A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cyclothiazide is a positive allosteric modulator of ionotropic AMPA-type glutamate receptors. Cyclothiazide inhibits GABAA receptors. Cyclothiazide is frequently used to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current. Cyclothiazide can potentiate responses to kainate in hippocampal neurons. Cyclothiazide has effects on glutamatergic neurotransmission. Cyclothiazide also induces epileptiform EEG activity accompanying behavioral seizures[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101165.
Cyclothiazide
Cyclothiazide has been found to be a subunit-specific inhibitor of GABAC receptors and could be used as a diuretic agent as well as antihypertensive agent. Uses: Antihypertensive agents; diuretics, thiazide. Synonyms: 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide. Grade: ≥98% by HPLC. CAS No. 2259-96-3. Molecular formula: C14H16ClN3O4S2. Mole weight: 389.87.
Cyclothiazomycin
It is produced by the strain of Streptomyces sp. NR0516. It selectively inhibits renin activity and does not inhibit pepsin, aspartic acid, serine, mercaptan protease and metalloproteinases. In addition, it has weak antifungal activity. Synonyms: cyclothiazomycin A; 5102-II. CAS No. 133352-26-8. Molecular formula: C59H64N18O14S7. Mole weight: 1473.71.
Cyclothiocurvularin A
Cycuriocurvularin is a 12-membered macrolide isolated from Penicillium and Curvularia sp. Grade: >95% by HPLC. Molecular formula: C19H22O8S. Mole weight: 410.44.
Cyclotide C, partial
Cyclotide C, partial is isolated from Viola odorata. It has antimicrobial activity.
Cyclotide vibi-E
Cyclotide vibi-E is produced by Viola biflora. It probably participates in a plant defense mechanism. Cyclotide vibi-E has cytotoxic activity, active against a human lymphoma cell line with an IC50 of 3.2 μM.
Cyclotide vibi-H
Cyclotide vibi-H is produced by Viola biflora. It has antimicrobial and anticancer activity.
Cyclotraxin B
Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. It sometimes fused with tat-protein for increased brain permeability in rodent studies. It has been shown to exhibit putative anxiolytic properties in mice. It prevents cold allodynia induced by BDNF in mice and reduces cocaine self-administration. Synonyms: L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide. Grade: >98%. CAS No. 1203586-72-4. Molecular formula: C48H73N13O17S3. Mole weight: 1200.36.
Cyclotraxin B
Cyclotraxin B is a BBB-penetrable and selective TrkB inhibitor. Cyclotraxin B inhibits BDNF-induced TrkB activity in a non-competitive manner, with an IC50 of 0.30 nM. Cyclotraxin B has analgesic and anxiolytic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1203586-72-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1178.
Cyclotraxin B
Cyclotraxin B. Group: Biochemicals. Grades: Purified. CAS No. 1203586-72-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclotraxin B acetate
Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. Molecular formula: C50H77N13O19S3. Mole weight: 1260.42.
Cyclotriazadisulfonamide
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent way. Cyclotriazadisulfonamide is also a Sec61 translocon inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CADA. CAS No. 182316-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134809.
Cyclotriazadisulfonamide
Cyclotriazadisulfonamide is a CD4-targeted HIV entry inhibitor. CADA inhibits HIV at submicromolar levels by specifically down-modulating cell-surface and intracellular CD4. Synonyms: CADA; 9-benzyl-3-methylene-1,5-bis(p-tolylsulfonyl)-1,5,9-triazacyclododecane. Grade: >98%. CAS No. 182316-44-5. Molecular formula: C31H39N3O4S2. Mole weight: 581.79.
Cyclotrimethylenetriamine
Cyclotrimethylenetriamine. Alternative Names: CYCLOTRIMETHYLENETRIAMINE;HEXAHYDRO-S-TRIAZINE;HEXAHYDRO-SYM-TRIAZINE;hexahydro-1,3,5-triazine;Cyclotrimethylenetriamine50%aqueoussoln.;1,3,5-triazinane. CAS No. 110-90-7. Product ID: ACM110907. Molecular formula: C3H9N3. Mole weight: 87.12. Alfa Chemistry - ISO 9001:32057 Certified.
