A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grade: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3.
CGS 12066B dimaleate
CGS 12066B dimaleate is a 5-HT1B full agonist, which is 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Uses: Serotonin receptor agonists. Synonyms: CGS 12066B dimaleate; CGS12066B dimaleate; CGS-12066B dimaleate; 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate. Grade: ≥98% by HPLC. CAS No. 109028-10-6. Molecular formula: C17H17F3N4.2C4H4O4. Mole weight: 566.49.
CGS 12066B dimaleate
CGS 12066B dimaleate. Group: Biochemicals. Grades: Purified. CAS No. 109028-10-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Cgs 15696
Cgs 15696 is an adenosine antagonist. Synonyms: 9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one; 9-chloro-2-(furan-2-yl)-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one. Grade: 98% by HPLC. CAS No. 104615-00-1. Molecular formula: C13H7ClN4O2. Mole weight: 286.67.
CGS 15943
CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Synonyms: CGS 15943; CGS15943; CGS-15943; 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine. Grade: ≥99% by HPLC. CAS No. 104615-18-1. Molecular formula: C13H8ClN5O. Mole weight: 285.69.
CGS 15943
CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 104615-18-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100678.
CGS 15943
CGS 15943. Group: Biochemicals. Grades: Purified. CAS No. 104615-18-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGS 19755
CGS 19755 is a potent and competitive NMDA receptor antagonist with anticonvulsant, anxiolytic, analgesic and neuroprotective activity. Synonyms: CGS-19755; CGS 19755; CGS19755; CPDD 0027; CPDD-0027; CPDD0027; Selfotel; cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid. CAS No. 110347-85-8. Molecular formula: C7H14NO5P. Mole weight: 223.17.
CGS 19755
CGS 19755. Group: Biochemicals. Grades: Purified. CAS No. 110347-85-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGS 20625
CGS 20625. Group: Biochemicals. Grades: Purified. CAS No. 111205-55-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGS 20625
CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine receptor agonist (IC50 = 1.3 nM) with no affinity for other neurotransmitter receptor binding sites. Uses: Anti-anxiety drug. Synonyms: CGS 20625; CGS20625; CGS-20625; 5,6,7,8,9,10-Hexahydro-2-(4-methoxyphenyl)cyclohepta[b]pyrazolo[3,4-d]pyridin-3(2H)-one. Grade: ≥99% by HPLC. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.36.
CGS 21680
CGS 21680 is a selective adenosine A2A receptor agonist, with a Ki of 27 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 120225-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-13201.
CGS 21680
CGS 21680, an A2 adenosine receptor selective agonist, has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Uses: Cgs 21680 is an a2 adenosine receptor selective agonist that has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Synonyms: Cgs 21680; CGS-21680; CGS21680; 2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine; UNII-T5HB1E831H; CHEMBL331372. Grade: 95%. CAS No. 120225-54-9. Molecular formula: C23H29N7O6. Mole weight: 499.52.
CGS 21680A
CGS 21680A. Group: Biochemicals. Alternative Names: CGS 21680 hydrochloride; 4- [2- [ [6-Amino-9- (N-ethyl-b-D-ribofuranuronamidosyl) -9H-purin-2-yl] amino] ethyl] benzenepropanoic acid hydrochloride. Grades: Highly Purified. CAS No. 124431-80-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H30ClN7O6. US Biological Life Sciences.
Worldwide
CGS 21680C Sodium Salt
A selective A2A receptor agonist. Uses: A selective a2a receptor agonist. Synonyms: 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic Acid Monosodium Salt. Grade: 95%. CAS No. 120225-64-1. Molecular formula: C23H28N7NaO6. Mole weight: 521.5.
CGS 21680 hydrochloride
CGS 21680 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 124431-80-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGS 21680 Hydrochloride
CGS 21680 Hcl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. Synonyms: CGS 21680 Hydrochloride; CGS21680 Hydrochloride; CGS-21680 Hydrochloride. Grade: >98%. CAS No. 124431-80-7. Molecular formula: C23H29N7O6.HCl. Mole weight: 535.98.
CGS 21680 Hydrochloride
CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a Ki of 27 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 124431-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13201A.
