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| Product | Description | |
|---|---|---|
| D-myo-Inositol-1,4,5-triphosphate trisodium | D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Inositol 1,4,5-trisphosphate trisodium; Ins(1,4,5)-P3 trisodium. CAS No. 141611-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-103642A. |  |
| D-myo-Inositol 1,4,5-trisphosphate Trisodium Salt | D-myo-Inositol 1,4,5-Tris-phosphate Trisodium Salt is used in the preparation of optically active compounds that functions as second messenger in a new intracellular signal transduction systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 141611-10-1. Pack Sizes: 500ug, 1mg. Molecular Formula: C6H12Na3O15P3, Molecular Weight: 486.04. US Biological Life Sciences. |  Worldwide |
| D-myo-Inositol 1,4,6-triphosphate sodium salt | D-myo-Inositol 1,4,6-triphosphate sodium salt is an extensively refined chemical compound employed in the biomedical sector assuming the role of an intracellular messenger, orchestrating intricate cellular processes, namely, cell growth and calcium signaling. It manifests pivotal significance in the research of maladies associated with the dysregulation of inositol phosphate pathways, encompassing select cancers, neurodegenerative disorders and metabolic irregularities. Synonyms: Ins(1,4,6)-P3 (sodium salt); 1,4,6-IP3 (sodium salt). CAS No. 157380-18-2. Molecular formula: C6H12O15P3.xNa. Mole weight: 417.07 (free acid basis). |  |
| D-myo-Inositol-1,5,6-triphosphate sodium salt | D-myo-Inositol-1,5,6-triphosphate sodium salt is a fundamental compound prominently employed sector assuming an indispensable character within cellular signal transduction pathways, orchestrating sundry physiological processes. This prodigious entity operates as a secondary courier is adroitly overseeing calcium levels and intricately modulating multifarious cellular functionalities. Synonyms: 1,5,6-IP3 sodium salt; Ins(1,5,6)-P3 sodium salt; D-myo-Inositol, 1,2,6-tris(dihydrogen phosphate), sodium salt; D-Ins(1,2,6)P3 sodium salt; D-myo-1,2,6-Inositol trisphosphate sodium salt; D-myo-Inositol 1,2,6-triphosphate sodium salt; Atrinositol sodium salt; PP 56 sodium salt; α-Trinositol sodium salt. CAS No. 120965-76-6. Molecular formula: C6H15O15P3.xNa. Mole weight: 420.10 (free acid). | |
| D-myo-Inositol-2,3,5,6-tetraphosphate sodium salt | D-myo-inositol-2,3,5,6-tetraphosphate sodium salt is produced from Ins(1,2,3,5,6)P5 by a minor enzymatic phytate degradation pathway. And it is moderately effective in opening calcium channels than Ins(1,4,5)P3. Synonyms: 2,3,5,6-IP4 sodium salt; Ins(2,3,5,6)-P4 sodium salt; D-myo-inositol-2,3,5,6-tetrakis(dihydrogen phosphate), tetrasodium salt. Grade: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-2,3,5-triphosphate ammonium salt | D-myo-Inositol-2,3,5-triphosphate ammonium salt is a member of the inositol phosphate (InsP) family of second messengers which play an important role in the transmission of cellular signals. Ins(2,3,5)P3 ammonium salt is 500-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes. Synonyms: Ins(2,3,5)P3 ammonium salt; 2,3,5-IP3 ammonium salt; D-myo-inositol-2,3,5-tris(dihydrogen phosphate), triammonium salt. Grade: ≥98%. Molecular formula: C6H12O15P3·3NH4. Mole weight: 522.3. | |
| D-myo-Inositol-2,3-O-cyclohexylidene | D-myo-Inositol-2,3-O-cyclohexylidene exhibits inhibitory efficacy in studyting a myriad of ailments such as diabetes, polycystic ovary syndrome (PCOS) and metabolic irregularities. Synonyms: hexahydrospiro[1,3-benzodioxole-2,1'-cyclohexane]-4,5,6,7-tetrol; Hexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-4,5,6,7-tetraol; spiro[3a,4,5,6,7,7a-hexahydro-1,3-benzodioxole-2,1'-cyclohexane]-4,5,6,7-tetrol; spiro(2,4-dioxabicyclo[4.3.0]nonane-3,1'-cyclohexane)-6,7,8,9-tetrol. CAS No. 57029-87-5. Molecular formula: C12H20O6. Mole weight: 260.28. | |
| D-myo-Inositol-2,4,5-triphosphate sodium salt | D-myo-Inositol-2,4,5-triphosphate sodium salt is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3. Synonyms: Ins(2,4,5)P3 sodium salt; 2,4,5-IP3 sodium salt; D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt. Grade: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-myo-Inositol-2,5,6-triphosphate sodium salt | Ins(2,5,6)P3 is a less potent inducer of calcium release from permeabilized rat basophilic leukemia cells with an EC50 value of 110 μM compared to Ins(1,4,5)P3, which has an EC50 value of 0.17 μM. Synonyms: Ins(2,5,6)P3 sodium salt; 2,5,6-IP3 sodium salt; D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt. Grade: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-myo-Inositol-3,4,5,6-tetraphosphate sodium salt | D-myo-Inositol-3,4,5,6-tetraphosphate sodium salt is one of several different inositol oligophosphate isomers implicated in signal transduction. It almost completely inhibits calcium-activated chloride channels at a concentration of 8-10 μM. And it was found to be inactive when analyzed for Ca2+-releasing potency in Xenopus oocytes. Synonyms: Ins(3,4,5,6)-P4; 3,4,5,6-IP4; D-myo-inositol-3,4,5,6-tetra(hydrogen phosphate), tetrasodium salt. Grade: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588. | |
