A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| DuP 105 | DuP 105, an orally active oxazolidinone, is a new synthetic antimicrobial agent with activity against gram-positive bacteria. Synonyms: Dup-105; DuP105; 4-Methylsulfinylphenyloxooxazolidinylmethylacetamide; Acetamide, N-((3-(4-(methylsulfinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-; (S)-N-[3-(4-Methanesulfinyl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide. Grade: ≥95%. CAS No. 96800-41-8. Molecular formula: C13H16N2O4S. Mole weight: 296.34. |  |
| DuP 697 | DuP 697. Group: Biochemicals. Grades: Purified. CAS No. 88149-94-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| DuP-697 | DuP-697 is a selective COX-2 inhibitor. Synonyms: DuP-697; DuP 697; DuP697; S-6907; S 6907; S6907; BFMT; 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene. CAS No. 88149-94-4. Molecular formula: C17H12BrFO2S2. Mole weight: 411.3. | |
| DuP-697 | DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor (IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively). DuP-697 exerts antiproliferative (IC50 of 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88149-94-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103387. |  |
| DUPA | DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 302941-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111606. | |
| DUPA(OtBu)-OH | DUPA(OtBu)-OH is a PEG linker for antibody-drug-conjugation (ADC). DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. Synonyms: (S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid; L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester; 2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester. Grade: 95%. CAS No. 1026987-94-9. Molecular formula: C23H40N2O9. Mole weight: 488.57. | |
| dUpCp | dUpCp, a nucleoside analogue hailed for its therapeutic potential in treating viral infections such as hepatitis C and HIV, has garnered attention for its capacity to inhibit viral replication and to stymie further infection. What's more, this potent analogous substance holds great promise in fighting cancer, with studies demonstrating its propensity to selectively trigger apoptosis in cancer cells. Although the ramifications of its usage as an antitumor agent call for further inquiry into its efficacy, it's an exciting prospect indeed. Synonyms: dUMPCP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H16N2O10P2(free acid). Mole weight: 386.19 (free acid). | |
| dUpCpp | dUpCpp - a chemical compound utilized in the field of biomedical research - holds promising potential as an enzyme activator which facilitates DNA and RNA replication. By augmenting the function of polymerases essential for viral replication, this unique substance presents a promising target for antiviral drug development. Furthermore, dUpCpp has been utilized to probe and unravel the mechanisms underlying the polymerization of DNA and RNA in a spectrum of systems. Synonyms: dUMPCPP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 170428-84-9. Molecular formula: C10H17N2O13P3.xNa. Mole weight: 466.17 (free acid). | |
| Dupical | Dupical. CAS No. 30168-23-1. VIGON Item # 503212. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, muguet butanal. |  America & Internationally |
| Dupilumab | Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN-668; SAR-231893. CAS No. 1190264-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9926. | |
| Dupilumab | Dupilumab, marketed under the brand name Dupixent, is a monoclonal antibody used to treat several chronic inflammatory conditions. It works by inhibiting the signaling of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are cytokines involved in the inflammatory response. Dupilumab is approved for the treatment of several conditions, including, atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic esophagitis. Synonyms: Immunoglobulin, anti-(human interleukin 4 receptor α) (human REGN668 heavy chain), disulfide with human REGN668 κ-chain, dimer; Dupixent; REGN 668; SAR 231893. CAS No. 1190264-60-8. | |
