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Specific for coniferyl alcohol; does not act on cinnamyl alcohol, 4-coumaryl alcohol or sinapyl alcohol. Group: Enzymes. Synonyms: CAD (ambiguous). Enzyme Commission Number: EC 1.1.1.194. CAS No. 37250-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0097; coniferyl-alcohol dehydrogenase; EC 1.1.1.194; 37250-27-4; CAD (ambiguous). Cat No: EXWM-0097.
Sinapyl alcohol can also act as acceptor. Group: Enzymes. Synonyms: uridine diphosphoglucose-coniferyl alcohol glucosyltransferase; UDP-glucose coniferyl alcohol glucosyltransferase. Enzyme Commission Number: EC 2.4.1.111. CAS No. 61116-23-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2338; coniferyl-alcohol glucosyltransferase; EC 2.4.1.111; 61116-23-2; uridine diphosphoglucose-coniferyl alcohol glucosyltransferase; UDP-glucose coniferyl alcohol glucosyltransferase. Cat No: EXWM-2338.
Also oxidizes other aromatic aldehydes, but not aliphatic aldehydes. Group: Enzymes. Enzyme Commission Number: EC 1.2.1.68. CAS No. 208540-41-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1169; coniferyl-aldehyde dehydrogenase; EC 1.2.1.68; 208540-41-4. Cat No: EXWM-1169.
Coniferyl ferulate
Coniferyl ferulate is an orally active phenolic acid compound. Coniferyl ferulate is a potent inhibitor of glutathione S-transferase (GST) (IC50 = 0.3 μM), which downregulates P-gp expression, induces apoptosis in B-MD-C1 (ADR+/+) cells, and reverses multidrug resistance. Coniferyl ferulate blocks the NMDAR/NR2B-CaMKII-MAPKs signaling pathway, inhibits ROS production and mitochondrial apoptosis, while reshapes the intestinal microbiota and microbial metabolism, ameliorates colonic inflammation and alleviates depressive symptoms in mice. Coniferyl ferulate can alleviate the toxicity of xylene to hematopoietic stem and progenitor cells by targeting Mgst2. Coniferyl ferulate exhibits antibacterial activity against the Gram-positive Bacillus subtilis and Staphylococcus aureus[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63644-62-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N1916.
Coniine hydrobromide
Coniine hydrobromide is a polyketide-derived alkaloid that is toxic to humans and animals. It is a nicotinic acetylcholine receptor antagonist that causes inhibition of the nervous system. Synonyms: Piperidine, 2-propyl-, hydrobromide (1:1), (2S)-; Piperidine, 2-propyl-, moohydrobromide, (2S)-; Piperidine, 2-propyl-, hydrobromide, (S)-; (S)-Coniine hydrobromide; (+)-Coniine hydrobromide; (S)-(+)-Coniine hydrobromide; (S)-2-Propylpiperidine hydrobromide. Grade: ≥95%. CAS No. 637-49-0. Molecular formula: C8H17N.HBr. Mole weight: 208.14.
Coniine hydrochloride
Coniine hydrochloride is a polyketide-derived alkaloid that is toxic to humans and animals. It is a nicotinic acetylcholine receptor antagonist that causes inhibition of the nervous system. Synonyms: Piperidine, 2-propyl-, hydrochloride (1:1), (2S)-; Piperidine, 2-propyl-, monohydrochloride, (2S)-; Piperidine, 2-propyl-, hydrochloride, (S)-; (+)-Coniine hydrochloride; (S)-(+)-Coniine hydrochloride; (S)-2-Propylpiperidine hydrochloride; (S)-Coniine hydrochloride; NSC 15128. Grade: ≥95%. CAS No. 555-92-0. Molecular formula: C8H17N.HCl. Mole weight: 163.69.