| D-myo-Inositol-3,4,5-triphosphate | D-myo-Inositol-3,4,5-triphosphate is an indispensable molecule in the biomedical field, serving as a pivotal second messenger within intracellular signaling pathways, imposing control over calcium homeostasand intricate cellular mechanisms. Its significance lies in orchestrating critical processes, encompassing cellular proliferation, specialization and programmed cell death. The utilization of D-myo-Inositol-3,4,5-triphosphate prevails prominently in research endeavors and pharmaceutical advancements, with a primary focus on comprehending signal transduction, unraveling the complexities of neoplastic disorders and exploring promising therapeutic modalities. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4. CAS No. 112791-62-5. Molecular formula: C6H15O15P3. Mole weight: 420.10. | |
| D-myo-Inositol-3,4,5-triphosphate sodium salt | D-myo-Inositol-3,4,5-triphosphate (Ins(3,4,5)-P3) is a structural analog of Ins(1,4,5)-P3 and also a member of the inositol phosphate (InsP) cell signaling family of molecules. D-myo Ins(3,4,5)-P3 is 200-fold less potent than D-myo Ins(1,4,5)-P3 at initiating Ca++ release when injected into Xenopus oocytes. Ins(3,4,5)-P3 binds to Type 1, 2, and 3 subtypes of the rat recombinant IP3 receptor with Ki values of 3-11 μM. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4; D-myo-inositol-3,4,5-tris(hydrogen phosphate), trisodium salt. Grade: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486. | |
| D-myo-inositol 3-phosphate | D-myo-inositol 3-phosphate is an essential molecular compound extensively utilized in the research of diverse afflictions including Alzheimer's disease, depression and diabetes. Synonyms: Inositol 3-phosphate; 1D-myo-inositol 3-phosphate; L-myo-inositol 1-phosphate; 1L-myo-inositol 1-phosphate; D-myo-Inositol 3-monophosphate; 1D-myo-inositol 3-monophosphate; Inositol 3-monophosphate; myo-Inositol 3-phosphate; myo-Inositol 3-monophosphate; Myoinositol 3-phosphate; myo-Inositol-1-phosphate; LIP; Inositol-1-phosphate, myo-; 1L-myo-inositol 1-(dihydrogen phosphate); {[(2S,3R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphonic acid. CAS No. 2831-74-5. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| D-myo-Inositol-3-phosphate (sodium salt) | D-myo-Inositol-3-phosphate (sodium salt) is the second messenger of the inositol phosphate molecular family, which plays a key role in the transmission of cellular signals. It can be formed by dephosphorylation of polyphosphate inositols such as Ins(3,4)P2 by inositol polyphosphate 4-phosphatase. Synonyms: 3-IP1 (sodium salt); Ins(3)P1 (sodium salt); 1,2,3,4,5,6-Cyclohexanehexol, 1-(dihydrogen phosphate), sodium salt, (1α,2α,3α,4β,5α,6β)- (1:1); D-myo-inositol-3-hydrogen phosphate, monosodium salt. Grade: ≥95%. Molecular formula: C6H12NaO9P. Mole weight: 282.12. | |
| DN02 | DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8 (1) (Ki=32 nM), which is 30-fold more affinity than BRD8 (2) (Ki>1000 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055009-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148116. | |
| DN-1289 | DN-1289 is an orally active and selective inhibitor of dual leucine zipper kinase (DLK; IC50=17 nM) and leucine zipper-bearing kinase (LZK; IC50=40 nM). DN-1289 results significant attenuation of optic nerve crush (ONC)-induced p-c-Jun in mice model. DN-1289 has excellent in vivo plasma half-life and blood-brain barrier permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3026597-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152142. | |
| DNA2 inhibitor C5 | DNA2 inhibitor C5 is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits the nuclease, DNA-dependent ATPase, helicase, and DNA-binding activities of DNA2. DNA2 inhibitor C5 can be used in breast cancer and colorectal cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35973-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128729. | |
