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A diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus. It is a secondary metabolite found in various marine fungi and bacteria. It is capable of activating N-acylhomoserine lactones (ahls), also capable of activating or antagonizing other luxr-based quorum-sensing systems. Synonyms: (3S-trans)-Hexahydro-3-(1-methylethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione; (S,S)-Hexahydro-3-isopropyl-pyrrolo[1,2-a]pyrazine-1,4-dione; (-)-(6S,9S)-Cyclo(prolylvalyl); Cyclo(L-Val-L-Pro); Cyclo(L-prolyl-L-valine); Cyclo(L-prolyl-L-valyl); L-Valyl-L-prolyl lactam; Maculosin 5. Grade: >98% by HPLC. CAS No. 2854-40-2. Molecular formula: C10H16N2O2. Mole weight: 196.25.
Cyclo(-L-Ser-L-Tyr) 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Cyclo(L-Trp-L-Trp)
Cyclo(L-Trp-L-Trp). Group: Biochemicals. Alternative Names: Cyclo(-Trp-Trp). Grades: Highly Purified. CAS No. 20829-55-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Cyclo(L-Trp-L-Trp)
Cyclo(L-Trp-L-Trp) is a cyclic dipeptide with antibacterial activity. It inhibits the growth of 41 out of 49 strains of multidrug resistant A. baumannii as well as B. subtilis, M. luteus, S. aureus, S. cerevisiae, A. niger and C. albicans. It has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines. Synonyms: Cyclo(-Trp-Trp). Grade: ≥98%. CAS No. 20829-55-4. Molecular formula: C22H20N4O2. Mole weight: 372.42.
Cyclo(L-Trp-L-Trp)
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20829-55-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-P2124.
Cyclo(L-Trp-L-Trp) 98+% (HPLC)
Cyclo(L-Trp-L-Trp) 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Cyclo(-L-Trp-L-Tyr)
Cyclo(-L-Trp-L-Tyr). Group: Biochemicals. Alternative Names: Cyclo(-Trp-Tyr). Grades: Highly Purified. CAS No. 20829-53-2. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
Cyclo(-L-Trp-L-Tyr) 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
cyclo(L-Tyr-L-Val)
Cyclo(L-Tyr-L-Val) is a diketopiperazine metabolite isolated from marine actinomycetes (Nocardiopsis gilva). Synonyms: Cyclo(Tyr-Val). Grade: >95% by HPLC. CAS No. 21754-25-6. Molecular formula: C14H18N2O3. Mole weight: 262.3.
cyclo(L-tyrosyl-L-tyrosyl) synthase
The reaction proceeds following a ping-pong mechanism forming a covalent intermediate between an active site serine and the first L-tyrosine residue. The protein, from the bacterium Mycobacterium tuberculosis, also forms small amounts of cyclo(L-tyrosyl-L-phenylalanyl). Group: Enzymes. Synonyms: Rv2275 (gene name); cYY synthase; cyclodityrosine synthase. Enzyme Commission Number: EC 2.3.2.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2295; cyclo(L-tyrosyl-L-tyrosyl) synthase; EC 2.3.2.21; Rv2275 (gene name); cYY synthase; cyclodityrosine synthase. Cat No: EXWM-2295.
Cyclo(-L-Val-L-Phe)
Cyclo(L-Phe-L-Val) is a diketopiperazine metabolite isolated from Pseudoalteromonas sp. Grade: >95% by HPLC. CAS No. 35590-86-4. Molecular formula: C14H18N2O2. Mole weight: 246.3.
Cyclo(L-Val-L-Val). Group: Biochemicals. Alternative Names: Cyclo(-Val-Val); Val-Val diketopiperazine. Grades: Highly Purified. CAS No. 19943-16-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences.
Worldwide
Cyclo(L-Val-L-Val) 98+% (NMR)
Cyclo(L-Val-L-Val) 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
cyclomaltodextrinase
Also hydrolyses linear maltodextrin. Group: Enzymes. Synonyms: cycloheptaglucanase; cyclohexaglucanase; cyclodextrinase; cyclomaltodextrin dextrin-hydrolase (decyclizing). Enzyme Commission Number: EC 3.2.1.54. CAS No. 37288-41-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3917; cyclomaltodextrinase; EC 3.2.1.54; 37288-41-8; cycloheptaglucanase; cyclohexaglucanase; cyclodextrinase; cyclomaltodextrin dextrin-hydrolase (decyclizing). Cat No: EXWM-3917.
