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Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with IC50 of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. It has been used in the study of CaM binding, autophosphorylatio and dynamics. Synonyms: Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala; L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparagyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-threonyl-L-threonyl-L-methionyl-L-leucyl-L-alanine; CaM kinase II (290-309); Calmodulin-dependent Protein Kinase II fragment 290-309. Grade: ≥97% by HPLC. CAS No. 115044-69-4. Molecular formula: C103H185N31O24S. Mole weight: 2273.83.
Calmodulin-Dependent Protein Kinase II (290-309) trifluoroacetate salt
Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC50 value of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. Calmodulin-dependent protein kinase II (290-309) has been used in the study of CaM binding, autophosphorylation, and dynamics. Grade: ≥95%. Molecular formula: C103H185N31O24S·xCF3COOH. Mole weight: 2273.83.
Calmodulin-dependent Protein Kinase II fragment 290-309
Calmodulin-dependent Protein Kinase II fragment 290-309. Uses: For analytical and research use. CAS No. 115044-69-4. Mole weight: 2273.83. Catalog: AP115044694-B.
Calmodulin-dependent Protein Kinase II from Rat, Recombinant
Serine-threonine protein kinase:these kinases appear to be involved in neurotransmitter release, control of stimulus-induced gene expression, and in the phosphorylation of microtubule related proteins. Calmodulin-dependent protein kinase ii (camkII) is a serine/threonine kinase. it is a ca2+/calmodulin-dependent, truncated monomer (1-325 amino acid residues) of the α subunit. autophosphorylation of threonine 286 in the presence of ca2+ and calmodulin activates camkii and produces substantial ca2+/calmodulin-independent activity. Group: Enzymes. Synonyms: Calmodulin-dependent Protein Kinase II; 9026-43-1. Purity: > 95% determined by SDS-PAGE. Calmodulin-dependent Protein Kinase II. Mole weight: Apparent: 33 kDa Theoretical: 36 kDa. Activity: 5,000,000 units/mg. Storage: at -70°C. Avoid repeated freeze/thaw cycles. Form: 100 mM NaCl, 50 mM HEPES (pH 7.5 25°C), 0.1 mM EDTA, 1 mM DTT, 0.01% Brij 35 and 50% glycerol. Source: S. frugiperda Sf9. Species: Rat. Calmodulin-dependent Protein Kinase II; 9026-43-1; CaMKII. Cat No: NATE-1273.
calmodulin-lysine N-methyltransferase
One of a group of enzymes methylating proteins; see also EC 2.1.1.43 histone-lysine N-methyltransferase and EC 2.1.1.59 [cytochrome-c]-lysine N-methyltransferase. Group: Enzymes. Synonyms: S-adenosylmethionine:calmodulin (lysine) N-methyltransferase; S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.60. CAS No. 75603-20-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1962; calmodulin-lysine N-methyltransferase; EC 2.1.1.60; 75603-20-2; S-adenosylmethionine:calmodulin (lysine) N-methyltransferase; S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase. Cat No: EXWM-1962.
Caloporoside is a phospholipase C inhibitor produced by Caloporus dichrous. It has only weak antifungal and bacterial activity, and has the effect of selectively inhibiting phospholipase C. Synonyms: 2-O-Acetyl-5-O-(2-O-acetylhexopyranosyl)-2-C-[17-(2-carboxy-3-hydroxyphenyl)heptadecan-2-yl]hexonic acid; D-Mannonic acid, 5-O-(2-O-acetyl-beta-D-mannopyranosyl)-, 16-(2-carboxy-3-hydroxyphenyl)-1-methylhexadecyl ester, 2-acetate, (R)-. CAS No. 160471-36-3. Molecular formula: C40H64O17. Mole weight: 816.92.
Calotatug ginistinag
Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate targeting HER2, with an effective payload connected via a linker (LP, HY-148067) to a STING agonist (STING agonist-20, HY-148068), and has potential immune activation and anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMT-2056. CAS No. 2847102-44-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164919.
Caloxin 2A1
Caloxin 2A1 is a selective extracellular peptide inhibitor of the plasma membrane Ca2+-ATPase (PMCA). It has no effect on basic Mg2+-ATPase or Na+-K+-ATPase. Synonyms: H-Val-Ser-Asn-Ser-Asn-Trp-Pro-Ser-Phe-Pro-Ser-Ser-Gly-Gly-Gly-NH2; L-valyl-L-seryl-L-asparagyl-L-seryl-L-asparagyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-seryl-glycyl-glycyl-glycinamide; Glycinamide, L-valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycyl-. Grade: ≥95%. CAS No. 350670-85-8. Molecular formula: C64H91N19O22. Mole weight: 1478.54.
