A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
BI 894999 is a potent and selective BET inhibitor. BI 894999 targets super-enhancer-regulated oncogenes and other lineage-specific factors, which are involved in the maintenance of the disease state. Synonyms: BI-894999; BI894999; BRD4 Inhibitor-10. CAS No. 1660117-38-3. Molecular formula: C25H27N5O2. Mole weight: 429.51.
BI 9321
BI 9321 is a nuclear receptor-binding SET domain (NSD) 3 antagonist with IC50 of 1.2 μM. It is also selectively binds the PWWP1 domain of NSD3 with Kd of 166 nM. BI 9321 antagonizes the interaction of H3 with NSD3-PWWP1 in U2OS cells. High selectivity of BI-9321 was confirmed using in vitro assays and quantitative chemical proteomics. Cellular target engagement was confirmed with FRAP (Fluorescence Recovery After Photobleaching) and BRET (Bioluminescence Resonance Energy Transfer) at 1 μM. Synonyms: (4-(5-(7-Fluoroquinolin-4-yl)-1-methyl-1H-imidazol-4-yl)-3,5-dimethylphenyl)methanamine trihydrochloride. Grade: ≥98%. Molecular formula: C22H21FN4ยท3HCl. Mole weight: 469.81.
BI-9321
BI-9321 is a potent, selective and cellular active antagonist of nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain with a Kd of 166 nM. BI-9321 has no activity against NSD2-PWWP1 and NSD3-PWWP2, and specifically disrupts histone interactions in the NSD3-PWWP1 domain, with an IC50 of 1.2 μM in U2OS cells. Synonyms: 1-{4-[5-(7-Fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethylphenyl}methanamine; Benzenemethanamine, 4-[5-(7-fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethyl-. Grade: ≥95%. CAS No. 2387510-86-1. Molecular formula: C22H21FN4. Mole weight: 360.43.
BI-9321 trihydrochloride
BI-9321 trihydrochloride is a potent, selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist with a Kd value of 166 nM. BI-9321 trihydrochloride is inactive against NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts histone interactions of the NSD3-PWWP1 domain with an IC50 of 1.2 ?M in U2OS cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387510-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114208A.
BI-9564
BI-9564 is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14.1 and 239 nM; IC50s = 75 nM and 3.4 μM, respectively), with selectivity for BRD9/7 over 48 other bromodomains, 324 kinases and 55 GPCRs. Synonyms: 4-(4-((dimethylamino)methyl)-2,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one; BI-9564; BI 9564; BI9564. CAS No. 1883429-22-8. Molecular formula: C20H23N3O3. Mole weight: 353.42.
BI-9564 is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 ?M and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 ?M for BET family[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883429-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100352.
BI-9627
BI-9627 is a potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor (IC50 = 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays). BI-9627 displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. BI-9627 decreases autophagy in HTR-8/SVneo cells. BI-9627 can significantly reduce the pHi of human sperm and partially reverse the effect of DMA. BI-9627 prolongs Ca2+ recovery time in KO hiPSC-CMs. BI-9627 shows low DDI (agent-agent interaction) potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injury[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204329-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18071.
BI-9627 hydrochloride
Sodium-hydrogen exchanger isoform 1 (NHE1) is a ubiquitously expressed transmembrane ion channel. BI-9627 hydrochloride is sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor. Synonyms: BIX HCl. Grade: 98%. CAS No. 1422252-46-7. Molecular formula: C16H20ClF3N4O2. Mole weight: 392.8.
BI 99179
BI 99179 is a potent and selective inhibitor of type I fatty acid synthase (FAS) with IC50 of 79 nM. Synonyms: BI-99179; BI99179; (1R,3S)-N-(4-(Benzo[d]oxazol-2-yl)phenyl)-N-methyl-3-propionamidocyclopentanecarboxamide. Grade: 99%. CAS No. 1291779-76-4. Molecular formula: C23H25N3O3. Mole weight: 391.46.
