A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Camp sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-001-030-848, Adenosine-3 ,5 -Monophosphoric Acid, adenosine-3,5-cyclic-monophosphate, X-063151, 37839-81-9. Product Category: Heterocyclic Organic Compound. Appearance: white powder. CAS No. 37839-81-9. Molecular formula: C10H11N5NaO6P. Mole weight: 351.19. Purity: >98.0%(LC). IUPACName: sodium 8-(6-aminopurin-9-yl)-3-oxido-3-oxo-2,4,7-trioxa-3$l^{5}-phosphabicyclo[4.3.0]nonan-9-ol. Canonical SMILES: C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)[O-].[Na+]. Product ID: ACM37839819. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cyclic AMP sodium.
cAMPS-Rp, triethylammonium salt
cAMPS-Rp, triethylammonium salt. Group: Biochemicals. Grades: Purified. CAS No. 151837-09-1. Pack Sizes: 1mg. US Biological Life Sciences.
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cAMPS-Sp, triethylammonium salt
cAMPS-Sp, triethylammonium salt. Group: Biochemicals. Grades: Purified. CAS No. 93602-66-5. Pack Sizes: 1mg. US Biological Life Sciences.
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Camptothecin
Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC 50 of 679 nM [1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Campathecin; (S)-(+)-Camptothecin; CPT. CAS No. 7689-3-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-16560.
Camptothecin
Camptothecin - Product ID: NST-10-81. Category: Alkaloids. Purity: 98%. Test method: HPLC. CAS No. 7689-3-4. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: Yellow to brown Powder. Molecular formula: C20H16N2O4. Mole weight: 348.35. Storage: +2 +8 °C.
Camptothecin
It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an antineoplastic agent, a genotoxin and a plant metabolite. It is a pyranoindolizinoquinoline, a tertiary alcohol, a delta-lactone and a quinoline alkaloid. Alternative Names: Camptothecine. (S)-(+)-Camptothecin. Campathecin. CAS No. 7689-3-4. Product ID: PIPE-0600. Molecular formula: C20H16N2O4. Mole weight: 348.4. EINECS: 444-280-6. SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O. Appearance: Cryst. Category: Natural Extract.
Camptothecin
Camptothecin. Group: Biochemicals. Alternative Names: (S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione; Camptothecine. Grades: Highly Purified. CAS No. 7689-3-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C20H16N2O4. US Biological Life Sciences.
Worldwide
Camptothecin
Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-(+)-Camptothecin. Product Category: Inhibitors. CAS No. 7689-3-4. Mole weight: 348.4. Purity: 98%+. Product ID: ACM7689034. Alfa Chemistry ISO 9001:2015 Certified.
Camptothecin
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231. Camptothecin is extratced from the barks of Camptotheca acuminata Decne. It can be used in cosmetics material. It is also an impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Uses: Adcs cytotoxin. Synonyms: camptothecin; 7689-03-4; Camptothecine; (S)-(+)-Camptothecin; Campathecin; (+)-Camptothecin; (+)-Camptothecine; d-Camptothecin; 20(S)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; Camptothecine (S,+); CHEMBL65; (S)-4-ethyl-4-hydroxy-1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-94600; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinol. Grade: >98%. CAS No. 7689-3-4. Molecular formula: C6H14N2O2.ClH. Mole weight: 182.65.
Camptothecin, 10-Hydroxy-, Camptotheca acuminata - CAS 64439-81-2
A cell-permeable powerful DNA topoisomerase I inhibitor. Group: Fluorescence/luminescence spectroscopy.
Camptothecin 1-oxide
Camptothecin 1-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: camptothecin-1-oxide; Baicalin std.; d-Camptothecin; camptothecin-N-oxide; CAMPTOTHECINE; CaMpathecin; CAMPTOTHECIN; Camptohecin. Product Category: Heterocyclic Organic Compound. CAS No. 86639-48-7. Molecular formula: C20H16N2O5. Mole weight: 364.35144;g/mol. Purity: 0.96. IUPACName: 1H-Pyrano[3,4_6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)- dione, 4-. Canonical SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5[N+](=C4C3=C2)[O-])O. Density: 1.55g/cm³. Product ID: ACM86639487. Alfa Chemistry ISO 9001:2015 Certified.