Coniosetin
It is produced by the strain of Coniochaeta ellipsoidea DSM 13856. It has activity against gram-positive bacteria, including clinical separation of multidrug resistant staphylococcus aureus and resistant to erythromycin streptococcus pneumoniae (MIC is 0.3-0.6 μg/mL), S. pyogenes, dung enterococcus and excrement enterococcus (MIC is 1.2-2.5 μg/mL). It has certain effect on yeast such as Candida albicans (MIC is 3.1 μg/mL). It has weak activity against gram-negative bacteria and other fungi. Synonyms: (5S)-5-[(S)-1-Hydroxyethyl]-3-[[1,2,4abeta,5,6,7,8,8aalpha-octahydro-1beta,3,6alpha-trimethyl-2alpha-[(1E,3E)-1,3-pentadienyl]naphthalene-1-yl]hydroxymethylene]pyrrolidine-2,4-dione. Molecular formula: C25H35NO4. Mole weight: 413.55.
Conivaptan
Conivaptan, also called as YM 087 or Vaprisol, is the first is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) approved by United States Federal Drug Administrations (FDA) for the treatment of hyponatremia. Synonyms: [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-; N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl][1,1'-biphenyl]-2-carboxamide; ZINC 12503187; N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 95%. CAS No. 210101-16-9. Molecular formula: C32H26N4O2. Mole weight: 498.58.
Conivaptan-d4
Conivaptan-d4 is a labelled Conivaptan. Conivaptan is an arginine vasopressin (AVP) receptor inhibitor approved for the treatment of decompensated congestive heart failure. Grade: > 95%. CAS No. 1129433-63-1. Molecular formula: C32H22N4O2D4. Mole weight: 502.61.
Conivaptan hydrochloride
Conivaptan HCl is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist). Uses: Antidiuretic hormone receptor antagonists. Synonyms: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1); [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride; Conivaptan monohydrochloride. Grade: >98%. CAS No. 168626-94-6. Molecular formula: C32H26N4O2.HCl. Mole weight: 535.04.
Conivaptan hydrochloride
Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: YM 087. CAS No. 168626-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18347A.
Conivaptan Hydrochloride
Used in treatment of congestive heart failure. Group: Biochemicals. Alternative Names: N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride; Vaprisol; YM 087. Grades: Highly Purified. CAS No. 168626-94-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Conivaptan Hydrochloride
Conivaptan hydrochloride is a nonpeptide, dual antagonist of arginine vasopressin receptors approved for intravenous use in hospitalized patients. As the hydrochloride salt formulation, it was initially approved by the FDA in 2005 for raising serum sodium levels in euvolemic and hypervolemic hyponatremia. Applications: Conivaptan hydrochloride is indicated to raise serum sodium in hospitalized patients with euvolemic or hypervolemic hyponatremia associated with conditions such as syndrome of inappropriate antidiuretic hormone secretion, heart failure, or cirrhosis. the drug is contraindicated in hypovolemic hyponatremia, anuria, and with potent cyp3a inhibitors, and its use is limited to short-term inpatient management. Category: Diuretic apis. Synonyms: Vaprisol; YM087; CI-1025. CAS No. 168626-94-6. Product ID: API0232082. Molecular formula: C32H27ClN4O2. Mole weight: 535.04. EINECS: 111-171-7. InChIKey: BTYHAFSDANBVMJ-UHFFFAOYSA-N. Appearance: White to off-white powder.
Conivaptan hydrochloride Impurity D
Conivaptan hydrochloride Impurity D is an impurity of Conivaptan hydrochloride, a therapeutic agent instrumental in rectifying specific fluid and electrolyte disturbances. CAS No. 168626-74-2.
Conivaptan hydrochloride Impurity E
Conivaptan hydrochloride Impurity E is an impurity of Conivaptan hydrochloride, a drug for treatig an array of medical afflictions, encompassing acute hyponatremia and congestive heart failure. CAS No. 877858-27-0.
Conivaptan hydrochloride Impurity G
Conivaptan hydrochloride Impurity G acts as an impurity in conivaptan hydrochloride, a medication used to manage euvolemic and hypervolemic hyponatremia in hospitalized patients. CAS No. 168626-93-5.
