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Cyclosporine B. Group: Biochemicals. Alternative Names: Cyclosporin B, Ala2-cyclosporine, Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C61H109N11O12. US Biological Life Sciences.
Worldwide
Cyclosporine C
Cyclosporine C. Group: Biochemicals. Alternative Names: Cyclosporin C, Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C62H111N11O13. US Biological Life Sciences.
Worldwide
Cyclosporine Impurity 1
Cyclosporine Impurity 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4S,5R)-5-((R,E)-hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-8,10,13,17,23,26-hexamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide. Grade: ≥95%. Molecular formula: C57H101N11O12. Mole weight: 1132.50.
Cyclosporine Impurity 3 Sodium Salt
Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18.
Cyclosporine metabolite M17
Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-. Grade: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporine Resolution Mixture
This material is an approximate 100:1 (w/w) mixture of cyclosporine and cyclosporine U (USP).
Cyclosporin F
Cyclosporin F is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 6-((R-(E))-6,7-didehydro-N,4-dimethyl-L-2-aminooctanoic acid)-; Cyclo[L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-N-methyl-2-[(2R,4E)-2-methyl-4-hexenyl]-L-Gly-L-Abu-N-methyl-Gly-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-]. Grade: ≥95%. CAS No. 83574-28-1. Molecular formula: C62H111N11O11. Mole weight: 1186.61.
Cyclosporin G
Cyclosporin G is an active metabolite that can be produced from Tolypocladium inflatum. Cyclosporin G has immunosuppressive activity. Cyclosporin G inhibits proliferation of A431 cells[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 74436-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105023.
Cyclosporin H
Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin (HY-10219) or Prostaglandin E2 (HY-101952). Cyclosporin H lacks immunosuppressant activity of Cyclosporin A. Uses: Scientific research. Category: Signaling pathways. CAS No. 83602-39-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1122.
Cyclosporin H
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 83602-39-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin H
The minor analogues of the cyclosporin family have immunological activity because they do not bind to immunophilins. It is an inhibitor of phorbol ester that effectively promotes tumors on mouse skin, and effectively inhibits calcium/calmodulin-dependent phosphorylation of EF-2 in vitro. It is an effective and selective formyl peptide receptor antagonist and formyl peptide-induced superoxide formation inhibitor. Synonyms: 5-(N-methyl-D-valine)cyclosporine A. Grade: 95%. CAS No. 83602-39-5. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporin Impurity 10
Cyclosporin Impurity 10 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H109N11O11. Mole weight: 1184.62.
Cyclosporin Impurity 11
Cyclosporin Impurity 11 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-33-((R,E)-2-methylhex-4-en-1-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone. Molecular formula: C63H113N11O11. Mole weight: 1200.66.
Cyclosporin Impurity 12
Cyclosporin Impurity 12 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥95%. CAS No. 1907654-63-0. Molecular formula: C58H103N11O12. Mole weight: 1146.53.
Cyclosporin Impurity 13
Cyclosporin Impurity 13 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C25H29NO5. Mole weight: 423.51.
Cyclosporin Impurity 14
Cyclosporin Impurity 14 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-Oxazolidinecarboxylic acid, 3-methyl-5-(1-methyl-3-pentenyl)-2-oxo-, [4S-[4α,5β(1S*,3E)]]-; (4S,5R)-3-Methyl-5-((E)-(R)-1-methyl-pent-3-enyl)-2-oxo-oxazolidine-4-carboxylic acid; (4S,5R)-3-N-methyl-5-[((1R,3E)-1-methyl-3-penten)-1-yl]oxazolidin-2-one-4-carboxylic acid. CAS No. 81135-41-3. Molecular formula: C11H17NO4. Mole weight: 227.26.
Cyclosporin Impurity 2
Cyclosporin Impurity 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,E)-3,8-dihydroxy-4-methyl-2-(methylamino)oct-6-enoic acid. Grade: ≥90% by HPLC. Molecular formula: C10H19NO4. Mole weight: 217.26.
Cyclosporin Impurity 3 Sodium Salt
Cyclosporin Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-hydroxy-4-methyl-2-(methylamino)pentanoic acid, sodium salt (1:1). Grade: ≥95%. Molecular formula: C7H14NNaO3. Mole weight: 183.18.
Cyclosporin Impurity 4
Cyclosporin Impurity 4 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 4-(2E)-2-Buten-1-yl-2,4,5-trideoxy-2-(methylamino)-L-xylonic acid; (2S,3R,4R,E)-3-Hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid; 6-Octenoic acid, 3-hydroxy-4-methyl-2-(methylamino)-, (2S,3R,4R,6E). Grade: ≥90% by HPLC. CAS No. 59865-23-5. Molecular formula: C10H19NO3. Mole weight: 201.26.