Cycloviolacin H2
Cycloviolacin H2 is produced by Viola hederacea. It probably participates in a plant defense mechanism.
Cycloviolacin H3
Cycloviolacin H3 is produced by Viola hederacea. It probably participates in a plant defense mechanism.
Cycloviolacin H4
Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Cycloviolacin H4 exhibits the most potent hemolytic activity in cyclotides reported so far, and this activity correlates with the size of a surface-exposed hydrophobic patch. Synonyms: cycloviolacin H4; CHEMBL499782. Molecular formula: C132H200N34O41S6. Mole weight: 3111.6.
Cycloviolacin O1
Cycloviolacin O1 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O13
Cycloviolacin O13 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O13 has hemolytic activity. Molecular formula: C133H207N37O38S6. Mole weight: 3124.67.
Cycloviolacin O14
Cycloviolacin O14 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O14 has hemolytic activity. Molecular formula: C132H197N35O41S6. Mole weight: 3122.57.
Cycloviolacin O15
Cycloviolacin O15 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O15 has hemolytic activity. Molecular formula: C130H195N33O39S6. Mole weight: 3036.52.
Cycloviolacin O16
Cycloviolacin O16 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O17
Cycloviolacin O17 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O18
Cycloviolacin O18 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O19
Cycloviolacin O19 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin-O2
Cycloviolacin-O2 is isolated from Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin-O2 has strong cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia and ovarian carcinoma cells. It also has weaker cytotoxic activity against normal lymphocytes and hemolytic activity. Synonyms: Cycloviolacin-O2; IHB9R8ET7W; CHEMBL4210529; cycloviolacin O2; 261714-23-2; Cyclo(Gly-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Trp-Ile-Pro-Cys-Ile-Ser-Ser-Ala-Ile-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Arg-Asn) 4->18,6->22, 11->27 trisdisulfide; UNII-IHB9R8ET7W; CHEMBL4285275; BDBM50452159. CAS No. 261714-23-2. Molecular formula: C133H207N37O39S6. Mole weight: 3140.7.
Cycloviolacin O20
Cycloviolacin O20 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O21
Cycloviolacin O21 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O22
Cycloviolacin O22 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O23
Cycloviolacin O23 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O24
Cycloviolacin O24 is produced by Viola odorata. It probably participates in a plant defense mechanism. Molecular formula: C126H179N35O42S6. Mole weight: 3048.36.
Cycloviolacin O25
Cycloviolacin O25 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O3
Cycloviolacin O3 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O8
Cycloviolacin O8 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin Y1
Cycloviolacin Y1 was found in Viola yedoensis. It has anti-HIV activity (EC50=1.2 microM). Synonyms: Cycloviolacin Y1. Molecular formula: C144H206N36O48S6. Mole weight: 3401.8.
Cycloviolacin Y2
Cycloviolacin Y2 was found in Viola philippica. It has antiviral activity.
Cycloviolacin Y3
Cycloviolacin Y3 was found in Viola philippica. It has antiviral activity.
Cycloviolacin Y4
Cycloviolacin Y4 was found in Viola yedoensis. It has anti-HIV activity (EC50=0.12 microM). Molecular formula: C127H202N32O41S6. Mole weight: 3025.53.
Cycloviolacin Y5
Cycloviolacin Y5 was found in Viola philippica. It has antiviral activity. Synonyms: Cycloviolacin Y5. Molecular formula: C132H209N33O42S6. Mole weight: 3122.7.
Cycloviolin-A
Cycloviolin-A is isolated from Leonia cymosa. It probably participates in a plant defense mechanism. Cycloviolin-A has anti-HIV activity. Molecular formula: C137H216N38O39S6. Mole weight: 3211.79.