Conivaptan hydrochloride Impurity H
Conivaptan Hydrochloride Impurity H is an impurity of Conivaptan Hydrochloride, presenting as a pivotal therapeutic intervention for a heterogeneous spectrum of afflictions encompassing heart failure, hyponatremia and liver cirrhosis. Operating diligently as a potent inhibitor, Conivaptan Hydrochloride orchestrates the regulation of arginine vasopressin, efficaciously fostering diuresand reinstating homeostasis pertaining to electrolyte equilibrium within the corporeal domain. Synonyms: 4-bromo-1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 4-bromo-1-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-1-benzazepin-5-one; 4-BROMO-1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE; 4-bromo-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one; 5H-1-Benzazepin-5-one, 4-bromo-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-; Conivaptan hydrochloride Impurity H; NSC140796; SCHEMBL19149798; DTXSID40301048; BCP18303; NSC-140796; F19329; A899571; AN-975/13811041. CAS No. 29489-04-1. Molecular formula: C17H16BrNO3S. Mole weight: 394.3.
Conivaptan hydrochloride Impurity I
Conivaptan hydrochloride Impurity I is an impurity encountered in Conivaptan hydrochloride. Conivaptan hydrochloride is an extensively employed pharmaceutical agent efficacious in treating hyponatremia as well as fluid retention linked with congestive heart failure and hepatic ailments. CAS No. 717917-14-1.
Conivaptan impurity A
Conivaptan impurity A. Uses: For analytical and research use. Alternative Names: [1,1'-biphenyl]-2-carboxylic acid. CAS No. 947-84-2. Molecular formula: C13H10O2. Mole weight: 198.22. Catalog: APB947842.
Conivaptan impurity B
Conivaptan impurity B. Uses: For analytical and research use. Alternative Names: 4-aminobenzoic acid. CAS No. 150-13-0. Molecular formula: C7H7NO2. Mole weight: 137.14. Catalog: APB150130.
Conivaptan impurity C
Conivaptan impurity C. Uses: For analytical and research use. Alternative Names: 2-methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine. CAS No. 318237-73-9. Molecular formula: C12H13N3. Mole weight: 199.25. Catalog: APB318237739.
Conivaptan impurity D
Conivaptan impurity D. Uses: For analytical and research use. Alternative Names: 4-[([1,1'-Biphenyl]-2-carbonyl)amino]benzoic Acid. CAS No. 168626-74-2. Molecular formula: C20H15NO3. Mole weight: 317.34. Catalog: APB168626742.
Conivaptan impurity E
Conivaptan impurity E. Uses: For analytical and research use. Alternative Names: 2-methyl-5,6-dihydro-4Hbenzo[b]oxazolo[5,4-d]azepine. CAS No. 877858-27-0. Molecular formula: C12H12N2O. Mole weight: 200.24. Catalog: APB877858270.
Conivaptan impurity F
Conivaptan impurity F. Uses: For analytical and research use. Alternative Names: N-(4-(2-methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. Molecular formula: C32H26N4O2. Mole weight: 498.57. Catalog: APB04194.
Conivaptan impurity G
Conivaptan impurity G. Uses: For analytical and research use. Alternative Names: N-(4-(2-methyl-5,6-dihydro-4Hbenzo[b]oxazolo[5,4-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide. CAS No. 168626-93-5. Molecular formula: C32H25N3O3. Mole weight: 499.56. Catalog: APB168626935.
Conivaptan impurity H
Conivaptan impurity H. Uses: For analytical and research use. Alternative Names: 4-bromo-1-tosyl-3,4-dihydro-1Hbenzo[b]azepin-5(2H)-one. CAS No. 29489-04-1. Molecular formula: C17H16BrNO3S. Mole weight: 394.28. Catalog: APB29489041.
Conivaptan impurity I
Conivaptan impurity I. Uses: For analytical and research use. Alternative Names: 2-Methyl-6-[(4-methylphenyl)sulfonyl]-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepine. CAS No. 717917-14-1. Molecular formula: C19H19N3O2S. Mole weight: 353.44. Catalog: APB717917141.
Conjugated estrogen EP impurity B
Conjugated estrogen EP impurity B. Uses: For analytical and research use. CAS No. 56050-05-6. Molecular formula: C18H21NaO5S. Mole weight: 372.41. Catalog: APB56050056.
