A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
DyLight DY647 CEP is a fluorescent dye used for oligonucleotide labeling. Grade: ≥85%. Molecular formula: C47H63N4O5PS. Mole weight: 827.07.
DyLight DY677 CEP
DyLight DY677 CEP is a fluorescent dye used for oligonucleotide labeling. Grade: ≥85%. Molecular formula: C55H67N4O5PS. Mole weight: 927.18.
DYn-2
DYn-2 (Anti-dynamin II) is a chemoselective sulfenylated protein probe. DYn-2 binds to sulfenylated proteins with chemoselectivity, enabling the detection of such proteins. DYn-2 can detect differences in intracellular sulfenylation rates. DYn-2 can be used in human cancer research, including studies on breast cancer and lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-dynamin II. CAS No. 1354630-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-116424.
dynamin GTPase
An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4716; dynamin GTPase; EC 3.6.5.5. Cat No: EXWM-4716.
Dynamin inhibitory peptide
Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 251634-21-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1083.
Dynamin inhibitory peptide
Has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Synonyms: Dynamin inhibitory peptide; 251634-21-6; L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-; QVPSRPNRAP; HY-P1083; AKOS024456770; MS-31983; CS-0027626. Grade: >98%. CAS No. 251634-21-6. Molecular formula: C47H80N18O14. Mole weight: 1121.26.
Dynamin inhibitory peptide Acetate
Dynamin inhibitory peptide Acetate has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Molecular formula: C49H84N18O16. Mole weight: 1181.30.
Dynamin inhibitory peptide, myristoylated
An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Synonyms: AKOS024456771; Dynamin inhibitory peptide,myristoylated; PD079118; S-251634-22-7. Grade: >99%. CAS No. 251634-22-7. Molecular formula: C61H107N19O14. Mole weight: 1330.64.
Dynamin inhibitory peptide, myristoylated acetate
An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Molecular formula: C63H111N19O16. Mole weight: 1390.67.
Dynapyrazole-A
Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226517-75-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131873.
Dynarrestin
Dynarrestin is a potent and selective reversible inhibitor of dynein 1 and 2. Dynarrestin exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Synonyms: Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate; 4-(4-Diethylaminophenyl)-2-(2,4-difluoro-phenylamino)-thiazole-5-carboxylic acid ethyl ester. Grade: ≥98% by HPLC. CAS No. 2222768-84-3. Molecular formula: C22H23F2N3O2S. Mole weight: 431.5.
Dynarrestin
Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222768-84-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-121802.
Dynascone®
Dynascone®. CAS No. 56973-85-4. Kosher: Y. VIGON Item # 502771. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, galbascone.
America & Internationally
Dynascone® 10% DPG
Dynascone® 10% DPG. CAS No. MIXTURE. Kosher: Y. VIGON Item # 502772. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Dynasore
Dynasore is a cell-permeable and noncompetitive inhibitor of the GTPase activity of dynamin with IC50 value of 15 μM. Synonyms: Dynamin Inhibitor I; 3-hydroxy-2-[(3,4-dihydroxyphenyl)methylene]hydrazide-2-naphthalenecarboxylic acid; N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide. Grade: 98%. CAS No. 304448-55-3. Molecular formula: C18H14N2O4. Mole weight: 322.31.
Dynasore
Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV). Group: Inhibitors. CAS No. 304448-55-3. Pack Sizes: 10mg. Product ID: S8047. Formula: C18H14N2O4. Smiles: C1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3)O)O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Dynasore
Dynamin GTPase inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Group: Biochemicals. Grades: Highly Purified. CAS No. 304448-55-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H14N2O4. 0.5H2O. US Biological Life Sciences.
Worldwide
Dynasore
Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration. Uses: Scientific research. Category: Signaling pathways. CAS No. 304448-55-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15304.
dynein ATPase
A multisubunit protein complex associated with microtubules. Hydrolysis of ATP provides energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome towards the microtubule's minus end. It also functions in the movement of eukaryotic flagella and cilia. It consists of two heavy chains (about 500 kDa), three-four intermediate chains (about 70 kDa) and four light chains (about 50 kDa). Group: Enzymes. Synonyms: dynein adenosine 5'-triphosphatase. Enzyme Commission Number: EC 3.6.4.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4704; dynein ATPase; EC 3.6.4.2; dynein adenosine 5'-triphosphatase. Cat No: EXWM-4704.