BI 99179
BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1291779-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16100.
BI 99990
BI 99990 is a negative control compound of the active enantiomer BI 99179. Synonyms: BI-99990; BI99990; (1S,3R)-N-(4-(Benzo[d]oxazol-2-yl)phenyl)-N-methyl-3-propionamidocyclopentanecarboxamide. Grade: 98%. CAS No. 1338468-86-2. Molecular formula: C23H25N3O3. Mole weight: 391.46.
BIA
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2. Synonyms: TMBIM6 antagonist BIA; (E)-1-(2-Aminophenyl)-3-(3-nitrophenyl)prop-2-en-1-one. Grade: 99%. CAS No. 134271-74-2. Molecular formula: C15H12N2O3. Mole weight: 268.27.
BIA 10-2474
BIA 10-2474 is an inhibitor of fatty acid amide hydrolase ( FAAH ) with IC 50 values of 50 to 70mg/kg in various rat brain regions. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233855-46-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19740.
BIA10-2474
This active molecular is a reversible FAAH (fatty acid amide hydrolase) inhibitor that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (except the brain and spinal cord) under the development of Bial-Portela & Ca. SA. BIA 10-2474 can interact with the human endocannabinoid system and was inpplicated in the treatment of a range of different medical conditions including anxiety, Parkinson's disease, chronic pain of multiple sclerosis, cancer, hypertension and obesity. Clinical trial with BIA 10-2474 was on-going. However, severe adverse events occurred in January 2016 affecting 5 patients, including leading to the death of one. Uses: Neurological disorders; pain; psychiatric disorders. Synonyms: BIA 10-2474; BIA-10-2474; BIA10-2474; N-cyclohexyl-N-methyl-4-(1-oxidopyridin-1-ium-3-yl)imidazole-1-carboxamide; UNII-5AP1ZW859M; SCHEMBL427970; 5AP1ZW859M; GTPL9001; DOWVMJFBDGWVML-UHFFFAOYSA-N. Grade: 98%. CAS No. 1233855-46-3. Molecular formula: C16H20N4O2. Mole weight: 300.36.
Biacangelicol (Byakangelicol). Group: Biochemicals. Alternative Names: Biacangelicol. Grades: Plant Grade. CAS No. 26091-79-2. Pack Sizes: 20mg. Molecular Formula: C17H16O6, Molecular Weight: 316.305. US Biological Life Sciences.
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Biadamantylidene
Biadamantylidene. Group: Biochemicals. Grades: Highly Purified. CAS No. 30541-56-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C20H28. US Biological Life Sciences.
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Biafungin acetate
Biafungin acetate is a next-generation, broad-spectrum, and long-lasting echinocandin. It shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp. Synonyms: Rezafungin acetate; CD101 acetate; CD-101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Molecular formula: C65H88N8O19. Mole weight: 1285.44.
Bialamicol hydrochloride
Bialomicol is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: Bialamicol Hydrochloride; Bialamicol hydrochloride [USAN]; CAM 807; CAM-807; Camoform hydrochloride; CI 301; CI301; CI-301; NSC 6386; PAA 701 dihydrochloride; PAA-701; PAA701 dihydrochloride; SN 6771 dihydrochloride; UNII-VIQ3X36S8C; 2-(diethylaminomethyl)-4-[3-(diethylaminomethyl)-4-hydroxy-5-prop-2-enylphenyl]-6-prop-2-enylphenol; dihydrochloride. Grade: ≥98%. CAS No. 3624-96-2. Molecular formula: C28H42Cl2N2O2. Mole weight: 509.556.
Bialaphos
10mg Pack Size. Group: Biochemicals, Building Blocks, Organics, Peptide Reagents, Research Organics & Inorganics. Formula: C11H22N3O6P. CAS No. 35597-43-4. Prepack ID 14973551-10mg. Molecular Weight 323.28. See USA prepack pricing.
