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| Product | Description | |
|---|---|---|
| CP 339818 hydrochloride | CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574. |  |
| CP 339818 hydrochloride | CP 339818 hydrochloride is the hydrochloride salt form of CP 339818, a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, hydrochloride (1:1); 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, monohydrochloride; Cp 339818 monohydrochloride; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine hydrochloride; 1-Benzyl-N-pentylquinolin-4(1H)-imine hydrochloride; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 478341-55-8. Molecular formula: C21H24N2.HCl. Mole weight: 340.89. |  |
| CP 339818 hydrochloride | CP 339818 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 478341-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CP 346086 | CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48. | |
| CP-346086 | CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186390-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113955. | |
| CP-346086 dihydrate | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CP 346086 Dihydrate | CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CP-35587 | CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Synonyms: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43. | |
| CP 376395 | CP 376395 is a potent and selective CRF1 receptor antagonist. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP-376395; CP376395. Grade: >99 %. CAS No. 175140-00-8. Molecular formula: C21H30N2O. Mole weight: 326.5. | |
| CP-376395 HCl | CP-376395 HCl is a potent and selective CRF1 receptor antagonist with Ki values of 12 and >10000 nM for CRF1 and CRF2 receptors respectively. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP376395 HCl; CP 376395 HCl; 2-(Mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride; 3,6-Dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine hydrochloride. Grade: >98 %. CAS No. 1013933-37-3. Molecular formula: C21H31ClN2O. Mole weight: 362.94. | |
| CP 376395 hydrochloride | CP 376395 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1013933-37-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CP-376395 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-380736 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-394531 | CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grade: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14. | |
| CP-409092 | CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grade: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35. | |
| CP-409092 hydrochloride | CP-409092 hydrochloride is a GABAA receptor partial agonist for the treatment of general anxiety disorder (GAD). Synonyms: N-(4-((Methylamino)methyl)phenyl)-4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamide hydrochloride; 1H-Indole-3-carboxamide, 4,5,6,7-tetrahydro-N-[4-[(methylamino)methyl]phenyl]-4-oxo-, hydrochloride (1:1). Grade: ≥95%. CAS No. 225240-86-8. Molecular formula: C17H20ClN3O2. Mole weight: 333.81. | |
| CP 412065 | It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Synonyms: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53. | |
| CP 424174 | CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grade: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99. | |
| CP-424,174 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-432 | CP-432 is an EP4 prostaglandin agonist , potential useful for the treatment of glaucoma and ocular hypertension. Uses: An ep4 prostaglandin agonist. Synonyms: CP-432; CP 432; CP432; CP-734432; CP 734432; CP734432. 5-(3-((2S)-2-((3R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxo-1-pyrrolidinyl)propyl)-2-Thiophenecarboxylic acid. Grade: ≥95%. CAS No. 431990-08-8. Molecular formula: C23H26F3NO4S. Mole weight: 469.52. | |
| CP-456773 sodium | CP-456773, also known as MCC950 and CRID3, is a potent, orally bioavailable NLRP3 inflammasome inhibitor and inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production for the treatment of inflammatory diseases. Synonyms: sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide; MCC950; MCC 950; MCC-950; CP-45677; CP45677; CP 45677; CRID-3; CRID3; CRID 3; CP-456773 sodium salt; CP 456773 sodium salt; CP456773 sodium salt; Cytokine release inhibitory drug 3. CAS No. 256373-96-3. Molecular formula: C20H24N2NaO5S. Mole weight: 427.46. | |