cyclomaltodextrin glucanotransferase
Cyclomaltodextrins (Schardinger dextrins) of various sizes (6,7,8, etc. glucose units) are formed reversibly from starch and similar substrates. Will also disproportionate linear maltodextrins without cyclizing (cf. EC 2.4.1.25, 4-α-glucanotransferase). Group: Enzymes. Synonyms: Bacillus macerans amylase; cyclodextrin glucanotransferase; α-cyclodextrin glucanotransferase; α-cyclodextrin glycosyltransferase; β-cyclodextrin glucanotransferase; β-cyclodextrin glycosyltransferas. Enzyme Commission Number: EC 2.4.1.19. CAS No. 9030-9-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2416; cyclomaltodextrin glucanotransferase; EC 2.4.1.19; 9030-09-5; Bacillus macerans amylase; cyclodextrin glucanotransferase; α-cyclodextrin glucanotransferase; α-cyclodextrin glycosyltransferase; β-cyclodextrin glucanotransferase; β-cyclodextrin glycosyltransferase; γ-cyclodextrin glycosyltransferase; cyclodextrin glycosyltransferase; cyclomaltodextrin glucotransferase; cyclomaltodextrin glycosyltransferase; konchizaimu; α-1,4-glucan 4-glycosyltransferase, cyclizing; BMA; CGTase; neutral-cyclodextrin glycosyltransferase; 1,4-α-D-glucan 4-α-D-(1,4-α-D-glucano)-transferase (cyclizing). Cat No: EXWM-2416.
Cyclomaltoheptaose hydrate
Cyclomaltoheptaose hydrate, a cyclic oligosaccharide with vast potential for drug delivery and structural studies, has been shown to effectively inhibit the activity of various enzymes implicated in diseases such as cancer and Alzheimer's. Additionally, it displays remarkable chiral resolving properties, making it a highly useful tool for separating enantiomers. Its multifaceted nature is a valuable asset in advancing numerous scientific fields. Synonyms: b-Cyclodextrin hydrate; β-Cyclodextrin, hydrate (1:x); Cycloheptaamylose hydrate; β-Cyclodextrin hydrate; Adrabetadex hydrate; β-Cycloamylose hydrate; β-Cycloheptaamylose hydrate; β-Dextrin hydrate. CAS No. 68168-23-0. Molecular formula: C42H70O35.xH2O. Mole weight: 1134.98 (anydrous basis).
Cyclomaltopentaose
Cyclomaltopentaose.
Cyclomethicone
Cyclomethicone. CAS No. 69430-24-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Cyclo(Met-Pro) could be detected in grilled and stewed beef. The cyclopeptide seems to be an important component of beef flavor. Synonyms: cyclo(methionylpropyl); Cyclo(L-Pro-L-Met-); Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-[2-(methylthio)ethyl]-, (3S,8aS)-; Cyclo(-Met-Pro); (3S,8aS)-3-[2-(Methylsulfanyl)ethyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; cyclo-(L-proline-L-methionine); cyclo(MP). Grade: ≥90%. CAS No. 53049-06-2. Molecular formula: C10H16N2O2S. Mole weight: 228.32.
Cyclomorusin
Cyclomorusin is a natural flavonoid found in the root bark of Morus alba L. Synonyms: Cyclomulberrochromene; 6,11-Dihydroxy-3,3-dimethyl-8-(2-methyl-1-propenyl)-3H,7H,8H-bis[1]benzopyrano[4,3-b:6',5'-e]pyran-7-one; Cyclomorusin A. Grade: >97%. CAS No. 62596-34-3. Molecular formula: C25H22O6. Mole weight: 418.45.
Cyclononylprodiginine
Cyclononylprodiginine is a prodigiosin antibiotic. CAS No. 34852-35-2. Molecular formula: C23H29N3O. Mole weight: 363.49.
Cyclooctanecarbaldehyde
Cyclooctanecarbaldehyde. Alternative Names: Cyclooctanecarbaldehyde;Cyclooctanecarboxaldehyde. CAS No. 6688-11-5. Product ID: ACM1749092. Molecular formula: C9H16O. Alfa Chemistry - ISO 9001:32057 Certified.
Cyclooctanone
Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. Group: Biochemicals. Alternative Names: NSC 9475. Grades: Highly Purified. CAS No. 502-49-8. Pack Sizes: 25g. US Biological Life Sciences.
Requires Mg2+. Isolated from the bacterium Streptomyces melanosporofaciens, where it is part of the biosynthesis of cyclooctatin, a potent inhibitor of lysophospholipase. Group: Enzymes. Synonyms: cetB2. Enzyme Commission Number: EC 4.2.3.146. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5160; cyclooctat-9-en-7-ol synthase; EC 4.2.3.146; cetB2. Cat No: EXWM-5160.
