A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Citropin-2.1.3 is isolated from Litoria citropa. It has bacteriostatic action for Gram-positive bacteria.
citrullinase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. Group: Enzymes. Synonyms: citrulline ureidase; citrulline hydrolase; L-citrulline 5-N-carbamoyldihydrolase. Enzyme Commission Number: EC 3.5.1.20. CAS No. 59088-17-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4410; citrullinase; EC 3.5.1.20; 59088-17-4; citrulline ureidase; citrulline hydrolase; L-citrulline 5-N-carbamoyldihydrolase. Cat No: EXWM-4410.
Citrus Aurantium Dulcis Sweet Orange Peel Wax
Citrus Aurantium Dulcis (Sweet Orange Peel) Wax is a natural wax derived from the peel of sweet oranges. It is obtained by cold-pressing the peels and then filtering the resulting wax. The wax contains properties that make it a great emollient and skin conditioning agent. It is used in personal care products like lipsticks, lip balms, creams, lotions, and other similar products as an alternative to synthetic waxes. The sweet orange peel wax is rich in antioxidants, Vitamin C and other nutrients which make it an excellent ingredient for skin nourishment and protection. It has a smooth texture and provides a silky feel to the skin, making it a popular choice in cosmetic formulations. Additionally, the wax is vegan and cruelty-free, making it very attractive to consumers who seek natural and sustainable products. CAS No. 8028-48-6. Product ID: CI-SC-0488. Alfa Chemistry - ISO 9001:32057 Certified.
Citrus Aurantium Extract
Citrus Aurantium Extract. Applications: 1. applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of alcoholicbeverage, dessert foods and savory foods. 2. applied in cosmetics, it can added into toothpaste and mouth wash. 3. applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form. Group: Others. Purity: Synephrine 4%, 6%, 10%, 30%, 60%, 90%, 95% HPLC. Appearance: Yellow-brown powder / Milk white powdered extract. Source: Synephrine is the main "active" compound found in the fruit of a plant called Citrus aurantium. The fruit is also known as zhi shi (in traditional Chinese medicine), and as green orange, sour orange and bitter orange in other parts of the world. Synephrine is chemically very similar to the ephedrine and pseudo-ephedrine found in many OTC cold/allergy medications and in a number of weight loss and energy supplements which contain Ma Huang. Citrus Aurantium Extract; Citrua aurantium L. Cat No: EXTC-178.
Citrus Aurantium P.E. 10:1
Citrus Aurantium P.E. 10:1.
CA, FL & NJ
Citrus Aurantium P.E. 90% Diosmin
Citrus Aurantium P.E. 90% Diosmin.
CA, FL & NJ
Citrus Bioflavonoids 50%
Citrus Bioflavonoids 50%.
CA, FL & NJ
Citrus Paradisi Seed Extract
Citrus Paradisi Seed Extract. CAS No. 90045-43-5. Product ID: CI-OT-0117. Alfa Chemistry - ISO 9001:32057 Certified.
Citrus red 2
Citrus red 2 (CI Solvent red 80) is a synthetic dye with coloring power and antioxidant activity. Citrus red 2 can be used in food and cosmetics to provide a bright color to the product. Citrus red 2 is also used as a reference substance for testing and analysis in certain situations. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C.I. Solvent red 80. CAS No. 6358-53-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W775174.
The enzyme is a component of EC 4.1.3.6 {[citrate (pro-3S)-lyase]}and EC 2.3.3.8 [ATP citrate synthase]. Also acts on (3S)-citryl thioacyl-carrier protein. Group: Enzymes. Synonyms: (3S)-citryl-CoA oxaloacetate-lyase. Enzyme Commission Number: EC 4.1.3.34. CAS No. 131095-35-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4911; citryl-CoA lyase; EC 4.1.3.34; 131095-35-7; (3S)-citryl-CoA oxaloacetate-lyase. Cat No: EXWM-4911.
Cituline malate 2:1
Cituline malate 2:1. CAS No. 54940-97-5. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Civettone. CAS No. 542-46-1. FEMA No. 3425. Kosher: Y. VIGON Item # 502963. Categories: Speciality Ingrdients Suppliers.
America & Internationally
Ciwujianoside C3
Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114906-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4134.