| Dupilumab (anti-IL-4Rα) | Dupilumab (anti-IL-4Rα) is a fully human anti-interleukin-4 receptor α monoclonal antibody that inhibits both interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling through blockade of the shared IL-4α subunit. Group: Antibodies. Alternative Names: REGN-668, SAR-231893. CAS No. 1190264-60-8. Pack Sizes: 1mg. Product ID: A2038. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |  United States; Europe |
| Duplex 2209, 20 mesh woven from 0.3mm (0.012mm) dia wire | Duplex 2209, 20 mesh woven from 0.3mm (0.012mm) dia wire. |  |
| Duplex 2209, 40 mesh woven from 0.2mm (0.008mm) dia wire | Duplex 2209, 40 mesh woven from 0.2mm (0.008mm) dia wire. | |
| Duplex 2209, 60 mesh woven from 0.15mm (0.006mm) dia wire | Duplex 2209, 60 mesh woven from 0.15mm (0.006mm) dia wire. | |
| dUpNHp | dUpNHp, a noteworthy biochemical research instrument, exhibits extensive applicability in the modification and examination of enzymatic activity within cells. Remarkably, its specificity in targeting and altering the activity of protein kinases and G proteins has proven invaluable within the realm of biomedicine, aiding in the study of prevalent diseases such as diabetes, cancer, and Alzheimer's whilst facilitating the development of new drugs targeted to combat them. Synonyms: dUMPNP; 2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 178809-71-7. Molecular formula: C9H15N3O10P2.xNa. Mole weight: 387.17 (free acid). | |
| dUpNHpp | dUpNHpp, a formidable small molecule inhibitor with potential therapeutic benefits, is a contender in the battle against cancer. Its mode of action rests on disrupting protein-protein interactions, resulting in the arrest of tumor growth. Ovarian and breast cancer, both notorious for their lethality, have been subject to clinical trials with auspicious outcomes. Synonyms: dUMPNPP; 2'-Deoxyuridine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 170428-86-1. Molecular formula: C9H16N3O13P3.xNa. Mole weight: 467.15 (free acid). | |
| DuPont Mask USA | DuPont Mask USA. Product ID: CDC10-0625. Category: Silk Mask Series. Product Keywords: Cosmetic Ingredients; Cosmetic packaging material; DuPont Mask USA; CDC10-0625; Silk Mask series; Lyocell fibers. |  |
| DuPont Mask USA | DuPont Mask USA. Product ID: CDC10-0686. Category: Cosmetic Packaging Material. Product Keywords: Cosmetic Ingredients; Mask; CDC10-0686; DuPont Mask USA; Cosmetic Packaging Material;. | |
| DuPont Three Generations Mask | DuPont Three Generations Mask. Product ID: CDC10-0685. Category: Cosmetic Packaging Material. Product Keywords: Cosmetic Ingredients; Mask; CDC10-0685; DuPont Three Generations Mask; Cosmetic Packaging Material;. | |
| DuPont Three Generations Mask | DuPont Three Generations Mask. Product ID: CDC10-0624. Category: Silk Mask Series. Product Keywords: Cosmetic Ingredients; Cosmetic packaging material; DuPont Three Generations Mask; CDC10-0624; Silk Mask series; Lyocell fibers. | |
| Duralink HTS | Duralink HTS. Molecular formula: C6H12Na2O6S4. Mole weight: 354.4g/mol. IUPAC Name: disodium;1,6-bis(sulfonatosulfanyl)hexane. SMILES: C(CCCSS(=O)(=O)[O-])CCSS(=O)(=O)[O-].[Na+].[Na+]. InChI: InChI=1S/C6H14O6S4.2Na/c7-15(8,9)13-5-3-1-2-4-6-14-16(10,11)12;;/h1-6H2,(H,7,8,9)(H,10,11,12);;/q;2*+1/p-2. | |
| Duramycin | Duramycin. Alternative Names: Ancovenin,2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-,cyclic 6-19)-imine; LANCOVUTIDE; Leucopeptin; UNII-BPR0F3X56H; Lancovutide [INN]. CAS No. 1391-36-2. Purity: 90+%. Product ID: ACM1391362. Molecular formula: C89H125N23O25S3. Mole weight: 2013.28. IUPAC Name: Duramycin. Canonical SMILES: CC1C2C(=O)NC(C(=O)NC(C(=O)NC3CSCC4C(=O)NC(CS1)C(=O)NC(CNCCCCC(NC(=O)C(CSCC(C(=O)NC(C(=O)NC(C(=O)N4)CCC(=O)N)CCCCN)N)NC(=O)C(NC(=O)CNC(=O)C(NC3=O)C(C(=O)O)O)CC(=O)N)C(=O)O)C(=O)NC(C(=O)NCC(=O)N5CCCC5C(=O)NC(C(=O)N2)CC6=CC=CC=C6)CC7=CC=CC=C7)C(C)C)CC8=CC=CC=C8. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Duramycin | Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Moli1901; Lancovutide. CAS No. 1391-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106302. | |
