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| Product | Description | |
|---|---|---|
| Clozapine-d4 | Clozapine-d 4 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: HF 1854-d4. CAS No. 204395-52-8. Pack Sizes: 1 mg. Product ID: HY-14539S2. |  |
| Clozapine-d8 (8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine, HF-1854-d8, Liponex-d8) | An antipsychotic.A representative lot was 92% d8, 8% d7. Group: Biochemicals. Alternative Names: 8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine; HF-1854-d8; Liponex-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Clozapine Impurity 6 | Clozapine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025951-76-1. Molecular formula: C20H21ClN4O. Mole weight: 368.86. Catalog: APB1025951761. |  |
| Clozapine N-oxide | Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34233-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366. | |
| Clozapine N-oxide dihydrochloride | Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250025-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366A. | |
| Clozapine (Standard) | Clozapine (Standard) is the analytical standard of Clozapine. This product is intended for research and analytical applications. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854 (Standard). CAS No. 5786-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14539R. | |
| CLP257 | CLP257 is a selective K+-Cl cotransporter KCC2 activator with an EC50 of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181081-71-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110143. | |
| CLP257 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CLP 257 | CLP 257. Group: Biochemicals. Grades: Purified. CAS No. 1181081-71-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CLP 257 | CLP 257 has been found to be a KCC2 K+-Cl- cotransporter activator and could alleviates hypersensitivity in rats with peripheral nerve injury. Synonyms: CLP 257; CLP-257; CLP257; (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone. Grade: ≥98% by HPLC. CAS No. 1181081-71-9. Molecular formula: C14H14FN3O2S. Mole weight: 307.34. |  |
| CLP290 | CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181083-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103023. | |
| CLP290 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CLP-3094 | CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). It inhibits AR transcriptional activity (IC50 = 4 μM). CLP-3094 is also a selective, potent GPR142 antagonist. Synonyms: 2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole; 1H-Benzimidazole, 2-[[2-(4-chlorophenoxy)ethyl]thio]-. Grade: ≥95%. CAS No. 312749-73-8. Molecular formula: C15H13ClN2OS. Mole weight: 304.79. | |
| Cl-PEG4-acid | Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 158553-98-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W096129. | |
| CLPP (240-248) | CLPP is a protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. It has low peptidase activity in the absence of CLPX. Synonyms: Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit (240-248); ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial (240-248). | |
| CLS-011A | CLS-011A is a small molecule used as an antineoplastic and eye disorder therapy. Study indicated its excellent tolerance. Uses: Antineoplastic and eye disorder therapy. Synonyms: CLS 011A. | |
| Cl--transporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. An animal and plant enzyme involved in the import of chloride anions. Group: Enzymes. Synonyms: Cl--translocating ATPase; Cl--motive ATPase. Enzyme Commission Number: EC 3.6.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4648; Cl--transporting ATPase; EC 3.6.3.11; Cl--translocating ATPase; Cl--motive ATPase. Cat No: EXWM-4648. |  |
| Cl-Trt-Resin | Cl-Trt-Resin. Synonyms: Tritylchloride Resin. | |
| Cluster Dextrin | Cluster Dextrin. |  CA, FL & NJ |
| Clusterin (nuclear form) mouse | recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| CLZ-8 | CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a K i of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 678158-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122627. | |
| CM03 | CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2101208-44-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121862. | |
| CM037 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grade: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| CM 10 | CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grade: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| CM-24 | CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569. | |