Ciwujiatone
Ciwujiatone is purified from the herbs of Kalimeris integrifolia. Ciwujiatone shows significant activities against colon cancer cell lines SW480 and SW620. Synonyms: (4-hydroxy-3,5-dimethoxyphenyl)-[(3R,4R,5S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methanone. Grade: 97.0%. CAS No. 218901-26-9. Molecular formula: C22H26O9. Mole weight: 434.44.
Cixutumumab
Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMC-A12; NSC742460. CAS No. 947687-12-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99189.
Cixutumumab
Cixutumumab is a humanized anti-IGF-1R monoclonal antibody for the treatment of solid tumors. Cixutumumab selectively binds to membrane-bound IGF-1R, preventing the binding of the natural ligand IGF-1 and the subsequent activation of PI3K/AKT signaling pathway. Synonyms: IMC-A12; NSC742460. CAS No. 947687-12-9.
Cizutamig
Cizutamig (CND-106) is a bispecific T-cell engager targeting BCMA and CD3. Cizutamig exhibits immunostimulatory and anti-tumor activities. Cizutamig can be used in research related to relapsed or refractory multiple myeloma and systemic lupus erythematosus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CND-106; EMB-06. CAS No. 2919209-65-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990980.
CJ 033466
CJ 033466. Group: Biochemicals. Grades: Purified. CAS No. 519148-48-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CJ 033466
CJ 033466 has been found to be a partial and selective 5-HT4 agonist and could exhibit gastroprokinetic effects in vivo. Synonyms: CJ 033466; CJ033466; CJ-033466; 5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-carboxamide. Grade: ≥98% by HPLC. CAS No. 519148-48-2. Molecular formula: C19H28ClN5O. Mole weight: 377.91.
CJ-12371
CJ-12371 is a DNA gyrase inhibitor originally isolated from N 983-46. It was resistant to Gram-positive bacteria, including Staphylococcus, Streptococcus, Enterococcus and Ciprofloxacin, with MIC of 25-100 μg/mL. Synonyms: AC1LAGH1; (4S)-3,4-Dihydro-2H-spiro[naphthalene-1,2'-naphtho[1,8-de][1,3]dioxine]-4,5-diol. Molecular formula: C20H16O4. Mole weight: 320.34.
CJ-12372
CJ-12372 is an inhibitor of DNAgyrase produced by an unidentified fungus N 983-46. It has anti-Gram-positive bacteria, including Staphylococcus, Streptococcus, Enterococcus and Ciprofloxacin (Ciprofloxacin) drug-resistant bacteria activity, with MIC of 25-100 μg/mL. CAS No. 157110-17-3. Molecular formula: C20H16O5. Mole weight: 336.34.
CJ-12373
CJ-12373 is produced by the strain of Penicillum sp. CL22557. It inhibits the superhelix and relaxation mediated by DNA gyrase, not form cracking intermediates, also inhibits the relaxation mediated by eukaryotic topoisomerase II. And it also has anti-Gram-positive bacteria, including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes and Streptococcus agalactiae, which are sensitive and resistant to ciprofloxacin. Molecular formula: C17H24O6. Mole weight: 324.37.
CJ-12954
It is produced by the strain of Phanerochaete velutina CL6387. CJ-12954 has strong anti-helicobacter pylori activity. Synonyms: (3R)-5,7-Dimethoxy-3-{6-[(2R,5R)-7-methyl-1,6-dioxaspiro[4.4]non-2-yl]hexyl}-2-benzofuran-1(3H)-one. Molecular formula: C24H34O6. Mole weight: 418.52.
CJ-13014
It is produced by the strain of Phanerochaete velutina CL6387. CJ-13014 is stereoisomer with CJ-12954 and it has strong anti-helicobacter pylori activity. Molecular formula: C24H34O6. Mole weight: 418.52.
CJ-13136
CJ-13136 is originally isolated from Pseudonocardia sp. CL38489. It has highly selective anti-helicobacter pylori activity. Synonyms: 3-Methyl-2-((2E)-3,7-dimethyl-2,6-octenyl)quinoline-4(1H)-one; SCHEMBL14519803. Molecular formula: C20H25NO. Mole weight: 295.42.