CGS 27023A
CGS 27023A is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9. Synonyms: MMI 270. CAS No. 161314-82-5. Molecular formula: C18H24ClN3O5S. Mole weight: 429.92.
CGS 35066
CGS 35066. Group: Biochemicals. Grades: Purified. CAS No. 261619-50-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CGS 35066
CGS 35066 is a potent endothelin-converting enzyme (ECE) inhibitor with > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 = 22 and 2300 nM, respectively). It blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH). Synonyms: CGS 35066; CGS35066; CGS-35066; α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid; (2S)-3-dibenzofuran-3-yl-2-(phosphonomethylamino)propanoic acid. Grade: ≥99% by HPLC. CAS No. 261619-50-5. Molecular formula: C16H16NO6P. Mole weight: 349.28.
CGS 9343B
CGS 9343B is a calmodulin (CaM) antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity (IC50 = 3.3 nM). It also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR. Synonyms: CGS 9343B; CGS9343B; CGS-9343B; Zaldaride Maleate; 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate. Grade: ≥98% by HPLC. CAS No. 109826-27-9. Molecular formula: C26H28N4O2.C4H4O4. Mole weight: 544.61.
CGS 9343B
CGS 9343B. Group: Biochemicals. Grades: Purified. CAS No. 109826-27-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CH0076989
CH0076989 is a small molecule agonist for CCR3. It activates a number of signalling pathways including chemotaxis and receptor internalisation. Uses: Ch0076989 activates a number of signalling pathways including chemotaxis and receptor internalisation. Synonyms: CH-0076989; CH 0076989; CH0076989; UNII-9E629B19WL; CHEMBL485834; 9E629B19WL; 4-(2-(Benzofuran-4-yl)acetamido)-2-bromo-1-(3-phenylpropyl)pyridin-1-ium bromide. Grade: 98%. CAS No. 54371-52-9. Molecular formula: C24H22Br2N2O2. Mole weight: 530.25.
CH-0793076
CH-0793076, a hexacyclic camptothecin analog and an active drug and major metabolite of TP300, has an inhibitory effect on DNA topoisomerase I with an IC50 of 2.3 μM. It is effective against cells expressing BCRP (breast cancer resistance protein). Synonyms: TP3076; (9S)-9-ethyl-9-hydroxy-1-pentyl-1H,12H-pyrano[3'',4'':6',7']indolizino[1',2':6,5]pyrido[4,3,2-de]quinazoline-10,13(9H,15H)-dione; (9S)-9-Ethyl-9-hydroxy-1-pentyl-1,9,12,15-tetrahydro-10H,13H-pyrano[3'',4'':6',7']indolizino[2',1':5,6]pyrido[4,3,2-de]quinazoline-10,13-dione; 10H,13H-Pyrano[3'',4'':6',7']indolizino[2',1':5,6]pyrido[4,3,2-de]quinazoline-10,13-dione, 9-ethyl-1,9,12,15-tetrahydro-9-hydroxy-1-pentyl-, (9S)-. Grade: ≥98%. CAS No. 534605-78-2. Molecular formula: C26H26N4O4. Mole weight: 458.51.
CH-0793076 TFA
CH-0793076 TFA, a hexacyclic camptothecin analog and an active drug and major metabolite of TP300, has an inhibitory effect on DNA topoisomerase I with an IC50 of 2.3 μM. It is effective against cells expressing BCRP (breast cancer resistance protein). Synonyms: TP3076 TFA; (9S)-9-Ethyl-9-hydroxy-1-pentyl-1,9,12,15-tetrahydro-10H,13H-pyrano[3'',4'':6',7']indolizino[2',1':5,6]pyrido[4,3,2-de]quinazoline-10,13-dione trifluoroacetate (1:1); Acetic acid, 2,2,2-trifluoro-, compd. with (9S)-9-ethyl-1,9,12,15-tetrahydro-9-hydroxy-1-pentyl-10H,13H-pyrano[3'',4'':6',7']indolizino[2',1':5,6]pyrido[4,3,2-de]quinazoline-10,13-dione (1:1). Grade: ≥98%. Molecular formula: C28H27F3N4O6. Mole weight: 572.53.