Conjugated estrogen impurity 1
Conjugated estrogen impurity 1. Uses: For analytical and research use. CAS No. 481-97-0. Molecular formula: C18H22O5S. Mole weight: 350.43. Catalog: APB481970.
Conjugated estrogens
Conjugated estrogens is a complex mixture of sodium estrone sulfate and sodium equilin sulfate derived synthetically from estrone and equilin or extracted from pregnant mares' urine. Uses: Estrogens. Synonyms: Estrogens, conjugated; Estrogens, conjugates (12C); Ayerogen; Ayerogen Crema Vaginal; Azumon; C.E.S.; Cenestin; Climarest; Conjugated equine estrogen; Conjugates, estrogens; Conjugen; Dagynil; Emopremarin; Equin; Femavit; Hyphorin; Mannest; Menopak E; Menpoz; Neo-Menovar; Oestro-Feminal; Ovest; Premaril; Premarin; Premarin Crema V; Premarin Creme; Premarin Vaginal Creme; Premarina; Premarose; Presomen; Prevagin-Premaril; Romeda; Sefac; Srogen; Sukingpo; Transannon. Grade: 95%. CAS No. 12126-59-9. Molecular formula: C18H19NaO5S. Mole weight: 370.4.
Conjugated Estrogens
Conjugated Estrogens. Group: Biochemicals. Grades: Highly Purified. CAS No. 12126-59-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Conjugated Linoleic Acid Ethyl Ester, 90%. (Mixture of Isomers)
Conjugated Linoleic Acid Ethyl Ester is the ethyl ester derivative of Conjugated Linoleic Acid (C685000); a compound that has reported to exhibit anticarcinogenic activity. Also a potent antioxidant. Group: Biochemicals. Grades: Highly Purified. CAS No. 137142-61-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H36O2, Molecular Weight: 308.5. US Biological Life Sciences.
Conjugated Linoleic Acid Methyl Ester, 90%. (Mixture of Isomers)
Conjugated Linoleic Acid Methyl Ester is the methyl ester derivative of Conjugated Linoleic Acid (C685000); a compound that has reported to exhibit anticarcinogenic activity. Also a potent antioxidant. Group: Biochemicals. Grades: Highly Purified. CAS No. 1002-79-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H34O2, Molecular Weight: 294.47. US Biological Life Sciences.
Worldwide
Connexin mimetic peptide 40GAP27
Connexin mimetic peptide 40GAP27 is a biological active peptide. (This peptide corresponds to the GAP27 domain of the second extracellular loop of dominant vascular connexin (Cx40), designated as 40Gap 27. It was used to investigate mechanisms through which oxidant stress impairs communication via gap junctions. When administered, 40Gap27attenuates endothelium-dependent subintimal smooth muscle hyperpolarization.). Uses: Scientific research. Category: Signaling pathways. CAS No. 403858-30-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P5389.
Conocandin
It is produced by the strain of Hormococcus conorium. It has strong antifungal activity. Synonyms: 2-Methylidene-10-methyl-trans-3,4-epoxy-9-hexadecenoic acid. CAS No. 61371-61-7. Molecular formula: C18H30O3. Mole weight: 294.43.
Conoidin A
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII)[1][2]. Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18080-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 100 mg. Product ID: HY-116090.
Conoidin A
Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. Synonyms: 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide. Grade: ≥98%. CAS No. 18080-67-6. Molecular formula: C10H8Br2N2O2. Mole weight: 348.
Conolysin-Mt2
Conolysin-Mt2 was found in Weasel cone (Conus mustelinus). It has antibacterial activity.
Conopharyngine
Conopharyngine is isolated from the herbs of Voacanga africana. Synonyms: 12,13-Dimethoxyibogamine-18-carboxylic acid methyl ester. Grade: 96.5%. CAS No. 76-98-2. Molecular formula: C23H30N2O4. Mole weight: 398.5.
Conophylline
Conophylline is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142741-24-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3619.
