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| Product | Description | |
|---|---|---|
| DOPG | DOPG is a phosphatidylglycerol in which the phosphatidyl acyl groups are both oleoyl. It has been used to physically stabilize emulsions and suspensions. It is also used in formulations of pulmonary surfactants, intravenous fat emulsions, and oral solutions. Alternative Names: Dioleoyl phosphatidylglycerol; 1,2-Dioctadecenoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; C18:1 phosphatidylglycerol; C18:1 PG; DOPG; 3-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-2-[(9Z)-octadec-9-enoyloxy]propyl (9Z)-octadec-9-enoate. Grades: ≥95% by HPLC. CAS No. 62700-69-0. Molecular formula: C42H79O10P. Mole weight: 775.04. |  |
| DOPG:DOPC (40:60) Anionic Liposomes | In PG-based anionic liposomes, its zeta potential depends on the mole percent of negatively charged PG in the liposome formulation. We provide anionic liposomes with different DOPG contents, which have different amounts of negative Zeta potential. Uses: Anionic liposomes are used in blood complement research and various types of in vitro research. | |
| DOPG sodium | DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dioleoylphosphatidylglycerol sodium. CAS No. 67254-28-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141571. |  |
| D-O-Phospho threonine | D-O-Phospho threonine. Group: Biochemicals. Alternative Names: D-Threonine dihydrogen phosphate(ester); D-O-Phosphothreonine. Grades: Highly Purified. CAS No. 96193-69-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C4H10NO6P. US Biological Life Sciences. |  Worldwide |
| DOPS | DOPS (1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium salt) is high purity phospholipid utilized for liposome production. Alternative Names: (2S,8R,19Z)-2-amino-5-hydroxy-11-oxo-8-[[(9Z)-1-oxo-9-octadecenyl]oxy]-4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 5-oxide, monosodium salt; L-α-Phosphatidyl-L-serine, dioleoyl sodium salt; 1,2-Dioleoyl-sn-Glycero-3-Phosphatidylserine Na salt; 18:1 PS. Grades: >98%. CAS No. 90693-88-2. Molecular formula: C42H77NO10P; Na. Mole weight: 810.03. | |
| DOPS Anionic Liposomes | The amount of negative zeta potential in liposomes depends on the mole percent of phosphatidylserine (PS). Liposomes containing different proportions of PS have different numbers of negative zeta potentials. The use of DOPC does not significantly increase the charge of the liposomes. Uses: Anionic liposomes are used in blood complement research and various types of in vitro research. | |
| DOPS:DOPC (10:90) Anionic Liposomes | The amount of negative zeta potential in liposomes depends on the mole percent of phosphatidylserine (PS). Liposomes containing different proportions of PS have different numbers of negative zeta potentials. The use of DOPC does not significantly increase the charge of the liposomes. Uses: Anionic liposomes are used in blood complement research and various types of in vitro research. | |
| Doramapimod | Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIRB 796. CAS No. 285983-48-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10320. | |
| Doramapimod | Doramapimod is a highly potent inhibitor of p38 mitogen-activated protein kinase (MAPK). Doramapimod is a potential agent for the treatment of inflammatory diseases. Doramapimod blocks baseline and bortezomib-triggered upregulation of p38 MAPK and Hsp27 phosphorylation leading to enhanced cytotoxicity and caspase activation. Group: Biochemicals. Alternative Names: N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea; BIRB 796BS; Birb 796. Grades: Highly Purified. CAS No. 285983-48-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Doramapimod (BIRB 796) | Doramapimod (BIRB 796) is a pan-p38 MAPK inhibitor with IC50 of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38α with Kd of 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2. Group: Inhibitors. CAS No. 285983-48-4. Pack Sizes: 5mg. Product ID: S1574. Formula: C31H37N5O3. Smiles: CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=CC=C(C4=CC=CC=C43)OCCN5CCOCC5. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Doramapimod hydrochloride | Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-α and IL-1β induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIRB 796 hydrochloride. CAS No. 1283526-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10320A. | |
| Doramectin | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C50H74O14. CAS No. 117704-25-3. Prepack ID 48672805-1g. Molecular Weight 899.11. See USA prepack pricing. |  |
| Doramectin | Doramectin is a derivative of ivermectin, which is an anthelmintic. Doramectin is an antiparasitic antibiotic produced by Streptomyces. Alternative Names: UK67994. Grades: 95%. CAS No. 117704-25-3. Molecular formula: C50H74O14. Mole weight: 899.11. | |