Cyclosporin Impurity 4
Cyclosporin Impurity 4. Uses: For analytical and research use. CAS No. 59865-23-5. Molecular formula: C10H19NO3. Mole weight: 201.27. Catalog: APB59865235.
Cyclosporin Impurity 5
Cyclosporin Impurity 5. Uses: For analytical and research use. CAS No. 1907654-63-0. Molecular formula: C58H103N11O12. Mole weight: 1146.53. Catalog: APB1907654630.
Cyclosporin Impurity 6
Cyclosporin Impurity 6 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. CAS No. 1357559-31-3. Molecular formula: C8H15BF3N2K. Mole weight: 246.13.
Cyclosporin Impurity 7
Cyclosporin Impurity 7 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 6-[(2S,3R,4R,6E)-3-(acetyloxy)-8-bromo-4-methyl-2-(methylamino)-6-octenoic acid]-; (3R,4R)-N-Methyl-3-acetoxy-5-[(E)-3-bromo-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-); (1R,2R,E)-6-Bromo-1-((2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)-2-methylhex-4-en-1-yl acetate. Grade: ≥95%. CAS No. 138957-22-9. Molecular formula: C64H112BrN11O13. Mole weight: 1323.57.
Cyclosporin Impurity 8
Cyclosporin Impurity 8 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-Trimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-en-1-yl)silane; 1-(Trimethylsilyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1-propene; 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[(2E)-3-(trimethylsilyl)-2-propen-1-yl]-; Trimethyl[(1E)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-propen-1-yl]silane. Grade: ≥95%. CAS No. 79309-68-5. Molecular formula: C12H25BO2Si. Mole weight: 240.23.
Cyclosporin Impurity 9
Cyclosporin Impurity 9 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Molecular formula: C62H111N11O12. Mole weight: 1202.64.
Cyclosporin L
Cyclosporin L is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]. Grade: ≥95%. CAS No. 108027-39-0. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin L Related Compound 1
Cyclosporin L Related Compound 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(R)-2-Methyl-hex-4-enoic acid. Grade: ≥90% by HPLC. CAS No. 93553-73-2. Molecular formula: C7H12O2. Mole weight: 128.17.
Cyclosporin L Related Compound 2
Cyclosporin L Related Compound 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (R,E)-2-methylhex-4-en-1-ol; (E)-(R)-2-Methyl-hex-4-en-1-ol; (2R,4E)-2-Methyl-4-hexen-1-ol; 4-Hexen-1-ol, 2-methyl-, (2R,4E)-. Grade: ≥90% by HPLC. CAS No. 104372-56-7. Molecular formula: C7H14O. Mole weight: 114.18.
Cyclosporin L Related Compound 3
Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grade: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24.
Cyclosporin Q
Cyclosporin Q is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 9-L-valine-; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-L-valyl-L-valyl-N-methyl-L-leucyl]; 9-L-Valinecyclosporin A; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv. Grade: ≥95%. CAS No. 108027-42-5. Molecular formula: C60H107N11O12. Mole weight: 1174.58.
Cyclosporin T
Cyclosporin T is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-L-Leu-N-methyl-L-Val-); Cyclosporin A, 4-L-leucine-; 4-L-Leucinecyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]. Grade: ≥90% by HPLC. CAS No. 108027-44-7. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin U
Cyclosporin U is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Ciclosporin Impurity D; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucine]; [Leu11]Ciclosporin A; Ciclosporin U; Ciclosporin EP Impurity D; 11-L-Leucine-Cyclosporin A; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl); 11-L-Leucinecyclosporin A; Cyclosporine EP Impurity D; Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]. Grade: 95%. CAS No. 108027-45-8. Molecular formula: C61H109N11O12. Mole weight: 1188.61.
Cyclosporin V
Cyclosporin V is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Ciclosporin Impurity E; 1,11-Anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-(2S)-2-aminobutanoic acid]; [Abu1]Ciclosporin A; Ciclosporin V; Cyclosporine V; Ciclosporin EP Impurity E; Cyclosporin A, 1-[(2S)-2-aminobutanoic acid]-; 1-[(2S)-2-Aminobutanoic acid]cyclosporin A; cyclo[Abu-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Abu-Sar-N(Me)Leu-Val-N(Me)Leu]; cyclo[(N-(((2S)-2-aminobutyryl)-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl)-(2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; 1-(L-2-Aminobutanoic acid)cyclosporin A; Cyclo[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-2-aminobutanoyl]. Grade: ≥90% by HPLC. CAS No. 108027-46-9. Molecular formula: C63H113N11O12. Mole weight: 1216.63.