| DNA31 | DNA31 is a potent inhibitor of RNA polymerase. Synonyms: Rifamycin VIII, 5'-(4-amino-1-piperidinyl)-1',4-didehydro-1-deoxy-1,4-dihydro-3'-hydroxy-1-oxo-. Grade: ≥95%. CAS No. 845626-57-5. Molecular formula: C48H58N4O13. Mole weight: 898.99. | |
| DNA-3-methyladenine glycosylase I | Involved in the removal of alkylated bases from DNA in Escherichia coli (cf. EC 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase). Group: Enzymes. Synonyms: deoxyribonucleate 3-methyladenine glycosidase I; 3-methyladenine DNA glycosylase I; DNA-3-methyladenine glycosidase I. Enzyme Commission Number: EC 3.2.2.20. CAS No. 89287-37-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3974; DNA-3-methyladenine glycosylase I; EC 3.2.2.20; 89287-37-6; deoxyribonucleate 3-methyladenine glycosidase I; 3-methyladenine DNA glycosylase I; DNA-3-methyladenine glycosidase I. Cat No: EXWM-3974. |  |
| DNA-3-methyladenine glycosylase II | Involved in the removal of alkylated bases from DNA in Escherichia coli (cf. EC 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase). Group: Enzymes. Synonyms: deoxyribonucleate 3-methyladenine glycosidase II; 3-methyladenine DNA glycosylase II; DNA-3-methyladenine glycosidase II; AlkA. Enzyme Commission Number: EC 3.2.2.21. CAS No. 89287-38-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3975; DNA-3-methyladenine glycosylase II; EC 3.2.2.21; 89287-38-7; deoxyribonucleate 3-methyladenine glycosidase II; 3-methyladenine DNA glycosylase II; DNA-3-methyladenine glycosidase II; AlkA. Cat No: EXWM-3975. | |
| DNA α-glucosyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: uridine diphosphoglucose-deoxyribonucleate α-glucosyltransferase; UDP-glucose-DNA α-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate α-glucosyltransferase; T2-HMC-α-glucosyl transferase; T4-HMC-α-glucosyl transferase; T6-HMC-α-glucosyl transferase. Enzyme Commission Number: EC 2.4.1.26. CAS No. 9030-13-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2490; DNA α-glucosyltransferase; EC 2.4.1.26; 9030-13-1; uridine diphosphoglucose-deoxyribonucleate α-glucosyltransferase; UDP-glucose-DNA α-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate α-glucosyltransferase; T2-HMC-α-glucosyl transferase; T4-HMC-α-glucosyl transferase; T6-HMC-α-glucosyl transferase. Cat No: EXWM-2490. | |
| DNA-(apurinic or apyrimidinic site) lyase | Nicking of the phosphodiester bond is due to a lyase-type reaction, not hydrolysis. This group of enzymes was previously listed as endonucleases, under EC 3.1.25.2. Group: Enzymes. Synonyms: AP lyase; AP endonuclease class I; endodeoxyribonuclease (apurinic or apyrimidinic); deoxyribonuclease (apurinic or apyrimidinic); E. coli endonuclease III; phage-T4 UV endonuclease; Micrococcus luteus UV endonuclease; AP site-DNA 5'-phosphomonoester-lyase; X-ray endonuclease III. Enzyme Commission Number: EC 4.2.99.18. CAS No. 61811-29-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5265; DNA-(apurinic or apyrimidinic site) lyase; EC 4.2.99.18; 61811-29-8; AP lyase; AP endonuclease class I; endodeoxyribonuclease (apurinic or apyrimidinic); deoxyribonuclease (apurinic or apyrimidinic); E. coli endonuclease III; phage-T4 UV endonuclease; Micrococcus luteus UV endonuclease; AP site-DNA 5'-phosphomonoester-lyase; X-ray endonuclease III. Cat No: EXWM-5265. | |
| DNA β-glucosyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: T4-HMC-β-glucosyl transferase; T4-β-glucosyl transferase; T4 phage β-glucosyltransferase; UDP glucose-DNA β-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate β-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.27. CAS No. 9030-14-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2501; DNA β-glucosyltransferase; EC 2.4.1.27; 9030-14-2; T4-HMC-β-glucosyl transferase; T4-β-glucosyl transferase; T4 phage β-glucosyltransferase; UDP glucose-DNA β-glucosyltransferase; uridine diphosphoglucose-deoxyribonucleate β-glucosyltransferase. Cat No: EXWM-2501. | |
| DNA-binding protein RFX6 (414-431) | DNA-binding protein RFX6 (414-431) is a truncated fragment of DNA-binding protein RFX6. DNA-binding protein RFX6 is a transcription factor required to direct islet cell differentiation during endocrine pancreas development. Synonyms: Regulatory factor X 6 (414-431); Regulatory factor X domain-containing protein 1 (414-431). | |
| D-N-Acetylgalactosamine | D-N-Acetylgalactosamine is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 1811-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-33212. | |