Dynemicin A
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grade: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47.
Dynemicin L
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylic acid, 8-chloro-5,8,9,14,15,16-hexahydro-1,4,6,17-tetrahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9R,14S,17S,18S)-(9CI). CAS No. 127032-74-0. Molecular formula: C30H22NO9Cl. Mole weight: 575.95.
Dynemicin M
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grade: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49.
Dynemicin N
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylicacid,5,8,9,14,15,16-hexahydro-1,4,6,8,17-pentahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9S,14S,17S,18S)-(9CI). CAS No. 127003-55-8. Molecular formula: C30H23NO10. Mole weight: 557.50.
Dynemicin O
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49.
Dynemicin P
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47.
Dynemicin Q
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: 9,8,14-(2)Buten(1)yl(4)ylideneanthra(1,2-b)benz(f)azocine-5,6,20-trione,8,9,14,15-tetrahydro-1,4,6,8,17,19-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*))-. CAS No. 138370-14-6. Molecular formula: C28H19NO9. Mole weight: 513.45.
Dyngo-4a
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1?μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively. Synonyms: Hydroxy-Dynasore; 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide; 3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide; Dyngo 49. Grade: ≥96%. CAS No. 1256493-34-1. Molecular formula: C18H14N2O5. Mole weight: 338.31.
Dyngo-4a (Hydroxy-Dynasore)
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1?μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively. Group: Inhibitors. Alternative Names: Hydroxy-Dynasore. CAS No. 1256493-34-1. Pack Sizes: 10mg. Product ID: S7163. Formula: C18H14N2O5. Smiles: C1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3O)O)O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Dynole 2?24
Dynole 2-24 is an active in-cell inhibitor of clathrin-mediated endocytosis (CME) and an indole-based dynamin GTPase inhibitor with an IC50 of 0.56 μM for dynamin I. It is non-toxic and shows enhanced potency against Dynamin I and II in vitro and in cells (IC50(CME) = 1.9 μM), and also shows 4.4-fold selectivity for dynamin I. Synonyms: 1H-Indole-3-methanamine, N-decyl-1-[3-(dimethylamino)propyl]-; N-({1-[3-(Dimethylamino)propyl]-1H-indol-3-yl}methyl)-1-decanamine. CAS No. 1416313-72-8. Molecular formula: C24H41N3. Mole weight: 371.60.
Dynole 2?24
Dynole 2-24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2-24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC50(CME)=1.9 μM). Dynole 2-24 also shows 4.4-fold selectivity for dynamin I. Dynole 2-24 is active in-cell inhibitor of clathrin-mediated endocytosis[1]. CME: Clathrin mediated endocytosis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416313-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145080.
Dynole 34-2
Dynole 34-2 is a dynamin I inhibitor with IC50 value of 1.3 μM. It also inhibits receptor-mediated endocytosis (RME) with IC50 value of 5.0 μM. Synonyms: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide. Grade: ≥99% by HPLC. CAS No. 1128165-88-7. Molecular formula: C25H36N4O. Mole weight: 408.58.
Dynole 34-2
Dynole 34-2. Group: Biochemicals. Grades: Purified. CAS No. 1128165-88-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Dynole 34-2
Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 μM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1128165-88-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107545.
Dynorphin (1-17)
Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Synonyms: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grade: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51.
Dynorphin A
Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 80448-90-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1333.
Dynorphin A 1-10
Dynorphin A 1-10 is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with IC50 of 42.0 μM. Synonyms: Dynorphin A, porcine, fragment 1-10; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline; Dynorphin A (1-10), porcine. Grade: ≥95%. CAS No. 79994-24-4. Molecular formula: C57H91N19O12. Mole weight: 1234.45.
Dynorphin A 1-10 acetate
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Synonyms: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grade: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53.
Dynorphin A (1-10) TFA
Dynorphin A (1-10) TFA is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. Synonyms: Dynorphin A (1-10) Trifluoroacetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.TFA; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline Trifluoroacetate; Dynorphin A (1-10), porcine Trifluoroacetate. Grade: >98%. Molecular formula: C57H91N19O12.C2HF3O2. Mole weight: 1348.48.
Dynorphin A (1-13)
Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grade: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95.
