 μM, 55 μM, 110 μM for murine PPARα , PPARγ and PPARδ , respectively; Bezafibrate is used as an hypolipidemic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM15075. CAS No. 41859-67-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0637. | |
| Bezafibrate | Bezafibrate. Group: Biochemicals. Alternative Names: 2-[4-[2-[ (4-Chlorobenzoyl) amino]ethyl]phenoxyl]-2-methylpropanoic acid; BM-15075; Befizal. Grades: Highly Purified. CAS No. 41859-67-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C19H20ClNO4. US Biological Life Sciences. |  Worldwide |
| Bezafibrate (2-[4-[2-[ (4-Chlorobenzoyl) amino]ethyl]phenoxyl]-2-methylpropanoic Acid,. BM-15075, Befizal, Bezalip, Bezatol, Cedur, Difaterol) | Antilipemic. Group: Biochemicals. Alternative Names: 2-[4-[2-[ (4-Chlorobenzoyl) amino]ethyl]phenoxyl]-2-methylpropanoic Acid;BM-15075; Befizal; Bezalip; Bezatol; Cedur; Difaterol. Grades: Highly Purified. CAS No. 41859-67-0. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| Bezafibrate Acyl Glucuronide | Bezafibrate Acyl Glucuronide is an impurity of Bezafibrate. Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used for the treatment of hyperlipidaemia. Synonyms: Bezafibrate 1-O-beta-Glucuronide; Benzabate monocelloacyl glucuronide. CAS No. 72156-77-5. Molecular formula: C25H28ClNO10. Mole weight: 537.95. | |
| Bezafibrate-[d4] | Bezafibrate-[d4] is the labelled analogue of Bezafibrate. Bezafibrate is a fibrate drug used for the treatment of hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. Synonyms: Bezafibrate-d4; 2-{4-[2-(4-Chlorobenzamido-d4)ethyl]phenozy}-2-methylpropanoic Acid; BM-15075-d4; Befizal-d4; Bezalip-d4; Bezatol-d4; Cedur-d4; Difaterol-d4. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 1189452-53-6. Molecular formula: C19H16D4ClNO4. Mole weight: 365.85. | |
| Bezafibrate-[d6] | Bezafibrate-[d6] is the labelled analogue of Bezafibrate. Bezafibrate is a fibrate drug used for the treatment of hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. Synonyms: Bezafibrate D6; Bezafibrate-d6 (dimethyl-d6); 2-{4-[2-(4-Chlorobenzamido)ethyl]phenozy}-2-methylpropanoic Acid-d6; BM-15075-d6; Befizal-d6; Bezalip-d6; Bezatol-d6; Cedur-d6; Difaterol-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1219802-74-0. Molecular formula: C19H14D6ClNO4. Mole weight: 367.86. | |
| Bezafibrate Impurity D | Bezafibrate Impurity D is a derivative of Bezafibrate. Synonyms: Bezafibrate Ethyl Ester; 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic Acid Ethyl Ester; Ethyl 2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate. Grade: > 95%. CAS No. 41859-58-9. Molecular formula: C21H24ClNO4. Mole weight: 389.88. | |
| Bezisterim | Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis [1] [2] [3]. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HE 3286; NE-3107. CAS No. 1001100-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108039. | |
| Bezlotoxumab | Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1246264-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9929. | |
| Bezuclastinib | Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557. | |
| Bezuclastinib | Bezuclastinib, a tyrosine kinase inhibitor, is a potent c-kit and c-kit D816V inhibitor (0.0001| | |
| BF-168 | BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki = 6.4 nM for A1-42). Synonyms: BF 168; 6-(2-fluoroethoxy)-2-(2-(4-methylaminophenil)ethenyl)benzoxazole. Grade: 99%. CAS No. 634911-47-0. Molecular formula: C18H17FN2O2. Mole weight: 312.34. | |
| BF-170 hydrochloride | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| BF2 | BF2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,6-Bis((E)-4-(diphenylamino)styryl)-5-(ethoxycarbonyl)-2,2-difluoro-2H-1,3,2-dioxaborinin-1-ium-2-uide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2243376-97-6. Molecular formula: C46H37BF2N2O4. Mole weight: 730.6 g/mol. Product ID: ACM2243376976. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BF 227 | BF 227 is a candidate used for diagnostic imaging of diseases with amyloid β protein accumulation. Synonyms: BF-227; BF227; 2-[2-(2-dimethylaminothiazol-5-yl-)ethenyl]-6-[2-fluoroethoxy]benzoxazole. CAS No. 845647-80-5. Molecular formula: C16H16FN3O2S. Mole weight: 333.38. | |
