A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 with Ki of 19 nM. It has been shown to inhibit calpain-2 with Ki of 120 nM and human cathepsin B with Ki of 750 nM. Calpain inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Synonyms: Z-L-Nva-CONH-CH2-2-Py. Grade: ≥90%. CAS No. 181769-57-3. Molecular formula: C26H34N4O5. Mole weight: 482.6.
Calpastatin Peptide
A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC?? = 20 nM for purified rabbit calpain II). Group: Fluorescence/luminescence spectroscopy.
Calpastatin Peptide, Negative Control
A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide. Group: Fluorescence/luminescence spectroscopy.
Calpeptin
Calpeptin. Group: Biochemicals. Grades: Purified. CAS No. 117591-20-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Synonyms: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. Grade: >98%. CAS No. 117591-20-5. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Calpeptin
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID 50 of 40 nM for Calpain I in human platelets [1]. Calpeptin is also an inhibitor of cathepsin K [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 117591-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100223.
A cell-permeable calpain inhibitor (ID?? = 52 nM for calpain-1; ID?? = 34 nM for calpain-2; ID?? = 138 nM for papain). Group: Fluorescence/luminescence spectroscopy.
Calphostin A
Calphostin A is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 120461-92-9. Molecular formula: C44H38O12. Mole weight: 758.76.
Calphostin B
Calphostin B is a protein kinase C inhibitor produced by cladosporium cladosporioides. CAS No. 124824-06-2. Molecular formula: C37H34O11. Mole weight: 654.65.
Calphostin C
Calphostin C is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: UCN 1028 C, PKF 115-384. Grade: >95% by HPLC. CAS No. 121263-19-2. Molecular formula: C44H38O14. Mole weight: 790.76.
Calphostin C
0mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C44H38O14. CAS No. 121263-19-2. Prepack ID 33060444-0mg. Molecular Weight 790.76. See USA prepack pricing.
Calphostin C
Calphostin C is a highly selective PKC inhibitor ( IC 50 =0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCN-1028C. CAS No. 121263-19-2. Pack Sizes: 100 μg. Product ID: HY-105416.
Calphostin C (Antibiotic UCN-1028 C, UCN 1028 C)
Calphostin C is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. It is a potent and specific inhibitor of protein kinase C with inhibition being light dependent. Also shown to inhibit cell proliferation and induce apoptosis in vitro. Group: Biochemicals. Alternative Names: Antibiotic UCN-1028 C, UCN 1028 C. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2
A cell permeable, highly specific inhibitor of protein kinase C (IC?? = 50 nM) that interacts with the protein's regulatory domain by competing at the binding site of diacylglycerol and phorbol esters. Group: Fluorescence/luminescence spectroscopy.
Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-dependent. PKA, PKG, DAG kinase, phospholipase D1 and D2, myosin light chain kinase and c-Src inhibitor. Anticancer compound. Inhibits cell proliferation and strongly induces apoptosis in vitro. Inducer of endoplasmic reticulum ER-stress. Shown to directly and potently block L-type Ca channels. Calphostin C specifically inhibits contraction-stimulated glucose transport but not insulin-stimulated glucose transport in skeletal muscle. Wnt/beta-catenin/lef-1 signaling inhibitor. beta-catenin/TCF antagonist. Inhibits Wnt-activated genes in a dose-dependent fashion. Source:Cladosporium cladosporioides sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 121263-19-2. Pack Sizes: 100ug, 1mg. Molecular Formula: C44H38O14 , Molecular Weight: ~790.8. US Biological Life Sciences.
Worldwide
Calphostin D
Calphostin D is a protein kinase C inhibitor produced by cladosporium cladosporioides. Synonyms: Phleichrome. CAS No. 124986-26-1. Molecular formula: C30H30O10. Mole weight: 550.55.
