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A potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine kinase (PDGFR β) (IC50 = 80 nM). Displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C. Group: Biochemicals. Alternative Names: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride. Grades: Highly Purified. CAS No. 1123491-15-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C16H14N2O2.2HCl, Molecular Weight: 339.22. US Biological Life Sciences.
DMPQ dihydrochloride is a potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) (IC50 = 80 nM). It displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C. Synonyms: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1123491-15-5. Molecular formula: C16H14N2O2.2HCl. Mole weight: 339.22.
DMQA
DMQA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N'-Dimethyl-quinacridone. Product Category: Organic Light Emitting Diode (OLED). CAS No. 19205-19-7. Molecular formula: C22H16N2O2. Mole weight: 340.37 g/mol. Purity: 95%+. IUPACName: 5,12-dimethylquinolino[2,3-b]acridine-7,14-dione. Canonical SMILES: CN1C2=CC=CC=C2C(=O)C3=CC4=C(C=C31)C(=O)C5=CC=CC=C5N4C. Density: 1.32 g/ml. Product ID: ACM19205197. Alfa Chemistry ISO 9001:2015 Certified. Categories: Dmanisi hominins.
DMRIE
DMRIE is a quaternary ammonium compound with surfactant properties. It features a hydrophilic head with dimethyl and hydroxyethyl groups, and two hydrophobic tetradecyl (C14) alkyl chains, making it effective in forming micelles and emulsifying agents. The bromide counterion balances the charge of the ammonium group. This compound is commonly used in formulations requiring surfactants, such as in detergents, personal care products, and possibly in drug delivery systems due to its amphiphilic nature. Synonyms: N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-1-propaniminium Bromide; 1-Propanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-, bromide (1:1); Dimethyl-2-hydroxyethyl-2,3-ditetradecyloxypropylammonium bromide; Dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium; N-[1-(2,3-Ditetradecyloxy)propyl]-N,N-dimethyl-N-hydroxyethylammonium bromide; N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)propan-1-aminium bromide. Grade: ≥95%. CAS No. 153312-64-2. Molecular formula: C35H74BrNO3. Mole weight: 636.87.
DMSA Coated Fe2O3 Nanoparticles
DMSA Coated Fe2O3 Nanoparticles. Group: Nanopowders. CAS No. 1317-61-9.
DMSA Coated Fe3O4 Nanoparticles
DMSA Coated Fe3O4 Nanoparticles. Uses: Designed for use in research and industrial production. Product Category: Metal Nano-materials. CAS No. 12227-89-3. Product ID: ACM12227893-3. Alfa Chemistry ISO 9001:2015 Certified.
DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 ?M. DMT1 blocker 2 can block iron uptake by enterocytes in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1062648-63-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126302.
DMT-2'-F-Bz-dA
DMT-2'-F-Bz-dA can be used in the synthesis of nucleotides and nucleic acids. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 136834-21-4. Pack Sizes: 250 mg; 1 g. Product ID: HY-W093086.
DMT-2'-F-dC(dmf)-CE-Phosphoramidite
DMT-2'-F-dC(dmf)-CE-Phosphoramidite is a phosphoramidite compound used in the synthesis of modified oligonucleotides. This molecule is derived from deoxycytidine (dC) and features several modifications: a dimethoxytrityl (DMT) group at the 5' position, a fluorine atom at the 2' position, and a dimethylformamidine (dmf) protecting group on the exocyclic amino group of the cytosine base. The phosphoramidite group is attached to the 3' position, enabling its incorporation into synthetic DNA sequences. DMT-2'-F-dC(dmf)-CE-Phosphoramidite is particularly valuable in creating stable and effective oligonucleotides for diagnostic tools, therapeutic agents, and in studying nucleic acid interactions. The fluorine substitution at the 2' position also contributes to improved binding affinity and specificity in hybridization assays, making this compound a versatile tool in molecular biology and medical research. Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxopyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-N4-DMF-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; 2'-F C(DMF) amidite; 2'-Fluoro-C(DMF)-3'-phosphoramidite; N4-DMF-5'-O-DMT-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; N4-Dimethy. Grade: ≥98%. Molecular formula: C42H52FN6O7P. Mole weight: 802.89.