Bialaphos
Bialaphos is a phosphorus-containing tripeptide produced by Streptomyces viridochromogenes and Str. hygroscopicus. It has anti-bacterial, anti-fungal activity, and has herbicidal effect. Synonyms: Bilanafos; Herby; Antibiotic SF 1293. Grade: >98%. CAS No. 35597-43-4. Molecular formula: C11H22N3O6P. Mole weight: 323.28.
Bialaphos sodium
A freely soluble herbicide synthesized by streptomyces hygroscopicus and streptomyces viridochromeogenes. CAS No. 71048-99-2. Molecular formula: C11H21N3NaO6P. Mole weight: 345.27.
Bialaphos sodium
Bialaphos (SF-1293) sodium, an antibiotic , is an effective herbicide is a metabolite of Streptomyces hygroscopicus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SF-1293 sodium. CAS No. 71048-99-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122494A.
Bialaphos Sodium Salt
Bialaphos Sodium Salt is a tripeptide antibiotic that is employed in the transformation experiments of many species of plants that make use of the bar gene for selection. It is more effective than glufosinate in corn. In wheat, bialaphos was the most reliable selection criteria used to identify bar transformed plants. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (hydroxy methyl phosphinyl) butanoyl-L-alanyl-L-alanine Monosodium Salt; γ - (Hydroxy methyl phosphinyl) -L- α -aminobutyryl-L-alanyl-L-alanine Monosodium Salt; Bilanafos Sodium Salt; Herbi-Ace; Herbie; MW 801; SF 1293. Grades: Highly Purified. CAS No. 71048-99-2. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C??H??N?NaO?P, Molecular Weight: 345.26. US Biological Life Sciences.
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Bianntennary N-linked core pentasaccharide
Bianntennary N-linked core pentasaccharide is a pivotal compound assuming a momentous function in the examination of glycosylation motifs and their inherent physiological mechanisms. Through its utilization, one may delve into the intricate biosynthetic pathways and alterations conversant with N-linked glycans. Synonyms: GlcNAcβ1-2Manα1-6Man3-1Manα2-1βGlcNAc. Grade: ≥95%. Molecular formula: C34H58N2O26. Mole weight: 910.82.
Bianthronyl
Bianthronyl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (9,9'-Bianthracene)-10,10'(9H,9'H)-dione;9,10-Dianthrone;BIANTHRONYL;10,10'-DIHYDROBIANTHRONE;10,10'-DIHYDRODIANTHRONE;Anthrone dimer;10-(10-keto-9H-anthracen-9-yl)-10H-anthracen-9-one;10-(10-oxo-9H-anthracen-9-yl)-10H-anthracen-9-one. Product Category: Heterocyclic Organic Compound. CAS No. 434-84-4. Molecular formula: C28H18O2. Mole weight: 386.44. Purity: 0.96. IUPACName: 10-(10-oxo-9H-anthracen-9-yl)-10H-anthracen-9-one. Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C3C2=O)C4C5=CC=CC=C5C(=O)C6=CC=CC=C46. Density: 1.293g/cmยณ. Product ID: ACM434844. Alfa Chemistry ย ISO 9001:2015 Certified.
Biapenem
Biapenem is a carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents respectively. It has a role as an antibacterial drug. It is a member of carbapenems, a pyrazolotriazole and an organic sulfide. Alternative Names: Omegacin. Biapenern. L-627. CAS No. 120410-24-4. Product ID: API120410244. Molecular formula: C15H18N4O4S. Mole weight: 350.4. SMILES: CC1C2C(C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])C(C)O. Appearance: Off-white to pale yellow solid. Category: Antibiotic APIs.
