A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Robusta originated in central and western sub-Saharan Africa. It is the second most popular coffee in the world, making up 40% of the worlds coffee production. Robusta coffee benefits are increases energy and improves mental health and well-being, contains antioxidants, which are beneficial for skin and hair. It has a diuretic effect and can help with nausea. It is a high-caffeine, creamy, somewhat bitter version of the coffee full of benefits. The main constituents of coffee are caffeine, tannin, fixed oil, carbohydrates, and proteins. It contains 2-3% caffeine, 3-5% tannins, 13% proteins, and 10-15% fixed oils. In the seeds, caffeine is present as a salt of chlorogenic acid (CGA). Uses: Flavor. Group: Plant Extracts. INCI Names: Coffea Robusta (Coffee) Seed Extract. Grades: INDUSTRIAL GRADE. CAS No. 97593-13-0. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CF-0202. Olfactive Profile: Peanuty, roasted, smokey, bitter. EC No: 307-315-5. Origin: Indonesia.
New Jersey
Coffee Robusta Oil - CO2
Van Aroma is one of the leading producers of Coffee Robusta Oil - CO2. Van Aroma is one of the biggest exporters in Indonesia. We produce and export Coffee Robusta Oil - CO2 from sustainable and fully traceable sources. Uses: Aromatherapy, Skin Care, Pharmaceutical. Group: Plant Extracts. INCI Names: Coffea Robusta (Coffee) Seed Oil. Grades: INDUSTRIAL GRADE. CAS No. 97593-13-0. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CF-002. Olfactive Profile: Peanuty, roasted, smokey, bitter. EC No: 307-315-3. Origin: Indonesia.
New Jersey
Coffee Seed Extract
Coffee (Coffea arabica) seed extract, dissolved in water, glycerin, and propanediol; contains proteins, polysaccharides, methylxanthines, sucrose, lipids, caffeine, trigonelline, and minerals. Product ID: CI-SC-0662. Alfa Chemistry - ISO 9001:32057 Certified.
COG 133 is a fragment of Apolipoprotein E (APOE) peptide. COG 133 competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 is also a nAChR antagonist with an IC50 of 445 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 514200-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1050.
COG 133
COG 1333 is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Synonyms: COG133; COG-133; Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu. Grade: 98%. CAS No. 514200-66-9. Molecular formula: C97H181N37O19. Mole weight: 2169.73.
COG 133 acetate
COG 133 acetate is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Synonyms: Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.CH3CO2H; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide acetic acid; L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, acetate (1:1). Grade: ≥95%. CAS No. 2763583-75-9. Molecular formula: C99H185N37O21. Mole weight: 2229.76.
COG 133 TFA
COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC50 of 445 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2828432-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1050A.
COG 133 TFA
COG133 is a peptide fragment of ApoE that corresponds to residues 133-149 of the ApoE LDL receptor-binding domain and an antagonist of α7 nicotinic acetylcholine receptors (nAChRs; IC50 = 720 nM). It suppresses TNF-α and nitric oxide (NO) release in BV-2 microglia when used at concentrations ranging from 10 to 50 μM. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, 2,2,2-trifluoroacetate (1:1); Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.TFA; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide trifluoroacetic acid. Grade: 98%. CAS No. 2828432-37-5. Molecular formula: C99H182F3N37O21. Mole weight: 2283.78.
COG1410
COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 878009-24-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2136.
COG-1410
COG-1410 is an apolipoprotein E (apoE) peptide mimetic containing the amino acid sequence of the receptor-binding domain apoE. CAS No. 878009-24-6. Molecular formula: C64H121N21O14. Mole weight: 1408.8.
COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1534358-79-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114304.
COH000
COH000 is an allosteric and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme). COH000 targets a cryptic pocket distinct from the active site that is completely buried in all previous SUMO E1 structures. Synonyms: (1R,4S)-Dimethyl 1-((R)-1-(phenylamino)-2-(p-tolyl)ethyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate. CAS No. 1534358-79-6. Molecular formula: C25H25NO5. Mole weight: 419.47.
COH29
COH29 (RNR Inhibitor COH29) is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50s of 16 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RNR Inhibitor COH29. CAS No. 1190932-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19931.
COH-29 is a potent inhibitor of ribonucleotide reductase (RNR). It inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM. Synonyms: RNR Inhibitor COH29. CAS No. 1190932-38-7. Molecular formula: C22H16N2O5S. Mole weight: 420.44.
COH34
COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0.37 nM. COH34 binds to the catalytic domain of PARG (Kd=0.547 μM), thereby prolonging PARylation at DNA lesions and trapping DNA repair factors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 906439-72-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-128760.