| BF 2649 | Pitolisant hydrochloride is an antagonist of the histamine H3 receptor, which is used for the treatment of narcolepsy with or without cataplexy in adult patients. Uses: The treatment of narcolepsy with or without cataplexy. Synonyms: BF 2649; BF2649; BF-2649; pitolisant hydrochloride; Wakix; 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine hydrochloride. CAS No. 903576-44-3. Molecular formula: C17H27Cl2NO. Mole weight: 332.309. | |
| BF 2649 hydrochloride | BF 2649 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 903576-44-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BF738735 | BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIII?) inhibitor with an IC50 of 5.7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1436383-95-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-U00426. | |
| BF738735 | A potent and selective ATP-competitive phosphatidylinositol 4-kinase III beta (PI 4-KIIIβ) inhibitor (IC50 = 5.7 nM). Displays approximately 200-fold selectivity over PI 4-KIIIα. Broad spectrum enterovirus replication inhibitor. Synonyms: 1436383-95-7; BF738735; 2-fluoro-4-(2-methyl-8-((3-(methylsulfonyl)benzyl)amino)imidazo[1,2-a]pyrazin-3-yl)phenol; CHEMBL2407818; 2-fluoro-4-[2-methyl-8-[(3-methylsulfonylphenyl)methylamino]imidazo[1,2-a]pyrazin-3-yl]phenol; BF 738735; C21H19FN4O3S; GLXC-25537; BDBM50492527; HY-U00426; MFCD31619316; AKOS040742416; DA-61637; SY125659; WS-01993; CS-0035356; W15611; 2-Fluoro-4-[2-methyl-8-[[3-(methylsulfonyl)benzyl]amino]-3-imidazo[1,2-a]pyrazinyl]phenol; 2-fluoro-4-(8-{[(3-methanesulfonylphenyl)methyl]amino}-2-methylimidazo[1,2-a]pyrazin-3-yl)phenol. Grade: ≥98%. CAS No. 1436383-95-7. Molecular formula: C31H57N5O9. Mole weight: 643.8. | |
| BF844 | BF844 is a CLRN1N48K stabilizer that can attenuate progressive hearing loss and deafness in an Usher syndrome type III (USH3) mouse model. Uses: Hearing loss therapy. Synonyms: BioFocus 844; BioFocus844; BioFocus-844; BF844; BF-844; BF 844; 4-Chloro-α,α-dimethyl-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine-1-ethanol. Grade: 98%. CAS No. 1404506-35-9. Molecular formula: C21H19ClN4O. Mole weight: 378.85. | |
| B-factor | B-factor is extracted from yeast. Synonyms: 3'-(1-Butylphosphoryl)adenosine; 3'-Adenylic acid, monobutyl ester. CAS No. 52278-63-4. Molecular formula: C14H22N5O7P. Mole weight: 403.33. | |
| BFB | BFB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-dioctylfluorenyl-2,7-diyl)-alt-(N,N'-bis{4-butylphenyl}-benzidine-N,N'-{1,4-diphenylene})]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 223569-32-2. Molecular formula: (C73H82N2)n. Product ID: ACM223569322. Alfa Chemistry ISO 9001:2015 Certified. | |
| BFCAs-1 | BFCAs-1 is a polyamino polycarboxylic bifunctional chelating agent, which has a broad range of applications in chemistry, biology and medicine and diagnostic imaging. Grade: >98%. CAS No. 585531-74-4. Molecular formula: C32H60N4O8. Mole weight: 628.84. | |
| BF-CATH | Cathelicidin-BF is a short antimicrobial peptide, which was originally extracted from the venom of Bungarus fasciatus. Recent studies have reported that Cath-BF and some related derivatives exert strong antimicrobial and weak hemolytic properties. Synonyms: Cath-BF. | |
| BF-DPB | BF-DPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4'-Bis(9,9-dimethyl-9H-fluoren-2-yl)-N4,N4'-diphenylbiphenyl-4,4'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 361486-60-4. Molecular formula: C54H44N2. Mole weight: 720.94 g/mol. Purity: 95%+. IUPACName: N-[4-[4-(N-(9,9-dimethylfluoren-2-yl)anilino)phenyl]phenyl]-9,9-dimethyl-N-phenylfluoren-2-amine. Canonical SMILES: CC1(C2=CC=CC=C2C3=C1C=C(C=C3)N(C4=CC=CC=C4)C5=CC=C(C=C5)C6=CC=C(C=C6)N(C7=CC=CC=C7)C8=CC9=C(C=C8)C1=CC=CC=C1C9(C)C)C. Density: 1.178 ± 0.06 g/ml. Product ID: ACM361486604. Alfa Chemistry ISO 9001:2015 Certified. | |
| BFF 122 | BFF 122 is a potent and selective inhibitor of kynurenine aminotransferase II (IC50 = 1 μM and >30 μM for KAT II and KAT I respectively). Synonyms: BFF122; BFF 122; BFF-122; BF5; (S)-9-(4-Amino-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid. Grade: 99%. CAS No. 1152314-49-2. Molecular formula: C17H19FN4O4. Mole weight: 362.36. | |