DMT-2'Fluoro-dA(bz) Phosphoramidite
DMT-2'Fluoro-dA(bz) Phosphoramidite is an indispensable phosphoramidite derivative compound, used extensively in the synthesis of biomedical modified oligonucleotides. It emerges as a prominent tool aimed at studying multifarious afflictions, encompassing cancer, hereditary anomalies and insidious viral invasions. Synonyms: 2'-F-Bz-A-CEP. Molecular formula: C46H51FN7O7P. Mole weight: 863.91.
DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite
DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite is a phosphoramidite compound used for the synthesis of locked nucleic acids (LNAs). This molecule is derived from a nucleoside and features several key modifications: a dimethoxytrityl (DMT) group at the 5' position, a 2'-O-4'-C methylene bridge (creating a locked ribose conformation), and a cyanoethyl (CE) phosphoramidite group for incorporation into oligonucleotides. DMT-2'-O-4'-C Locked-Tr-CE Phosphoramidite is valuable in various applications, including antisense therapy, siRNA, miRNA research, and diagnostic assays. The enhanced stability and binding properties of LNA-modified oligonucleotides make them powerful tools in molecular biology and medical research, providing greater specificity and efficacy in targeting RNA or DNA sequences. Synonyms: DMTr-LNA-5MeU-3-CED-phosphoramidite; 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-thymidine-3'-cyanoethyl Phosphoramidite; 1-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'-O-(4,4'-Dimethoxytrityl)-LNA-thymidine-3'-cyanoethyl phosphoramidite; DMT-locT Amidite; LNA-T phosphoramidite. Grade: ≥98% by HPLC. CAS No. 206055-75-6. Molecular formula: C41H49N4O9P. Mole weight: 772.84.
DMT-2'-O-Methyl-rC(tac) (R)-Phosphoramidite
DMT-2'-O-Methyl-rC(tac) (R)-Phosphoramidite, a highly esteemed resource within the biomedical industry, plays a pivotal role in the synthesis of modified nucleic acids. Its profound utility lies in facilitating the integration of a 2'O-methyl cluster onto ribonucleosides, thereby empowering the creation of therapeutic oligonucleotides. Synonyms: 5'-O-DMT-N4-[(4-i-propylphenoxy)acetyl]-2'-O-methylcytidine 3'-CE (R)-phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-N-[[4-(tert-butyl)phenoxy]acetyl]-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)-(R)-phosphoramidite; Dmt-2'-O-me-rc(tac) (R)-amidite; 2'-O-Methyl-rC(N-tac)-(R)-Phosphoramidite; 2'-OMe-rC(TAc) CE (R)-phosphoramidite; DMT-2'O-Methyl-rC(tac) (R)-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (R)-. Grade: ≥97% by HPLC. CAS No. 179486-26-1. Molecular formula: C52H64N5O10P. Mole weight: 950.07.
DMT-2?O-TBDMS-rA(ac)-1-15N phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rA(ac)-8-13C phosphoramidite
?98 atom % 13C, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rC(ac)-1,3-15N2 phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rC(ac)-3-15N phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rC(ac)-6-13C,5-d phosphoramidite
?98 atom % 13C, ?98 atom % D, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rG(ac)-1-15N phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rG(ac)-8-13C phosphoramidite
?98 atom % 13C, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rU-1,3-15N2 phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rU-3-15N phosphoramidite
?98 atom % 15N, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-2?O-TBDMS-rU-6-13C,5-d phosphoramidite
?98 atom % D, ?98 atom % 13C, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
DMT-Biotin
DMT-Biotin. CAS No. 144095-63-6. Molecular formula: C31H34N2O5S. Mole weight: 546.68.
DMT-Biotin-TEG
DMT-Biotin-TEG. CAS No. 1093231-05-0. Molecular formula: C37H47N3O7S. Mole weight: 677.85.
DMT-C3(Biotin)-CPG is used to attach biotin with a C3 spacer to the 3' end of an oligonucleotide.