Camptothecin-20(S)-O-propionate
Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-&Lota; inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Camptothecin-20-O-propionate. CAS No. 194414-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114668.
Camptothecin, Camptotheca acuminata - CAS 2114454
A cell-permeable DNA topoisomerase I inhibitor. Group: Fluorescence/luminescence spectroscopy.
Camptothecin sodium
An alkaloid topoisomerase I (topo I) inhibitor with anticancer properties. It is isolated from camptotheca acuminata, a deciduous tree or nothapodytes foetida. Synonyms: 20(S)-Camptothecin Sodium Salt; Camptothecine Sodium; NSC 100880; Sodium Camptothecin; (αS)-α-ethyl-9,11-Dihydro-α-hydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid Monosodium Salt; 21,22-Secocamptothecin-21-oic Acid Monosodium Salt. Grade: ≥95%. CAS No. 25387-67-1. Molecular formula: C20H17N2NaO5. Mole weight: 388.35.
Camrelizumab
Camrelizumab is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. Camrelizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities. Synonyms: Immunoglobulin G4, anti-(cell surface receptor) (human-Mus musculus monoclonal SHR-1210 heavy chain), disulfide with human-Mus musculus monoclonal SHR-1210 light chain, dimer; AiRuiKa; HR 301210; Immunoglobulin G4, anti-(human programmed cell death protein 1) (human-Mus musculus monoclonal SHR-1210 heavy chain), disulfide with human-Mus musculus monoclonal SHR-1210 light chain, dimer; INCSHR 01210; INCSHR 1210; INCSHR01210; SHR 1210. Grade: ≥98%. CAS No. 1798286-48-2.
Camrelizumab
Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC 50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHR-1210. CAS No. 1798286-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9971.
Camstatin
Camstatin, an analog of PEP-19, has been found to have enhanced activities binding to and antagonism of calmodulin. Synonyms: Camstatin; 1002295-95-5; AKOS024458712; PD078973; S-1002295-95-5. Grade: ≥95% by HPLC. CAS No. 1002295-95-5. Molecular formula: C122H203N39O34. Mole weight: 2760.19.
Camu Camu Extract
Camu Camu Extract. Applications: Used for functional drinks, medicines, health products, cosmetics and so on. Group: Others. Synonyms: Camu Camu Extract; Myrciaria dubia. Purity: 20% Vitamin C HPLC. Appearance: Light yellow brown powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Myrciaria dubia. Camu Camu Extract; Myrciaria dubia; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-153.
Camu powder
The main beneficial substances contained in Acai include polyphenols, flavonoids, anthocyanins and mostly original anthocyanin classes. Acai's dark purple pericarp contain anthocyanins of red wine is a lot of times, there is a potent antioxidant, containing Omega 6 (linoleic acid) and Omega 9 (oleic acid) of these two essential fatty acids. Studies have shown, Omega 6 helps lower bad cholesterol LDL (low density lipoprotein), and Omega 9 helps lower LDL and maintain good cholesterol HDL (high density lipoprotein) levels. Group: Others. Camu powder acai; Brazilian Acai berry powder. Cat No: EXTC-140.
Camylofine
Camylofine is an antimuscarinic with both anticholinergic action as well as direct smooth muscle action. It can be used to treat the pain caused by smooth muscle spasm. Synonyms: Camylofine; Acamylophenine; Adopon; Avacan; Novospasmin; 3-methylbutyl 2-[2-(diethylamino)ethylamino]-2-phenylacetate. CAS No. 54-30-8. Molecular formula: C19H32N2O2. Mole weight: 320.477.
