A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Calpain Inhibitor VI is a cell-permeable peptide aldehyde which functions as a reversible calpain inhibitor. It is an inhibitor of the calcium-dependent cysteine proteases μ-calpain with IC50 of 7.5 nM for calpain-1 and m-calpain with IC50 of 78 nM for calpain-2. Calpain Inhibitor VI can reduce nuclear opacity and proteolysis of crystallins and α-spectrin. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Synonyms: SJA 6017. Grades: ≥95%. CAS No. 190274-53-4. Molecular formula: C17H25FN2O4S. Mole weight: 372.5.
Calpain inhibitor vii
Heterocyclic Organic Compound. Alternative Names: CALPAIN INHIBITOR VII;LLPCK, HCL;Llpck,hydrochloride. CAS No. 100241-76-7. Molecular formula: C22H34ClN3O3. Mole weight: 423.98. Catalog: ACM100241767.
Calpain Inhibitor XII
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Synonyms: Z-L-Nva-CONH-CH2-2-Py. Grades: ≥90%. CAS No. 181769-57-3. Molecular formula: C26H34N4O5. Mole weight: 482.6.
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Synonyms: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grades: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Calpeptin
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID 50 of 40 nM for Calpain I in human platelets [1]. Calpeptin is also an inhibitor of cathepsin K [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 117591-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100223.
Calpeptin
Calpeptin. Group: Biochemicals. Grades: Purified. CAS No. 117591-20-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Calphostin A
Calphostin A is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 120461-92-9. Molecular formula: C44H38O12. Mole weight: 758.76.
Calphostin B
Calphostin B is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 124824-06-2. Molecular formula: C37H34O11. Mole weight: 654.65.
Calphostin C
Calphostin C is a highly selective PKC inhibitor ( IC 50 =0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCN-1028C. CAS No. 121263-19-2. Pack Sizes: 100 μg. Product ID: HY-105416.
Calphostin C
0mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C44H38O14. CAS No. 121263-19-2. Prepack ID 33060444-0mg. Molecular Weight 790.76. See USA prepack pricing.
Calphostin C
Calphostin C is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: UCN 1028 C, PKF 115-384. Grades: >95% by HPLC. CAS No. 121263-19-2. Molecular formula: C44H38O14. Mole weight: 790.76.
Calphostin C (Antibiotic UCN-1028 C, UCN 1028 C)
Calphostin C is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. It is a potent and specific inhibitor of protein kinase C with inhibition being light dependent. Also shown to inhibit cell proliferation and induce apoptosis in vitro. Group: Biochemicals. Alternative Names: Antibiotic UCN-1028 C, UCN 1028 C. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Calphostin C (UCN 1028C, PKF115-584, Cal-C)
Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source:Cladosporium cladosporioides sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C44H38O14 , Molecular Weight: ~790.8. US Biological Life Sciences.
Worldwide
Calphostin D
Calphostin D is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: Phleichrome. CAS No. 124986-26-1. Molecular formula: C30H30O10. Mole weight: 550.55.
Calpinactam
Specific anti-mycobacterial. Inhibits growth of Mycobacteria smegmatis but also Mycobacteria tuberculosis. M. smegmatis is used as a model for mycobacterial species. It is useful for the research analysis of other Mycobacteria species in laboratory experiments. M. smegmatis is commonly used in work on the mycobacterium species, since it is a "fast grower" and non-pathogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1205538-83-5. Pack Sizes: 250ug, 1mg. Molecular Formula: C38H57N9O8. US Biological Life Sciences.
Worldwide
Calteridol
Desgadolinium Gadoteridol is an impurity of Gadoteridol. Gadoteridol is a gadolinium-based MRI contrast agent. It is sold under the brand name ProHance. Synonyms: calteridol; CHEBI:37387; 1,4,7,10-Tetraazacyclododecane-1,4,7-triaceticacid,10-(2-hydroxypropyl)-; 2,2',2'-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic acid; ACMC-20mop4. Grades: 95%. CAS No. 120041-08-9. Molecular formula: C17H32N4O7. Mole weight: 404.46.
Calu-6 Transfection Reagent
Transfection Reagent for Calu6 Lewis Lung Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1728.
Nevada, Texas, USA
Calvatic acid
Calvatic acid is an antibiotic produced by Calvatia craniformis (Shw.) Fr. It has anti-gram-positive and negative bacteria (weak) activity, and inhibits Yoshida sarcoma and L-1210 cell activity. Synonyms: p-Carboxyphenylazoxycyanide; Benzoic acid, 4-(cyano-NNO-azoxy)-. CAS No. 54723-08-9. Molecular formula: C8H5N3O3. Mole weight: 191.14.