COH34
COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor that binds to the catalytic domain of PARG, thereby prolonging PARylation at DNA lesions and trapping DNA repair factors. Synonyms: COH-34; COH 34. Grade: >98%. CAS No. 906439-72-3. Molecular formula: C18H15NOS. Mole weight: 293.38.
Cohumulone
Cohumulone is one of three major analogues of hop a-acids, the others being adhumulone and humulone. Synonyms: Cohumulone; 511-25-1; 142628-20-4; 2Y34G4NIC8; (+/-)-cohumulone; 3,5,6-trihydroxy-4,6-bis(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one; 5-(alpha,beta-Dibromophenethyl)-5-methylhydantoin; UNII-2Y34G4NIC8; 2,5-Cyclohexadien-1-one, 3,4,5-trihydroxy-2-isobutyryl-4,6-bis(3-methyl-2-butenyl)-; COHUMULONE, (-)-; SCHEMBL317724; SCHEMBL13629034; GTPL12422; DTXSID20931549; CHEBI:175443; DRSITEVYZGOOQG-UHFFFAOYSA-N; DTXSID701318500; Q2981886; Q27893896; (-)-3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-2,5-CYCLOHEXADIEN-1-ONE; 2,5-CYCLOHEXADIEN-1-ONE, 3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-, (-)-; 3,4,5-Trihydroxy-2,4-bis(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-2,5-cyclohexadien-1-one, 9CI; 3,5,6-TRIHYDROXY-4,6-BIS(3-METHYLBUT-2-EN-1-YL)-2-(2-METHYLPROPANOYL)CYCLOHEXA-2,4-DIEN-1-ONE. Grade: > 95%. CAS No. 511-25-1. Molecular formula: C20H28O5. Mole weight: 348.44.
Co(III) protoporphyrin IX chloride
Co(III) protoporphyrin IX chloride (Protoporphyrin IX cobaltic chloride) is an inducer of HO-1. Co(III) protoporphyrin IX chloride has activities such as anti-inflammation and antibacterial properties. Co(III) protoporphyrin IX chloride can also be used in the research of ischemia-reperfusion injury models[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Protoporphyrin IX cobaltic chloride; CoPPIX-Cl. CAS No. 102601-60-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W250116.
Coiled-coil and C2 domain-containing protein 2A isoform a (1275-1287)
Coiled-coil and C2 domain-containing protein 2A isoform a (1275-1287) is a fragment of Coiled-coil and C2 domain-containing protein 2A isoform a. Coiled-coil and C2 domain-containing protein 2A is a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation.
Coiled-coil domain-containing protein 110 (196-204)
A peptide fragment of Coiled-coil domain-containing protein 110. Coiled-coil domain containing 110 (CCDC110, KM-HN-1) is a protein containing C-terminal coiled-coil domain (CCD) which was previously discovered as a member of the human cancer/testis antigen (CTA). Synonyms: Cancer/testis antigen 52 (196-204); Cancer/testis antigen KM-HN-1 (196-204).
Coiled-coil domain-containing protein 110 (499-508)
A peptide fragment of Coiled-coil domain-containing protein 110. Coiled-coil domain containing 110 (CCDC110, KM-HN-1) is a protein containing C-terminal coiled-coil domain (CCD) which was previously discovered as a member of the human cancer/testis antigen (CTA). Synonyms: Cancer/testis antigen 52 (499-508); Cancer/testis antigen KM-HN-1 (499-508).
Coiled-coil domain-containing protein 110 (770-778)
A peptide fragment of Coiled-coil domain-containing protein 110. Coiled-coil domain containing 110 (CCDC110, KM-HN-1) is a protein containing C-terminal coiled-coil domain (CCD) which was previously discovered as a member of the human cancer/testis antigen (CTA). Synonyms: Cancer/testis antigen 52 (770-778); Cancer/testis antigen KM-HN-1 (770-778).
Co in-situ doped Ti3AlC2 MAX
Co in-situ doped Ti3AlC2 MAX. CAS No. 196506-01-1. Purity: 0.99.
Coixol
Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) is a potent and orally active anti-inflammatory agent. Coixol decreases the iNOS protein expression. Coixol inhibits the production of TNF-α, IL-6, and IL-1β. Coixol improves glucose tolerance and plasma insulin. Coixol decreases the blood glucose level[1][2][3]. Uses: Scientific research. Category: Natural products. Alternative Names: 6-Methoxy-2-benzoxazolinone; 6-MBOA. CAS No. 532-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0936.