Camylofine dihydrochloride
Camylofine dihydrochloride is the salt form of Camylofine. Camylofine is an antimuscarinic with both anticholinergic action as well as direct smooth muscle action. It can be used to treat the pain caused by smooth muscle spasm. Synonyms: 3-Methylbutyl {[2-(diethylamino)ethyl]amino}(phenyl)acetate dihydrochloride. CAS No. 5892-41-1. Molecular formula: C19H34Cl2N2O2. Mole weight: 393.393.
Canada balsam
Canada balsam. Synonyms: Balsam Canada. CAS No. 8007-47-4. Pack Sizes: 25, 100 mL in glass bottle. Product ID: CDC10-0192. Molecular formula: n.a. Category: Flavoring Chemical Agents. Product Keywords: Cosmetic Ingredients; Flavoring Chemical Agents; Canada balsam; CDC10-0192; 8007-47-4; Balsam Canada; 232-362-2; MFCD00132800; 8007-47-4. Purity: 0.99. Color: yellow to very dark yellow. EC Number: 232-362-2. Physical State: Liquid. Solubility: Chloroform. Quality Level: 100. Storage: Store at 5°C to 30°C. Application: Canada balsam is used as a stable apolar hydrophobic mounting medium for light microscopy slide preparation, especially when long-term storage is desired. It is mostly applicable for cellular staining. Density: 0.99 g/mL. Product Description: Canada Balsam is a natural mounting medium obtained from balsam fir trees. It is produced from the resin of the balsam fir tree and its use can be combined with xylene-containing specimens. The optical properties of Canada Balsam are nearly identical to those of glass. Specimens must be dehydrated before using this medium. Permanent slides mounted with Canada Balsam have been stored for over a century.
Canada balsam
for microscopy. Group: Immersion oils.
Canada Balsam
Canada Balsam. Group: Biochemicals. Alternative Names: Canada Balsams; Canada Turpentine. Grades: Highly Purified. CAS No. 8007-47-4. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Canada Balsam
100g Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: N/A. CAS No. 8007-47-4. Prepack ID 31059610-100g. See USA prepack pricing.
Canada balsam solution
for microscopy. Group: Immersion oils.
Canadensolide
Canadensolide is a bislactone antibiotic isolated from Penicillium canadense, Aspergillus flavus and A. tamarii. It shows antifungal activity. Synonyms: (-)-Canadensolide; Furo(3,4-b)furan-2,4-dione, 6-butyltetrahydro-3-methylene-, (3aS,6R,6aR)-; (3aS,6R,6aR)-6-Butyl-3-methylenetetrahydrofuro[3,4-b]furan-2,4-dione. CAS No. 20421-31-2. Molecular formula: C11H14O4. Mole weight: 210.23.
Canadian balsam,neutral
Canadian balsam,neutral. Group: Polymers. Alternative Names: CANADIAN BALSAM, NEUTRAL; balsamforopticalglass; balsamoffir; Balsams,Canada; canadian; Canada turpentine; ABIES BALSAMEA (BALSAM CANADA) RESIN; AGAR, SHREDDED. CAS No. 8007-47-4. Molecular formula: 0. Mole weight: n.a.
Canadine
Canadine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DL-TETRAHYDROBERBERINE;DL-CANADINE;9,10-DIMETHOXY-5,8,13,13A-TETRAHYDRO-6H-[1,3]DIOXOLO[4,5-G]ISOQUINO[3,2-A]ISOQUINOLINE;AKOS 213-56;5,8,13,13A-TETRAHYDRO-9,10-DIMETHOXY-6H-BENZO[G]-1,3-BENZODIOXOLO[5,6-ALPHA]QUINOLIZINE;THB;TETRAHYDROBERBERINE;(+-)-can. Product Category: Heterocyclic Organic Compound. CAS No. 29074-38-2. Molecular formula: C20H21NO4. Mole weight: 339.39. Product ID: ACM29074382. Alfa Chemistry ISO 9001:2015 Certified.