Cyclooctatin
It is produced by the strain of Sreptomyces melanosporofaciens M1614-43F2. It can inhibit the hemolysis phospholipase [EC 3.1.1.5] (Lyso-PL) activity. Terpentecin as substrates, it inhibits Lyso-PL, PL-A2, PL-C and PL-D with IC50 of 2.9 μg/mL, 65.0 μg/mL, 70.0 μg/mL and >100 μg/mL, respectively. Ki is 4.8 X 10-6 mol/L. Synonyms: Dicyclopenta(a,d)cyclooctene-3,4-diol,1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydro-4,9a-dimethyl-1-(hydroxymethyl)-7-(1-methylethyl)-; 1-(Hydroxymethyl)-7-isopropyl-4,9a-dimethyl-1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydrodicyclopenta[a,d]cyclooctene-3,4-diol. CAS No. 139552-97-9. Molecular formula: C20H34O3. Mole weight: 322.49.
Cyclooctene oxide
Cyclooctene oxide. Group: Biochemicals. Alternative Names: 1,2-1,2-Epoxycyclooctane; 9-9-Oxabicyclo[6. 1. 0]nonane. Grades: Highly Purified. CAS No. 286-62-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C8H14O. US Biological Life Sciences.
Worldwide
Cyclooctylamine
Cyclooctylamine. CAS No. 5452-37-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Cyclooctylamine
Cyclooctylamine. Group: Biochemicals. Alternative Names: Aminocyclooctane. Grades: Highly Purified. CAS No. 5452-37-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C8H15NH2. US Biological Life Sciences.
Worldwide
Cycloolivil
Cycloolivil isolated from the herbs of Maytenus hookeri Loes. Uses: Antioxidant. Synonyms: (1S)-1α-(3-Methoxy-4-hydroxyphenyl)-3,7-dihydroxy-6-methoxy-1,2,3,4-tetrahydronaphthalene-2β,3α-bismethanol; (2S)-2,3α-Bis(hydroxymethyl)-4β-(3-methoxy-4-hydroxyphenyl)-7-methoxytetralin-2α,6-diol. Grade: 0.98. CAS No. 3064-5-9. Molecular formula: C20H24O7. Mole weight: 376.4.
Cyclooxygenase 1 from Human, Recombinant
COX-1 catalyzes the conversion of arachidonic acid to prostaglandin H2 (the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins). It is involved in the homeostatic role of eicosanoids and constitutively almost all animal tissues. Has an apparent KM of 8.3 μM for arachidonic acid. Group: Enzymes. Synonyms: COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. COX-1. Mole weight: ~70 kDa. Activity: >20,000 units/mg. Stability: > 6 months. Storage: -80°C (as supplied); avoid freeze/thaw cycles by aliquoting protein. Form: 80 mM Tris, pH 8.0, containing 0.1% polysorbate 20, 300 uM DDC, and 10% glycerol. Source: Sf21 cells. Species: Human. COX-1; Constitutive cyclooxygenase; Prostaglandin H synthase 1; Prostaglandin endoperoxide synthase; EC 1.14.99.1; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: NATE-1237.
Cyclooxygenase 1, sheep
Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: COX-1. CAS No. 329967-85-3. Pack Sizes: 1 KU. Product ID: HY-E70229.
Cyclooxygenase 2 from Human, Recombinant
Cyclooxygenase 2 (COX-2) catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: The conversion fo arachidonic acid to PGH2. Discoveries of the induction of COX expression by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has become the focus of attention for the nonsteroidal anti-inflammatory drug (NSAID) development. Human recombinant COX-2 contains a six residue histidine sequence (His-tag) near the amino terminus. The His-tag enzyme, which has a Km value for arachidonate of 6.5 uM, exhibits enzyme activity and sensitivity to NSAIDs similar to the non-tagged enzyme. Group: Enzymes. Synonyms: Cyclooxygenase 2; Inducible Cyclooxygenase Prostaglandin H Synthase 2; COX-2. COX-2. Mole weight: 70 kDa. Activity: >8,000 U/mg. Stability: > 6 months. Storage: -80°C (as supplied). Source: Sf21 cells. Species: Human. Cyclooxygenase 2; Inducible Cyclooxygenase Prostaglandin H Synthase 2; COX-2. Cat No: NATE-1238.