CJ-13610
CJ-13610 is an inhibitor of 5-lipoxygenase (5-LO). It inhibits 5-LO product formation in human polymorphonuclear leukocytes (PMNLs) challenged with A23187 in vitro. It also inhibits 5-LO product formation induced by phosphorylation in PMNLs and HeLa cells. Synonyms: 4-[3-[4-(2-methylimidazol-1-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide; Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide. Grade: ≥98%. CAS No. 179420-17-8. Molecular formula: C22H23N3O2S. Mole weight: 393.5.
CJ-13,610
CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid. Uses: Scientific research. Category: Signaling pathways. CAS No. 179420-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106200.
CJ-13,610 hydrochloride
CJ-13,610 hydrochloride is a nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs. Synonyms: 2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-, hydrochloride (1:1). CAS No. 179420-27-0. Molecular formula: C22H24ClN3O2S. Mole weight: 429.96.
CJ-13981
It is originally isolated from CL15036. CJ-13981 inhibited SSASE in rat liver and human liver with IC50 of 4.4 μmol/L and 2.8 μmol/L respectively. Molecular formula: C18H30O6. Mole weight: 342.43.
CJ 14258
CJ 14258, produced by the strain of Hericium ramosum CL 24240, is a selective binding inhibitor of κ-opioid receptor with IC50 of 32 μmol/L. Synonyms: Antibiotic CJ 14258; (12S,15S)-15-O-Demethyl-10,29-dideoxy-11,12-dihydro-striatin C. Molecular formula: C25H38O6. Mole weight: 434.56.
CJ-14877
It is originally isolated from Marasmiellus sp. CL21624. CJ-14877 inhibited human blood interleukin-1β (IL-1β) production induced by lipoglycan (LPS) with an IC50 of 0.1 μmol/L. Synonyms: 2-Pyridinecarboxylic acid, 5-[(1S,2S)-1,2-dihydroxypropyl]-, methyl ester. Molecular formula: C10H13NO4. Mole weight: 211.21.
CJ-14897
It is originally isolated from Marasmiellus sp. CL21624. CJ-14897 inhibited human blood interleukin-1β (IL-1β) production induced by lipoglycan (LPS) with an IC50 of 0.059 μmol/L. Synonyms: (+)-CJ-14897; 2-Pyridinecarboxylic acid, 5-((1S,2S)-2-(acetyloxy)-1-hydroxypropyl)-, methyl ester; UNII-10M04QP59K. CAS No. 377755-95-8. Molecular formula: C12H15NO5. Mole weight: 253.25.
CJ-15161
CJ-15161 is a κ-opioid receptor agonist. Synonyms: CJ 15161; CJ15161; 4-(((S)-2-((S)-3-Hydroxypyrrolidin-1-yl)-1-phenylethyl)(methyl)amino)-N-propylbenzamide. CAS No. 204970-97-8. Molecular formula: C23H31N3O2. Mole weight: 381.52.
CJ-15183
CJ-15183 is originally isolated from Aspergillus aculeatus CL38916. It has strong inhibitory activity against rat liver, human liver and Candida albicans SSase, and has antifungal activity against filamentous fungi and yeast-like fungi. Molecular formula: C28H38O13. Mole weight: 582.59.
CJ-15208
CJ-15208 is produced by the strain of Ctenomyces serratus. It selectively inhibits κ-opioid receptor binding with an IC50 of 47 nmol/L. Synonyms: (3S,6S,9S,14aR)-6-((1H-indol-3-yl)methyl)-3,9-dibenzyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone; c[L-Phe-D-pro-L-Phe-L-trp]. CAS No. 210236-47-8. Molecular formula: C34H35N5O4. Mole weight: 577.67.
CJ 15544
CJ 15544 is a potent κ-opioid receptor antagonist from a fungus, Hericium ramosum CL 24240. Synonyms: Antibiotic CJ 15544. Molecular formula: C25H34O6. Mole weight: 430.53.
CJ-15696
CJ-15696 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has moderate activity against gram-positive bacteria, including drug-resistant bacteria. Molecular formula: C19H19NO3. Mole weight: 309.36.
CJ-15801
It is originally isolated from Seimatosporium sp. CL28611. CJ-15801 has only anti-MRSA activity with MIC of 6.25-50 μg/mL. Synonyms: CJ-15,801; BDBM50285609; 3-[[(R)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino]acrylic acid. Molecular formula: C9H15NO5. Mole weight: 217.22.