| DNA (cytosine-5-)-methyltransferase | This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. Group: Enzymes. Synonyms: EcoRI methylase; DNA 5-cytosine methylase; DNA cytosine C5 methylase; DNA cytosine methylase; DNA methylase (ambiguous); DNA methyltransferase (ambiguous); DNA transmethylase (ambiguous); DNA-cytosine 5-methylase; DNA-cytosine methyltransferase; HpaII methylase; HpaII' methylase; M.BsuRIa; M.BsuRIb; Type II DNA methylase; cytosine 5-methyltransferase; cytosine DNA methylase; cytosine DNA methyltransferase; cytosine-specific D. Enzyme Commission Number: EC 2.1.1.37. CAS No. 9037-42-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1940; DNA (cytosine-5-)-methyltransferase; EC 2.1.1.37; 9037-42-7; EcoRI methylase; DNA 5-cytosine methylase; DNA cytosine C5 methylase; DNA cytosine methylase; DNA methylase (ambiguous); DNA methyltransferase (ambiguous); DNA transmethylase (ambiguous); DNA-cytosine 5-methylase; DNA-cytosine methyltransferase; HpaII methylase; HpaII' methylase; M.BsuRIa; M.BsuRIb; Type II DNA methylase; cytosine 5-methyltransferase; cytosine DNA methylase; cytosine DNA methyltransferase; cytosine-specific DNA methyltransferase; deoxyribonucleate methylase (ambiguous); deoxyribonucleate methyltransferase (. | |
| DNA Damage and Repair Compound Library Plus | Quantity: well-chosen 667 compounds with unique structures targeting DNA damage & repair; - High bioactivity: All compounds with IC50 below 3 μM; - Targets included 19 DNA damage & repair related proteins; - Detailed information: each compound has information about activity testing method, providing reference for your experimental design; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for DNA damage/repair targeting drug development and target identification. Uses: Scientific use. Product Category: L3980. Categories: DNA Damage and Repair Compounds Libraries Plus. |  |
| DNA Damage & Repair Compound Library | A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3900. Categories: DNA Damage & Repair Compounds Libraries. | |
| DNA,d(C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A), 5'-ester with1,2-ethanediylbis(oxy-2,1-ethanediyl)bis[2-(21,21-dihydroxy-21-oxido-4,11-dioxo-20-oxa-13-thia-3,10-diaza-21-phosphaheneicos-1-yl)-23,23-di | DNA,d(C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A), 5'-ester with1,2-ethanediylbis(oxy-2,1-ethanediyl)bis[2-(21,21-dihydroxy-21-oxido-4,11-dioxo-20-oxa-13-thia-3,10-diaza-21-phosphaheneicos-1-yl)-23,23-di. CAS No. 167362-48-3. Product ID: ACM167362483. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| DNA-deoxyinosine glycosylase | DNA-deoxyinosine glycosylase (EC 3.2.2.15) is an enzyme with systematic name DNA-deoxyinosine deoxyribohydrolase. Group: Enzymes. Synonyms: DNA(hypoxanthine) glycohydrolase; deoxyribonucleic acid glycosylase; hypoxanthine-DNA glycosylase. Enzyme Commission Number: EC 3.2.2.15. CAS No. 68247-62-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3969; DNA-deoxyinosine glycosylase; EC 3.2.2.15; 68247-62-1; DNA(hypoxanthine) glycohydrolase; deoxyribonucleic acid glycosylase; hypoxanthine-DNA glycosylase. Cat No: EXWM-3969. | |
| DNA-dependent protein kinase catalytic subunit (2836-2844) | DNA-dependent protein kinase catalytic subunit (2836-2844) is a peptide derived from DNA-dependent protein kinase catalytic subunit. PRKDC (DNA-PKcs) mutations were found in 3 out of 10 of endometriosis-associated ovarian cancers, as well as in the field defects from which they arose. They were also found in 10% of breast and pancreatic cancers. Synonyms: DNA-PK catalytic subunit (2836-2844); DNA-PKcs (2836-2844). | |
| DNA-directed DNA polymerase | Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA polymerase I; DNA polymerase II; DNA polymerase III; DNA polymerase α; DNA polymerase β; DNA polymerase γ; DNA nucleotidyltransferase (DNA-directed); deoxyribonucleate nucleotidyltransferase; deoxynucleate polymerase; deoxyribonucleic acid. Enzyme Commission Number: EC 2.7.7.7. CAS No. 9012-90-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3281; DNA-directed DNA polymerase; EC 2.7.7.7; 9012-90-2; DNA polymerase I; DNA polymerase II; DNA polymerase III; DNA polymerase α; DNA polymerase β; DNA polymerase γ; DNA nucleotidyltransferase (DNA-directed); deoxyribonucleate nucleotidyltransferase; deoxynucleate polymerase; deoxyribonucleic acid duplicase; deoxyribonucleic acid polymerase; deoxyribonucleic duplicase; deoxyribonucleic polymerase; deoxyribonucleic polymerase I; DNA duplicase; DNA nucleotidyltransferase; DNA polymerase; DNA replicase; DNA-dependent DNA polymerase; duplicase; Klenow fragment; sequenase; Taq DNA polymerase; Taq Pol I; Tca DNA polymerase. Cat No: EXWM-3281. | |
