A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Combretastatin A4 phosphate disodium salt. Alternative Names: Fosbretabulin disodium salt. CAS No. 168555-66-6. Purity: 98+%. Product ID: ACM168555666-1. Molecular formula: C18H19Na2O8P. Mole weight: 440.30. Alfa Chemistry - ISO 9001:32057 Certified.
Combretastatin A-4 Phosphate, Disodium Salt (CA 4P)
Phosphorylated, Combretastatin a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Indu. Group: Biochemicals. Alternative Names: CA 4P. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Inducer. Group: Biochemicals. Alternative Names: (Z) -2-Methoxy-5-[2- (3, 4, 5-trimethoxyphenyl) ethenyl]phenol, 3,4,5-Trimethoxy-3-hydroxy-4-methoxy-(Z)-stilbene, CS-A4. Grades: Highly Purified. CAS No. 117048-59-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Comekibart
HY-P990910 is an IL4R-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MG-K10. CAS No. 2833673-47-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990910.
Comenic acid
Comenic acid. Group: Biochemicals. Alternative Names: 5-Hydroxy-4-oxo-4H-pyran-2-carboxylic acid. Grades: Highly Purified. CAS No. 499-78-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C6H4O5. US Biological Life Sciences.
Worldwide
CO-methylating acetyl-CoA synthase
Contains nickel, copper and iron-sulfur clusters. Involved, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin), in the synthesis of acetyl-CoA from CO2 and H2. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.169. CAS No. 176591-19-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2109; CO-methylating acetyl-CoA synthase; EC 2.3.1.169; 176591-19-8. Cat No: EXWM-2109.
Comfrey Extract
Comfrey (Symphytum officinale) leaf extract, 20% in water-glycerin, softening, soothing, and anti-irritant. CAS No. 84696-05-9. Product ID: CI-SC-0843. Alfa Chemistry - ISO 9001:32057 Certified.
Comin's reagent
Comin's reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 145100-51-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Commendamide
Commendamide is a natural bacterial product which was discovered in a screen for commensal bacteria effector genes (Cbegs). Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. Synonyms: N-acyl-3-hydroxypalmitoyl-Glycine; 2-(3-hydroxyhexadecanoylamino)acetic acid. Grade: ≥95%. CAS No. 193825-78-4. Molecular formula: C18H35NO4. Mole weight: 329.5.
Commodity Chemicals
Common Chitosan
Common Chitosan.
Common Fenugreek Seed Extract
Common Fenugreek Seed Extract. Product ID: CI-NAT-0013. Alfa Chemistry - ISO 9001:32057 Certified.
Compd with cholesteryl sulfate
Compd with cholesteryl sulfate. CAS No. 120895-52-5. Product ID: ACM120895525. Alfa Chemistry - ISO 9001:32057 Certified.
Compel LFRT
Compel LFRT.
Competence-stimulating peptide
Competence-stimulating peptide is a competence-stimulating peptide. Competence-stimulating peptide activates the Com-dependent quorum sensing system of S. mutans. Competence-stimulating peptide restores bacteriocin production[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 438620-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11175.
Competence-Stimulating Peptide-12261
Competence-Stimulating Peptide-12261, is a fragment of Competence-Stimulating Peptide (CSP) composed of 16 amino acids. CSP is a quorum sensing molecule that inhibits the formation of germ tubes (GT). Synonyms: Glu-Ile-Arg-Gln-Thr-His-Asn-Ile-Phe-Phe-Asn-Phe-Phe-Lys-Arg-Arg; CSP-12261. Grade: ≥95%. CAS No. 1235882-91-3. Molecular formula: C100H149N31O23. Mole weight: 2153.45.
Competence-Stimulating Peptide-2 (CSP-2)
Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae, with an EC50 of 50.7 nM for its compatible receptor ComD2. Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1174553-84-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2522.
Complanatoside A
Complanatoside A. Group: Biochemicals. Alternative Names: Myricetin 3,4?-diglucoside. Grades: Plant Grade. CAS No. 146501-37-3. Pack Sizes: 10mg. Molecular Formula: C27H30O18, Molecular Weight: 642.515999999999. US Biological Life Sciences.
Worldwide
Complanatuside
Complanatuside. Group: Biochemicals. Grades: Plant Grade. CAS No. 116183-66-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Complanatuside 6''-malonate
Complanatuside 6''-malonate. Group: Biochemicals. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Complement C1s-IN-1
Complement C1s-IN-1 is a potent, selective, orally active and cross the blood-brain barrier C1s inhibitor with an IC50 value of 36 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033831-40-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-149278.