Coixol (Standard)
Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) is a potent and orally active anti-inflammatory agent. Coixol decreases the iNOS protein expression. Coixol inhibits the production of TNF-α, IL-6, and IL-1β. Coixol improves glucose tolerance and plasma insulin. Coixol decreases the blood glucose level[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methoxy-2-benzoxazolinone (Standard); 6-MBOA (Standard). CAS No. 532-91-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0936R.
Coix Seed Powder
Coix Seed Powder. Applications: Pharmaceutical, functional food, water-soluble beverages, health products. Group: Others. Appearance: Off-white Powder. Source: Seed spheroidal or sem-spherical, obtuse-round at one end and somewhat flat at the other, 0. 5-0. 7 cm in length. Surface smooth, milky white in colour, occasionally remained with brownish testa, A deeply and widely grooved, concavely basilar and spotted hilum appearing at the flat end. Hard in texture. Fracture section appearing white and farnaceous. Coix Seed Powder; Semen Coicis. Cat No: EXTC-150.
Col003
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 328565-16-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124817.
Col003
Col003 is a potent and selective collagen-heat-shock protein 47 (Hsp47) interaction inhibitor with IC50 of 1.8 μM. Synonyms: 5-benzyl-2-hydroxy-3-nitro-benzaldehyde. Grade: 99%. CAS No. 328565-16-8. Molecular formula: C14H11NO4. Mole weight: 257.24.
COL1A1 Antibody [B17N21]
COL1A1,Collagen I alpha 1. Group: Antibodies. Alternative Names: Collagen I α 1. Pack Sizes: 20ul. Product ID: F1228. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
Colabomycin A
It is produced by the strain of Streptomyces griseoflavus. It has anti-gram-positive bacterial activity similar to Manumycin, and has the activity of inhibiting leukemic cell L1210. IC50 is 3.4 μg/mL. Synonyms: (2E,4E,6E,8E)-N-[(1beta,6beta)-5alpha-Hydroxy-5-[(1E,3E,5E,7E)-9-[(2-hydroxy-5-oxo-1-cyclopentene-1-yl)amino]-9-oxo-1,3,5,7-nonatetrenyl]-2-oxo-7-oxabicyclo[4.1.0]hepta-3-ene-3-yl]-2,4,6,8-decatetrenamide. CAS No. 117778-57-1. Molecular formula: C30H30N2O7. Mole weight: 530.57.
Colcemid
Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer and thrombopoietic agent.Source:Semi-synthetic from colchicine: Group: Biochemicals. Grades: Highly Purified. CAS No. 477-30-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H25NO5, Method for Determining. US Biological Life Sciences.
Worldwide
Colcemid
5mg Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C21H25NO5. CAS No. 477-30-5. Prepack ID 71672781-5mg. Molecular Weight 371.43. See USA prepack pricing.
Colcemide
Colcemide. Group: Biochemicals. Alternative Names: N-Deacetyl-N-methylcolchicine ; Demecolcine. Grades: Highly Purified. CAS No. 477-30-5. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C21H25NO5. US Biological Life Sciences.
Worldwide
Colchiceine
A metabolite of Colchicine. Group: Biochemicals. Alternative Names: N-[(7S)-5,6,7,9-Tetrahydro-10-hydroxy-1,2,3,-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; O10-Demethylcolchicine; NSC 33411. Grades: Highly Purified. CAS No. 477-27-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Colchicine
Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research[1][2][3][4][5]. Uses: Scientific research. Category: Induced disease models products. CAS No. 64-86-8. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-16569.
Colchicine
Colchicine is a microtubule polymerization inhibitor with an IC50 of 3 nM. Group: Inhibitors. Alternative Names: Colchineos, Colchisol, Colcin,NSC 757. CAS No. 64-86-8. Pack Sizes: 1g. Product ID: S2284. Formula: C22H25NO6. Smiles: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Colchicine
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals. Formula: C22H25NO6. CAS No. 64-86-8. Prepack ID 22115544-1g. Molecular Weight 399.44. See USA prepack pricing.
Colchicine
Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). It inhibits the growth of MCF-7 human breast carcinoma cells and has anti-inflammatory activity. Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Synonyms: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; (-)-Colchicine; Colchineos; Colchisol; Colcin; Colsaloid; Condylon; NSC 757. Grade: >98%. CAS No. 64-86-8. Molecular formula: C22H25NO6. Mole weight: 399.44.
Colchicine-[13C,d3]
Colchicine-[13C,d3], is the labelled analogue of Colchicine. Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Synonyms: Colchicine 13C D3. Grade: > 95%. Molecular formula: C21[13C]H22D3NO6. Mole weight: 403.44.