Canadine
Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. Group: Biochemicals. Alternative Names: 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; 9-Deoxy-16,17-dihydroberberine; 9, 10-Dimethoxy-2, 3- (methylenedioxy) berbine; (±)-Canadine; (±)-Tetrahydroberberine; Tetrahydroberberine,; NSC 36351; NSC 94918; Tetrahydroberberine; Tetrahydroumbellatine; Xanthopuccine; dl-Canadine; dl-Tetrahydroberberine. Grades: Highly Purified. CAS No. 522-97-4. Pack Sizes: 10mg. US Biological Life Sciences.
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Canagliflozin
Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Group: Biochemicals. Alternative Names: (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol. Grades: Highly Purified. CAS No. 842133-18-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Canagliflozin
Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise. Alternative Names: Invokana;Canagliflozin anhydrous;TA-7284. CAS No. 842133-18-0. Product ID: API842133180. Molecular formula: C24H25FO5S. Mole weight: 444.5. EINECS: 695-192-1. SMILES: CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F. Appearance: White to Light Yellow Solid. Standard: Facility GMP. Category: Hypoglycemic APIs.
Canagliflozin
Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC 50 s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ 28431754. CAS No. 842133-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10451.
Canagliflozin
Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Synonyms: D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-; JNJ-24831754; TA-7284; JNJ 24831754; TA 7284; JNJ24831754; TA7284; (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol; (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl)thien-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene; Invokana; JNJ 24831754ZAE; JNJ 28431754AAA. Grade: >98%. CAS No. 842133-18-0. Molecular formula: C24H25FO5S. Mole weight: 444.52.
Canagliflozin
Canagliflozin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene. Product Category: Thiophenes. Appearance: White to Pale Yellow Solid. CAS No. 842133-18-0. Molecular formula: C24H25FO5S. Mole weight: 444.52. Purity: 95%+. Product ID: ACM842133180. Alfa Chemistry ISO 9001:2015 Certified.
Canagliflozin 2-Glucuronide
Canagliflozin 2-glucuronide is a derivative of Canagliflozin. Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion. Synonyms: Canagliflozin metabolite M5; (2S,3S,4S,5R,6R)-6-(((2S,3R,4S,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; 1-(2-O-β-D-Glucuronide-β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene. Grade: 96%. CAS No. 2648415-15-8. Molecular formula: C30H33FO11S. Mole weight: 620.64.
Canagliflozin 3-Glucuronide
Canagliflozin 3-glucuronide is a derivative of Canagliflozin. Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion. Synonyms: Canagliflozin metabolite M7; (2S,3S,4S,5R,6R)-6-(((2S,3S,4R,5R,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; 1-(3-O-β-D-Glucuronide-β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene. Grade: 96%. CAS No. 2648415-13-6. Molecular formula: C30H33FO11S. Mole weight: 620.64.
Canagliflozin 3-O-β-D-glucuronide
Canagliflozin 3-O-β-D-glucuronide is an impurity of Canagliflozin, a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Synonyms: (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-3-O-β-D-glucopyranuronosyl-D-glucitol. Molecular formula: C30H33FO11S. Mole weight: 620.64.
Canagliflozin alpha-Isomer Impurity
epi-Canagliflozin is an epimeric impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: (1R)-1,5-Anhydro-1-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-D-glucitol; epi-Canagliflozin; D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1R)-; (1R)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol; (2R,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Canagliflozin alpha-Isomer; Canagliflozin α-isomer. Grade: ≥95%. CAS No. 1589590-87-3. Molecular formula: C24H25FO5S. Mole weight: 444.53.