CH100
CH100 is a Chinese herbal medicine. It is previously used in the treatment of human hepatitis C. Uses: Ch100 is used in the treatment of human hepatitis c. Synonyms: CH 100; CH-100; 2-Propanamine, N-(1-methylethyl)-, (4-chlorophenoxy)acetate; Acetic acid, (4-chlorophenoxy)-, compd. with N-(1-methylethyl)-2-propanamine (1:1). Grade: 98%. CAS No. 51346-20-4. Molecular formula: C14H22ClNO3. Mole weight: 287.78.
CH-102
CH-102 is an isoquinoline derivative. It could inhibit platelet aggregation. Uses: Ch-102 could inhibit platelet aggregation. Synonyms: CH 102; CH102; (3z)-3-imino-8,9-dimethoxy-5,6-dihydro[1,3]thiazolo[4,3-a]isoquinoline-1-carbonitrile; 5,6-Dihydro-3-imino-8,9-dimethoxythiazolo[4,3-a]isoquinoline-1-carbonitrile. Grade: 98%. CAS No. 55393-37-8. Molecular formula: C14H13N3O2S. Mole weight: 287.34.
CH1055
CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1622250-38-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1464.
CH 141
CH 141 is a peripheral vasodilator. Uses: Peripheral vasodilator. Synonyms: 6-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)-3-phenyl-5,6-dihydro-2H-1,2,4-oxadiazine; CH 141; CH-141; CH141; Pthiqdo. Grade: 98%. CAS No. 78279-88-6. Molecular formula: C19-H21-N3-O. Mole weight: 307.39.
CH 150
CH 150 is a bio-active chemical, but detailed information has not been published. Synonyms: CH 150; CH150; CH-150. 3-Ethyl-2,6-dimethyl-4H-pyrido(1,2-a)pyrimidin-4-one. Grade: 98%. CAS No. 70381-44-1. Molecular formula: C12H14N2O. Mole weight: 202.26.
CH-200
CH-200 is used as a new antiarrhythmic drug. It suppressed arrhythmia more effectively than did procainamide and lidocaine in beagle dogs. Uses: Ch-200 is used as a new antiarrhythmic drug. Synonyms: CH200; CH 200; 5-Phenacylthieno(3,2-c)pyridinium chloride; 5-(2-Oxo-2-phenylethyl)thieno(3,2-c)pyridinium chloride. Grade: 98%. CAS No. 64955-45-9. Molecular formula: C15H12ClNOS. Mole weight: 289.78.
CH 223191
CH 223191 is a specific and potent antagonist to the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor that is involved in drug and xenobiotic metabolism. Unlike other AhR antagonists, it does not react with the estrogen receptor and is observed to effect AhR-dependent reporter gene expression in human, mouse, rat, and guinea pig cell lines. CH223191 is reported to exhibit AHR-independent pro-proliferative properties. Group: Biochemicals. Alternative Names: AhR Antagonist, CH223191, AGN-PC-0KP4EW, Aryl hydrocarbon receptor antagonist; 2-methyl-N- [2-methyl-4- [ (2-methylphenyl) diazenyl] phenyl] pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 301326-22-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H19N5, Molecular Weight: 333.4. US Biological Life Sciences.
Worldwide
CH-223191
CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.CH223191 can prevent 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR. These inhibitory effects of CH-223191 prevented the expression of cytochrome P450 enzymes, target genes of the AhR. CH-223191, may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology. Synonyms: CH223191; CH-223191; CH 223191. Grade: >98%. CAS No. 301326-22-7. Molecular formula: C19H19N5O. Mole weight: 333.39.
CH-223191
CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR).CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301326-22-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12684.
CH-223191
CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM. Group: Inhibitors. CAS No. 301326-22-7. Pack Sizes: 10mg. Product ID: S7711. Formula: C19H19N5O. Smiles: CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
CH 275
CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst1) with a Ki of 52 nM[1]. CH 275 acts as a potent and selective sst1 agonist (IC50=30.9 nM) and also displays IC50 values of 345 nM, >1 μM, >10 μM, >10 μM for human sst3, sst4, sst2 and sst5, respectively[2]. CH 275 can be used for the research of alzheimers disease[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 174688-78-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1206.
CH 275
CH 275 is a potent somatostatin receptor 1 (sst1) agonist (IC50 = 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). It attenuates somatostatin release in the rat nucleus accumbens. Synonyms: CH 275; CH275; CH-275. CAS No. 174688-78-9. Molecular formula: C74H96N14O15S2. Mole weight: 1485.8.