| bFGF (119-126) | bFGF (119-126) is a biological active peptide. (This peptide corresponds to human, bovine (119-126), mouse, rat (118-125) and Heparin-Binding Growth Factor 2 (118-125) residues of bFGF. It inhibits dimerization and activation of bFGF receptors.). Uses: Scientific research. Group: Peptides. CAS No. 152051-61-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5321. | |
| BFH772 | BFH772 is a potent oral VEGFR2 inhibitor, which is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890128-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100419. | |
| BFH772 | BFH772, a structure analogue of BAW2881, was highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM, however, lost 500-fold potency on FLK-1, FLT-1, and FLT-4. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM. Synonyms: 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide; BFH-772; BFH 772; BFH772; 1-Naphthalenecarboxamide, 6-((6-(hydroxymethyl)-4-pyrimidinyl)oxy)-N-(3-(trifluoromethyl)phenyl)-. CAS No. 890128-81-1. Molecular formula: C23H16F3N3O3. Mole weight: 439.4. | |
| b-Fluoro-DL-alanine | b-Fluoro-DL-alanine. Group: Biochemicals. Grades: Highly Purified. CAS No. 43163-93-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C3H6FNO2. US Biological Life Sciences. | Worldwide |
| b-Fluoro-DL-alanine ≥97% (GC) | b-Fluoro-DL-alanine ≥97% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences. | Worldwide |
| BG45 | BG45 is a class I HDAC inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3, HDAC1, HDAC2, and HDAC6 in cell-free assays, respectively. Synonyms: BG45; BG-45; BG 45. Grade: 98%. CAS No. 926259-99-6. Molecular formula: C11H10N4O. Mole weight: 214.22. | |
| BG45 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| b-Galactosyl 1-3 N-acetyl galactosamine methyl glycoside | b-Galactosyl 1-3 N-acetyl galactosamine methyl glycoside is a sophisticated compound, functioning as an artfully engineered synthetic glycoside. Thereby, it orchestrates nuanced manipulation of cellular processes instrumental in compound administration, focused therapeutics, or malady identification. Synonyms: Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside; β-Galactosyl 1-3 N-acetyl galactosamine methyl glycoside; N-Acetyl-3-O-beta-D-galactopyranosyl-beta-D-galactosamine methyl glycoside; N-Acetyl-3-O-β-D-galactopyranosyl-β-D-GA. Grade: ≥98%. CAS No. 88274-25-3. Molecular formula: C15H27NO11. Mole weight: 397.38. | |
| b-Galactosylceramides from bovine brain | b-Galactosylceramides from bovine brain, derived from the ample tissues of bovine brain, stand as naturally occurring glycosphingolipids. Their intrinsic attributes have unveiled a realm of possibilities in biomedical research, particularly delving into the intricate realm of immune responses and tumor development. Synonyms: Ceramide b-D-galactosides; Cerebrosides. CAS No. 85305-88-0. Molecular formula: C48H93NO9. Mole weight: 828.3. | |
| BGB-283 | BGB-283 is a selective Epidermal growth factor receptor and Proto oncogene protein b raf inhibitor under the development of BeiGene. BGB-283 shows antitumor activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 can inhibit B-RAFV600E-activated ERK phosphorylation and cell proliferation. In vivo, BGB-283 can lead to dose-dependent tumor growth inhibition accompanied by partial and complete tumor regressions in both cell-line derived and primary human colorectal tumor xenografts bearing B-RAFV600E mutation. Phase I clinical trials for the treatment of solid tumours are on-going. Uses: Solid tumours. Synonyms: UNII-8762XZS5ZF; 8762XZS5ZF; BGB-283; BGB 283; BGB283; Beigene-283; Beigene283; Beigene 283; Lifirafenib; Compound 2.2b; Beigene-283; GTPL8958; 5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one. Grade: 98%. CAS No. 1446090-77-2. Molecular formula: C25H17F3N4O3. Mole weight: 478.31. | |
| BGC-20-1531 | BGC-20-1531 is a high-affinity and selective EP4 antagonist (Ki = 3 nM). BGC-20-1531 has the potential for the treatment of migraine headache. Synonyms: BGC 20-1531; BGC201531; BGC-201531; BGC 201531; GTPL3380; GTPL-3380; GTPL 3380; AP-1531; AP1531; AP1531. Grade: >98%. CAS No. 1186532-61-5. Molecular formula: C26H23N2NaO6S. Mole weight: 514.53. | |
| BGC-20-1531 free base | BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP 4 receptor antagonist, with a pK B of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGN 1531 free base. CAS No. 736183-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19849. | |