| CP-456773 sodium salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-457677 | CP-457677, also called as TX006169, is a JNK inhibitor. Synonyms: 2-(4-fluorophenoxy)-N-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]pyridine-3-carboxamide; CP-457677; CP457677; CP 457677; UNII-5A83419M4U. Grade: >98%. CAS No. 214535-77-0. Molecular formula: C22H21FN2O3. Mole weight: 380.41. | |
| CP-457920 | CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued. Synonyms: N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920. Grade: >98%. CAS No. 220860-50-4. Molecular formula: C18H17N3O3. Mole weight: 323.35. | |
| CP 461 | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grade: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91. | |
| CP-461 free base | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grade: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45. | |
| CP 465022 | CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grade: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41. | |
| CP-465022 | CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663. | |
| CP 465022 hydrochloride | CP 465022 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199655-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CP-465022 hydrochloride | CP-465022 hydrochloride, a potent, selective and non-competitive AMPA receptor antagonist with anticonvulsant activity, is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. Synonyms: 3-(2-Chlorophenyl)-2-[(E)-2-{6-[(diethylamino)methyl]pyridin-2-yl}vinyl]-6-fluoroquinazolin-4(3H)-one hydrochloride (1:1); 4(3H)-Quinazolinone, 3-(2-chlorophenyl)-2-[(E)-2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-, hydrochloride (1:1); (E)-3-(2-chlorophenyl)-2-(2-(6-((diethylamino)methyl)pyridin-2-yl)vinyl)-6-fluoroquinazolin-4(3H)-one hydrochloride. CAS No. 1785666-59-2. Molecular formula: C26H25Cl2FN4O. Mole weight: 499.41. | |
| CP-465022 maleate | CP-465022 is a selective, non-competitive AMPA antagonist that displays potent anticonvulsant activity. Synonyms: CP-465022 (maleate); 199656-46-7; cp-465022 maleate; (Z)-but-2-enedioic acid; 3-(2-chlorophenyl)-2-[(E)-2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-392,110 (maleate); 3-(2-chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone-(2Z)-2-butenedioate; SCHEMBL8301393; CP465022(2Z)-2-butenedioate; ZHA65646; HY-18663A; AKOS037643494; CP 465022 (2Z)-2-butenedioate; AS-16611; CS-0013530. CAS No. 199656-46-7. Molecular formula: C26H24ClFN4O·C4H4O4. Mole weight: 579. | |
| CP 46665 | CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grade: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82. | |
| CP466722 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-466722 | CP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells. Synonyms: CP-466722; CP 466722; CP466722. Grade: >98%. CAS No. 1080622-86-1. Molecular formula: C17H15N7O2. Mole weight: 349.35. | |
| CP-467688 | CP-467688 is a microsomal triglyceride transfer protein inhibitor used in atherosclerosis therapy. Synonyms: methyl N-[2-[6-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]carbamate; hydrochloride; 909576-25-6 (CP-467688); CP 467688; CP467688; 208590-81-2 (CP-467688 free base). Grade: >98%. CAS No. 208590-81-2. Molecular formula: C27H27ClF3N3O3. Mole weight: 533.97. | |
| CP 471474 | CP 471474 a broad spectrum Matrix Metalloprotease inhibitor with sub-nanomolar affinity for MMP-2 and 13 among MMPs (IC50: 1170, 0.7, 16, 13, 0.9 for MMP-1, MMP-2, MMP-3, MMP-9, and MMP-13 respectively). Synonyms: CP-471474; CP 471474; CP471474; UNII-96U47H947L; 2-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxy-2-methylpropanamide; CP 471474; CP-471474; 210755-45-6; CHEMBL323612. Grade: >97 %. CAS No. 210755-45-6. Molecular formula: C16H17FN2O5S. Mole weight: 368.38. | |