| CM-272 | CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1846570-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101925. | |
| CM-272 | CM-272 is a first-in-class reversible and substrate-competitive dual inhibitor of G9a (GLP) and DNMTs. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death in models of haematological neoplasia. Synonyms: CM 272; CM272. CAS No. 1846570-31-7. Molecular formula: C28H38N4O3. Mole weight: 478.63. | |
| CM-3 | CM-3 is a synthetic construct with antibacterial activity. | |
| CM-352 | CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R)-N-hydroxy-2-((4-(4-(methylcarbamoyl)phenoxy)phenyl)sulfonyl)-8-azaspiro[4.5]decane-2-carboxamide. Grade: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57. | |
| CM398 | CM398 has preferential affinity for sigma-2 receptor compared with sigma-1 receptor and at least four other neurotransmitter receptors sites, including the norepinephrine transporter. Synonyms: 1-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1h)-yl)butyl)-3-methyl-1h-benzo[d]imidazol-2(3h)-one. Grade: 98%. CAS No. 1121931-70-1. Molecular formula: C23H29N3O3. Mole weight: 395.49. | |
| CM398 | CM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628. | |
| CM-579 trihydrochloride | CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT, with IC50s of 16 nM and 32 nM, respectively. It has potent in vitro cellular activity in a wide range of cancer cells. Synonyms: 6-Methoxy-2-(5-methyl-2-furyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinolinamine trihydrochloride; 4-Quinolinamine, 6-methoxy-2-(5-methyl-2-furanyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrochloride (1:3). Grade: ≥95%. Molecular formula: C29H43Cl3N4O3. Mole weight: 602.04. | |
| CMA | CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grade: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| CMC2.24 | CMC2.24 is an orally active tricarbonylmethane agent. It is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 μM. Synonyms: TRB-N0224. Grade: 96%. CAS No. 1255639-43-0. Molecular formula: C26H21NO5. Mole weight: 427.45. | |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. CAS No. 9004-32-4. Product ID: PE-0150. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Binder Excipients; CMC-Na; PE-0150; 9004-32-4; 9004-32-4. Purity: 0.9972. Synonym(s): Sodium carboxymethyl cellulose. Storage: 3 years -20°C powder. |  |
| CMD178 | CMD178 is a lead peptide that can sustainably reduce the expression of Foxp3 and STAT5 induced by IL-2/ S IL-2Rα signal. CMD178 is also a STAT5 inhibitor and inhibits the development of Treg cells. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester; RFKFY-OBn; CMD 178; CMD-178. Grade: ≥98%. CAS No. 2703745-80-4. Molecular formula: C46H59N9O7. Mole weight: 850.03. | |
| CMD178 TFA | CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grade: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05. | |
| CM-Dextran sodium salt | CM-Dextran sodium salt. Group: Natural polymers and biopolymerspolysaccharide. CAS No. 39422-83-8. |  |
| cMet Active human | recombinant, expressed in baculovirus infected insect cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| c-Met-IN-1 | c-Met-IN-1, a potent and selective c-Met inhibitor (IC50 = 1.1 nM), has antitumor activity. Synonyms: N-[3-Fluoro-4-[6-methoxy-7-[3-(4-methylpiperazino)propoxy]quinoline-4-yloxy]phenyl]-1-(2-methoxyphenyl)-1H-imidazole-4-carboxamide; 1H-Imidazole-4-carboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-4-quinolinyl]oxy]phenyl]-1-(2-methoxyphenyl)-. Grade: ≥95%. CAS No. 2084836-84-8. Molecular formula: C35H37FN6O5. Mole weight: 640.70. | |
| c-Met-IN-2 | c-Met-IN-2, a potent, selective and orally available c-Met inhibitor (IC50 = 0.6 nM), has antitumor activity. Synonyms: 2-[4-(1-{1-[7-Fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl}-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl]ethanol; 1H-Pyrazole-1-ethanol, 4-[1-[1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl]-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-. Grade: ≥95%. CAS No. 1635406-73-3. Molecular formula: C24H21FN10O. Mole weight: 484.49. | |
| c-Met inhibitor 1 | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grade: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41. | |
| c-Met Kinase Inhibitor III | The c-Met Kinase Inhibitor III controls the biological activity of c-Met. Group: Fluorescence/luminescence spectroscopy. | |