| Duramycin | It is produced by the strain of Streptomyces cinnamomeus. It has activity against gram-positive bacteria, gram-negative bacteria (individual, weak), Mycobacterium and Candida albicans. Synonyms: 27,46-(Methaniminopentaniminomethano)-6,43:15,40-bis(methanothiomethano)pyrrolo[2,1-d1][1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52]thiaheptadecaazacyclopentapentacontine, cyclic peptide deriv.; Antibiotic PA 48009; Lancovutide; Leucopeptin; Ancovenin, 2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-, cyclic 6-19)-imine; Duramycin A. Grade: ≥90%. CAS No. 1391-36-2. Molecular formula: C88H123N23O25S3. Mole weight: 1999.25. | |
| Duramycin B | Duramycins B is a new lanthionine containing antibiotic, has been isolated from Streptoverticillium strain R2075. Duramycins B is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grade: ≥98%. CAS No. 132246-31-2. Molecular formula: C86H127N25O25S3. Mole weight: 2007.27. | |
| Duramycin C | Duramycin C is a new lanthionine containing antibiotic, has been isolated from Streptomyces griseoluteus (R2107). Duramycin C is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grade: ≥98%. CAS No. 132268-38-3. Molecular formula: C82H115N23O27S3. Mole weight: 1951.12. | |
| Durlobactam | Durlobactam is a novel β-lactamase inhibitor. It is designed to combat antibiotic resistance by inhibiting β-lactamase enzymes produced by certain bacteria, which can degrade β-lactam antibiotics. By inhibiting these enzymes, durlobactam allows β-lactam antibiotics to remain effective against resistant bacterial strains. Durlobactam is often combined with other antibiotics to enhance their efficacy, particularly in treating infections caused by multidrug-resistant organisms. Synonyms: Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester; ETX 2514; ETX2514; ETX-2514; (1R,2S,5R)-2-(Aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate; (1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate. Grade: ≥95%. CAS No. 1467829-71-5. Molecular formula: C8H11N3O6S. Mole weight: 277.25. | |
| Durlobactam sodium | Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. Durlobactam sodium can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Synonyms: ETX 2514 sodium; ETX-2514 sodium; ETX2514 sodium; (1R,2S,5R)-2-Carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl sodium sulfate; Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester, sodium salt (1:1); Durlobactam sodium salt; ETX 2514 Sodium salt. Grade: ≥95%. CAS No. 1467157-21-6. Molecular formula: C8H10N3NaO6S. Mole weight: 299.24. | |
| Durlobactam sodium | Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ETX2514. CAS No. 1467157-21-6. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117974. | |
| Durlobactam triethylamine | Durlobactam triethylamine is a combination of durlobactam, a β-lactamase inhibitor, with triethylamine, an organic compound used to form a stable salt. Durlobactam enhances the effectiveness of β-lactam antibiotics by inhibiting the β-lactamase enzymes produced by certain bacteria, which would otherwise degrade the antibiotic and render it ineffective. This combination is used in the treatment of bacterial infections, particularly those caused by multidrug-resistant organisms. Synonyms: ETX 2514 Triethylamine; ETX-2514 Triethylamine; ETX2514 Triethylamine; Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester, compd. with N,N-diethylethanamine (1:1); (1R,2S,5R)-2-(Aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate triethylamine; (1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate triethylamine; Durlobactam TEA salt. Grade: ≥95%. CAS No. 3006792-47-5. Molecular formula: C14H26N4O6S. Mole weight: 378.45. | |
| durvalumab | Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody. It was approved by FDA for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy, or whose disease has progressed within 12 months of receiving platinum-containing chemotherapy before or after surgery. Uses: The treatment of locally advanced or metastatic urothelial carcinoma. Synonyms: Imfinzi. CAS No. 1428935-60-7. Molecular formula: C6502H10018N1742O2024S42. Mole weight: 146.3. | |
| Durvalumab | Durvalumab (MEDI 4736) is an human anti-PD-L1 monoclonal antibody[1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI 4736. CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9919. | |