Cyclotetrakis(1,4-butylene Terephthalate)-d8 is labelled Cyclotetrakis(1,4-butylene terephthalate) (C989540) which is a cyclic trimer of poly(butylene terephthalate), a thermoplastic engineering polymer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C48H40D8O16, Molecular Weight: 888.93. US Biological Life Sciences.
Worldwide
Cyclothialidine
It is produced by the strain of Streptomyces filipinensis NR 0484. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.3 μmol/L, and the reference neomycin was 1.2 μmol/L. Synonyms: Cyclothialidine A; (2S)-2-[[(5S,8R)-5-[[(2S,3R)-1-(2-amino-3-hydroxypropanoyl)-3-hydroxypyrrolidine-2-carbonyl]amino]-13,15-dihydroxy-16-methyl-2,6-dioxo3-oxa-10-thia-7-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-8-carbonyl]amino]propanoic acid; N-[[(4R,7S)-1,3,4,5,6,7,8,10-octahydro-12,14-dihydroxy-7-[[(3R)-3-hydroxy-1-L-seryl-L-prolyl]amino]-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecin-4-yl]carbonyl]-L-alanine. CAS No. 147214-63-9. Molecular formula: C26H35N5O12S. Mole weight: 641.65.
Cyclothialidine B
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-76-1. Molecular formula: C25H33N5O11S. Mole weight: 611.62.
Cyclothialidine C
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 161161-54-2. Molecular formula: C26H35N5O11S. Mole weight: 625.66.
Cyclothialidine D
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-78-3. Molecular formula: C24H31N5O11S. Mole weight: 597.60.
Cyclothialidine E
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-79-4. Molecular formula: C25H33N5O11S. Mole weight: 611.63.
Cyclothiazide
Diuretic; antihypertensive. A subunit-specific inhibitor of GABAC receptors. Group: Biochemicals. Alternative Names: 3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide; Anhydron; Aquirel; Doburil; Fluidil; Lilly 35483; MDi 193; Renazide; Valmiran. Grades: Highly Purified. CAS No. 2259-96-3. Pack Sizes: 50mg. Molecular Formula: C??H??ClN?O?S?, Molecular Weight: 389.88. US Biological Life Sciences.
Worldwide
Cyclothiazide
Cyclothiazide has been found to be a subunit-specific inhibitor of GABAC receptors and could be used as a diuretic agent as well as antihypertensive agent. Uses: Antihypertensive agents; diuretics, thiazide. Synonyms: 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide. Grade: ≥98% by HPLC. CAS No. 2259-96-3. Molecular formula: C14H16ClN3O4S2. Mole weight: 389.87.
Cyclothiazide
Cyclothiazide is a positive allosteric modulator of ionotropic AMPA-type glutamate receptors. Cyclothiazide inhibits GABAA receptors. Cyclothiazide is frequently used to produce a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current. Cyclothiazide can potentiate responses to kainate in hippocampal neurons. Cyclothiazide has effects on glutamatergic neurotransmission. Cyclothiazide also induces epileptiform EEG activity accompanying behavioral seizures[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101165.
Cyclothiazomycin
It is produced by the strain of Streptomyces sp. NR0516. It selectively inhibits renin activity and does not inhibit pepsin, aspartic acid, serine, mercaptan protease and metalloproteinases. In addition, it has weak antifungal activity. Synonyms: cyclothiazomycin A; 5102-II. CAS No. 133352-26-8. Molecular formula: C59H64N18O14S7. Mole weight: 1473.71.
Cyclothiocurvularin A
Cycuriocurvularin is a 12-membered macrolide isolated from Penicillium and Curvularia sp. Grade: >95% by HPLC. Molecular formula: C19H22O8S. Mole weight: 410.44.
Cyclotide C, partial
Cyclotide C, partial is isolated from Viola odorata. It has antimicrobial activity.
Cyclotide vibi-E
Cyclotide vibi-E is produced by Viola biflora. It probably participates in a plant defense mechanism. Cyclotide vibi-E has cytotoxic activity, active against a human lymphoma cell line with an IC50 of 3.2 μM.
Cyclotide vibi-H
Cyclotide vibi-H is produced by Viola biflora. It has antimicrobial and anticancer activity.
Cyclotraxin B
Cyclotraxin B is a BBB-penetrable and selective TrkB inhibitor. Cyclotraxin B inhibits BDNF-induced TrkB activity in a non-competitive manner, with an IC50 of 0.30 nM. Cyclotraxin B has analgesic and anxiolytic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1203586-72-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1178.