DMT-(C-Et)-LNA-T
DMT-(C-Et)-LNA-T is a modified thymidine nucleoside used in oligonucleotide synthesis. The 5'-hydroxyl group is protected with a dimethoxytrityl (DMTr) group to facilitate its use in solid-phase synthesis. This modification helps improve the stability and functionality of the resulting oligonucleotides, making it suitable for use in DNA-based therapeutic and research applications, particularly where enhanced stability and reduced degradation are desired. Synonyms: 1-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-6-deoxy-α-L-mannofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2,5-Anhydro-4-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-6-deoxy-alpha-L-mannofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-cEt-BNA-Thymidine; 5'-ODMT cEt T. Grade: ≥95%. CAS No. 1197033-21-8. Molecular formula: C33H34N2O8. Mole weight: 586.64.
DMT-Cl
Used in the coupling stage of nucleoside (hydroxyl protecting agent). Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 4,4?-Dimethoxytrityl chloride. CAS No. 40615-36-9.
Luxembourg Bio Technologies
DMT-C(N-bz) 2'OMe
DMT-C(N-bz) 2'OMe. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
DMTDAc
DMTDAc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,7-Bis(9,9-dimethylacridin-10(9H)-yl)-9,9-dimethyl-9H-thioxanthene-10,10-dioxide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1877288-52-2. Molecular formula: C45H40N2O2S. Mole weight: 672.88 g/mol. Product ID: ACM1877288522. Alfa Chemistry ISO 9001:2015 Certified.
DMT-dG(Ac)-5'-CE Reverse Phosphoramidite
DMT-dG(Ac)-5'-CE Reverse Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-acetyl protecting group at the 5'-end of DNA strands. This reagent features a reverse configuration where the DMT group is attached to the 3'-OH and the phosphoramidite to the 5'-OH, allowing synthesis in the 5' to 3' direction. It is particularly useful for synthesizing oligonucleotides with hairpin loops containing parallel strands or nuclease-resistant linkages. Synonyms: idG(N-Ac) Phosphoramidite; idG(N-Ac) CE Phosphoramidite; 3'-DMTr-dG(Ac)-CE Reverse; N2-Acetyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(Ac)-CE Inverted Phosphoramidite; N2-Ac-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(Ac)-5'-CE-Phosphoramidite; Rev dG(Ac). Grade: ≥97%. Molecular formula: C42H50N7O8P. Mole weight: 811.88.
DMT-dG(DMF)-5'-CE Reverse Phosphoramidite
DMT-dG(DMF)-5'-CE Reverse Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-dimethylformamidine (DMF) protecting group at the 5'-end of DNA strands. This reagent features a reverse configuration where the DMT group is attached to the 3'-OH and the phosphoramidite to the 5'-OH, allowing synthesis in the 5' to 3' direction. It is particularly useful for synthesizing oligonucleotides with hairpin loops containing parallel strands or nuclease-resistant linkages. Synonyms: idG(N-dmf) Phosphoramidite; idG(N-dmf) CE Phosphoramidite; 3'-DMTr-dG(DMF)-CE Reverse; N2-Dimethylformamidine-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(DMF)-CE Inverted Phosphoramidite; N2-DMF-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(DMF)-5'-CE-Phosphoramidite; Rev dG(DMF); Guanosine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥97%. CAS No. 261728-23-8. Molecular formula: C43H53N8O7P. Mole weight: 824.91.
DMT-dG(dmf)-CE Reverse Phosphoramidite
DMT-dG(dmf)-CE Reverse Phosphoramidite. Alternative Names: 3'-DMTr-dG(dmf). MFCD30475583. HY-147320. CS-0565766. CAS No. 261728-23-8. Product ID: PIPB-0333. Molecular formula: C43H53N8O7P.
DMT-dG(iBu)-5'-CE Reverse Phosphoramidite
DMT-dG(iBu)-5'-CE Reverse Phosphoramidite is a compound used in the synthesis of oligonucleotides, specifically designed for automated DNA synthesis systems. It is essential for the efficient and precise assembly of custom DNA sequences in laboratory settings, ensuring that each nucleotide is added correctly and in the desired sequence during automated oligonucleotide synthesis processes. Synonyms: 3'-DMTr-dG(iBu)-CE Reverse; N2-Isobutyryl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-5'-cyanoethyl phosphoramidite; DMT-dG(iBu)-CE Inverted Phosphoramidite; Guanosine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 5-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N2-iBu-3'-O-DMTr-2'-deoxyguanosine 5'-O-CE-phosphoramidite; 3'-O-DMTr-dG(iBu)-5'-CE-Phosphoramidite; Rev dG(iBu). Grade: ≥95%. CAS No. 140839-24-3. Molecular formula: C44H54N7O8P. Mole weight: 839.92.