| DNA-directed RNA polymerase | Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to α-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase). Group: Enzymes. Synonyms: RNA polymerase; RNA nucleotidyltransferas. Enzyme Commission Number: EC 2.7.7.6. CAS No. 9014-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3271; DNA-directed RNA polymerase; EC 2.7.7.6; 9014-24-8; RNA polymerase; RNA nucleotidyltransferase (DNA-directed); RNA polymerase I; RNA polymerase II; RNA polymerase III; C RNA formation factors; deoxyribonucleic acid-dependent ribonucleic acid polymerase; DNA-dependent ribonucleate nucleotidyltransferase; DNA-dependent RNA nucleotidyltransferase; DNA-dependent RNA polymerase; ribonucleate nucleotidyltransferase; ribonucleate polymerase; C ribonucleic acid formation factors; ribonucleic acid nucleotidyltransferase; ribonucleic acid polymerase; ribonucleic acid transcriptase; ribonucleic polymerase; ribonucleic transcriptase; RNA nucleotidyltransferase; RNA transcriptase; transcriptase; RNA nucleotidyltransferase I. | |
| DNA Electroporation Buffer (30 ml) | Electroporation buffer optimized for high transfection efficacy of pDNA into primary cultures and hard-to-transfect cell lines. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 4067. |  Nevada, Texas, USA |
| DNA-formamidopyrimidine glycosylase | May play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents. Also involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA. Group: Enzymes. Synonyms: Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein. Enzyme Commission Number: EC 3.2.2.23. CAS No. 78783-53-6. Fpg Protein. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3977; DNA-formamidopyrimidine glycosylase; EC 3.2.2.23; 78783-53-6; Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein. Cat No: EXWM-3977. | |
| DNA helicase | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. Some of them unwind duplex DNA with a 3' to 5' polarity, others show 5' to 3' polarity or unwind DNA in both directions. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.13 (RNA helicase). Group: Enzymes. Synonyms: 3' to 5' DNA helicase; 3'-5' DNA helicase; 3'-5' PfDH; 5' to 3' DNA helicase; AvDH1; BACH1 helicase; BcMCM; BLM protein; BRCA1-associated C-terminal helicase; CeWRN-1; Dbp9p; DmRECQ5; DNA helicase 120; DNA helicase A; DNA helicase E; DNA helicase I. Enzyme Commission Number: EC 3.6.4.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4702; DNA helicase; EC 3.6.4.12; 3' to 5' DNA helicase; 3'-5' DNA helicase; 3'-5' PfDH; 5' to 3' DNA helicase; AvDH1; BACH1 helicase; BcMCM; BLM protein; BRCA1-associated C-terminal helicase; CeWRN-1; Dbp9p; DmRECQ5; DNA helicase 120; DNA helicase A; DNA helicase E; DNA helicase II; DNA helicase III; DNA helicase RECQL5β; DNA helicase VI; dnaB; DnaB helicase E1; helicase HDH IV; Hel E; helicase DnaB; helicase domain of bacteriophage T7 gene 4 protein helicase; PcrA helicase; UvrD; hHcsA; Hmi1p; hPif1; MCM helicase; MCM protein; MER3 helicase; MER3 protein; MPH1; PcrA; PcrA helicase; PDH120; PfDH A; Pfh1p; PIF1. Cat No: EXWM-4702. | |
| DNA ligase 3 isoform alpha precursor (790-806) | DNA ligase 3 isoform alpha precursor (790-806) is a bioactive peptide of DNA ligase 3 isoform alpha precursor. DNA ligases are critical enzymes of DNA metabolism. DNA ligase 3 isoform alpha is involved in repair and recombination. | |
| DNA ligase (ATP) | The enzyme catalyses the ligation of DNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of single-strand breaks in duplex DNA. Catalysis occurs by a three-step mechanism, starting with the activation of the enzyme by ATP, forming a phosphoramide bond between adenylate and a lysine residue. The adenylate group is then transferred to the 5'-phosphate terminus of the substrate, forming the capped structure 5'-(5'-diphosphoadenosine)-[DNA]. Finally, the enzyme catalyses a nucleophilic attack of the 3'-OH terminus on the capped terminus, which results in formation of the phosphodiester bond and release of the adenylate. RNA can also act as substrate, to some extent. cf. EC 6.5.1.2, DNA ligase (NAD+), EC 6.5.1.6, DNA ligase (ATP or NAD+), and EC 6.5.1.7, DNA ligase (ATP, ADP or GTP). Group: Enzymes. Synonyms: polydeoxyribonucleotide synthase (ATP). Enzyme Commission Number: EC 6.5.1.1. CAS No. 9015-85-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5820; DNA ligase (ATP); EC 6.5.1.1; 9015-85-4; polydeoxyribonucleotide synthase (ATP); polynucleotide ligase (ambiguous); sealase; DNA repair enzyme (ambiguous); DNA joinase (ambiguous); DNA ligase (ambiguous); deoxyribonucleic ligase (ambiguous); deoxyribonucleate ligase (ambiguou. | |