Canagliflozin-[d4]
Canagliflozin D4 is a labelled Canagliflozin. Canagliflozin is a medication used for the treatment of type 2 diabetes. Synonyms: (2S,3R,4R,5S,6R)-2-[3-({5-[4-fluoro(2,3,5,6-D4)phenyl]thiophen-2-yl}methyl)-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. Grade: 98% HPLC. CAS No. 1997338-61-0. Molecular formula: C24H21D4FO5S. Mole weight: 448.54.
Canagliflozin-[d6]
Canagliflozin-[d6] is the labelled analogue of Canagliflozin, which is an anti-diabetic medication used to improve blood sugar control in people with type 2 diabetes. Synonyms: Canagliflozin-D6; (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol-D6; Canagliflozin-(Methylphenyl)-d6; (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-(methyl-d3)phenyl-2,5,6-d3)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 1997338-60-9. Molecular formula: C24H19D6FO5S. Mole weight: 450.55.
Canagliflozin Defluoro Impurity
Defluoro-Canagliflozin is an impurity of Canagliflozin, a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Synonyms: Canagliflozin Impurity A; Canagliflozin Desfluoro Impurity; D-Glucitol, 1,?5-anhydro-1-C-[4-methyl-3-[(5-phenyl-2-thienyl)?methyl]?phenyl]?-, (1S)?-; (1S)-1,?5-Anhydro-1-C-[4-methyl-3-[(5-phenyl-2-thienyl)?methyl]?phenyl]?-D-glucitol; Desfluoro Canagliflozin; (2R,3S,4R,5R,6S)-2-(Hydroxymethyl)-6-(4-methyl-3-((5-phenylthiophen-2-yl)methyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol. Grade: ≥95%. CAS No. 842133-16-8. Molecular formula: C24H26O5S. Mole weight: 426.54.
Canagliflozin Furanose Form (Mixture of Anomers)
Canagliflozin Furanose Form (Mixture of Anomers) is an impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: D-Galactitol, 1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-; Canagliflozin-10; Canagliflozin Impurity 17; (2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)tetrahydrofuran-3,4-diol. CAS No. 2161394-94-9. Molecular formula: C24H25FO5S. Mole weight: 444.52.
Canagliflozin hemihydrate
Canagliflozin hemihydrate is a highly potent and selective inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. It is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes. Uses: The potential treatment of type 2 diabetes. Synonyms: (3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hemihydrate; JNJ 28431754 hemihydrate; TA 7284 hemihydrate; JNJ-24831754-ZAE hemihydrate; JNJ-28431754-AAA hemihydrate; (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol hydrate (2:1); Cagliflozin hydrate; Invokana hemihydrate; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate. Grade: >98%. CAS No. 928672-86-0. Molecular formula: C24H25FO5S.1/2H2O. Mole weight: 453.53.
Canagliflozin hemihydrate
Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC 50 s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ 28431754 hemihydrate. CAS No. 928672-86-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-I0383.
Canagliflozin Impurity 14
Canagliflozin Impurity 14 is an impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(3-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-; (2S,3R,4R,5S,6R)-2-(3-((5-(3-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 842133-17-9. Molecular formula: C24H25FO5S. Mole weight: 444.52.
Canagliflozin Impurity 17
Canagliflozin Impurity 17 is an impurity of Canagliflozin, which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor used in the treatment of type 2 diabetes and obesity. Synonyms: Methanone, [5-(4-fluorophenyl)-2-thienyl](5-β-D-glucopyranosyl-2-methylphenyl)-; Methanone, (5-(4-fluorophenyl)-2-thienyl)(5-beta-D-glucopyranosyl-2-methylphenyl)-; Canagliflozin impurity 12; (5-(4-Fluorophenyl)thiophen-2-yl)(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)methanone; [5-(4-Fluorophenyl)-2-thienyl](5-β-D-glucopyranosyl-2-methylphenyl)methanone; Canagliflozin Impurity 2; Canagliflozin Keto Impurity. Grade: ≥95%. CAS No. 1951467-28-9. Molecular formula: C24H23FO6S. Mole weight: 458.50.