Complement C5-IN-1
Compound C5-IN-1 (Compound 7) is a selective allosteric inhibitor of complement component protein C5. Compound C5-IN-1 prevents C5 from being cleaved by C5 convertase, inhibits the cleavage of C5 into C5a and C5b, and thus blocks the formation of membrane attack complex (MAC). Compound C5-IN-1 has an IC50 of 0.77 μM and 5 nM in 50% human whole blood and 2% human serum to block MAC deposition induced by zymosan, respectively. Compound C5-IN-1 can be used to study diseases related to complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2365402-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128342.
complement factor D
A component of the alternative pathway of complement activation. This reaction is analogous to the activation of complement component C2 by complement subcomponent C1s. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Enzyme Commission Number: EC 3.4.21.46. CAS No. 37213-56-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4139; complement factor D; EC 3.4.21.46; 37213-56-2; C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Cat No: EXWM-4139.
Complement factor D-IN-2
Complement factor D-IN-2, a complement factor D inhibitor, is used in the study of autoimmune diseases. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. (Extracted from patent WO2015130838A1, compound 190). Synonyms: 2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-; JYN42346; JYN 42346; JYN-42346. Grade: ≥95%. CAS No. 1903742-34-6. Molecular formula: C27H24BrN7O3. Mole weight: 574.43.
complement factor I
Cleavage of complement subcomponent C3b requires its binding to cofactor factor H or complement receptor CR1; cleavage of iC3b requires complement receptor CR1; cleavage of C4b requires C4b-binding protein. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: complement component C3b inactivator; C3b inactivator; C3b/C4b inactivator; C3bINA; complement C3b/C4b inactivator; complement C4b inactivator; conglutinogen-activating factor C; complement C3b inactivator; factor I; complement C4bi. Enzyme Commission Number: EC 3.4.21.45. CAS No. 80295-66-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4138; complement factor I; EC 3.4.21.45; 80295-66-5; complement component C3b inactivator; C3b inactivator; C3b/C4b inactivator; C3bINA; complement C3b/C4b inactivator; complement C4b inactivator; conglutinogen-activating factor C; complement C3b inactivator; factor I; complement C4bi. Cat No: EXWM-4138.
complement subcomponent C1r
Activated from proenzyme C1r in plasma during activation of the complement system by the "classical" route. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: activated complement C1r; C1r esterase; activated complement C1r. Enzyme Commission Number: EC 3.4.21.41. CAS No. 80295-69-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4135; complement subcomponent C1r; EC 3.4.21.41; 80295-69-8; activated complement C1r; C1r esterase; activated complement C1r. Cat No: EXWM-4135.
complement subcomponent C1s
Activated from proenzyme C1s in plasma by complement subcomponent C1r. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C1 esterase; activated complement C1s; complement C1r. Enzyme Commission Number: EC 3.4.21.42. CAS No. 80295-70-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4136; complement subcomponent C1s; EC 3.4.21.42; 80295-70-1; C1 esterase; activated complement C1s; complement C1r. Cat No: EXWM-4136.
Complete Freund's adjuvant (CFA)
Complete Freund's adjuvant (CFA) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund to enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA) stimulates a strong and durable immune response and can be used to induce persistent inflammatory pain models in mice, experimental autoimmune myocarditis (EAM) models, and more. Incomplete Freund's adjuvant (IFA) (HY-153808A) is another type of Freund's Adjuvant that stimulates a weaker immune response[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 9007-81-2. Pack Sizes: 10 mL; 10 mL * 2; 10 mL * 5. Product ID: HY-153808.
Complete Freund's adjuvant (CFA, 1 mg/ml)
Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more[1][2][3]. Uses: Scientific research. Category: Induced disease models products. CAS No. 9007-81-2. Pack Sizes: 10 mL. Product ID: HY-153808B.
Completely Denatured Alcohol CDA 12A 275 TOTE
275 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A 330 TOTE
330 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A BULK
Tanker volume. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A DRUM
55 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON
1 gallon of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON CASE
4 gallons of product (4 bottles). Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A PALE
5 gallons of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Complex Antigen Liposome
This liposome contains a fusion protein prepared from MAGE-1 and Hsp70, and staphylococcal enterotoxin A. It is only for research purposes. Group: Liposomal vaccine or adjuvant.
Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15%
Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15%. Synonyms: Active hexose correlated compound; Complex of 1-[3-(α-D-Glucopyranosyloxy)-2-furanyl]-ethanone 85% and 1-[3-(4-O-α-D-Glucopyranosyl-α-D-glucopyranosyloxy)-2-furanyl]-ethanone 15%. Grade: ≥97%. Molecular formula: C12H16O8.C18H26O13. Mole weight: 450.39/288.25.
Compound 10
Compound 10 is a tool compound targeting the NFAT:AP-1 transcriptional complex on DNA. Synonyms: 2-(5-(1H-Benzo[d]imidazol-2-yl)pyridin-2-ylthio)-N-(3-acetamidophenyl)acetamide. Grade: 99%. CAS No. 841210-82-0. Molecular formula: C22H19N5O2S. Mole weight: 417.48.