Calvulanic acid
Calvulanic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 58001-44-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H9NO5. US Biological Life Sciences.
Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclosin. CAS No. 20575-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0519.
Calycosin
Pellitorine isolated from the herb of Astragalus membranaceus Bge. var. mongholicus. It may be an effective skin-lightening agent. Uses: Antineoplastic effects. Synonyms: 7,3'-DIHYDROXY-4'-METHOXYISOFLAVONE;3'-HYDROXYFORMONONETIN;3',7-DIHYDROXY-4'-METHOXYISOFLAVONE;3-(3-Hydroxy-4-methoxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one;7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one. Grades: 0.99. CAS No. 20575-57-9. Molecular formula: C16H12O5. Mole weight: 284.26.
Calycosin
Calycosin. Group: Biochemicals. Grades: Highly Purified. CAS No. 20575-57-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
Calycosin-7-glucoside
Calycosin-7-glucoside. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20633-67-4. Molecular Formula: C22H22O10. Mole Weight: 446.41. Catalog: APB20633674.
Calycosin 7-O- β-D-glucopyranoside
Calycosin 7-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 20633-67-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Calycosin-7-O- β-D-glucoside
Calycosin-7-O- β-D-glucoside. Group: Biochemicals. Alternative Names: Calycosin-7-O- β-D-glucoside; Calycosin 7-glucoside. Grades: Plant Grade. CAS No. 20633-67-4. Pack Sizes: 20mg. Molecular Formula: C22H22O10, Molecular Weight: 446.404. US Biological Life Sciences.
Worldwide
CALYCULIN A
Calyculin A is a effective inhibitor of the catalytic subunit of type-2A phosphatase as well as the type-1 phosphatase. IC50: 0.5 to 1 nM and 2 nM,respectively. It has lower IC50 value than okadaic acid which is a active blocker of phosphatase mentioned a. Uses: Calyculin a is a effective inhibitor of the catalytic subunit of type-2a phosphatase as well as the type-1 phosphatase. Synonyms: CALYCULIN A;CALYCULIN A, DISCODERMIA CALYX;calyculin A from discodermia calyx;CALYCULIN A FROM DISCODERMIA CALYX, 10 U G;N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentam;L-Ribonamide. Grades: >98 %. CAS No. 101932-71-2. Molecular formula: C50H81N4O15P. Mole weight: 1009.17.
Calystegine A3
Calystegine A3, a biomedically significant natural compound, displays remarkable potency in extensive biomedical research. Its distinct characteristics have been duly recognized for studying specific neurologic ailments, including the renowned Alzheimer's disease. Through meticulous analysis, Calystegine A3 is particularly noteworthy for its pronounced inhibitory properties targeting crucial enzymes associated with the development of neurodegenerative conditions. Synonyms: [1R-(2-endo,3-exo)]-8-Azabicyclo[3.2.1]octane-1,2,3-triol; Calystegin A3; (+)-Calystegine A3; 8-Azabicyclo[3.2.1]octane-1,2,3-triol, (1R,2S,3R,5R)-. Grades: ≥95%. CAS No. 131580-36-4. Molecular formula: C7H13NO3. Mole weight: 159.18.
Calystegine A5
Calystegine A5 is an extraordinary natural alkaloid obtained from diverse botanical sources, exhibiting remarkable potency in the suppression of glycosidases. This outstanding attribute renders Calystegine A5 a highly promising tool for the research of Type 2 diabetes. Synonyms: Calystegine A5; Calystegin A5; 165905-26-0; (1R,3S,4S,5R)-8-AZABICYCLO[3.2.1]OCTANE-1,3,4-TRIOL; 8-Azabicyclo(3.2.1)octane-1,3,4-triol, (1R,3S,4S,5R)-; CHEMBL3233943; AKOS040735614. CAS No. 165905-26-0. Molecular formula: C7H13NO3. Mole weight: 159.18.
Calystegine B1
Calystegine B1 is an exceedingly powerful naturally occurring alkaloid, garnering immense attention for its prowess in obstructing diverse enzymes. This compound has proven instrumental in studying an array of afflictions like cancer, neurodegenerative pathologies as well as viral invasions. Synonyms: Calystegine B1; 127414-86-2; (1R,2S,3R,5S,6R)-8-AZABICYCLO[3.2.1]OCTANE-1,2,3,6-TETROL; Calystegine B(1); 8-azabicyclo[3.2.1]octane-1,2,3,6-tetrol; DTXSID20925887; AKOS040736062; FS-6673; 8-Azabicyclo(3.2.1)octane-1,2,3,6-tetrol, (1R,2S,3R,5S,6R)-rel-. CAS No. 127414-86-2. Molecular formula: C7H13NO4. Mole weight: 175.18.
