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| Product | Description | |
|---|---|---|
| Dorzolamide EP Impurity B (Hydrochloride) | Dorzolamide EP Impurity B (Hydrochloride). Uses: For analytical and research use. Alternative Names: (4R,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride. CAS No. 120279-37-0. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.90. Catalog: APB120279370. |  |
| Dorzolamide EP Impurity C | Dorzolamide EP Impurity C. Uses: For analytical and research use. Alternative Names: (2-(((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)ethyl)boronic acid. Molecular formula: C10H17BN2O6S3. Mole weight: 368.26. Catalog: APB05105. | |
| Dorzolamide EP Impurity C (Hydrochloride) | Dorzolamide EP Impurity C (Hydrochloride). Uses: For analytical and research use. Alternative Names: (2-(((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)ethyl)boronic acid hydrochloride. Molecular formula: C10H17BN2O6S3·HCl. Mole weight: 368.26 36.46. Catalog: APB05104. | |
| Dorzolamide EP Impurity D (Hydrochloride) | Dorzolamide EP Impurity D (Hydrochloride). Uses: For analytical and research use. Alternative Names: (4S,6S)-4-amino-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride. CAS No. 164455-27-0. Molecular formula: C8H12N2O4S3·HCl. Mole weight: 332.847. Catalog: APB164455270. | |
| Dorzolamide HCl | Dorzolamide HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H16N2O4S3·ClH. US Biological Life Sciences. |  Worldwide |
| Dorzolamide HCL USP | Dorzolamide HCL USP. |  CA, FL & NJ |
| Dorzolamide hydrochloride | Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L671152 hydrochloride; MK507 hydrochloride. CAS No. 130693-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 100 mg; 250 mg. Product ID: HY-B0109A. |  |
| Dorzolamide Hydrochloride | Dorzolamide hydrochloride is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Alternative Names: Dorzolamide HCl; TRUSOPT; (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride; (4S-trans)-4-(ethylamino)-5,6-dihydro-6-methyl4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride. Grades: >98%. CAS No. 130693-82-2. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.886. |  |
| Dorzolamide hydrochloride,pharma130693-82-2;122028-36-8;122028-16-4 | Dorzolamide hydrochloride,pharma130693-82-2;122028-36-8;122028-16-4. CAS No. 120279-36-9. Purity: 96%. Product ID: ACM120279369. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Dorzolamide Impurity 4 | Dorzolamide Impurity 4. Uses: For analytical and research use. CAS No. 120279-26-7. Molecular formula: C8H11NO5S3. Mole weight: 297.36. Catalog: APB120279267. | |
| Dorzolamide Impurity 6 | Dorzolamide Impurity 6. Uses: For analytical and research use. Molecular formula: C10H17BN2O6S3. Mole weight: 368.24. Catalog: APB07668. | |
| Dorzolamide Impurity 7 (Mixture of Diastereomers) | Dorzolamide Impurity 7 (Mixture of Diastereomers). Uses: For analytical and research use. Alternative Names: 2-(ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic acid. Molecular formula: C14H20N2O8S3. Mole weight: 440.04. Catalog: APB05103. | |
| Dorzolamide Maleic Acid Adduct | An impurity of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor primarily used to lower intraocular pressure in conditions such as glaucoma and ocular hypertension. Alternative Names: N-Ethyl-N-((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)aspartic acid; 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid; Dorzolamide Maleic Acid. Grades: ≥95%. Molecular formula: C14H20N2O8S3. Mole weight: 440.51. | |
| Dorzolamide Maleic Acid Adduct | Dorzolamide Maleic Acid Adduct. Group: Biochemicals. Alternative Names: 2-(Ethyl((4S,6S)-6-methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)amino)succinic Acid. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C14H20N2O8S3, Molecular Weight: 440.51. US Biological Life Sciences. | Worldwide |
| Dosimertinib-d5 mesylate | Dosimertinib-d5 (mesylate) is a potent and orally active EGFR inhibitor. Dosimertinib-d5 (mesylate) decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib-d5 (mesylate) shows antiproliferative and anti-tumor activity. Dosimertinib-d5 (mesylate) has the potential for the research of non-small-cell lung cancer (NSCLC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9291-d5 mesylate; Mereletinib-d5 mesylate. CAS No. 2403760-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142283AS. | |
| Dostarlimab | Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TSR-042; ANB-011; WBP-285. CAS No. 2022215-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99345. | |
| Dot | Dot - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Dot1L-IN-5 | Dot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 of 0.17 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2565705-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135128. | |