Biapenem
An carbapenem antibacterial. Group: Biochemicals. Alternative Names: 6-[[(4R,5S,6S)-2-Carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium Inner Salt; Biapenern; Omegacin. Grades: Highly Purified. CAS No. 120410-24-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Biapenem
Biapenem is a carbapenem antibiotic with in vitro activity against anaerobes. Synonyms: Omegacin; Biapenern; L-627; L 627; L627. Grade: 98%. CAS No. 120410-24-4. Molecular formula: C15H18N4O4S. Mole weight: 350.39282.
Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CLI 86815; L 627; LJC 10627. CAS No. 120410-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13573.
Biapigenin
It is isolated from the herbs of Hypericum perforatum L. Synonyms: [3,8'-Bi-4H-1-benzopyran]-4,4'-dione, 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-; 5,5',7,7'-Tetrahydroxy-2,2'-bis(4-hydroxyphenyl)[3,8'-bi-4H-1-benzopyran]-4,4'-dione; 3,8''-Biapigenin; 8,3''-Biapigenin; I3,II8-Biapigenin. Grade: 98%. CAS No. 101140-06-1. Molecular formula: C30H18O10. Mole weight: 538.46.
BIBB 515
2,3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. It is concluded that the lipid-lowering effect of BIBB 515 is mainly the result of an inhibition of LDL production rather than due to an increase in LDL catabolism. OSC inhibitors may offer a novel approach for lipid-lowering therapy. Synonyms: BIBB-515; BIBB515. Grade: ≥98%. CAS No. 156635-05-1. Molecular formula: C22H21ClN2O2. Mole weight: 380.9.
Bibenzyl
1,2-Diphenylethane is a kind of widely used aromatic hydrocarbon compound. Synonyms: 2-phenylethylbenzene. CAS No. 103-29-7. Molecular formula: C14H14. Mole weight: 182.26.
BIBF0775
BIBF0775 is an inhibitor of transforming growth factor beta receptor I (TGFβRI) with an IC50 of 34 nM. Synonyms: (Z)-N-Ethyl-N-Methyl-2-Oxo-3-(Phenyl((4-(Piperidin-1-Ylmethyl)Phenyl)Amino)Methylene)Indoline-6-Carboxamide. Grade: ≥98% by HPLC. CAS No. 334951-90-5. Molecular formula: C31H34N4O2. Mole weight: 494.6.
BIBN 4096
BIBN 4096. Group: Biochemicals. Grades: Purified. CAS No. 204697-65-4. Pack Sizes: 10mg. US Biological Life Sciences.
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BIBO 3304 trifluoroacetate
BIBO 3304 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 191868-14-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BIBO 3304 trifluoroacetate
BIBO 3304 trifluoroacetate is a potent NPY Y1 receptor antagonist (IC50 = 0.38 and 0.72 nM at human and rat receptors, respectively) displaying > 2600-fold selectivity over Y2, Y4 and Y5 receptors. BIBO 3304 inhibits NPY- and fasting-induced feeding in vivo following central administration. It may be a treatment of bone mass. Synonyms: BIIE-0246; BIIE 0246; BIIE-0246; CHEMBL540989; GTPL1547; CTK8E9439; BIIE0246; N-[(1R)-1-[[[[4-[[(Aminocarbonyl)amino]methyl]phenyl]methyl]amino]carbonyl]-4-[(aminoiminomethyl)amino]butyl]-α-phenyl-benzeneacetamide ditrifluoroacetate. Grade: ≥98% by HPLC. CAS No. 191868-14-1. Molecular formula: C29H35N7O3.2CF3CO2H. Mole weight: 757.69.
BIBP 3226 is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, >1000, >1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). It exhibits an anxiogenic-like effect in rats following i.c.v. administration. Synonyms: BIBP3226; BIBP-3226; N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine amide; (R)-2-Diphenylacetylamino-5-guanidino-pentanoic acid 4-hydroxy-benzylamide; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide; N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide; Diphenylacetyl-D-Arg-4-hydroxybenzylamide. Grade: ≥98%. CAS No. 159013-54-4. Molecular formula: C27H31N5O3. Mole weight: 473.57.