Calystegine B2
Calystegine B2 is a bioactive compound known for its potential therapeutic properties in studying neurodegenerative diseases, such as Alzheimer's and Parkinson's. Extensive research has revealed its ability to inhibit enzymes involved in the progression of these diseases, making it a promising candidate for drug development. Synonyms: (1R,2S,3R,4S,5R)-8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol; Nortropanoline. CAS No. 127414-85-1. Molecular formula: C7H13NO4. Mole weight: 175.19.
Calystegine B3
Calystegine B3 is a highly potent natural inhibitor with widespread application encompassing the extensive research in targeting the debilitating neurodegenerative conditions, namely Alzheimer's and Parkinson's diseases. Synonyms: 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (1R,2R,3R,4S,5R)-; 2-Epicalystegine B2; (+)-Calystegine B3; (1R,5R)-8-Azabicyclo[3.2.1]octane-1,2alpha,3alpha,4beta-tetrol; Calystegin B3; 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (2-exo,3-exo,4-endo)-(+)-. Grades: >98%. CAS No. 178231-95-3. Molecular formula: C7H13NO4. Mole weight: 175.19.
Calystegine B4
Calystegine B4 is a potent natural compound found in various plants exhibiting promising applications in the study of neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: Calystegine B4; 184046-85-3; (1R,2S,3R,4R,5R)-8-azabicyclo[3.2.1]octane-1,2,3,4-tetrol; CHEMBL3233945; 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (1R,2S,3R,4R,5R)-; 8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol, (1R,2S,3R,4R,5R)-; (-)-Calystegine B4; Q29YLG74LW; Calystegine B4 - 90% min; DTXSID501317306; BDBM50002909; 8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol, (2-endo,3-exo,4-exo)-(-)-. CAS No. 184046-85-3. Molecular formula: C7H13NO4. Mole weight: 175.18.
Calystegine N1
Calystegine N1 is a highly potent inhibitor assuming a pivotal and indispensable function in the research of diverse ailments including cancer, viral infections and neurodegenerative afflictions.
CAM2602
CAM2602 is an Aurora A-TPX2 interaction inhibitor that has a binding affinity of 19 nM to Aurora A. CAM2602 can inhibit the growth of pancreatic cancer cells. In solid tumor transplant models, CAM2602 can increase the proportion of PH3 positive cells while reducing the proportion of P-Thr288 Aurora A positive cells, thereby inhibiting tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3056388-47-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168022.
Camalexin
Camalexin is an indole phytoalexin Camelina sativa and Arabidopsis (Cruciferae), exhibiting antibacterial, antifungal, antiproliferative and anticancer activities. Uses: Anti-infective agents. Synonyms: 3-(1,3-thiazol-2-yl)-1H-indole; 3-(thiazol-2-yl)indole. Grades: 98%. CAS No. 135531-86-1. Molecular formula: C11H8N2S. Mole weight: 200.26.
Camalexin
Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 135531-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119502.
Camazepam
Camazepam. Group: Biochemicals. Alternative Names: N,N-Dimethylcarbamic acid 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl ester; (+/-)-Camazepam; Albego. Grades: Highly Purified. CAS No. 36104-80-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H18ClN3O3. US Biological Life Sciences.
Worldwide
Cambendazole
Cambendazole is one of the most effective agents for the research of human strongyloidiasis and [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26097-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107483.
Camelliaside A, a flavonoid found in C. sinensis, has radical scavenging and enzyme inhibitory activities. Synonyms: 4H-1-Benzopyran-4-one, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1?6)-O-[β-D-galactopyranosyl-(1?2)]-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 3-[(O-6-Deoxy-α-L-mannopyranosyl-(1?6)-O-[β-D-galactopyranosyl-(1?2)]-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Kaempferol-3-O-[2-O-β-D-galactose-6-O-α-L-rhamnose]-β-D-glucoside; 3-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one. Grades: 98%. CAS No. 135095-52-2. Molecular formula: C33H40O20. Mole weight: 756.66.
Camelliaside A
Camelliaside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 135095-52-2. Pack Sizes: 10mg. Molecular Formula: C33H40O20, Molecular Weight: 756.66. US Biological Life Sciences.
