A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cerdulatinib, also known as PRT2070 and PRT062070, is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types. IL2 mediated STAT5 Y694 was inhibited with an IC50 of 0.27uM, while IL4 mediated signaling to STAT6 Y641 and functional responses in B cells and monocytes, namely CD69, CD25, and CD23 up-regulation, were inhibited with IC50 within the range of 0.11uM to 0.57uM. It is currently being studied in patients with genetically-defined hematologic cancers, as well as for patients who have failed therapy due to relapse or acquired mutations. Synonyms: Cerdulatinib; PRT2070; PRT-2070; PRT 2070; PRT-062070; PRT 062070; PRT062070. CAS No. 1198300-79-6. Molecular formula: C20H27N7O3S. Mole weight: 445.542.
Cerdulatinib HCl
Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Synonyms: Cerdulatinib hydrochloride; PRT2070 hydrochloride; 4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide hydrochloride. Grade: >98%. CAS No. 1369761-01-2. Molecular formula: C20H28ClN7O3S. Mole weight: 482.
Cerebellin
Cerebellin is a neuromodulatory peptide widely distributed in the central nervous system. Synonyms: Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His; Cerebellin (rat); L-seryl-glycyl-L-seryl-L-alanyl-L-lysyl-L-valyl-L-alanyl-L-phenylalanyl-L-seryl-L-alanyl-L-isoleucyl-L-arginyl-L-seryl-L-threonyl-L-asparagyl-L-histidine. Grade: ≥95% by HPLC. CAS No. 94071-26-8. Molecular formula: C69H113N23O23. Mole weight: 1632.78.
Cerebroside A
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Molecular formula: C41H75NO9. Mole weight: 726.03.
Cerebroside b
Cerebroside b. Alternative Names: 1-O-Pivaloyl-glycerin; Propanoic acid,2,2-dimethyl-,2,3-dihydroxypropyl ester; glucocerebroside; 1-pivaloyloxypropane-2,3-diol. CAS No. 88642-46-0. Purity: 97%. Product ID: ACM88642460. Molecular formula: C41H77NO9. Mole weight: 728.07. IUPAC Name: (2R)-2-hydroxy-N-[(2S,3R,4E,8E)-3-hydroxy-9-methyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadeca-4,8-dien-2-yl]hexadecanamide. Canonical SMILES: CCCCCCCCCCCCCCC(C(=O)NC(COC1C(C(C(C(O1)CO)O)O)O)C(C=CCCC=C(C)CCCCCCCCC)O)O. Alfa Chemistry - ISO 9001:32057 Certified.
Cerebroside B
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Synonyms: 1-O-beta-d-glucopyranosyl-(2s,3r,4e,8e)-2-[(2r)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol; 1-O-Pivaloyl-glycerin; 1-pivaloyloxypropane-2,3-diol; Propanoic acid,2,2-dimethyl-,2,3-dihydroxypropyl ester; glucocerebroside. Grade: >97%. CAS No. 88642-46-0. Molecular formula: C41H77NO9. Mole weight: 728.05.
Cerebroside B
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88642-46-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3570.
Cerebroside C
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Synonyms: Cerebroside PO 9; (2R,3E)-N-[(1S,2R,3E,7E)-1-[(β-D-Glucopyranosyloxy)methyl]-2-hydroxy-8-methyl-3,7-heptadecadienyl]-2-hydroxy-3-octadecenamide; [1S-[1R*(2S*,3E),2S*,3E,7E]]-N-[1-[(β-D-Glucopyranosyloxy)methyl]-2-hydroxy-8-methyl-3,7-heptadecadienyl]-2-hydroxy-3-octadecenamide; (2S,2'R,3R,3'E,4E,8E)-1-O-D-Glucopyranosyl-2-N-(2'-hydroxy-3'-octadecenoyl)-3-hydroxy-9-methyl-4,8-sphingadienine. CAS No. 98677-33-9. Molecular formula: C43H79NO9. Mole weight: 754.09.