Caloxin 2A1
Caloxin 2A1 is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 350670-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3278.
Caloxin 2A1 TFA
Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. It does not affect basal Mg2+-ATPase or Na+-K+-ATPase. Molecular formula: C66H92F3N19O24. Mole weight: 1592.54.
CALP1
CALP1. Group: Biochemicals. Grades: Purified. CAS No. 145224-99-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CALP1
CALP1 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site and activating phosphodiesterase. CALP1 also binds to cytoplasmic sites on other Ca2+ channels such as NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). It was shown to suppress VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo. Synonyms: Calcium-like peptide 1. CAS No. 145224-99-3. Molecular formula: C40H75N9O10. Mole weight: 842.09.
CALP1 acetate
CALP1 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site and activating phosphodiesterase. CALP1 also binds to cytoplasmic sites on other Ca2+ channels such as NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). It was shown to suppress VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo. Synonyms: Calcium-like peptide 1 acetate. Molecular formula: C42H79N9O12. Mole weight: 902.13.
CALP1 TFA
CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 μM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity. Synonyms: L-valyl-L-alanyl-L-isoleucyl-L-threonyl-L-valyl-L-leucyl-L-valyl-L-lysine,trifluoroacetatesalt. Molecular formula: C42H76F3N9O12. Mole weight: 956.10.
CALP1 trifluoroacetate salt
CALP1 is an 8-residue calcium-like peptide that interacts with an EF hand motif based on the troponin C superfamily calcium binding site. CALP1 is also a cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site. CALP1 inhibits Ca2+-mediated cytotoxicity and apoptosis with IC50 of 52 μM and activates phosphodiesterase in the presence of calmodulin and absence of calcium. It also decreases radical production induced by phorbol 12-myristate 13-acetate in broncho-alveolar lavage cells. Synonyms: Calcium-like peptide 1. Grade: ≥95%. Molecular formula: C40H75N9O10·xCF3COOH. Mole weight: 842.08.
CALP2
CALP2. Group: Biochemicals. Grades: Purified. CAS No. 261969-04-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CALP2
CALP2 is a cell-permeable calmodulin (CaM) antagonist binding to the EF-hand/Ca2+-binding site. CALP2 exhibits an inhibitory effect on CaM-dependant phosphodiesterase activity, and leads to an increase on intracellular Ca2+ level by modulating Ca2+-channel activity. CALP2 was also shown to be a potent activator of alveolar macrophages. Synonyms: Calcium-like peptide 2. CAS No. 261969-04-4. Molecular formula: C68H104N14O13S. Mole weight: 1357.72.
CALP3
CALP3 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site. It activates phosphodiesterase in the absence of Ca2+ and suppresses Ca2+-mediated cytotoxicity and apoptosis (IC50 = 33 μM). Synonyms: Calcium-like peptide 3. CAS No. 261969-05-5. Molecular formula: C44H68N10O9. Mole weight: 881.08.
CALP3
CALP3. Group: Biochemicals. Grades: Purified. CAS No. 261969-05-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CALP3 acetate
CALP3 acetate is a potent Ca2+ channel blocker that mimics [Ca2+]i increase by regulating the activity of calmodulin (CaM), Ca2+ channels, and pumps. CALP3 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.CH3CO2H; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine acetic acid; CALP 3 acetate; CALP-3 acetate; Calcium-like peptide 3 acetate. Grade: ≥95%. Molecular formula: C46H72N10O11. Mole weight: 941.12.
CALP3 trifluoroacetate salt
CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons with IC50 of 37.25 μM. It also inhibits excitatory cytotoxicity with IC50 of 50.97 μM and apoptosis with IC50 of 33.41 μM. CALP3 was used to study as a new type of Ca2+ channel blocker that targets Ca2+ sensors and prevents Ca2+-mediated apoptosis. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.TFA; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine trifluoroacetate; CALP 3 trifluoroacetate; CALP-3 trifluoroacetate; CALP3 TFA; CALP 3 TFA; CALP-3 TFA; Calcium-like peptide 3 TFA. Grade: ≥98%. Molecular formula: C46H69F3N10O11. Mole weight: 995.11.