Cycloviolin-B
Cycloviolin-B is isolated from Leonia cymosa. It probably participates in a plant defense mechanism. Cycloviolin-B has anti-HIV activity. Molecular formula: C120H177N31O40S6. Mole weight: 2886.26.
Cycloviolin-C
Cycloviolin-C is isolated from Leonia cymosa. It probably participates in a plant defense mechanism. Cycloviolin-C has anti-HIV activity. Molecular formula: C133H209N37O39S6. Mole weight: 3142.69.
Cycloviolin-D
Cycloviolin-D is isolated from Leonia cymosa. It probably participates in a plant defense mechanism. Cycloviolin-D has anti-HIV activity. Molecular formula: C135H205N37O38S6. Mole weight: 3146.68.
Cycloviracin B1
Cycloviracin B1 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. Synonyms: (1S,3R,8R,9S,10S,11S,12R,14R,19S,20S,21R,22S)-3-((16R)-16,22-bis(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)tricosyl)-14-(14-(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)-20-hydroxyhenicosyl)-9,10,11,20,21,22-hexahydroxy-2,6,13,17,23,24-hexaoxatricyclo[17.3.1.18,12]tetracosane-5,16-dione. CAS No. 142382-45-4. Molecular formula: C83H152O33. Mole weight: 1678.07.
Cycloviracin B2
Cycloviracin B2 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. CAS No. 142382-46-5. Molecular formula: C83H150O33. Mole weight: 1676.06.
Cyclovirobuxine D
Cyclovirobuxine D. Group: Biochemicals. Grades: Plant Grade. CAS No. 860-79-7. Pack Sizes: 20mg. Molecular Formula: C26H46N2O, Molecular Weight: 402.66. US Biological Life Sciences.
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1247879-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111653.
Cycoloy
Cycoloy.
CYD19
CYD19 is a potent Snail/HDAC dual target inhibitor. CYD19 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. CYD19 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Snail/HDAC-IN-1. CAS No. 2415281-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-144315.
CYD-4-61
CYD-4-61 is a novel Bax activator used for breast cancer research. CYD-4-61 inhibits triple-negative breast cancer MDA-MB-231 and ER-positive breast cancer MCF-7 cell lines proliferation. CYD-4-61 activates Bax protein to induce cytochrome c release and regulate apoptotic biomarkers, leading to cancer cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1425944-33-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148368.
Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 400882-07-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W663938.
Cyfluthrin is a class II Pyrethroid, with effects on the sodium current, especially late sodium current (INa-L). Uses: Insecticides. Synonyms: CYFLUTHRIN; Baythroid; beta-Cyfluthrin. CAS No. 68359-37-5. Molecular formula: C22H18Cl2FNO3. Mole weight: 434.29.
Cyfluthrin Phenoxy-d5
Cyfluthrin Phenoxy-d5 is the deuterized or labeled form of β-Cyfluthrin (C989510), which is a synthetic pyrethroid insectide and common household pesticide. It is highly toxic to fish, invertebrates, and insects, but it is far less toxic to humans. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H13D5Cl2FNO3, Molecular Weight: 439.32. US Biological Life Sciences.
Worldwide
CYH33 methanesulfonate
CYH33 methanesulfonate is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. CYH33 methanesulfonate has potent activity against solid tumors. Synonyms: CYH 33 methanesulfonate; Carbamic acid, N-(5-(6-((4-(methylsulfonyl)-1-piperazinyl)methyl)-4-(4-morpholinyl)pyrrolo(2,1-F)(1,2,4)triazin-2-yl)-4-(trifluoromethyl)-2-pyridinyl)-, methyl ester, methanesulfonate (1:1). CAS No. 1494684-33-1. Molecular formula: C25H33F3N8O8S2. Mole weight: 694.70.
Cyhalofop
Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at various growth stages in rice crop. Synonyms: Cyhalofop acid. Grade: >98%. CAS No. 122008-78-0. Molecular formula: C16H12FNO4. Mole weight: 301.27.