CJ-16169
CJ-16169 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria. Molecular formula: C19H21NO3. Mole weight: 311.37.
CJ-16170
CJ-16170 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria. Molecular formula: C19H21NO3. Mole weight: 311.37.
CJ-16173
CJ-16173 is a furopyridine antibiotic produced by the strain of Cladobotryum varium CL12284. It has weak activity against gram-positive bacteria. Molecular formula: C19H19NO4. Mole weight: 325.36.
CJ-16367
It is originally isolated from CL39457. CJ-16367 is mainly resistant to Gram-positive bacteria, including multi-drug resistant strains, but its activity is weak. Molecular formula: C23H31NO5. Mole weight: 401.49.
CJ-17572
It is produced by the strain of Pezicula sp. CJ-11877. CJ-17572 has anti-MRSA and Enterococcus faecalis activity with MIC of 10-20 μg/mL. Synonyms: 3-[hydroxy(1,2,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)methylidene]-5-(1-hydroxyethyl)-1-methylpyrrolidine-2,4-dione. Molecular formula: C21H31NO4. Mole weight: 361.47.
CJ-17665
CJ-17665 is produced by the strain of Aspergillus ochraceus. It inhibits growth of multi-drug resistant MRSA, Streptococcus pyogenes and Enterococcus faecalis with MIC of 12.5, 12.5 and 25 μg/mL, respectively. Molecular formula: C26H33N3O4. Mole weight: 451.56.
CJ-19784
CJ-19784 is an antibiotic which is mainly resistant to Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. It is produced by the strain of Acanthostigmella sp. CL-12082. Synonyms: 4H-1-Benzopyran-4-one,2-(3-bromo-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy. CAS No. 399509-71-8. Molecular formula: C18H15BrO7. Mole weight: 423.21.
CJ-21058
CJ-21058 is a SecA inhibitor originally isolated from CL47745. It shows antiprotozoal effects (IC50 = 7 μM, T. brucei) and inhibits post-translational protein transport into the endoplasmic reticulum. It shows antibacterial and antifungal effects in vivo. Synonyms: CHEMBL565009; (5R,Z)-3-(Hydroxy((1R,2S,6S,8aS)-1,3,6-trimethyl-2-((E)-prop-1-en-1-yl)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)methylene)-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione. Grade: >98% by HPLC. CAS No. 405072-57-3. Molecular formula: C23H33NO4. Mole weight: 387.51.
CJ-21164
It is produced by the strain of Chloridium sp. CL48903. The IC50 of CJ-21164 inhibiting G6Pase in rat liver microsomes was 1.6 μmol/L. Synonyms: CHEMBL3218304. Molecular formula: C38H37ClO14. Mole weight: 753.14.
CJ-2360
CJ-2360 is a potent and orally active ALK with IC50s of 2.2, 4.0, 8.8, 6.3, and 8.9 nM against wild-type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ-2360 displays potenty activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated. CAS No. 2226742-61-4. Molecular formula: C27H30FN5O2. Mole weight: 475.56.
CJ28
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3047118-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-157528.
CJ-42794
CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist. It inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It competitively antagonized cAMP accumulation with a pA2 value of 8.7 in HEK293 cells overexpressing rat prostanoid EP4 receptors. It did not exhibit any remarkable binding to 65 additional proteins, including GPCRs, enzymes, and ion channels. It reversed the inhibitory effects of PGE2 on LPS-induced TNFα production in a concentration-dependent manner. It has excellent pharmacological properties that make it a useful tool for exploring the physiological role of EP4 receptors. Uses: Cj-42794 has excellent pharmacological properties that make it a useful tool for exploring the physiological role of ep4 receptors. Synonyms: CJ-042794; CJ 042794; CJ042794; RQ-00015986, RQ-15986. 4-[(1S)-1-[[5-chloro-2-(4-fluorophenoxy)benzoyl]amino]ethyl]benzoic acid; (S)-4-(1-(5-chloro-2-(4-fluorophenoxy)benzaMido)ethyl)benzoic acid; CJ-042794; 4-((S)-1-(2-(4-fluorophenoxy)-5-chlorobenzamido)ethyl)benzoic acid. Grade: >98%. CAS No. 847728-01-2. Molecular formula: C22H17ClFNO4. Mole weight: 413.83.