| Doramectin | Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin / avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. Group: Biochemicals. Grades: Highly Purified. CAS No. 117704-25-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Doramectin aglycone | It is an acid degradation product produced by hydrolysis of the disaccharide unit of doramectin. It is an inhibitor of nematode larval development and an anthelmintic in animal health. It has no paralytic activity. Alternative Names: 25R-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6R,28-epoxy-13S-hydroxy-milbemycin B. Grades: >95% by HPLC. CAS No. 1987883-26-0. Molecular formula: C36H50O8. Mole weight: 610.78. | |
| Doramectin Impurity 1 | Doramectin Impurity 1. Uses: For analytical and research use. Molecular formula: C50H76O15. Mole weight: 917.13. Catalog: APB05513. |  |
| Doramectin Impurity 2 | Doramectin Impurity 2. Uses: For analytical and research use. Alternative Names: Doramectin Impurity 2. CAS No. 65195-56-4. Molecular formula: C47H70O14. Mole weight: 859.05. Catalog: APB65195564. | |
| Doramectin Impurity 3 | Doramectin Impurity 3. Uses: For analytical and research use. Alternative Names: Doramectin Impurity 3. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08. Catalog: APB65195553. | |
| Doramectin Impurity 4 | Doramectin Impurity 4. Uses: For analytical and research use. Molecular formula: C50H76O14. Mole weight: 901.13. Catalog: APB05512. | |
| Doramectin Impurity 5 | Doramectin Impurity 5. Uses: For analytical and research use. Molecular formula: C49H72O14. Mole weight: 885.09. Catalog: APB05511. | |
| Doramectin Impurity 6 | Doramectin Impurity 6. Uses: For analytical and research use. Molecular formula: C50H74O14. Mole weight: 899.11. Catalog: APB05509. | |
| Doramectin Impurity 7 | Doramectin Impurity 7. Uses: For analytical and research use. Molecular formula: C51H76O14. Mole weight: 913.14. Catalog: APB05510. | |
| Doramectin monosaccharide | It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of doramectin. It is a potent inhibitor of nematode larval development and an anthelmintic in animal health. Alternative Names: 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a. Grades: >95% by HPLC. CAS No. 165108-44-1. Molecular formula: C43H62O11. Mole weight: 754.95. | |
| Doravirine | Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-1439. CAS No. 1338225-97-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16767. | |
| Doravirine | Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going. Uses: Hiv-1 infections. Alternative Names: MK-1439; MK 1439; MK1439; MK-1439-019;3-Chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile. Grades: 98%. CAS No. 1338225-97-0. Molecular formula: C17H11ClF3N5O3. Mole weight: 425.75. | |
| Doravirine | Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor used for the treatment of HIV/AIDS. Category: Active pharmaceutical ingredients. CAS No. 1338225-97-0. Product ID: API1338225970. Molecular formula: C17H11ClF3N5O3. Mole weight: 425.75. |  |
| Doravirine-[13C6] | Labelled Doravirine. Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going. Alternative Names: 3-Chloro-5-[[1-[(4,5-dihydro-4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile-13C6. Grades: 98%; 99% atom 13C. Molecular formula: C11[13C]6H11ClF3N5O3. Mole weight: 431.71. | |
| Dordaviprone | Dordaviprone (TIC10) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. Dordaviprone can cross the blood-brain barrier[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TIC10; ONC-201. CAS No. 1616632-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15615A. | |
| Doremoxยฎ | Doremoxยฎ. CAS No. 94201-73-7. VIGON Item # 502910. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, Rose Pyran. |  America & Internationally |
| Doripenem | Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S 4661. CAS No. 148016-81-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0187. | |
| Doripenem | Antibacterial agent. Group: Biochemicals. Alternative Names: (4R, 5S, 6S) -3-[[ (3S, 5S) -5-[[ (Aminosulfonyl) amino]methyl]-3-pyrrolidinyl]thio]-6-[ (1R) -1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3. 2. 0]hept-2-ene-2-carboxylic Acid;S 4661. Grades: Highly Purified. CAS No. 148016-81-3. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C15H24N4O6S2. US Biological Life Sciences. | Worldwide |
| Doripenem | 100mg Pack Size. Group: Antibiotics, Biochemicals, Research Organics & Inorganics. Formula: C15H24N4O6S2. CAS No. 148016-81-3. Prepack ID 14558613-100mg. Molecular Weight 420.51. See USA prepack pricing. | |
| Doripenem Dimer | Doripenem Dimer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C30H48N8O12S4. US Biological Life Sciences. | Worldwide |