DMT-dZ-CE Phosphoramidite
DMT-dZ-CE Phosphoramidite is a critical reagent in the automated synthesis of oligonucleotides, providing necessary protection to various functional groups to ensure accurate and efficient assembly of custom DNA or RNA sequences. The use of such modified nucleotides allows for the incorporation of unique properties and functionalities into the synthesized oligonucleotides, which can be tailored for specific research and biotechnological applications. Synonyms: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-α-[[phenylmethyl]amino]-α-oxo-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[[(phenylmethyl)amino]carbonyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. Molecular formula: C47H54N5O9P. Mole weight: 863.95.
DMTMM
DMTMM (4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. CAS No. 3945-69-5. Pack Sizes: 25 g; 100 g. Product ID: HY-Y1168.
DMTr-dH2U-amidite
DMTr-dH2U-amidite is an invaluable entity, emerging prominently due to its indispensability in the synthesis of nucleotide analogs and customized oligonucleotides. It assumes a pivotal function in the advancement of pharmaceuticals designed to study an array of ailments, ranging from cancer to viral infections and genetic anomalies. Synonyms: 2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine-3'-CED phosphoramidite; 4(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-. Grade: ≥95%. CAS No. 151503-28-5. Molecular formula: C39H47N4O7P. Mole weight: 714.79.
DMTr-FNA-C(Bz)phosphoramidite
DMTr-FNA-C(Bz)phosphoramidite is an essential compound assuming the role of a phosphoramidite foundational component, expediting the fabrication of nucleic acid analogs. Through its distinctive configuration, it is harnessed in the fabrication of modified oligonucleotides, specifically tailored for investigative applications, notably in the precise targeting of disease-correlated DNA or RNA sequences encompassing afflictions like cancer and viral infections. Synonyms: FNA C(Bz) amidite; N4-Benzoyl-1-[[2-O-(4,4'-dimethoxytrityloxy)-1-(hydroxymethyl)ethoxy]methyl]cytosine CED phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]methoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; 2-((4-Benzamido-2-oxopyrimidin-1(2H)-yl)methoxy)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. CAS No. 326802-62-4. Molecular formula: C45H52N5O8P. Mole weight: 821.90.
DMTr-LNA-C(Bz)-3-CED-phosphoramidite
DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog which has broad antitumor activity targeting indolent lymphoid malignancies. Synonyms: LNA-C(Bz)-CE Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-LNA-cytidine-3'-cyanoethyl phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O,4'-C-methylene-cytidine 3'-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphorramidite; 5'-O-DMTr-2'-O-4'-C-Locked-C(Bz) Phosphoramidite; DMT-locC(bz)Amidite; DMT-locC(bz) phosphoramidite; LNA-C(Bz)-3-CED-phosphoramidite; Bz-C-LA-CE Phosphoramidite. CAS No. 206055-78-9. Molecular formula: C47H52N5O9P. Mole weight: 861.93.
DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
DMTr-LNA-G(iBu)-3'-CED-phosphoramidite is a phosphoramidite used in the biomedical industry for the synthesis of modified nucleic acids. It contains DMTr-protected LNA-G(iBu)-3'-CED, which enables efficient and stable incorporation of modified bases during DNA/RNA synthesis. Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-LNA-guanosine-3'-cyanoethyl phosphoramidite; LNA-G(ibu) phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; LNA-G(iBu)-CE Phosphoramidite; DMTr-2'-O-4'-C-Locked-rG(iBu)-3'-CE-Phosphoramidite; DMT-2'-O-4'-C-Locked-G(iBu)-CE; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-Guanosine-3'-cyanoethyl Phosphoramidite; N2-iBu-2'-O-4'-C-Locked-Gr-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 206055-77-8. Molecular formula: C45H54N7O9P. Mole weight: 867.94.
DMTr-TNA-U amidite
DMTr-TNA-U amidite is a phosphoramidite monomer used in the RNA synthesis. Synonyms: TNA-U CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-4-[bis(4-methoxyphenyl)phenylmethoxy]-2-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)tetrahydro-3-furanyl 2-cyanoethyl ester; (2R,3R,4S)-4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DMTr-TNA-U-Phosphoramidite. CAS No. 325683-95-2. Molecular formula: C38H45N4O8P. Mole weight: 716.76.