CH3NH3PbBr3; Perovskite CH3NH3PbBr3 Powder, >99%
CH3NH3PbBr3; Perovskite CH3NH3PbBr3 Powder, >99%. CAS No. 69276-13-7.
CH3NH3PbICl2(MAPbICl2 )Methylammonium Lead Chloride Iodide, >99%
CH3NH3PbICl2(MAPbICl2 )Methylammonium Lead Chloride Iodide, >99%. CAS No. 1472068-56-6.
CH3OCO-D-CHA-Gly-Arg-pNA acetate
CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 80895-10-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153829.
CH-401Na
CH-401Na is a bio-active chemical compound. Synonyms: CH 401Na; CH-401-Na; CH401-Na; 1-(2-Hydroxy-4-(3-sulfopropyloxy)phenyl)-3-(3-hydroxy-4-methoxyphenyl)-1-propanone sodium salt. Grade: 98%. CAS No. 59881-19-5. Molecular formula: C19H21NaO8S. Mole weight: 432.42.
CH5015765 is a novel potent and selective HSP90 inhibitor. CH5015765, which showed high affinity for Hsp90 and antitumor activity in human cancer xenograft mouse models. Synonyms: CH-5015765; CH 5015765; 4-(5-chloro-1,3-dihydrobenzo[de]isochromen-6-yl)-6-(methylthio)-1,3,5-triazin-2-amine. Grade: 98%. CAS No. 959766-47-3. Molecular formula: C16H13ClN4OS. Mole weight: 344.82.
CH5132799
CH5132799 is a novel class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K; (IC(50)=0.014 uM). In human tumor cell lines with PI3K pathway activation, CH5132799 showed potent antiproliferative activity. CH5132799 is orally available and showed significant antitumor activity in PI3K pathway-activated human cancer xenograft models in mice. Synonyms: CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799. CAS No. 1007207-67-1. Molecular formula: C15H19N7O3S. Mole weight: 377.423.
CH5137291
CH5137291 is a potent androgen receptor (AR) pure antagonist which did not produce the agonist metabolite with AR nuclear translocation-inhibiting activity. It inhibits the growth of castration-resistant prostate cancer cells. It offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Uses: Ch5137291 offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Synonyms: CH-5137291; CH 5137291; CH5137291; UNII-A5ZX7J376H; A5ZX7J376H; CHEMBL1290098. 6-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)pyridine-2-sulfonamide. Grade: >98 %. CAS No. 1043446-39-4. Molecular formula: C18H14F3N5O3S2. Mole weight: 469.46.
CH5138303
CH5138303 is a novel and potent Hsp90 inhibitor. CH5138303 showed high binding affinity for N-terminal Hsp90α (Kd = 0.52 nM) and strong in vitro cell growth inhibition against human cancer cell lines (HCT116 IC50=0.098 μM, NCI-N87 IC50=0.066 μM) and also displayed high oral bioavailability in mice (F = 44.0%) and potent antitumor efficacy in a human NCI-N87 gastric cancer xenograft model (tumor growth inhibition=136%). Synonyms: CH-5138303; CH 5138303. Grade: >98%. CAS No. 959763-06-5. Molecular formula: C19H18ClN5O2S. Mole weight: 415.90.
CH5164840
CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations. Synonyms: CH5164840; CH-5164840; CH 5164840. Grade: 98%. CAS No. 1052645-73-4. Molecular formula: C19H23N5O2S. Mole weight: 385.49.
CH5424802 analog
CH5424802 analog is a selective inhibitor of ALK capable of blocking the resistant gatekeeper mutant. Synonyms: CH-5424802 analog; 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile. CAS No. 1256577-71-5. Molecular formula: C28H30N4O2. Mole weight: 454.56.
CH5424802 Hydrochloride
CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Synonyms: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. Grade: >98%. CAS No. 1256589-74-8. Molecular formula: C30H35ClN4O2. Mole weight: 519.08.