Cyclotraxin B
Cyclotraxin B. Group: Biochemicals. Grades: Purified. CAS No. 1203586-72-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclotraxin B
Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. It sometimes fused with tat-protein for increased brain permeability in rodent studies. It has been shown to exhibit putative anxiolytic properties in mice. It prevents cold allodynia induced by BDNF in mice and reduces cocaine self-administration. Synonyms: L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide. Grade: >98%. CAS No. 1203586-72-4. Molecular formula: C48H73N13O17S3. Mole weight: 1200.36.
Cyclotraxin B acetate
Cyclotraxin B is a selective and potent Trk B (BDNF/NT-3) receptor inhibitor with an IC50 value of 0.30 nM. It prevents receptor activation by BDNF without interfering with BDNF binding. Molecular formula: C50H77N13O19S3. Mole weight: 1260.42.
Cyclotriazadisulfonamide
Cyclotriazadisulfonamide is a CD4-targeted HIV entry inhibitor. CADA inhibits HIV at submicromolar levels by specifically down-modulating cell-surface and intracellular CD4. Synonyms: CADA; 9-benzyl-3-methylene-1,5-bis(p-tolylsulfonyl)-1,5,9-triazacyclododecane. Grade: >98%. CAS No. 182316-44-5. Molecular formula: C31H39N3O4S2. Mole weight: 581.79.
Cyclotriazadisulfonamide
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent way. Cyclotriazadisulfonamide is also a Sec61 translocon inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CADA. CAS No. 182316-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134809.
Cyclotrimethylenetriamine
Cyclotrimethylenetriamine. Alternative Names: CYCLOTRIMETHYLENETRIAMINE;HEXAHYDRO-S-TRIAZINE;HEXAHYDRO-SYM-TRIAZINE;hexahydro-1,3,5-triazine;Cyclotrimethylenetriamine50%aqueoussoln.;1,3,5-triazinane. CAS No. 110-90-7. Product ID: ACM110907. Molecular formula: C3H9N3. Mole weight: 87.12. Alfa Chemistry - ISO 9001:32057 Certified.
Cycloviolacin H2
Cycloviolacin H2 is produced by Viola hederacea. It probably participates in a plant defense mechanism.
Cycloviolacin H3
Cycloviolacin H3 is produced by Viola hederacea. It probably participates in a plant defense mechanism.
Cycloviolacin H4
Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Cycloviolacin H4 exhibits the most potent hemolytic activity in cyclotides reported so far, and this activity correlates with the size of a surface-exposed hydrophobic patch. Synonyms: cycloviolacin H4; CHEMBL499782. Molecular formula: C132H200N34O41S6. Mole weight: 3111.6.
Cycloviolacin O1
Cycloviolacin O1 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O13
Cycloviolacin O13 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O13 has hemolytic activity. Molecular formula: C133H207N37O38S6. Mole weight: 3124.67.
Cycloviolacin O14
Cycloviolacin O14 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O14 has hemolytic activity. Molecular formula: C132H197N35O41S6. Mole weight: 3122.57.
Cycloviolacin O15
Cycloviolacin O15 is produced by Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin O15 has hemolytic activity. Molecular formula: C130H195N33O39S6. Mole weight: 3036.52.
Cycloviolacin O16
Cycloviolacin O16 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O17
Cycloviolacin O17 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O18
Cycloviolacin O18 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O19
Cycloviolacin O19 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin-O2
Cycloviolacin-O2 is isolated from Viola odorata. It probably participates in a plant defense mechanism. Cycloviolacin-O2 has strong cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia and ovarian carcinoma cells. It also has weaker cytotoxic activity against normal lymphocytes and hemolytic activity. Synonyms: Cycloviolacin-O2; IHB9R8ET7W; CHEMBL4210529; cycloviolacin O2; 261714-23-2; Cyclo(Gly-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Trp-Ile-Pro-Cys-Ile-Ser-Ser-Ala-Ile-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Arg-Asn) 4->18,6->22, 11->27 trisdisulfide; UNII-IHB9R8ET7W; CHEMBL4285275; BDBM50452159. CAS No. 261714-23-2. Molecular formula: C133H207N37O39S6. Mole weight: 3140.7.
Cycloviolacin O20
Cycloviolacin O20 is produced by Viola odorata. It probably participates in a plant defense mechanism.
Cycloviolacin O21
Cycloviolacin O21 is produced by Viola odorata. It probably participates in a plant defense mechanism.