Calpinactam
Specific anti-mycobacterial. Inhibits growth of Mycobacteria smegmatis but also Mycobacteria tuberculosis. M. smegmatis is used as a model for mycobacterial species. It is useful for the research analysis of other Mycobacteria species in laboratory experiments. M. smegmatis is commonly used in work on the mycobacterium species, since it is a "fast grower" and non-pathogenic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1205538-83-5. Pack Sizes: 250ug, 1mg. Molecular Formula: C38H57N9O8. US Biological Life Sciences.
recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Calretinin from mouse
recombinant, expressed in E. coli, ?90% (SDS-PAGE), ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Calteridol
Desgadolinium Gadoteridol is an impurity of Gadoteridol. Gadoteridol is a gadolinium-based MRI contrast agent. It is sold under the brand name ProHance. Synonyms: calteridol; CHEBI:37387; 1,4,7,10-Tetraazacyclododecane-1,4,7-triaceticacid,10-(2-hydroxypropyl)-; 2,2',2'-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic acid; ACMC-20mop4. Grade: 95%. CAS No. 120041-08-9. Molecular formula: C17H32N4O7. Mole weight: 404.46.
Calu-6 Transfection Reagent
Transfection Reagent for Calu6 Lewis Lung Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1728.
Nevada, Texas, USA
Calvatic acid
Calvatic acid is an antibiotic produced by Calvatia craniformis (Shw.) Fr. It has anti-gram-positive and negative bacteria (weak) activity, and inhibits Yoshida sarcoma and L-1210 cell activity. Synonyms: p-Carboxyphenylazoxycyanide; Benzoic acid, 4-(cyano-NNO-azoxy)-. CAS No. 54723-08-9. Molecular formula: C8H5N3O3. Mole weight: 191.14.
Calvinphos
Calvinphos. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nestyne; Calvinphos; Caviphos. Product Category: Heterocyclic Organic Compound. CAS No. 6465-92-5. Molecular formula: C10H15CaCl6O12P3. Mole weight: 672.936183 [g/mol]. Purity: 0.96. IUPACName: calcium; 2,2-dichloroethenyl dimethyl phosphate; 2,2-dichloroethenyl methyl phosphate. Product ID: ACM6465925. Alfa Chemistry ISO 9001:2015 Certified.
Calvulanic acid
Calvulanic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 58001-44-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H9NO5. US Biological Life Sciences.
Worldwide
Calycanthine
Calycanthine. Group: Biochemicals. CAS No. 595-05-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CALYCANTHINE
Calycanthine is an alkaloid isolated from seeds of Chimonanthus praecox. Calycanthine exhibits potent antifungal activity against five plant pathogenic fungi including Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sclerotinia sderotiorum and Fusarium oxysportium. Synonyms: (1S,2R,10S,11R)-21,24-dimethyl-3,12,21,24-tetraazahexacyclo[9.7.3.3(2,10).0(1,10).0(4,9).0(13,18)]tetracosa-4,6,8,13,15,17-hexaene; (4bS,5R,10bS,11R)-13,18-dimethyl-5,6,11,12-tetrahydro-5,10b:11,4b-di(epiminoethano)dibenzo[c,h]-2,6-naphthyridine. Grade: >98%. CAS No. 595-05-1. Molecular formula: C22H26N4. Mole weight: 346.478.
Calycanthoside
Calycanthoside is a coumarin found in Eleutherococcus senticosus that exhibits anti-inflammatory and antibacterial effects. Synonyms: Isofraxidin 7-O-β-D-glucopyranoside; 6,8-Dimethoxy-7-(beta-D-glucopyranosyloxy)coumarin; 7-(beta-D-Glucopyranosyloxy)-6,8-dimethoxy-2H-1-benzopyran-2-one. Grade: 98.5%. CAS No. 483-91-0. Molecular formula: C17H20O10. Mole weight: 384.34.
Calyciphylline A isolated from the branch of Daphniphyllum macropodum Miq. Synonyms: Methyl (1R,2S,3R,5R,6S,8R,10S,16R,17R)-2,6-dimethyl-20-oxo-8-azahexacyclo[11.5.1.11,5.02,10.03,8.016,19]icos-13(19)-ene-17-carboxylate 8-oxide. Grade: 98.5%. CAS No. 596799-30-3. Molecular formula: C23H31NO4. Mole weight: 385.5.