CJ463
CJ463 is a potent ans selective Urokinase (uPA) inhibitor, which plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis. It may be a novel agent for treatment of lung cancer. Uses: Cj463 may be a novel agent for treatment of lung cancer. Synonyms: CJ-463; CJ 463; CJ463. (S)-N-(4-carbamimidoylbenzyl)-3-hydroxy-2-((R)-3-hydroxy-2-((phenylmethyl)sulfonamido)propanamido)propanamide. Grade: 98%. CAS No. 600142-19-6. Molecular formula: C21H27N5O6S. Mole weight: 477.54.
CJC-1295
CJC-1295 is a growth hormone releasing hormone (GHRH) analog that can be used for growth hormone (GH) deficiency as a long-acting agent. Synonyms: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2; L-tyrosyl-D-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-glutaminyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-leucyl-L-seryl-L-argininamide. CAS No. 863288-34-0. Molecular formula: C152H252N44O42. Mole weight: 3367.9.
CJC1295 With DAC
CJC1295 is a synthetic analogue of growth hormone-releasing hormone. Uses: Cjc1295 with dac, also known as dac:grf (1-29), is a synthetic modification of the growth hormone releasing hormone (ghrh) peptide. this peptide is designed to stimulate the pituitary gland to produce and release growth hormone (gh) in a more sustained manner than natural ghrh. it contains a series of amino acids designed to mimic the effects of natural ghrh in the body. the addition of dac (drug. Grade: 98%. CAS No. 446262-90-4. Molecular formula: C165H269N47O46. Mole weight: 3647.19.
C-Jun-amino-terminal kinase-interacting protein 2 (683-692)
C-Jun-amino-terminal kinase-interacting protein 2 (683-692) is a peptide fragment of C-Jun-amino-terminal kinase-interacting protein 2. C-Jun N-terminal kinases (JNKs) are a family of protein kinases that play a central role in stress signaling pathways implicated in gene expression, neuronal plasticity, regeneration, cell death, and regulation of cellular senescence. It can be used in Ovarian carcinoma research.
c-JUN peptide is a JNK/c-Jun interaction inhibitor. Synonyms: (2S)-4-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]hexanoyl]amino]-4-oxobutanoic acid. Grade: >98%. CAS No. 610273-01-3. Molecular formula: C121H210N36O34S. Mole weight: 2745.24.
CK0106023
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons. Synonyms: CK 0106023; CK-0106023; N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide. CAS No. 336115-72-1. Molecular formula: C30H32BrClN4O2. Mole weight: 595.97.
CK-119
CK-119, a dihydropyridazino-pyridazine compound, is a potent IL-1 blocker to inhibit cell growth of fibroblast-like corneal and conjunctival cells mainly through the inhibition of DNA and RNA syntheses but not protein synthesis. Synonyms: diethyl 6-[(4-chlorophenyl)methyl]-1,4-dimethyl-5-oxopyridazino[4,5-c]pyridazine-3,4-dicarboxylate; CK-119; CK119; CK 119; UNII-AL53N923EI; GC-6119; GC 6119; GC6119. Grade: >98%. CAS No. 197917-10-5. Molecular formula: C21H23ClN4O5. Mole weight: 446.88.
CK156
CK156, a chemical probe, is a highly selective death-associated protein kinase (DAPK) inhibitor with IC50s of 182 nM,34 μM, and 39 μM in the DRAK1 NanoBRET assay for DRAK1, CK2a1, and CK2a2, respectively. CK156 can be used for the research of autoimmune and inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2910938-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149006.
CK 17
CK 17 is a interleukin-1 antagonist. It can suppress fibroblast proliferation. Synonyms: CK 17; CK17; CK-17; 5-Bromotetrahydro-5-methyl-3-phenyl-2-(phenylimino)-4H-1,3-thiazin-4-one. Grade: 98%. CAS No. 86727-00-6. Molecular formula: C17H15BrN2OS. Mole weight: 375.29.