| BGC-20-1531 free base | BGC-20-1531 is a selective EP4 receptor antagonist with a pKB of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache. Synonyms: BGC-201531; PGN 1531 free base; 4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide. Grade: 98%. CAS No. 736183-35-0. Molecular formula: C26H24N2O6S. Mole weight: 492.54. | |
| BGC 20-1531 hydrochloride | BGC 20-1531 hydrochloride is a potent and selective EP4 antagonist, which exhibits <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors. It has high affinity and selective with Ki of 3 nM for EP4 antagonist. BGC 20-1531 antagonizes PGE2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA. It also reverses PGE2-induced vasorelaxation with Kb of 15.85 nM in human middle cerebral and middle meningeal arterial rings. Synonyms: BGC20-1531 HCl; BGC20-1531 hydrochloride; BGC20-1531; BGC 20-1531; BGC-20-1531; BGC201531; BGC 201531; BGC-201531; PGN 1531; PGN-1531; PGN1531. Grade: ≥98%. CAS No. 1962928-26-2. Molecular formula: C26H24N2O6S·HCl. Mole weight: 529. | |
| BGC 20-761 | BGC 20-761 is a selective, high affinity 5-HT6 antagonist (Ki = 20 nM). BGC 20-761 was shown to reverse the amnesic effects of scopolamine and enhance memory consolidation in a rat model. Synonyms: BGC-20-761; BGC 20 761; 5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine; N,N-Dimethyl-2-(5-methoxy-2-phenylindol-3-yl)ethylamine. Grade: ≥98% by HPLC. CAS No. 17375-63-2. Molecular formula: C19H22N2O. Mole weight: 294.39. | |
| BGC 20-761 | BGC 20-761. Group: Biochemicals. Grades: Purified. CAS No. 17375-63-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BGC-638 | BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. Synonyms: BGC 638; BGC638; CB300638; CB-300638; D-Glutamic acid, N-(4-(2-propyn-1-yl((6S)-4,6,7,8-tetrahydro-2-methyl-4-oxo-3H-cyclopenta(g)quinazolin-6-yl)amino)benzoyl)-L-gamma-glutamyl-. CAS No. 416852-27-2. Molecular formula: C32H33N5O9. Mole weight: 631.64. | |
| BGC-945 | BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R)-2-((S)-4-carboxy-4-(4-(((S)-2-(hydroxymethyl)-4-oxo-4,6,7,8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl)(prop-2-yn-1-yl)amino)benzamido)butanamido)pentanedioic acid. Grade: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63. | |
| b-Gentiobiose octaacetate | b-Gentiobiose octaacetate is a biomedical compound employed extensively in drug development and research, predominantly recognized as a safeguarding tool for delicate pharmaceuticals. This compound remarkably aids drug delivery and augments stability. Moreover, its application extends to the investigation of ailments such as cancer, diabetes and neurodegenerative disorders, thereby effectively unraveling their intricate mechanisms and potential researchs. Synonyms: 1,2,3,4-Tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-glucopyranose; β-D-Glucopyranose, 6-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-, 1,2,3,4-tetraacetate; Gentiobiose octaacetate; β-D-Glucopyranose, 6-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-, tetraacetate; β-Gentiobiose octaacetate. CAS No. 4613-78-9. Molecular formula: C28H38O19. Mole weight: 678.59. | |
| BGJ-398 | BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea; NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib. Grade: 0.98. CAS No. 872511-34-7. Molecular formula: C26H31Cl2N7O3. Mole weight: 560.48. | |
| Bgl I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. GCCNNNN↑NGGC CGGN↓NNNNCCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer 2W. Storage: -20°C. Form: Liquid. Source: Bacillus globigii. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1033RE. |  |
| Bgl II | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. A↑GATCT TCTAG↓A. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Bgl II gene from Bacillus globigii. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1034RE. | |