Cerebroside D
It is produced by the strain of Pachybasium sp. It has strong anti-candida albicans B311 activity in the presence of aculeacin with 0.05 ?/mL. Cerebroside D is a glycoceramide compound with antitumor activity. Study on murine experimental colitis showed that cerebroside D reduced weight loss and the macroscopic as well as microscopic appearances of colitis induced by dexran sulfate sodium. Cerebroside D also inhibited proliferation and induced apoptosis of T cells activated by concanavalin A or anti-CD3 plus anti-CD28 antibodies. Synonyms: (2S,2'R,3R,4E,8E)-N-2'-hydroxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-9-methyl-4,8-sphingadienine; (R)-2-Hydroxy-octadecanoic acid [(3E,7E)-(1S,2R)-2-hydroxy-8-methyl-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-heptadeca-3,7-dienyl]-amide. Grade: 96.5%. CAS No. 113773-89-0. Molecular formula: C43H81NO9. Mole weight: 756.117.
Cerebrosides (Brain)
Cerebrosides are glycosphingolipids with either glucose or galactose as a polar head group. Cerebrosides are amphipathic in nature. They comprise the major component of the myelin lipids. Cerebrosides are part of non-neural cells including the epithelial cells associated with skin and the digestive system. Synonyms: Total Cerebrosides (Brain, Porcine). Grade: >99%. CAS No. 383906-25-0. Molecular formula: C48H93NO8. Mole weight: Average: 781.953.
cerebroside-sulfatase
Hydrolyses galactose-3-sulfate residues in a number of lipids. Also hydrolyses ascorbate 2-sulfate and many phenol sulfates. Group: Enzymes. Synonyms: arylsulfatase A; cerebroside sulfate sulfatase. Enzyme Commission Number: EC 3.1.6.8. CAS No. 9068-68-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3758; cerebroside-sulfatase; EC 3.1.6.8; 9068-68-2; arylsulfatase A; cerebroside sulfate sulfatase. Cat No: EXWM-3758.
Cerebroside sulfate
Cerebroside sulfate is a remarkable biomedical compound, exhibiting prodigious potential for studying diverse neurological disorders such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. Its distinctive configuration and inherent characteristics render it an alluring contender for novel drug development aiming at the central nervous system. Encouraging outcomes from preclinical investigations substantiate its capacity to transform the research landscape of these incapacitating illnesses. Synonyms: Sulfatides; Ceramide-galactoside-3-sulfate; 3-O-sulfo-b-D-C24-galactosylceramide. CAS No. 85496-63-5. Molecular formula: C42H80NNaO11S. Mole weight: 830.14.
Cereolysin
Cerebrolysin is a multimodal neuropeptide drug used for the treatment of ischemic and hemorrhagic stroke, brain trauma, dementia and cognitive impairment. It can improve the brain's self-repair ability by stimulating nerve recovery. Synonyms: HE383245. CAS No. 72270-31-6. Molecular formula: C59H94N16O19S. Mole weight: 1363.54.
Ceresin
Ceresin is a white-to-yellow waxy mixture of hydrocarbons obtained by purification of ozokerite. It occurs as odorless, tasteless, amorphous (noncrystalline) brittle, waxy cakes or pastilles. Synonyms: Cera mineralis alba; ceresine; ceresine wax; ceresin wax; cerin; cerosin; Cirashine CS; earth wax; GS-Ceresin; Koster Keunen Ceresine; mineral wax; purified ozokerite; Ross Ceresine Wax; white ceresin wax; white ozokerite wax. CAS No. 8001-75-0. Product ID: PE-0605. Category: Coating Agents; Opacifier; Stabilizing Agents; Stiffening Agents. Product Keywords: Other Materials; Stabilizers; PE-0605; Ceresin; Coating Agents; Opacifier; Stabilizing Agents; Stiffening Agents; ; 8001-75-0. UNII: Q1LS2UJO3A. Grade: Pharmceutical Excipients. Administration route: Topical. Dosage Form: Topical ointments; vaginal emulsions and cream. Stability and Storage Conditions: Ceresin should be stored in well-closed containers in a cool, dry, well-ventilated place, away from extreme heat and strong oxidizing agents. Source and Preparation: Ceresin is prepared by extraction and purification of the native mineral fossil wax ozokerite, which is derived from coal and shale.Ozokerite is mined from deposits in various localities around the world. It is found as irregular mineral veins or as a black mass in clay strata. Mined ozokerite is heated to melt it, and any earth or rock is removed. If necessary, it is heated to 115-120°C to remove any moisture
Ceresin
Ceresin.