Calycosin
Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclosin. CAS No. 20575-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0519.
Calycosin
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Calycosin
Calycosin. Group: Biochemicals. Grades: Highly Purified. CAS No. 20575-57-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H12O5. US Biological Life Sciences.
Worldwide
CALYCOSIN
Pellitorine isolated from the herb of Astragalus membranaceus Bge. var. mongholicus. It may be an effective skin-lightening agent. Uses: Antineoplastic effects. Synonyms: 7,3'-DIHYDROXY-4'-METHOXYISOFLAVONE; 3'-HYDROXYFORMONONETIN; 3',7-DIHYDROXY-4'-METHOXYISOFLAVONE; 3-(3-Hydroxy-4-methoxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one; 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one. Grade: 0.99. CAS No. 20575-57-9. Molecular formula: C16H12O5. Mole weight: 284.26.
Calycosin 7-O- β-D-glucopyranoside
Calycosin 7-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 20633-67-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Calycosin 7-O-β-D-glucopyranoside
Calycosin-7-O-β-D-glucoside, a melanin biosynthesis inhibitor, is isolated from the methanol extract of astragalus. It showed scavenging activity to DPPH radicals. It is anticipated to be a promising anti-HIV agent. Synonyms: calycosin-7-O-beta-D-glucopyranoside; Calycosin 7-o-beta-D-glucoside; Calycosin-7-O-beta-D-glucoside; Calycosin 7-O-gluc. Grade: >98%. CAS No. 20633-67-4. Molecular formula: C22H22O10. Mole weight: 446.40.
Calycosin-7-O- β-D-glucoside
Calycosin-7-O- β-D-glucoside. Group: Biochemicals. Alternative Names: Calycosin-7-O- β-D-glucoside; Calycosin 7-glucoside. Grades: Plant Grade. CAS No. 20633-67-4. Pack Sizes: 20mg. Molecular Formula: C22H22O10, Molecular Weight: 446.404. US Biological Life Sciences.
Worldwide
Calycosin 7-O-?-D-glucopyranoside
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Calyculin A
Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Calyculin A. CAS No. 101932-71-2. Pack Sizes: 10 ?g. Product ID: HY-18983.
CALYCULIN A
Calyculin A is a effective inhibitor of the catalytic subunit of type-2A phosphatase as well as the type-1 phosphatase. IC50: 0.5 to 1 nM and 2 nM,respectively. It has lower IC50 value than okadaic acid which is a active blocker of phosphatase mentioned a. Uses: Calyculin a is a effective inhibitor of the catalytic subunit of type-2a phosphatase as well as the type-1 phosphatase. Synonyms: CALYCULIN A; CALYCULIN A, DISCODERMIA CALYX; calyculin A from discodermia calyx; CALYCULIN A FROM DISCODERMIA CALYX, 10 U G; N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentam; L-Ribonamide. Grade: >98 %. CAS No. 101932-71-2. Molecular formula: C50H81N4O15P. Mole weight: 1009.17.
Calystegine B2 is a bioactive compound known for its potential therapeutic properties in studying neurodegenerative diseases, such as Alzheimer's and Parkinson's. Extensive research has revealed its ability to inhibit enzymes involved in the progression of these diseases, making it a promising candidate for drug development. Synonyms: Nortropanoline; 8-Aza-bicyclo[3.2.1]octane-1,2,3,4-tetraol. CAS No. 127414-85-1. Molecular formula: C7H13NO4. Mole weight: 175.19.
Calystegine b3
Calystegine b3. Uses: Designed for use in research and industrial production. CAS No. 178231-95-3. Molecular formula: C7H13NO4. Mole weight: 175.19. Purity: 0.96. Product ID: ACM178231953. Alfa Chemistry ISO 9001:2015 Certified.
Calyxamine B
Calyxamine B is a natural alkaloid found in the herbs of Salsola tetrandra. Synonyms: 1-(2,2,6,6-Tetramethyl-4-piperidinylidene)acetone. Grade: >98%. CAS No. 150710-72-8. Molecular formula: C12H21NO. Mole weight: 195.3.