| Doripenem hydrate | Doripenem hydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 364622-82-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Doripenem hydrate | Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections. Alternative Names: S-4661; S 4661; S4661. Grades: >98%. CAS No. 364622-82-2. Molecular formula: C15H24N4O6S2.H2O. Mole weight: 438.52. | |
| Doripenem hydrate | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C15H24N4O6S2 ยท H2O. CAS No. 364622-82-2. Prepack ID 36359573-1g. Molecular Weight 438.52. See USA prepack pricing. | |
| Doripenem Impurity 1 | Doripenem Impurity 1. Uses: For analytical and research use. Alternative Names: (2S,4S)-4-nitrobenzyl 4-(acetylthio)-2-(aminomethyl)pyrrolidine-1-carboxylate. Molecular formula: C15H19N3O5S. Mole weight: 353.39. Catalog: APB05270. | |
| Doripenem Impurity 11 | Doripenem Impurity 11. Uses: For analytical and research use. CAS No. 1233517-79-7. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB1233517797. | |
| Doripenem Impurity 12 | Doripenem Impurity 12. Uses: For analytical and research use. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB10447. | |
| Doripenem Impurity 13 | Doripenem Impurity 13. Uses: For analytical and research use. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB10448. | |
| Doripenem Impurity 2 | Doripenem Impurity 2. Uses: For analytical and research use. CAS No. 396717-61-6. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB396717616. | |
| Doripenem Impurity 3 | Doripenem Impurity 3. Uses: For analytical and research use. CAS No. 958879-77-1. Molecular formula: C10H17NO4S. Mole weight: 247.31. Catalog: APB958879771. | |
| Doripenem Impurity 4 | Doripenem Impurity 4. Uses: For analytical and research use. CAS No. 571176-82-4. Molecular formula: C21H30N4O9S2. Mole weight: 546.61. Catalog: APB571176824. | |
| Doripenem Impurity 5 (Methyl Acetoacetate) | Doripenem Impurity 5 (Methyl Acetoacetate). Uses: For analytical and research use. CAS No. 105-45-3. Molecular formula: C5H8O3. Mole weight: 116.12. Catalog: APB105453. | |
| Doripenem Impurity 6 | Doripenem Impurity 6. Uses: For analytical and research use. CAS No. 90776-59-3. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB90776593. | |
| Doripenem Impurity 7 | Doripenem Impurity 7. Uses: For analytical and research use. CAS No. 189188-38-3. Molecular formula: C29H27N2O10P. Mole weight: 594.51. Catalog: APB189188383. | |
| Doripenem Polymer Impurity | Doripenem Polymer Impurity. Uses: For analytical and research use. CAS No. 491878-07-0. Molecular formula: C30H34N6O12S2. Mole weight: 734.75. Catalog: APB491878070. | |
| Doripenem side-chain | Doripenem side-chain. Group: Biochemicals. Alternative Names: 4-Nitrobenzyl (2S, 4S) -4-acetylthio-2- [ [N-sulfamoyl-N- (tert-butoxycarbonyl) amino] methyl] pyrrolidine-1-carboxylate. Grades: Highly Purified. CAS No. 491878-06-9. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Dornase alfa | Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rhDNase. CAS No. 143831-71-4. Pack Sizes: 500 μg. Product ID: HY-108858. | |
| D-Ornithine | D-Ornithine. Alternative Names: (R)-ornithine. CAS No. 348-66-3. Molecular formula: C5H12N2O2. Mole weight: 132.16. | |
| D-ornithine 4,5-aminomutase | A pyridoxal-phosphate protein that requires a cobamide coenzyme for activity. Group: Enzymes. Synonyms: D-α-ornithine 5,4-aminomutase; D-ornithine aminomutase. Enzyme Commission Number: EC 5.4.3.5. CAS No. 62213-30-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5537; D-ornithine 4,5-aminomutase; EC 5.4.3.5; 62213-30-3; D-α-ornithine 5,4-aminomutase; D-ornithine aminomutase. Cat No: EXWM-5537. |  |
| D-Ornithine hydrochloride | D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-Ornithine hydrochloride. CAS No. 16682-12-5. Pack Sizes: 10 mM * 1 mL in Water; 1 g; 5 g; 10 g; 25 g. Product ID: HY-34516. | |
| D-Ornithine hydrochloride | D-Ornithine hydrochloride. Group: Biochemicals. Alternative Names: (R)-Ornithine hydrochloride; (R)-2,5-Diaminopentanoic acid hydrochloride; D-Ornithine monohydrochloride. Grades: Highly Purified. CAS No. 16682-12-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H13ClN2O2. US Biological Life Sciences. | Worldwide |
| D-Ornithine hydrochloride 99+% | D-Ornithine hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| D-Ornithine monohydrochloride | D-Ornithine monohydrochloride. Alternative Names: D-Ornithine, hydrochloride (1:1); D-Ornithine, hydrochloride; Ornithine, monohydrochloride, D-; (2R)-2,5-Diaminopentanoic acid monohydrochloride; (R)-Ornithine hydrochloride; D-Orn-OH HCl; (R)-2,5-diaminopentanoic acid monohydrochloride. Grades: ≥95%. CAS No. 16682-12-5. Molecular formula: C5H12N2O2.HCl. Mole weight: 168.62. | |