Cerestat
Cerestat, a naphthalenyl-guanidine derivative, which has been found to be a potent and noncompetitive NMDA receptor antagonist(IC50 = 36 nM) and exhibits more than 70-fold selectivity for NMDA receptor over σ receptor. Synonyms: N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride; CNS 1102. Grade: ≥98% by HPLC. CAS No. 137160-11-3. Molecular formula: C20H21N3.HCl. Mole weight: 339.86.
Cereulide
Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K+, and transports K+ from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation, inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy. Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 157232-64-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P3003.
Cereulide-13C6
Cereulide-13C6 is a deuterated form of Cereulide. Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K+, and transports K+ from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation, inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy. Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning. Uses: Scientific research. Category: Signaling pathways. CAS No. 1487375-69-8. Pack Sizes: 20 μg (17.25 μM * 1 mL in Acetonitrile). Product ID: HY-P3003S.
cerevisin
From Saccharomyces cerevisiae (baker's yeast, brewer's yeast). In peptidase family S8 (subtilisin family), but contains a Cys residue near the active site His, and is inhibited by mercurials. Proteinase ycaB is a similar enzyme from the yeast Candida albicans. Group: Enzymes. Synonyms: yeast proteinase B; proteinase yscB; baker's yeast proteinase B; brewer's yeast proteinase; peptidase &beta. Enzyme Commission Number: EC 3.4.21.48. CAS No. 37288-81-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4141; cerevisin; EC 3.4.21.48; 37288-81-6; yeast proteinase B; proteinase yscB; baker's yeast proteinase B; brewer's yeast proteinase; peptidase &beta. Cat No: EXWM-4141.
Cerevisterol
Cerevisterol is a steroid isolated from the fruiting bodies of Agaricus blazei[1]. Uses: Scientific research. Category: Natural products. CAS No. 516-37-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3571.
Cerexin A
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. Synonyms: Antibiotic 60-6; CEREXIN-A; LS-52766. CAS No. 55467-31-7. Molecular formula: C63H103N15O19. Mole weight: 1374.58.
Cerexin B
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 55467-34-0. Molecular formula: C69H107N15O17. Mole weight: 1418.67.
Cerexin B1
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-81-6. Molecular formula: C66H99N15O18. Mole weight: 1390.58.
Cerexin B4
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-84-9. Molecular formula: C66H101N15O18. Mole weight: 1392.59.
Cerexin D4
It is produced by the strain of Bac.cereus Gp-3. It has anti-gram-positive bacterial activity. CAS No. 70943-88-3. Molecular formula: C66H101N15O17. Mole weight: 1376.60.
Cergutuzumab amunaleukin
Cergutuzumab amunaleukin (CEA-IL2v) is a monomeric carcinoembryonic antigen (CEA)-targeted IL-2 variant-based immunocytokine. Cergutuzumab amunaleukin has immunostimulating and antineoplastic activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CEA-IL2v; RG 7813; RO 6895882. CAS No. 1509916-03-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99498.
Ceric ammonium nitrate
Ceric ammonium nitrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 16774-21-3. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: Ce(NH4)2·(NO3)6. US Biological Life Sciences.
Worldwide
Ceric Ammonium Nitrate
Ceric Ammonium Nitrate. CAS No. 16774-21-3. Molecular formula: H8N8CeO18.