CK1-IN-1
CK1-IN-1 is an inhibitor of casein kinase 1 (CK1) with IC50 of 15 nM, 16 nM and 73 nM for CK1δ, CK1ε and p38α MAPK, respectively. Synonyms: PUN51207; Compound 1C. CAS No. 1784751-20-7. Molecular formula: C24H15F2N3. Mole weight: 383.39.
CK1-IN-2
CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1383376-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153866.
CK1-IN-3
CK1-IN-3 is a casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases. Synonyms: N-(6-Methoxybenzo[d]thiazol-2-yl)-2-(2-methoxyphenyl)acetamide; N-[(2E)-6-methoxy-1,3-benzothiazol-2(3H)-ylidene]-2-(2-methoxyphenyl)acetamide. CAS No. 349438-74-0. Molecular formula: C17H16N2O3S. Mole weight: 328.39.
CK-2130
CK-2130 is a bio-active imidazolone developed to treat congestive heart failure. It inhibited human platelet aggregation produced by adenosine diphosphate and sodium arachidonate. Uses: Ck-2130 is used to treat congestive heart failure. Synonyms: CK 2130; CK-2130; CK2130. 4-Ethyl-1,3-dihydro-5-[4-[(2-methyl-1H-imidazol)-1-yl]benzoyl]-2H-imidazol-2-one; CK2130; 4-Ethyl-5-[4-(2-methylimidazol-1-yl)benzoyl]-1,3-dihydroimidazol-2-one. Grade: >98 %. CAS No. 101184-07-0. Molecular formula: C16H16N4O2. Mole weight: 296.33.
CK-2289
CK-2289 is an type III cyclic 3'5'-adenosine monophosphate phosphodiesterase inhibitor. It may be used in the treatment of congestive heart failure. Uses: Ck-2289 may be used in the treatment of congestive heart failure. Synonyms: CK 2289; CK-2289; CK2289. 4-[4-(1H-Imidazol-1-yl)benzoyl]-5-ethyl-1H-imidazol-2(3H)-one; 4-Ethyl-5-[4-(1H-imidazol-1-yl)benzoyl]-1H-imidazol-2(3H)-one; 2H-Imidazol-2-one,4-ethyl-1,3-dihydro-5-[4-(1H-imidazol-1-yl)benzoyl]-; 4-Ethyl-1,3-dihydro-5-[4-(1H-imidazol-1-yl)benzoyl]-2H-imidazol-2-one. Grade: >98 %. CAS No. 101183-99-7. Molecular formula: C15H14N4O2. Mole weight: 282.30.
CK2/ERK8-IN-1
CK2/ERK8-IN-1 is a dual inhibitor of casein kinase 2 (CK2) and ERK8. It also binds to Pim-1, HIPK2, and DYRK1A. CK2/ERK8-IN-1 induces apoptosis in Jurkat cells when used at concentrations ranging from 10 to 50 μM. Synonyms: TMCB; 4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzimidazole-1-acetic acid. Grade: ≥99%. CAS No. 1085822-09-8. Molecular formula: C11H9Br4N3O2. Mole weight: 534.82.
CK2 inhibitor 10
CK2 inhibitor 10 is a potent and ATP-competitive inhibitor of protein kinase (CK2; IC50 values of 32 nM and 46 nM for CK2α and CK2α' respectively). Compound 10 dose-dependently inhibits the kinases. It exhibits potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116, and breast cancer cells MCF-7. Synonyms: CK2-IN-3b; 4-(2-(4-methoxybenzamido)thiazol-5-yl)benzoic acid. Grade: 99%. CAS No. 1361229-76-6. Molecular formula: C18H14N2O4S. Mole weight: 354.38.
CK2 inhibitor 2
CK2 inhibitor 2 is a potent, selective and orally active CK2 inhibitor with favorable antiproliferative and antitumor activities. It has high selectivity for Clk2 (IC50 = 32.69 nM)/CK2 (IC50 = 0.66 nM). Synonyms: 5-(3-chlorophenylamino)-N-(2-hydroxyethyl)benzo[c][2,6]naphthyridine-8-carboxamide; Benzo[c][2,6]naphthyridine-8-carboxamide, 5-[(3-chlorophenyl)amino]-N-(2-hydroxyethyl)-. Grade: ≥98%. CAS No. 2641079-92-5. Molecular formula: C21H17ClN4O2. Mole weight: 392.84.