DMU-2105
DMU-2105 is a potent and selective CYP1B1 inhibitor with IC50 of 10 nM and 742 nM for CYP1B1 and CYP1A1, respectively. Synonyms: DMU 2105; DMU2105. Grade: 98%. CAS No. 1031063-36-1. Molecular formula: C18H13NO. Mole weight: 259.3.
DMU-212
DMU-212, an orally active methylated derivative of Resveratrol, has antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. It induces mitotic arrest by inducing apoptosis and activating ERK1/2 protein. Synonyms: 3,4,5,4'-Tetramethoxystilbene; (E)-3,4,5,4'-Tetramethoxystilbene; 1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; trans-3,4,5,4'-tetramethoxystilbene; NSC631365; 3,4,4',5-Tetramethoxy-trans-stilbene; 1,2,3-Trimethoxy-5-[(E)-2-(4-methoxyphenyl)vinyl]benzene; (E)-1,2,3-trimethoxy-5-(4-methoxystyryl)benzene. Grade: 95%. CAS No. 134029-62-2. Molecular formula: C18H20O4. Mole weight: 300.35.
DMU2139
DMU2139 is a potent and specific CYP1B1 inhibitor with IC50 of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively. Grade: 98%. CAS No. 1821143-80-9. Molecular formula: C19H15NO2. Mole weight: 289.3.
DMU2139
DMU2139 is a potent and specific CYP1B1 inhibitor, with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively. DMU2139 showed a very high level of selectivity towards CYP1B1 with respect to the IC50 values obtained with CYP1A1, CYP1A2, CYP3A4, CYP2D6, CYP2C9 and CYP2C19 Sacchrosomes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DMU2139; DMU-2139; DMU 2139. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1821143-80-9. Molecular formula: C19H15NO2. Mole weight: 289.33. Purity: >98%. IUPACName: (E)-1-(6-methoxynaphthalen-2-yl)-3-(pyridin-3-yl)prop-2-en-1-one. Canonical SMILES: O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3. Product ID: ACM1821143809. Alfa Chemistry ISO 9001:2015 Certified.
D-muco-Inositol
D-muco-Inositol is a remarkable biomedical product, used in studying diverse ailments encompassing diabetes, metabolic disorders and oxidative stress. Uses: A growth factor in many plants and animals; used as a nutritional supplement; an isomer of glucose that has traditionally been considered to be a b vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. Synonyms: inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; meso-Inositol; Neo-inositol; D-chiro-Inositol; 1L-Chiro-inositol; D-(+)-chiro-Inositol; cis-Inositol. CAS No. 41546-34-3. Molecular formula: C6H12O6. Mole weight: 180.16.
DMX-5084
DMX-5804 is a potent, selective and orally active inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 suppresses cell death in mouse myocardial infarction (MI), human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), and 3D human engineered heart tissue. Synonyms: BCP30841. CAS No. 2306178-56-1. Molecular formula: C21H19N3O3. Mole weight: 361.39.
DMXAA
DMXAA is a STING agonist that induces antitumor immunological responses. Uses: Antineoplastic agents. Synonyms: 9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo-; 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid; 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid; 5,6-Dimethyl-9-oxo-9H-xanthen-4-ylacetic acid; 5,6-Dimethylxanthenone-4-acetic acid; ASA404; ASA 404; ASA404; AS1404; AS 1404; AS1404; D5817; NSC 640488; Vadimezan. Grade: ≥95%. CAS No. 117570-53-3. Molecular formula: C17H14O4. Mole weight: 282.29.
D-myo-Inositol-1,2,3,4,6-pentaphosphate, sodium salt
D-myo-Inositol-1,2,3,4,6-pentaphosphate, sodium salt is one of many inositol phosphate isomers that act as small soluble second messengers in the transmission of cellular signals. It inhibits phosphorylation and kinase activity of Akt/PKB and induces apoptosis in ovarian, lung, and breast cancer cells. Synonyms: D-myo-inositol-1,2,3,4,6-penta(hydrogen phosphate), pentasodium salt; myo-Inositol, 1,2,3,4,6-pentakis(dihydrogen phosphate), sodium salt (1:5). CAS No. 1872222-99-5. Molecular formula: C6H12O21P5.5Na. Mole weight: 689.96.