| CP-471474 | A broad spectrum inhibitor of matrix metalloproteinases that attenuates early left ventricular dilation after experimental myocardial infarction in mice. Studies show that it also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models. Group: Biochemicals. Alternative Names: 2-[[[4- (4-Fluorophenoxy) phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide; CP 471474. Grades: Highly Purified. CAS No. 210755-45-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CP-471474 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-472555 | CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-472555; CP 472555; CP472555; UNII-6T0KV7024R. 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-7-hydroxy-4b-(phenylmethyl)-7-(1-propyn-1-yl)-N-(3-pyridinylmethyl)-, (4bS,7R,8aR)-. Grade: ≥95%. CAS No. 305821-96-9. Molecular formula: C31H32N2O2. Mole weight: 464.24. | |
| CP-47947 | CP-47947. Group: Biochemicals. Alternative Names: rel-5- (1, 1-dimethylheptyl) -2- [ (1R, 3S) -3-hydroxycyclohexyl] phenol; (+/-)-CP 47497; CP 47947. Grades: Highly Purified. CAS No. 70434-82-1. Pack Sizes: 1mg, 2mg. Molecular Formula: C21H34O2. US Biological Life Sciences. | Worldwide |
| CP-47947 Benzyl Ether | CP-47947 derivative. A cannabinoid receptor ligand. Group: Biochemicals. Alternative Names: cis-3-[4-(1,1-Dimethylheptyl)-2-(phenylmethoxy)phenyl]-cyclohexanol. Grades: Highly Purified. CAS No. 70434-49-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| CP-481715 | CP-481715 is a potent and selective CCR1 antagonist with >100-fold selective for CCR1 as compared with a panel of G-protein-coupled receptors including related chemokine receptors. CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice. Synonyms: N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide; CP 481,715; CP 481715; CP-481,715; CP-481715; CP481,715; CP481715; quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide. Grade: >98%. CAS No. 212790-31-3. Molecular formula: C26H31FN4O4. Mole weight: 482.55. | |
| Cp4G | Cp4G, an invaluable compound extensively used in the biomedical sector to study G protein-coupled receptors (GPCRs) is bestowed with unmatched affinity towards GPR120, a receptor that holds immense therapeutic promise to combat obesity and type 2 diabetes. Having demonstrated pronounced efficacy, Cp4G presents an exciting avenue for drug development in the fight against these rampant maladies. Synonyms: P1- (5'- Cytidyl)- P4- (5'- guanosyl)- tetraphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 79695-24-2. Molecular formula: C19H28N8O21P4 (free acid). Mole weight: 828.4 (free acid). | |
| CP-5068 | CP-5068 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CP-5068; CP 5068; CP5068; UNII-0UZY88DX6N. (4S,5R,6S)-3-[6-(2-amino-2-oxoethyl)-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: ≥98%. CAS No. 352305-79-4. Molecular formula: C18H20N4O5S2. Mole weight: 436.08. | |
| CP 524515 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP 532623 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-532623 | CP-532623, structurally related to Torcetrapib, is a potent inhibitor of cholesteryl ester transfer protein (CETP). Synonyms: CP-532623; CP 532623; CP532623; UNII-5KK52HG8D; 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile. Grade: >98%. CAS No. 261947-38-0. Molecular formula: C27H27F9N2O3. Mole weight: 598.5. | |
| CP-533536 | CP-533536, also called as Evatanepag, a 3-pyridyl sulfonamide compound, demonstrated excellent in vitro potency against prostaglandin E2 (PGE2) (induces local bone formation with EC50= 0.3 nM) and selectivity against a broad panel of other targets. Synonyms: 2-[3-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetic acid(3-((4-tert-butylbenzyl)-(pyridine-3-sulfonylamino)methyl)phenoxy)acetic acidCP-533536; CP 533536; CP533536; Evatanepag. Grade: 95%. CAS No. 223488-57-1. Molecular formula: C25H28N2O5S. Mole weight: 468.56. | |
| CP-53631 | CP-53631 is a selective serotonin reuptake inhibitor (SSRI); antidepressant. Group: Biochemicals. Alternative Names: (1R,4S)-rel-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-(±)-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride. Grades: Highly Purified. CAS No. 79836-56-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CP-53631 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP 544326 | CP 544326, also known as taprenepag, is a potent and selective EP(2) receptor agonist. Its EC50 value is 2.8 nM. It is the active acid metabolite of the prodrug PF-04217329. It was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Uses: Cp 544326 was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Synonyms: CP-544326; CP544326, CP544326, Taprenepag, PF-0421732 metabolite; 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetic acid; CP-544326; CP544326; CP544326; Taprenepag; PF-0421732 metabolite. Grade: 98%. CAS No. 752187-80-7. Molecular formula: C24H22N4O5S. Mole weight: 478.52. | |