Conopressin G
Conopressin G is a vasotocin-like peptide isolated from the venom of the worm-hunting snail (conus imperialis). Synonyms: Glycinamide, L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1→6)-disulfide; Conopressin G (Conus geographus); Conopressin L1; Lysine-conopressin (Erpobdella octoculata); Lysine-conopressin (Lymnaea stagnalis); H-Cys-Phe-Ile-Arg-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Lys-Conopressin-G. Grade: 95%. CAS No. 111317-91-0. Molecular formula: C44H71N15O10S2. Mole weight: 1034.26.
Conopressin S
Conopressin S, isolated from Conus striatus, has a high affinity with vasopressin V1b receptor (AVPR1B). Synonyms: Con-S; Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Conopressin A1; L-cysteinyl-L-isoleucyl-(3S)-DL-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Grade: ≥95% by HPLC. CAS No. 111317-90-9. Molecular formula: C41H73N17O10S2. Mole weight: 1028.26.
Conopressin S acetate
Conopressin S acetate, isolated from Conus striatus, has a high affinity with vasopressin V1b receptor (AVPR1B) with a Ki of 8.3 nM. Synonyms: Con-S acetate; Conopressin A1 acetate; H-Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-isoleucyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide acetate. Grade: ≥95%. Molecular formula: C43H77N17O12S2. Mole weight: 1088.32.
Conorlobaridone
It is the depsidone isolated from the lichen Xanthoparmelia xanthosorediata. Synonyms: 3,8-Dihydroxy-1-pentanoyl-6-propyl-dibenzo[b,e][1,4]dioxepin-11-one; Conlorlobaridon; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 3,8-dihydroxy-1-(1-oxopentyl)-6-propyl-. CAS No. 71521-80-7. Molecular formula: C21H22O6. Mole weight: 370.40.
Conphysodalic acid
Conphysodalic acid is a secondary metabolite of the lichen Hypogymnia physodes. CAS No. 111720-42-4. Molecular formula: C20H18O10. Mole weight: 418.35.
Conprotocetraric acid
Conprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Usnea trichodeoides. Synonyms: 6,14-dihydroxy-7,15-bis(hydroxymethyl)-4,12-dimethyl-10-oxo-2,9-dioxatricyclo[9.4.0.0(3,8)]pentadeca-1(11),3(8),4,6,12,14-hexaene-5-carboxylic acid; 3,8-dihydroxy-4,9-bis(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C18H16O9. Mole weight: 376.31.
Conquinamine
Conquinamine is a natural alkaloid isolated from Cinchona ledgeriana. . Synonyms: Epiquinamine,3-epi-Quinamine. Grade: >98%. CAS No. 464-86-8. Molecular formula: C19H24N2O2. Mole weight: 312.41.
Conquinine
Conquinine is a Cytochrome P450 2D6 inhibitor. It is a dextrorotatory stereoisomer of quinine extracted from the bark of the Cinchona tree and similar plant species. It is an alkaloid with class 1A antiarrhythmic and antimalarial effects. It also blocks muscarinic and alpha-adrenergic neurotransmission. It stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thus inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. It acts primarily as an intra-erythrocytic schizonticide through association with the heme polymer (hemazoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. Uses: Conquinine is an alkaloid with class 1a antiarrhythmic and antimalarial effects. it also blocks muscarinic and alpha-adrenergic neurotransmission. Synonyms: Quinidine; Chinidin; Pitayine; (+)-Quinidine; Quinidex; Chinidin; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. Grade: 98%. CAS No. 56-54-2. Molecular formula: C20H24N2O2. Mole weight: 324.42.
Constipatic acid, a fatty acid found in several lichen species, has been isolated from Xanthoparmelia constipata, Parmelia xanthosorediata, Heterodermia appendiculata, Lepraria coriensis, Punctelia negata and Rhizoplaca melanophthalma and so on. Synonyms: 2-(14'-hydroxypentadecyl)-4-methyl-5-oxo-2,5-dihydrofuran-3-carboxylic acid. CAS No. 73036-28-9. Molecular formula: C21H36O5. Mole weight: 368.51.