| DOTA | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals. Group: Biochemicals. Alternative Names: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan. Grades: Highly Purified. CAS No. 60239-18-1. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| DOTA(allyl ester)3 | DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Alternative Names: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61. | |
| DOTA-benzene | DOTA-benzene. CAS No. 123317-52-2. Purity: ≥98%. Product ID: ACM123317522. Molecular formula: C23H35N5O8. Mole weight: 509.55. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTA-ECL1i | DOTA-ECL1i is a conjugate of the CCR2 inhibitor ECL1i (HY-P11553) and DOTA. When radiolabeled with 68Ga, DOTA-ECL1i serves as a PET tracer that targets CCR2 expression. DOTA-ECL1i can be used in research related to pulmonary fibrosis, cardiac injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer, and pancreatic cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2850189-48-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11553B. | |
| DOTAGA-anhydride | DOTAGA-anhydride is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide drug conjugates (RDCs). DOTAGA-anhydride has been successfully used for labeling antibodies (e.g., Trastuzumab (HY-P9907)). DOTAGA-anhydride can be used for the synthesis of a bimodal tag for Single-photon emission computed tomography (SPECT) or PET/optical imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375475-53-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W087187. | |
| DOTAGA-FAP-2286-ALB | DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability (e.g., with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114056-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173374. | |
| DOTA-GA-maleimide | DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn, enabling 111In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800229-46-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157977. | |
| DOTA-GA(tBu)4 | DOTA-GA(tBu)4. Alternative Names: 5-(tert-Butoxy)-5-oxo-4-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)pentanoic acid. CAS No. 306776-79-4. Molecular formula: C35H64N4O10. Mole weight: 700.9. | |
| DOTA-GPC3 targeting peptide 2 | DOTA-GPC3 targeting peptide 2 (Sequence 30) is a RDC peptide targeting GPC3, with Kd of 0.3 nM. DOTA-GPC3 targeting peptide 2 is composed of DOTA and GPC3 targeting peptide 2. DOTA-GPC3 targeting peptide 2 can be labeled with radioactive elements[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3066439-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W1124925. | |
| DOTA-JR11 | DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research[1]. DOTA-JR11 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Satoreotide tetraxetan. CAS No. 1039726-31-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5128. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126. | |
| DOTA-LM3 | DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. DOTA-LM3 can be labeled with 177Lu and 68Ga for imaging and detecting tumors. Alternative Names: DOTA-Cpa-(D-Cys)-Tyr-[D-Aph(Cbm)]-Lys-Thr-Cys-(D-Tyr)-NH2 [Disulfide Bond (D-Cys)2/Cys7]; DOTA-Cpa-D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys-D-Tyr-NH2 [Disulfide Bond (D-Cys)2/Cys7]. CAS No. 1192362-32-5. Molecular formula: C69H93ClN16O19S2. Mole weight: 1550.16. | |
| DOTAM-mono-acid | DOTAM-mono-acid is a chelator with DOTAM as its core. DOTAM-mono-acid contains a carboxylic acid group that can be activated to form an amide bond with the N-terminus of a peptide. DOTAM-mono-acid can form peptide conjugates for radiometal labeling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 913528-04-8. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg. Product ID: HY-W717743. | |
| DOTAMTATE | DOTAMTATE is a somatostatin analogue. DOTAMTATE marked 212Pb is promising for research of somatostatin receptor positive neuroendocrine tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2415661-92-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10920. | |
| DOTA-?NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 170908-81-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-128890. | |
| DOTA-NHS-ester | DOTA-NHS-ester. Alternative Names: 2,2',2''-(10-(2-((2,5-Dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid. CAS No. 170908-81-3. Purity: 98%. Product ID: ACM170908813-1. Molecular formula: C20H31N5O10. Mole weight: 501.49. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTA-NHS-ester | DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. Alternative Names: Tetraxetan N-hydroxysuccinimide; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester. Grades: ≥95%. CAS No. 170908-81-3. Molecular formula: C20H31N5O10. Mole weight: 501.49. | |