| Durvalumab (anti-PD-L1) | Durvalumab (anti-PD-L1)(MEDI 4736) is a human anti-PD-L1 protein monoclonal antibody. Durvalumab (anti-PD-L1) completely blocks PD-L1 binding to PD-1 and CD80, IC 50 are 0.1 and 0.04 nM respectively, has anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI 4736 (anti-PD-L1). CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9919A. | |
| Durvalumab (anti-PD-L1) | Durvalumab (anti-PD-L1) is a selective, high affinity human IgG1 mAb that blocks programmed cell death ligand-1 (PD-L1) binding to PD-1 (IC50=0.1 nM) and CD80 (IC50=0.04 nM). MW=146.3 kDa. Group: Antibodies. Alternative Names: MEDI4736. CAS No. 1428935-60-7. Pack Sizes: 5mg. Product ID: A2013. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Dusigitumab | Dusigitumab is a fully human IgG2λ monoclonal antibody that targets IGF-1 and IGF-2 with picomolar binding affinity. Dusigitumab blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R as well as activation of IR-A, thereby inhibiting the activation of downstream signaling pathways. Dusigitumab is applicable to research related to advanced solid tumors and hormone receptor-positive metastatic breast cancer[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: MEDI 573. CAS No. 1204390-13-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99867. | |
| Dusquetide | Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection[1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SGX942. CAS No. 931395-42-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2076. | |
| Dusquetide aceate | Dusquetide aceate modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide aceate shows activity in both reducing inflammation and increasing clearance of bacterial infection. Molecular formula: C27H51N9O7. Mole weight: 613.75. | |
| Dusquetide TFA | Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection. Synonyms: SGX942 TFA. Molecular formula: C27H48F3N9O7. Mole weight: 667.72. | |
| Dustanin | Dustanin is a hopane isolated from Aschersonia. Synonyms: 15alpha,22-dihydroxyhopane; Hopane-15α,22-diol. CAS No. 3607-96-3. Molecular formula: C30H52O2. Mole weight: 444.73. | |
| DUT-8 (Co) | Take your Metal-organic Frameworks (MOFs) Materials research to the next level by the innovative DUT-8 (Co) from CD Bioparticles Drug Delivery. Group: Cobalt-based mofs (co-mof). |  |
| DUT-8 (Ni) | Optimize your research on Ni-MOF with the cutting-edge DUT-8 (Ni) from CD Bioparticles Drug Delivery. Group: Nickel-based mofs (ni-mof). | |
| Dutasteride | Dutasteride. Group: Biochemicals. Alternative Names: (5a, 17b) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide. Grades: Highly Purified. CAS No. 164656-23-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H30F6N2O2. US Biological Life Sciences. | Worldwide |
| Dutasteride | Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Synonyms: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5α,17β)-; (5α,17β)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide; Avodart; Avolve; GG 745; GI 198745; Veltride. Grade: >98%. CAS No. 164656-23-9. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. | |
| Dutasteride | Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GG 745; GI 198745. CAS No. 164656-23-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13613. | |
| Dutasteride | Dutasteride. Uses: For analytical and research use. Category: Pharmacopoeial standards. Alternative Names: GI 206020X, GW 402836X, GI 198745X, GG 745, Dutasteride,1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5alpha,17beta)-, Dutasteride, GW 403358X, (5alpha,17beta)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide, GW 504051X, Veltride, GW 402839X, Avolve, GI 246118X, Avodart, GI 198745, GW 418079X, GI 246071X. CAS No. 164656-23-9. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. IUPAC Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Catalog: APS164656239. SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)Nc5cc(ccc5C(F)(F)F)C(F)(F)F. |  |
| Dutasteride | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H30F6N2O2. CAS No. 164656-23-9. Prepack ID 11556431-25mg. Molecular Weight 528.53. See USA prepack pricing. |  |