| DNA ligase (ATP, ADP or GTP) | The enzymes from the archaea Hyperthermus butylicus and Sulfophobococcus zilligii are active with ATP, ADP or GTP. They show no activity with NAD+. Different from EC 6.5.1.1, DNA ligase (ATP), which is specific for ATP, and EC 6.5.1.6, DNA ligase (ATP or NAD+) which can utilize either ATP or NAD+. Group: Enzymes. Enzyme Commission Number: EC 6.5.1.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5826; DNA ligase (ATP, ADP or GTP); EC 6.5.1.7. Cat No: EXWM-5826. | |
| DNA ligase (ATP or NAD+) | The enzymes from the archaea Thermococcus fumicolans and Thermococcus onnurineus show high activity with either ATP or NAD+, and significantly lower activity with TTP, GTP, and CTP. Different from EC 6.5.1.1, DNA ligase (ATP), EC 6.5.1.2, DNA ligase (NAD+) and EC 6.5.1.7, DNA ligase (ATP, ADP or GTP). Group: Enzymes. Enzyme Commission Number: EC 6.5.1.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5825; DNA ligase (ATP or NAD+); EC 6.5.1.6. Cat No: EXWM-5825. | |
| DNA ligase (NAD+) | Catalyses the formation of a phosphodiester at the site of a single-strand break in duplex DNA. RNA can also act as substrate, to some extent. cf. EC 6.5.1.1, DNA ligase (ATP), EC 6.5.1.6, DNA ligase (ATP or NAD+), and EC 6.5.1.7, DNA ligase (ATP, ADP or GTP). Group: Enzymes. Synonyms: polydeoxyribonucleotide synthase (NAD+); polynucleotide ligase (NAD+); DNA repair enzyme (ambiguous); DNA joinase (ambiguous); polynucleotide synthetase (nicotinamide ad. Enzyme Commission Number: EC 6.5.1.2. CAS No. 37259-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5821; DNA ligase (NAD+); EC 6.5.1.2; 37259-52-2; polydeoxyribonucleotide synthase (NAD+); polynucleotide ligase (NAD+); DNA repair enzyme (ambiguous); DNA joinase (ambiguous); polynucleotide synthetase (nicotinamide adenine dinucleotide); deoxyribonucleic-joining enzyme (ambiguous); deoxyribonucleic ligase (ambiguous); deoxyribonucleic repair enzyme (ambiguous); deoxyribonucleic joinase (ambiguous); DNA ligase (ambiguous); deoxyribonucleate ligase (ambiguous); polynucleotide ligase (ambiguous); deoxyribonucleic acid ligase (ambiguous); polynucleotide synthetase (ambiguous); deoxyribonucleic acid joinase (ambiguous); DNA-joining enzyme (ambiguous); polynucleotide ligase (nicotinamide adenine dinucleotide). Cat No: EXWM-5821. | |
| DNA Ligase T4 Reaction Buffer, 10X | DNA Ligase T4 Reaction Buffer, 10X. Group: Molecular Biology. Grades: Molecular Biology Grade. CAS No. 9015-85-4. Pack Sizes: 1.5ml. US Biological Life Sciences. | Worldwide |
| DNA Ligase, T4, Recombinant, BioAssay Kit, 10mM ATP | DNA Ligase, T4, Recombinant, BioAssay Kit, 10mM ATP. Group: Molecular Biology. Grades: Purified. Pack Sizes: 100ul. US Biological Life Sciences. | Worldwide |
| DNA Ligase, T4, Recombinant, BioAssay Kit, T4 DNA Ligase | DNA Ligase, T4, Recombinant, BioAssay Kit, T4 DNA Ligase. Group: Molecular Biology. Grades: Purified. Pack Sizes: 20KU. US Biological Life Sciences. | Worldwide |
| dNaM | dNaM is a synthetic biology tool used in genetic research for nucleotide modification. It allows for the creation of synthetic sequence-specific DNA-binding proteins for gene regulation and therapy. It has potential applications in treating genetic disorders and diseases like cancer through targeted gene editing. Grade: ≥ 97%. CAS No. 1117893-19-2. Molecular formula: C16H18O7. Mole weight: 274.31. | |
| D-NAME hydrochloride | N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME). D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Synonyms: D-NG-Nitroarginine methyl ester; N(G)-Nitro-D-Arginine methyl ester; D-NAME, NG-Nitro-D-arginine methyl ester hydrochloride. Grade: ≥95%. CAS No. 50912-92-0. Molecular formula: C7H15N5O4·HCl. Mole weight: 269.7. | |
| DNA N6-methyladenine demethylase | Contains iron(II). Catalyses oxidative demethylation of DNA N6-methyladenine, a prevalent modification in LINE-1 transposons, which are specifically enriched on the human X chromosome. Group: Enzymes. Synonyms: ALKBH1. Enzyme Commission Number: EC 1.14.11.51. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0670; DNA N6-methyladenine demethylase; EC 1.14.11.51; ALKBH1. Cat No: EXWM-0670. | |