calpain-1
In peptidase family C2. Requires Ca2+ at micromolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.53, calpain-2. Group: Enzymes. Synonyms: μ-calpain; calcium-activated neutral protease I. Enzyme Commission Number: EC 3.4.22.52. CAS No. 78990-62-2. Calpain 1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4227; calpain-1; EC 3.4.22.52; 78990-62-2; μ-calpain; calcium-activated neutral protease I. Cat No: EXWM-4227.
calpain-2
Type example of peptidase family C2. Requires Ca2+ at millimolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.52, calpain-1. Group: Enzymes. Synonyms: calcium-activated neutral protease II; m-calpain; milli-calpain. Enzyme Commission Number: EC 3.4.22.53. CAS No. 702693-80-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4228; calpain-2; EC 3.4.22.53; 702693-80-9; calcium-activated neutral protease II; m-calpain; milli-calpain. Cat No: EXWM-4228.
Calpain-2-IN-1
Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with Kis of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of synaptic function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 144231-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145155.
calpain-3
This Ca2+-dependent enzyme is found in skeletal muscle and is genetically linked to limb girdle muscular dystrophy type 2A. The enzyme is activated by autoproteolytic cleavage of insertion sequence 1 (IS1),which allows substrates and inhibitors gain access to the active site. Substrates include the protein itself and connectin/titin. Belongs in peptidase family C2. Group: Enzymes. Synonyms: p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Enzyme Commission Number: EC 3.4.22.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4229; calpain-3; EC 3.4.22.54; p94; calpain p94; CAPN3; muscle calpain;calpain 3; calcium-activated neutral proteinase 3; muscle-specific calcium-activated neutral protease 3; CANP 3; calpain L3. Cat No: EXWM-4229.
Calpain inhibitor I
Calpain inhibitor I. Group: Biochemicals. Grades: Highly Purified. CAS No. 110044-82-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H37N3O4. US Biological Life Sciences.
Worldwide
Calpain Inhibitor I
MG-101, also known as Calpain Inhibitor I and ALLN, is a calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Activities of MG-101 includes: (1) reduce colon injury caused by dinitrobenzene sulphonic acid, (2) overcome acquired resistance to TRAIL, (3) protect against atractyloside-induced toxicity. (4). reduce colon injury caused by dinitrobenzene sulphonic acid. Synonyms: (S)-N-Acetyl-L-leucyl-N-(1-formylpentyl)-L-leucinamide; ALLN; ALLnL; CI-1 (peptide); Calp I; Calpain inhibitor I; MG 101; (S)-N-Acetyl-L-leucinyl-L-leucinyl-L-norleucinal; MG-101. Grade: 98 %. CAS No. 110044-82-1. Molecular formula: C20H37N3O4. Mole weight: 383.52.
Calpain Inhibitor II
Calpain inhibitor II is a cell-permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 600 pM). It inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Calpain inhibitor II can block nitric oxide production by interfering with transcription of the inducible nitric oxide synthase gene, which is a weak inhibitor of proteasome. It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems. Uses: Cysteine proteinase inhibitors. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-; L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-; N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide; ALLM; Calp II; CI 2; SUAM 312; N-acetylleucyl-leucyl-methioninal; Ac-Leu-Leu-Met-al; N-acetyl-L-leucyl-L-leucyl-L-methioninal. Grade: ≥98%. CAS No. 110115-07-6. Molecular formula: C19H35N3O4S. Mole weight: 401.57.
Calpain Inhibitor II
Calpain Inhibitor II. Group: Biochemicals. Grades: Highly Purified. CAS No. 110115-07-6. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Calpain Inhibitor III
Calpain Inhibitor III. Group: Biochemicals. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Calpain Inhibitor VI
Calpain Inhibitor VI is a cell-permeable peptide aldehyde which functions as a reversible calpain inhibitor. It is an inhibitor of the calcium-dependent cysteine proteases μ-calpain with IC50 of 7.5 nM for calpain-1 and m-calpain with IC50 of 78 nM for calpain-2. Calpain Inhibitor VI can reduce nuclear opacity and proteolysis of crystallins and α-spectrin. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Synonyms: SJA 6017. Grade: ≥95%. CAS No. 190274-53-4. Molecular formula: C17H25FN2O4S. Mole weight: 372.5.
Calpain Inhibitor XII
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Synonyms: Z-L-Nva-CONH-CH2-2-Py. Grade: ≥90%. CAS No. 181769-57-3. Molecular formula: C26H34N4O5. Mole weight: 482.6.