Compound 120
Compound 120 is a partially deuterated analogue of Atazanavir, which is an oral HIV protease inhibitor. Compound 120 increases half life by approximately 50% in comparison with Atazanavir. Synonyms: Atazanavir-d15 sulfate. Grade: 99%. Molecular formula: C38H37D15N6O7.H2O4S. Mole weight: 818.03.
Compound 1T-0216
Compound 1T-0216 is a blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: 1-(2-{[(2-methylbenzoyl)oxy]imino}cyclohexyl)-2,4-dinitrobenzene; [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 2-methylbenzoate. CAS No. 383147-88-4. Molecular formula: C20H19N3O6. Mole weight: 397.39.
Compound 1T-0219 (SC)
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction which reduces the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 4-methoxybenzoate; N-[2-(2,4-dinitrophenyl)cyclohexyliden]-N-[(4-methoxybenzoyl)oxy]amine; ZINC4085554. CAS No. 383147-92-0. Molecular formula: C20H19N3O7. Mole weight: 413.37.
Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interaction with an affinity of 126 nm. Synonyms: 4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-N-(3-((dimethylamino)methyl)phenyl)-2-methoxyaniline hydrochloride; Benzenemethanamine, 3-[[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethyl-, hydrochloride (1:1); 3-[[4-(2,3-Dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethylbenzenemethanamine hydrochloride; [4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-2-methoxyphenyl][3-[(dimethylamino)methyl]phenyl]amine hydrochloride. Grade: ≥95%. CAS No. 2760889-75-4. Molecular formula: C24H26N2O3.HCl. Mole weight: 426.94.
Compound 34
Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06nM). Group: Biochemicals. Alternative Names: (2S,3R)-3-(3,4-Difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-2-oxo-5-phenyl-2,3-1H-benzodiazepin-3-yl)butyramide. Grades: Highly Purified. CAS No. 564462-36-8. Pack Sizes: 200ug, 1mg. Molecular Formula: C31H24F3N3O3. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401. Group: Biochemicals. Grades: Purified. CAS No. 168425-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401, a pyrimido-isoquinolinone compound, is a selective and cell-permeable inhibitor that has an reversible function on DNA-dependent protein kinase (DNA-PK). It is also a mammalian target of rapamycin (mTOR) with little affinity for 43 other com. Synonyms: 2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-oneCompound 401; Compound-401; Compound401; 168425-64-72-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-oneCHEMBL1792422-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-oneSCHEMBL10092321CTK4D2994S-7713; S 7713; S77132-(morpholin-4-yl)pyrimido[2,1-a]iso. Grade: >99 %. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Mole weight: 281.31.
Compound 43 TAO Kinase Inhibitor
Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grade: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47.
Compound 48/80
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Poly-p-methoxyphenethylmethylamine. CAS No. 94724-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115768.
Compound 48/80 hydrochloride
Compound 48/80 is a condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde that causes histamine degranulation from mast cells. Compound 48/80 also inhibits human platelet aggregation through suppression of calmodulin (CaM) (IC50 = 0.41 μg/ml for CaM-dependent Ca2+-transporter ATPase activity) and phospholipase C. Synonyms: 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-benzeneethanamine trihydrochloride. Grade: ≥95%. CAS No. 848035-21-2. Molecular formula: C32H45N3O3·3HCl. Mole weight: 629.1.
Compound 48/80 trihydrochloride
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C48/80 trihydrochloride. CAS No. 848035-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130592.
Compound 56
Compound 56 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM). It has been used to inhibit EGFR activity in pancreatic cancer cell lines and it can induce the differentiation of rat mesenchymal stem cells. Synonyms: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine. Grade: ≥95%. CAS No. 171745-13-4. Molecular formula: C18H18BrN3O2. Mole weight: 388.3.
Compound E
Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grade: 98%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5.
Compound E
Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity. Group: Biochemicals. Alternative Names: (2S)-2-(amino)-N-propanamide. Grades: Highly Purified. CAS No. 209986-17-4. Pack Sizes: 250ug, 1mg, 5mg. Molecular Formula: C27H24F2N4O3. US Biological Life Sciences.
Worldwide
Compound E
Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: γ-Secretase-IN-1. CAS No. 209986-17-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14176.
Compound O-Ring
Compound O-Ring.