| Dutasteride-13C6 | Labeled Dutasteride. Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride. Dutasteride is used in the treatment of benign prostatic hyperplasia. Group: Biochemicals. Alternative Names: (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N-[2, 5-Bis (trifluoromethyl) phenyl]-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide-13C6; (5α,17 β)-. Grades: Highly Purified. CAS No. 1217685-27-2. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Dutasteride-[13C6] | Dutasteride-[13C6] is the labelled analogue of Dutasteride. Dutasteride is a triple 5α-reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone. Dutasteride is a medication primarily used to treat the symptoms of an enlarged prostate. Synonyms: Dutasteride 13C6. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1217685-27-2. Molecular formula: C21[13C]6H30F6N2O2. Mole weight: 534.49. | |
| Dutasteride EP Impurity A | Dutasteride EP Impurity A. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid. CAS No. 104239-97-6. Molecular formula: C19H27NO3. Mole weight: 317.42. Catalog: APB104239976. | |
| Dutasteride EP Impurity B | An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: N,N-Dimethyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide; Dutasteride Dimethyl amide Imp; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N,N,4a,6a-Tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; Dutasteride Impurity B. Grade: ≥95%. Molecular formula: C21H32N2O2. Mole weight: 344.49. | |
| Dutasteride EP Impurity E | An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: Dutasteride Impurity E; 17a-Dutasteride; 17alpha-Dutasteride; (4aR,4bS,6aS,7R,9aS,9bS,11aR)-N-(2,5-Bis(trifluoromethyl)phenyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5αandrost-1-ene-17α-carboxamide; Dutasteride 17-alfa-epimer; Dutasteride 17α-Epimer; 17α-Dutasteride. Grade: ≥95%. CAS No. 2102935-76-0. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. | |
| Dutasteride Impurity B | Dutasteride Impurity B. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N,N,4a,6a-tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. Molecular formula: C21H32N2O2. Mole weight: 344.49. Catalog: APB05236. | |
| Dutasteride Impurity C | Dutasteride Impurity C. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-ethyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate. Molecular formula: C21H31NO3. Mole weight: 345.48. Catalog: APB05235. | |
| Dutasteride Impurity C | Dutasteride Impurity. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 157307-36-3. Molecular formula: C21H31NO3. Mole weight: 345.49. | |
| Dutasteride Impurity D | Dutasteride Impurity D. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7R,9aS,9bS)-N-(2,5-bis(trifluoromethyl)phenyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10-dodecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. Molecular formula: C27H28F6N2O2. Mole weight: 526.51. Catalog: APB05234. | |
| Dutasteride Impurity E | Dutasteride Impurity E. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7R,9aS,9bS,11aR)-N-(2,5-bis(trifluoromethyl)phenyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. CAS No. 1796930-46-5. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. Catalog: APB1796930465. | |
| Dutasteride Impurity F | Dutasteride Impurity F. Uses: For analytical and research use. Alternative Names: (4S,4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(2,5-bis(trifluoromethyl)phenyl)-4-chloro-4a,6a-dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. Molecular formula: C27H31ClF6N2O2. Mole weight: 564.99. Catalog: APB05233. | |
| Dutasteride Impurity F (1-Chloro Dihydro Dutasteride) | 1-Chloro Dihydro Dutasteride is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-4-chlorohexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1365545-42-1. Molecular formula: C27H31ClF6N2O2. Mole weight: 564.99. | |
| Dutasteride Impurity G | Dutasteride Impurity G. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS)-N-(2,5-bis(trifluoromethyl)phenyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10-dodecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. Molecular formula: C27H28F6N2O2. Mole weight: 526.51. Catalog: APB05232. | |