Cyclooxygenase 2 from Ovine, Recombinant
Cyclooxygenase 2 (COX-2) catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: The conversion fo arachidonic acid to PGH2. Discoveries of the induction of COX expression by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has become the focus of attention for the nonsteroidal anti-inflammatory drug (NSAID) development. Human recombinant COX-2 contains a six residue histidine sequence (His-tag) near the amino terminus. The His-tag enzyme, which has a Km value for arachidonate of 6.5 uM, exhibits enzyme activity and sensitivity to NSAIDs similar to the non-tagged enzyme. Group: Enzymes. Synonyms: Cyclooxygenase 2; Inducible Cyclooxygenase Prostaglandin H Synthase 2; COX-2. Purity: >80% estimated by SDS-PAGE. COX-2. Mole weight: ~70 kDa. Activity: >20,000 U/mg. Stability: > 6 months. Storage: -80°C (as supplied). Source: Sf21 cells. Species: Ovine. Cyclooxygenase 2; Inducible Cyclooxygenase Prostaglandin H Synthase 2; COX-2. Cat No: NATE-1239.
Cyclopaldic acid
It is produced by the strain of Penicillum cyclopium var. album, Pen. cyclopium 77. Cyclopaldic acid of 2.5 μg/mL can inhibit the spore germination of Garlic botrytis spore 95%-100%. Synonyms: 3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-1,3-dihydro-2-benzofuran-4-carbaldehyde; 1,3-Dihydro-3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-4-isobenzofurancarboxaldehyde; Cyclopaldsaeure. CAS No. 477-99-6. Molecular formula: C11H10O6. Mole weight: 238.19.
Cyclopamine
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 11-Deoxojervine. CAS No. 4449-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17024.
Cyclopamine
Cyclopamine (11-deoxojervine) is a naturally occurring chemical that belongs to the group of steroidal jerveratrum alkaloids. It is a teratogen isolated from the corn lily (Veratrum californicum) that causes usually fatal birth defects. It can prevent the fetal brain from dividing into two lobes (holoprosencephaly) and cause the development of a single eye (cyclopia). It does so by inhibiting the hedgehog signaling pathway (Hh). Cyclopamine is useful in studying the role of Hh in normal development, and as a potential treatment for certain cancers in which Hh is overexpressed. Synonyms: HSDB-3505; HSDB 3505; HSDB-3505; 11-Deoxojervine. Grade: >98%. CAS No. 4449-51-8. Molecular formula: C27H41NO2. Mole weight: 411.62.
Cyclopamine
Cyclopamine antibacterial properties. Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched. Group: Biochemicals. Alternative Names: (2'R, 3S, 3'R, 3'aS, 6'S, 6aS, 6bS, 7'aR, 11aS, 11bR)-. Grades: Highly Purified. CAS No. 4449-51-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclopamine (11-Deoxojervine)
Cyclopamine (11-deoxojervine) is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells. Group: Inhibitors. Alternative Names: 11-deoxojervine. CAS No. 4449-51-8. Pack Sizes: 5mg. Product ID: S1146. Formula: C27H41NO2. Smiles: CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Cyclopamine tartrate
Cyclopamine tartrate. Alternative Names: (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-. CAS No. 1178510-81-0. Purity: 96%. Product ID: ACM1178510810. Molecular formula: C29H44NO5. Mole weight: 486.66. Alfa Chemistry - ISO 9001:32057 Certified.
Cyclopenin is one of an unusual family of benzodiazepine metabolites produced by a number of Penicllium species. Often mistakenly referred to as a mycotoxin, cyclopenin shows little toxicity against mammalian cells, bacteria or fungi in vitro. Cyclopenin is an intermediate in the biosynthesis of 3-O-methyl viridicatin, a strong inhibitor of the tumor necrosis factor alpha (TNF)-induced replication of human immunodeficiency virus (HIV). Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite. Group: Biochemicals. Grades: Highly Purified. CAS No. 19553-26-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclopenin
It is produced by the strain of Penicillum cyclopium and Pen. corymbiferum. Cyclopenin can inhibit the growth of plants. Cyclopenin acts as an inhibitor of acetylcholinesterase (AChE). Cyclopenin also has antibacterial activity against E. coli and M. pyogenes. Synonyms: (-)-Cyclopenine; (-)-Cyclopenin; Cyclopenine; (3S,3'R)-4-Methyl-3'-phenylspiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione; Spiro(3H-1,4-benzodiazepine-3,2'-oxirane)-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, cis-(-)-(9CI)-. Grade: ≥99%. CAS No. 20007-87-8. Molecular formula: C17H14N2O3. Mole weight: 294.30.