| b-Glucosylglycerol 2,3,4,6-tetraacetate | b-Glucosylglycerol 2,3,4,6-tetraacetate, a remarkable compound, exhibits immense potential as an antidiabetic agent. In the realm of diabetes management, this prodigious specimen reigns, adeptly regulating blood glucose levels and fostering insulin sensitivity enhancement. Beyond its primary scope, it gracefully unveils itself as a viable therapeutic alternative for diverse metabolic afflictions. Synonyms: 2-(Tetraacetylglucosido)glycerol; 2-Hydroxy-1-(hydroxymethyl)ethyl b-D-glucopyranoside 2,3,4,6-tetraacetate; 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl glycerol; Glycerol, 2-(tetraacetylglucosido)-; β-D-Glucopyranoside, 2-hydroxy-1-(hydroxymethyl)ethyl, 2,3,4,6-tetraacetate. CAS No. 157024-67-4. Molecular formula: C17H26O12. Mole weight: 422.38. | |
| b-Glucuronidase Inhibitor (1-((6,8-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-3-(4-ethoxyphenyl)-1-(2-hydroxyethyl)thiourea) | An orally bioavailable trisubstituted thiourea compound that acts as a potent, uncompetitive and reversible inhibitor of bacterial b-glucuronidase activity (IC50 = 283nM; kcat/Km=0.0987s-1uM-1; Ki4nM in vitro assays against E. coli b-glucuronidase; EC50.7nM in b-glucuronidase expressing HB101 cells) with excellent selectivity over mammalian b-glucuronidases. Shown to directly target the 17-residue (360-376) loop structure that protects the active site of E. coli b-glucuronidase and alter its conformation. Displays negligible cytotoxicity toward both bacterial and mammalian epithelial cells (>100uM for HCT116, Caco-2 and CMT93 colon cancer cells) and offers protection against CPT-11 (50mg/kg, i.p., s.i.d. for 9 days)-induced toxicity in mice (10ug, p.o., b.i.d). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| b-Glutamic acid hydrochloride 98+% (TLC) | b-Glutamic acid hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 336182-10-6. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Glycerophosphate Disodium Salt Hydrate 99+% | Used as an organic phosphate donor and to buffer cell culture media. Group: Biochemicals. Alternative Names: Glycerol 2-phosphate disodium salt hydrate. Grades: Reagent Grade. CAS No. 154804-51-0. Pack Sizes: 5g, 25g, 100g, 250g. Molecular Formula: C3H7Na2O6P; xH2O, Molecular Weight: 234. US Biological Life Sciences. | Worldwide |
| b-Glycerophosphoric acid disodium salt pentahydrate | b-Glycerophosphoric acid disodium salt pentahydrate. Group: Biochemicals. Alternative Names: Disodium b-glycerophosphate pentahydrate; Glycerol 2-phosphate disodium salt pentahydrate. Grades: Highly Purified. CAS No. 819-83-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C3H7O6P·2Na·5H2O. US Biological Life Sciences. | Worldwide |
| BGP-15 | BGP-15 is a PARP inhibitor, with an IC50 and a Ki of 120 and 57 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 66611-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100828. | |
| BGP-15 | BGP-15 is a PARP inhibitor, with an IC50 and a Ki of 120 and 57 μM, respectively. Uses: Enzyme inhibitors. Synonyms: BGP15; BGP 15; 3-Pyridinecarboximidamide, N-(2-hydroxy-3-(1-piperidinyl)propoxy)-, hydrochloride (1:2). Grade: >98%. CAS No. 66611-37-8. Molecular formula: C20H40N4O3S3. Mole weight: 351.27. | |
| BGP-15 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BGT226 | BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability. Synonyms: BGT-226; BGT 226; BGT-226 free base; BGT226 free base; NVP-BGT226; 1,3-Dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2H-imidazo[4,5-c]quinolin-2-one. Grade: 98%. CAS No. 915020-55-2. Molecular formula: C32H29F3N6O6. Mole weight: 534.54. | |
| BGT226 maleate | BGT226 (NVP-BGT226 maleate) is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3K?, PI3K? and PI3K?) /mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-BGT226 maleate. CAS No. 1245537-68-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13334. | |
| Bh3i-1 | BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.316. Purity: ≥98.0%. Product ID: ACM300817689. Alfa Chemistry ISO 9001:2015 Certified. Categories: BH3 interacting-domain death agonist. | |
| BH3I-1 | BH3I-1 is a cell-permeable inhibitor that targets Bcl-2 family protein. It inhibits the binding of BH3 peptides to Bcl-xL and induces apoptosis of Bcl-xL expressing cells. Synonyms: BH3I-1; BH 3I-1; BH-3I-1; BH3I1; BH 3I1; BH-3I1. 2-[(5E)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic acid. Grade: 99%. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.31. | |
| BH3I-1 | ?97% (HPLC), powder, yellow. Group: Fluorescence/luminescence spectroscopy. | |
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