Consuccinprotocetraric acid
Consuccinprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Flavoparmelia succinprotocetrarica. Synonyms: 9-(((3-carboxypropanoyl)oxy)methyl)-3,8-dihydroxy-4-(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C22H20O12. Mole weight: 476.39.
Container Resins
Container Resins.
Conteltinib
Conteltinib is a multikinase inhibitor that targets FAK, ALK and Pyk2 and has a significant inhibitory effect on FAK with an IC50 of 1.6 nM. Uses: Protein kinase inhibitors. Synonyms: CT-707; Benzenesulfonamide, 2-[[6,7-dihydro-2-[[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-N-(1-methylethyl)-. Grade: ≥95%. CAS No. 1384860-29-0. Molecular formula: C32H45N9O3S. Mole weight: 635.82.
Contezolid
Contezolid is a new and orally active oxazolidinone. It is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI). Synonyms: MRX-I; Lascufloxacin; (S)-5-((isoxazol-3-ylamino)methyl)-3-(2,3,5-trifluoro-4-(4-oxo-3,4-dihydropyridin-1(2H)-yl)phenyl)oxazolidin-2-one. CAS No. 1112968-42-9. Molecular formula: C18H15F3N4O4. Mole weight: 408.33.
Contezolid
Contezolid (MRX-I) is an orally available oxazolidinone antibiotic with bactericidal activity that can be used to study complications of skin tissue infections and tuberculosis caused by drug-resistant Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 1112968-42-9. Product ID: API1112968429. Molecular formula: C18H15F3N4O4. Mole weight: 408.33.
Contezolid acefosamil
Contezolid acefosamil (MRX-4), an orally active prodrug, is metabolized into Contezolid (MRX-I), an oxazolidinone derivative with potent in vitro efficacy against multidrug-resistant Gram-positive bacteria, including MRSA. Category: Active pharmaceutical ingredients. CAS No. 1807497-11-5. Product ID: API1807497115. Molecular formula: C20H18F3N4O8P. Mole weight: 530.353.
Contezolid acefosamil sodium
Contezolid acefosamil sodium (MRX-4) is a novel orally active oxazolidinone antibiotic under investigation for the treatment of complicated skin and soft tissue infections (cSSTI) caused by drug-resistant Gram-positive bacteria. It possesses strong efficacy against these pathogens while significantly minimizing the risks of myelosuppression and monoamine oxidase inhibition (MAOI). Category: Active pharmaceutical ingredients. CAS No. 1807365-35-0. Product ID: API1807365350. Molecular formula: C20H18F3N4NaO8P. Mole weight: 553.343.
Continentalic acid
Continentalic acid is a diterpenoid organic acid. Continentalic acid exhibits multiple activities including anti-inflammatory, antioxidant, neuroprotective, antibacterial and antitumor effects. Continentalic acid alleviates oxidative stress, reduces pro-inflammatory cytokine production, inhibits MAPK phosphorylation and neutrophil infiltration, and induces growth inhibition and apoptosis of cancer cells. Continentalic acid can be used in research related to traumatic brain injury, cancer, inflammation and infections[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19889-23-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6908.
Contortin
It was the first intestinal antigen of the sheep parasite Haemonchus contortus and was used to induce significant levels of protection when inoculated in lambs. Synonyms: 1,1'-(2,2'-dihydroxy-4,4',6,6'-tetramethoxy-5,5'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(ethan-1-one); Ethanone, 1,1'-(2,2'-dihydroxy-4,4',6,6'-tetramethoxy-5,5'-dimethyl(1,1'-biphenyl)-3,3'-diyl)bis-. CAS No. 91925-83-6. Molecular formula: C22H26O8. Mole weight: 418.44.
Control Liposome
Control Liposome are recognized and phagocytosed by the same mechanism as Clodronate Liposome, which do not contain clodronate, thus the phagocytic cells are not killed. However, phagocytes do respond to the ingestion of control liposomes by cytokine secretion, temporary suspension of phagocytic activity and other responses. Group: Clodronate liposome.