CH 5450
Z-Ile-Glu-Pro-Phe-Ome is a peptide inhibitor of human heart chymase which is a chymotrypsin-like enzyme that converts angiotensin I to angiotensin II. Synonyms: ZIEPF-Ome; N-benzyloxycarbonyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-L-phenylalanine methyl ester; Cbz-Ile-Glu-Pro-Phe-OMe; CH5450; CH-5450. Grade: ≥95%. CAS No. 252557-97-4. Molecular formula: C34H44N4O9. Mole weight: 652.73.
Ch55
Ch55 is a potent synthetic retinoid. Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC50 of 200 nM. Ch55 can be used for cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110368-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107397.
Ch 55
Ch 55. Group: Biochemicals. Grades: Purified. CAS No. 110368-33-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CH 55
CH 55 is an impurity of Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: Ch55; Ch-55; Ch 55. 4-[(1E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]benzoic Acid; (E)-4-[3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]-benzoic Acid; Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-. Grade: ≥98% by HPLC. CAS No. 110368-33-7. Molecular formula: C24H28O3. Mole weight: 364.48.
Ch55-O-C3-NH2
Ch55-O-C3-NH2 is a Ch 55-based ligand which targets RAR. It binds to cIAP1 ligand Bestatin via a linker to form SNIPER. Synonyms: RAR ligand 1. CAS No. 144298-98-6. Molecular formula: C27H35NO4. Mole weight: 437.57.
CH6953755
YES proto-oncogene 1 has a significant impact on tumor growth. YES1 kinase inhibition by CH6953755 led to antitumor activity against YES1-amplified cancers in vitro and in vivo. Synonyms: CH 6953755. Grade: 98%. CAS No. 2055918-71-1. Molecular formula: C26H22F2N6O4S. Mole weight: 552.55.
CH6953755
CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055918-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135299.
CH7057288
CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB, and TRKC respectively. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Synonyms: N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide; HY-107362; CS-0028214; RCH. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.67.
CH7233163
CH7233163 is a non-covalent ATP-competitive inhibitor of EGFR-tyrosine kinase. CH7233163 shows potent antitumor activities against tumor with EGFR-Del19/T790M/C797S in vitro and in vivo. Synonyms: N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine. Molecular formula: C31H34F3N9O3S. Mole weight: 669.72.
CH7233163
CH7233163 is a noncovalent ATP-competitive inhibitor for EGFR-Del19/T790M/C797S. CH7233163 can overcome Osimertinib (HY-15772)-Resistant EGFR-Del19/T790M/C797S mutation. CH7233163 blocks the EGFR phosphorylation in the Del19/T790M/C797S_NIH3T3 cells. CH7233163 has antitumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923365-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137191.
ChaC1
ChaC1 is isolated from Chassalia chartacea. It plays a role on mammalian cells and cancer cells.
ChaC10
ChaC10 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells.
ChaC11
ChaC11 is isolated from Chassalia chartacea. It is against Escherichia coli.
ChaC2
ChaC2 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells.
ChaC4
ChaC4 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells.
ChaC7
ChaC7 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on Gram-negative bacteria, mammalian cells and cancer cells.
ChaC8
ChaC8 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on Gram-negative bacterial, mammalian cells and cancer cells.
Cha De Bugre Powder
Cha De Bugre Powder.
CA, FL & NJ
Chaetiacandin
It is produced by the strain of Monochaetia dimorphospora(Papulacadin). The activity of Chaetiacandin against Candida albicans was stronger than amphotericin B and 5-FC. Synonyms: LS-71333; D-Glucitol, 1,5-Anhydro-1-C-(2,4-Dihydroxy-6-(Hydroxymethyl)Phenyl)-4-O-(6-O-(1-Oxo-2,4-Decadienyl)-Beta-D-Galactopyranosyl)-, 3-(7-Hydroxy-2,4,8,10-Tetradecatetraenoate). CAS No. 96989-32-1. Molecular formula: C43H60O16. Mole weight: 832.92.
Chaetoatrosin
It is produced by the strain of Chaetomium atrobrunneum F449. Chaetoatrosin inhibits chitin synthase of IC50 of 104 ?/mL. Chaetoatrosin has antifungal activity including Pyricularia oryzae, Botrytis cinerea, Cryptococcus neoformans, Trichophyton mentagrophytea and so on. Synonyms: Chaetoatrosin A; chaetoatrosin-a; SCHEMBL12800163. Molecular formula: C14H14O5. Mole weight: 262.26.