Worldwide
Camelliaside B
Camelliaside B is a flavonol triglycoside isolated from seeds of Camellia sinensis. Synonyms: Camelliaside B; 131573-90-5; CamelliasideB; 3-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; CHEMBL501769; CHEBI:183907; LLPRITPJQPQXIR-BVDHFOMSSA-N; HY-N2605; AKOS040756498; MS-31251; CS-0023008; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one. CAS No. 131573-90-5. Molecular formula: C32H38O19. Mole weight: 726.63.
Camelliaside B
Camelliaside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 131573-90-5. Pack Sizes: 10mg. Molecular Formula: C32H38O19, Molecular Weight: 726.63. US Biological Life Sciences.
Worldwide
camelliol C synthase
The product is 97% camelliol, 2% achilleol A and 0.2% β-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC 5.4.99.39, β-amyrin synthase. Group: Enzymes. Synonyms: CAMS1; LUP3 (gene name). Enzyme Commission Number: EC 5.4.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5579; camelliol C synthase; EC 5.4.99.38; CAMS1; LUP3 (gene name). Cat No: EXWM-5579.
Camibirstat
FHD-286 is a selective, oral inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor. FHD-286 has the potential for the research of BAF (BRG1/BRM-associated factor)-related disorders such as acute myeloid leukemia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FHD-286. CAS No. 2671128-05-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144835.
Camidanlumab
Camidanlumab (HuMax-TAC) is a CD25 monoclonal antibody. Camidanlumab targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including lymphoma and leukemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuMax-TAC. CAS No. 921618-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99233.
Camidanlumab
Camidanlumab is a monoclonal antibody targeting CD25, which is expressed on activated T cells. Camidanlumab can be used in the synthesis of ADC Camidanlumab tesirine, which is investigated for the treatment of lymphoma and leukemia. Synonyms: HuMax-TAC. CAS No. 921618-45-3.
CAM-IN-1
A potent and selective inhibitor of E-selectin (IC50= 7 nM) and ICAM-1 (IC50= 5 nM). Synonyms: Thieno[2,3-c]pyridine-2-carboxamide, 4-(4-bromophenoxy)-N-methyl-. CAS No. 251994-14-6. Molecular formula: C15H11BrN2O2S. Mole weight: 363.23.
Camizestrant
Camizestrant is an orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Synonyms: N-[1-(3-fluoropropyl)azetidin-3-yl]-6-[(6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl]pyridin-3-amine; Estrogen receptor antagonist 2; AZD-9833; AZD 9833; AZD9833; NSC-828717; N-[1-(3-Fluoropropyl)-3-azetidinyl]-6-[(6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl]-3-pyridinamine. Grades: ≥98%. CAS No. 2222844-89-3. Molecular formula: C24H28F4N6. Mole weight: 476.51.
Camizestrant
Camizestrant (AZD-9833) is a potent and orally active estrogen receptor (ER) antagonist. Camizestrant is used for the study of ER + HER2-advanced breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9833. CAS No. 2222844-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136255.
CaMKII-IN-1
CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. Synonyms: CaMKII-IN-1; CaMKII; CaMKII IN-1; CaMKII IN 1; CaMKII-IN 1. Grades: >98%. CAS No. 1208123-85-6. Molecular formula: C29H30ClN5O2S. Mole weight: 548.1.
CaMKII Inhibitor XII (Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor XII)
A pyrimidinyl sulfonamide compound that acts as a potent, reversible and CaM non-competitive inhibitor of CaMKII activities (IC50 = 0.063uM) with excellent selectivity over several kinases (IC50 = >60, 36, 11, 30 and 21uM for CaMKIV, MLCK, p38alpha, Akt1 and PKC, respectively). Shown to exhibit ~25-fold greater potency towards CaMKII than the CaM-competitive inhibitor KN-93. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CaMKP inhibitor sodium
CaMKP inhibitor sodium (compound 5) is an inhibitor of Ca 2+ /neutral protein-dependent protein concentration (CaMKP) and its nuclear type (CaMKP-N) (IC50: 6.4 μM, CaMKP; 6.6 μM, CaMKP-N). CaMKP is one type of Ser/Thr protein, which can be passed through to remove the oxidized oxidized protein (CaMK). CaMKP inhibitor sodium inhibits CaMKP mediated phospho-CaMKI hydrolysis, unaffectes protein phosphoric acid 2C (PP2C) and calcineurin (CaN) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52789-62-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11000A.
Camlipixant
Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC 50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-5937. CAS No. 1621164-74-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136026.