BIBP 3226 TFA
BIBP 3226 trifluoroacetate is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). BIBP 3226 exhibits an anxiogenic-like effect in rats following i.c.v. administration. Synonyms: BIBP 3226 trifluoroacetate; BIBP3226 trifluoroacetate; BIBP-3226 trifluoroacetate; N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide trifluoroacetate; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide trifluoroacetate; Diphenylacetyl-D-Arg-4-hydroxybenzylamide trifluoroacetate. Grade: ≥98% by HPLC. CAS No. 1068148-47-9. Molecular formula: C27H31N5O3.C2HF3O2. Mole weight: 587.59.
BIBP3226 TFA
BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with K i s of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1068148-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107726.
BIBP 3226 trifluoroacetate
BIBP 3226 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 1068148-47-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
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BIBR 1532
BIBR 1532. Group: Biochemicals. Grades: Purified. CAS No. 321674-73-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BIBR 1532
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM.BIBR1132 is highly selective for inhibition of telomerase, resulting in delayed growth arrest of tumor cells. Treatment of cancer cells with BIBR1532 leads to progressive telomere shortening, consecutive telomere dysfunction, and finally growth arrest after a lag period that is largely dependent on initial telomere length. Synonyms: BIBR1532; BIBR-1532; BIBR 1532. Grade: >98%. CAS No. 321674-73-1. Molecular formula: C21H17NO3. Mole weight: 331.36.
BIBR 1532
BIBR 1532 is a potent, selective and non-competitive telomerase inhibitor with IC 50 of 100 nM in a cell-free assay. Uses: Scientific research. Group: Signaling pathways. CAS No. 321674-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17353.
BIBS 39
BIBS 39, a nonpeptide angiotensin II receptor antagonist, has been found to exhibit potential antihypertensive activity in rat. It has been already discontinued against hypertension. Uses: Bibs 3 is a nonpeptide angiotensin ii receptor antagonist that has been found to exhibit potential antihypertensive activity in rat. Synonyms: BIBS-39; BIBS39; BIBS 39.; CHEMBL130896; 2-[4-[[2-butyl-6-(cyclohexylcarbamoylamino)benzimidazol-1-yl]methyl]phenyl]benzoic acid; AC1L2ZGG. Grade: 98%. CAS No. 133085-33-3. Molecular formula: C32H36N4O3. Mole weight: 524.65.
BIBS 39
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 133085-33-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19732.
BIBU 1361 dihydrochloride
BIBU 1361 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 793726-84-8. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
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BIBU 1361 dihydrochloride
BIBU 1361 dihydrochloride is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM) with ~ 100-fold lower potency than ErbB2 (IC50 = 290 nM) and selectivity over a range of other related tyrosine kinases (IC50 > 10 μM). BIBU 1361 blocks downstream EGFR signaling events such as MAPKK/MAPK activation. Synonyms: BIBU 1361 dihydrochloride; BIBU1361 dihydrochloride; BIBU-1361 dihydrochloride; N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-amine dihydrochloride. Grade: ≥97% by HPLC. CAS No. 793726-84-8. Molecular formula: C22H27ClFN7.2HCl. Mole weight: 516.87.
BIBX 1382 dihydrochloride
BIBX 1382 dihydrochloride is a potent and selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM) with > 1000-fold lower potency than ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). BIBX 1382 inhibits Lassa, Ebola and Marburg viruses. Synonyms: BIBX 1382 dihydrochloride; BIBX1382 dihydrochloride; BIBX-1382 dihydrochloride; Falnidamol Dihydrochloride; N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)-pyrimido[5,4-d]pyrimidine-2,8-diamine dihydrochloride. Grade: ≥97% by HPLC. CAS No. 1216920-18-1. Molecular formula: C18H19ClFN7.2HCl. Mole weight: 460.77.