Dynorphin A (1-13) amide
Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Synonyms: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grade: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97.
Dynorphin A (1-17) (Kappa Opioid Receptor Agonist)
An endogenous agonist for kappa opioid receptors. Involved in several neurological disorders, including neuropathic pain, stress, depression, and Alzheimer's and Parkinson's diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 80448-90-4. Pack Sizes: 500ug, 1mg, 5mg, 10mg. Molecular Formula: C99H155N31O23, Molecular Weight: 2147.5. US Biological Life Sciences.
Worldwide
Dynorphin A (1-8)
Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Synonyms: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grade: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15.
Dynorphin A (2-12), porcine
Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu. Molecular formula: C60H105N21O12. Mole weight: 1312.69.
Dynorphin A acetate
Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58.
Dynorphin B (1-13)
Dynorphin B (1-13) acts as an agonist on opioid κ-receptor. Uses: Scientific research. Category: Signaling pathways. CAS No. 83335-41-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1337.
Dynorphin B 1-13
Dynorphin B is a 13-residue opioid peptide, which is derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an opioid peptide and a κ-opioid receptor agonists. It has been implicated in antinociceptive functions. It has also been used to prime cardiogenesis in pluripotent embryonic stem cells. Synonyms: Prodynorphin (226-238) (human); Prodynorphin (228-240) (porcine); Rimorphin; Dynorphin B 1-13; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonine. Grade: ≥95%. CAS No. 83335-41-5. Molecular formula: C74H115N21O17. Mole weight: 1570.84.
Dynorphin B (1-13) acetate
Dynorphin B (1-13) acetate acts as an opioid peptide and a κ-opioid receptor agonists. Molecular formula: C76H119N21O19. Mole weight: 1630.89.
Dynorphin B (1-9) trifluoroacetate salt
Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. Dynorphin B (1-9) is a competitive inhibitor of dynorphin A (1-9). Grade: ≥95%. Molecular formula: C54H78N16O12·xCF3COOH. Mole weight: 1143.30.
Dyphylline
Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor. Uses: Bronchodilator agents; phosphodiesterase inhibitors; vasodilator agents. Synonyms: Diprophylline. Grade: >98%. CAS No. 479-18-5. Molecular formula: C10H14N4O4. Mole weight: 254.24.
Dyphylline
Bronchodilator. Group: Biochemicals. Alternative Names: 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-purine-2,6-dione; Diprophylline. Grades: Highly Purified. CAS No. 479-18-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity (IC50 = 119 nM) and the aggregation of tau and α-syn oligomers. Synonyms: Dyrk1A-IN-1; CS-0255852. Molecular formula: C23H20N4O3S. Mole weight: 432.49.
Dyrk1A-IN-3
Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM). Dyrk1A-IN-3 can be used for the research of neurodegenerative disorders such as Alzheimers Disease, Huntingtons Disease, and Parkinsons Disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493976-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147060.
Dyrk1A-IN-4
Dyrk1A-IN-4 is a potent and orally active Dyrk1A inhibitor. Dyrk1A-IN-4 exhibits IC50s against DYRK1A and DYRK2 of 2 nM and 6 nM. Dyrk1A-IN-4 exhibits the inhibition of the DYRK1A pSer520 autophosphorylation in U2OS cells with an IC50 of 28 nM. Dyrk1A-IN-4 can be used for the studies of ovarian adenocarcinoma, neuroblastoma and cervical squamous cell carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2091883-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147066.
Dyrk1A-IN-5
Dyrk1A-IN-5 (Compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM. yrk1A-IN-5 exhibits significant selectivity for DYRK1B (IC50 = 600 nM) and CLK1 (IC50 = 500 nM), but shows almost no inhibition of DYRK2 (IC50 > 10 μM). Dyrk1A-IN-5 can be used for Down syndrome research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1685235-41-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146221.
DYRK1-IN-1
DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2814486-79-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132308.
DYRK1-IN-1
DYRK1-IN-1 is a highly selective and ligand efficient DYRK1A inhibitor that inhibits DYRK1A phosphorylation activity with an IC50 of 220 nM. It can be used to study the central nervous system penetrant DYRK1A chemical probe. Synonyms: N,N-dimethyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)-2-pyrimidinamine. Grade: ≥99%. Molecular formula: C12H12N6. Mole weight: 240.26.