| DOTA-NHS-ester hexafluorophosphate TFA | DOTA-NHS-ester hexafluorophosphate TFA. CAS No. 1823122-52-6. Purity: ≥95%. Product ID: ACM1823122526. Molecular formula: C20H31N5O10·C2HF3O2·HPF6. Mole weight: 761.48. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTA-NHS-ester Hexafluorophosphate TFA Salt (Technical Grade) | DOTA-NHS-ester Hexafluorophosphate TFA Salt is used as a reagent in the preparation of metal or radiometal-labeled-urea- and carbamate-based PSMA inhibitors for PSMA-targeted imaging and radiotherapy. Alternative Names: 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid mono(N-hydroxysuccinimidyl) ester Hexafluorophosphate TFA Salt; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid mono(N-hydroxysuccinimide ester) Hexafluorophosphate TFA Salt. CAS No. 1823122-52-6. Molecular formula: C20H31N5O10·C2HF3O2·HPF6. Mole weight: 501.49 + 114.02 + 145.97. | |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Alternative Names: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grades: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70. | |
| DOTA-NOC | DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1]. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: DOTA-Nal3-octreotide. CAS No. 619300-53-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2112. | |
| DOTAP | DOTAP is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. DOTAP is a good immunomodulator, the antigen presenting capacity of antigen presenting cells can be obviously improved by preparing cationic liposome by packaging polypeptide or protein antigens and the DOTAP, and the DOTAP can activate the antigen presenting cells through a mitogen-activated protein kinase (MAP) pathway to induce specific immune response, unlike the traditional adjuvant which activates the antigen presenting cells through a Toll-like receptor pathway. Alternative Names: 1,2-Dioleoyloxy-3-(trimethylammonium)propane; 1,2-Dotap; N,N,N-Trimethyl-2,3-bis((-1-oxo-octadecenyl)oxy)-(Z,Z)-1-propanaminium; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium. CAS No. 113669-21-9. Molecular formula: C42H80NO4. Mole weight: 663.09. | |
| DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride. CAS No. 132172-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-112754A. | |
| DOTAP chloride (GMP Like) | DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like). CAS No. 132172-61-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112754AGL. | |
| DOTAP/DC-CHOL (50:50) Cationic Liposomes | Liposomes are monolayers. Due to their small size, they do not settle on the bottom of the vial. If other sizes are required, please specify. when ordering. | |
| DOTAP:DOPC (20:80) Cationic Liposomes | Liposomes are monolayers. Due to their small size, they do not settle on the bottom of the vial. If other sizes are required, please specify. when ordering. | |
| DOTAP:DOPC (30:70) Cationic Liposomes | Liposomes are monolayers. Due to their small size, they do not settle on the bottom of the vial. If other sizes are required, please specify. when ordering. | |
| DOTAP / DOPE (50:50) Cationic Liposomes | Liposomes are monolayers. Due to their small size, they do not settle on the bottom of the vial. If other sizes are required, please specify. when ordering. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104986-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140752. | |
| DOTA-PEG5-azide | DOTA-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. DOTA-PEG5-azide can be used in the synthesis of a series of PROTACs. Alternative Names: DOTA-PEG5-C2-azide. Grades: 95%. Molecular formula: C28H52N8O12. Mole weight: 692.76. | |
| DOTA-PEG5-C6-DBCO | DOTA-PEG5-C6-DBCO is a PEG linker containing DOTA and DBCO moieties. DBCO is used in Click Chemistry reactions due to its high strain energy. The DOTA group can be ionized and is susceptible for chelating di- and trivalent cations. DOTA can also be used for imaging diagnostic techniques. Grades: 98%. Molecular formula: C49H71N7O14. Mole weight: 982.2. | |
| DOTAP mesylate | DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. CAS No. 252769-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W127426. | |
| DOTAP methylsulfate | DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design | |
| Dotarizine | Dotarizine. Group: Biochemicals. Alternative Names: 1-(Diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine; FI-6026. Grades: Highly Purified. CAS No. 84625-59-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C29H34N2O2. US Biological Life Sciences. | Worldwide |
| DOTATATE | DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4]. DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oxodotreotide. CAS No. 177943-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-106244. | |
| DOTATATE acetate | DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4]. DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Oxodotreotide acetate. CAS No. 177943-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106244A. | |