D-myo-Inositol-1,2,3,4-tetraphosphate sodium salt
D-myo-Inositol-1,2,3,4-tetraphosphate (Ins(1,2,3,4)-P4) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. Ins(1,2,3,4)-P4 exhibits agonist activity at the Ins(1,4,5)-P3 receptor expressed in CHO cells where it induces Ca2+ mobilization, making it nearly 180-fold less effective than Ins(1,4,5)-P3 in the same assay. Grade: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588.
D-myo-Inositol-1,2,3,5,6-pentaphosphate, sodium salt
D-myo-Inositol-1,2,3,5,6-pentaphosphate, sodium salt is one of many inositol phosphate isomers that act as small soluble second messengers in the transmission of cellular signals. It inhibits phosphorylation and kinase activity of Akt/PKB and induces apoptosis in ovarian, lung, and breast cancer cells. Synonyms: D-myo-inositol-1,2,3,5,6-penta(hydrogen phosphate), pentasodium salt. Molecular formula: C6H12O21P5.5Na. Mole weight: 689.96.
D-myo-Inositol-1,2,3,6-tetraphosphate sodium salt
D-myo-Inositol-1,2,5,6-tetraphosphate sodium salt is an invaluable component, exhibiting tremendous potential in research of an array of afflictions such as cancer, diabetes and neurodegenerative disorders. Its role as a pivotal signaling entity manifests in its remarkable influence on cellular mechanisms encompassing growth, metabolism and inflammation. Grade: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588.
D-myo-Inositol 1,2,3-triphosphate
D-myo-Inositol 1,2,3-triphosphate is an indispensable biomolecular entity, exhibiting its significance as a paramount signaling molecule. Its essentiality derives from its pivotal participation in the intricate process of intracellular calcium release, thereby facilitating various physiological phenomena encompassing neurotransmission and muscular contraction. Synonyms: Ins(1,2,3)P3. CAS No. 41613-02-9. Molecular formula: C6H15O15P3. Mole weight: 420.10.
d-myo-Inositol 1,2,3-trisphosphate tripotassium salt
d-myo-Inositol 1,2,3-trisphosphate tripotassium salt
Sarchem Laboratories New Jersey NJ
D-myo-Inositol-1,2,4,5,6-pentaphosphate, sodium salt
D-myo-Inositol-1,2,4,5,6-pentaphosphate, sodium salt is one of many inositol phosphate isomers that act as small soluble second messengers in the transmission of cellular signals. It inhibits phosphorylation and kinase activity of Akt/PKB and induces apoptosis in ovarian, lung, and breast cancer cells. Synonyms: D-myo-inositol-1,2,4,5,6-penta(hydrogen phosphate), pentasodium salt; Pentasodium (1R,2R,3R,4S,5R,6R)-6-hydroxy-1,2,3,4,5-cyclohexanepentayl pentakis[hydrogen (phosphate)]; 1,2,3,4,5,6-Cyclohexanehexol, 1,2,3,4,5-pentakis(dihydrogen phosphate), sodium salt, (1α,2α,3β,4α,5β,6α)- (1:5). Molecular formula: C6H12O21P5.5Na. Mole weight: 689.96.
D-myo-Inositol-1,2,4,5-tetraphosphate sodium salt
Ins(1,2,4,5)P4 is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals. Grade: ≥98%. Molecular formula: C6H12O18P4·4Na. Mole weight: 588.
D-myo-Inositol-1,2,6-triphosphate sodium salt
D-myo-Inositol-1,2,6-triphosphate sodium salt is an eminent compound assuming the significant function of a secondary messenger molecule, concentrating solely on cellular signal transduction pathways. Exercising crucial control over intracellular calcium levels, this compound ultimately governs a myriad of cellular processes. Synonyms: 1,2,6-IP3. Molecular formula: C6H12O15P3.xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt
Inositol-1,3,4,5,6-pentaphosphateis one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a 3-kinase/3-phosphatase cycle. Grade: >98%. Molecular formula: C6H7O21P5·10NH4. Mole weight: 750.36.