Canagliflozin Impurity 20
Canagliflozin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol. CAS No. 1672658-93-3. Molecular formula: C24H25FO6S. Mole weight: 460.52. Catalog: APB1672658933.
Canagliflozin impurity 25
Canagliflozin impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1071929-08-2. Molecular formula: C18H12FIOS. Mole weight: 422.26. Catalog: APB1071929082.
Canagliflozin Impurity 52
Canagliflozin Impurity 52. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene. CAS No. 1030825-20-7. Molecular formula: C18H14BrFS. Mole weight: 361.27. Catalog: APB1030825207.
Canagliflozin Impurity B
Canagliflozin Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1132832-75-7. Molecular formula: C18H12BrFOS. Mole weight: 375.25. Catalog: APB1132832757.
Canagliflozin Monoacetyl Impurity
Canagliflozin Monoacetyl Impurity is an impurity of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: ((2R,3S,4R,5R,6S)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate; Canagliflozin impurity 03. CAS No. 2146135-87-5. Molecular formula: C26H27FO6S. Mole weight: 486.55.
Canagliflozin Related Impurity 10
an impurity of Canagliflozin. Synonyms: β-D-Glucopyranose, 1-C-[3-[[5-(4-fluorophenyl)?-2-thienyl]?methyl]?-4-methylphenyl]?-. Grade: > 95%. CAS No. 1799552-91-2. Molecular formula: C24H25FO6S. Mole weight: 460.53.
Canagliflozin Related Impurity 14
2-(4-Fluorophenyl)-thiophene can be used to prepare Canagliflozin as sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for treatment of type 2 diabetes mellitus. Synonyms: Thiophene, 2-(4-fluorophenyl)?-. Grade: > 95%. CAS No. 58861-48-6. Molecular formula: C10H7FS. Mole weight: 178.23.
Canagliflozin Related Impurity 9
an impurity of Canagliflozin. Synonyms: (3R,4S,5R,6R)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one. Grade: > 95%. CAS No. 32384-65-9. Molecular formula: C18H42O6Si4. Mole weight: 466.86.
Canagliflozin Ring Opening Impurity
Canagliflozin Ring Opening Impurity is an impurity of Canagliflozin, which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor used in the treatment of type 2 diabetes and obesity. Synonyms: (2S,3R,4R,5R)-1-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol; D-Glucitol, 1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-; 1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol. Molecular formula: C24H27FO6S. Mole weight: 462.53.
Canagliflozin Tetraacetate
Canagliflozin Tetraacetate is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and is used in the treatment of type 2 diabetes and obesity. Synonyms: (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-Tetraacetate; Canagliflozin impurity 05; Tetra Acetyl Canagliflozin. Grade: 98%. CAS No. 866607-35-4. Molecular formula: C32H33FO9S. Mole weight: 612.66.
Canakinumab
Canakinumab is a recombinant human anti-IL-1β monoclonal antibody used for the treatment of immune disorders such as rheumatoid arthritis and cryopyrin-associated periodic syndrome (CAPS). Synonyms: Ilaris; ACZ 885; ACZ885. CAS No. 914613-48-2.
Canakinumab
Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC 50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Ilaris; ACZ 885. CAS No. 914613-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108810.
Cananga Oil
Cananga oil is an essential oilsderived from the flowers of cananga tree, which is native to Asia. It has a sweet, floral and slightly woody aroma The height of the Cananga tree can make harvesting dangerous, as it can reach several dozen meters The Cananga blossoms are then hydro-distilled to obtain the essential oil. In perfumery, Cananga essential oilshas long been viewed as a less-expensive alternative to the very pricey ylang-ylang essence. Today, Cananga essential oilshas been deemed as having it's own olfactory qualities. It has strong floral character and jasmine and woody facets. In aromatherapy, this oil is used as an antidepressant and as a sedative. it is also considered to be an aphrosidiac and is believed to stimulate the circulatory system. Uses: Cosmetic and Care, Essential Oils, Flavoring. Group: Plant Extracts. INCI Names: Cananga Odorata Flower Oil. Grades: FOOD GRADE. CAS No. 93686-30-7; 68606-83-7. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CN-001. Olfactive Profile: Floral, sweet, slightly woody, ylang-ylang like, balsamic. EC No: 281-092-1. FEMA No: 2232. Origin: Indonesia.