| DOTATATE acetate | DOTATATE acetate is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE acetate is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Alternative Names: L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate (salt) (1:x); DOTA-(Tyr3,Thr8)-Octreotide acetate; DOTA-[Tyr3] Octreotide Acid (Octreotate) acetate; DOTA-octreotate acetate; DOTA-[Tyr3]-Octreotide Acid acetate. Grades: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2.xC2H4O2. Mole weight: 1435.63 (free base). | |
| DOTA-Thiol | DOTA-Thiolis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-Thiol can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Category: Signaling pathways. CAS No. 865470-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W678394. | |
| DOTA-tris(tBu)ester NHS ester | DOTA-tris(tBu)ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris(tBu)ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 819869-77-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-131326. | |
| DOTA-tris(tert-butyl ester) | It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Alternative Names: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate; DOTA tri(tert-butyl) ester; DOTA(OBu-t)3; Tri-tert-Bu-DOTA; 2-(4,7,10-Tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; DOTA(OtBu); 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-dimethylethyl) ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-tris-tert-butyl acetate-10-acetic acid. Grades: 95%. CAS No. 137076-54-1. Molecular formula: C28H52N4O8. Mole weight: 572.73. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137076-54-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W034551. | |
| DOTA-tri(t-butyl ester) | DOTA-tri(t-butyl ester). Alternative Names: Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate. CAS No. 137076-54-1. Purity: ≥99%. Product ID: ACM137076541-3. Molecular formula: C28H52N4O8. Mole weight: 572.73. Alfa Chemistry - ISO 9001:32057 Certified. | |
| DOTC Perchlorate | DOTC Perchlorate, or dodecyltrimethoxysilane perchlorate, is a multifaceted chemical compound with diverse applications. Its versatility is evident in its role as a catalyst in organic synthesis, where it contributes significantly to the preparation of silane-modified polymers and the functionalization of surfaces. Moreover, this compound serves as a pivotal coupling agent in the manufacturing of adhesives, sealants, and coatings, enhancing their adhesion and durability. The intrinsic properties of DOTC Perchlorate underscore its indispensability in various industrial processes, rendering it an indispensable component in the production of a wide array of materials. Alternative Names: 3-ethyl-2-[7-(3-ethyl-2(3H)-benzoxazolylidene)-1,3,5-heptatrienyl]-benzoxazolium perchlorate; 3,3'-diethyl-2,2'-oxatricarbocyanine perchlorate. Molecular formula: C25H25N2O2?ClO4. Mole weight: 484.936. | |
| Dothiepin | A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-. Grades: Highly Purified. CAS No. 113-53-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Dothiepin | Dothiepin (Dosulepin; Dothep) is an antidepressant agent with sedative/anxiolytic activity. Dothiepin is an inhibitor preferring of noradrenaline uptake than serotonin uptake. Dothiepin facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. Dothiepin is also an antagonist of histamine H1-receptor without cardiotoxicity. Dothiepin exhibits significant analgesic activity in psychogenic facial pain, idiopathic fibromyalgia syndrome or rheumatoid arthritis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dosulepin; Dothep. CAS No. 113-53-1. Pack Sizes: 1 mg. Product ID: HY-12394. | |
| Dothiepin-d3 | Labeled Dothiepin. A tricyclic antidepressant. Group: Biochemicals. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-. Grades: Highly Purified. CAS No. 136765-31-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Dotinurad Impurity 1 | Dotinurad Impurity 1. Uses: For analytical and research use. CAS No. 3336-41-2. Molecular formula: C7H4Cl2O3. Mole weight: 207.01. Catalog: APB3336412. | |
| Dotinurad Impurity 10 | Dotinurad Impurity 10. Uses: For analytical and research use. Molecular formula: C15H11Cl2NO4S. Mole weight: 372.22. Catalog: APB12096. | |
| Dotinurad Impurity 11 | Dotinurad Impurity 11. Uses: For analytical and research use. Molecular formula: C21H11Cl4NO6S. Mole weight: 547.18. Catalog: APB12095. | |
| Dotinurad Impurity 12 | Dotinurad Impurity 12. Uses: For analytical and research use. Molecular formula: C21H12Cl3NO5S. Mole weight: 496.74. Catalog: APB12097. | |
| Dotinurad Impurity 2 | Dotinurad Impurity 2. Uses: For analytical and research use. CAS No. 37908-97-7. Molecular formula: C8H6Cl2O3. Mole weight: 221.03. Catalog: APB37908977. | |
| Dotinurad Impurity 3 | Dotinurad Impurity 3. Uses: For analytical and research use. CAS No. 29568-76-1. Molecular formula: C8H5Cl3O2. Mole weight: 239.48. Catalog: APB29568761. | |
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