DYRKs-IN-1
DYRKs-IN-1 is a potent inhibitor of DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. It has antitumor activity. Synonyms: N-{5-[(3-Amino-1-phenylpropyl)carbamoyl]-2-chlorophenyl}-2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-7-oxo-1,7-dihydropyrido[2,3-d]pyrimidine-6-carboxamide; Pyrido[2,3-d]pyrimidine-6-carboxamide, N-[5-[[(3-amino-1-phenylpropyl)amino]carbonyl]-2-chlorophenyl]-7,8-dihydro-2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-7-oxo-. Grade: ≥95%. CAS No. 1387090-01-8. Molecular formula: C30H30ClN7O4. Mole weight: 588.06.
DYRKs-IN-1 hydrochloride
DYRKs-IN-1 hydrochloride is a potent inhibitor of DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. It has antitumor activity. Synonyms: N-(5-((3-amino-1-phenylpropyl)carbamoyl)-2-chlorophenyl)-2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide hydrochloride. Grade: ≥95%. CAS No. 1386980-55-7. Molecular formula: C30H31Cl2N7O4. Mole weight: 624.52.
DYRKs-IN-1 hydrochloride
DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1386980-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128758A.
DYRKs-IN-2
DYRKs-IN-2 is a potent inhibitor of DYRKs with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. It has antitumor activity. Synonyms: N-(5-(3-Amino-1-phenylpropylcarbamoyl)-2-chlorophenyl)-2-(3-(4-methylpiperazin-1-yl)propylamino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide; N-{5-[(3-Amino-1-phenylpropyl)carbamoyl]-2-chlorophenyl}-2-{[3-(4-methyl-1-piperazinyl)propyl]amino}-7-oxo-1,7-dihydropyrido[2,3-d]pyrimidine-6-carboxamide. Grade: ≥95%. CAS No. 1386980-04-6. Molecular formula: C32H38ClN9O3. Mole weight: 632.16.
DYRKtide
DYRKtide is a biological active peptide. (Dyrktide is designed as the optimal substrate sequence efficiently phosphorylated by DYRK1A, which is a dual-specificity protein kinase that is thought to be involved in brain development.). Uses: Scientific research. Category: Signaling pathways. CAS No. 2250228-51-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5430.
Dysporium (III) oxide
Dysporium (III) oxide
Sarchem Laboratories New Jersey NJ
Dysprosium Acetate
Dysprosium Acetate. Grades: 99.9% Extremely High (>=99%). CAS No. 115280-55-4. Pack Sizes: Gram Quantities: 100 gm , 500 gm. Order Number: 1618.
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Dysprosium Bromide
Dysprosium Bromide. Grades: 99.9% Extremely High (>=99%). CAS No. 14456-48-5. Pack Sizes: Gram Quantities: 100 gm , 500 gm. Order Number: 1633.
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Dysprosium Carbonate
Dysprosium Carbonate. Grades: 99.99% Extremely High (>=99%). CAS No. 38245-35-1. Pack Sizes: Gram Quantities: 25 gm , 100 gm. Order Number: 1636.
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Dysprosium chips
Dysprosium chips. Grades: 99.9% Extremely High (>=99%). CAS No. 7429-91-6. Pack Sizes: Gram Quantities: 10 gm, 50gm. Order Number: 1612.
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Dysprosium Chloride
Dysprosium Chloride. Grades: 99.99% Extremely High (>=99%). CAS No. 15059-52-6. Pack Sizes: Kilogram Quanitites: 1 kg, 5 kg. Order Number: 1640.
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Dysprosium Chloride
Dysprosium Chloride. Grades: 99.9% Extremely High (>=99%). CAS No. 15059-52-6. Pack Sizes: Gram Quantities: 25 gm , 100 gm. Order Number: 1639.
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Dysprosium Chloride, anhydrous
Dysprosium Chloride, anhydrous. Grades: 99.9% Extremely High (>=99%). CAS No. 10025-74-8. Pack Sizes: Gram Quantities: 10 gm, 100 gm. Order Number: 1642.
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Dysprosium (Dy)
Dysprosium (Dy). Alternative Names: High Purity Dysprosium (Dy); 99.9% Dysprosium (Dy); 99.99% Dysprosium (Dy); 99.999% Dysprosium (Dy). Purity: 3N-5N.