| DNA nucleotidylexotransferase | Catalyses template-independent extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Nucleoside may be ribo- or 2'-deoxyribo-. Group: Enzymes. Synonyms: terminal deoxyribonucleotidyltransferase; terminal addition enzyme; addase; deoxynucleotidyl terminal transferase; deoxyribonucleic acid nucleotidyltransferase; deoxyribonucleic nucleotidyltransferase; terminal deoxynucleotide transferase; TdT. Enzyme Commission Number: EC 2.7.7.31. CAS No. 9027-67-2. TdT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3242; DNA nucleotidylexotransferase; EC 2.7.7.31; 9027-67-2; terminal deoxyribonucleotidyltransferase; terminal addition enzyme; addase; deoxynucleotidyl terminal transferase; deoxyribonucleic acid nucleotidyltransferase; deoxyribonucleic nucleotidyltransferase; terminal deoxynucleotide transferase; TdT. Cat No: EXWM-3242. | |
| DNA oxidative demethylase | Contains iron; activity is slightly stimulated by ascorbate. Catalyses oxidative demethylation of the DNA base lesions N1-methyladenine, N3-methylcytosine, N1-methylguanine, and N3-methylthymine. It works better on single-stranded DNA (ssDNA) and is capable of repairing damaged bases in RNA. Group: Enzymes. Synonyms: alkylated DNA repair protein; α-ketoglutarate-dependent dioxygenase ABH1; alkB (gene name). Enzyme Commission Number: EC 1.14.11.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0651; DNA oxidative demethylase; EC 1.14.11.33; alkylated DNA repair protein; α-ketoglutarate-dependent dioxygenase ABH1; alkB (gene name). Cat No: EXWM-0651. | |
| DNA-PK Inhibitor IV | DNA-PK inhibitor IV is an inhibitor of DNA-dependent protein kinase (DNA-PK). It also inhibits the phosphatidylinositol 3-kinase (PI3K) isoforms p110β, p110δ, and p110γ but not p110α or class II PI3Ks, PI4Kβ, ATM, ATR, mTOR, CK2, or GRK2. Synonyms: 2-hydroxy-4-(4-morpholinyl)-benzaldehyde. Grade: ≥98%. CAS No. 70362-07-1. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
| DNA-PK Substrate | DNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11-24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.). Uses: Scientific research. Category: Peptides. CAS No. 146064-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5429. | |
| DNA Polymerase Alpha from Human, Recombinant | DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase alpha complex consists of 4 subunits: POLA1, POLA2, PRIM1, and PRIM2. Group: Enzymes. Synonyms: DNA polymerase alpha; DNA polymerase; Pol &alpha. Enzyme Commission Number: EC 2.7.7.7. CAS No. 9012-90-2. DNA Polymerase. Activity: 16,835 units/mg, 5 units/ul. Storage: Store at -80°CNote: Avoid multiple freeze / thaw cycles or frequent temperature changes. Species: Human. DNA polymerase alpha; DNA polymerase; Pol &alpha. Cat No: NATE-1922. | |
| DNA Polymerase for PAGE | DNA Polymerase for PAGE. Dna polymerase for page is purified from e. coliexpressing a cloned dna polymerase from thermus aquaticus. the enzyme consists of a single polypeptide with a molecular weight of approximately 94 kda. dna polymerase for page has 5?-3? dna polymerase activity and 5?-3? exonuclease activity. lt lacks 3?-5? exonuclease activity. this enzyme is supplied with unique buffer, and its pcr product is suitable for sds-page and agarose gel electrophoresis. Group: Cloning Enzymes. Purity: 2500U. Storage: Store at -20 ?. Cat No: CE-3004. | |
| DNA Polymerase I Klenow Fragment, Reaction Buffer (10X) | DNA Polymerase I Klenow Fragment, Reaction Buffer (10X) supplied with D3940. Group: Molecular Biology. Grades: Molecular Biology Grade. CAS No. 9012-90-2. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| DNA Polymerase I Reaction Buffer, 10X | Reaction Buffer (10X) for D3935. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| DNA Polymerase, Pfu, Reaction Buffer, 10X | D3935-65B1(10X Reaction Buffer): Group: Molecular Biology. Grades: Purified. Pack Sizes: 10ml. US Biological Life Sciences. | Worldwide |
| DNA Polymerase T4 Buffer, 5X | Reaction buffer for D3943: DNA Polymerase T4, Exo-Minus. Group: Molecular Biology. Pack Sizes: 350ul. US Biological Life Sciences. | Worldwide |
| DNA relaxation-IN-1 | DNA relaxation-IN-1 (Compound 27) is a DNA ligase 1 DNA Lig1) inhibitor. DNA relaxation-IN-1 inhibits DNA ligation and disrupts the DNA relaxing activity of DNA Lig1. DNA relaxation-IN-1 induces Apoptosis. DNA relaxation-IN-1, in combination with Topotecan (HY-13768), exhibits synergistic antiproliferative effects against colorectal cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2190506-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161152. | |
| DNA repair protein RAD50 (1281-1289) | A fragment of DNA repair protein RAD50. RAD50 is a component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. This peptide can be used in Ovarian carcinoma research. | |