Cyhalofop-butyl
Cyhalofop-butyl is a post-emergence herbicide. Cyhalofop-butyl inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122008-85-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0861.
Cyhalofop Butyl
Cyhalofop Butyl. Group: Biochemicals. Alternative Names: Butyl (R) -2-[4- (4-Cyano-2-fluorophenoxy) phenoxy]propionate; (R) -2-[4- (4-Cyano-2-fluorophenoxy) phenoxy]propionic Acid Butyl Ester. Grades: Highly Purified. CAS No. 122008-85-9. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
Cyheptamide
An analogue of Carbamazepine. The toxicity of Cyheptamide in mice and rats is very low, and anticonvulsant activity is marked. Carbamazepine and Cyheptamide have certain stereochemical features in common with Phenytoin. Group: Biochemicals. Alternative Names: 10, 11-Dihydro-5H-dibenzo[a, d]cycloheptene-5-carboxamide; AY 8682; BS 7029; Carbamazepam; ICI 51426. Grades: Highly Purified. CAS No. 7199-29-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Cyheptamide
Cyheptamide is an analogue of Carbamazepine which is used in treatment of pain associated with trigeminal neuralgia. Synonyms: 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carboxamide; AY 8682; BS 7029; Carbamazepam; ICI 51426. CAS No. 7199-29-3. Molecular formula: C16H15NO. Mole weight: 237.30.
CYL-2
CYL-2 is a cyclic tetrapeptide produced by the strain of Cylindrocladium scoparium. It has anti-bacterial activity. Synonyms: (3s,6r,15as)-9-[(2s)-butan-2-yl]-6-(4-methoxybenzyl)-3-[6-(oxiran-2-yl)-6-oxohexyl]octahydro-2h-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3h,12h)-tetrone; Cyclo(O-methyltyrosine-L-isoleucine-L-pipecolic acid-2-amino-8-oxo-9,10-epoxydecanoic acid). CAS No. 42002-26-6. Molecular formula: C32H46N4O7. Mole weight: 598.73.
Cylindrol B is an extraordinary bioactive constituent sourced from nature manifesting unrivaled efficacy as an anti-neoplastic agent. By impeding intricate cellular mitosand stimulating programmed cell death, it exerts profound inhibitory influence on diverse cancerous cellular entities. Grade: ≥98% by HPLC. CAS No. 165187-16-6. Molecular formula: C23H30O4. Mole weight: 370.48.
Cylindrospermopsin
It is produced by the strain of Cylindrospermopsis raciborskii. Cylindrospermopsin is a tricyclic uracil derivative which is a cyanobacterial toxin. And it targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 μM, respectively), leading to cell death. It has been proved to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 μM. Synonyms: [2aS-[2aα,3α,4α,5aα,7β(S*)]]-6-[Hydroxy[2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; 6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; Cylindrospermopsine. Grade: ≥95%. CAS No. 143545-90-8. Molecular formula: C15H21N5O7S. Mole weight: 415.43.
Cylindrospermopsin
Cylindrospermopsin, a cyanotoxin, is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Cylindrospermopsin induces hepatocellular hypertrophy, renal cellular hypertrophy, intracellular reactive oxygen species (ROS), DNA strand breaks, mitochondrial hyperpolarisation, ultrastructural damage, and altered gene expression in liver, kidney, and intestinal cells. Cylindrospermopsin can be used in research including hepatocellular carcinoma and water quality testing[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143545-90-8. Pack Sizes: 50 μg; 100 μg; 500 μg. Product ID: HY-121360.
CYM2503
CYM2503 is a putative GalR2-positive allosteric modulator. CYM2503 increases the latency to first electrographic seizure and decreases the total time in seizure. CYM2503 also attenuates electroshock-induced seizures in mice. Galanin receptors type 1 (GalR1) and/or type 2 (GalR2) represent unique pharmacological targets for the research of seizures and epilepsy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1308833-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123671.