BIBX 1382 dihydrochloride
BIBX 1382 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216920-18-1. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
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Bicalutamide
Bicalutamide is a non-steroidal androgen receptor (AR) antagonist with IC50 of 0.16 μM. Synonyms: ICI 176334; ICI-176334; ICI176334; Abbreviation: CDX. US brand name: Casodex. Foreign brand name: Cosudex. Grade: >98%. CAS No. 90357-06-5. Molecular formula: C18H14F4N2O4S. Mole weight: 430.37.
Bicalutamide
Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal); Non-steroidal androgen receptor antagonist that binds the androgen receptor and prevents its activation. Group: Biochemicals. Alternative Names: N-[4-Cyano-3-trifluoromethyl) phenyl]-3-[ (4-fluorophenyl) sulfonyl]-2-hydroxy-2-methylpropanamide; ICI-176334; Casodex; Cosudex; ICI 176334; ZD 176334. Grades: Highly Purified. CAS No. 90357-06-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg. Molecular Formula: C18H14F4N2O4S, Molecular Weight: 430.37. US Biological Life Sciences.
Worldwide
Bicalutamide
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: ZD 176334, (+/-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide, Bicalutamide, Casodex, Cosudex,N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide, (+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide, ICI 176334.
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H14F4N2O4S. CAS No. 90357-06-5. Prepack ID 88023166-1g. Molecular Weight 430.37. See USA prepack pricing.
Bicalutamide
Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90357-06-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-14249.
Bicalutamide-[d4] is the labelled analogue of Bicalutamide. Bicalutamide is a non-steroidal androgen receptor (AR) antagonist with IC50 of 0.16 μM. It is commonly used for the treatment of prostate cancer. Synonyms: Bicalutamide D4; N-[4-Cyano-3-trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4; ICI-176334-d4; Casodex-d4. Grade: ≥97% by HPLC; ≥98% atom D. CAS No. 1185035-71-5. Molecular formula: C18H10D4F4N2O4S. Mole weight: 434.41.
Used as an antiandrogen, antineoplastic (hormonal). Group: Biochemicals. Alternative Names: ICI-176334-d4; Casodex-d4; N-[4-Cyano-3-trifluoromethyl) phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bicalutamide EP Impurity E
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity E; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(RS)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38.
Bicalutamide EP Impurity F
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity F; (2SR)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(RS)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C18H14F4N2O3S. Mole weight: 414.38.
Bicalutamide EP Impurity H
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity H; (2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-[(4-fluorophenyl)sulfonyl]-3-hydroxy-2-methylpropanamide; N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-[(4-fluorophenyl)sulfonyl]-3-hydroxy-2-methylpropanamide. Grade: ≥95%. CAS No. 2512198-58-0. Molecular formula: C18H14F4N2O4S. Mole weight: 430.37.
Bicalutamide EP Impurity K
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity K; (2R,2'S)-3,3'-Sulfonylbis[N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide]; (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(((R)-3-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-hydroxy-2-methyl-3-oxopropyl)sulfonyl)-2-hydroxy-2-methylpropanamide. Grade: ≥95%. Molecular formula: C24H20F6N4O6S. Mole weight: 606.49.
Bicalutamide EP Impurity L
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity L; (2RS,2'RS)-3,3'-Sulfonylbis[N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide]; 3,3'-Sulfonylbis(N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide). Grade: ≥95%. CAS No. 2711603-77-7. Molecular formula: C24H20F6N4O6S. Mole weight: 606.49.
Bicalutamide EP Impurity M
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity M; (2RS)-3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic acid; 3-[(4-Fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoic acid; (+/-)-3-((4-Fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanoic acid. Grade: >95%. CAS No. 151262-57-6. Molecular formula: C10H11FO5S. Mole weight: 262.26.
Bicalutamide EP Impurity M
Bicalutamide EP Impurity M. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methylpropanoic acid. CAS No. 151262-57-6. Molecular formula: C10H11FO5S. Mole weight: 262.26. Catalog: APB151262576.