| CP-544439 | CP-544439 is a selective matrix metalloproteinase-13 inhibitor. Uses: Matrix metalloproteinase inhibitors. Synonyms: 4-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxyoxane-4-carboxamide; CP-544439; CP 544439; CP544439 ; UNII-516DO4KL5R. Grade: >98%. CAS No. 230954-09-3. Molecular formula: C18H19FN2O6S. Mole weight: 410.42. | |
| CP-547632 | CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). It is selective relative to epidermal growth factor receptor, platelet-derived growth factor , and other related TKs. It also inhibits VEGF-stimulated autophosphorylation of VEGFR-2 in a whole cell assay with an IC50 value of 6 nM. After oral administration of CP-547,632 to mice bearing NIH3T3/H-ras tumors, VEGFR-2 phosphorylation in tumors was inhibited in a dose-dependent fashion (EC50 590 ng/ml). CP-547,632 is a well-tolerated, orally-bioavailable inhibitor presently under clinical investigation for the treatment of human malignancies. Synonyms: CP547632; CP 547632; CP-547632; PAN90806; PAN 90806; PAN-90806; CP632; OSI632; CP 632; OSI 632; CP-632; OSI-632. CAS No. 252003-65-9. Molecular formula: C20H24BrF2N5O3S. Mole weight: 532.405. | |
| CP-547632 hydrochloride | CP-547632 hydrochloride is a potent, orally active and ATP-competitive inhibitor of VEGFR-2 and FGF kinases with IC50s of 11 and 9 nM, respectively. It is selective for VEGFR2 and bFGF over EGFR, PDGFRβ and related tyrosine kinases (TKs). It has antitumor effect. Synonyms: 3-[(4-Bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-Isothiazolecarboxamide hydrochloride; PF-01371182 hydrochloride; 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-({[4-(1-pyrrolidinyl)butyl]carbamoyl}amino)-1,2-thiazole-4-carboxamide hydrochloride (1:1); 4-Isothiazolecarboxamide, 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-, hydrochloride (1:1). Grade: ≥98%. CAS No. 252003-71-7. Molecular formula: C20H25BrClF2N5O3S. Mole weight: 568.86. | |
| CP-547632 hydrochloride | CP-547632 hydrochloride is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 hydrochloride is selective for VEGFR2 and bFGF over EGFR, PDGFR?, and related tyrosine kinases (TKs). CP-547632 hydrochloride has antitumor efficacy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 252003-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13302B. | |
| CP-547632 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CP-547632 TFA | CP-547632 TFA is a potent, orally active and ATP-competitive inhibitor of VEGFR-2 and FGF kinases with IC50s of 11 and 9 nM, respectively. It is selective for VEGFR2 and bFGF over EGFR, PDGFRβ and related tyrosine kinases (TKs). It has antitumor effect. Synonyms: 3-((4-bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide 2,2,2-trifluoroacetate. Grade: ≥98%. Molecular formula: C22H25BrF5N5O5S. Mole weight: 646.43. | |
| CP-5484 | CP-5484 is a synthetic bio-active chemical with potent anti-MRSA activity and low acute toxicity. Uses: A synthetic bio-active chemical with potent anti-mrsa activity and low acute toxicity. Synonyms: CP-5484; CP 5484; CP5484; UNII-A53TMV6VUN. (4S,5R,6S)-3-[6-[(2R)-3-amino-2-hydroxypropyl]-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; chloride. Grade: ≥98%. CAS No. 352308-27-1. Molecular formula: C19H25ClN4O5S2. Mole weight: 489.00. | |
| CP-5609 | CP-5609 is a novel carbapenem with enhanced antimicrobial activities. Uses: Antimicrobial activities. Synonyms: CP-5609; CP 5609; CP5609; ME-1036; ME 1036; ME1036; UNII-33501R83O2. Pyridinium, 1-(2-amino-2-oxoethyl)-3-((2-((4S,5R,6S)-2-carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)imidazo(5,1-b)thiazol-7-yl)carbonyl)-, inner salt. Grade: ≥95%. CAS No. 432038-96-5. Molecular formula: C23H21N5O6S. Mole weight: 495.51. | |