| DNA, Salmon (Deoxyribonucleic acid) | DNA, Salmon (Deoxyribonucleic acid). Group: Biochemicals. Alternative Names: DNA-Na. Grades: Highly Purified. CAS No. 9007-49-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| DNase I, Bovine pancreas | DNase I, Bovine pancreas is a Ca²?/Mg²?-dependent endonuclease that cleaves phosphodiester bonds double-stranded DNA, classified under EC 3.1.21.1 as a hydrolase. It binds to the minor groove of DNA, with key amino acids like R111, Y211, and N170 interacting with the DNA backbone to facilitate catalysis, while residues N74 and S206 in the active site are crucial for substrate binding and DNA recognition. DNase I is essential for DNA degradation, chromatin research, and is widely used to generate smaller DNA fragments for genomic studies and to examine DNA-protein interactions in chromatin remodeling research. Group: Inhibitors. CAS No. 9003-98-9. Pack Sizes: 50mg. Product ID: E7018. |  United States; Europe |
| DNase I, Bovine pancreas | DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1]. Uses: Scientific research. Category: Enzymes. Alternative Names: DNase. CAS No. 9003-98-9. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-108882. | |
| DNase I (filtered) | DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune reactions. Decreased DNase I activity may be associated with the occurrence and development of systemic lupus erythematosus (SLE). DNase I (filtered) is filtered through a 0.22 μM membrane and is not tested for pyrogenicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-98-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108882C. | |
| DNase I RNase & Protease free | DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9003-98-9. Pack Sizes: 2.5 KU; 10 KU. Product ID: HY-108882B. | |
| DNA sodium salt (Fish sperm) | DNA sodium salt (Fish sperm). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
| DNA topoisomerase | These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC 5.99.1.3 DNA topoisomerase (ATP-hydrolysing). Group: Enzymes. Synonyms: type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase. Enzyme Commission Number: EC 5.99.1.2. CAS No. 80449-01-0. TOPO I. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5637; DNA topoisomerase; EC 5.99.1.2; 80449-01-0; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase. Cat No: EXWM-5637. | |
| DNA topoisomerase (ATP-hydrolysing) | The enzyme can introduce negative superhelical turns into double-stranded circular DNA. One unit has nicking-closing activity, and another catalyses super-twisting and hydrolysis of ATP (cf. EC 5.99.1.2 DNA topoisomerase). Group: Enzymes. Synonyms: type II DNA topoisomerase; DNA-gyrase; deoxyribonucleate topoisomerase; deoxyribonucleic topoisomerase; topoisomerase; DNA topoisomerase II. Enzyme Commission Number: EC 5.99.1.3. CAS No. 142805-56-9. TOPO II. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5638; DNA topoisomerase (ATP-hydrolysing); EC 5.99.1.3; 142805-56-9; type II DNA topoisomerase; DNA-gyrase; deoxyribonucleate topoisomerase; deoxyribonucleic topoisomerase; topoisomerase; DNA topoisomerase II. Cat No: EXWM-5638. | |
| DNDI-6148 | DNDI-6148 is a novel preclinical candidate for the research of visceral leishmaniasis. Uses: Scientific research. Category: Signaling pathways. CAS No. 2243909-59-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139854. | |
| DNDI-6174 | DNDI-6174 is an orally active Leishmania cytochrome b (Qi site of cytochrome bc1 complex/complex III) inhibitor. DNDI-6174 binds to the Qi site of Leishmania cytochrome b, inhibits cytochrome bc1 complex activity in the parasite's electron transport chain across promastigote and axenic amastigote stages. DNDI-6174 reduces parasite burden in rodent models, inhibits growth of various Leishmania species, drug-resistant clinical isolates, and Trypanosoma cruzi, with marginal activity against Trypanosoma brucei. DNDI-6174 can be used for the research of visceral leishmaniasis, cutaneous leishmaniasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2868298-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162066. | |
| D-Neopterin | Precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees. Group: Biochemicals. Alternative Names: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; Neopterin; 2-Amino-4-hydroxy-6- (1, 2, 3-trihydroxypropyl) pteridine; 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone; 6-D-erythro-Neopterin; D-(+)-Neopterin; D-erythro-Neopterin. Grades: Highly Purified. CAS No. 2009-64-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C9H11N5O4, Molecular Weight: 253.21. US Biological Life Sciences. | Worldwide |
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