Ceric ammonium sulfate dihydrate ≥94% ACS
Ceric ammonium sulfate dihydrate ≥94% ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 10378-47-9. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
Worldwide
Ceric (IV) Sulfate Tetrahydrate
Ceric (IV) Sulfate Tetrahydrate. CAS No. 10294-42-5. Molecular Formula Ce(SO4)2 * 4H2O. Chemical Reagents
Cater Chemicals Corp. Illinois IL
Ceric nitrate
Ceric nitrate. CAS No. 13093-17-9. Product ID: ACM13093179. Molecular formula: CeH2N6O18. Mole weight: 388.14. Alfa Chemistry - ISO 9001:32057 Certified.
Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib shows great antitumor potency[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LDK378. CAS No. 1032900-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-15656.
Ceritinib
An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Synonyms: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. Grade: ≥98%. CAS No. 1032900-25-6. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14.
Ceritinib
Ceritinib. Group: Biochemicals. Alternative Names: LDK 378. Grades: Highly Purified. CAS No. 1032900-25-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H36CIN5O3S. US Biological Life Sciences.
Worldwide
Ceritinib dihydrochloride
Ceritinib (LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride shows great antitumor potency[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LDK378 dihydrochloride. CAS No. 1380575-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15656A.
Ceritinib Impurity 1
Ceritinib Impurity 1. Uses: For analytical and research use. Alternative Names: 1-chloro-5-isopropoxy-2-methyl-3-nitrobenzene. Molecular formula: C10H12ClNO3. Mole weight: 229.66. Catalog: APB04678.
Ceritinib Impurity 2
Ceritinib Impurity 2. Uses: For analytical and research use. Alternative Names: 4-(5-isopropoxy-2-methyl-3-nitrophenyl)pyridine. Molecular formula: C15H16N2O3. Mole weight: 272.3. Catalog: APB04677.
25g Pack Size. Group: Building Blocks, Catalysts, Organics. Formula: C15H21CeO6 · xH2O. CAS No. 206996-61-4. Prepack ID 90005529-25g. Molecular Weight 437.44. See USA prepack pricing.
Cerium (III) Acetate
Cerium (III) Acetate. Grades: 99.% Extremely High (>=99%). CAS No. 537-00-8. Pack Sizes: Kilogram Quanitites: 10 kg, 50 kg. Order Number: 1401.
www.prochemonline.com
Cerium (III) Acetate
Cerium (III) Acetate. Grades: 99.99% Extremely High (>=99%). CAS No. 537-00-8. Pack Sizes: Gram Quantities: 50 gm, 250 gm. Order Number: 1402.
www.prochemonline.com
Cerium (III) Acetate
Cerium (III) Acetate. Grades: 99.9% Extremely High (>=99%). CAS No. 537-00-8. Pack Sizes: Kilogram Quanitites: 1 kg , 5 kg. Order Number: 1401-1.
www.prochemonline.com
Cerium (III) Acetate
CERIUM (III) ACETATE, SESQUIHYDRATE, 99.9% pure, -6 mesh, (Synonym: Cerous Acetate, Sesquihydrate; Cerium Triacetate, Sesquihydrate), Formula: Ce(OOCCH3)3.1.5H2O. CAS No. 537-00-8. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!
Texas TX
Cerium (III) Acetate Hydrate
Cerium (III) Acetate Hydrate. Grades: 99.99%Extremely High (>=99%). CAS No. 206996-60-3. Pack Sizes: Gram Quantities: 10 g, 50 g. Order Number: 1401-3.
www.prochemonline.com
Cerium (III) Acetate Hydrate
Cerium (III) Acetate Hydrate. Grades: 99.9%Extremely High (>=99%). CAS No. 206996-60-3. Pack Sizes: Gram Quantities: 50 g, 250 g. Order Number: 1401-2.
www.prochemonline.com
Cerium(III) Acetate Hydrate
Cerium(III) Acetate Hydrate. Alternative Names: Cerium(III) Acetate Hydrate. CAS No. 206996-60-3. Molecular formula: C6H9CeO6·Xh2o. Mole weight: 317.25 g/mol. Purity: 98%.