| CP 59430 | CP 59430 is an azide analog of prazosin. It is a selective alpha 1-adrenergic receptor antagonist. Synonyms: CP 59430; CP59430; CP-59430. 2-(4-(4-Azidobenzoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline. Grade: 98%. CAS No. 86329-06-8. Molecular formula: C21H22N8O3. Mole weight: 434.45. | |
| CP-601927 | CP-601927 is a CNS-penetrant, high affinity, and selective nicotinic acetylcholine receptor (nAChR) agonist. Uses: Nachr agonist. Synonyms: CP-601927; CP 601927; CP601927; CP-601,927; UNII-VI5LR1EU47; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-. Grade: ≥98%. CAS No. 357425-02-6. Molecular formula: C12H12F3N. Mole weight: 227.09. | |
| CP-601932 | CP-601932 is a CNS-penetrant, high affinity, and selective α(4) β(2) nicotinic acetylcholine receptors partial agonist. Uses: Nachr agonist. Synonyms: CP-601932; CP 601932; CP601932; CP-601,927; UNII-VI5LR1EU47; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-. Grade: ≥98%. CAS No. 357425-68-4. Molecular formula: C12H12F3N. Mole weight: 227.23. | |
| CP-608039 | CP-608039 is a selective adenosine A3 receptor agonist with 1,260-fold selectivity for the human A3 versus human A1 receptor. Uses: A selective adenosine a3 receptor agonist. Synonyms: CP-608039; CP608039; CP 608039; UNII-A1LB8I4247. (2S,3S,4R,5R)-3-amino-5-[6-[[5-chloro-2-[(3-methyl-1,2-oxazol-5-yl)methoxy]phenyl]methylamino]purin-9-yl]-4-hydroxy-N-methyloxolane-2-carboxamide. Grade: ≥98%. CAS No. 331727-55-0. Molecular formula: C23H25ClN8O5. Mole weight: 528.16. | |
| CP-60949-4 | CP-60949-4, a quinazolin derivative, could be probably useful in sorts of biological studies. Synonyms: CP 60949-4; CP60949-4; CP-609494. AC1L1YFM; CP 60949-4; 6-bromo-7-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]quinazolin-4-one hydrobromide; 4(3H)-Quinazolinone, 6-bromo-7-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-, monohydrobromide. Grade: 98%. CAS No. 17518-97-7. Molecular formula: C16H18Br2ClN3O3. Mole weight: 495.60. | |
| CP-609754 | CP-609754, also known as CP-609,754,LNK 754 and OSI 754, is a potent arnesyltransferase inhibitor with potential anticancer activity. Synonyms: CP-609754; CP609754; CP 609754; CP-609,754; CP609,754; CP 609,754; LNK 754; LNK754; LNK-754; OSI 754; OSI754; OSI-754. CAS No. 1190094-64-4. Molecular formula: C29H22ClN3O2. Mole weight: 479.964. | |
| CP 615003 mesylate | CP 615003 mesylate is a potent and selective GABAA receptor partial agonist potentially useful in treating generalized anxiety disorder. Uses: Potential treatment of anxiety. Synonyms: CP 615003 mesylate; CP615003 mesylate; CP-615003 mesylate; N-(3-fluoro-4-(2-(propylamino)ethoxy)phenyl)-4,5,6,7-tetrahydro-4-oxo-1H-indole-3-carboxamide mesylate. Grade: 99%. CAS No. 1259477-42-3. Molecular formula: C20H24FN3O3.CH4O3S. Mole weight: 469.53. | |
| CP 6232 | CP 6232 is a new anti-pseudomonal cephalosporin as a cell wall inhibitor. It was developed by Meiji Seika Pharma. Research for the treatment of bacterial infections was discontinued. Uses: Bacterial infections. Synonyms: CP 6232; CP6232; CP-6232. 7-((2-Aminothiazol-4-yl)-2-(1-carboxy-1-methyl)ethoxyiminoacetamido)-3-(N-(1,5-dihydroxy-4-pyridon-2-yl)methyl-N-methyl)aminomethyl-3-cephem-4-carboxylic acid. Grade: 98%. CAS No. 141562-38-1. Molecular formula: C24H27N7O10S2. Mole weight: 637.65. | |
| CP-628006 | CP-628006 is a small molecule CFTR potentiator that restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. (US8901310, Comparator A). Synonyms: (4bS,7S,8aR)-4b-Benzyl-7-hydroxy-N-[(2-methyl-3-pyridinyl)methyl]-7-(3,3,3-trifluoropropyl)-4b,5,6,7,8,8a,9,10-octahydro-2-phenanthrenecarboxamide; 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-7-hydroxy-N-[(2-methyl-3-pyridinyl)methyl]-4b-(phenylmethyl)-7-(3,3,3-trifluoropropyl)-, (4bS,7S,8aR)-. CAS No. 305822-08-6. Molecular formula: C32H35F3N2O2. Mole weight: 536.63. | |
| CP-640186 | CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs. Synonyms: CP-640186; CP 640186; CP640186. Grade: >98%. CAS No. 591778-68-6. Molecular formula: C30H35N3O3. Mole weight: 485.62. | |
| CP-640186 | CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259. | |
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