New Jersey
Canbisol
Canbisol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Canbisol;Nabidrox (Canbisol, Dihydronabilone);3-(1,1-Dimethylheptyl)-6a,7,8,9,10,10a-hexahydro-6,6-dimethyl-6H-dibenzo[b,d]pyran-1,9-diol. Product Category: Heterocyclic Organic Compound. CAS No. 56689-43-1. Molecular formula: C24H38O3. Mole weight: 374.561. Product ID: ACM56689431. Alfa Chemistry ISO 9001:2015 Certified.
Cancer Cell Differentiation Compound Library
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2140. Categories: Cancer Cell Differentiation Compounds Libraries.
A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50=12nM; PC3 lysate) and murine (IC50=20nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80mg/kg/day; o.g.). Also inhibits blood carboxylesterase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
cancer procoagulant
Apparently produced only by malignant and fetal cells. Group: Enzymes. Enzyme Commission Number: EC 3.4.22.26. CAS No. 109456-80-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4200; cancer procoagulant; EC 3.4.22.26; 109456-80-6. Cat No: EXWM-4200.
Cancer related antigens BST-2 (126-134)
Cancer related antigens BST-2 (126-134) is a peptide corresponding to residues 126-134 of BST-2. BST-2 is a unique innate immunity gene with both antiviral and pro-tumor functions and therefore can serve as a paradigm for understanding the roles of other innate immunity genes in cancers. Synonyms: Cancer related antigens Bone marrow stromal antigen 2 (126-134).
Cancer/testis antigen 1 (119-138)
Cancer/testis antigen 1 (119-138) is a 20-aa peptide. Cancer/testis antigen 1 is an archetypical example of a CTA with restricted expression to germ cells and placental cells and re-expression in tumor cells. Synonyms: NY-ESO-1 (119-138); Cancer/testis antigen 6.1 (119-138); L antigen family member 2 (119-138).
Cancer/testis antigen 1 (119-143)
Cancer/testis antigen 1 (119-143) is a 25-aa peptide. Cancer/testis antigen 1 is an archetypical example of a CTA with restricted expression to germ cells and placental cells and re-expression in tumor cells. Synonyms: NY-ESO-1 (119-143); Cancer/testis antigen 6.1 (119-143); L antigen family member 2 (119-143).
Cancer/testis antigen 1 (121-130)
Cancer/testis antigen 1 (121-130) is a 10-aa peptide. Cancer/testis antigen 1 is an archetypical example of a CTA with restricted expression to germ cells and placental cells and re-expression in tumor cells. Synonyms: NY-ESO-1 (121-130); Cancer/testis antigen 6.1 (121-130); L antigen family member 2 (121-130).
Cancer/testis antigen 1 (123-137)
Cancer/testis antigen 1 (123-137) is a 15-aa peptide. Cancer/testis antigen 1 is an archetypical example of a CTA with restricted expression to germ cells and placental cells and re-expression in tumor cells. Synonyms: NY-ESO-1 (123-137); Cancer/testis antigen 6.1 (123-137); L antigen family member 2 (123-137).
Cancer/testis antigen 1 (124-134)
Cancer/testis antigen 1 (124-134) is a 11-aa peptide. Cancer/testis antigen 1 is an archetypical example of a CTA with restricted expression to germ cells and placental cells and re-expression in tumor cells. Synonyms: NY-ESO-1 (124-134); Cancer/testis antigen 6.1 (124-134); L antigen family member 2 (124-134).