Compound W
Compound W. Group: Biochemicals. Grades: Purified. CAS No. 173550-33-9. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Compound W
Compound W, also called 3,5-bis(4-Nitrophenoxy)benzoic acid, a 3,3'-diiodothyronine sulfate cross-reactive substance, is an inhibitor of γ-secretase which causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). Synonyms: 3,5-bis(4-Nitrophenoxy)benzoic acid; 173550-33-9; gamma-Secretase Modulator, CW; ACMC-1CUIP; SCHEMBL264541; CHEMBL1553155; CTK8B1007; JOSXKPZXMVHRKU-UHFFFAOYSA-; DTXSID10587892; JOSXKPZXMVHRKU-UHFFFAOYSA-N; HMS3269J17; ZINC2576957; ANW-22664; MFCD02093450; AKOS015833412; 3,5-bis (4-nitrophenoxy) benzoic acid; NCGC00167814-01; AJ-42568; AK-63150; EN002659; OR182673; KB-234083; TR-007681; B2120; Compound W|CW|3,5-Bis(4-nitrophenoxy)benzoic acid; BRD-K98143539-001-01-4; I14-62910. Grade: >98.0%(T)(HPLC). CAS No. 173550-33-9. Molecular formula: C19H12N2O8. Mole weight: 396.31.
Compound W (CW, 3,5-Bis(4-nitrophenoxy)benzoic acid)
Compound W is a y-secretase inhibitor that has been shown to lower the levels of secreted Ab42 and Nb25. Group: Biochemicals. Grades: Highly Purified. CAS No. 173550-33-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
Worldwide
Compound Y-1
Compound Y-1 is a neuraminidase inhibitor with IC50 of 0.21 μM. Compound Y-1 exhibits activity against H1N1 influenza virus. Synonyms: Neuraminidase-IN-1; Y-1. Grade: 99.22%. CAS No. 2379438-80-7. Molecular formula: C14H11N3O6. Mole weight: 317.25.
Compstatin
Compstatinis, a 13-residue cyclic peptide, is a potent inhibitor of the complement system (IC50= 12 μM) and binds to complement component C3. Synonyms: H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2; L-isoleucyl-L-cysteinyl-L-valyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-tryptophyl-glycyl-L-histidyl-L-histidyl-L-arginyl-L-cysteinyl-L-threoninamide (2->12)-disulfide; 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10,13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33-decaoxo-28,31-di(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid. Grade: 98%. CAS No. 206645-99-0. Molecular formula: C66H99N23O17S2. Mole weight: 1550.77.
Compstatin
Compstatin, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin inhibits only the activation of primates complement system. Compstatin exhibits IC50 values of 63 μM and 12 μM for classical and alterative complement pathway, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 206645-99-0. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1036.
Compstatin
Compstatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 206645-99-0. Pack Sizes: 1mg. Molecular Formula: C66H99N23O17S2, Molecular Weight: 1550.77. US Biological Life Sciences.
Worldwide
Compstatin control peptide
Compstatin control peptide is a negative control of Compstatin (HY-P1036). Compstatin is a potent complement system C3 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301544-78-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1398.
Compstatin control peptide
Compstatin control peptide. Group: Biochemicals. Grades: Purified. CAS No. 301544-78-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Compstatin control peptide
Compstatin control peptide is a kind of control peptide for compstatin. It is a complement inhibitor. Grade: >98%. CAS No. 301544-78-5. Molecular formula: C66H101N23O17. Mole weight: 1488.67.
COMU
COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grade: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27.
COMU®
Fast coupling efficiency, very low or non-existent tendencies for racemization. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (1-Cyano-2-ethoxy-2-Oxoethylidenaminooxy) Dimethylamino-morpholino-carbenium hexafluorophosphate. CAS No. 1075198-30-9. registered patent of Luxembourg Bio Technologies.
Luxembourg Bio Technologies
Conagenin
It is produced by the strain of Sreptomyces roseosporus M1696-AF3. It is a low molecular immune modulator. Synonyms: (S)-2-((2R,3S,4R)-2,4-dihydroxy-3-methylpentanamido)-3-hydroxy-2-methylpropanoic acid; N-(3,5-Dideoxy-3-methyl-D-xylonoyl)-2-methyl-L-serine; Conagenine. CAS No. 134381-30-9. Molecular formula: C10H19NO6. Mole weight: 249.26.
Conantokin-G
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Uses: Excitatory amino acid antagonists. Synonyms: Conotoxin GV; Conotoxin G V; Sleeper peptide; Conantokin G; Conotoxin G V; GEXXLQXNQX LIRXKSN; H-Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2. Grade: > 94.5 %. CAS No. 93438-65-4. Molecular formula: C88H138N26O44. Mole weight: 2264.23.
Conantokin-R
Conantokin-R is a potent and non-competitive NMDA receptor antagonist with IC50 value of 93 nM. It also has NR2 subunit selectivity. It inhibits inward currents evoked by NMDA in central nervous system neurons. It shows broad antiparkinsonian and anticonvulsant activity in vivo. Synonyms: Conantokin R; 202925-60-8; conantokin-RAKOS024457444; CID 90488802. Grade: >98%. CAS No. 202925-60-8. Molecular formula: C127H201N35O49S3. Mole weight: 3098.4.