CAM2602
CAM2602 is an Aurora A-TPX2 interaction inhibitor that has a binding affinity of 19 nM to Aurora A. CAM2602 can inhibit the growth of pancreatic cancer cells. In solid tumor transplant models, CAM2602 can increase the proportion of PH3 positive cells while reducing the proportion of P-Thr288 Aurora A positive cells, thereby inhibiting tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3056388-47-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168022.
CAM833
CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758364-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150147.
Camalexin
Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 135531-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119502.
analytical standard. Group: Antifungals standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolites.
Cambendazole
Cambendazole is one of the most effective agents for the research of human strongyloidiasis and [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26097-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107483.
Cambendazole-[d7] is the labelled analogue of Cambendazole, which acts as an anthelmintic used in the treatment of Chagas' disease. Synonyms: Cambendazole-D7; (2-Thiazol-4-yl-1H-benzimidazol-5-yl)-carbamic acid isopropyl-D7 ester; 2-(4-Thiazolyl)-5-benzimidazolecarbamic Acid-d7 Isopropyl Ester; [2-(4-Thiazolyl)-1H-benzimidazol-5-yl]carbamic Acid-d7 1-Methylethyl Ester; 2-(4-Thiazolyl)-5-isopropoxycarbonylaminobenzimidazole-d7; Bonlam-d7; Cambenzole-d7; Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate-d7; NSC 377071-d7; Novazole-d7; Noviben-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1228182-48-6. Molecular formula: C14H7D7N4O2S. Mole weight: 309.39.
Cambinol
?97% (HPLC), white powder. Group: Fluorescence/luminescence spectroscopy.
Cambinol
Cambinol is a cell-permeable inhibitor of SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Synonyms: 2,3-dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-pyrimidinone; Cambinol; NSC 112546; SIRT1 Inhibitor II; SIRT2 Inhibitor VI; SIRT 1/2 inhibitor IV; NSC112546; NSC-112546; NSC 112546. CAS No. 14513-15-6. Molecular formula: C21H16N2O2S. Mole weight: 360.43.
Cambinol
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Uses: Designed for use in research and industrial production. Additional or Alternative Names: cambinol, NSC112546, NSC-112546, SIRT1/2 Inhibitor IV, Cambinol, 14513-15-6, 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, AC1MMYEF, NCIStruc1_001428, NCIStruc2_001159, SureCN3332758, CHEMBL491960, CTK8G3107, HMS3261K21, CCG-37240, DNC009417, NCGC00014121, NCI112546, AKOS002364304, AG-D-88787, CCG-221684. Product Category: Inhibitors. CAS No. 14513-15-6. Molecular formula: C21H16N2O2S. Mole weight: 360.43. Purity: 0.96. IUPACName: 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one. Density: 1.41g/cm³. Product ID: ACM14513156. Alfa Chemistry ISO 9001:2015 Certified. Categories: Campanology.
Cambinol
Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 ?M and 59 ?M, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14513-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100732.
Camel Hair Brushes (3/pkg)
Camel Hair Brushes (3/pkg). Group: Windows & spheres.
Camelliaside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 135095-52-2. Pack Sizes: 10mg. Molecular Formula: C33H40O20, Molecular Weight: 756.66. US Biological Life Sciences.
Worldwide
Camelliaside B
Camelliaside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 131573-90-5. Pack Sizes: 10mg. Molecular Formula: C32H38O19, Molecular Weight: 726.63. US Biological Life Sciences.
Worldwide
camelliol C synthase
The product is 97% camelliol, 2% achilleol A and 0.2% β-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC 5.4.99.39, β-amyrin synthase. Group: Enzymes. Synonyms: CAMS1; LUP3 (gene name). Enzyme Commission Number: EC 5.4.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5579; camelliol C synthase; EC 5.4.99.38; CAMS1; LUP3 (gene name). Cat No: EXWM-5579.
FHD-286 is a selective, oral inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor. FHD-286 has the potential for the research of BAF (BRG1/BRM-associated factor)-related disorders such as acute myeloid leukemia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FHD-286. CAS No. 2671128-05-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144835.