D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium salt
The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It exhibits antiangiogenic activity in vitro, blocking capillary tube formation of HUVEC, as well as antitumor effects against cancer xenografts in nude mice. Grade: ≥98%. Molecular formula: C6H12O21P5·5Na. Mole weight: 689.96.
D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt. Group: Biochemicals. Grades: Purified. CAS No. 145843-69-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt is the octapotassium salt of D-myo-Inositol-1,3,4,5-tetrakisphosphate, which is the phosphorylation product of inositol 1,4,5-trisphosphate and the enantiomer of the naturally-occurring D-myo-inositol 1,3,4,5-tetrakisphosphate. It is a potent inhibitor of Ins (1,4,5)P3 5-phosphatase with IC50 value of ~150 nM. It facilitates Ca2+ influx by sensitizing Ins (1,4,5)P3-mediated activation of ICRAC. It is a useful intermediate. Synonyms: L-myo-Inositol 1,3,4,5-(tetrakis)phosphate potassium salt. Grade: ≥98% by HPLC. CAS No. 145843-69-2. Molecular formula: C6H8O18P4K8. Mole weight: 804.73.
D-Myo-inositol-1,3,4,5-tetraphosphate ammonium salt
D-Myo-inositol-1,3,4,5-tetraphosphate ammonium salt is a potent bioactive compound with profound impact on intracellular calcium homeostasis, thereby rendering it a promising candidate for studying maladies encompassing neurodegeneration, cardiovascular afflictions and oncogenic processes. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(dihydrogen phosphate), Ammonium Salt; rac-(1R,2R,3S,4R,5R,6R)-4,6-Dihydroxycyclohexane-1,2,3,5-tetrayl tetrakis(dihydrogen phosphate), ammonia Salt; (1R,2S,3S,4S,5S,6S)-4,6-Dihydroxy-1,2,3,5-cyclohexanetetrayl tetrakis[dihydrogen (phosphate)] ammoniate. Grade: >99%. CAS No. 1246355-68-9. Molecular formula: C6H19NO18P4. Mole weight: 517.11.
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt is formed by the phosphorylation of Ins(1,4,5)P4 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)P4 acts in conjunction with IP3 to mobilize intracellular calcium. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(phosphate) octasodium salt; Ins(1,3,4,5)P4 sodium salt. CAS No. 210488-61-2. Molecular formula: C6H8Na8O18P4. Mole weight: 675.93.
D-Myo-inositol 1,3,4-triphosphate hexapotassium salt
D-Myo-inositol 1,3,4-triphosphate hexapotassium salt is a pivotal signaling molecule orchestratingand modulating an array of cellular functions, ranging from neurotransmitter liberation to the orchestration of muscular contracts and extends its impact even towards the delicate domain of immune responses. CAS No. 140385-74-6. Molecular formula: C6H9K6O15P3. Mole weight: 648.64.
D-myo-Inositol-1,3,4-triphosphate sodium salt
D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. Synonyms: D-myo-Inositol-1,3,5-triphosphate, sodium salt; 1,3,4-IP3 (sodium salt); 1,3,5-IP3 (sodium salt); HMS3650K09; Ins(1,3,5)P3 (sodium salt); Ins(1,3,4)-P3 (sodium salt); PD020265; D-myo-Inositol-1,3,4-triphosphate sodium salt. Grade: ≥98%. Molecular formula: C6H12Na3O15P3. Mole weight: 486.04.
D-Myo-inositol-1,3,5-triphosphate ammonium salt
D-Myo-inositol-1,3,5-triphosphate ammonium salt is a prominent compound, possessing immense significance as a pivotal cellular messenger in signal transduction pathways. This product finds substantial utility in the realm of studying calcium signaling, cellular metabolism and the regulation of cellular functions. Synonyms: myo-Inositol-1,3,5-tris(dihydrogen phosphate), Ammonium Salt (1:3); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxycyclohexane-1,3,5-triyl tris(dihydrogen phosphate), Triammonia Salt; IP3(1,3,5); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxy-1,3,5-cyclohexanetriyl tris[dihydrogen (phosphate)] triammoniate; 1,2,3,4,5,6-Cyclohexanehexol, 1,3,5-tris(dihydrogen phosphate), triammonium salt, (1α,2α,3α,4β,5α,6β)-. Grade: >99%. CAS No. 1246355-67-8. Molecular formula: C6H18NO15P3. Mole weight: 437.13.