| Dutasteride Impurity G (5,6-Dehydro-17β-dutasteride) | 5,6-Dehydro-dutasteride is an impurity in the synthesis of Dutasteride. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS)-N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10-dodecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1430804-85-5. Molecular formula: C27H28F6N2O2. Mole weight: 526.53. | |
| Dutasteride Impurity H | Dutasteride Impurity H. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(2,5-bis(trifluoromethyl)phenyl)-1-((4aR,4bS,6aS,7R,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbonyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9. Molecular formula: C46H55F6N3O4. Mole weight: 827.94. Catalog: APB05231. | |
| Dutasteride Impurity I | Dutasteride Impurity I. Uses: For analytical and research use. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(2,5-bis(trifluoromethyl)phenyl)-1-((4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbonyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide. CAS No. 1648593-70-7. Molecular formula: C46H55F6N3O4. Mole weight: 827.94. Catalog: APB1648593707. | |
| Dutasteride Impurity J | An intermediate in the synthesis of Dutasteride and Dutasteride Impurity. Synonyms: [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα)]-N-[2,5-Bis(trifluoromethyl)phenyl]-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; (4aR,4bS,6aS,7S,9aS,9bS)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,3,4,4a,4b,5,6,6a. Grade: > 95%. CAS No. 164656-21-7. Molecular formula: C27H30F6N2O2. Mole weight: 528.54. | |
| Dutasteride Impurity L | Dutasteride Impurity L is an impurity of Dutasteride, a medication used to treat benign prostatic hyperplasia (BPH) in men. Synonyms: DTXSID501100113; 1365545-48-7; (4bS,6aS,7S,9aS,9bS)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4b,5,6,6a,7,8,9,9a,9b,10,11-dodecahydro-6a-methyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1365545-48-7. Molecular formula: C26H26F6N2O2. Mole weight: 512.5. | |
| Dutasteride Related Impurity 1 | Dutasteride Related Impurity. Synonyms: (5α,17β)-3-Oxo-4-azaandrost-1-ene-17-carboxamide; [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 104214-61-1. Molecular formula: C19H28N2O2. Mole weight: 316.44. | |
| Dutogliptin | Dutogliptin is a selective and orally active DPP4 inhibitor. It can improve glycaemic control in patients with type 2 diabetes. But phase III clinical trials for the treatment of type 2 diabetes were discontinued. Uses: Type 2 diabetes mellitus. Synonyms: PHX 1149; PHX1149; PHX-1149; (2R)-1-(((3R)-Pyrrolidin-3-ylamino)acetyl)pyrrolidin-2-yl)boronic acid; 890402-81-0 (tartrate salt). Grade: 98%. CAS No. 852329-66-9. Molecular formula: C10H20BN3O3. Mole weight: 241.10. | |
| Dutomycin | It is produced by the strain of Streptomyces sp. 1725. Dutomycin has stronger cytotoxicity. 1 μg/mL of Dutomycin can completely inhibit P388 leukemia cells. Synonyms: 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-((5-((2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-alpha-L-xylo-hexopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, (2S-(2alpha(6aR*,10S*,10aS*),5beta(2Z,4S*),6alpha))-. CAS No. 146663-67-4. Molecular formula: C44H54O17. Mole weight: 854.89. | |
| dUTP diphosphatase | This enzyme has a dual function: on one hand, it removes dUTP from the deoxynucleotide pool, which reduces the probability of this base being incorporated into DNA by DNA polymerases, while on the other hand, it produces the dTTP precursor dUMP. Lack or inhibition of dUTPase action leads to harmful perturbations in the nucleotide pool resulting in increased uracil content of DNA that activates a hyperactive futile cycle of DNA repair. Group: Enzymes. Synonyms: deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5'-triphosphate nucleotidohydrolase; desoxyuridine 5'-triphosphatase. Enzyme Commission Number: EC 3.6.1.23. CAS No. 37289-34-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4607; dUTP diphosphatase; EC 3.6.1.23; 37289-34-2; deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5'-triphosphate nucleotidohydrolase; desoxyuridine 5'-triphosphatase. Cat No: EXWM-4607. |  |
| Duvakitug | Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TEV-48574; SAR-447189; TEV-574. CAS No. 2750005-84-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990006. | |
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