| Dorrigocin A | It is produced by the strain of Streptomyces platensis subsp. rosaceus AB-1981F-75. It has weak anti-tumor cell activity and moderate anti-aspergillus and fusarium activity, but has no effect on yeast. Dorrigocin B has stronger antitumor and antifungal activities than Dorrigocin A. It can restore the morphology of RAS-deformed NIH/3T3 cells from the deformed phenotype to the normal phenotype. CAS No. 158446-29-8. Molecular formula: C27H41NO8. Mole weight: 507.61. | |
| Dorrigocin B | It is produced by the strain of Streptomyces platensis subsp. rosaceus AB-1981F-75. It has weak anti-tumor cell activity and moderate anti-aspergillus and fusarium activity, but has no effect on yeast. Dorrigocin B has stronger antitumor and antifungal activities than Dorrigocin A. It can restore the morphology of RAS-deformed NIH/3T3 cells from the deformed phenotype to the normal phenotype. CAS No. 158446-30-1. Molecular formula: C27H41NO8. Mole weight: 507.61. | |
| Dorsomorphin | Dorsomorphin. Group: Biochemicals. Alternative Names: Compound C, AMPK Inhibitor, BML-275, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine. Grades: Highly Purified. CAS No. 866405-64-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C24 H25 N5, Molecular Weight: 399.5. US Biological Life Sciences. | Worldwide |
| Dorsomorphin | Dorsomorphin is a potent and selective inhibitor of AMPK (AMP-activated protein kinase) (Ki = 109 nM), induced by AICAR and metformin. It also inhibits bone morphogenetic protein (BMP) receptors including BMPR-IA (ALK3) and BMPR-IB (ALK6). Dorsomorphin can induce myocardial differentiation in mouse embryonic stem cells (mESCs). Uses: Protein kinase inhibitors. Alternative Names: 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine; Compound C; AMPK Inhibitor, Compound C; BML-275. Grades: >98%. CAS No. 866405-64-3. Molecular formula: C24H25N5O. Mole weight: 399.49. | |
| Dorsomorphin | Dorsomorphin Inhibitor. Uses: Scientific use. Product Category: T1977. CAS No. 866405-64-3. |  |
| Dorsomorphin | Dorsomorphin (Compound C) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Compound C; BML-275. CAS No. 866405-64-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13418A. | |
| Dorsomorphin 2HCl | Dorsomorphin (hydrochloride) is a potent, reversible inhibitor of AMP kinase (AMPK; Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. CAS No. 1219168-18-9. Molecular formula: C24H25N5O.2HCl. Mole weight: 472.414. | |
| Dorsomorphin (Compound C) | Dorsomorphin is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin selectively inhibits the BMP type I receptors ALK2, ALK3 and ALK6. Dorsomorphin is used in promoting specific cell differentiation and inducing cancer cell line autophagy. For cell testing, the water-soluble S7306 Dorsomorphin 2HCl is recommended. Group: Inhibitors. Alternative Names: BML-275,Compound C. CAS No. 866405-64-3. Pack Sizes: 5mg. Product ID: S7840. Formula: C24H25N5O. Smiles: C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Dorsomorphin dihydrochloride | Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Compound C dihydrochloride; BML-275 dihydrochloride. CAS No. 1219168-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13418. | |
| Dorsomorphin Dihydrochloride | Dorsomorphin 2HCl is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits type 1 BMP receptor activity. Dorsomorphin induces autophagy in cancer cell line. Group: Inhibitors. Alternative Names: BML-275 2HCl,Compound C 2HCl. CAS No. 1219168-18-9. Pack Sizes: 10mg. Product ID: S7306. Formula: C24H25N5O.2HCl. Smiles: C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Dorsomorphin dihydrochloride (GMP) | Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418). GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Compound C dihydrochloride (GMP); BML-275 dihydrochloride (GMP). CAS No. 1219168-18-9. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13418G. | |
| Dorzagliatin | Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMS5552. CAS No. 1191995-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109030. | |
| Dorzolamide | Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4S,6S)-. Grades: Highly Purified. CAS No. 130693-82-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Dorzolamide-[d5] | Dorzolamide-[d5] is the labelled analogue of Dorzolamide. Dorzolamide is a carbonic anhydrase inhibitor used to lower the pressure of eyes with glaucoma. Alternative Names: Dorzolamide D5; (4S,6S)-4-[(2H5)Ethylamino]-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide. Grades: 95% by HPLC; 95% atom D. CAS No. 1227097-70-2. Molecular formula: C10H11D5N2O4S3. Mole weight: 329.47. | |
| Dorzolamide EP Impurity A (Hydrochloride) | Dorzolamide EP Impurity A (Hydrochloride). Uses: For analytical and research use. Alternative Names: (4R,6R)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride. CAS No. 122028-36-8. Molecular formula: C10H17ClN2O4S3. Mole weight: 360.90. Catalog: APB122028368. | |
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