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Calpeptin attenuates apoptosis and intracellular inflammatory changes in muscle cells. Group: Inhibitors. CAS No. 117591-20-5. Pack Sizes: 10mg. Product ID: S7396. Formula: C20H30N2O4. Smiles: CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Calpeptin
Calpeptin. Group: Biochemicals. Grades: Purified. CAS No. 117591-20-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Synonyms: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grade: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Calpeptin
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets[1]. Calpeptin is also an inhibitor of cathepsin K[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117591-20-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100223.
Calphostin A
Calphostin A is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 120461-92-9. Molecular formula: C44H38O12. Mole weight: 758.76.
Calphostin B
Calphostin B is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 124824-06-2. Molecular formula: C37H34O11. Mole weight: 654.65.
Calphostin C
Calphostin C is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: UCN 1028 C, PKF 115-384. Grade: >95% by HPLC. CAS No. 121263-19-2. Molecular formula: C44H38O14. Mole weight: 790.76.
Calphostin C
Calphostin C is a highly selective PKC inhibitor (IC50=0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCN-1028C. CAS No. 121263-19-2. Pack Sizes: 100 μg. Product ID: HY-105416.
Calphostin C
0mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C44H38O14. CAS No. 121263-19-2. Prepack ID 33060444-0mg. Molecular Weight 790.76. See USA prepack pricing.
Calphostin C (Antibiotic UCN-1028 C, UCN 1028 C)
Calphostin C is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. It is a potent and specific inhibitor of protein kinase C with inhibition being light dependent. Also shown to inhibit cell proliferation and induce apoptosis in vitro. Group: Biochemicals. Alternative Names: Antibiotic UCN-1028 C, UCN 1028 C. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Calphostin D
Calphostin D is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: Phleichrome. CAS No. 124986-26-1. Molecular formula: C30H30O10. Mole weight: 550.55.
Calpurbatug
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRL1068. CAS No. 2635404-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990021.
Calreticulin Antibody [G16N21]
CRT. Group: Antibodies. Alternative Names: CRT, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60, CALR, CRTC. CAS No. Pack Sizes: 20uL. Product ID: F0472. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
Calteridol
Desgadolinium Gadoteridol is an impurity of Gadoteridol. Gadoteridol is a gadolinium-based MRI contrast agent. It is sold under the brand name ProHance. Synonyms: calteridol; CHEBI:37387; 1,4,7,10-Tetraazacyclododecane-1,4,7-triaceticacid,10-(2-hydroxypropyl)-; 2,2',2'-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic acid; ACMC-20mop4. Grade: 95%. CAS No. 120041-08-9. Molecular formula: C17H32N4O7. Mole weight: 404.46.
Calu-6 Transfection Reagent
Transfection Reagent for Calu6 Lewis Lung Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1728.
Nevada, Texas, USA
Calvatic acid
Calvatic acid is an antibiotic produced by Calvatia craniformis (Shw.) Fr. It has anti-gram-positive and negative bacteria (weak) activity, and inhibits Yoshida sarcoma and L-1210 cell activity. Synonyms: p-Carboxyphenylazoxycyanide; Benzoic acid, 4-(cyano-NNO-azoxy)-. CAS No. 54723-08-9. Molecular formula: C8H5N3O3. Mole weight: 191.14.
Calycanthine
Calycanthine. Group: Biochemicals. CAS No. 595-05-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CALYCANTHINE
Calycanthine is an alkaloid isolated from seeds of Chimonanthus praecox. Calycanthine exhibits potent antifungal activity against five plant pathogenic fungi including Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sclerotinia sderotiorum and Fusarium oxysportium. Synonyms: (1S,2R,10S,11R)-21,24-dimethyl-3,12,21,24-tetraazahexacyclo[9.7.3.3(2,10).0(1,10).0(4,9).0(13,18)]tetracosa-4,6,8,13,15,17-hexaene; (4bS,5R,10bS,11R)-13,18-dimethyl-5,6,11,12-tetrahydro-5,10b:11,4b-di(epiminoethano)dibenzo[c,h]-2,6-naphthyridine. Grade: >98%. CAS No. 595-05-1. Molecular formula: C22H26N4. Mole weight: 346.478.
Calycanthoside
Calycanthoside is a coumarin found in Eleutherococcus senticosus that exhibits anti-inflammatory and antibacterial effects. Synonyms: Isofraxidin 7-O-β-D-glucopyranoside; 6,8-Dimethoxy-7-(beta-D-glucopyranosyloxy)coumarin; 7-(beta-D-Glucopyranosyloxy)-6,8-dimethoxy-2H-1-benzopyran-2-one. Grade: 98.5%. CAS No. 483-91-0. Molecular formula: C17H20O10. Mole weight: 384.34.