| c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) | c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) | c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) | c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) | c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met/RON Dual Kinase Inhibitor - CAS 913376-84-8 | The c-Met/RON Dual Kinase Inhibitor, also referenced under CAS 913376-84-8, controls the biological activity of c-Met/RON. Group: Fluorescence/luminescence spectroscopy. | |
| CMF019 | CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1586787-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103080. | |
| CMG-101 | CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101. | |
| CM-H2DCFDA | CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 850013-49-9. Pack Sizes: 50 ?g. Product ID: HY-D1713. | |
| CMHPG | CMHPG. |  |
| CMI-392 | CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15. | |
| CMI-977 | CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grade: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34. | |
| CMIT/MIT | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| CMK | CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grade: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82. | |
| CMK | CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Group: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101. | |
| CMK-3 | CMK-3. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-216. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane, CM-32 armoured vehicle. |  |
| CMK-8 | CMK-8. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-161. Alfa Chemistry ISO 9001:2015 Certified. Categories: CMA 8. | |
| CMLD012072 | CMLD012072, an amidino-rocaglates, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with strong antitumor activity. It can induce RNA to clamp eIF4A1 and eIF4A2. Synonyms: Methyl (3aR,4R,5S,5aR,10bR)-2-cyclopropyl-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate; 1H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 2-cyclopropyl-3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-. Grade: ≥95%. CAS No. 2368900-33-6. Molecular formula: C32H32N2O7. Mole weight: 556.61. | |
| CMLD012073 | CMLD012073, an amidino-rocaglates and a potent eukaryotic initiation factor 4A (eIF4A) inhibitor, inhibits NIH/3T3 cells growth with an IC50 of 10 nM. It inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A). Synonyms: 3H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-; Methyl (3aR,4R,5S,5aR,10bR)-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate. Grade: ≥97%. CAS No. 2368900-32-5. Molecular formula: C30H30N2O7. Mole weight: 530.57. | |
| CML-d2 | CML-d2. Synonyms: N-epsilon-carboxy[D2]methyl-L-Lysine; H-L-Lys(Cm)-OH-d2; H-Lys(Cm)-OH-d2; (S)-2-amino-6-(carboxy[D2]methylamino)hexanoic acid. Molecular formula: C8H14D2N2O4. Mole weight: 206.24. | |
| CMLD-2 | CMLD-2 is an inhibitor of HuR-ARE interaction. CMLD-2 induces apoptosis and exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Synonyms: 5,7-dimethoxy-8-(1-(4-methoxyphenyl)-3-oxo-3-(pyrrolidin-1-yl)propyl)-4-phenyl-2H-chromen-2-one. Grade: 98%. CAS No. 958843-91-9. Molecular formula: C31H31NO6. Mole weight: 513.58. | |
| CMLD-2 | CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 958843-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-124828. | |
| Cm-p1 | Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grade: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
| CMP-5 | CMP5 is a potent, selective and specific inhibitor of PRMT5, but has no activity against PRMT1, PRMT4 and PRMT7 enzymes. CMP5 selectively blocks S2Me-H4R3 by inhibiting the activity of PRMT5 methyltransferase on histone preparations. It prevents epstein-barr virus (EBV)-driven B-lymphocyte transformation, but does not affect normal B cells. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine; PRMT5-IN-5; N-[(9-ethyl-9H-carbazol-3-yl)methyl]-N-(2-pyridinylmethyl)amine; 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-. Grade: ≥98%. CAS No. 880813-42-3. Molecular formula: C21H21N3. Mole weight: 315.41. | |
| CMP-5 | CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880813-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120137. | |
| CMP-5 2HCl | CMP-5 2HCl is a repellent. The EC100 of CMP-5 2HCl in vitro against H. contortus is 5 μM. Synonyms: 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-,hydrochloride (1:2). Grade: >98.0%. CAS No. 2309409-79-6. Molecular formula: C21H23Cl2N3. Mole weight: 388.34. | |
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