Calyciphylline A isolated from the branch of Daphniphyllum macropodum Miq. Synonyms: Methyl (1R,2S,3R,5R,6S,8R,10S,16R,17R)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icos-13(19)-ene-17-carboxylate 8-oxide. Grade: 98.5%. CAS No. 596799-30-3. Molecular formula: C23H31NO4. Mole weight: 385.5.
Calycosin
Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cyclosin. CAS No. 20575-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0519.
Calycosin
Calycosin. Group: Biochemicals. Grades: Highly Purified. CAS No. 20575-57-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
CALYCOSIN
Pellitorine isolated from the herb of Astragalus membranaceus Bge. var. mongholicus. It may be an effective skin-lightening agent. Uses: Antineoplastic effects. Synonyms: 7,3'-DIHYDROXY-4'-METHOXYISOFLAVONE; 3'-HYDROXYFORMONONETIN; 3',7-DIHYDROXY-4'-METHOXYISOFLAVONE; 3-(3-Hydroxy-4-methoxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one; 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one. Grade: 0.99. CAS No. 20575-57-9. Molecular formula: C16H12O5. Mole weight: 284.26.
Calycosin 7-O- β-D-glucopyranoside
Calycosin 7-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 20633-67-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Calycosin 7-O-β-D-glucopyranoside
Calycosin-7-O-β-D-glucoside, a melanin biosynthesis inhibitor, is isolated from the methanol extract of astragalus. It showed scavenging activity to DPPH radicals. It is anticipated to be a promising anti-HIV agent. Synonyms: calycosin-7-O-beta-D-glucopyranoside; Calycosin 7-o-beta-D-glucoside; Calycosin-7-O-beta-D-glucoside; Calycosin 7-O-gluc. Grade: >98%. CAS No. 20633-67-4. Molecular formula: C22H22O10. Mole weight: 446.40.
Calycosin-7-O- β-D-glucoside
Calycosin-7-O- β-D-glucoside. Group: Biochemicals. Alternative Names: Calycosin-7-O- β-D-glucoside; Calycosin 7-glucoside. Grades: Plant Grade. CAS No. 20633-67-4. Pack Sizes: 20mg. Molecular Formula: C22H22O10, Molecular Weight: 446.404. US Biological Life Sciences.
Worldwide
Calyculin A
Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Calyculin A. CAS No. 101932-71-2. Pack Sizes: 10 μg. Product ID: HY-18983.
CALYCULIN A
Calyculin A is a effective inhibitor of the catalytic subunit of type-2A phosphatase as well as the type-1 phosphatase. IC50: 0.5 to 1 nM and 2 nM,respectively. It has lower IC50 value than okadaic acid which is a active blocker of phosphatase mentioned a. Uses: Calyculin a is a effective inhibitor of the catalytic subunit of type-2a phosphatase as well as the type-1 phosphatase. Synonyms: CALYCULIN A; CALYCULIN A, DISCODERMIA CALYX; calyculin A from discodermia calyx; CALYCULIN A FROM DISCODERMIA CALYX, 10 U G; N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentam; L-Ribonamide. Grade: >98 %. CAS No. 101932-71-2. Molecular formula: C50H81N4O15P. Mole weight: 1009.17.
Calystegine B2
Calystegine B2 is a bioactive compound known for its potential therapeutic properties in studying neurodegenerative diseases, such as Alzheimer's and Parkinson's. Extensive research has revealed its ability to inhibit enzymes involved in the progression of these diseases, making it a promising candidate for drug development. Synonyms: Nortropanoline; 8-Aza-bicyclo[3.2.1]octane-1,2,3,4-tetraol. CAS No. 127414-85-1. Molecular formula: C7H13NO4. Mole weight: 175.19.
Calyxamine B is a natural alkaloid found in the herbs of Salsola tetrandra. Synonyms: 1-(2,2,6,6-Tetramethyl-4-piperidinylidene)acetone. Grade: >98%. CAS No. 150710-72-8. Molecular formula: C12H21NO. Mole weight: 195.3.
CAM2602
CAM2602 is an orally active Aurora A-TPX2 protein-protein interaction inhibitor with a human Kd of 19 nM for Aurora A. CAM2602 increases the proportion of PH3 positive cells while reducing P-T288 Aurora A levels. CAM2602 arrests tumor xenograft growth in mice. CAM2602 can be used for the research of cancer, such as acute T cell leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056388-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168022.
CAM833
CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758364-02-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150147.
Camalexin
Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 135531-86-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119502.